Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

KLHDC8B Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 200942 kelch domain containing 8B chr3 + 49204017 - 49209517 49209017 Transcription Factor Binding Sites   Download all TFBS in the KLHDC8B promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints CTCF_MA0139.1 JASPAR + 49208616 49208634 0.0E+00 TGGCCTCCAGGGGGCGCCG 19 CTCF_MA0139.1 JASPAR - 49211979 49211997 4.0E-06 AGACCACCAGGGGTCAGAG 19 MYBL2_MYB_DBD_dimeric_15_1 SELEX + 49208860 49208874 3.0E-06 GTCCGTTTATCTGTC 15 VSX2_homeodomain_DBD_monomeric_8_1 SELEX - 49211444 49211451 5.0E-06 CTAATTAT 8 ALX3_homeodomain_full_monomeric_10_1 SELEX - 49211443 49211452 2.0E-06 TCTAATTATA 10 MEF2D_MADS_DBD_dimeric_12_1 SELEX + 49210885 49210896 3.0E-06 GTTATAAATAGT 12 MEF2D_MADS_DBD_dimeric_12_1 SELEX - 49210885 49210896 9.0E-06 ACTATTTATAAC 12 ESR2_MA0258.1 JASPAR + 49210998 49211015 1.0E-05 AAAGGCCAAGCTGATCTG 18 RFX4_RFX_DBD_dimeric_16_1 SELEX - 49211020 49211035 5.0E-06 GGCTTCCATGGCAACC 16 RFX4_RFX_DBD_dimeric_16_1 SELEX - 49211407 49211422 4.0E-06 AGATGCTATGGCAACA 16 Alx1_homeodomain_DBD_monomeric_10_1 SELEX - 49211443 49211452 3.0E-06 TCTAATTATA 10 NFKB1_MA0105.1 JASPAR + 49211336 49211346 8.0E-06 GGGGAGTCCCC 11 Rarb_nuclearreceptor_DBD_dimeric_18_1 SELEX + 49211091 49211108 7.0E-06 AGGGTTTAACAGAGGGCA 18 EBF1_MA0154.1 JASPAR - 49212560 49212569 5.0E-06 CCCCAAGGGA 10 MEF2A_MADS_DBD_dimeric_12_1 SELEX + 49210885 49210896 3.0E-06 GTTATAAATAGT 12 MEF2A_MADS_DBD_dimeric_12_1 SELEX + 49211441 49211452 1.0E-05 ATTATAATTAGA 12 CLOCK_bHLH_DBD_dimeric_10_1 SELEX + 49208774 49208783 3.0E-06 TACACGTGTT 10 CLOCK_bHLH_DBD_dimeric_10_1 SELEX - 49208774 49208783 2.0E-06 AACACGTGTA 10 RUNX3_RUNX_full_monomeric_10_1 SELEX - 49212548 49212557 5.0E-06 CAACCACAAA 10 MEF2B_MADS_full_dimeric_12_1 SELEX + 49210885 49210896 5.0E-06 GTTATAAATAGT 12 MEF2B_MADS_full_dimeric_12_1 SELEX - 49210885 49210896 8.0E-06 ACTATTTATAAC 12 IRF1_MA0050.1 JASPAR + 49212009 49212020 5.0E-06 GAAAACCAAACC 12 Rfx3_RFX_DBD_dimeric_16_1 SELEX + 49211020 49211035 7.0E-06 GGTTGCCATGGAAGCC 16 Rfx3_RFX_DBD_dimeric_16_1 SELEX - 49211020 49211035 3.0E-06 GGCTTCCATGGCAACC 16 Rfx3_RFX_DBD_dimeric_16_1 SELEX + 49211407 49211422 3.0E-06 TGTTGCCATAGCATCT 16 Rfx3_RFX_DBD_dimeric_16_1 SELEX - 49211407 49211422 5.0E-06 AGATGCTATGGCAACA 16 MEF2A_MA0052.1 JASPAR - 49210886 49210895 1.0E-06 CTATTTATAA 10 ESR1_MA0112.2 JASPAR - 49211000 49211019 6.0E-06 ATCCCAGATCAGCTTGGCCT 20 SP1_MA0079.2 JASPAR - 49208962 49208971 3.0E-06 CCCCTCCCCC 10 FOXG1_forkhead_DBD_putatively-multimeric_12_1 SELEX - 49212574 49212585 7.0E-06 ATGGCCACAATG 12 CTCF_C2H2_full_monomeric_17_1 SELEX - 49208617 49208633 7.0E-06 GGCGCCCCCTGGAGGCC 17 RARG_nuclearreceptor_DBD_dimeric_17_1 SELEX - 49211982 49211998 7.0E-06 AAGACCACCAGGGGTCA 17 NFKB1_NFAT_DBD_dimeric_13_1 SELEX + 49211335 49211347 8.0E-06 AGGGGAGTCCCCA 13 RFX2_RFX_DBD_dimeric_16_1 SELEX + 49211020 49211035 4.0E-06 GGTTGCCATGGAAGCC 16 RFX2_RFX_DBD_dimeric_16_1 SELEX - 49211020 49211035 4.0E-06 GGCTTCCATGGCAACC 16 RFX2_RFX_DBD_dimeric_16_1 SELEX + 49211407 49211422 5.0E-06 TGTTGCCATAGCATCT 16 RFX2_RFX_DBD_dimeric_16_1 SELEX - 49211407 49211422 4.0E-06 AGATGCTATGGCAACA 16 RFX5_RFX_DBD_dimeric_16_3 SELEX + 49211020 49211035 4.0E-06 GGTTGCCATGGAAGCC 16 RFX5_RFX_DBD_dimeric_16_3 SELEX - 49211020 49211035 2.0E-06 GGCTTCCATGGCAACC 16 RFX5_RFX_DBD_dimeric_16_3 SELEX + 49211407 49211422 2.0E-06 TGTTGCCATAGCATCT 16 RFX5_RFX_DBD_dimeric_16_3 SELEX - 49211407 49211422 3.0E-06 AGATGCTATGGCAACA 16 FEV_MA0156.1 JASPAR - 49210629 49210636 1.0E-05 CAGGAAAT 8 FOXO6_forkhead_DBD_putatively-multimeric_14_1 SELEX + 49208579 49208592 3.0E-06 TGCCCCCACACGAC 14 PLAG1_MA0163.1 JASPAR - 49211054 49211067 6.0E-06 GGGGCCTTAGGGTA 14 Tcfap2a_TFAP_DBD_dimeric_11_1 SELEX + 49208569 49208579 1.0E-05 CGCCCCAGGCT 11 V_MEQ_01_M02049 TRANSFAC - 49212659 49212667 9.0E-06 GACACACAT 9 V_CEBPG_Q6_M00622 TRANSFAC + 49210840 49210852 7.0E-06 CTCATTTCTAAGA 13 V_GEN_INI_B_M00315 TRANSFAC + 49208800 49208807 1.0E-05 CCTCATTT 8 V_GEN_INI_B_M00315 TRANSFAC + 49210839 49210846 1.0E-05 CCTCATTT 8 V_EBF_Q6_M00977 TRANSFAC + 49212559 49212569 1.0E-05 GTCCCTTGGGG 11 V_OSF2_Q6_M00731 TRANSFAC - 49212548 49212555 1.0E-05 ACCACAAA 8 V_BACH2_01_M00490 TRANSFAC - 49212046 49212056 9.0E-06 CATGAATCATC 11 V_SOX40_04_M02908 TRANSFAC + 49211437 49211452 1.0E-06 TCGGATTATAATTAGA 16 V_SOX40_04_M02908 TRANSFAC - 49211437 49211452 0.0E+00 TCTAATTATAATCCGA 16 V_SRY_07_M02813 TRANSFAC + 49211437 49211452 1.0E-06 TCGGATTATAATTAGA 16 V_SRY_07_M02813 TRANSFAC - 49211437 49211452 1.0E-06 TCTAATTATAATCCGA 16 V_ESR1_01_M02261 TRANSFAC - 49211000 49211019 6.0E-06 ATCCCAGATCAGCTTGGCCT 20 V_SREBP2_Q6_M01177 TRANSFAC - 49210860 49210871 5.0E-06 AGGCCATCCCAC 12 V_NF1A_Q6_M02103 TRANSFAC - 49210922 49210937 3.0E-06 CAGGCTCTGAGCCAAG 16 V_EVI1_04_M00081 TRANSFAC + 49211440 49211454 8.0E-06 GATTATAATTAGATC 15 V_AML3_Q6_M01856 TRANSFAC - 49212549 49212556 1.0E-05 AACCACAA 8 V_SP1_Q6_01_M00931 TRANSFAC - 49208994 49209003 4.0E-06 GGGGCGGGGC 10 V_MEF2_02_M00231 TRANSFAC + 49210879 49210900 3.0E-06 CCCAGGGTTATAAATAGTCTGG 22 V_EGR_Q6_M00807 TRANSFAC - 49208577 49208587 6.0E-06 GTGGGGGCAGC 11 V_GATA1_03_M00127 TRANSFAC + 49212095 49212108 3.0E-06 AGGCAGATTAGCAA 14 V_RFX4_03_M02789 TRANSFAC - 49211018 49211032 1.0E-06 TTCCATGGCAACCAT 15 V_EAR2_Q2_M01728 TRANSFAC - 49210992 49211005 7.0E-06 TGGCCTTTGTCCAT 14 V_MAF_Q6_M00648 TRANSFAC + 49209141 49209156 8.0E-06 TCAGGGGAAGTTTGGG 16 V_SP1_03_M02281 TRANSFAC - 49208962 49208971 3.0E-06 CCCCTCCCCC 10 V_DLX2_01_M01468 TRANSFAC + 49211441 49211456 2.0E-06 ATTATAATTAGATCGG 16 V_AP4_Q6_02_M01860 TRANSFAC + 49208910 49208922 7.0E-06 CCAGCTGCGGCAT 13 V_SOX21_03_M02803 TRANSFAC + 49211437 49211452 1.0E-06 TCGGATTATAATTAGA 16 V_CDX_Q5_M00991 TRANSFAC + 49210875 49210892 3.0E-06 GACTCCCAGGGTTATAAA 18 V_NKX62_Q2_M00489 TRANSFAC + 49210885 49210896 1.0E-05 GTTATAAATAGT 12 V_MEF2A_Q6_M02024 TRANSFAC - 49210885 49210894 3.0E-06 TATTTATAAC 10 V_PPARGRXRA_01_M02262 TRANSFAC - 49208762 49208776 7.0E-06 GTATGGCAAGGGGCA 15 V_ZNF219_01_M01122 TRANSFAC - 49208964 49208975 0.0E+00 CGCCCCCCTCCC 12 V_ZNF219_01_M01122 TRANSFAC - 49210899 49210910 1.0E-05 CTCCCCCACCCC 12 V_ZNF219_01_M01122 TRANSFAC + 49210956 49210967 9.0E-06 CACCCCCAACCC 12 V_GEN_INI3_B_M00314 TRANSFAC + 49208800 49208807 1.0E-05 CCTCATTT 8 V_GEN_INI3_B_M00314 TRANSFAC + 49210839 49210846 1.0E-05 CCTCATTT 8 V_FOXA2_02_M02853 TRANSFAC - 49210620 49210634 1.0E-06 GGAAATAATAAAAGG 15 V_LMX1_01_M01409 TRANSFAC - 49211439 49211455 1.0E-06 CGATCTAATTATAATCC 17 V_OCT1_03_M00137 TRANSFAC + 49211441 49211453 3.0E-06 ATTATAATTAGAT 13 V_HNF4_01_B_M00411 TRANSFAC + 49210992 49211006 5.0E-06 ATGGACAAAGGCCAA 15 V_ZBTB7B_04_M02930 TRANSFAC - 49211985 49212001 9.0E-06 AGCAAGACCACCAGGGG 17 V_HES1_Q2_M01009 TRANSFAC + 49211167 49211181 1.0E-06 AAGGCTTGTGGACAG 15 V_AML2_01_M01759 TRANSFAC - 49212549 49212556 1.0E-05 AACCACAA 8 V_RSRFC4_Q2_M00407 TRANSFAC - 49210882 49210898 2.0E-06 AGACTATTTATAACCCT 17 V_RSRFC4_Q2_M00407 TRANSFAC + 49210883 49210899 2.0E-06 GGGTTATAAATAGTCTG 17 V_RSRFC4_Q2_M00407 TRANSFAC - 49211438 49211454 5.0E-06 GATCTAATTATAATCCG 17 V_NFKB_Q6_M00194 TRANSFAC - 49211334 49211347 8.0E-06 TGGGGACTCCCCTC 14 V_SP1_Q6_M00196 TRANSFAC - 49208993 49209005 5.0E-06 GCGGGGCGGGGCT 13 V_CDX2_01_M01449 TRANSFAC - 49210619 49210634 8.0E-06 GGAAATAATAAAAGGT 16 V_MAZ_Q6_01_M02023 TRANSFAC + 49208962 49208975 6.0E-06 GGGGGAGGGGGGCG 14 V_MAZ_Q6_01_M02023 TRANSFAC + 49212614 49212627 7.0E-06 TGGGGAGAGGAGGG 14 V_LXR_DR4_Q3_M00766 TRANSFAC - 49211093 49211108 3.0E-06 TGCCCTCTGTTAAACC 16 V_MEF2_03_M00232 TRANSFAC + 49210879 49210900 9.0E-06 CCCAGGGTTATAAATAGTCTGG 22 V_NFKAPPAB50_01_M00051 TRANSFAC + 49211336 49211345 8.0E-06 GGGGAGTCCC 10 V_RREB1_01_M00257 TRANSFAC + 49210953 49210966 1.0E-05 CCCCACCCCCAACC 14 V_RFX_Q6_M00975 TRANSFAC + 49211406 49211414 4.0E-06 CTGTTGCCA 9 V_EBF1_01_M02267 TRANSFAC - 49212560 49212569 5.0E-06 CCCCAAGGGA 10 V_HNF4A_Q6_01_M02016 TRANSFAC + 49210994 49211008 2.0E-06 GGACAAAGGCCAAGC 15 V_HNF4_DR1_Q3_M00764 TRANSFAC - 49210993 49211005 2.0E-06 TGGCCTTTGTCCA 13 V_CTCF_02_M01259 TRANSFAC + 49208613 49208632 1.0E-06 CAGTGGCCTCCAGGGGGCGC 20 V_SOX11_03_M02795 TRANSFAC + 49210990 49211006 8.0E-06 ATATGGACAAAGGCCAA 17 V_CTCF_01_M01200 TRANSFAC + 49208615 49208634 0.0E+00 GTGGCCTCCAGGGGGCGCCG 20 V_CTCF_01_M01200 TRANSFAC - 49211979 49211998 1.0E-05 AAGACCACCAGGGGTCAGAG 20 V_SP4_Q5_M01273 TRANSFAC + 49208994 49209004 2.0E-06 GCCCCGCCCCG 11 V_HOXA7_02_M01336 TRANSFAC - 49211439 49211455 9.0E-06 CGATCTAATTATAATCC 17 V_TBP_01_M00471 TRANSFAC + 49210887 49210894 4.0E-06 TATAAATA 8 V_DR1_Q3_M00762 TRANSFAC + 49210993 49211005 4.0E-06 TGGACAAAGGCCA 13 V_NCX_01_M00484 TRANSFAC + 49208644 49208653 5.0E-06 CTGTAATTGG 10 V_HNF4_Q6_01_M01031 TRANSFAC + 49210993 49211006 4.0E-06 TGGACAAAGGCCAA 14 V_GEN_INI2_B_M00313 TRANSFAC + 49208800 49208807 1.0E-05 CCTCATTT 8 V_GEN_INI2_B_M00313 TRANSFAC + 49210839 49210846 1.0E-05 CCTCATTT 8 V_LMX1B_01_M01363 TRANSFAC + 49211439 49211455 7.0E-06 GGATTATAATTAGATCG 17 V_MSX1_01_M00394 TRANSFAC + 49208644 49208652 7.0E-06 CTGTAATTG 9 V_ASCL2_04_M02841 TRANSFAC + 49211211 49211226 6.0E-06 CTCTCCCAGCCCCATC 16 V_MTATA_B_M00320 TRANSFAC - 49210879 49210895 8.0E-06 CTATTTATAACCCTGGG 17 V_RSRFC4_01_M00026 TRANSFAC + 49210883 49210898 5.0E-06 GGGTTATAAATAGTCT 16 V_RSRFC4_01_M00026 TRANSFAC - 49210883 49210898 1.0E-06 AGACTATTTATAACCC 16 V_RSRFC4_01_M00026 TRANSFAC + 49211439 49211454 4.0E-06 GGATTATAATTAGATC 16 V_RSRFC4_01_M00026 TRANSFAC - 49211439 49211454 6.0E-06 GATCTAATTATAATCC 16 V_NFAT2_02_M01749 TRANSFAC - 49211022 49211032 8.0E-06 TTCCATGGCAA 11 V_ZFP281_01_M01597 TRANSFAC + 49208961 49208971 3.0E-06 AGGGGGAGGGG 11 V_ZFP281_01_M01597 TRANSFAC - 49210953 49210963 1.0E-06 TGGGGGTGGGG 11 V_MEF3_B_M00319 TRANSFAC - 49204151 49204163 1.0E-05 TGGTCAGGTGTCT 13 V_ZFP281_04_M02831 TRANSFAC - 49208959 49208973 3.0E-06 CCCCCCTCCCCCTCC 15 V_ZFP281_04_M02831 TRANSFAC + 49210951 49210965 7.0E-06 TGCCCCACCCCCAAC 15 V_VDR_Q3_M00444 TRANSFAC + 49204166 49204180 7.0E-06 GGGTGAAAGAGGAGT 15 V_PLAGL1_03_M02786 TRANSFAC - 49208562 49208577 6.0E-06 CCTGGGGCGCCCTTAC 16 V_ARP1_01_M00155 TRANSFAC - 49204730 49204745 3.0E-06 TCAGGCTCTGACCCTA 16 V_ARP1_01_M00155 TRANSFAC + 49211974 49211989 0.0E+00 TGAGGCTCTGACCCCT 16 V_MEF2A_05_M01301 TRANSFAC + 49210884 49210895 6.0E-06 GGTTATAAATAG 12 V_UF1H3BETA_Q6_M01068 TRANSFAC + 49210901 49210914 4.0E-06 GGTGGGGGAGAGGA 14 V_UF1H3BETA_Q6_M01068 TRANSFAC - 49210952 49210965 0.0E+00 GTTGGGGGTGGGGC 14 V_HNF4_01_M00134 TRANSFAC + 49210990 49211008 6.0E-06 ATATGGACAAAGGCCAAGC 19 V_GATA1_02_M00126 TRANSFAC - 49212719 49212732 1.0E-05 TCATAGATAGGGAA 14 V_SP1_Q4_01_M00932 TRANSFAC - 49208993 49209005 9.0E-06 GCGGGGCGGGGCT 13 V_FEV_01_M02269 TRANSFAC - 49210629 49210636 1.0E-05 CAGGAAAT 8 V_BHLHB2_04_M02845 TRANSFAC - 49208767 49208789 8.0E-06 CGACACAACACGTGTATGGCAAG 23 V_HOXA4_Q2_M00640 TRANSFAC + 49211444 49211451 5.0E-06 ATAATTAG 8 V_RFX1_02_M00281 TRANSFAC - 49211406 49211423 1.0E-06 GAGATGCTATGGCAACAG 18 PPARG_RXRA_MA0065.2 JASPAR - 49208762 49208776 7.0E-06 GTATGGCAAGGGGCA 15 V_ESR2_01_M02377 TRANSFAC + 49210998 49211015 1.0E-05 AAAGGCCAAGCTGATCTG 18 V_SOX14_03_M02798 TRANSFAC + 49211437 49211452 1.0E-06 TCGGATTATAATTAGA 16 V_SOX14_03_M02798 TRANSFAC - 49211437 49211452 1.0E-06 TCTAATTATAATCCGA 16

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.