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THOC1 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 9984 THO complex 1 chr18 - 267559 - 273059 268059 Transcription Factor Binding Sites   Download all TFBS in the THOC1 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints SP8_C2H2_DBD_monomeric_12_1 SELEX + 267594 267605 6.0E-06 ACCACTCCCACC 12 POU2F1_POU_DBD_dimeric_14_1 SELEX + 269886 269899 0.0E+00 CATGAATATTCATA 14 POU2F1_POU_DBD_dimeric_14_1 SELEX - 269886 269899 0.0E+00 TATGAATATTCATG 14 SPIC_ETS_full_monomeric_14_1 SELEX - 268876 268889 1.0E-06 AATAAGAGGAAGTT 14 LHX6_homeodomain_full_dimeric_16_1 SELEX + 268626 268641 2.0E-06 TAAGTAGTATTTATTA 16 PDX1_homeodomain_DBD_dimeric_18_1 SELEX - 268625 268642 8.0E-06 ATAATAAATACTACTTAC 18 HINFP1_C2H2_full_monomeric_12_1 SELEX - 267840 267851 5.0E-06 CAGCGTCCGCTC 12 EWSR1-FLI1_MA0149.1 JASPAR + 272834 272851 0.0E+00 GGAGAAAAGGAAGGAATG 18 MEF2A_MADS_DBD_dimeric_12_1 SELEX - 268635 268646 5.0E-06 TTTAATAATAAA 12 RUNX3_RUNX_DBD_dimeric_16_1 SELEX + 267962 267977 8.0E-06 TCACCGTAAACCGCGT 16 RARA_nuclearreceptor_DBD_dimeric_18_2 SELEX - 268586 268603 7.0E-06 GCGGTCATTATTTCAGTG 18 SCRT2_C2H2_DBD_monomeric_13_1 SELEX - 269910 269922 6.0E-06 ATTCAACAAGTTA 13 SPIB_ETS_DBD_monomeric_14_1 SELEX - 268876 268889 0.0E+00 AATAAGAGGAAGTT 14 TEAD1_TEA_full_monomeric_10_1 SELEX - 272844 272853 2.0E-06 CACATTCCTT 10 TFAP2B_TFAP_DBD_dimeric_12_1 SELEX + 267877 267888 6.0E-06 TACCCCAGGGCA 12 POU4F3_POU_DBD_monomeric_16_1 SELEX - 268631 268646 2.0E-06 TTTAATAATAAATACT 16 Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1 SELEX - 268173 268188 7.0E-06 CAACGCCCACCCGAAC 16 RUNX2_RUNX_DBD_dimeric_16_1 SELEX + 267962 267977 1.0E-05 TCACCGTAAACCGCGT 16 RELA_MA0107.1 JASPAR + 268152 268161 5.0E-06 GGGAGTTTCC 10 HOXD8_homeodomain_DBD_monomeric_10_1 SELEX + 272014 272023 9.0E-06 AAAAATTAGC 10 Pou2f2_POU_DBD_dimeric_14_1 SELEX + 269886 269899 0.0E+00 CATGAATATTCATA 14 Pou2f2_POU_DBD_dimeric_14_1 SELEX - 269886 269899 0.0E+00 TATGAATATTCATG 14 POU2F3_POU_DBD_dimeric_12_1 SELEX + 269887 269898 0.0E+00 ATGAATATTCAT 12 POU2F3_POU_DBD_dimeric_12_1 SELEX - 269887 269898 0.0E+00 ATGAATATTCAT 12 SP4_C2H2_full_monomeric_17_1 SELEX + 267591 267607 1.0E-05 GAAACCACTCCCACCCT 17 SP1_C2H2_DBD_monomeric_11_1 SELEX + 267594 267604 7.0E-06 ACCACTCCCAC 11 POU1F1_POU_DBD_monomeric_17_1 SELEX + 269884 269900 2.0E-06 TTCATGAATATTCATAG 17 HESX1_homeodomain_DBD_dimeric_15_1 SELEX + 268625 268639 9.0E-06 GTAAGTAGTATTTAT 15 LHX9_homeodomain_DBD_dimeric_13_1 SELEX - 268626 268638 8.0E-06 TAAATACTACTTA 13 TFAP2C_TFAP_full_dimeric_12_1 SELEX + 267877 267888 9.0E-06 TACCCCAGGGCA 12 POU5F1P1_POU_DBD_monomeric_12_1 SELEX + 269887 269898 0.0E+00 ATGAATATTCAT 12 POU5F1P1_POU_DBD_monomeric_12_1 SELEX - 269887 269898 0.0E+00 ATGAATATTCAT 12 FOXO3_forkhead_full_putatively-multimeric_11_1 SELEX - 268333 268343 5.0E-06 TTTCCCCAAAC 11 TEAD4_TEA_DBD_monomeric_10_1 SELEX - 272844 272853 2.0E-06 CACATTCCTT 10 SPI1_ETS_full_monomeric_14_1 SELEX - 268876 268889 0.0E+00 AATAAGAGGAAGTT 14 POU3F3_POU_DBD_dimeric_12_1 SELEX + 268635 268646 5.0E-06 TTTATTATTAAA 12 POU3F3_POU_DBD_dimeric_12_1 SELEX - 268635 268646 1.0E-06 TTTAATAATAAA 12 POU3F3_POU_DBD_dimeric_12_1 SELEX + 269887 269898 0.0E+00 ATGAATATTCAT 12 POU3F3_POU_DBD_dimeric_12_1 SELEX - 269887 269898 0.0E+00 ATGAATATTCAT 12 POU4F1_POU_DBD_monomeric_14_1 SELEX - 268633 268646 2.0E-06 TTTAATAATAAATA 14 V_NFKAPPAB65_01_M00052 TRANSFAC + 268152 268161 7.0E-06 GGGAGTTTCC 10 V_SPI1_01_M01203 TRANSFAC - 268873 268889 2.0E-06 AATAAGAGGAAGTTACC 17 V_AP1_Q2_M00173 TRANSFAC + 268858 268868 1.0E-06 ACTGACTCAGA 11 V_DBX1_01_M01483 TRANSFAC - 268629 268645 4.0E-06 TTAATAATAAATACTAC 17 V_DBX1_01_M01483 TRANSFAC + 268632 268648 1.0E-06 GTATTTATTATTAAAAG 17 V_FREAC7_01_M00293 TRANSFAC - 268629 268644 9.0E-06 TAATAATAAATACTAC 16 V_NFKB_Q6_01_M00774 TRANSFAC - 268151 268166 2.0E-06 GCTAGGGAAACTCCCA 16 V_MEQCJUN_02_M02048 TRANSFAC + 268063 268073 4.0E-06 GATGACGTCAA 11 V_XFD1_01_M00267 TRANSFAC - 268629 268642 4.0E-06 ATAATAAATACTAC 14 V_BCL6B_03_M02740 TRANSFAC + 267889 267904 5.0E-06 AAATTCGAGTAATTTC 16 V_MYB_03_M02883 TRANSFAC - 268141 268156 3.0E-06 CTCCCAACTGCCAGCT 16 V_BCL6_01_M01183 TRANSFAC - 268617 268632 7.0E-06 CTACTTACATTGCTTT 16 V_BCL6_01_M01183 TRANSFAC - 272006 272021 9.0E-06 TAATTTTTTGTATTTT 16 V_SPIB_02_M02041 TRANSFAC - 268876 268885 8.0E-06 AGAGGAAGTT 10 V_CBF_02_M01080 TRANSFAC - 268594 268609 8.0E-06 ACACTTGCGGTCATTA 16 V_FOXJ2_02_M00423 TRANSFAC + 268549 268562 7.0E-06 GAAATAATACCTGT 14 V_CREB_Q4_01_M00917 TRANSFAC + 268062 268072 0.0E+00 CGATGACGTCA 11 V_TBR2_01_M01774 TRANSFAC + 268604 268612 1.0E-05 AAGTGTGAA 9 V_P50RELAP65_Q5_01_M01224 TRANSFAC + 268153 268164 7.0E-06 GGAGTTTCCCTA 12 V_CMYB_Q5_M01821 TRANSFAC - 268144 268154 8.0E-06 CCCAACTGCCA 11 V_PU1_Q4_M01172 TRANSFAC + 268870 268888 7.0E-06 TCGGGTAACTTCCTCTTAT 19 V_SOX21_03_M02803 TRANSFAC + 268631 268646 5.0E-06 AGTATTTATTATTAAA 16 V_SOX21_03_M02803 TRANSFAC - 268631 268646 4.0E-06 TTTAATAATAAATACT 16 V_SOX21_03_M02803 TRANSFAC + 268634 268649 5.0E-06 ATTTATTATTAAAAGG 16 V_SOX21_03_M02803 TRANSFAC - 268634 268649 5.0E-06 CCTTTTAATAATAAAT 16 V_OCT2_02_M01761 TRANSFAC + 269888 269897 0.0E+00 TGAATATTCA 10 V_OCT2_02_M01761 TRANSFAC - 269888 269897 0.0E+00 TGAATATTCA 10 V_NKX62_Q2_M00489 TRANSFAC - 268631 268642 1.0E-06 ATAATAAATACT 12 V_CDP_04_M01344 TRANSFAC - 268630 268644 6.0E-06 TAATAATAAATACTA 15 V_CDP_04_M01344 TRANSFAC - 268633 268647 5.0E-06 TTTTAATAATAAATA 15 V_HMGA2_01_M01300 TRANSFAC + 267889 267903 8.0E-06 AAATTCGAGTAATTT 15 V_ELF4_04_M02850 TRANSFAC - 268630 268646 8.0E-06 TTTAATAATAAATACTA 17 V_ELF4_04_M02850 TRANSFAC - 268632 268648 3.0E-06 CTTTTAATAATAAATAC 17 V_IPF1_Q4_M00436 TRANSFAC + 268590 268601 1.0E-06 GAAATAATGACC 12 V_PR_Q2_M00960 TRANSFAC - 268527 268536 7.0E-06 GAGAGAACAG 10 V_SPI1_03_M02078 TRANSFAC - 268876 268885 2.0E-06 AGAGGAAGTT 10 V_DBX2_01_M01360 TRANSFAC - 268632 268647 7.0E-06 TTTTAATAATAAATAC 16 V_LMX1_01_M01409 TRANSFAC - 268633 268649 9.0E-06 CCTTTTAATAATAAATA 17 V_OCT1_02_M00136 TRANSFAC - 269884 269898 0.0E+00 ATGAATATTCATGAA 15 V_OCT1_02_M00136 TRANSFAC + 269887 269901 0.0E+00 ATGAATATTCATAGC 15 V_SOX8_04_M02912 TRANSFAC - 269881 269894 1.0E-06 ATATTCATGAAAGT 14 V_RSRFC4_Q2_M00407 TRANSFAC - 268632 268648 1.0E-06 CTTTTAATAATAAATAC 17 V_IRX4_01_M01410 TRANSFAC - 269915 269931 5.0E-06 AACATACATATTCAACA 17 V_AP1_Q4_M00188 TRANSFAC + 268858 268868 9.0E-06 ACTGACTCAGA 11 V_HNF3ALPHA_Q6_M00724 TRANSFAC + 268633 268643 9.0E-06 TATTTATTATT 11 V_STAT5A_02_M00460 TRANSFAC - 272854 272877 4.0E-06 TACCCAGAAACTTCTTACCCAATC 24 V_HNF1_Q6_01_M01011 TRANSFAC - 268630 268650 3.0E-06 ACCTTTTAATAATAAATACTA 21 V_ELF5_01_M01197 TRANSFAC - 268876 268886 1.0E-05 AAGAGGAAGTT 11 V_CUX1_04_M02959 TRANSFAC - 268630 268644 6.0E-06 TAATAATAAATACTA 15 V_CUX1_04_M02959 TRANSFAC - 268633 268647 5.0E-06 TTTTAATAATAAATA 15 V_CMYB_01_M00004 TRANSFAC + 268139 268156 5.0E-06 CGAGCTGGCAGTTGGGAG 18 V_SOX12_04_M02900 TRANSFAC + 272005 272020 3.0E-06 AAAAATACAAAAAATT 16 V_SPIB_01_M01204 TRANSFAC - 268873 268889 0.0E+00 AATAAGAGGAAGTTACC 17 V_NCX_02_M01420 TRANSFAC + 268632 268648 4.0E-06 GTATTTATTATTAAAAG 17 V_ARID3A_04_M02735 TRANSFAC - 268633 268649 7.0E-06 CCTTTTAATAATAAATA 17 V_CREB_Q2_01_M00916 TRANSFAC - 268061 268074 1.0E-06 CTTGACGTCATCGG 14 V_TBP_06_M02814 TRANSFAC + 268629 268644 8.0E-06 GTAGTATTTATTATTA 16 V_TBP_06_M02814 TRANSFAC - 268633 268648 1.0E-05 CTTTTAATAATAAATA 16 V_EVI1_06_M00011 TRANSFAC - 268901 268909 9.0E-06 ACAAGATAC 9 V_ELK1_01_M00007 TRANSFAC - 268873 268888 4.0E-06 ATAAGAGGAAGTTACC 16 V_SOX17_04_M02904 TRANSFAC + 269877 269893 4.0E-06 GACCACTTTCATGAATA 17 V_SOX17_04_M02904 TRANSFAC - 269882 269898 3.0E-06 ATGAATATTCATGAAAG 17 V_BCL6B_04_M02844 TRANSFAC - 267512 267527 4.0E-06 TTCACCACCCCTTAAC 16 V_ELF1_Q6_M00746 TRANSFAC - 268877 268888 0.0E+00 ATAAGAGGAAGT 12 V_CREM_Q6_M01820 TRANSFAC - 268062 268072 6.0E-06 TGACGTCATCG 11 V_VJUN_01_M00036 TRANSFAC + 268061 268076 3.0E-06 CCGATGACGTCAAGCC 16 V_RARA_04_M02891 TRANSFAC + 267926 267941 9.0E-06 AGCGCCGGGTCAGGCC 16 V_MTF1_06_M02882 TRANSFAC + 268544 268557 1.0E-05 AAATAGAAATAATA 14 V_EHF_06_M02745 TRANSFAC - 268875 268889 7.0E-06 AATAAGAGGAAGTTA 15 V_TAL1_01_M01591 TRANSFAC - 272834 272846 0.0E+00 CTTCCTTTTCTCC 13 V_OSR2_04_M02889 TRANSFAC - 268622 268637 3.0E-06 AAATACTACTTACATT 16 V_CACBINDINGPROTEIN_Q6_M00720 TRANSFAC - 267600 267608 8.0E-06 GAGGGTGGG 9 V_CACBINDINGPROTEIN_Q6_M00720 TRANSFAC + 267753 267761 8.0E-06 GAGGGTGGG 9 V_AP1FJ_Q2_M00172 TRANSFAC + 268858 268868 6.0E-06 ACTGACTCAGA 11 V_CAAT_C_M00200 TRANSFAC - 272836 272860 0.0E+00 CCCAATCCACATTCCTTCCTTTTCT 25 V_ATF2_Q5_M01862 TRANSFAC + 268062 268073 3.0E-06 CGATGACGTCAA 12 V_TCF7_04_M02921 TRANSFAC + 268634 268648 1.0E-06 ATTTATTATTAAAAG 15 V_TCFAP2B_03_M02820 TRANSFAC + 267876 267889 8.0E-06 TTACCCCAGGGCAA 14 V_SPIC_02_M02077 TRANSFAC - 268876 268885 1.0E-06 AGAGGAAGTT 10 V_FOX_Q2_M00809 TRANSFAC + 268630 268642 6.0E-06 TAGTATTTATTAT 13 V_RSRFC4_01_M00026 TRANSFAC + 268633 268648 4.0E-06 TATTTATTATTAAAAG 16 V_E47_01_M00002 TRANSFAC - 267637 267651 9.0E-06 GGGGCAGGTGTCTCG 15 V_OSR1_04_M02888 TRANSFAC - 268622 268637 6.0E-06 AAATACTACTTACATT 16 V_SOX8_03_M02808 TRANSFAC + 268632 268648 3.0E-06 GTATTTATTATTAAAAG 17 V_ZFP281_04_M02831 TRANSFAC + 267601 267615 7.0E-06 CCACCCTCCCCCTTC 15 V_EWSR1FLI1_01_M02252 TRANSFAC + 272834 272851 0.0E+00 GGAGAAAAGGAAGGAATG 18 V_EFC_Q6_M00626 TRANSFAC - 268157 268170 1.0E-06 AGTCGCTAGGGAAA 14 V_NMYC_01_M00055 TRANSFAC + 268893 268904 6.0E-06 TCACACGTGTAT 12 V_SATB1_01_M01232 TRANSFAC - 268636 268647 1.0E-06 TTTTAATAATAA 12 V_SOX1_03_M02802 TRANSFAC + 272004 272019 7.0E-06 TAAAAATACAAAAAAT 16 V_CREB_02_M00113 TRANSFAC + 268061 268072 1.0E-05 CCGATGACGTCA 12 V_MOX1_01_M01443 TRANSFAC - 268588 268603 7.0E-06 GCGGTCATTATTTCAG 16 V_PAX4_02_M00377 TRANSFAC + 272013 272023 2.0E-06 AAAAAATTAGC 11 V_PIT1_Q6_M00802 TRANSFAC + 269882 269899 0.0E+00 CTTTCATGAATATTCATA 18 V_ATF_B_M00338 TRANSFAC - 268062 268073 1.0E-06 TTGACGTCATCG 12 V_GLIS2_04_M02863 TRANSFAC - 268633 268646 0.0E+00 TTTAATAATAAATA 14 V_GLIS2_04_M02863 TRANSFAC + 268635 268648 0.0E+00 TTTATTATTAAAAG 14 V_NR2F2_04_M02887 TRANSFAC + 267926 267941 7.0E-06 AGCGCCGGGTCAGGCC 16 V_SPI1_02_M02043 TRANSFAC - 268876 268885 6.0E-06 AGAGGAAGTT 10 V_SPIB_03_M02076 TRANSFAC - 268876 268885 2.0E-06 AGAGGAAGTT 10 V_TCF11_01_M00285 TRANSFAC - 268588 268600 2.0E-06 GTCATTATTTCAG 13

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.