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TSC2 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 7249 tuberous sclerosis 2 chr16 + 2092989 - 2098489 2097989 Transcription Factor Binding Sites   Download all TFBS in the TSC2 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints CTCF_MA0139.1 JASPAR + 2097896 2097914 1.0E-06 TTTCCGCCAGAGGGCGGCA 19 GABPA_MA0062.2 JASPAR + 2097969 2097979 4.0E-06 CCGGAAGTGCG 11 FLI1_ETS_full_monomeric_10_1 SELEX + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 ETV5_ETS_DBD_monomeric_10_1 SELEX + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 ERG_ETS_full_monomeric_10_1 SELEX + 2097968 2097977 1.0E-06 ACCGGAAGTG 10 ETV3_ETS_DBD_monomeric_10_1 SELEX + 2097968 2097977 1.0E-06 ACCGGAAGTG 10 FOXF2_MA0030.1 JASPAR + 2094333 2094346 1.0E-05 TAGCAGTAAACAAA 14 Arx_homeodomain_DBD_dimeric_13_1 SELEX + 2095021 2095033 4.0E-06 TTAAATGAATTAT 13 Arx_homeodomain_DBD_dimeric_13_1 SELEX - 2095021 2095033 5.0E-06 ATAATTCATTTAA 13 FEV_ETS_DBD_monomeric_10_1 SELEX + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 ZNF75A_C2H2_DBD_monomeric_12_1 SELEX + 2097298 2097309 7.0E-06 TGTTTTCCCTCA 12 ZNF75A_C2H2_DBD_monomeric_12_1 SELEX - 2097452 2097463 1.0E-05 TCCTTTCCCACC 12 Bhlhb2_bHLH_DBD_dimeric_10_1 SELEX - 2097870 2097879 1.0E-06 ATCACGTGAC 10 EWSR1-FLI1_MA0149.1 JASPAR + 2094409 2094426 4.0E-06 GAAGCAGAGGAAGGAAGG 18 EWSR1-FLI1_MA0149.1 JASPAR + 2094413 2094430 5.0E-06 CAGAGGAAGGAAGGGAGG 18 EWSR1-FLI1_MA0149.1 JASPAR + 2094417 2094434 0.0E+00 GGAAGGAAGGGAGGATGC 18 ETV1_ETS_DBD_monomeric_10_1 SELEX + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 Alx1_homeodomain_DBD_dimeric_13_1 SELEX + 2095021 2095033 5.0E-06 TTAAATGAATTAT 13 Alx1_homeodomain_DBD_dimeric_13_1 SELEX - 2095021 2095033 4.0E-06 ATAATTCATTTAA 13 FOXO1_forkhead_DBD_monomeric_8_1 SELEX + 2094338 2094345 7.0E-06 GTAAACAA 8 ISX_homeodomain_DBD_dimeric_13_1 SELEX + 2095021 2095033 3.0E-06 TTAAATGAATTAT 13 Klf4_MA0039.2 JASPAR - 2094198 2094207 5.0E-06 TGGGTGGGGC 10 USF1_bHLH_DBD_dimeric_10_1 SELEX + 2097870 2097879 2.0E-06 GTCACGTGAT 10 USF1_bHLH_DBD_dimeric_10_1 SELEX - 2097870 2097879 1.0E-06 ATCACGTGAC 10 ETV2_ETS_DBD_monomeric_11_1 SELEX + 2097967 2097977 8.0E-06 TACCGGAAGTG 11 PROP1_homeodomain_full_dimeric_11_1 SELEX + 2095022 2095032 4.0E-06 TAAATGAATTA 11 ALX3_homeodomain_full_dimeric_13_1 SELEX + 2095021 2095033 6.0E-06 TTAAATGAATTAT 13 ALX3_homeodomain_full_dimeric_13_1 SELEX - 2095021 2095033 5.0E-06 ATAATTCATTTAA 13 BHLHE41_bHLH_full_dimeric_10_1 SELEX + 2097870 2097879 3.0E-06 GTCACGTGAT 10 BHLHE41_bHLH_full_dimeric_10_1 SELEX - 2097870 2097879 2.0E-06 ATCACGTGAC 10 ETS1_ETS_full_monomeric_10_1 SELEX + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 SREBF2_bHLH_DBD_dimeric_10_1 SELEX + 2097870 2097879 2.0E-06 GTCACGTGAT 10 SREBF2_bHLH_DBD_dimeric_10_1 SELEX - 2097870 2097879 1.0E-06 ATCACGTGAC 10 SP1_MA0079.2 JASPAR + 2093917 2093926 9.0E-06 CCCCTCCTCC 10 Bhlhb2_bHLH_DBD_monomeric_10_1 SELEX - 2097870 2097879 1.0E-06 ATCACGTGAC 10 ETV4_ETS_DBD_monomeric_10_1 SELEX + 2097968 2097977 4.0E-06 ACCGGAAGTG 10 ELK4_ETS_DBD_monomeric_10_1 SELEX + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 DRGX_homeodomain_DBD_dimeric_13_1 SELEX + 2095021 2095033 6.0E-06 TTAAATGAATTAT 13 DRGX_homeodomain_DBD_dimeric_13_1 SELEX - 2095021 2095033 7.0E-06 ATAATTCATTTAA 13 ELK4_MA0076.1 JASPAR + 2097968 2097976 4.0E-06 ACCGGAAGT 9 Alx4_homeodomain_DBD_dimeric_13_1 SELEX + 2095021 2095033 5.0E-06 TTAAATGAATTAT 13 Alx4_homeodomain_DBD_dimeric_13_1 SELEX - 2095021 2095033 4.0E-06 ATAATTCATTTAA 13 Srebf1_bHLH_DBD_dimeric_10_1 SELEX + 2097870 2097879 2.0E-06 GTCACGTGAT 10 Srebf1_bHLH_DBD_dimeric_10_1 SELEX - 2097870 2097879 1.0E-06 ATCACGTGAC 10 TFEB_bHLH_full_dimeric_10_1 SELEX + 2097870 2097879 5.0E-06 GTCACGTGAT 10 TFEB_bHLH_full_dimeric_10_1 SELEX - 2097870 2097879 1.0E-06 ATCACGTGAC 10 CTCF_C2H2_full_monomeric_17_1 SELEX - 2097897 2097913 9.0E-06 GCCGCCCTCTGGCGGAA 17 PRRX1_homeodomain_full_dimeric_11_1 SELEX + 2095022 2095032 8.0E-06 TAAATGAATTA 11 CART1_homeodomain_DBD_dimeric_13_1 SELEX + 2095021 2095033 1.0E-05 TTAAATGAATTAT 13 CART1_homeodomain_DBD_dimeric_13_1 SELEX - 2095021 2095033 8.0E-06 ATAATTCATTTAA 13 Uncx_homeodomain_DBD_dimeric_13_1 SELEX + 2095021 2095033 2.0E-06 TTAAATGAATTAT 13 ERF_ETS_DBD_monomeric_10_1 SELEX + 2097968 2097977 1.0E-06 ACCGGAAGTG 10 MLXIPL_bHLH_full_dimeric_10_1 SELEX + 2097870 2097879 1.0E-06 GTCACGTGAT 10 MLXIPL_bHLH_full_dimeric_10_1 SELEX - 2097870 2097879 5.0E-06 ATCACGTGAC 10 ELK1_ETS_full_monomeric_10_1 SELEX + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 ZNF282_C2H2_DBD_monomeric_17_1 SELEX - 2097445 2097461 6.0E-06 CTTTCCCACCACTCTGT 17 TFAP2C_TFAP_full_dimeric_12_1 SELEX + 2093583 2093594 6.0E-06 TGCCCCAGGCCA 12 TFE3_bHLH_DBD_dimeric_10_1 SELEX + 2097870 2097879 9.0E-06 GTCACGTGAT 10 TFE3_bHLH_DBD_dimeric_10_1 SELEX - 2097870 2097879 1.0E-06 ATCACGTGAC 10 TFEC_bHLH_DBD_dimeric_10_1 SELEX + 2097870 2097879 4.0E-06 GTCACGTGAT 10 TFEC_bHLH_DBD_dimeric_10_1 SELEX - 2097870 2097879 2.0E-06 ATCACGTGAC 10 GABPA_ETS_full_monomeric_10_1 SELEX + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 VDR_nuclearreceptor_full_dimeric_16_1 SELEX + 2097378 2097393 6.0E-06 GAGGACAGCAAGTTCA 16 Elk3_ETS_DBD_monomeric_10_1 SELEX + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 ETV6_ETS_full_monomeric_10_1 SELEX + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 FOXB1_forkhead_full_monomeric_9_1 SELEX + 2094337 2094345 7.0E-06 AGTAAACAA 9 REST_MA0138.2 JASPAR + 2093991 2094011 9.0E-06 GCCAGCACCCAGGCCAGGCCA 21 ETV6_ETS_full_dimeric_15_1 SELEX + 2097963 2097977 5.0E-06 CCGCTACCGGAAGTG 15 FOXO3_forkhead_full_monomeric_8_1 SELEX + 2094338 2094345 7.0E-06 GTAAACAA 8 MLX_bHLH_full_dimeric_10_1 SELEX + 2097870 2097879 1.0E-06 GTCACGTGAT 10 MLX_bHLH_full_dimeric_10_1 SELEX - 2097870 2097879 2.0E-06 ATCACGTGAC 10 PLAG1_MA0163.1 JASPAR + 2094180 2094193 7.0E-06 GGGTGCCAAGGGGA 14 PLAG1_MA0163.1 JASPAR + 2097479 2097492 1.0E-06 GGGGCGAAAGGGGG 14 ARNTL_bHLH_DBD_dimeric_10_1 SELEX + 2097870 2097879 2.0E-06 GTCACGTGAT 10 ARNTL_bHLH_DBD_dimeric_10_1 SELEX - 2097870 2097879 3.0E-06 ATCACGTGAC 10 BHLHB3_bHLH_full_dimeric_10_1 SELEX - 2097870 2097879 3.0E-06 ATCACGTGAC 10 V_ERG_03_M02062 TRANSFAC + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 V_ERM_01_M01992 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_NFKB_C_M00208 TRANSFAC - 2097432 2097443 3.0E-06 CGGGACTCTCCA 12 V_SAP1A_01_M01167 TRANSFAC + 2097967 2097977 4.0E-06 TACCGGAAGTG 11 V_ELK1_04_M01165 TRANSFAC + 2097967 2097977 1.0E-06 TACCGGAAGTG 11 V_USF_Q6_M00187 TRANSFAC + 2097870 2097879 7.0E-06 GTCACGTGAT 10 V_GABPA_02_M02074 TRANSFAC + 2097968 2097977 8.0E-06 ACCGGAAGTG 10 V_SRY_07_M02813 TRANSFAC + 2097268 2097283 2.0E-06 GATAAATATAATAAGT 16 V_SRY_07_M02813 TRANSFAC - 2097268 2097283 4.0E-06 ACTTATTATATTTATC 16 V_FOXA2_04_M02749 TRANSFAC + 2094333 2094349 3.0E-06 TAGCAGTAAACAAAGGG 17 V_NRSF_Q4_M01028 TRANSFAC + 2097609 2097627 2.0E-06 CCCCTGCCCGCGCAGCTGG 19 V_EVI1_04_M00081 TRANSFAC + 2097267 2097281 9.0E-06 GGATAAATATAATAA 15 V_CETS1_01_M01986 TRANSFAC + 2097968 2097977 4.0E-06 ACCGGAAGTG 10 V_AR_Q6_01_M01996 TRANSFAC - 2097378 2097392 8.0E-06 GAACTTGCTGTCCTC 15 V_ETV3_01_M01990 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_PROP1_01_M01294 TRANSFAC - 2095022 2095032 2.0E-06 TAATTCATTTA 11 V_GABP_B_M00341 TRANSFAC + 2097968 2097979 0.0E+00 ACCGGAAGTGCG 12 V_GABP_B_M00341 TRANSFAC - 2097983 2097994 5.0E-06 GCCGGAAGCGCG 12 V_MEF2_02_M00231 TRANSFAC - 2094139 2094160 7.0E-06 AGATGGGTTTTAAATAGCCCTC 22 V_GABPA_04_M02858 TRANSFAC - 2097535 2097550 8.0E-06 CCTTTTTCCCAAAGAT 16 V_FOXJ1_03_M02750 TRANSFAC + 2094335 2094350 6.0E-06 GCAGTAAACAAAGGGA 16 V_SP1_03_M02281 TRANSFAC + 2093917 2093926 9.0E-06 CCCCTCCTCC 10 V_GKLF_02_M01588 TRANSFAC + 2094198 2094209 3.0E-06 GCCCCACCCACC 12 V_NERF_Q2_M00531 TRANSFAC + 2094057 2094074 3.0E-06 CTTCAGGAAGGAGGGCTG 18 V_HEN1_01_M00068 TRANSFAC - 2097566 2097587 9.0E-06 ACGGTTCCCACGTGCGGCCCTG 22 V_LYF1_01_M00141 TRANSFAC + 2097538 2097546 9.0E-06 TTTGGGAAA 9 V_AP4_Q6_01_M00927 TRANSFAC + 2094091 2094099 6.0E-06 ACCAGCTGC 9 V_SOX21_03_M02803 TRANSFAC + 2097268 2097283 2.0E-06 GATAAATATAATAAGT 16 V_SOX21_03_M02803 TRANSFAC - 2097268 2097283 3.0E-06 ACTTATTATATTTATC 16 V_CETS2_02_M02064 TRANSFAC + 2097968 2097977 6.0E-06 ACCGGAAGTG 10 V_MEF2A_Q6_M02024 TRANSFAC + 2094145 2094154 5.0E-06 TATTTAAAAC 10 V_PEA3_01_M01991 TRANSFAC + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 V_FLI1_01_M02038 TRANSFAC + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 V_ELK1_06_M02059 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_MTERF_01_M01245 TRANSFAC + 2094953 2094966 7.0E-06 TGGGTATGTTTGGT 14 V_POU3F2_01_M00463 TRANSFAC + 2097269 2097282 9.0E-06 ATAAATATAATAAG 14 V_FREAC3_01_M00291 TRANSFAC + 2094333 2094348 3.0E-06 TAGCAGTAAACAAAGG 16 V_ELK1_05_M01981 TRANSFAC + 2097968 2097977 5.0E-06 ACCGGAAGTG 10 V_SAP1A_02_M01983 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_FLI1_02_M02073 TRANSFAC + 2097968 2097977 5.0E-06 ACCGGAAGTG 10 V_SREBP1_01_M00220 TRANSFAC + 2097869 2097879 4.0E-06 CGTCACGTGAT 11 V_SREBP1_01_M00220 TRANSFAC - 2097870 2097880 1.0E-06 CATCACGTGAC 11 V_PET1_02_M02072 TRANSFAC + 2097968 2097977 6.0E-06 ACCGGAAGTG 10 V_ERF_01_M01984 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_AP1_Q6_01_M00925 TRANSFAC - 2098207 2098215 9.0E-06 ATGACTTAA 9 V_ER81_02_M02065 TRANSFAC + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 V_IRF3_Q3_M01279 TRANSFAC - 2094344 2094356 6.0E-06 CGCCTTTCCCTTT 13 V_MAZ_Q6_01_M02023 TRANSFAC - 2093916 2093929 1.0E-06 GTGGGAGGAGGGGG 14 V_ERG_01_M01752 TRANSFAC + 2097968 2097976 4.0E-06 ACCGGAAGT 9 V_GABPA_01_M02039 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_CETS2_01_M01989 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_MEF2_03_M00232 TRANSFAC - 2094139 2094160 4.0E-06 AGATGGGTTTTAAATAGCCCTC 22 V_MATH1_Q2_M01716 TRANSFAC - 2094090 2094099 3.0E-06 GCAGCTGGTG 10 V_GADP_01_M01258 TRANSFAC - 2097966 2097977 6.0E-06 CACTTCCGGTAG 12 V_PET1_01_M02037 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_IK2_01_M00087 TRANSFAC + 2097537 2097548 2.0E-06 CTTTGGGAAAAA 12 V_HBP1_03_M02762 TRANSFAC + 2095018 2095033 6.0E-06 AGCTTAAATGAATTAT 16 V_SP1SP3_Q4_M01219 TRANSFAC + 2093916 2093926 1.0E-05 CCCCCTCCTCC 11 V_SP1SP3_Q4_M01219 TRANSFAC + 2097672 2097682 5.0E-06 CCGCCTCCTCC 11 V_MEF2_Q6_01_M00941 TRANSFAC + 2094142 2094153 3.0E-06 GGCTATTTAAAA 12 V_CETS1P54_01_M00032 TRANSFAC + 2097968 2097977 5.0E-06 ACCGGAAGTG 10 V_TBP_06_M02814 TRANSFAC - 2097268 2097283 3.0E-06 ACTTATTATATTTATC 16 V_PEA3_02_M02066 TRANSFAC + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 V_ERF_02_M02061 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_SOX11_03_M02795 TRANSFAC + 2094336 2094352 5.0E-06 CAGTAAACAAAGGGAAA 17 V_CTCF_01_M01200 TRANSFAC + 2097895 2097914 2.0E-06 CTTTCCGCCAGAGGGCGGCA 20 V_ER71_01_M01988 TRANSFAC + 2097968 2097977 5.0E-06 ACCGGAAGTG 10 V_NET_01_M01982 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_CETS1P54_03_M01078 TRANSFAC + 2097965 2097980 9.0E-06 GCTACCGGAAGTGCGG 16 V_ER81_01_M01987 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_ERM_02_M02069 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_GABPBETA_Q3_M01876 TRANSFAC + 2097968 2097978 1.0E-06 ACCGGAAGTGC 11 V_AP4_01_M00005 TRANSFAC - 2094068 2094085 5.0E-06 AGCCCCAGCTCCAGCCCT 18 V_STRA13_01_M00985 TRANSFAC + 2097868 2097881 3.0E-06 CCGTCACGTGATGC 14 V_STRA13_01_M00985 TRANSFAC - 2097868 2097881 7.0E-06 GCATCACGTGACGG 14 V_TFEB_01_M01768 TRANSFAC + 2097870 2097879 2.0E-06 GTCACGTGAT 10 V_TFEB_01_M01768 TRANSFAC - 2097870 2097879 2.0E-06 ATCACGTGAC 10 V_FOXL1_04_M02753 TRANSFAC + 2094333 2094349 7.0E-06 TAGCAGTAAACAAAGGG 17 V_AIRE_01_M00999 TRANSFAC + 2094946 2094971 3.0E-06 TCTGGTTTGGGTATGTTTGGTCATCT 26 V_TCF7_04_M02921 TRANSFAC - 2097269 2097283 7.0E-06 ACTTATTATATTTAT 15 V_ZFP161_04_M02933 TRANSFAC + 2097952 2097965 6.0E-06 TCCGCGCAATGCCG 14 V_NRF2_01_M00108 TRANSFAC + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 V_FPM315_01_M01587 TRANSFAC - 2093918 2093929 4.0E-06 GTGGGAGGAGGG 12 V_REST_02_M02256 TRANSFAC + 2093991 2094011 9.0E-06 GCCAGCACCCAGGCCAGGCCA 21 V_BBX_03_M02739 TRANSFAC - 2095018 2095032 1.0E-06 TAATTCATTTAAGCT 15 V_SAP1A_03_M02058 TRANSFAC + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 V_CETS1_02_M02063 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_EWSR1FLI1_01_M02252 TRANSFAC + 2094409 2094426 4.0E-06 GAAGCAGAGGAAGGAAGG 18 V_EWSR1FLI1_01_M02252 TRANSFAC + 2094413 2094430 5.0E-06 CAGAGGAAGGAAGGGAGG 18 V_EWSR1FLI1_01_M02252 TRANSFAC + 2094417 2094434 0.0E+00 GGAAGGAAGGGAGGATGC 18 V_SOX4_01_M01308 TRANSFAC + 2094341 2094348 1.0E-05 AACAAAGG 8 V_SOX1_03_M02802 TRANSFAC - 2095020 2095035 1.0E-06 AGATAATTCATTTAAG 16 V_NET_02_M02060 TRANSFAC + 2097968 2097977 4.0E-06 ACCGGAAGTG 10 V_FOXO1_01_M00473 TRANSFAC + 2094337 2094346 3.0E-06 AGTAAACAAA 10 V_HNF3B_Q6_M02014 TRANSFAC - 2094337 2094345 2.0E-06 TTGTTTACT 9 V_ERG_02_M01985 TRANSFAC + 2097968 2097977 2.0E-06 ACCGGAAGTG 10 V_MEF2A_05_M01301 TRANSFAC + 2094142 2094153 2.0E-06 GGCTATTTAAAA 12 V_ER71_02_M02067 TRANSFAC + 2097968 2097977 3.0E-06 ACCGGAAGTG 10 V_FOXK1_03_M02752 TRANSFAC + 2094333 2094349 9.0E-06 TAGCAGTAAACAAAGGG 17 V_PAX4_04_M00380 TRANSFAC - 2094934 2094963 2.0E-06 AAACATACCCAAACCAGACCTCCCCACCCC 30 V_PAX4_04_M00380 TRANSFAC + 2097268 2097297 5.0E-06 GATAAATATAATAAGTGCCATGCCCTTTCC 30 V_SOX9_Q4_M01284 TRANSFAC + 2094340 2094350 0.0E+00 AAACAAAGGGA 11 V_SOX14_03_M02798 TRANSFAC + 2097268 2097283 0.0E+00 GATAAATATAATAAGT 16 V_SOX14_03_M02798 TRANSFAC - 2097268 2097283 1.0E-06 ACTTATTATATTTATC 16 V_ETV3_02_M02068 TRANSFAC + 2097968 2097977 2.0E-06 ACCGGAAGTG 10

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