Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

WRN Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 7486 Werner syndrome, RecQ helicase-like chr8 + 30885777 - 30891277 30890777 Transcription Factor Binding Sites   Download all TFBS in the WRN promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints HSF2_HSF_DBD_trimeric_13_1 SELEX - 30891609 30891621 9.0E-06 TTCCAGAATCTCC 13 Foxa2_MA0047.2 JASPAR + 30891732 30891743 5.0E-06 TGTTTACCTTGC 12 EVX2_homeodomain_DBD_monomeric_10_1 SELEX + 30892459 30892468 1.0E-05 GATAATTATC 10 EVX2_homeodomain_DBD_monomeric_10_1 SELEX - 30892459 30892468 1.0E-05 GATAATTATC 10 Pax5_MA0014.1 JASPAR - 30890943 30890962 4.0E-06 AGTGCACTGAGGAAGAGCGG 20 Hoxd9_homeodomain_DBD_monomeric_10_1 SELEX - 30892404 30892413 7.0E-06 GCCATAAAAT 10 DLX1_homeodomain_DBD_monomeric_10_1 SELEX + 30892459 30892468 3.0E-06 GATAATTATC 10 DLX1_homeodomain_DBD_monomeric_10_1 SELEX - 30892459 30892468 3.0E-06 GATAATTATC 10 FOXA1_MA0148.1 JASPAR + 30891732 30891742 4.0E-06 TGTTTACCTTG 11 EVX1_homeodomain_DBD_monomeric_10_1 SELEX + 30892459 30892468 4.0E-06 GATAATTATC 10 EVX1_homeodomain_DBD_monomeric_10_1 SELEX - 30892459 30892468 4.0E-06 GATAATTATC 10 FOXF2_MA0030.1 JASPAR - 30891730 30891743 3.0E-06 GCAAGGTAAACATC 14 HINFP1_C2H2_full_dimeric_20_1 SELEX - 30890792 30890811 2.0E-06 GCGGCCCCCGCAGCGGCCGC 20 FOXC1_forkhead_DBD_monomeric_11_1 SELEX - 30891731 30891741 6.0E-06 AAGGTAAACAT 11 Spz1_MA0111.1 JASPAR + 30891209 30891219 7.0E-06 AGGGTTGCAGC 11 Tcfcp2l1_MA0145.1 JASPAR + 30892468 30892481 4.0E-06 CCAGCTCAGACCGG 14 HOXD11_homeodomain_DBD_monomeric_10_2 SELEX - 30892405 30892414 6.0E-06 AGCCATAAAA 10 POU6F2_POU_DBD_dimeric_16_1 SELEX + 30892452 30892467 1.0E-06 TTTAAGAGATAATTAT 16 POU6F2_POU_DBD_dimeric_16_1 SELEX - 30892452 30892467 2.0E-06 ATAATTATCTCTTAAA 16 BHLHE23_bHLH_DBD_dimeric_10_1 SELEX - 30892394 30892403 9.0E-06 GCCATATGCT 10 GRHL1_CP2_DBD_dimer-of-dimers_17_1 SELEX + 30891464 30891480 9.0E-06 GACCTGTTGGACTGGAT 17 FOXJ3_forkhead_DBD_dimeric_14_1 SELEX - 30892316 30892329 4.0E-06 GTAAACCAATAACA 14 HOXC11_homeodomain_full_monomeric_11_2 SELEX - 30892404 30892414 2.0E-06 AGCCATAAAAT 11 SP1_MA0079.2 JASPAR - 30890338 30890347 3.0E-06 CCCCTCCCCC 10 SP1_MA0079.2 JASPAR - 30891244 30891253 7.0E-06 CCCCGCCCCC 10 SP1_MA0079.2 JASPAR - 30891273 30891282 7.0E-06 CCCCGCCCCC 10 MGA_TBX_DBD_dimeric_18_2 SELEX + 30891045 30891062 6.0E-06 GGCGGGAATGTTCTCACT 18 HESX1_homeodomain_DBD_dimeric_15_1 SELEX + 30892453 30892467 9.0E-06 TTAAGAGATAATTAT 15 HESX1_homeodomain_DBD_dimeric_15_1 SELEX - 30892453 30892467 5.0E-06 ATAATTATCTCTTAA 15 LHX9_homeodomain_DBD_dimeric_13_1 SELEX + 30892454 30892466 2.0E-06 TAAGAGATAATTA 13 Hoxd9_homeodomain_DBD_monomeric_9_1 SELEX - 30892405 30892413 4.0E-06 GCCATAAAA 9 Pou5f1_MA0142.1 JASPAR + 30892498 30892512 4.0E-06 TTTTTTCATTCTAAT 15 PLAG1_MA0163.1 JASPAR - 30891711 30891724 9.0E-06 GGGGCCGTCAGGGG 14 NRF1_NRF_full_dimeric_12_1 SELEX + 30891158 30891169 1.0E-06 CACGCATGCGCA 12 NRF1_NRF_full_dimeric_12_1 SELEX - 30891158 30891169 2.0E-06 TGCGCATGCGTG 12 Hoxa11_homeodomain_DBD_monomeric_11_1 SELEX - 30892404 30892414 3.0E-06 AGCCATAAAAT 11 CDX2_homeodomain_DBD_monomeric_9_1 SELEX - 30892405 30892413 8.0E-06 GCCATAAAA 9 CDX1_homeodomain_DBD_monomeric_9_1 SELEX - 30892405 30892413 8.0E-06 GCCATAAAA 9 HOXA10_homeodomain_DBD_monomeric_11_1 SELEX - 30892404 30892414 6.0E-06 AGCCATAAAAT 11 DLX5_homeodomain_FL_monomeric_8_1 SELEX + 30892460 30892467 4.0E-06 ATAATTAT 8 DLX5_homeodomain_FL_monomeric_8_1 SELEX - 30892460 30892467 4.0E-06 ATAATTAT 8 V_HOXA9_01_M01351 TRANSFAC - 30892400 30892416 8.0E-06 GAAGCCATAAAATGCCA 17 V_HSF2_01_M00147 TRANSFAC + 30891049 30891058 1.0E-05 GGAATGTTCT 10 V_AP2ALPHA_Q6_M01857 TRANSFAC - 30891240 30891250 6.0E-06 CGCCCCCGGCC 11 V_HNF3B_01_M00131 TRANSFAC + 30892491 30892505 1.0E-05 GGGACTGTTTTTTCA 15 V_KLF15_Q2_M01714 TRANSFAC + 30890339 30890352 5.0E-06 GGGGAGGGGTGTTG 14 V_GEN_INI_B_M00315 TRANSFAC - 30892191 30892198 1.0E-05 CCTCATTT 8 V_BCL6_Q3_01_M02085 TRANSFAC + 30891763 30891772 9.0E-06 CTTTCTAGTA 10 V_ZFP410_04_M02936 TRANSFAC + 30891703 30891719 8.0E-06 TTTCCCCGCCCCTGACG 17 V_MAFK_03_M02776 TRANSFAC + 30891378 30891392 1.0E-06 AAAGTTTGCTGATTT 15 V_DLX3_01_M01400 TRANSFAC + 30892455 30892471 3.0E-06 AAGAGATAATTATCCAG 17 V_DLX3_01_M01400 TRANSFAC - 30892456 30892472 1.0E-05 GCTGGATAATTATCTCT 17 V_MAFB_05_M02775 TRANSFAC + 30891379 30891395 4.0E-06 AAGTTTGCTGATTTGGT 17 V_POU5F1_02_M02245 TRANSFAC + 30892498 30892512 4.0E-06 TTTTTTCATTCTAAT 15 V_GABPA_04_M02858 TRANSFAC - 30891014 30891029 5.0E-06 CCATCTTCCCACCTGT 16 V_SP1_03_M02281 TRANSFAC - 30890338 30890347 3.0E-06 CCCCTCCCCC 10 V_SP1_03_M02281 TRANSFAC - 30891244 30891253 7.0E-06 CCCCGCCCCC 10 V_SP1_03_M02281 TRANSFAC - 30891273 30891282 7.0E-06 CCCCGCCCCC 10 V_GKLF_02_M01588 TRANSFAC - 30891179 30891190 5.0E-06 GCCCCGCCCAGC 12 V_SP1_02_M01303 TRANSFAC + 30891274 30891284 8.0E-06 GGGGCGGGGAC 11 V_LYF1_01_M00141 TRANSFAC + 30891605 30891613 3.0E-06 TTTGGGAGA 9 V_LDSPOLYA_B_M00317 TRANSFAC + 30892492 30892507 1.0E-06 GGACTGTTTTTTCATT 16 V_DLX5_01_M01388 TRANSFAC - 30892455 30892470 1.0E-06 TGGATAATTATCTCTT 16 V_NKX62_Q2_M00489 TRANSFAC + 30892457 30892468 4.0E-06 GAGATAATTATC 12 V_BARBIE_01_M00238 TRANSFAC + 30892267 30892281 1.0E-05 TTTTAAAGGCGAAGG 15 V_ZNF219_01_M01122 TRANSFAC - 30890333 30890344 1.0E-05 CTCCCCCACCCC 12 V_GEN_INI3_B_M00314 TRANSFAC - 30892191 30892198 1.0E-05 CCTCATTT 8 V_HOXB13_01_M01467 TRANSFAC - 30892312 30892327 4.0E-06 AAACCAATAACAATTC 16 V_FOXO1_02_M00474 TRANSFAC + 30891728 30891741 5.0E-06 TTGATGTTTACCTT 14 V_HNF3G_Q4_M02015 TRANSFAC - 30890313 30890320 7.0E-06 TGTTTGTT 8 V_HNF1_Q6_M00790 TRANSFAC + 30892315 30892332 2.0E-06 TTGTTATTGGTTTACAGA 18 V_XFD3_01_M00269 TRANSFAC - 30891728 30891741 3.0E-06 AAGGTAAACATCAA 14 V_DOBOX4_01_M01359 TRANSFAC - 30891529 30891545 5.0E-06 ACTATAGATACCCCGGG 17 V_KROX_Q6_M00982 TRANSFAC - 30890333 30890346 8.0E-06 CCCTCCCCCACCCC 14 V_KROX_Q6_M00982 TRANSFAC - 30891239 30891252 5.0E-06 CCCGCCCCCGGCCC 14 V_KROX_Q6_M00982 TRANSFAC - 30891268 30891281 2.0E-06 CCCGCCCCCGTTCC 14 V_ZBP89_Q4_M01816 TRANSFAC - 30890337 30890346 4.0E-06 CCCTCCCCCA 10 V_HOXB9_01_M01426 TRANSFAC - 30892401 30892416 0.0E+00 GAAGCCATAAAATGCC 16 V_CDX2_01_M01449 TRANSFAC - 30892402 30892417 1.0E-06 AGAAGCCATAAAATGC 16 V_MAZ_Q6_01_M02023 TRANSFAC + 30890848 30890861 1.0E-06 AGGGGAGGGAAGGG 14 V_AP2BETA_Q3_M01858 TRANSFAC + 30891572 30891587 4.0E-06 GCTTAGGCCCGCGGAG 16 V_HNF3_Q6_M00791 TRANSFAC - 30892494 30892506 5.0E-06 ATGAAAAAACAGT 13 V_MEF2_03_M00232 TRANSFAC - 30890032 30890053 1.0E-05 CCGCTTCCTAAAGATAGCCGAA 22 V_TATA_C_M00216 TRANSFAC - 30892266 30892275 6.0E-06 CCTTTAAAAA 10 V_CDX1_01_M01373 TRANSFAC - 30892402 30892417 4.0E-06 AGAAGCCATAAAATGC 16 V_POU6F1_01_M00465 TRANSFAC - 30891376 30891386 8.0E-06 GCAAACTTTAT 11 V_SP1_01_M00008 TRANSFAC - 30890898 30890907 7.0E-06 GAGGCGGGGT 10 V_OCT4_02_M01124 TRANSFAC + 30892499 30892513 3.0E-06 TTTTTCATTCTAATG 15 V_HOXD9_Q2_M01834 TRANSFAC - 30892405 30892414 6.0E-06 AGCCATAAAA 10 V_SP4_Q5_M01273 TRANSFAC - 30891244 30891254 9.0E-06 TCCCCGCCCCC 11 V_SP4_Q5_M01273 TRANSFAC - 30891273 30891283 9.0E-06 TCCCCGCCCCC 11 V_FREAC2_01_M00290 TRANSFAC - 30891728 30891743 2.0E-06 GCAAGGTAAACATCAA 16 V_S8_01_M00099 TRANSFAC + 30892455 30892470 3.0E-06 AAGAGATAATTATCCA 16 V_CAAT_01_M00254 TRANSFAC - 30892348 30892359 3.0E-06 TACAGCCAATCA 12 V_LBP9_01_M01592 TRANSFAC - 30892465 30892481 8.0E-06 CCGGTCTGAGCTGGATA 17 V_LUN1_01_M00480 TRANSFAC + 30892219 30892235 8.0E-06 TCCCAGTTGCCTTGGGG 17 V_GATA3_02_M00350 TRANSFAC + 30892456 30892465 7.0E-06 AGAGATAATT 10 V_NANOG_01_M01123 TRANSFAC + 30892210 30892221 3.0E-06 GGACTCATTTCC 12 V_GEN_INI2_B_M00313 TRANSFAC - 30892191 30892198 1.0E-05 CCTCATTT 8 V_ZFP206_01_M01742 TRANSFAC - 30891159 30891169 2.0E-06 TGCGCATGCGT 11 V_TBX15_02_M01264 TRANSFAC + 30891016 30891033 5.0E-06 AGGTGGGAAGATGGGAAT 18 V_FOXA2_03_M02260 TRANSFAC + 30891732 30891743 5.0E-06 TGTTTACCTTGC 12 V_NRF1_Q6_M00652 TRANSFAC + 30891160 30891169 2.0E-06 CGCATGCGCA 10 V_IRF6_04_M02874 TRANSFAC - 30892474 30892488 5.0E-06 CTCACTCCCGGTCTG 15 V_ZFP281_01_M01597 TRANSFAC + 30890337 30890347 1.0E-06 TGGGGGAGGGG 11 V_ZFP281_04_M02831 TRANSFAC - 30890335 30890349 4.0E-06 CACCCCTCCCCCACC 15 V_RFX3_05_M02892 TRANSFAC + 30892243 30892265 0.0E+00 CTTCAGCCTTGGTTACAAGCAGG 23 V_FREAC4_01_M00292 TRANSFAC - 30891728 30891743 2.0E-06 GCAAGGTAAACATCAA 16 V_SP1_Q2_01_M00933 TRANSFAC - 30891244 30891253 4.0E-06 CCCCGCCCCC 10 V_SP1_Q2_01_M00933 TRANSFAC - 30891273 30891282 4.0E-06 CCCCGCCCCC 10 V_SP1_Q2_01_M00933 TRANSFAC + 30891706 30891715 7.0E-06 CCCCGCCCCT 10 V_UF1H3BETA_Q6_M01068 TRANSFAC + 30890335 30890348 1.0E-06 GGTGGGGGAGGGGT 14 V_CMAF_01_M01070 TRANSFAC + 30891379 30891397 4.0E-06 AAGTTTGCTGATTTGGTGT 19 V_NFYA_Q5_M02106 TRANSFAC - 30892344 30892357 7.0E-06 CAGCCAATCACTAA 14 V_P300_01_M00033 TRANSFAC + 30892477 30892490 3.0E-06 ACCGGGAGTGAGAC 14 V_DLX1_01_M01439 TRANSFAC + 30892455 30892468 4.0E-06 AAGAGATAATTATC 14 V_FOXK1_03_M02752 TRANSFAC - 30891727 30891743 9.0E-06 GCAAGGTAAACATCAAG 17 V_OCT4_01_M01125 TRANSFAC + 30892498 30892512 2.0E-06 TTTTTTCATTCTAAT 15

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.