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MYLK2 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 85366 myosin light chain kinase 2 chr20 + 30402177 - 30407677 30407177 Transcription Factor Binding Sites   Download all TFBS in the MYLK2 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints CTCF_MA0139.1 JASPAR + 30410776 30410794 1.0E-06 TTGCCGCTAGGTGGCGCCC 19 RARA_nuclearreceptor_full_dimeric_18_1 SELEX + 30410415 30410432 8.0E-06 TGGGGTGAGATGGGGTCA 18 FOXG1_forkhead_DBD_dimeric_17_1 SELEX - 30410951 30410967 5.0E-06 AAAAACAATCAAACACA 17 MEF2D_MADS_DBD_dimeric_12_1 SELEX + 30410699 30410710 8.0E-06 GCTATTTATAAA 12 MEF2D_MADS_DBD_dimeric_12_1 SELEX - 30410699 30410710 2.0E-06 TTTATAAATAGC 12 ESX1_homeodomain_full_monomeric_10_1 SELEX - 30403594 30403603 5.0E-06 ACCAATTAAA 10 RARG_nuclearreceptor_full_dimeric_17_1 SELEX - 30403572 30403588 9.0E-06 CAGGGGAATTAAGGTCA 17 GLI2_C2H2_DBD_monomeric_14_1 SELEX - 30410831 30410844 1.0E-06 GACCACCCATGGCG 14 MEF2A_MADS_DBD_dimeric_12_1 SELEX + 30410699 30410710 7.0E-06 GCTATTTATAAA 12 MEF2A_MADS_DBD_dimeric_12_1 SELEX - 30410699 30410710 1.0E-06 TTTATAAATAGC 12 MSX1_homeodomain_full_monomeric_8_1 SELEX - 30403595 30403602 7.0E-06 CCAATTAA 8 MEOX2_homeodomain_DBD_dimeric_14_1 SELEX - 30410290 30410303 6.0E-06 CTAATCATCAATGA 14 MSX2_homeodomain_DBD_monomeric_8_1 SELEX - 30403595 30403602 7.0E-06 CCAATTAA 8 GBX2_homeodomain_full_monomeric_10_1 SELEX - 30403594 30403603 2.0E-06 ACCAATTAAA 10 MEF2B_MADS_full_dimeric_12_1 SELEX - 30410699 30410710 4.0E-06 TTTATAAATAGC 12 HMX3_homeodomain_DBD_monomeric_11_1 SELEX - 30403593 30403603 2.0E-06 ACCAATTAAAC 11 RUNX2_RUNX_DBD_dimeric_18_1 SELEX - 30411838 30411855 7.0E-06 GAACCACACAGACCACGT 18 MEF2A_MA0052.1 JASPAR + 30410700 30410709 1.0E-06 CTATTTATAA 10 RAX_homeodomain_DBD_monomeric_10_1 SELEX - 30403594 30403603 6.0E-06 ACCAATTAAA 10 FOXO4_forkhead_DBD_putatively-multimeric_12_1 SELEX + 30410765 30410776 5.0E-06 GTTCCCCACACT 12 CTCF_C2H2_full_monomeric_17_1 SELEX - 30410777 30410793 0.0E+00 GGCGCCACCTAGCGGCA 17 SP1_C2H2_DBD_monomeric_11_1 SELEX - 30410410 30410420 7.0E-06 ACCCCACCCCC 11 PBX1_MA0070.1 JASPAR - 30410955 30410966 4.0E-06 AAAACAATCAAA 12 BSX_homeodomain_DBD_monomeric_8_1 SELEX - 30403595 30403602 7.0E-06 CCAATTAA 8 GSX2_homeodomain_DBD_monomeric_10_1 SELEX - 30403594 30403603 2.0E-06 ACCAATTAAA 10 Msx3_homeodomain_DBD_monomeric_8_1 SELEX - 30403595 30403602 7.0E-06 CCAATTAA 8 ERF_ETS_DBD_monomeric_10_1 SELEX - 30403617 30403626 9.0E-06 ACAGGAAGTG 10 FOXO3_forkhead_full_putatively-multimeric_11_1 SELEX + 30410765 30410775 1.0E-06 GTTCCCCACAC 11 HMX2_homeodomain_DBD_monomeric_11_1 SELEX - 30403593 30403603 1.0E-06 ACCAATTAAAC 11 LBX2_homeodomain_DBD_monomeric_10_1 SELEX - 30403594 30403603 1.0E-06 ACCAATTAAA 10 GSX1_homeodomain_DBD_monomeric_10_1 SELEX - 30403594 30403603 6.0E-06 ACCAATTAAA 10 TP53_MA0106.1 JASPAR - 30403322 30403341 4.0E-06 AAGGACCTGTTCGGAGAAGT 20 FOXO6_forkhead_DBD_putatively-multimeric_14_1 SELEX + 30410765 30410778 6.0E-06 GTTCCCCACACTTG 14 FOXO1_forkhead_DBD_putatively-multimeric_12_1 SELEX + 30410765 30410776 1.0E-06 GTTCCCCACACT 12 RORA_1_MA0071.1 JASPAR - 30403572 30403581 6.0E-06 ATTAAGGTCA 10 Nobox_MA0125.1 JASPAR + 30403596 30403603 7.0E-06 TAATTGGT 8 MNX1_homeodomain_DBD_monomeric_10_1 SELEX - 30403594 30403603 5.0E-06 ACCAATTAAA 10 RREB1_MA0073.1 JASPAR - 30410410 30410429 7.0E-06 CCCCATCTCACCCCACCCCC 20 HMX1_homeodomain_DBD_monomeric_11_1 SELEX - 30403593 30403603 2.0E-06 ACCAATTAAAC 11 RUNX3_RUNX_DBD_dimeric_18_1 SELEX - 30411838 30411855 7.0E-06 GAACCACACAGACCACGT 18 V_NFAT_Q4_01_M00935 TRANSFAC - 30403277 30403286 5.0E-06 ATGGAAAATC 10 V_TGIF_01_M00418 TRANSFAC + 30411540 30411550 5.0E-06 AGCTGTCACAT 11 V_MSX3_01_M01341 TRANSFAC - 30403592 30403607 1.0E-06 CAAGACCAATTAAACC 16 V_NFKB_Q6_01_M00774 TRANSFAC - 30403274 30403289 6.0E-06 GTGATGGAAAATCCAA 16 V_CDX2_Q5_01_M01659 TRANSFAC - 30410700 30410710 5.0E-06 TTTATAAATAG 11 V_APOLYA_B_M00310 TRANSFAC - 30410652 30410666 5.0E-06 ATCAAACGGCCTTTG 15 V_APOLYA_B_M00310 TRANSFAC + 30411620 30411634 3.0E-06 AATACACAGCATTTT 15 V_ZFP410_04_M02936 TRANSFAC + 30410602 30410618 1.0E-06 CCGCCCCGCCCCGAAAT 17 V_SMAD3_Q6_01_M01888 TRANSFAC - 30411633 30411645 1.0E-06 AGACAGACAGAAA 13 V_YY1_02_M00069 TRANSFAC + 30411800 30411819 9.0E-06 CCAGGGCCATCCTCCCTACA 20 V_MAX_Q6_M01830 TRANSFAC - 30411836 30411847 5.0E-06 CAGACCACGTGC 12 V_HMGIY_Q3_M01010 TRANSFAC + 30411625 30411639 4.0E-06 ACAGCATTTTTCTGT 15 V_GM397_03_M02760 TRANSFAC - 30411551 30411567 8.0E-06 ACTGAGTGCACATCAGC 17 V_ETS_B_M00340 TRANSFAC - 30403360 30403373 2.0E-06 GAGAGGAAATCAGT 14 V_ETS_B_M00340 TRANSFAC - 30403559 30403572 8.0E-06 AGCAGGATGCAATT 14 V_MMEF2_Q6_M00405 TRANSFAC - 30410698 30410713 2.0E-06 CTCTTTATAAATAGCA 16 V_LMAF_Q2_M01139 TRANSFAC - 30403568 30403576 6.0E-06 GGTCAGCAG 9 V_SP1_Q6_01_M00931 TRANSFAC - 30410604 30410613 4.0E-06 GGGGCGGGGC 10 V_MEF2_02_M00231 TRANSFAC - 30410695 30410716 6.0E-06 AACCTCTTTATAAATAGCAAGA 22 V_GLI1_01_M01702 TRANSFAC - 30410834 30410844 1.0E-06 GACCACCCATG 11 V_IRF3_05_M02767 TRANSFAC - 30410712 30410725 5.0E-06 AGGAATGGAAACCT 14 V_HFH4_01_M00742 TRANSFAC + 30410954 30410966 7.0E-06 GTTTGATTGTTTT 13 V_SP1_02_M01303 TRANSFAC + 30410411 30410421 5.0E-06 GGGGTGGGGTG 11 V_NFAT2_01_M01748 TRANSFAC - 30403278 30403286 2.0E-06 ATGGAAAAT 9 V_MEF2A_Q6_M02024 TRANSFAC + 30410701 30410710 2.0E-06 TATTTATAAA 10 V_REX1_01_M01695 TRANSFAC + 30411868 30411877 7.0E-06 TCAGCCATTG 10 V_ETS_Q4_M00771 TRANSFAC + 30403614 30403625 6.0E-06 CCCCACTTCCTG 12 V_GLI3_02_M01704 TRANSFAC - 30410834 30410844 1.0E-06 GACCACCCATG 11 V_ZNF219_01_M01122 TRANSFAC + 30410454 30410465 3.0E-06 CACCCCCCTGCC 12 V_TGIF_02_M01346 TRANSFAC + 30407037 30407053 7.0E-06 AAGAGTGACAGGTGGCG 17 V_ZIC3_01_M00450 TRANSFAC + 30410836 30410844 6.0E-06 TGGGTGGTC 9 V_ZFP105_03_M02827 TRANSFAC - 30410694 30410708 1.0E-05 TATAAATAGCAAGAG 15 V_MYCMAX_01_M00118 TRANSFAC + 30411833 30411846 9.0E-06 TGTGCACGTGGTCT 14 V_MYCMAX_01_M00118 TRANSFAC - 30411833 30411846 9.0E-06 AGACCACGTGCACA 14 V_HOXB13_01_M01467 TRANSFAC - 30403590 30403605 5.0E-06 AGACCAATTAAACCCG 16 V_CMYC_01_M01145 TRANSFAC + 30411834 30411845 9.0E-06 GTGCACGTGGTC 12 V_CMYC_01_M01145 TRANSFAC - 30411834 30411845 3.0E-06 GACCACGTGCAC 12 V_E12_Q6_M00693 TRANSFAC + 30407043 30407053 8.0E-06 GACAGGTGGCG 11 V_ZBP89_Q4_M01816 TRANSFAC + 30411748 30411757 4.0E-06 CCCTCCCCCA 10 V_CEBPB_02_M00117 TRANSFAC + 30403259 30403272 1.0E-06 TTGTTGCTCAACTC 14 V_RSRFC4_Q2_M00407 TRANSFAC - 30410696 30410712 1.0E-06 TCTTTATAAATAGCAAG 17 V_PXRRXR_02_M01153 TRANSFAC - 30403506 30403513 1.0E-05 AGAGTTCA 8 V_AMEF2_Q6_M00403 TRANSFAC - 30410696 30410713 8.0E-06 CTCTTTATAAATAGCAAG 18 V_HOXB9_01_M01426 TRANSFAC - 30403590 30403605 4.0E-06 AGACCAATTAAACCCG 16 V_MAZ_Q6_01_M02023 TRANSFAC - 30407088 30407101 3.0E-06 GACGGAGGAGAGGA 14 V_MEF2_03_M00232 TRANSFAC - 30410695 30410716 2.0E-06 AACCTCTTTATAAATAGCAAGA 22 V_PBX1_01_M00096 TRANSFAC - 30410956 30410964 7.0E-06 AACAATCAA 9 V_TEL2_Q6_M00678 TRANSFAC + 30403616 30403625 6.0E-06 CCACTTCCTG 10 V_XFD2_01_M00268 TRANSFAC - 30410697 30410710 5.0E-06 TTTATAAATAGCAA 14 V_ZIC1_01_M00448 TRANSFAC + 30410836 30410844 6.0E-06 TGGGTGGTC 9 V_MEF2_Q6_01_M00941 TRANSFAC + 30410698 30410709 1.0E-06 TGCTATTTATAA 12 V_CETS1P54_01_M00032 TRANSFAC - 30403617 30403626 9.0E-06 ACAGGAAGTG 10 V_SRF_Q5_02_M01007 TRANSFAC + 30403333 30403351 6.0E-06 CAGGTCCTTTTAAAGCCTC 19 V_TBP_06_M02814 TRANSFAC - 30410697 30410712 5.0E-06 TCTTTATAAATAGCAA 16 V_TGIF1_01_M03111 TRANSFAC + 30407037 30407053 7.0E-06 AAGAGTGACAGGTGGCG 17 V_CTCF_02_M01259 TRANSFAC + 30410773 30410792 1.0E-06 CACTTGCCGCTAGGTGGCGC 20 V_CTCF_01_M01200 TRANSFAC + 30410775 30410794 1.0E-06 CTTGCCGCTAGGTGGCGCCC 20 V_AP1_Q2_01_M00924 TRANSFAC + 30411702 30411713 7.0E-06 TGACTCAGTCTT 12 V_TFIII_Q6_M00706 TRANSFAC - 30411728 30411736 6.0E-06 AGAGGGAGG 9 V_NEUROD_02_M01288 TRANSFAC + 30410944 30410955 3.0E-06 TAGCTGCTGTGT 12 V_GLI3_01_M01596 TRANSFAC + 30410835 30410845 5.0E-06 ATGGGTGGTCT 11 V_SP4_Q5_M01273 TRANSFAC + 30410604 30410614 2.0E-06 GCCCCGCCCCG 11 V_MYOD_Q6_02_M02100 TRANSFAC + 30411539 30411547 4.0E-06 CAGCTGTCA 9 V_TBP_01_M00471 TRANSFAC - 30410701 30410708 4.0E-06 TATAAATA 8 V_GLI2_01_M01703 TRANSFAC - 30410834 30410844 1.0E-06 GACCACCCATG 11 V_GABPBETA_Q3_M01876 TRANSFAC - 30403616 30403626 5.0E-06 ACAGGAAGTGG 11 V_PKNOX2_01_M01411 TRANSFAC - 30407038 30407053 7.0E-06 CGCCACCTGTCACTCT 16 V_CACBINDINGPROTEIN_Q6_M00720 TRANSFAC + 30410872 30410880 8.0E-06 GAGGGTGGG 9 V_BARHL1_01_M01332 TRANSFAC - 30403592 30403607 2.0E-06 CAAGACCAATTAAACC 16 V_MSX2_01_M01393 TRANSFAC - 30403591 30403607 5.0E-06 CAAGACCAATTAAACCC 17 V_HDX_01_M01333 TRANSFAC - 30403357 30403373 7.0E-06 GAGAGGAAATCAGTTCA 17 V_PARP_Q3_M01211 TRANSFAC + 30411615 30411624 8.0E-06 TAGGAAATAC 10 V_STAT6_02_M00500 TRANSFAC + 30403363 30403370 1.0E-05 GATTTCCT 8 V_RSRFC4_01_M00026 TRANSFAC + 30410697 30410712 2.0E-06 TTGCTATTTATAAAGA 16 V_RSRFC4_01_M00026 TRANSFAC - 30410697 30410712 6.0E-06 TCTTTATAAATAGCAA 16 V_T3RBETA_Q6_01_M02119 TRANSFAC - 30403571 30403587 1.0E-06 AGGGGAATTAAGGTCAG 17 V_T3RBETA_Q6_01_M02119 TRANSFAC + 30410417 30410433 1.0E-06 GGGTGAGATGGGGTCAG 17 V_ETS1_B_M00339 TRANSFAC - 30403612 30403626 4.0E-06 ACAGGAAGTGGGGCA 15 V_ZFP281_01_M01597 TRANSFAC + 30410409 30410419 1.0E-06 TGGGGGTGGGG 11 V_SREBP1_02_M00221 TRANSFAC - 30410414 30410424 7.0E-06 TCTCACCCCAC 11 V_FOXO1_01_M00473 TRANSFAC - 30410959 30410968 5.0E-06 CAAAAACAAT 10 V_BARHL2_01_M01446 TRANSFAC - 30403592 30403607 1.0E-06 CAAGACCAATTAAACC 16 V_MEF2A_05_M01301 TRANSFAC + 30410698 30410709 1.0E-06 TGCTATTTATAA 12 V_FOXO4_01_M00472 TRANSFAC - 30410957 30410967 5.0E-06 AAAAACAATCA 11 V_PBX1_Q3_M02028 TRANSFAC - 30410662 30410670 6.0E-06 ATAAATCAA 9 V_ZIC2_01_M00449 TRANSFAC + 30410836 30410844 6.0E-06 TGGGTGGTC 9 V_TR4_03_M01782 TRANSFAC - 30407018 30407030 5.0E-06 AGTTCAGAGGACA 13

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.