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LRRC59 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 55379 leucine rich repeat containing 59 chr17 - 48474414 - 48479914 48474914 Transcription Factor Binding Sites   Download all TFBS in the LRRC59 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints NFIA_NFI_full_dimeric_15_1 SELEX - 48474370 48474384 3.0E-06 TTGGCGCAGTTCCAG 15 SPIC_ETS_full_monomeric_14_1 SELEX + 48472228 48472241 7.0E-06 CGAAACAGGAAGGA 14 THRA_nuclearreceptor_FL_dimeric_18_1 SELEX + 48475122 48475139 5.0E-06 CTGACCTCATCAGATCAC 18 THRA_nuclearreceptor_FL_dimeric_18_1 SELEX - 48475122 48475139 0.0E+00 GTGATCTGATGAGGTCAG 18 ZNF75A_C2H2_DBD_monomeric_12_1 SELEX - 48473907 48473918 5.0E-06 CCTTTTCCCACT 12 ZBTB7B_C2H2_full_monomeric_12_1 SELEX + 48472220 48472231 9.0E-06 TCAACCCCCGAA 12 HINFP1_C2H2_full_monomeric_12_1 SELEX + 48478873 48478884 8.0E-06 CAAGGTCCGCTT 12 NFIX_NFI_full_dimeric_15_2 SELEX + 48474370 48474384 8.0E-06 CTGGAACTGCGCCAA 15 GATA5_GATA_DBD_monomeric_8_1 SELEX - 48478918 48478925 7.0E-06 AGATAAGA 8 KLF13_C2H2_full_monomeric_18_1 SELEX + 48474944 48474961 9.0E-06 CGGGCACGCCCCCTGGTG 18 GATA4_GATA_DBD_monomeric_8_1 SELEX - 48478918 48478925 7.0E-06 AGATAAGA 8 Klf4_MA0039.2 JASPAR - 48474169 48474178 2.0E-06 TGGGTGTGGC 10 THRB_nuclearreceptor_DBD_dimeric_18_1 SELEX + 48475122 48475139 1.0E-06 CTGACCTCATCAGATCAC 18 THRB_nuclearreceptor_DBD_dimeric_18_1 SELEX - 48475122 48475139 1.0E-06 GTGATCTGATGAGGTCAG 18 TFAP2B_TFAP_DBD_dimeric_12_1 SELEX - 48474109 48474120 5.0E-06 AGCCCTGAGGCA 12 CLOCK_bHLH_DBD_dimeric_10_1 SELEX - 48474388 48474397 7.0E-06 TACACGTGTC 10 ELF3_ETS_full_monomeric_13_1 SELEX - 48474875 48474887 6.0E-06 GACACGGAAGTGG 13 RARA_nuclearreceptor_full_dimeric_17_1 SELEX - 48475192 48475208 6.0E-06 GGGTTAAGTAGAGGACA 17 Gata1_MA0035.2 JASPAR - 48478917 48478927 2.0E-06 TGAGATAAGAA 11 Gata1_MA0035.2 JASPAR - 48478950 48478960 1.0E-06 AGAGATAAGGA 11 GATA3_GATA_full_monomeric_8_1 SELEX - 48478918 48478925 7.0E-06 AGATAAGA 8 MZF1_5-13_MA0057.1 JASPAR + 48473894 48473903 4.0E-06 GGAGGGGGAA 10 TBX20_TBX_full_dimeric_16_1 SELEX - 48472199 48472214 8.0E-06 GGGTGGGAGGGTGTCA 16 Stat3_MA0144.1 JASPAR - 48474145 48474154 7.0E-06 TTCTAGGAAG 10 IRF9_IRF_full_trimeric_15_1 SELEX + 48474468 48474482 7.0E-06 AAAGAAAAGGAAACT 15 NFIB_NFI_full_dimeric_15_1 SELEX - 48474370 48474384 2.0E-06 TTGGCGCAGTTCCAG 15 TFAP2C_TFAP_full_dimeric_12_1 SELEX - 48474109 48474120 8.0E-06 AGCCCTGAGGCA 12 ELF5_ETS_full_monomeric_11_1 SELEX - 48474876 48474886 7.0E-06 ACACGGAAGTG 11 ELF3_ETS_DBD_monomeric_12_1 SELEX - 48474876 48474887 8.0E-06 GACACGGAAGTG 12 Mafb_bZIP_DBD_dimeric_18_1 SELEX - 48475118 48475135 7.0E-06 TCTGATGAGGTCAGTATT 18 THRB_nuclearreceptor_DBD_dimeric_19_1 SELEX + 48474587 48474605 2.0E-06 GGGACCTCATTCAGGTCGC 19 THRB_nuclearreceptor_DBD_dimeric_19_1 SELEX - 48474587 48474605 2.0E-06 GCGACCTGAATGAGGTCCC 19 IRF3_IRF_full_trimeric_21_1 SELEX + 48474469 48474489 2.0E-06 AAGAAAAGGAAACTGATGCTT 21 RREB1_MA0073.1 JASPAR + 48474760 48474779 3.0E-06 CCCCCACCCAAACGACGACG 20 RXR_RAR_DR5_MA0159.1 JASPAR - 48475192 48475208 4.0E-06 GGGTTAAGTAGAGGACA 17 V_STAT5A_Q6_M01890 TRANSFAC - 48474146 48474158 4.0E-06 GCTCTTCTAGGAA 13 V_BCL6_Q3_01_M02085 TRANSFAC + 48474145 48474154 2.0E-06 CTTCCTAGAA 10 V_EVI1_05_M00082 TRANSFAC - 48478915 48478925 2.0E-06 AGATAAGAAAA 11 V_GATA1_Q6_M02004 TRANSFAC - 48478916 48478930 1.0E-06 AAATGAGATAAGAAA 15 V_SOX40_04_M02908 TRANSFAC - 48478957 48478972 2.0E-06 TTTTTTTATAATAGAG 16 V_SRY_07_M02813 TRANSFAC + 48478957 48478972 9.0E-06 CTCTATTATAAAAAAA 16 V_SRY_07_M02813 TRANSFAC - 48478957 48478972 8.0E-06 TTTTTTTATAATAGAG 16 V_GATA2_02_M00348 TRANSFAC - 48478918 48478927 8.0E-06 TGAGATAAGA 10 V_GATA2_02_M00348 TRANSFAC - 48478951 48478960 7.0E-06 AGAGATAAGG 10 V_HMGIY_Q3_M01010 TRANSFAC + 48473820 48473834 5.0E-06 AATGTAATTTATCAA 15 V_DR4_Q2_M00965 TRANSFAC + 48475192 48475208 2.0E-06 TGTCCTCTACTTAACCC 17 V_IRF2_Q6_M01882 TRANSFAC + 48474469 48474484 1.0E-06 AAGAAAAGGAAACTGA 16 V_IRF3_05_M02767 TRANSFAC + 48474470 48474483 1.0E-06 AGAAAAGGAAACTG 14 V_GATA_C_M00203 TRANSFAC - 48478915 48478925 1.0E-06 AGATAAGAAAA 11 V_GKLF_02_M01588 TRANSFAC + 48474169 48474180 4.0E-06 GCCACACCCAGG 12 V_AFP1_Q6_M00616 TRANSFAC - 48473821 48473831 3.0E-06 ATAAATTACAT 11 V_CACCCBINDINGFACTOR_Q6_M00721 TRANSFAC - 48474761 48474776 2.0E-06 CGTCGTTTGGGTGGGG 16 V_PU1_Q4_M01172 TRANSFAC - 48472229 48472247 4.0E-06 TGCATCTCCTTCCTGTTTC 19 V_SOX21_03_M02803 TRANSFAC + 48478957 48478972 2.0E-06 CTCTATTATAAAAAAA 16 V_SOX21_03_M02803 TRANSFAC - 48478957 48478972 1.0E-06 TTTTTTTATAATAGAG 16 V_STAT4_Q4_M01666 TRANSFAC + 48474146 48474159 9.0E-06 TTCCTAGAAGAGCC 14 V_TAL1_GATA1_01_M02243 TRANSFAC - 48478919 48478936 7.0E-06 CAGGACAAATGAGATAAG 18 V_TAL1_GATA1_01_M02243 TRANSFAC - 48478952 48478969 1.0E-06 TTTTATAATAGAGATAAG 18 V_LXRB_RXRA_Q5_M02021 TRANSFAC - 48475116 48475130 0.0E+00 TGAGGTCAGTATTGG 15 V_BCL6_02_M01185 TRANSFAC + 48474090 48474103 8.0E-06 TACTTTCTTCGAGT 14 V_PPARGRXRA_01_M02262 TRANSFAC + 48475070 48475084 8.0E-06 CGAGGCGAAAGGGCA 15 V_ELF4_04_M02850 TRANSFAC + 48478960 48478976 8.0E-06 TATTATAAAAAAACCGA 17 V_FKLF_Q5_M01837 TRANSFAC - 48472206 48472215 2.0E-06 GGGGTGGGAG 10 V_IRF4_04_M02872 TRANSFAC + 48474219 48474233 6.0E-06 TTCATTCTCGAATAC 15 V_OCT1_05_M00161 TRANSFAC + 48478849 48478862 5.0E-06 AGCCTTTCCATGTT 14 V_MEF2_03_M00232 TRANSFAC - 48478954 48478975 8.0E-06 CGGTTTTTTTATAATAGAGATA 22 V_TATA_C_M00216 TRANSFAC - 48474463 48474472 3.0E-06 TCTTTAAAAA 10 V_ISRE_01_M00258 TRANSFAC - 48474469 48474483 1.0E-06 CAGTTTCCTTTTCTT 15 Tal1_Gata1_MA0140.1 JASPAR - 48478919 48478936 7.0E-06 CAGGACAAATGAGATAAG 18 Tal1_Gata1_MA0140.1 JASPAR - 48478952 48478969 1.0E-06 TTTTATAATAGAGATAAG 18 V_MEF2_04_M00233 TRANSFAC - 48474457 48474478 5.0E-06 TCCTTTTCTTTAAAAAGAAGCG 22 V_GATA1_09_M02254 TRANSFAC - 48478917 48478927 2.0E-06 TGAGATAAGAA 11 V_GATA1_09_M02254 TRANSFAC - 48478950 48478960 1.0E-06 AGAGATAAGGA 11 V_ISGF3G_03_M02771 TRANSFAC + 48474470 48474484 2.0E-06 AGAAAAGGAAACTGA 15 V_SMAD4_Q6_M00733 TRANSFAC + 48474119 48474133 1.0E-06 CTCGGGCAGCCAGCT 15 V_PPARA_02_M00518 TRANSFAC - 48475134 48475152 6.0E-06 CAGGGGGATTGGGGTGATC 19 V_TBP_06_M02814 TRANSFAC + 48478957 48478972 3.0E-06 CTCTATTATAAAAAAA 16 V_TBP_06_M02814 TRANSFAC + 48478959 48478974 7.0E-06 CTATTATAAAAAAACC 16 V_MZF1_02_M00084 TRANSFAC + 48473891 48473903 1.0E-06 GTGGGAGGGGGAA 13 V_MTF1_06_M02882 TRANSFAC - 48478912 48478925 0.0E+00 AGATAAGAAAAAGG 14 V_MTF1_06_M02882 TRANSFAC + 48478959 48478972 5.0E-06 CTATTATAAAAAAA 14 V_MTF1_06_M02882 TRANSFAC + 48478960 48478973 2.0E-06 TATTATAAAAAAAC 14 V_TAL1_01_M01591 TRANSFAC - 48474468 48474480 2.0E-06 TTTCCTTTTCTTT 13 V_TAL1_01_M01591 TRANSFAC + 48478948 48478960 0.0E+00 CCTCCTTATCTCT 13 V_HOXB8_01_M01451 TRANSFAC - 48472301 48472316 6.0E-06 TCTTGTAATAAACTGA 16 V_GATA1_04_M00128 TRANSFAC - 48478916 48478928 9.0E-06 ATGAGATAAGAAA 13 V_SIRT6_01_M01797 TRANSFAC - 48478918 48478925 7.0E-06 AGATAAGA 8 V_GATA3_02_M00350 TRANSFAC - 48478918 48478927 5.0E-06 TGAGATAAGA 10 V_XBP1_01_M00251 TRANSFAC - 48474384 48474400 4.0E-06 ATGTACACGTGTCACTT 17 V_AIRE_01_M00999 TRANSFAC - 48478967 48478992 0.0E+00 ATTGAACTTGGCAACTTCGGTTTTTT 26 V_TCF7_04_M02921 TRANSFAC + 48478957 48478971 0.0E+00 CTCTATTATAAAAAA 15 V_P53_01_M00034 TRANSFAC + 48474935 48474954 5.0E-06 GAGCGTGTGCGGGCACGCCC 20 V_P53_01_M00034 TRANSFAC - 48474935 48474954 6.0E-06 GGGCGTGCCCGCACACGCTC 20 V_SREBP_Q3_M00776 TRANSFAC + 48475132 48475143 3.0E-06 CAGATCACCCCA 12 V_RXR_RAR_01_M02272 TRANSFAC - 48475192 48475208 4.0E-06 GGGTTAAGTAGAGGACA 17 V_IRF1_Q6_01_M01881 TRANSFAC - 48474470 48474483 7.0E-06 CAGTTTCCTTTTCT 14 V_LXRA_RXRA_Q3_M00647 TRANSFAC - 48475118 48475132 2.0E-06 GATGAGGTCAGTATT 15 V_GATA2_03_M00349 TRANSFAC - 48478918 48478927 3.0E-06 TGAGATAAGA 10 V_SRF_06_M02916 TRANSFAC + 48478961 48478977 1.0E-06 ATTATAAAAAAACCGAA 17 V_SATB1_01_M01232 TRANSFAC + 48478960 48478971 9.0E-06 TATTATAAAAAA 12 V_EKLF_Q5_M01874 TRANSFAC + 48474170 48474179 5.0E-06 CCACACCCAG 10 V_PIT1_Q6_M00802 TRANSFAC + 48474217 48474234 6.0E-06 CATTCATTCTCGAATACA 18 V_GATA5_03_M02756 TRANSFAC - 48478914 48478930 1.0E-06 AAATGAGATAAGAAAAA 17 V_GATA5_03_M02756 TRANSFAC - 48478947 48478963 9.0E-06 AATAGAGATAAGGAGGA 17 V_MYCMAX_03_M00615 TRANSFAC + 48474383 48474402 5.0E-06 AAAGTGACACGTGTACATCC 20 V_MYCMAX_03_M00615 TRANSFAC - 48474383 48474402 5.0E-06 GGATGTACACGTGTCACTTT 20 V_GATA6_04_M02757 TRANSFAC - 48478914 48478930 0.0E+00 AAATGAGATAAGAAAAA 17 V_GATA6_04_M02757 TRANSFAC - 48478947 48478963 2.0E-06 AATAGAGATAAGGAGGA 17 V_GLIS2_04_M02863 TRANSFAC + 48478958 48478971 1.0E-06 TCTATTATAAAAAA 14 V_EVI1_03_M00080 TRANSFAC - 48478915 48478925 6.0E-06 AGATAAGAAAA 11 PPARG_RXRA_MA0065.2 JASPAR + 48475070 48475084 8.0E-06 CGAGGCGAAAGGGCA 15 V_AP2_Q3_M00800 TRANSFAC - 48474812 48474827 8.0E-06 GCCAGCGGGCGGAGGC 16 V_T3RALPHA_Q6_M01724 TRANSFAC - 48475122 48475132 5.0E-06 GATGAGGTCAG 11

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.