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LGR5 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 8549 leucine-rich repeat containing G protein-coupled receptor 5 chr12 + 71828812 - 71834312 71833812 Transcription Factor Binding Sites   Download all TFBS in the LGR5 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints NFE2_bZIP_DBD_dimeric_11_1 SELEX + 71832901 71832911 9.0E-06 AATGAGTCACT 11 NFE2_bZIP_DBD_dimeric_11_1 SELEX - 71832901 71832911 7.0E-06 AGTGACTCATT 11 FOXJ2_forkhead_DBD_dimeric_13_1 SELEX - 71832970 71832982 3.0E-06 CTAAACAAATACA 13 MESP1_bHLH_DBD_dimeric_10_1 SELEX - 71835140 71835149 9.0E-06 AGCACCTGTT 10 MYF6_bHLH_full_dimeric_10_1 SELEX - 71835974 71835983 9.0E-06 AACAAATGTT 10 ZNF713_C2H2_full_monomeric_17_1 SELEX + 71834470 71834486 8.0E-06 TAGTCGCATTCCACGAA 17 CEBPD_bZIP_DBD_dimeric_10_1 SELEX - 71834959 71834968 0.0E+00 ATTACGCAAT 10 CEBPG_bZIP_full_dimeric_10_1 SELEX - 71834959 71834968 0.0E+00 ATTACGCAAT 10 EWSR1-FLI1_MA0149.1 JASPAR + 71832934 71832951 8.0E-06 GATAGGAAGGCAGCAGTG 18 NFKB1_MA0105.1 JASPAR + 71834899 71834909 9.0E-06 GGGGATTCTCC 11 XBP1_bZIP_DBD_dimeric_12_1 SELEX + 71833510 71833521 5.0E-06 GCTGACGTCACT 12 XBP1_bZIP_DBD_dimeric_12_1 SELEX - 71833510 71833521 9.0E-06 AGTGACGTCAGC 12 RUNX3_RUNX_DBD_dimeric_16_1 SELEX + 71834694 71834709 2.0E-06 CAACCACAAACCCCGA 16 Creb5_bZIP_DBD_dimeric_12_1 SELEX + 71833510 71833521 6.0E-06 GCTGACGTCACT 12 FOXD2_forkhead_DBD_dimeric_14_1 SELEX + 71835970 71835983 3.0E-06 AACAAACATTTGTT 14 FOXD2_forkhead_DBD_dimeric_14_1 SELEX - 71835970 71835983 3.0E-06 AACAAATGTTTGTT 14 Pax4_MA0068.1 JASPAR - 71834945 71834974 7.0E-06 GAAAAAATTACGCAATGAGCCGCCGCCTCA 30 SPIB_ETS_DBD_monomeric_14_1 SELEX + 71834811 71834824 1.0E-06 GGAAAGGGGAAGTG 14 JDP2_bZIP_full_dimeric_12_1 SELEX + 71833510 71833521 6.0E-06 GCTGACGTCACT 12 RUNX3_RUNX_full_monomeric_10_1 SELEX + 71834694 71834703 5.0E-06 CAACCACAAA 10 FOXD3_forkhead_DBD_dimeric_14_1 SELEX + 71835970 71835983 6.0E-06 AACAAACATTTGTT 14 FOXD3_forkhead_DBD_dimeric_14_1 SELEX - 71835970 71835983 7.0E-06 AACAAATGTTTGTT 14 RUNX2_RUNX_DBD_dimeric_16_1 SELEX + 71834694 71834709 3.0E-06 CAACCACAAACCCCGA 16 CEBPB_bZIP_full_dimeric_10_1 SELEX + 71834959 71834968 9.0E-06 ATTGCGTAAT 10 CEBPB_bZIP_full_dimeric_10_1 SELEX - 71834959 71834968 0.0E+00 ATTACGCAAT 10 NFATC1_NFAT_full_dimeric_14_1 SELEX + 71834970 71834983 2.0E-06 TTTTCTGTGGAAAA 14 NFATC1_NFAT_full_dimeric_14_1 SELEX - 71834970 71834983 2.0E-06 TTTTCCACAGAAAA 14 Foxc1_forkhead_DBD_dimeric_11_1 SELEX - 71832972 71832982 7.0E-06 CTAAACAAATA 11 CREB3_bZIP_full_dimeric_14_1 SELEX - 71833509 71833522 2.0E-06 CAGTGACGTCAGCG 14 FOXC2_forkhead_DBD_dimeric_11_1 SELEX - 71832972 71832982 4.0E-06 CTAAACAAATA 11 NFIL3_bZIP_DBD_dimeric_12_1 SELEX + 71834958 71834969 1.0E-05 CATTGCGTAATT 12 VENTX_homeodomain_DBD_dimeric_21_1 SELEX + 71832969 71832989 3.0E-06 CTGTATTTGTTTAGCGATTAG 21 VENTX_homeodomain_DBD_dimeric_21_1 SELEX - 71832971 71832991 1.0E-06 GGCTAATCGCTAAACAAATAC 21 Foxd3_MA0041.1 JASPAR - 71835969 71835980 1.0E-06 AAATGTTTGTTC 12 JDP2_bZIP_full_dimeric_9_1 SELEX + 71832902 71832910 1.0E-05 ATGAGTCAC 9 SPI1_ETS_full_monomeric_14_1 SELEX + 71834811 71834824 1.0E-06 GGAAAGGGGAAGTG 14 RUNX1_MA0002.2 JASPAR - 71834694 71834704 9.0E-06 GTTTGTGGTTG 11 REST_MA0138.2 JASPAR + 71833852 71833872 2.0E-06 TCGGGCACCATGGACACCTCC 21 CEBPE_bZIP_DBD_dimeric_10_1 SELEX - 71834959 71834968 0.0E+00 ATTACGCAAT 10 Sox2_MA0143.1 JASPAR - 71832890 71832904 5.0E-06 CATTTGTTTTTTAAA 15 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 71832970 71832982 4.0E-06 CTAAACAAATACA 13 HNF1A_MA0046.1 JASPAR - 71834780 71834793 2.0E-06 GGTTAAAGATTACA 14 TCF3_bHLH_DBD_dimeric_10_1 SELEX - 71835140 71835149 7.0E-06 AGCACCTGTT 10 V_NFKB_C_M00208 TRANSFAC + 71834899 71834910 6.0E-06 GGGGATTCTCCC 12 V_SPI1_01_M01203 TRANSFAC + 71834811 71834827 2.0E-06 GGAAAGGGGAAGTGGGC 17 V_AP1_Q2_M00173 TRANSFAC - 71832901 71832911 4.0E-06 AGTGACTCATT 11 V_MYOD_Q6_M00184 TRANSFAC - 71835140 71835149 7.0E-06 AGCACCTGTT 10 V_ATF_01_M00017 TRANSFAC + 71833509 71833522 4.0E-06 CGCTGACGTCACTG 14 V_OSF2_Q6_M00731 TRANSFAC + 71834696 71834703 1.0E-05 ACCACAAA 8 V_NRSF_Q4_M01028 TRANSFAC + 71833620 71833638 2.0E-06 CCACTGTCGCCGCTGCAGC 19 V_FOXD3_01_M00130 TRANSFAC - 71835969 71835980 1.0E-06 AAATGTTTGTTC 12 V_COE1_Q6_M01871 TRANSFAC + 71834893 71834906 4.0E-06 TCCCTGGGGGATTC 14 V_AML3_Q6_M01856 TRANSFAC + 71834695 71834702 1.0E-05 AACCACAA 8 V_CREB_Q4_M00178 TRANSFAC - 71833510 71833521 9.0E-06 AGTGACGTCAGC 12 V_HOXA3_01_M00395 TRANSFAC + 71834963 71834971 7.0E-06 CGTAATTTT 9 V_CREB_Q4_01_M00917 TRANSFAC + 71833509 71833519 2.0E-06 CGCTGACGTCA 11 V_CREB_Q4_01_M00917 TRANSFAC - 71833512 71833522 7.0E-06 CAGTGACGTCA 11 V_SRY_02_M00160 TRANSFAC + 71832894 71832905 8.0E-06 AAAAACAAATGA 12 V_NKX25_Q6_M02108 TRANSFAC + 71835958 71835968 0.0E+00 CTCACTTGAAA 11 V_CEBP_01_M00159 TRANSFAC - 71832817 71832829 3.0E-06 TGTTTGCTAACTT 13 V_FOXO3A_Q1_M01137 TRANSFAC + 71832893 71832904 5.0E-06 AAAAAACAAATG 12 V_CEBP_Q2_M00190 TRANSFAC + 71834957 71834970 0.0E+00 TCATTGCGTAATTT 14 V_EAR2_Q2_M01728 TRANSFAC + 71834727 71834740 5.0E-06 TTATCTTTACCTTT 14 V_HNF3_Q6_01_M01012 TRANSFAC - 71835965 71835982 5.0E-06 ACAAATGTTTGTTCTTTC 18 V_MAF_Q6_M00648 TRANSFAC + 71834813 71834828 0.0E+00 AAAGGGGAAGTGGGCT 16 V_JUNDM2_03_M02772 TRANSFAC + 71833508 71833523 6.0E-06 GCGCTGACGTCACTGG 16 V_HFH4_01_M00742 TRANSFAC + 71832969 71832981 0.0E+00 CTGTATTTGTTTA 13 V_PU1_Q4_M01172 TRANSFAC + 71832908 71832926 7.0E-06 CACTTCGACTTCCTCACCC 19 V_PU1_Q4_M01172 TRANSFAC - 71834812 71834830 1.0E-06 TCAGCCCACTTCCCCTTTC 19 V_CDX_Q5_M00991 TRANSFAC - 71832970 71832987 1.0E-05 AATCGCTAAACAAATACA 18 V_AP1_Q6_M00174 TRANSFAC - 71832901 71832911 2.0E-06 AGTGACTCATT 11 V_HES1_Q6_M02011 TRANSFAC - 71833834 71833843 6.0E-06 GCCACGAGCC 10 V_ELF4_04_M02850 TRANSFAC + 71832889 71832905 1.0E-06 TTTTAAAAAACAAATGA 17 V_ZNF219_01_M01122 TRANSFAC - 71833480 71833491 5.0E-06 CACCCCCCGCCC 12 V_SOX7_03_M02807 TRANSFAC + 71832890 71832911 3.0E-06 TTTAAAAAACAAATGAGTCACT 22 V_PR_Q2_M00960 TRANSFAC + 71835965 71835974 5.0E-06 GAAAGAACAA 10 V_SPI1_03_M02078 TRANSFAC + 71834815 71834824 1.0E-05 AGGGGAAGTG 10 V_ZFP105_03_M02827 TRANSFAC + 71832890 71832904 0.0E+00 TTTAAAAAACAAATG 15 V_FKLF_Q5_M01837 TRANSFAC - 71834906 71834915 2.0E-06 GGGGTGGGAG 10 V_HNF3G_Q4_M02015 TRANSFAC - 71835970 71835977 7.0E-06 TGTTTGTT 8 V_RUNX1_01_M02257 TRANSFAC - 71834694 71834704 9.0E-06 GTTTGTGGTTG 11 V_AML2_01_M01759 TRANSFAC + 71834695 71834702 1.0E-05 AACCACAA 8 V_CEBPB_02_M00117 TRANSFAC + 71834957 71834970 7.0E-06 TCATTGCGTAATTT 14 V_AP1_Q4_M00188 TRANSFAC - 71832901 71832911 3.0E-06 AGTGACTCATT 11 V_MAZ_Q6_01_M02023 TRANSFAC + 71834805 71834818 2.0E-06 CGGGGAGGAAAGGG 14 V_HNF3_Q6_M00791 TRANSFAC - 71832970 71832982 1.0E-06 CTAAACAAATACA 13 V_HNF3_Q6_M00791 TRANSFAC + 71835967 71835979 1.0E-06 AAGAACAAACATT 13 V_HNF3ALPHA_Q6_M00724 TRANSFAC + 71832972 71832982 1.0E-06 TATTTGTTTAG 11 V_HNF3ALPHA_Q6_M00724 TRANSFAC - 71835967 71835977 2.0E-06 TGTTTGTTCTT 11 V_EGR1_Q6_M01873 TRANSFAC - 71833704 71833713 7.0E-06 GCGTGGGCGG 10 V_NKX25_Q5_M01043 TRANSFAC + 71835957 71835966 3.0E-06 TCTCACTTGA 10 V_CREBATF_Q6_M00981 TRANSFAC - 71833512 71833520 9.0E-06 GTGACGTCA 9 V_REST_01_M01256 TRANSFAC - 71833855 71833876 0.0E+00 GCCGGGAGGTGTCCATGGTGCC 22 V_SPIB_01_M01204 TRANSFAC + 71834811 71834827 1.0E-05 GGAAAGGGGAAGTGGGC 17 V_ATF3_Q6_M00513 TRANSFAC + 71833509 71833522 1.0E-06 CGCTGACGTCACTG 14 V_VMYB_01_M00003 TRANSFAC - 71835988 71835997 5.0E-06 AGTAACGGAA 10 V_CREB_Q2_01_M00916 TRANSFAC - 71833508 71833521 2.0E-06 AGTGACGTCAGCGC 14 V_CREB_Q2_01_M00916 TRANSFAC + 71833510 71833523 7.0E-06 GCTGACGTCACTGG 14 V_OCT4_02_M01124 TRANSFAC - 71832888 71832902 5.0E-06 TTTGTTTTTTAAAAG 15 V_AP1_Q2_01_M00924 TRANSFAC - 71832898 71832909 5.0E-06 TGACTCATTTGT 12 V_FOXO1_Q5_M01216 TRANSFAC + 71832894 71832902 1.0E-06 AAAAACAAA 9 V_NKX32_02_M01482 TRANSFAC + 71832880 71832896 4.0E-06 CTAAACCACTTTTAAAA 17 V_ELF1_Q6_M00746 TRANSFAC + 71834812 71834823 1.0E-05 GAAAGGGGAAGT 12 V_CREM_Q6_M01820 TRANSFAC - 71833509 71833519 2.0E-06 TGACGTCAGCG 11 V_CREM_Q6_M01820 TRANSFAC + 71833512 71833522 3.0E-06 TGACGTCACTG 11 V_VJUN_01_M00036 TRANSFAC - 71833508 71833523 2.0E-06 CCAGTGACGTCAGCGC 16 V_ATF1_Q6_M00691 TRANSFAC + 71833509 71833519 5.0E-06 CGCTGACGTCA 11 V_CIZ_01_M00734 TRANSFAC - 71834966 71834974 5.0E-06 GAAAAAATT 9 V_CREBP1_Q2_M00179 TRANSFAC + 71833510 71833521 1.0E-06 GCTGACGTCACT 12 V_CREBP1_Q2_M00179 TRANSFAC - 71833510 71833521 5.0E-06 AGTGACGTCAGC 12 V_HNF1_01_M00132 TRANSFAC - 71834779 71834793 1.0E-06 GGTTAAAGATTACAC 15 V_AP1FJ_Q2_M00172 TRANSFAC - 71832901 71832911 3.0E-06 AGTGACTCATT 11 V_T3R_Q6_M00963 TRANSFAC + 71833887 71833895 7.0E-06 CCTGTCCTT 9 V_ATF1_03_M02738 TRANSFAC + 71833508 71833523 4.0E-06 GCGCTGACGTCACTGG 16 V_ATF1_03_M02738 TRANSFAC - 71833508 71833523 7.0E-06 CCAGTGACGTCAGCGC 16 V_ATF2_Q5_M01862 TRANSFAC - 71833511 71833522 1.0E-05 CAGTGACGTCAG 12 V_ZBTB12_03_M02824 TRANSFAC + 71835116 71835132 5.0E-06 GCCAGGTTCTAGGCCAC 17 V_TCF4_Q5_M00671 TRANSFAC + 71834756 71834763 1.0E-05 CCTTTGAA 8 V_FOX_Q2_M00809 TRANSFAC + 71832969 71832981 5.0E-06 CTGTATTTGTTTA 13 V_REST_02_M02256 TRANSFAC + 71833852 71833872 2.0E-06 TCGGGCACCATGGACACCTCC 21 V_NFAT2_02_M01749 TRANSFAC - 71834971 71834981 9.0E-06 TTCCACAGAAA 11 V_NFAT2_02_M01749 TRANSFAC + 71834972 71834982 6.0E-06 TTCTGTGGAAA 11 V_PLZF_02_M01075 TRANSFAC - 71832877 71832905 3.0E-06 TCATTTGTTTTTTAAAAGTGGTTTAGAAT 29 V_SOX2_01_M02246 TRANSFAC - 71832890 71832904 5.0E-06 CATTTGTTTTTTAAA 15 V_SRF_06_M02916 TRANSFAC + 71832888 71832904 3.0E-06 CTTTTAAAAAACAAATG 17 V_SRF_06_M02916 TRANSFAC + 71832889 71832905 1.0E-06 TTTTAAAAAACAAATGA 17 V_SRF_06_M02916 TRANSFAC - 71834659 71834675 2.0E-06 GTTAAAAAAGAAAGAAA 17 V_SRF_06_M02916 TRANSFAC - 71834660 71834676 6.0E-06 CGTTAAAAAAGAAAGAA 17 V_EWSR1FLI1_01_M02252 TRANSFAC + 71832934 71832951 8.0E-06 GATAGGAAGGCAGCAGTG 18 V_ZIC3_04_M02837 TRANSFAC + 71834799 71834813 7.0E-06 TTCCCCCGGGGAGGA 15 V_ZIC1_04_M02835 TRANSFAC + 71834799 71834812 5.0E-06 TTCCCCCGGGGAGG 14 V_HLF_01_M00260 TRANSFAC - 71834959 71834968 3.0E-06 ATTACGCAAT 10 V_FOXO1_01_M00473 TRANSFAC + 71832893 71832902 2.0E-06 AAAAAACAAA 10 V_PAX4_02_M00377 TRANSFAC - 71834963 71834973 1.0E-06 AAAAAATTACG 11 V_CEBP_Q2_01_M00912 TRANSFAC + 71834959 71834970 8.0E-06 ATTGCGTAATTT 12 V_HNF1A_01_M02162 TRANSFAC - 71834780 71834793 2.0E-06 GGTTAAAGATTACA 14 V_ATF_B_M00338 TRANSFAC - 71833509 71833520 1.0E-06 GTGACGTCAGCG 12 V_ATF_B_M00338 TRANSFAC + 71833511 71833522 9.0E-06 CTGACGTCACTG 12 V_RNF96_01_M01199 TRANSFAC + 71834766 71834775 7.0E-06 GCCCGCGGCC 10 V_CEBPE_01_M01772 TRANSFAC + 71834959 71834968 2.0E-06 ATTGCGTAAT 10 V_CEBPE_01_M01772 TRANSFAC - 71834959 71834968 1.0E-06 ATTACGCAAT 10 V_ZIC2_04_M02836 TRANSFAC + 71834799 71834813 7.0E-06 TTCCCCCGGGGAGGA 15 V_CEBPG_Q6_01_M01869 TRANSFAC - 71834958 71834969 6.0E-06 AATTACGCAATG 12 V_PAX4_04_M00380 TRANSFAC + 71832898 71832927 8.0E-06 ACAAATGAGTCACTTCGACTTCCTCACCCC 30 V_SMAD1_01_M01590 TRANSFAC + 71832894 71832905 1.0E-05 AAAAACAAATGA 12 V_SPIB_03_M02076 TRANSFAC - 71832914 71832923 7.0E-06 TGAGGAAGTC 10 V_EGR3_01_M00245 TRANSFAC - 71833704 71833715 9.0E-06 CGGCGTGGGCGG 12 V_NANOG_02_M01247 TRANSFAC + 71832890 71832909 0.0E+00 TTTAAAAAACAAATGAGTCA 20 V_NANOG_02_M01247 TRANSFAC - 71834656 71834675 0.0E+00 GTTAAAAAAGAAAGAAAATA 20 V_OCT4_01_M01125 TRANSFAC - 71832889 71832903 1.0E-05 ATTTGTTTTTTAAAA 15

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