Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

TUSC3 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 7991 tumor suppressor candidate 3 chr8 + 15392595 - 15398095 15397595 Transcription Factor Binding Sites   Download all TFBS in the TUSC3 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints TBX20_TBX_full_monomeric_11_1 SELEX - 15398310 15398320 7.0E-06 AAGGTGTGAGG 11 NFE2_bZIP_DBD_dimeric_11_1 SELEX + 15397271 15397281 2.0E-06 AATGAGTCATT 11 NFE2_bZIP_DBD_dimeric_11_1 SELEX - 15397271 15397281 1.0E-06 AATGACTCATT 11 CTCF_MA0139.1 JASPAR + 15399806 15399824 8.0E-06 AAGCCTCCAGGTGGCAGAC 19 HOXD12_homeodomain_DBD_monomeric_9_1 SELEX - 15399790 15399798 2.0E-06 CTAATAAAA 9 SP8_C2H2_DBD_monomeric_12_1 SELEX + 15397703 15397714 0.0E+00 GCCACGCCCACT 12 FOXJ2_forkhead_DBD_dimeric_13_1 SELEX - 15395737 15395749 1.0E-06 CTAAACATAAAAA 13 SP3_C2H2_DBD_monomeric_11_1 SELEX + 15397703 15397713 1.0E-06 GCCACGCCCAC 11 SPIC_ETS_full_monomeric_14_1 SELEX + 15398067 15398080 7.0E-06 AGAAAAAGGAGGTA 14 KLF16_C2H2_DBD_monomeric_11_1 SELEX + 15397703 15397713 3.0E-06 GCCACGCCCAC 11 EMX2_homeodomain_DBD_dimeric_14_1 SELEX + 15395713 15395726 0.0E+00 CAATTAGGTAATTT 14 EMX2_homeodomain_DBD_dimeric_14_1 SELEX - 15395713 15395726 0.0E+00 AAATTACCTAATTG 14 KLF14_C2H2_DBD_monomeric_14_1 SELEX + 15397702 15397715 1.0E-06 CGCCACGCCCACTT 14 TBP_MA0108.2 JASPAR - 15397207 15397221 5.0E-06 ATATAAAAACGAATA 15 Tp73_p53l_DBD_dimeric_18_1 SELEX + 15394631 15394648 6.0E-06 AACATGTTACAACCTGCT 18 Tp73_p53l_DBD_dimeric_18_1 SELEX - 15394631 15394648 3.0E-06 AGCAGGTTGTAACATGTT 18 MEF2A_MADS_DBD_dimeric_12_1 SELEX - 15395415 15395426 4.0E-06 CATAAAAATAGC 12 HOMEZ_HOMEZ_DBD_monomer-or-dimer_12_1 SELEX - 15397205 15397216 4.0E-06 AAAACGAATAGA 12 FOXD2_forkhead_DBD_dimeric_14_1 SELEX - 15399841 15399854 3.0E-06 AAGAAACATTTACA 14 Klf4_MA0039.2 JASPAR - 15397703 15397712 1.0E-05 TGGGCGTGGC 10 BARHL2_homeodomain_full_dimeric_16_1 SELEX + 15399843 15399858 4.0E-06 TAAATGTTTCTTATCA 16 TEAD1_TEA_full_monomeric_10_1 SELEX + 15394727 15394736 7.0E-06 AACATTCCTT 10 MEF2B_MADS_full_dimeric_12_1 SELEX - 15395415 15395426 1.0E-05 CATAAAAATAGC 12 Barhl1_homeodomain_DBD_dimeric_16_1 SELEX + 15399843 15399858 4.0E-06 TAAATGTTTCTTATCA 16 RFX2_RFX_DBD_dimeric_15_1 SELEX + 15398134 15398148 1.0E-06 CGTTGCCAGGCAGCC 15 RFX2_RFX_DBD_dimeric_15_1 SELEX + 15398155 15398169 0.0E+00 TGTTGCTAGGCAGCC 15 HOXD11_homeodomain_DBD_monomeric_10_2 SELEX - 15399790 15399799 5.0E-06 GCTAATAAAA 10 FOXD3_forkhead_DBD_dimeric_14_1 SELEX - 15399841 15399854 9.0E-06 AAGAAACATTTACA 14 HOXC12_homeodomain_DBD_monomeric_9_1 SELEX - 15399790 15399798 7.0E-06 CTAATAAAA 9 MEF2A_MA0052.1 JASPAR + 15395416 15395425 5.0E-06 CTATTTTTAT 10 HOXD13_homeodomain_DBD_monomeric_10_1 SELEX - 15399789 15399798 2.0E-06 CTAATAAAAC 10 RFX3_RFX_DBD_dimeric_15_1 SELEX + 15398134 15398148 2.0E-06 CGTTGCCAGGCAGCC 15 RFX3_RFX_DBD_dimeric_15_1 SELEX + 15398155 15398169 0.0E+00 TGTTGCTAGGCAGCC 15 SP4_C2H2_full_monomeric_17_1 SELEX + 15397700 15397716 0.0E+00 CTCGCCACGCCCACTTC 17 SOX9_HMG_full_dimeric_16_3 SELEX - 15395615 15395630 6.0E-06 TTGTATAACCAGTCAT 16 SP1_C2H2_DBD_monomeric_11_1 SELEX + 15397703 15397713 4.0E-06 GCCACGCCCAC 11 HOXA13_homeodomain_full_monomeric_10_1 SELEX - 15399789 15399798 2.0E-06 CTAATAAAAC 10 RFX4_RFX_DBD_dimeric_15_1 SELEX + 15398134 15398148 4.0E-06 CGTTGCCAGGCAGCC 15 RFX4_RFX_DBD_dimeric_15_1 SELEX + 15398155 15398169 3.0E-06 TGTTGCTAGGCAGCC 15 VENTX_homeodomain_DBD_dimeric_21_1 SELEX - 15397206 15397226 1.0E-06 TTTTAATATAAAAACGAATAG 21 EN1_homeodomain_full_dimeric_14_1 SELEX - 15395562 15395575 6.0E-06 TAATAAGTCAGTTA 14 EN1_homeodomain_full_dimeric_14_1 SELEX + 15395665 15395678 1.0E-05 TAAATGCCTTATTA 14 EN1_homeodomain_full_dimeric_14_1 SELEX - 15395665 15395678 7.0E-06 TAATAAGGCATTTA 14 EN1_homeodomain_full_dimeric_14_1 SELEX + 15395713 15395726 9.0E-06 CAATTAGGTAATTT 14 EN1_homeodomain_full_dimeric_14_1 SELEX - 15395713 15395726 8.0E-06 AAATTACCTAATTG 14 JDP2_bZIP_full_dimeric_9_1 SELEX + 15397272 15397280 4.0E-06 ATGAGTCAT 9 JDP2_bZIP_full_dimeric_9_1 SELEX - 15397272 15397280 2.0E-06 ATGACTCAT 9 Meis2_MEIS_DBD_dimeric_12_1 SELEX - 15398312 15398323 1.0E-05 TGAAAGGTGTGA 12 TBX20_TBX_DBD_monomeric_15_1 SELEX - 15398309 15398323 9.0E-06 TGAAAGGTGTGAGGT 15 HOXC13_homeodomain_DBD_monomeric_10_1 SELEX - 15399789 15399798 2.0E-06 CTAATAAAAC 10 GBX2_homeodomain_DBD_dimeric_14_1 SELEX + 15395562 15395575 6.0E-06 TAACTGACTTATTA 14 GBX2_homeodomain_DBD_dimeric_14_1 SELEX - 15395562 15395575 7.0E-06 TAATAAGTCAGTTA 14 GBX2_homeodomain_DBD_dimeric_14_1 SELEX + 15395665 15395678 7.0E-06 TAAATGCCTTATTA 14 GBX2_homeodomain_DBD_dimeric_14_1 SELEX - 15395665 15395678 8.0E-06 TAATAAGGCATTTA 14 SPDEF_ETS_full_monomeric_11_1 SELEX + 15397756 15397766 9.0E-06 AACCGGATGCT 11 TEAD4_TEA_DBD_monomeric_10_1 SELEX + 15394727 15394736 4.0E-06 AACATTCCTT 10 THRB_nuclearreceptor_DBD_dimeric_19_1 SELEX + 15393351 15393369 1.0E-06 TTGACCTGAATAAAGTGAT 19 THRB_nuclearreceptor_DBD_dimeric_19_1 SELEX - 15393351 15393369 5.0E-06 ATCACTTTATTCAGGTCAA 19 EMX1_homeodomain_DBD_dimeric_14_1 SELEX + 15395713 15395726 1.0E-06 CAATTAGGTAATTT 14 EMX1_homeodomain_DBD_dimeric_14_1 SELEX - 15395713 15395726 0.0E+00 AAATTACCTAATTG 14 POU3F3_POU_DBD_dimeric_12_1 SELEX - 15397214 15397225 1.0E-05 TTTAATATAAAA 12 ELF5_MA0136.1 JASPAR + 15395722 15395730 5.0E-06 AATTTCCTT 9 Hoxa11_homeodomain_DBD_monomeric_11_1 SELEX - 15399789 15399799 7.0E-06 GCTAATAAAAC 11 CDX2_homeodomain_DBD_monomeric_9_1 SELEX - 15399790 15399798 9.0E-06 CTAATAAAA 9 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 15395735 15395747 7.0E-06 AAACATAAAAACA 13 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 15395737 15395749 1.0E-06 CTAAACATAAAAA 13 TP63_p53l_DBD_dimeric_18_1 SELEX + 15394631 15394648 3.0E-06 AACATGTTACAACCTGCT 18 TP63_p53l_DBD_dimeric_18_1 SELEX - 15394631 15394648 1.0E-06 AGCAGGTTGTAACATGTT 18 HOXB13_homeodomain_DBD_monomeric_10_1 SELEX - 15399789 15399798 2.0E-06 CTAATAAAAC 10 FOXJ2_forkhead_DBD_dimeric_14_1 SELEX + 15395599 15395612 8.0E-06 ACAAACAGCCAACA 14 V_AP1_Q2_M00173 TRANSFAC - 15397271 15397281 6.0E-06 AATGACTCATT 11 V_STAT3_01_M00225 TRANSFAC + 15398230 15398250 2.0E-06 GGGCGTTTCCGGGACGTGGAG 21 V_DBX1_01_M01483 TRANSFAC + 15397214 15397230 6.0E-06 TTTTATATTAAAAGTAG 17 V_AML_Q6_M00769 TRANSFAC - 15395645 15395659 3.0E-06 ATGGCTGTGGTCTGA 15 V_AR_02_M00953 TRANSFAC + 15398273 15398299 3.0E-06 AACGACGGCAAAGCGTGTTCTTGACTG 27 V_HMGIY_Q3_M01010 TRANSFAC + 15395717 15395731 5.0E-06 TAGGTAATTTCCTTA 15 V_MEF2_02_M00231 TRANSFAC - 15395411 15395432 2.0E-06 TTGAGACATAAAAATAGCCTCA 22 V_FOXO3A_Q1_M01137 TRANSFAC - 15395731 15395742 4.0E-06 TAAAAACAAAGT 12 V_HNF3_Q6_01_M01012 TRANSFAC + 15395738 15395755 1.0E-06 TTTTATGTTTAGTCTATT 18 V_HOXA2_01_M01402 TRANSFAC - 15395715 15395730 4.0E-06 AAGGAAATTACCTAAT 16 V_NERF_Q2_M00531 TRANSFAC - 15397705 15397722 1.0E-06 GGGCAGGAAGTGGGCGTG 18 V_PRX2_Q2_M02115 TRANSFAC + 15397216 15397224 4.0E-06 TTATATTAA 9 V_HOXD13_01_M01404 TRANSFAC - 15399786 15399801 3.0E-06 TGGCTAATAAAACCAT 16 V_K2B_01_M01348 TRANSFAC + 15395708 15395724 2.0E-06 GTAGCCAATTAGGTAAT 17 V_LDSPOLYA_B_M00317 TRANSFAC + 15398506 15398521 2.0E-06 AGAGTGTGTTTTAAGT 16 V_LHX8_01_M01440 TRANSFAC - 15395707 15395723 9.0E-06 TTACCTAATTGGCTACA 17 V_BARBIE_01_M00238 TRANSFAC + 15398067 15398081 8.0E-06 AGAAAAAGGAGGTAG 15 V_AP1_Q6_M00174 TRANSFAC - 15397271 15397281 0.0E+00 AATGACTCATT 11 V_WT1_Q6_01_M02036 TRANSFAC - 15398109 15398118 4.0E-06 CGCCCCCGCC 10 V_ETV7_01_M02071 TRANSFAC - 15398233 15398242 1.0E-05 CCCGGAAACG 10 V_HOXA6_01_M01392 TRANSFAC - 15395715 15395730 1.0E-06 AAGGAAATTACCTAAT 16 V_POU3F2_01_M00463 TRANSFAC - 15395379 15395392 9.0E-06 ACAAGTAAATTTAT 14 V_POLY_C_M00212 TRANSFAC - 15399780 15399797 0.0E+00 TAATAAAACCATGGTCTC 18 V_TATA_01_M00252 TRANSFAC - 15397207 15397221 5.0E-06 ATATAAAAACGAATA 15 V_XFD3_01_M00269 TRANSFAC - 15395739 15395752 7.0E-06 AGACTAAACATAAA 14 V_SP4_03_M02810 TRANSFAC + 15397702 15397718 9.0E-06 CGCCACGCCCACTTCCT 17 V_KROX_Q6_M00982 TRANSFAC - 15398107 15398120 1.0E-06 CCCGCCCCCGCCCA 14 V_CEBPD_Q6_M00621 TRANSFAC - 15395714 15395725 7.0E-06 AATTACCTAATT 12 V_P53_03_M01651 TRANSFAC + 15394630 15394649 8.0E-06 AAACATGTTACAACCTGCTC 20 V_P53_03_M01651 TRANSFAC - 15394630 15394649 8.0E-06 GAGCAGGTTGTAACATGTTT 20 V_RSRFC4_Q2_M00407 TRANSFAC + 15397218 15397234 9.0E-06 ATATTAAAAGTAGCTAG 17 V_IRX4_01_M01410 TRANSFAC + 15394627 15394643 7.0E-06 AAGAAACATGTTACAAC 17 V_AP1_Q6_01_M00925 TRANSFAC - 15397272 15397280 4.0E-06 ATGACTCAT 9 V_AP1_Q4_M00188 TRANSFAC - 15397271 15397281 8.0E-06 AATGACTCATT 11 V_IRF3_Q3_M01279 TRANSFAC - 15395466 15395478 1.0E-06 GTATTTTTGCTTT 13 V_EGR1_Q6_M01873 TRANSFAC + 15398110 15398119 4.0E-06 GCGGGGGCGG 10 V_LHX2_01_M01325 TRANSFAC - 15395707 15395723 7.0E-06 TTACCTAATTGGCTACA 17 V_MEF2_03_M00232 TRANSFAC - 15397213 15397234 1.0E-05 CTAGCTACTTTTAATATAAAAA 22 V_JUNDM2_04_M02876 TRANSFAC + 15397268 15397283 3.0E-06 CTGAATGAGTCATTGA 16 V_JUNDM2_04_M02876 TRANSFAC - 15397269 15397284 9.0E-06 TTCAATGACTCATTCA 16 V_NFE4_Q5_M02105 TRANSFAC + 15397696 15397707 2.0E-06 CTCCCTCGCCAC 12 V_HBP1_03_M02762 TRANSFAC + 15397277 15397292 9.0E-06 TCATTGAATGAAGTGG 16 V_MEF2_04_M00233 TRANSFAC - 15395735 15395756 7.0E-06 CAATAGACTAAACATAAAAACA 22 V_TEL2_Q6_M00678 TRANSFAC + 15397710 15397719 6.0E-06 CCACTTCCTG 10 V_AP1_C_M00199 TRANSFAC + 15397272 15397280 8.0E-06 ATGAGTCAT 9 V_HFH1_01_M00129 TRANSFAC - 15394722 15394733 5.0E-06 GAATGTTTAGGT 12 V_MEF2_Q6_01_M00941 TRANSFAC + 15395414 15395425 0.0E+00 GGCTATTTTTAT 12 V_CDC5_01_M00478 TRANSFAC - 15397216 15397227 5.0E-06 CTTTTAATATAA 12 V_AP1_01_M00517 TRANSFAC + 15397270 15397282 3.0E-06 GAATGAGTCATTG 13 V_TBP_06_M02814 TRANSFAC + 15397211 15397226 3.0E-06 CGTTTTTATATTAAAA 16 V_TBP_06_M02814 TRANSFAC - 15397211 15397226 2.0E-06 TTTTAATATAAAAACG 16 V_TBP_06_M02814 TRANSFAC + 15397213 15397228 7.0E-06 TTTTTATATTAAAAGT 16 V_TBP_06_M02814 TRANSFAC - 15397213 15397228 4.0E-06 ACTTTTAATATAAAAA 16 V_CTCF_02_M01259 TRANSFAC + 15399803 15399822 4.0E-06 ATGAAGCCTCCAGGTGGCAG 20 V_CTCF_01_M01200 TRANSFAC + 15399805 15399824 4.0E-06 GAAGCCTCCAGGTGGCAGAC 20 V_TBX5_01_M01019 TRANSFAC - 15398310 15398321 7.0E-06 AAAGGTGTGAGG 12 V_IRX5_01_M01472 TRANSFAC - 15394626 15394642 7.0E-06 TTGTAACATGTTTCTTA 17 V_IRX5_01_M01472 TRANSFAC + 15394627 15394643 6.0E-06 AAGAAACATGTTACAAC 17 V_FOXO1_Q5_M01216 TRANSFAC - 15395733 15395741 1.0E-06 AAAAACAAA 9 V_HOXD9_Q2_M01834 TRANSFAC - 15395420 15395429 4.0E-06 AGACATAAAA 10 V_HOXD9_Q2_M01834 TRANSFAC - 15395738 15395747 2.0E-06 AAACATAAAA 10 V_AP1_Q4_01_M00926 TRANSFAC + 15397273 15397280 1.0E-05 TGAGTCAT 8 V_S8_01_M00099 TRANSFAC + 15395481 15395496 4.0E-06 AAGAGGCAATTAGCCT 16 V_CACBINDINGPROTEIN_Q6_M00720 TRANSFAC + 15398213 15398221 8.0E-06 GAGGGTGGG 9 V_FOXJ3_06_M02855 TRANSFAC - 15395730 15395746 1.0E-05 AACATAAAAACAAAGTA 17 V_TCF7_04_M02921 TRANSFAC + 15395568 15395582 3.0E-06 ACTTATTAAAACCCA 15 V_TCF7_04_M02921 TRANSFAC - 15397212 15397226 4.0E-06 TTTTAATATAAAAAC 15 V_FRA1_Q5_M01267 TRANSFAC + 15397273 15397280 1.0E-05 TGAGTCAT 8 V_BBX_03_M02739 TRANSFAC + 15397277 15397291 2.0E-06 TCATTGAATGAAGTG 15 V_TBX5_Q5_M01044 TRANSFAC + 15398311 15398320 1.0E-06 CTCACACCTT 10 V_IRX2_01_M01405 TRANSFAC - 15394626 15394642 4.0E-06 TTGTAACATGTTTCTTA 17 V_IRX2_01_M01405 TRANSFAC + 15394627 15394643 5.0E-06 AAGAAACATGTTACAAC 17 V_P63_01_M01656 TRANSFAC + 15394630 15394649 1.0E-06 AAACATGTTACAACCTGCTC 20 V_P63_01_M01656 TRANSFAC - 15394630 15394649 1.0E-06 GAGCAGGTTGTAACATGTTT 20 V_DMRT2_01_M01147 TRANSFAC - 15399843 15399858 5.0E-06 TGATAAGAAACATTTA 16 V_MYF6_03_M02781 TRANSFAC + 15397330 15397345 7.0E-06 AAGGAACAGTTGTGAA 16 V_SOX14_04_M02901 TRANSFAC + 15398389 15398405 1.0E-06 GTGTTGGATGTGAAAAT 17 V_HOMEZ_01_M01429 TRANSFAC + 15397204 15397220 3.0E-06 GTCTATTCGTTTTTATA 17 V_FOXO1_01_M00473 TRANSFAC - 15395733 15395742 9.0E-06 TAAAAACAAA 10 V_ALX3_01_M01355 TRANSFAC - 15395707 15395723 7.0E-06 TTACCTAATTGGCTACA 17 V_MEF2A_05_M01301 TRANSFAC + 15395414 15395425 1.0E-06 GGCTATTTTTAT 12 V_LHX4_01_M01421 TRANSFAC - 15395707 15395723 8.0E-06 TTACCTAATTGGCTACA 17 V_AP2ALPHA_02_M01045 TRANSFAC - 15398222 15398236 3.0E-06 AACGCCCCAGGGCCT 15 V_ELF5_04_M02241 TRANSFAC + 15395722 15395730 5.0E-06 AATTTCCTT 9 V_OG2_02_M01441 TRANSFAC + 15395708 15395724 6.0E-06 GTAGCCAATTAGGTAAT 17 V_ALX3_02_M02943 TRANSFAC - 15395707 15395723 7.0E-06 TTACCTAATTGGCTACA 17 V_BRCA_01_M01082 TRANSFAC - 15398491 15398498 1.0E-05 TTCTGTTG 8 V_GLIS2_04_M02863 TRANSFAC - 15397212 15397225 7.0E-06 TTTAATATAAAAAC 14 V_MIF1_01_M00279 TRANSFAC + 15398154 15398171 7.0E-06 GTGTTGCTAGGCAGCCTG 18 V_HOXB5_01_M01319 TRANSFAC - 15395715 15395730 5.0E-06 AAGGAAATTACCTAAT 16 V_HOX13_02_M01452 TRANSFAC - 15395715 15395730 1.0E-05 AAGGAAATTACCTAAT 16

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.