Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

FAM59A Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 64762 GRB2 associated, regulator of MAPK1 chr18 - 30049947 - 30055447 30050447 Transcription Factor Binding Sites   Download all TFBS in the FAM59A promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints Hoxc10_homeodomain_DBD_monomeric_10_2 SELEX - 30050049 30050058 6.0E-06 ATAATTAAAA 10 Foxa2_MA0047.2 JASPAR + 30050023 30050034 7.0E-06 TGTTGACTTTTT 12 Hoxd9_homeodomain_DBD_monomeric_10_1 SELEX - 30050049 30050058 3.0E-06 ATAATTAAAA 10 ALX3_homeodomain_full_monomeric_10_1 SELEX + 30050050 30050059 2.0E-06 TTTAATTATA 10 ALX3_homeodomain_full_monomeric_10_1 SELEX - 30050050 30050059 6.0E-06 TATAATTAAA 10 SRY_HMG_DBD_dimeric_15_1 SELEX - 30049897 30049911 7.0E-06 GAGAATATCATTGTG 15 SOX2_HMG_full_dimeric_17_1 SELEX - 30049896 30049912 5.0E-06 TGAGAATATCATTGTGC 17 FOXG1_forkhead_DBD_dimeric_17_1 SELEX + 30049408 30049424 8.0E-06 GAAAACAAGAGAAGACC 17 MEF2D_MADS_DBD_dimeric_12_1 SELEX - 30048853 30048864 6.0E-06 GCTTTAAATAGC 12 FOXC2_forkhead_DBD_monomeric_12_1 SELEX - 30050021 30050032 2.0E-06 AAAGTCAACATA 12 NR2E1_nuclearreceptor_full_monomeric_9_1 SELEX - 30050025 30050033 2.0E-06 AAAAGTCAA 9 Dlx1_homeodomain_DBD_monomeric_8_1 SELEX - 30050051 30050058 4.0E-06 ATAATTAA 8 FOXC1_forkhead_DBD_monomeric_11_1 SELEX - 30050022 30050032 4.0E-06 AAAGTCAACAT 11 Alx1_homeodomain_DBD_monomeric_10_1 SELEX + 30050050 30050059 4.0E-06 TTTAATTATA 10 Alx1_homeodomain_DBD_monomeric_10_1 SELEX - 30050050 30050059 6.0E-06 TATAATTAAA 10 MEF2A_MADS_DBD_dimeric_12_1 SELEX - 30048853 30048864 8.0E-06 GCTTTAAATAGC 12 MEF2A_MADS_DBD_dimeric_12_1 SELEX + 30053508 30053519 7.0E-06 GATAATAATAGT 12 Pax4_MA0068.1 JASPAR + 30048855 30048884 9.0E-06 TATTTAAAGCACACAACATTTTCCCACCCC 30 Pax4_MA0068.1 JASPAR + 30053498 30053527 8.0E-06 GAAAAATGAAGATAATAATAGTACTCATCT 30 HOXB5_homeodomain_DBD_monomeric_10_1 SELEX - 30050050 30050059 5.0E-06 TATAATTAAA 10 MEF2B_MADS_full_dimeric_12_1 SELEX - 30048853 30048864 3.0E-06 GCTTTAAATAGC 12 MEF2B_MADS_full_dimeric_12_1 SELEX + 30053508 30053519 8.0E-06 GATAATAATAGT 12 MEF2A_MA0052.1 JASPAR + 30048854 30048863 4.0E-06 CTATTTAAAG 10 FOXJ3_forkhead_DBD_dimeric_14_1 SELEX - 30050023 30050036 2.0E-06 AAAAAAAGTCAACA 14 HOXB2_homeodomain_DBD_monomeric_10_1 SELEX - 30050050 30050059 5.0E-06 TATAATTAAA 10 DLX6_homeodomain_DBD_monomeric_8_1 SELEX - 30050051 30050058 9.0E-06 ATAATTAA 8 VAX1_homeodomain_DBD_monomeric_8_1 SELEX + 30050051 30050058 9.0E-06 TTAATTAT 8 MIXL1_homeodomain_full_monomeric_10_1 SELEX + 30050050 30050059 1.0E-05 TTTAATTATA 10 MIXL1_homeodomain_full_monomeric_10_1 SELEX - 30050050 30050059 6.0E-06 TATAATTAAA 10 DLX3_homeodomain_DBD_monomeric_8_1 SELEX - 30050051 30050058 9.0E-06 ATAATTAA 8 SOX15_HMG_full_dimeric_15_1 SELEX - 30049897 30049911 6.0E-06 GAGAATATCATTGTG 15 SOX14_HMG_DBD_dimeric_12_1 SELEX - 30049899 30049910 2.0E-06 AGAATATCATTG 12 NRL_bZIP_DBD_monomeric_11_1 SELEX + 30050303 30050313 6.0E-06 TAAGTGCTGAC 11 GSX2_homeodomain_DBD_monomeric_10_1 SELEX - 30050050 30050059 5.0E-06 TATAATTAAA 10 HOXB3_homeodomain_DBD_monomeric_10_1 SELEX - 30050050 30050059 9.0E-06 TATAATTAAA 10 ZNF282_C2H2_DBD_monomeric_17_1 SELEX - 30053464 30053480 2.0E-06 GTTTCCCATGACATTAA 17 SPDEF_ETS_full_monomeric_11_1 SELEX - 30045439 30045449 6.0E-06 TCCCGGATGTG 3 Sox3_HMG_DBD_dimeric_17_1 SELEX + 30049896 30049912 1.0E-05 GCACAATGATATTCTCA 17 Sox1_HMG_DBD_dimeric_15_1 SELEX - 30049897 30049911 7.0E-06 GAGAATATCATTGTG 15 MNX1_homeodomain_DBD_monomeric_10_1 SELEX - 30050050 30050059 3.0E-06 TATAATTAAA 10 E2F2_E2F_DBD_dimeric_18_1 SELEX - 30050035 30050052 9.0E-06 AAAAAGGACGCCCTAAAA 18 FOXB1_forkhead_DBD_monomeric_11_1 SELEX - 30050022 30050032 6.0E-06 AAAGTCAACAT 11 HOXA10_homeodomain_DBD_monomeric_11_1 SELEX - 30050049 30050059 9.0E-06 TATAATTAAAA 11 DLX5_homeodomain_FL_monomeric_8_1 SELEX - 30050051 30050058 8.0E-06 ATAATTAA 8 FOXJ2_forkhead_DBD_dimeric_14_1 SELEX - 30050023 30050036 6.0E-06 AAAAAAAGTCAACA 14 V_FOXP1_01_M00987 TRANSFAC - 30053499 30053518 6.0E-06 CTATTATTATCTTCATTTTT 20 V_CDP_03_M01342 TRANSFAC + 30050839 30050855 6.0E-06 ACTGACTAATCAACAAG 17 V_SRY_07_M02813 TRANSFAC + 30053505 30053520 5.0E-06 GAAGATAATAATAGTA 16 V_SRY_07_M02813 TRANSFAC - 30053505 30053520 4.0E-06 TACTATTATTATCTTC 16 V_FOXA2_04_M02749 TRANSFAC - 30050018 30050034 4.0E-06 AAAAAGTCAACATAGGG 17 V_XPF1_Q6_M00684 TRANSFAC - 30049261 30049270 1.0E-06 TCAGAAGAAC 10 V_DLX3_01_M01400 TRANSFAC - 30050047 30050063 9.0E-06 GCAGTATAATTAAAAAG 17 V_MAFB_05_M02775 TRANSFAC + 30050302 30050318 5.0E-06 GTAAGTGCTGACCAGGA 17 V_FOXO4_02_M00476 TRANSFAC - 30049405 30049418 1.0E-05 CTCTTGTTTTCATC 14 V_FOXJ2_02_M00423 TRANSFAC + 30048864 30048877 8.0E-06 CACACAACATTTTC 14 V_MEF2_02_M00231 TRANSFAC - 30048849 30048870 0.0E+00 TTGTGTGCTTTAAATAGCATCT 22 V_ZFP740_03_M02834 TRANSFAC + 30048875 30048890 6.0E-06 TTCCCACCCCCACTCG 16 V_SRY_02_M00160 TRANSFAC + 30049750 30049761 3.0E-06 TTAAACAAAACA 12 V_FOXO3A_Q1_M01137 TRANSFAC + 30049407 30049418 6.0E-06 TGAAAACAAGAG 12 V_HNF3_Q6_01_M01012 TRANSFAC + 30050018 30050035 5.0E-06 CCCTATGTTGACTTTTTT 18 V_CUX1_03_M02958 TRANSFAC + 30050839 30050855 6.0E-06 ACTGACTAATCAACAAG 17 V_NKX61_03_M01489 TRANSFAC + 30050046 30050062 7.0E-06 CCTTTTTAATTATACTG 17 V_DLX2_01_M01468 TRANSFAC - 30050046 30050061 1.0E-05 AGTATAATTAAAAAGG 16 V_SOX21_03_M02803 TRANSFAC + 30053505 30053520 7.0E-06 GAAGATAATAATAGTA 16 V_MEF2A_Q6_M02024 TRANSFAC + 30048855 30048864 4.0E-06 TATTTAAAGC 10 V_PAX_Q6_M00808 TRANSFAC + 30050260 30050270 2.0E-06 CTGGGACTCAC 11 V_BARBIE_01_M00238 TRANSFAC - 30051018 30051032 3.0E-06 AGCTAAAGCTTGCGG 15 V_ELF4_04_M02850 TRANSFAC - 30050027 30050043 2.0E-06 GCCCTAAAAAAAAAGTC 17 V_GC_01_M00255 TRANSFAC - 30050913 30050926 6.0E-06 TGGGGGCGGAGCGG 14 V_POU3F2_01_M00463 TRANSFAC + 30053503 30053516 5.0E-06 ATGAAGATAATAAT 14 V_LMX1_01_M01409 TRANSFAC - 30050046 30050062 3.0E-06 CAGTATAATTAAAAAGG 17 V_LMX1_01_M01409 TRANSFAC + 30050047 30050063 8.0E-06 CTTTTTAATTATACTGC 17 V_ZFP105_03_M02827 TRANSFAC - 30050045 30050059 1.0E-06 TATAATTAAAAAGGA 15 V_NKX61_01_M00424 TRANSFAC + 30050048 30050060 1.0E-05 TTTTTAATTATAC 13 V_RSRFC4_Q2_M00407 TRANSFAC - 30048850 30048866 8.0E-06 GTGCTTTAAATAGCATC 17 V_RSRFC4_Q2_M00407 TRANSFAC + 30053506 30053522 8.0E-06 AAGATAATAATAGTACT 17 V_SP1_Q6_M00196 TRANSFAC - 30050914 30050926 9.0E-06 TGGGGGCGGAGCG 13 V_IRF3_Q3_M01279 TRANSFAC + 30045576 30045588 2.0E-06 TTCCTTTTCCTTT 13 V_MAZ_Q6_01_M02023 TRANSFAC + 30049968 30049981 1.0E-06 GAGGGTGGGGAGGG 14 V_MAZ_Q6_01_M02023 TRANSFAC - 30050769 30050782 1.0E-06 GGCGGAGGGAAGGA 14 V_MEF2_03_M00232 TRANSFAC - 30048849 30048870 0.0E+00 TTGTGTGCTTTAAATAGCATCT 22 V_ASCL2_03_M02737 TRANSFAC + 30049323 30049339 1.0E-05 TTCCACAGCTGCCCCAC 17 V_OCT1_04_M00138 TRANSFAC + 30053495 30053517 3.0E-06 TCTGAAAAATGAAGATAATAATA 23 V_SP1SP3_Q4_M01219 TRANSFAC + 30050699 30050709 5.0E-06 CCGCCTCCTCC 11 V_MEF2_04_M00233 TRANSFAC - 30048849 30048870 0.0E+00 TTGTGTGCTTTAAATAGCATCT 22 V_MEF2_Q6_01_M00941 TRANSFAC + 30048852 30048863 5.0E-06 TGCTATTTAAAG 12 V_HB24_01_M01399 TRANSFAC + 30050045 30050059 3.0E-06 TCCTTTTTAATTATA 15 V_ARID3A_04_M02735 TRANSFAC - 30050046 30050062 5.0E-06 CAGTATAATTAAAAAGG 17 V_ARID3A_04_M02735 TRANSFAC + 30050047 30050063 5.0E-06 CTTTTTAATTATACTGC 17 V_HIC1_02_M01072 TRANSFAC - 30050514 30050528 0.0E+00 CCCGGCTGCCCGCGG 15 V_LIM1_01_M01418 TRANSFAC - 30050046 30050062 5.0E-06 CAGTATAATTAAAAAGG 17 V_DLX7_01_M01486 TRANSFAC - 30050047 30050063 3.0E-06 GCAGTATAATTAAAAAG 17 V_IPF1_05_M01255 TRANSFAC - 30050048 30050059 5.0E-06 TATAATTAAAAA 12 V_CACBINDINGPROTEIN_Q6_M00720 TRANSFAC + 30049968 30049976 8.0E-06 GAGGGTGGG 9 V_PDEF_01_M02040 TRANSFAC - 30045439 30045448 1.0E-05 CCCGGATGTG 2 V_FOXL1_04_M02753 TRANSFAC - 30050018 30050034 3.0E-06 AAAAAGTCAACATAGGG 17 V_ZSCAN4_04_M02942 TRANSFAC + 30048859 30048874 0.0E+00 TAAAGCACACAACATT 16 V_GATA3_02_M00350 TRANSFAC + 30053505 30053514 1.0E-05 GAAGATAATA 10 V_NKX61_02_M01469 TRANSFAC + 30050046 30050061 5.0E-06 CCTTTTTAATTATACT 16 V_ZFP206_01_M01742 TRANSFAC - 30050865 30050875 4.0E-06 TGCGCAGGCGT 11 V_LMX1B_01_M01363 TRANSFAC + 30050046 30050062 9.0E-06 CCTTTTTAATTATACTG 17 V_FOXO3_01_M00477 TRANSFAC - 30049405 30049418 5.0E-06 CTCTTGTTTTCATC 14 V_FOXA2_03_M02260 TRANSFAC + 30050023 30050034 7.0E-06 TGTTGACTTTTT 12 V_RSRFC4_01_M00026 TRANSFAC + 30048851 30048866 7.0E-06 ATGCTATTTAAAGCAC 16 V_R_01_M00273 TRANSFAC + 30051156 30051176 7.0E-06 CGCTCCCTGAGTCGTGGTGTC 21 V_SRF_06_M02916 TRANSFAC + 30049748 30049764 4.0E-06 GGTTAAACAAAACAGAC 17 V_SRF_06_M02916 TRANSFAC - 30050026 30050042 6.0E-06 CCCTAAAAAAAAAGTCA 17 V_MEF2A_05_M01301 TRANSFAC + 30048852 30048863 4.0E-06 TGCTATTTAAAG 12 V_GATA6_04_M02757 TRANSFAC + 30053502 30053518 6.0E-06 AATGAAGATAATAATAG 17 V_ZFP128_04_M02932 TRANSFAC + 30050048 30050061 8.0E-06 TTTTTAATTATACT 14 V_ZFP128_04_M02932 TRANSFAC - 30050048 30050061 6.0E-06 AGTATAATTAAAAA 14 V_GFI1_Q6_01_M02010 TRANSFAC + 30050069 30050078 2.0E-06 CTCTGATTTC 10 V_HOXD10_01_M01375 TRANSFAC - 30050045 30050061 5.0E-06 AGTATAATTAAAAAGGA 17 V_RNF96_01_M01199 TRANSFAC - 30050512 30050521 7.0E-06 GCCCGCGGCC 10 V_RNF96_01_M01199 TRANSFAC - 30050652 30050661 7.0E-06 GCCCGCAGCC 10 V_TCF3_05_M02920 TRANSFAC - 30050029 30050043 3.0E-06 GCCCTAAAAAAAAAG 15 V_GLIS2_04_M02863 TRANSFAC - 30050048 30050061 1.0E-06 AGTATAATTAAAAA 14 V_FOXK1_03_M02752 TRANSFAC - 30050018 30050034 5.0E-06 AAAAAGTCAACATAGGG 17 V_PAX4_04_M00380 TRANSFAC + 30053499 30053528 1.0E-06 AAAAATGAAGATAATAATAGTACTCATCTC 30 V_SOX14_03_M02798 TRANSFAC + 30053505 30053520 9.0E-06 GAAGATAATAATAGTA 16 V_SOX14_03_M02798 TRANSFAC - 30053505 30053520 8.0E-06 TACTATTATTATCTTC 16

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.