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TYK2 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 7297 tyrosine kinase 2 chr19 - 10490748 - 10496248 10491248 Transcription Factor Binding Sites   Download all TFBS in the TYK2 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints Uncx_homeodomain_DBD_monomeric_8_1 SELEX - 10490822 10490829 9.0E-06 CTAATTAA 8 VSX1_homeodomain_full_monomeric_11_1 SELEX - 10490821 10490831 7.0E-06 GGCTAATTAAG 11 LMX1A_homeodomain_DBD_monomeric_8_1 SELEX - 10490822 10490829 9.0E-06 CTAATTAA 8 ISX_homeodomain_full_monomeric_8_1 SELEX - 10490822 10490829 5.0E-06 CTAATTAA 8 Shox2_homeodomain_DBD_monomeric_8_1 SELEX - 10490822 10490829 5.0E-06 CTAATTAA 8 EWSR1-FLI1_MA0149.1 JASPAR - 10490898 10490915 3.0E-06 AGAAAGGAGGAAGGAGGA 18 NFYA_MA0060.1 JASPAR - 10491367 10491382 7.0E-06 CAGGACCAATGAGAGT 16 NFYA_MA0060.1 JASPAR - 10491401 10491416 9.0E-06 CTCAGCCAATCGCGGC 16 NKX6-2_homeodomain_full_monomeric_8_1 SELEX - 10490822 10490829 5.0E-06 CTAATTAA 8 GCM1_GCM_full_dimeric_16_1 SELEX + 10490664 10490679 6.0E-06 CTGAGGGCGCCAGTAT 16 GCM1_GCM_full_dimeric_16_1 SELEX - 10490664 10490679 1.0E-06 ATACTGGCGCCCTCAG 16 PRRX2_homeodomain_full_monomeric_8_1 SELEX - 10490822 10490829 5.0E-06 CTAATTAA 8 IRF7_IRF_DBD_trimeric_17_1 SELEX - 10491333 10491349 8.0E-06 AAAAAAAAAATCCAATG 17 LMX1B_homeodomain_full_monomeric_8_1 SELEX - 10490822 10490829 9.0E-06 CTAATTAA 8 SPIB_ETS_DBD_monomeric_14_1 SELEX - 10490894 10490907 4.0E-06 GGAAGGAGGAAGTA 14 Spz1_MA0111.1 JASPAR + 10491840 10491850 3.0E-06 AGGGTAGCAGC 11 SHOX_homeodomain_DBD_monomeric_8_1 SELEX - 10490822 10490829 9.0E-06 CTAATTAA 8 EMX1_homeodomain_DBD_monomeric_10_1 SELEX + 10490821 10490830 8.0E-06 CTTAATTAGC 10 PRRX1_homeodomain_full_monomeric_8_1 SELEX - 10490822 10490829 5.0E-06 CTAATTAA 8 SP1_MA0079.2 JASPAR - 10491474 10491483 3.0E-06 CCCCTCCCCC 10 Ascl2_bHLH_DBD_dimeric_10_1 SELEX - 10491303 10491312 6.0E-06 AGCAGCTGCC 10 DLX6_homeodomain_DBD_monomeric_8_1 SELEX - 10490822 10490829 5.0E-06 CTAATTAA 8 NOTO_homeodomain_DBD_monomeric_10_1 SELEX - 10490821 10490830 7.0E-06 GCTAATTAAG 10 Vsx1_homeodomain_DBD_monomeric_8_1 SELEX - 10490822 10490829 5.0E-06 CTAATTAA 8 DLX3_homeodomain_DBD_monomeric_8_1 SELEX - 10490822 10490829 9.0E-06 CTAATTAA 8 LHX2_homeodomain_DBD_monomeric_10_1 SELEX - 10490821 10490830 3.0E-06 GCTAATTAAG 10 Foxd3_MA0041.1 JASPAR + 10491338 10491349 7.0E-06 GATTTTTTTTTT 12 EN1_homeodomain_full_dimeric_14_1 SELEX + 10490815 10490828 3.0E-06 TAAGCGCTTAATTA 14 LHX9_homeodomain_DBD_monomeric_8_1 SELEX - 10490822 10490829 5.0E-06 CTAATTAA 8 POU6F2_POU_full_monomeric_10_1 SELEX - 10490821 10490830 9.0E-06 GCTAATTAAG 10 GBX2_homeodomain_DBD_dimeric_14_1 SELEX - 10490815 10490828 1.0E-05 TAATTAAGCGCTTA 14 SPI1_ETS_full_monomeric_14_1 SELEX - 10490894 10490907 5.0E-06 GGAAGGAGGAAGTA 14 REST_MA0138.2 JASPAR - 10491364 10491384 5.0E-06 CCCAGGACCAATGAGAGTGCC 21 ZNF524_C2H2_full_monomeric_14_1 SELEX + 10491205 10491218 1.0E-06 CTCGAACCCGGACC 14 RAXL1_homeodomain_DBD_monomeric_8_1 SELEX - 10490822 10490829 5.0E-06 CTAATTAA 8 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 10491340 10491352 6.0E-06 AAAAAAAAAAAAA 13 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 10491342 10491354 5.0E-06 GCAAAAAAAAAAA 13 RORA_2_MA0072.1 JASPAR + 10491556 10491569 5.0E-06 TGGAATTGGGTCAG 14 Lhx4_homeodomain_DBD_monomeric_8_1 SELEX - 10490822 10490829 9.0E-06 CTAATTAA 8 V_SPI1_01_M01203 TRANSFAC - 10490891 10490907 4.0E-06 GGAAGGAGGAAGTAGGC 17 V_SPI1_01_M01203 TRANSFAC - 10490898 10490914 9.0E-06 GAAAGGAGGAAGGAGGA 17 V_MSX3_01_M01341 TRANSFAC - 10490819 10490834 1.0E-05 AAAGGCTAATTAAGCG 16 V_HMGIY_Q3_M01010 TRANSFAC + 10491334 10491348 0.0E+00 ATTGGATTTTTTTTT 15 V_FOXD3_01_M00130 TRANSFAC + 10491338 10491349 8.0E-06 GATTTTTTTTTT 12 V_MAFB_03_M02879 TRANSFAC - 10491345 10491359 4.0E-06 CCATGGCAAAAAAAA 15 V_DR4_Q2_M00965 TRANSFAC + 10491573 10491589 4.0E-06 TGTACGGTCCTGACCCT 17 V_MAF_Q6_M00648 TRANSFAC - 10490890 10490905 3.0E-06 AAGGAGGAAGTAGGCT 16 V_SP1_03_M02281 TRANSFAC - 10491474 10491483 3.0E-06 CCCCTCCCCC 10 V_P50RELAP65_Q5_01_M01224 TRANSFAC + 10491537 10491548 9.0E-06 GGAGTTCCCCTC 12 V_E2A_Q2_M00804 TRANSFAC + 10491777 10491790 1.0E-06 CCACCTGCCCCAGT 14 V_VAX2_01_M01327 TRANSFAC - 10490819 10490834 8.0E-06 AAAGGCTAATTAAGCG 16 V_HEN1_01_M00068 TRANSFAC + 10491074 10491095 6.0E-06 CGAGGCACCAGGTGCTCCCATC 22 V_COUPTF_Q6_M01036 TRANSFAC + 10491578 10491600 7.0E-06 GGTCCTGACCCTAGGACACAGCT 23 V_PU1_Q4_M01172 TRANSFAC + 10490888 10490906 4.0E-06 GGAGCCTACTTCCTCCTTC 19 V_PU1_Q4_M01172 TRANSFAC + 10490895 10490913 2.0E-06 ACTTCCTCCTTCCTCCTTT 19 V_NFY_Q6_01_M00775 TRANSFAC - 10491405 10491417 3.0E-06 ACTCAGCCAATCG 13 V_TCFAP2E_04_M02926 TRANSFAC - 10491338 10491351 9.0E-06 AAAAAAAAAAAATC 14 V_TCFAP2E_04_M02926 TRANSFAC - 10491339 10491352 3.0E-06 AAAAAAAAAAAAAT 14 V_TCFAP2E_04_M02926 TRANSFAC - 10491340 10491353 2.0E-06 CAAAAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC - 10491342 10491355 5.0E-06 GGCAAAAAAAAAAA 14 V_TCFAP2C_04_M02925 TRANSFAC + 10491294 10491307 7.0E-06 ACGCCCATTGGCAG 14 V_TCFAP2C_04_M02925 TRANSFAC - 10491659 10491672 4.0E-06 AAGCCAAAGGGCAG 14 V_PAX4_01_M00373 TRANSFAC + 10491561 10491581 5.0E-06 TTGGGTCAGGCGTGTACGGTC 21 V_ELF4_04_M02850 TRANSFAC - 10491337 10491353 7.0E-06 CAAAAAAAAAAAAATCC 17 V_ELF4_04_M02850 TRANSFAC - 10491338 10491354 0.0E+00 GCAAAAAAAAAAAAATC 17 V_ELF4_04_M02850 TRANSFAC - 10491339 10491355 1.0E-06 GGCAAAAAAAAAAAAAT 17 V_ELF4_04_M02850 TRANSFAC - 10491340 10491356 1.0E-06 TGGCAAAAAAAAAAAAA 17 V_GC_01_M00255 TRANSFAC + 10491473 10491486 8.0E-06 CGGGGGAGGGGCTT 14 V_ZFP105_03_M02827 TRANSFAC - 10491337 10491351 7.0E-06 AAAAAAAAAAAATCC 15 V_ZFP105_03_M02827 TRANSFAC - 10491338 10491352 5.0E-06 AAAAAAAAAAAAATC 15 V_ZFP105_03_M02827 TRANSFAC - 10491339 10491353 2.0E-06 CAAAAAAAAAAAAAT 15 V_ZFP105_03_M02827 TRANSFAC - 10491340 10491354 8.0E-06 GCAAAAAAAAAAAAA 15 V_ZFP105_03_M02827 TRANSFAC - 10491341 10491355 2.0E-06 GGCAAAAAAAAAAAA 15 V_ZBP89_Q4_M01816 TRANSFAC + 10490996 10491005 6.0E-06 TCCTCCCCCC 10 V_MATH1_Q2_M01716 TRANSFAC - 10491079 10491088 9.0E-06 GCACCTGGTG 10 V_ASCL2_03_M02737 TRANSFAC - 10491299 10491315 7.0E-06 CAGAGCAGCTGCCAATG 17 V_ASCL2_03_M02737 TRANSFAC + 10491300 10491316 1.0E-06 ATTGGCAGCTGCTCTGT 17 V_POU6F1_01_M00465 TRANSFAC + 10491935 10491945 5.0E-06 ACATACATTAT 11 V_CTCF_01_M01200 TRANSFAC + 10490656 10490675 7.0E-06 TGAGCCTCCTGAGGGCGCCA 20 V_BLIMP1_Q6_M01066 TRANSFAC - 10491694 10491709 8.0E-06 AAACGAGGGAAAGGAG 16 V_NKX23_01_M01457 TRANSFAC + 10490812 10490827 8.0E-06 CAGTAAGCGCTTAATT 16 V_SP4_Q5_M01273 TRANSFAC - 10491474 10491484 5.0E-06 GCCCCTCCCCC 11 V_ELF1_Q6_M00746 TRANSFAC - 10490895 10490906 7.0E-06 GAAGGAGGAAGT 12 V_ATF1_Q6_M00691 TRANSFAC + 10490940 10490950 8.0E-06 CTTTGAAGACA 11 V_MTF1_06_M02882 TRANSFAC - 10491338 10491351 2.0E-06 AAAAAAAAAAAATC 14 V_MTF1_06_M02882 TRANSFAC - 10491340 10491353 8.0E-06 CAAAAAAAAAAAAA 14 V_HEN1_02_M00058 TRANSFAC - 10491074 10491095 7.0E-06 GATGGGAGCACCTGGTGCCTCG 22 V_AIRE_01_M00999 TRANSFAC - 10490830 10490855 9.0E-06 ACATGAATAGGTATTAATGGCAAAGG 26 V_NFY_01_M00287 TRANSFAC - 10491367 10491382 6.0E-06 CAGGACCAATGAGAGT 16 V_BDP1_01_M01796 TRANSFAC - 10491871 10491882 8.0E-06 GGATTTGAATTC 12 V_REST_02_M02256 TRANSFAC - 10491364 10491384 5.0E-06 CCCAGGACCAATGAGAGTGCC 21 V_ZFP281_01_M01597 TRANSFAC + 10491473 10491483 7.0E-06 CGGGGGAGGGG 11 V_CHX10_01_M00437 TRANSFAC + 10490820 10490833 3.0E-06 GCTTAATTAGCCTT 14 V_SRF_06_M02916 TRANSFAC - 10491335 10491351 3.0E-06 AAAAAAAAAAAATCCAA 17 V_SRF_06_M02916 TRANSFAC - 10491336 10491352 4.0E-06 AAAAAAAAAAAAATCCA 17 V_SRF_06_M02916 TRANSFAC - 10491337 10491353 0.0E+00 CAAAAAAAAAAAAATCC 17 V_SRF_06_M02916 TRANSFAC - 10491338 10491354 0.0E+00 GCAAAAAAAAAAAAATC 17 V_SRF_06_M02916 TRANSFAC - 10491339 10491355 0.0E+00 GGCAAAAAAAAAAAAAT 17 V_SRF_06_M02916 TRANSFAC - 10491340 10491356 2.0E-06 TGGCAAAAAAAAAAAAA 17 V_SRF_06_M02916 TRANSFAC - 10491341 10491357 4.0E-06 ATGGCAAAAAAAAAAAA 17 V_POU6F1_03_M01479 TRANSFAC + 10490818 10490834 1.0E-05 GCGCTTAATTAGCCTTT 17 V_VAX1_01_M01397 TRANSFAC + 10490819 10490834 9.0E-06 CGCTTAATTAGCCTTT 16 V_EWSR1FLI1_01_M02252 TRANSFAC - 10490898 10490915 3.0E-06 AGAAAGGAGGAAGGAGGA 18 V_UF1H3BETA_Q6_M01068 TRANSFAC + 10491471 10491484 1.0E-06 GACGGGGGAGGGGC 14 V_MAFK_04_M02880 TRANSFAC - 10491333 10491347 4.0E-06 AAAAAAAATCCAATG 15 V_NFYA_Q5_M02106 TRANSFAC - 10491268 10491281 3.0E-06 CGGCCAATGGGAGG 14 V_NFYA_Q5_M02106 TRANSFAC - 10491401 10491414 8.0E-06 CAGCCAATCGCGGC 14 V_TCF3_05_M02920 TRANSFAC - 10491341 10491355 4.0E-06 GGCAAAAAAAAAAAA 15 V_TCF3_05_M02920 TRANSFAC - 10491342 10491356 0.0E+00 TGGCAAAAAAAAAAA 15 V_TCF3_05_M02920 TRANSFAC - 10491343 10491357 1.0E-06 ATGGCAAAAAAAAAA 15 V_RORA2_01_M00157 TRANSFAC + 10491557 10491569 5.0E-06 GGAATTGGGTCAG 13

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.