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SIRT6 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS Motifs 51548 sirtuin 6 chr19 - 4182096 - 4187596 4182596 V_SIRT6_01_M01797 Transcription Factor Binding Sites   Download all TFBS in the SIRT6 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints RXRG_nuclearreceptor_full_dimeric_14_2 SELEX + 4186587 4186600 3.0E-06 AGCGTCATGACCTC 14 RXRG_nuclearreceptor_full_dimeric_14_2 SELEX - 4186587 4186600 4.0E-06 GAGGTCATGACGCT 14 MESP1_bHLH_DBD_dimeric_10_1 SELEX - 4182733 4182742 7.0E-06 AACACCTGCA 10 NF-kappaB_MA0061.1 JASPAR - 4182347 4182356 6.0E-06 GGGACTTCCC 10 PAX6_PAX_DBD_monomeric_19_1 SELEX + 4182865 4182883 1.0E-05 TTTTACGGATTAGTAAATT 19 LHX6_homeodomain_full_dimeric_16_1 SELEX - 4181860 4181875 2.0E-06 TAATGAGCGCTGATGG 16 RXRA_nuclearreceptor_full_dimeric_14_2 SELEX + 4186587 4186600 2.0E-06 AGCGTCATGACCTC 14 RXRA_nuclearreceptor_full_dimeric_14_2 SELEX - 4186587 4186600 2.0E-06 GAGGTCATGACGCT 14 TBX5_TBX_DBD_dimeric_20_1 SELEX + 4182190 4182209 0.0E+00 AGGTGTGTTTATTCCCACCT 20 TBX5_TBX_DBD_dimeric_20_1 SELEX - 4182190 4182209 0.0E+00 AGGTGGGAATAAACACACCT 20 Rxra_nuclearreceptor_DBD_dimeric_12_1 SELEX - 4186588 4186599 3.0E-06 AGGTCATGACGC 12 SOX8_HMG_full_dimeric_17_1 SELEX + 4181323 4181339 2.0E-06 CTTCAGTGACAGTGATG 17 SOX8_HMG_full_dimeric_17_1 SELEX - 4181323 4181339 3.0E-06 CATCACTGTCACTGAAG 17 STAT1_MA0137.2 JASPAR + 4180290 4180304 4.0E-06 CATTTCCCAGCAACC 15 STAT1_MA0137.2 JASPAR + 4182230 4182244 4.0E-06 CTCTTCCTGGAACTA 15 Klf4_MA0039.2 JASPAR - 4181243 4181252 3.0E-06 AGGGTGTGGC 10 TCF4_bHLH_full_dimeric_10_1 SELEX - 4182733 4182742 5.0E-06 AACACCTGCA 10 RXRG_nuclearreceptor_DBD_dimeric_14_2 SELEX + 4186587 4186600 2.0E-06 AGCGTCATGACCTC 14 RXRG_nuclearreceptor_DBD_dimeric_14_2 SELEX - 4186587 4186600 3.0E-06 GAGGTCATGACGCT 14 SOX14_HMG_DBD_dimeric_13_1 SELEX + 4181325 4181337 1.0E-05 TCAGTGACAGTGA 13 ELK1_ETS_full_dimeric_17_1 SELEX + 4182581 4182597 0.0E+00 CGCTTCCGCCGGAAGCG 17 ELK1_ETS_full_dimeric_17_1 SELEX - 4182581 4182597 0.0E+00 CGCTTCCGGCGGAAGCG 17 RFX3_RFX_DBD_dimeric_15_1 SELEX + 4181356 4181370 9.0E-06 GGTTTCCATGCAACC 15 MGA_TBX_DBD_dimeric_18_2 SELEX - 4182191 4182208 5.0E-06 GGTGGGAATAAACACACC 18 Lhx3_MA0135.1 JASPAR - 4182872 4182884 6.0E-06 GAATTTACTAATC 13 TBX4_TBX_DBD_dimeric_20_1 SELEX + 4182190 4182209 0.0E+00 AGGTGTGTTTATTCCCACCT 20 TBX4_TBX_DBD_dimeric_20_1 SELEX - 4182190 4182209 0.0E+00 AGGTGGGAATAAACACACCT 20 ZNF143_C2H2_DBD_monomeric_16_1 SELEX + 4182388 4182403 1.0E-06 TTCCCACAATGCCCCC 16 VENTX_homeodomain_DBD_monomeric_9_1 SELEX - 4182177 4182185 5.0E-06 AACGATTAG 9 Klf12_C2H2_DBD_monomeric_15_1 SELEX + 4181242 4181256 1.0E-06 GGCCACACCCTTTAA 15 Stat3_MA0144.1 JASPAR - 4182232 4182241 1.0E-06 TTCCAGGAAG 10 TBX2_TBX_full_dimeric_18_1 SELEX - 4182191 4182208 3.0E-06 GGTGGGAATAAACACACC 18 POU6F2_POU_full_monomeric_10_1 SELEX + 4181868 4181877 8.0E-06 GCTCATTAAA 10 FOXC1_forkhead_DBD_dimeric_13_1 SELEX - 4180384 4180396 6.0E-06 AACAAAACAAAAA 13 TCF3_bHLH_DBD_dimeric_10_1 SELEX - 4182733 4182742 3.0E-06 AACACCTGCA 10 RXRA_nuclearreceptor_DBD_dimeric_14_2 SELEX + 4186587 4186600 2.0E-06 AGCGTCATGACCTC 14 RXRA_nuclearreceptor_DBD_dimeric_14_2 SELEX - 4186587 4186600 1.0E-06 GAGGTCATGACGCT 14 FOXJ2_forkhead_DBD_dimeric_14_1 SELEX - 4180386 4180399 8.0E-06 AAAAACAAAACAAA 14 V_HOXA9_01_M01351 TRANSFAC + 4181866 4181882 4.0E-06 GCGCTCATTAAATGCAT 17 V_FOXP1_01_M00987 TRANSFAC + 4180381 4180400 2.0E-06 ATCTTTTTGTTTTGTTTTTA 20 V_NFKB_C_M00208 TRANSFAC - 4182346 4182357 1.0E-06 AGGGACTTCCCA 12 V_TCF3_01_M01594 TRANSFAC + 4180384 4180396 1.0E-06 TTTTTGTTTTGTT 13 V_NFKB_Q6_01_M00774 TRANSFAC + 4182342 4182357 3.0E-06 TCACTGGGAAGTCCCT 16 V_AML_Q6_M00769 TRANSFAC - 4182276 4182290 3.0E-06 AACTCTGTGGTCACC 15 V_ZFP410_04_M02936 TRANSFAC + 4182326 4182342 5.0E-06 ACTTCCCGCCCCTTCCT 17 V_STAT3STAT3_Q3_M01220 TRANSFAC - 4180289 4180302 0.0E+00 TTGCTGGGAAATGT 14 V_ACAAT_B_M00309 TRANSFAC - 4186687 4186695 8.0E-06 GATTGGTGG 9 V_BCL6_01_M01183 TRANSFAC + 4180383 4180398 1.0E-06 CTTTTTGTTTTGTTTT 16 V_SP1_Q6_01_M00931 TRANSFAC + 4182597 4182606 4.0E-06 GGGGCGGGGC 10 V_TBR2_01_M01774 TRANSFAC + 4180314 4180322 6.0E-06 AGGTGTGAT 9 V_SRY_02_M00160 TRANSFAC - 4180383 4180394 7.0E-06 CAAAACAAAAAG 12 V_SRY_02_M00160 TRANSFAC - 4180388 4180399 5.0E-06 AAAAACAAAACA 12 V_FOXO3A_Q1_M01137 TRANSFAC - 4180389 4180400 6.0E-06 TAAAAACAAAAC 12 V_P50P50_Q3_M01223 TRANSFAC - 4182346 4182358 4.0E-06 GAGGGACTTCCCA 13 V_HNF3_Q6_01_M01012 TRANSFAC + 4180383 4180400 8.0E-06 CTTTTTGTTTTGTTTTTA 18 V_GKLF_02_M01588 TRANSFAC + 4181243 4181254 5.0E-06 GCCACACCCTTT 12 V_TAL1_GATA1_01_M02243 TRANSFAC - 4182697 4182714 5.0E-06 CTTCTGACAGCAGATAAC 18 V_SOX13_03_M02797 TRANSFAC + 4182550 4182565 3.0E-06 ACGGGAACAATAAAGT 16 V_ZFP105_03_M02827 TRANSFAC - 4180381 4180395 3.0E-06 ACAAAACAAAAAGAT 15 V_STAF_01_M00262 TRANSFAC + 4180291 4180312 4.0E-06 ATTTCCCAGCAACCCTTGCAGC 22 V_STAF_01_M00262 TRANSFAC + 4182386 4182407 4.0E-06 TATTCCCACAATGCCCCCCTGC 22 V_RFX1_01_M00280 TRANSFAC - 4181355 4181371 6.0E-06 GGGTTGCATGGAAACCA 17 V_AP1_Q4_M00188 TRANSFAC + 4181812 4181822 3.0E-06 AGTGACTAACA 11 V_SP1_Q6_M00196 TRANSFAC + 4182595 4182607 7.0E-06 GCGGGGCGGGGCG 13 V_IK1_01_M00086 TRANSFAC - 4182384 4182396 1.0E-06 TTGTGGGAATATC 13 V_HNF3_Q6_M00791 TRANSFAC - 4180382 4180394 7.0E-06 CAAAACAAAAAGA 13 V_NKX25_Q5_M01043 TRANSFAC + 4181318 4181327 6.0E-06 TGTCACTTCA 10 V_SREBP_Q6_M01168 TRANSFAC + 4181212 4181226 9.0E-06 TCTATCACACCAGGC 15 V_HOX13_01_M00023 TRANSFAC - 4181793 4181822 7.0E-06 TGTTAGTCACTTTATTATTATTATTATTAT 30 Tal1_Gata1_MA0140.1 JASPAR - 4182697 4182714 5.0E-06 CTTCTGACAGCAGATAAC 18 V_PEBP_Q6_M00984 TRANSFAC + 4182276 4182290 0.0E+00 GGTGACCACAGAGTT 15 V_AP1_C_M00199 TRANSFAC + 4181881 4181889 3.0E-06 ATGAGTCAG 9 V_KLF7_03_M02773 TRANSFAC + 4181240 4181255 9.0E-06 AGGGCCACACCCTTTA 16 V_ISGF3G_03_M02771 TRANSFAC - 4180386 4180400 9.0E-06 TAAAAACAAAACAAA 15 V_AP1_01_M00517 TRANSFAC + 4181879 4181891 1.0E-06 GCATGAGTCAGAA 13 V_STAT3_03_M01595 TRANSFAC - 4180288 4180303 7.0E-06 GTTGCTGGGAAATGTA 16 V_STAT3_03_M01595 TRANSFAC - 4182228 4182243 1.0E-06 AGTTCCAGGAAGAGGG 16 V_IK3_01_M00088 TRANSFAC - 4182384 4182396 4.0E-06 TTGTGGGAATATC 13 V_SOX11_03_M02795 TRANSFAC - 4180385 4180401 5.0E-06 CTAAAAACAAAACAAAA 17 V_ISGF4G_04_M02875 TRANSFAC - 4180387 4180400 8.0E-06 TAAAAACAAAACAA 14 V_FOXO1_Q5_M01216 TRANSFAC - 4180386 4180394 8.0E-06 CAAAACAAA 9 V_FOXO1_Q5_M01216 TRANSFAC - 4180391 4180399 1.0E-06 AAAAACAAA 9 V_SP4_Q5_M01273 TRANSFAC - 4182596 4182606 2.0E-06 GCCCCGCCCCG 11 V_CAAT_01_M00254 TRANSFAC + 4180336 4180347 4.0E-06 TCTGGCCAATGA 12 V_SOX15_03_M02799 TRANSFAC + 4182550 4182566 1.0E-06 ACGGGAACAATAAAGTT 17 V_GATA1_05_M00346 TRANSFAC - 4182696 4182705 2.0E-06 GCAGATAACA 10 V_ALPHACP1_01_M00687 TRANSFAC + 4186687 4186697 6.0E-06 CCACCAATCAG 11 V_FAC1_01_M00456 TRANSFAC - 4180384 4180397 0.0E+00 AAACAAAACAAAAA 14 V_FAC1_01_M00456 TRANSFAC - 4180386 4180399 1.0E-06 AAAAACAAAACAAA 14 V_IPF1_05_M01255 TRANSFAC + 4181868 4181879 9.0E-06 GCTCATTAAATG 12 V_TCFE2A_03_M02823 TRANSFAC + 4182184 4182200 6.0E-06 TTCTCCAGGTGTGTTTA 17 V_FOXL1_02_M02857 TRANSFAC - 4180383 4180398 0.0E+00 AAAACAAAACAAAAAG 16 V_FOXJ3_06_M02855 TRANSFAC - 4180383 4180399 0.0E+00 AAAAACAAAACAAAAAG 17 V_PLAG1_01_M01778 TRANSFAC - 4186569 4186584 4.0E-06 GGGGCAGCAGAGAGGA 16 V_FOXO3_01_M00477 TRANSFAC + 4180384 4180397 6.0E-06 TTTTTGTTTTGTTT 14 V_STAT1STAT1_Q3_M01212 TRANSFAC + 4180291 4180303 6.0E-06 ATTTCCCAGCAAC 13 V_E47_01_M00002 TRANSFAC + 4182731 4182745 5.0E-06 CATGCAGGTGTTTGC 15 V_NFAT2_02_M01749 TRANSFAC - 4186658 4186668 5.0E-06 TTCCATGGAGA 11 V_NFAT2_02_M01749 TRANSFAC + 4186659 4186669 4.0E-06 CTCCATGGAAT 11 V_T3RBETA_Q6_01_M02119 TRANSFAC - 4181291 4181307 9.0E-06 AAGTTACAGGAGGTGAG 17 V_TBX5_Q5_M01044 TRANSFAC - 4180313 4180322 6.0E-06 ATCACACCTG 10 V_SOX21_04_M02907 TRANSFAC - 4182549 4182565 4.0E-06 ACTTTATTGTTCCCGTG 17 V_NFKAPPAB_01_M00054 TRANSFAC - 4182347 4182356 7.0E-06 GGGACTTCCC 10 V_SRF_06_M02916 TRANSFAC - 4180385 4180401 1.0E-06 CTAAAAACAAAACAAAA 17 V_SRF_06_M02916 TRANSFAC - 4180386 4180402 9.0E-06 TCTAAAAACAAAACAAA 17 V_SRF_06_M02916 TRANSFAC - 4180387 4180403 6.0E-06 GTCTAAAAACAAAACAA 17 V_FOXO1_04_M01969 TRANSFAC - 4180375 4180394 8.0E-06 CAAAACAAAAAGATGTGTCC 20 V_GSC_01_M01428 TRANSFAC - 4182866 4182882 0.0E+00 ATTTACTAATCCGTAAA 17 V_FOXO1_01_M00473 TRANSFAC - 4180391 4180400 9.0E-06 TAAAAACAAA 10 V_SOX2_Q6_M01272 TRANSFAC + 4180380 4180395 5.0E-06 CATCTTTTTGTTTTGT 16 V_PPARG_02_M00515 TRANSFAC - 4181912 4181934 3.0E-06 AACGAGGTGAAGATGGCCCCATT 23 V_PITX2_01_M01447 TRANSFAC + 4182866 4182882 2.0E-06 TTTACGGATTAGTAAAT 17 V_FOXO4_01_M00472 TRANSFAC - 4180389 4180399 1.0E-05 AAAAACAAAAC 11 V_LPOLYA_B_M00318 TRANSFAC + 4182557 4182564 7.0E-06 CAATAAAG 8 V_RNF96_01_M01199 TRANSFAC + 4182424 4182433 7.0E-06 GCCCGCGGCC 10 V_OTX1_01_M01366 TRANSFAC + 4182866 4182882 2.0E-06 TTTACGGATTAGTAAAT 17 V_STAT1_05_M01260 TRANSFAC - 4180283 4180304 4.0E-06 GGTTGCTGGGAAATGTAGTCTT 22 V_SMAD1_01_M01590 TRANSFAC - 4180383 4180394 7.0E-06 CAAAACAAAAAG 12 V_SMAD1_01_M01590 TRANSFAC - 4180388 4180399 3.0E-06 AAAAACAAAACA 12 V_AP2_Q3_M00800 TRANSFAC - 4182418 4182433 8.0E-06 GGCCGCGGGCTGGGAG 16 V_NANOG_02_M01247 TRANSFAC - 4180379 4180398 2.0E-06 AAAACAAAACAAAAAGATGT 20 V_NANOG_02_M01247 TRANSFAC - 4180384 4180403 1.0E-06 GTCTAAAAACAAAACAAAAA 20 V_OTX3_01_M01403 TRANSFAC + 4182865 4182881 1.0E-06 TTTTACGGATTAGTAAA 17

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.