Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

IRX1 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 79192 iroquois homeobox 1 chr5 + 3591167 - 3596667 3596167 Transcription Factor Binding Sites   Download all TFBS in the IRX1 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints Foxk1_forkhead_DBD_putatively-multimeric_11_1 SELEX - 3595942 3595952 7.0E-06 CAGACACAATT 11 VSX2_homeodomain_DBD_monomeric_8_1 SELEX - 3597796 3597803 5.0E-06 CTAATTAT 8 Myc_MA0147.1 JASPAR - 3595818 3595827 7.0E-06 AGCACGTGGT 10 ZNF713_C2H2_full_monomeric_17_1 SELEX - 3599048 3599064 1.0E-06 TAGAAAAGTTCCACAAA 17 LHX6_homeodomain_full_dimeric_16_1 SELEX - 3594345 3594360 9.0E-06 TAATTACTAATAACCA 16 Foxj3_forkhead_DBD_putatively-multimeric_11_1 SELEX - 3595943 3595953 9.0E-06 TCAGACACAAT 11 SOX8_HMG_DBD_dimeric_16_1 SELEX - 3594226 3594241 1.0E-05 TACAACCTCCAGGGTT 16 MAX_bHLH_DBD_dimeric_10_1 SELEX + 3595818 3595827 1.0E-06 ACCACGTGCT 10 ZNF232_C2H2_full_monomeric_19_1 SELEX - 3598591 3598609 6.0E-06 CTGTAAAATATTAACGCAA 19 Tcfap2a_TFAP_DBD_dimeric_13_1 SELEX - 3600999 3601011 8.0E-06 AGCCCTGGGGGCG 13 Pax4_MA0068.1 JASPAR - 3600590 3600619 9.0E-06 GAAAAACGTCACCCCTCACCCCACCACCAC 30 HOXB5_homeodomain_DBD_monomeric_10_1 SELEX + 3597795 3597804 5.0E-06 AATAATTAGA 10 FOXK1_forkhead_DBD_putatively-multimeric_10_1 SELEX - 3595943 3595952 8.0E-06 CAGACACAAT 10 LEF1_HMG_DBD_monomeric_15_1 SELEX + 3598497 3598511 7.0E-06 CCAGATCAAAGTCAA 15 IRF1_MA0050.1 JASPAR + 3598503 3598514 1.0E-05 CAAAGTCAAACT 12 HNF1A_homeodomain_full_dimeric_15_1 SELEX + 3598594 3598608 3.0E-06 CGTTAATATTTTACA 15 HNF1A_homeodomain_full_dimeric_15_1 SELEX - 3598594 3598608 2.0E-06 TGTAAAATATTAACG 15 HOXB2_homeodomain_DBD_monomeric_10_1 SELEX + 3597795 3597804 1.0E-05 AATAATTAGA 10 HOXD8_homeodomain_DBD_monomeric_10_1 SELEX + 3597795 3597804 4.0E-06 AATAATTAGA 10 MNT_bHLH_DBD_dimeric_10_1 SELEX + 3595818 3595827 2.0E-06 ACCACGTGCT 10 SP1_MA0079.2 JASPAR + 3600996 3601005 7.0E-06 CCCCGCCCCC 10 SP1_C2H2_DBD_monomeric_11_1 SELEX + 3600995 3601005 4.0E-06 ACCCCGCCCCC 11 HNF1B_homeodomain_full_dimeric_13_1 SELEX + 3598595 3598607 3.0E-06 GTTAATATTTTAC 13 HNF1B_homeodomain_full_dimeric_13_1 SELEX - 3598595 3598607 1.0E-06 GTAAAATATTAAC 13 HESX1_homeodomain_DBD_dimeric_15_1 SELEX + 3594347 3594361 1.0E-06 GTTATTAGTAATTAC 15 LHX9_homeodomain_DBD_dimeric_13_1 SELEX - 3594348 3594360 1.0E-06 TAATTACTAATAA 13 HOXB3_homeodomain_DBD_monomeric_10_1 SELEX + 3597795 3597804 6.0E-06 AATAATTAGA 10 Evi1_MA0029.1 JASPAR + 3598284 3598297 9.0E-06 GTCAAAAGATAAAA 14 HNF1B_homeodomain_full_dimeric_15_1 SELEX + 3598594 3598608 4.0E-06 CGTTAATATTTTACA 15 HNF1B_homeodomain_full_dimeric_15_1 SELEX - 3598594 3598608 2.0E-06 TGTAAAATATTAACG 15 Sox2_MA0143.1 JASPAR - 3598277 3598291 8.0E-06 CTTTTGACTTCCAAA 15 TGIF1_MEIS_DBD_dimeric_12_1 SELEX + 3595676 3595687 8.0E-06 AGACAGCTGTAA 12 RREB1_MA0073.1 JASPAR - 3600587 3600606 5.0E-06 CCTCACCCCACCACCACCCC 20 HMX1_homeodomain_DBD_monomeric_11_1 SELEX - 3598775 3598785 6.0E-06 AGCAATTTAAA 11 Zfx_MA0146.1 JASPAR - 3596640 3596653 3.0E-06 GGGGCCGCGGCCTC 14 Zfx_MA0146.1 JASPAR + 3599007 3599020 3.0E-06 GGGGCCGCGGCCTC 14 V_DBX1_01_M01483 TRANSFAC - 3594348 3594364 3.0E-06 GTAGTAATTACTAATAA 17 V_FOXP3_Q4_M00992 TRANSFAC + 3594299 3594315 9.0E-06 GACAATCTGACTCAGAG 17 V_LEF1_04_M02774 TRANSFAC - 3598496 3598512 8.0E-06 TTTGACTTTGATCTGGA 17 V_AR_02_M00953 TRANSFAC - 3597244 3597270 7.0E-06 AGCCAAGGGACACTGTTTTCTTTAATC 27 V_ATF5_01_M01295 TRANSFAC + 3599275 3599285 5.0E-06 TCTCTCCCTTT 11 V_GATA2_02_M00348 TRANSFAC + 3598288 3598297 8.0E-06 AAAGATAAAA 10 V_NRSF_Q4_M01028 TRANSFAC + 3594655 3594673 1.0E-05 GCGGAGTCCGGTGTGCTGG 19 V_OBOX1_01_M01450 TRANSFAC + 3597237 3597253 9.0E-06 AATGGAGGATTAAAGAA 17 V_ZFX_01_M01593 TRANSFAC - 3595894 3595909 2.0E-06 GCGCAGGCCCCGCCCC 16 V_DLX3_01_M01400 TRANSFAC + 3597791 3597807 2.0E-06 CCAAAATAATTAGAAAA 17 V_HP1SITEFACTOR_Q6_M00725 TRANSFAC + 3598598 3598609 0.0E+00 AATATTTTACAG 12 V_GATA3_03_M00351 TRANSFAC + 3598288 3598297 4.0E-06 AAAGATAAAA 10 V_STAT_Q6_M00777 TRANSFAC + 3597604 3597616 7.0E-06 AACTTTTCTTGTA 13 V_HOXA13_02_M01297 TRANSFAC - 3598817 3598825 3.0E-06 AAATAAACC 9 V_SP1_Q6_01_M00931 TRANSFAC + 3595894 3595903 4.0E-06 GGGGCGGGGC 10 V_SP1_Q6_01_M00931 TRANSFAC - 3600995 3601004 7.0E-06 GGGGCGGGGT 10 V_DR4_Q2_M00965 TRANSFAC - 3596851 3596867 9.0E-06 CGACCTGCAGGAACCCC 17 V_EVI1_02_M00079 TRANSFAC + 3599752 3599762 8.0E-06 TGACAAGATCG 11 V_HOXA4_01_M01370 TRANSFAC - 3597792 3597808 9.0E-06 CTTTTCTAATTATTTTG 17 V_SOX11_04_M02899 TRANSFAC + 3598294 3598307 6.0E-06 AAAATTGTATTTGA 14 V_HOXC4_01_M01369 TRANSFAC + 3597792 3597808 7.0E-06 CAAAATAATTAGAAAAG 17 V_MAF_Q6_M00648 TRANSFAC - 3599289 3599304 7.0E-06 AGGAGGGAAGTGGAGA 16 V_SP1_03_M02281 TRANSFAC + 3600996 3601005 7.0E-06 CCCCGCCCCC 10 V_HOXA2_01_M01402 TRANSFAC + 3597793 3597808 3.0E-06 AAAATAATTAGAAAAG 16 V_DLX2_01_M01468 TRANSFAC + 3597793 3597808 0.0E+00 AAAATAATTAGAAAAG 16 V_HOXC6_01_M01406 TRANSFAC + 3597792 3597808 7.0E-06 CAAAATAATTAGAAAAG 17 V_OCTAMER_02_M01477 TRANSFAC + 3597791 3597807 5.0E-06 CCAAAATAATTAGAAAA 17 V_OCTAMER_02_M01477 TRANSFAC - 3597792 3597808 7.0E-06 CTTTTCTAATTATTTTG 17 V_LHX3_01_M01471 TRANSFAC + 3597792 3597808 3.0E-06 CAAAATAATTAGAAAAG 17 V_SP1_02_M01303 TRANSFAC - 3600994 3601004 8.0E-06 GGGGCGGGGTC 11 V_COUPTF_Q6_M01036 TRANSFAC + 3597906 3597928 7.0E-06 TCTTCTGGTCTTTACAACTTTCT 23 V_CMYC_02_M01154 TRANSFAC - 3595817 3595828 8.0E-06 GAGCACGTGGTG 12 V_SOX21_03_M02803 TRANSFAC + 3598293 3598308 9.0E-06 TAAAATTGTATTTGAA 16 V_SOX21_03_M02803 TRANSFAC - 3598293 3598308 1.0E-05 TTCAAATACAATTTTA 16 V_BRN2_01_M00145 TRANSFAC - 3598818 3598833 2.0E-06 CTCAATCAAAATAAAC 16 V_PAX6_02_M01391 TRANSFAC - 3597791 3597806 8.0E-06 TTTCTAATTATTTTGG 16 V_PAX7_01_M01339 TRANSFAC + 3597792 3597808 7.0E-06 CAAAATAATTAGAAAAG 17 V_VSX1_01_M01335 TRANSFAC + 3597792 3597808 6.0E-06 CAAAATAATTAGAAAAG 17 V_NKX62_Q2_M00489 TRANSFAC + 3597793 3597804 2.0E-06 AAAATAATTAGA 12 V_HES1_Q6_M02011 TRANSFAC + 3600029 3600038 6.0E-06 GCCACGAGCC 10 V_MYC_01_M02250 TRANSFAC - 3595818 3595827 7.0E-06 AGCACGTGGT 10 V_ELF4_04_M02850 TRANSFAC - 3595620 3595636 8.0E-06 TTTTTAACAAAAACAAC 17 V_ELF4_04_M02850 TRANSFAC - 3598818 3598834 9.0E-06 GCTCAATCAAAATAAAC 17 V_ZNF219_01_M01122 TRANSFAC - 3600834 3600845 1.0E-06 CTCCCCCCTCCC 12 V_GC_01_M00255 TRANSFAC + 3595892 3595905 4.0E-06 CAGGGGCGGGGCCT 14 V_GC_01_M00255 TRANSFAC - 3600993 3601006 3.0E-06 TGGGGGCGGGGTCG 14 V_TCF3_04_M02816 TRANSFAC + 3598496 3598512 2.0E-06 TCCAGATCAAAGTCAAA 17 V_HOXA6_01_M01392 TRANSFAC + 3597793 3597808 5.0E-06 AAAATAATTAGAAAAG 16 V_EN1_02_M01365 TRANSFAC + 3597791 3597806 7.0E-06 CCAAAATAATTAGAAA 16 V_DBX2_01_M01360 TRANSFAC - 3597793 3597808 7.0E-06 CTTTTCTAATTATTTT 16 V_LMX1_01_M01409 TRANSFAC + 3597792 3597808 3.0E-06 CAAAATAATTAGAAAAG 17 V_ZFP105_03_M02827 TRANSFAC - 3595621 3595635 9.0E-06 TTTTAACAAAAACAA 15 V_ZFP105_03_M02827 TRANSFAC + 3597786 3597800 9.0E-06 TACAACCAAAATAAT 15 V_HNF1_Q6_M00790 TRANSFAC + 3598593 3598610 1.0E-05 GCGTTAATATTTTACAGG 18 V_CMYC_01_M01145 TRANSFAC + 3595817 3595828 1.0E-06 CACCACGTGCTC 12 V_TEF_Q6_M00672 TRANSFAC - 3598591 3598602 9.0E-06 ATATTAACGCAA 12 V_SOX7_04_M02911 TRANSFAC + 3595937 3595958 1.0E-06 CTTCAAATTGTGTCTGAAAGCC 22 V_SOX7_04_M02911 TRANSFAC - 3597785 3597806 8.0E-06 TTTCTAATTATTTTGGTTGTAA 22 V_SP4_03_M02810 TRANSFAC - 3595870 3595886 5.0E-06 CCTCCCGCCCCCTCCCT 17 V_ZBP89_Q4_M01816 TRANSFAC - 3600838 3600847 6.0E-06 TCCTCCCCCC 10 V_SP1_Q6_M00196 TRANSFAC + 3595892 3595904 4.0E-06 CAGGGGCGGGGCC 13 V_SP1_Q6_M00196 TRANSFAC - 3600994 3601006 2.0E-06 TGGGGGCGGGGTC 13 MYC_MAX_MA0059.1 JASPAR - 3595818 3595828 1.0E-06 GAGCACGTGGT 11 V_MAZ_Q6_01_M02023 TRANSFAC + 3600827 3600840 1.0E-06 GGCGGTGGGGAGGG 14 V_HNF3_Q6_M00791 TRANSFAC - 3600802 3600814 9.0E-06 AAAAGCAAACAGC 13 V_GSH2_01_M01326 TRANSFAC + 3597793 3597808 5.0E-06 AAAATAATTAGAAAAG 16 V_HNF1_Q6_01_M01011 TRANSFAC - 3598591 3598611 5.0E-06 GCCTGTAAAATATTAACGCAA 21 V_OBOX2_01_M01364 TRANSFAC + 3597237 3597253 7.0E-06 AATGGAGGATTAAAGAA 17 V_SREBP_Q6_M01168 TRANSFAC - 3600594 3600608 9.0E-06 CCCCTCACCCCACCA 15 V_SOX18_03_M02801 TRANSFAC + 3598293 3598308 1.0E-05 TAAAATTGTATTTGAA 16 V_HOX13_01_M00023 TRANSFAC + 3597879 3597908 1.0E-06 AGTCACCAAACTAATTAGTCCAAGAAATCT 30 V_OCT1_08_M01354 TRANSFAC + 3597791 3597806 5.0E-06 CCAAAATAATTAGAAA 16 V_OCT1_08_M01354 TRANSFAC - 3597793 3597808 4.0E-06 CTTTTCTAATTATTTT 16 V_SP1SP3_Q4_M01219 TRANSFAC - 3595872 3595882 1.0E-06 CCGCCCCCTCC 11 V_MUSCLE_INI_B_M00321 TRANSFAC + 3595748 3595768 1.0E-06 CCGGGCCCACACCCCGCCGCC 21 V_GRE_C_M00205 TRANSFAC + 3597721 3597736 0.0E+00 TTTACAAGGTGTCCTT 16 V_TCF7_03_M02817 TRANSFAC + 3598496 3598512 2.0E-06 TCCAGATCAAAGTCAAA 17 V_PBX1_05_M01967 TRANSFAC - 3595916 3595929 1.0E-06 TTTGATTGGCATCC 14 V_KLF7_03_M02773 TRANSFAC + 3600992 3601007 1.0E-06 TCGACCCCGCCCCCAG 16 V_NCX_02_M01420 TRANSFAC - 3594348 3594364 2.0E-06 GTAGTAATTACTAATAA 17 V_HNF4A_Q6_01_M02016 TRANSFAC + 3598500 3598514 6.0E-06 GATCAAAGTCAAACT 15 V_ARID3A_04_M02735 TRANSFAC - 3598820 3598836 1.0E-05 GGGCTCAATCAAAATAA 17 V_SP1_01_M00008 TRANSFAC - 3600995 3601004 3.0E-06 GGGGCGGGGT 10 V_OCT4_02_M01124 TRANSFAC - 3594290 3594304 0.0E+00 ATTGTCTTGCTAGTC 15 V_LIM1_01_M01418 TRANSFAC + 3597792 3597808 1.0E-06 CAAAATAATTAGAAAAG 17 V_SP4_Q5_M01273 TRANSFAC - 3595893 3595903 8.0E-06 GCCCCGCCCCT 11 V_DLX7_01_M01486 TRANSFAC + 3597791 3597807 1.0E-06 CCAAAATAATTAGAAAA 17 V_MYOD_Q6_02_M02100 TRANSFAC - 3595676 3595684 8.0E-06 CAGCTGTCT 9 V_LEF1_Q2_01_M01022 TRANSFAC + 3598500 3598509 8.0E-06 GATCAAAGTC 10 V_OBOX2_02_M03064 TRANSFAC + 3597237 3597253 7.0E-06 AATGGAGGATTAAAGAA 17 V_BRN4_01_M01473 TRANSFAC + 3597790 3597806 9.0E-06 ACCAAAATAATTAGAAA 17 V_IPF1_05_M01255 TRANSFAC - 3598302 3598313 8.0E-06 AGACATTCAAAT 12 V_FOXL1_02_M02857 TRANSFAC - 3598816 3598831 3.0E-06 CAATCAAAATAAACCA 16 V_GATA3_02_M00350 TRANSFAC + 3598288 3598297 3.0E-06 AAAGATAAAA 10 V_MYOGNF1_01_M00056 TRANSFAC - 3594618 3594646 5.0E-06 CAGCAGCGCACTCTGGCGTCTTCTCGGCT 29 V_PITX1_01_M01484 TRANSFAC + 3597237 3597253 8.0E-06 AATGGAGGATTAAAGAA 17 V_GATA6_01_M00462 TRANSFAC + 3598288 3598297 3.0E-06 AAAGATAAAA 10 V_MSX1_02_M01412 TRANSFAC - 3597793 3597808 9.0E-06 CTTTTCTAATTATTTT 16 V_LMX1B_01_M01363 TRANSFAC - 3597792 3597808 3.0E-06 CTTTTCTAATTATTTTG 17 V_FPM315_01_M01587 TRANSFAC + 3600839 3600850 0.0E+00 GGGGGAGGAGGA 12 V_FOX_Q2_M00809 TRANSFAC + 3598814 3598826 1.0E-06 GATGGTTTATTTT 13 V_ZFP281_01_M01597 TRANSFAC - 3600996 3601006 6.0E-06 TGGGGGCGGGG 11 V_HOXC5_01_M01454 TRANSFAC + 3597792 3597808 3.0E-06 CAAAATAATTAGAAAAG 17 V_CHX10_01_M00437 TRANSFAC + 3597794 3597807 5.0E-06 AAATAATTAGAAAA 14 V_SOX2_01_M02246 TRANSFAC - 3598277 3598291 8.0E-06 CTTTTGACTTCCAAA 15 V_ZFP281_04_M02831 TRANSFAC - 3600830 3600844 8.0E-06 TCCCCCCTCCCCACC 15 V_ZFP281_04_M02831 TRANSFAC - 3600836 3600850 4.0E-06 TCCTCCTCCCCCCTC 15 V_SRF_06_M02916 TRANSFAC - 3595619 3595635 8.0E-06 TTTTAACAAAAACAACT 17 V_SRF_06_M02916 TRANSFAC - 3595620 3595636 9.0E-06 TTTTTAACAAAAACAAC 17 V_VAX1_01_M01397 TRANSFAC + 3597793 3597808 3.0E-06 AAAATAATTAGAAAAG 16 V_HOXD8_01_M01432 TRANSFAC - 3594348 3594364 7.0E-06 GTAGTAATTACTAATAA 17 V_RFX3_05_M02892 TRANSFAC - 3594141 3594163 9.0E-06 GTGGATTCTTGGTGACACAAATC 23 V_MOX1_01_M01443 TRANSFAC + 3597793 3597808 2.0E-06 AAAATAATTAGAAAAG 16 V_PAX4_02_M00377 TRANSFAC + 3597794 3597804 6.0E-06 AAATAATTAGA 11 V_BSX_01_M01442 TRANSFAC + 3597793 3597808 7.0E-06 AAAATAATTAGAAAAG 16 V_SOX12_03_M02796 TRANSFAC + 3595624 3595637 1.0E-05 TTTTTGTTAAAAAG 14 V_HOXD3_01_M01338 TRANSFAC - 3597793 3597808 6.0E-06 CTTTTCTAATTATTTT 16 V_SP1_Q2_01_M00933 TRANSFAC - 3595893 3595902 7.0E-06 CCCCGCCCCT 10 V_SP1_Q2_01_M00933 TRANSFAC + 3600996 3601005 4.0E-06 CCCCGCCCCC 10 V_LHX4_01_M01421 TRANSFAC - 3597791 3597807 3.0E-06 TTTTCTAATTATTTTGG 17 V_LHX5_01_M01353 TRANSFAC + 3597792 3597808 4.0E-06 CAAAATAATTAGAAAAG 17 V_CMAF_01_M01070 TRANSFAC + 3598777 3598795 9.0E-06 TAAATTGCTGGCGGATTTA 19 V_SOX5_07_M02909 TRANSFAC + 3598291 3598307 2.0E-06 GATAAAATTGTATTTGA 17 V_SP1_Q4_01_M00932 TRANSFAC + 3595892 3595904 3.0E-06 CAGGGGCGGGGCC 13 V_SP1_Q4_01_M00932 TRANSFAC - 3600994 3601006 5.0E-06 TGGGGGCGGGGTC 13 V_TAACC_B_M00331 TRANSFAC + 3597793 3597815 4.0E-06 AAAATAATTAGAAAAGCGCAAAG 23 V_OBOX5_01_M01381 TRANSFAC + 3597238 3597254 8.0E-06 ATGGAGGATTAAAGAAA 17 V_OBOX3_02_M03065 TRANSFAC + 3597237 3597253 9.0E-06 AATGGAGGATTAAAGAA 17 V_SREBP1_Q5_M01173 TRANSFAC - 3600594 3600608 1.0E-06 CCCCTCACCCCACCA 15 V_OBOX6_06_M03067 TRANSFAC - 3597238 3597254 8.0E-06 TTTCTTTAATCCTCCAT 17 V_OBOX3_01_M01466 TRANSFAC + 3597237 3597253 9.0E-06 AATGGAGGATTAAAGAA 17 V_HOXA4_Q2_M00640 TRANSFAC + 3597796 3597803 5.0E-06 ATAATTAG 8 V_HOXB5_01_M01319 TRANSFAC + 3597793 3597808 7.0E-06 AAAATAATTAGAAAAG 16 V_SOX14_03_M02798 TRANSFAC - 3598293 3598308 5.0E-06 TTCAAATACAATTTTA 16 V_HOX13_02_M01452 TRANSFAC + 3597793 3597808 2.0E-06 AAAATAATTAGAAAAG 16 V_NANOG_02_M01247 TRANSFAC + 3598277 3598296 6.0E-06 TTTGGAAGTCAAAAGATAAA 20 V_GATA1_06_M00347 TRANSFAC + 3598288 3598297 1.0E-05 AAAGATAAAA 10 V_HOXC8_01_M01321 TRANSFAC - 3597793 3597808 7.0E-06 CTTTTCTAATTATTTT 16 V_IPF1_06_M01438 TRANSFAC + 3597793 3597808 3.0E-06 AAAATAATTAGAAAAG 16

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.