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TOP1 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 7150 topoisomerase (DNA) I chr20 + 39652461 - 39657961 39657461 Transcription Factor Binding Sites   Download all TFBS in the TOP1 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints HSF2_HSF_DBD_trimeric_13_1 SELEX + 39652516 39652528 1.0E-06 TTCTAGAACCTTA 13 FOXJ2_forkhead_DBD_dimeric_13_1 SELEX - 39652602 39652614 8.0E-06 ATACACAAATACA 13 NF-kappaB_MA0061.1 JASPAR + 39659292 39659301 2.0E-06 GGGAATTCCC 10 NF-kappaB_MA0061.1 JASPAR - 39659292 39659301 2.0E-06 GGGAATTCCC 10 RARB_nuclearreceptor_full_dimeric_16_1 SELEX - 39652512 39652527 9.0E-06 AAGGTTCTAGAATTCA 16 HSF1_HSF_full_trimeric_13_1 SELEX + 39652516 39652528 5.0E-06 TTCTAGAACCTTA 13 FOXL1_forkhead_full_dimeric_13_1 SELEX - 39659023 39659035 6.0E-06 CTTCAATAAATAA 13 POU5F1P1_POU_DBD_monomeric_9_1 SELEX + 39657294 39657302 2.0E-06 TATGCAAAT 9 HINFP1_C2H2_full_dimeric_20_1 SELEX + 39657307 39657326 3.0E-06 GCGGAGCGCGCACGGTCCGG 20 POU2F3_POU_DBD_monomeric_9_1 SELEX + 39657294 39657302 2.0E-06 TATGCAAAT 9 POU1F1_POU_DBD_monomeric_14_1 SELEX - 39652454 39652467 6.0E-06 AGTATGTAGATTAG 7 POU1F1_POU_DBD_monomeric_14_1 SELEX + 39657292 39657305 2.0E-06 CTTATGCAAATCAC 14 ERG_ETS_full_dimeric_14_1 SELEX - 39658076 39658089 2.0E-06 ATCGGAAATCCGCT 14 SOX9_HMG_DBD_monomeric_9_1 SELEX - 39658226 39658234 9.0E-06 GAACAATGG 9 POU2F2_POU_DBD_monomeric_11_1 SELEX + 39657293 39657303 1.0E-06 TTATGCAAATC 11 POU3F4_POU_DBD_monomeric_9_1 SELEX + 39657294 39657302 2.0E-06 TATGCAAAT 9 HOMEZ_HOMEZ_DBD_monomer-or-dimer_12_1 SELEX + 39659014 39659025 4.0E-06 AAAAAGATTTTA 12 Pou2f2_POU_DBD_monomeric_9_1 SELEX + 39657294 39657302 2.0E-06 TATGCAAAT 9 TCF7L1_HMG_full_monomeric_12_1 SELEX + 39656371 39656382 4.0E-06 AGACTTCAAAGG 12 LEF1_HMG_DBD_monomeric_15_1 SELEX + 39656371 39656385 6.0E-06 AGACTTCAAAGGCTT 15 POU3F3_POU_DBD_monomeric_13_1 SELEX - 39652455 39652467 9.0E-06 AGTATGTAGATTA 7 POU3F3_POU_DBD_monomeric_13_1 SELEX + 39657292 39657304 4.0E-06 CTTATGCAAATCA 13 NR4A2_nuclearreceptor_full_dimeric_16_1 SELEX + 39657125 39657140 3.0E-06 CGGCCTTTAAAGGCCC 16 NR4A2_nuclearreceptor_full_dimeric_16_1 SELEX - 39657125 39657140 1.0E-06 GGGCCTTTAAAGGCCG 16 Gfi_MA0038.1 JASPAR + 39657298 39657307 2.0E-06 CAAATCACAG 10 NFATC1_NFAT_full_dimeric_20_1 SELEX + 39652491 39652510 4.0E-06 GATGGAACCACTCTTTTCTT 20 NFATC1_NFAT_full_dimeric_20_1 SELEX + 39659007 39659026 8.0E-06 GGAGGAAAAAAAGATTTTAT 20 Tcf7_HMG_DBD_monomeric_12_1 SELEX + 39656371 39656382 6.0E-06 AGACTTCAAAGG 12 Mycn_MA0104.2 JASPAR + 39657141 39657150 3.0E-06 ACCACGTGGC 10 POU3F1_POU_DBD_monomeric_12_1 SELEX + 39657293 39657304 1.0E-06 TTATGCAAATCA 12 Hltf_MA0109.1 JASPAR + 39659436 39659445 1.0E-05 AACCTTATGT 10 POU2F1_POU_DBD_monomeric_12_1 SELEX + 39657292 39657303 1.0E-06 CTTATGCAAATC 12 HLF_MA0043.1 JASPAR + 39657479 39657490 9.0E-06 TGTTACACAACT 12 IRF5_IRF_full_dimeric_14_1 SELEX - 39659336 39659349 8.0E-06 CCGGAACCCAAACT 14 SOX9_MA0077.1 JASPAR - 39658226 39658234 5.0E-06 GAACAATGG 9 POU3F2_POU_DBD_monomeric_12_1 SELEX + 39657293 39657304 0.0E+00 TTATGCAAATCA 12 FLI1_ETS_full_monomeric_14_1 SELEX - 39658076 39658089 3.0E-06 ATCGGAAATCCGCT 14 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 39652602 39652614 9.0E-06 ATACACAAATACA 13 NFE2L2_MA0150.1 JASPAR - 39661095 39661105 4.0E-06 ATGACTCAGCC 11 V_RUSH1A_02_M01107 TRANSFAC + 39659436 39659445 1.0E-05 AACCTTATGT 10 V_HOXA9_01_M01351 TRANSFAC - 39659020 39659036 8.0E-06 GCTTCAATAAATAAAAT 17 V_FOXP1_01_M00987 TRANSFAC + 39652595 39652614 3.0E-06 ACATCTGTGTATTTGTGTAT 20 V_FOXP1_01_M00987 TRANSFAC + 39660988 39661007 2.0E-06 TTATTTATATTTAAAATGTT 20 V_NFKAPPAB65_01_M00052 TRANSFAC + 39659292 39659301 1.0E-05 GGGAATTCCC 10 V_NFKAPPAB65_01_M00052 TRANSFAC - 39659292 39659301 1.0E-05 GGGAATTCCC 10 V_NFKB_C_M00208 TRANSFAC + 39659291 39659302 4.0E-06 TGGGAATTCCCA 12 V_NFKB_C_M00208 TRANSFAC - 39659291 39659302 4.0E-06 TGGGAATTCCCA 12 V_STAT5A_Q6_M01890 TRANSFAC - 39657222 39657234 2.0E-06 CTTTTTCTCGGAA 13 V_DBX1_01_M01483 TRANSFAC - 39660988 39661004 3.0E-06 ATTTTAAATATAAATAA 17 V_FREAC7_01_M00293 TRANSFAC - 39659020 39659035 6.0E-06 CTTCAATAAATAAAAT 16 V_NFKB_Q6_01_M00774 TRANSFAC + 39659287 39659302 2.0E-06 GTGCTGGGAATTCCCA 16 V_NFKB_Q6_01_M00774 TRANSFAC - 39659291 39659306 1.0E-06 TCAGTGGGAATTCCCA 16 V_CDX2_Q5_01_M01659 TRANSFAC - 39659023 39659033 1.0E-06 TCAATAAATAA 11 V_BTEB3_Q5_M01865 TRANSFAC + 39657273 39657285 9.0E-06 CCGTGGGAGGAGT 13 V_MAFK_03_M02776 TRANSFAC + 39660998 39661012 6.0E-06 TTAAAATGTTGACAG 15 V_MMEF2_Q6_M00405 TRANSFAC - 39660990 39661005 3.0E-06 CATTTTAAATATAAAT 16 V_GATA3_03_M00351 TRANSFAC + 39659016 39659025 3.0E-06 AAAGATTTTA 10 V_HOXA13_02_M01297 TRANSFAC - 39659020 39659028 4.0E-06 AAATAAAAT 9 V_OCT1_Q5_01_M00930 TRANSFAC - 39657294 39657304 0.0E+00 TGATTTGCATA 11 V_MEF2_02_M00231 TRANSFAC - 39659018 39659039 3.0E-06 TTTGCTTCAATAAATAAAATCT 22 V_ZTA_Q2_M00711 TRANSFAC - 39661098 39661110 2.0E-06 TAATAATGACTCA 13 V_IRF_Q6_01_M00972 TRANSFAC - 39658057 39658067 7.0E-06 GAAAAAGAAAA 11 V_IRF_Q6_01_M00972 TRANSFAC - 39658416 39658426 7.0E-06 GAAAAAGAAAA 11 V_IRF2_Q6_M01882 TRANSFAC - 39658054 39658069 4.0E-06 TGGAAAAAGAAAAGGA 16 V_IRF2_Q6_M01882 TRANSFAC - 39658413 39658428 7.0E-06 GAGAAAAAGAAAATGG 16 V_NFAT3_Q3_M01734 TRANSFAC - 39659009 39659018 6.0E-06 TTTTTTTCCT 10 V_OCT1_01_M00135 TRANSFAC + 39657289 39657307 1.0E-06 CTCCTTATGCAAATCACAG 19 V_NKX25_Q6_M02108 TRANSFAC - 39659452 39659462 8.0E-06 CCCACTTCAAA 11 V_POU2F3_01_M01476 TRANSFAC + 39657291 39657306 1.0E-06 CCTTATGCAAATCACA 16 V_GATA1_03_M00127 TRANSFAC - 39652451 39652464 4.0E-06 ATGTAGATTAGGGA 4 V_FOXO3A_Q1_M01137 TRANSFAC - 39659020 39659031 2.0E-06 AATAAATAAAAT 12 V_STAT5B_01_M00459 TRANSFAC - 39657219 39657233 8.0E-06 TTTTTCTCGGAACCC 15 V_FOXJ1_03_M02750 TRANSFAC - 39659018 39659033 5.0E-06 TCAATAAATAAAATCT 16 V_OCT_C_M00210 TRANSFAC - 39657293 39657305 1.0E-06 GTGATTTGCATAA 13 V_PU1_Q4_M01172 TRANSFAC - 39659004 39659022 3.0E-06 AATCTTTTTTTCCTCCTTA 19 V_HOXD13_01_M01404 TRANSFAC - 39659017 39659032 6.0E-06 CAATAAATAAAATCTT 16 V_HBP1_Q2_M01661 TRANSFAC - 39659026 39659034 4.0E-06 TTCAATAAA 9 V_MEF2A_Q6_M02024 TRANSFAC + 39660995 39661004 9.0E-06 TATTTAAAAT 10 V_AP1_Q6_M00174 TRANSFAC - 39661096 39661106 6.0E-06 AATGACTCAGC 11 V_ELF4_04_M02850 TRANSFAC - 39659019 39659035 2.0E-06 CTTCAATAAATAAAATC 17 V_ELF4_04_M02850 TRANSFAC - 39659020 39659036 3.0E-06 GCTTCAATAAATAAAAT 17 V_ELF4_04_M02850 TRANSFAC - 39660987 39661003 6.0E-06 TTTTAAATATAAATAAC 17 V_ELF4_04_M02850 TRANSFAC - 39660988 39661004 8.0E-06 ATTTTAAATATAAATAA 17 V_BACH1_01_M00495 TRANSFAC + 39661094 39661108 7.0E-06 GGGCTGAGTCATTAT 15 V_GC_01_M00255 TRANSFAC + 39657324 39657337 7.0E-06 CGGAGGCGGGGCTT 14 V_TCF3_04_M02816 TRANSFAC + 39656370 39656386 9.0E-06 CAGACTTCAAAGGCTTA 17 V_POU3F2_01_M00463 TRANSFAC - 39659017 39659030 6.0E-06 ATAAATAAAATCTT 14 V_IPF1_Q4_M00436 TRANSFAC - 39661100 39661111 9.0E-06 GTAATAATGACT 12 V_ZFP105_03_M02827 TRANSFAC - 39659017 39659031 7.0E-06 AATAAATAAAATCTT 15 V_ZFP105_03_M02827 TRANSFAC - 39659020 39659034 5.0E-06 TTCAATAAATAAAAT 15 V_POLY_C_M00212 TRANSFAC - 39659011 39659028 5.0E-06 AAATAAAATCTTTTTTTC 18 V_XFD3_01_M00269 TRANSFAC - 39661000 39661013 4.0E-06 ACTGTCAACATTTT 14 V_RSRFC4_Q2_M00407 TRANSFAC - 39660988 39661004 1.0E-06 ATTTTAAATATAAATAA 17 V_AMEF2_Q6_M00403 TRANSFAC - 39660988 39661005 7.0E-06 CATTTTAAATATAAATAA 18 V_AP1_Q6_01_M00925 TRANSFAC - 39661097 39661105 7.0E-06 ATGACTCAG 9 V_NFKB_Q6_M00194 TRANSFAC - 39659290 39659303 8.0E-06 GTGGGAATTCCCAG 14 MYC_MAX_MA0059.1 JASPAR - 39657141 39657151 5.0E-06 AGCCACGTGGT 11 V_AP2BETA_Q3_M01858 TRANSFAC - 39658126 39658141 9.0E-06 GCCGGCGGCTGGGGGG 16 V_OCT1_05_M00161 TRANSFAC - 39657292 39657305 2.0E-06 GTGATTTGCATAAG 14 V_IRF_Q6_M00772 TRANSFAC + 39658053 39658067 5.0E-06 CTCCTTTTCTTTTTC 15 V_IRF_Q6_M00772 TRANSFAC + 39658412 39658426 1.0E-06 GCCATTTTCTTTTTC 15 V_HNF1_Q6_01_M01011 TRANSFAC - 39660986 39661006 9.0E-06 ACATTTTAAATATAAATAACA 21 V_MEF2_03_M00232 TRANSFAC - 39660987 39661008 8.0E-06 CAACATTTTAAATATAAATAAC 22 V_ISRE_01_M00258 TRANSFAC + 39658414 39658428 7.0E-06 CATTTTCTTTTTCTC 15 V_ELF5_01_M01197 TRANSFAC + 39652526 39652536 1.0E-06 TTAAGGAAGTT 11 V_OCT1_04_M00138 TRANSFAC + 39660982 39661004 2.0E-06 ACTCTGTTATTTATATTTAAAAT 23 V_PITX3_01_M01343 TRANSFAC - 39659314 39659329 4.0E-06 AGCAGGATTATGTACC 16 V_NFKAPPAB50_01_M00051 TRANSFAC + 39659292 39659301 6.0E-06 GGGAATTCCC 10 V_NFKAPPAB50_01_M00051 TRANSFAC - 39659292 39659301 6.0E-06 GGGAATTCCC 10 V_BBX_04_M02843 TRANSFAC + 39661000 39661016 9.0E-06 AAAATGTTGACAGTGAG 17 V_AP1_C_M00199 TRANSFAC - 39661097 39661105 6.0E-06 ATGACTCAG 9 V_OCAB_Q6_M02113 TRANSFAC + 39657293 39657303 1.0E-06 TTATGCAAATC 11 V_XFD2_01_M00268 TRANSFAC - 39659020 39659033 7.0E-06 TCAATAAATAAAAT 14 V_ARID3A_04_M02735 TRANSFAC - 39660989 39661005 6.0E-06 CATTTTAAATATAAATA 17 V_MYCN_01_M02259 TRANSFAC + 39657141 39657150 3.0E-06 ACCACGTGGC 10 V_AP1_01_M00517 TRANSFAC - 39661095 39661107 7.0E-06 TAATGACTCAGCC 13 V_TBP_06_M02814 TRANSFAC + 39660989 39661004 8.0E-06 TATTTATATTTAAAAT 16 V_TBP_06_M02814 TRANSFAC - 39660989 39661004 0.0E+00 ATTTTAAATATAAATA 16 V_TBP_06_M02814 TRANSFAC + 39660991 39661006 2.0E-06 TTTATATTTAAAATGT 16 V_TBP_06_M02814 TRANSFAC - 39660991 39661006 2.0E-06 ACATTTTAAATATAAA 16 V_IK3_01_M00088 TRANSFAC + 39659288 39659300 2.0E-06 TGCTGGGAATTCC 13 V_SOX9_B1_M00410 TRANSFAC - 39658224 39658237 6.0E-06 TGGGAACAATGGGG 14 V_OCT1_B_M00342 TRANSFAC + 39657294 39657303 1.0E-06 TATGCAAATC 10 V_OCT_Q6_M00795 TRANSFAC - 39657294 39657304 0.0E+00 TGATTTGCATA 11 V_EVI1_06_M00011 TRANSFAC - 39652611 39652619 9.0E-06 ACAAGATAC 9 V_MAF_Q6_01_M00983 TRANSFAC + 39661095 39661105 2.0E-06 GGCTGAGTCAT 11 V_ZFP691_04_M02937 TRANSFAC + 39656970 39656986 7.0E-06 GAGGGGACTCCTCCCAC 17 V_ZFP105_04_M02931 TRANSFAC - 39659022 39659038 4.0E-06 TTGCTTCAATAAATAAA 17 V_AP1_Q4_01_M00926 TRANSFAC + 39661098 39661105 1.0E-05 TGAGTCAT 8 V_MTF1_06_M02882 TRANSFAC - 39660993 39661006 8.0E-06 ACATTTTAAATATA 14 V_HOXB8_01_M01451 TRANSFAC - 39659022 39659037 4.0E-06 TGCTTCAATAAATAAA 16 V_OCT2_01_M01368 TRANSFAC + 39657291 39657306 1.0E-06 CCTTATGCAAATCACA 16 V_FOXL1_02_M02857 TRANSFAC - 39658035 39658050 7.0E-06 AATATCAAACAACAGC 16 V_OCT1_Q6_M00195 TRANSFAC + 39657291 39657305 3.0E-06 CCTTATGCAAATCAC 15 V_GFI1B_01_M01058 TRANSFAC + 39657298 39657309 5.0E-06 CAAATCACAGCG 12 V_ZBTB4_04_M02929 TRANSFAC - 39661003 39661018 6.0E-06 AACTCACTGTCAACAT 16 V_ZFP206_01_M01742 TRANSFAC + 39657443 39657453 4.0E-06 CGCGCAGGCGC 11 V_ZFP206_01_M01742 TRANSFAC - 39657444 39657454 8.0E-06 TGCGCCTGCGC 11 V_FRA1_Q5_M01267 TRANSFAC + 39661098 39661105 1.0E-05 TGAGTCAT 8 V_FPM315_01_M01587 TRANSFAC - 39657964 39657975 7.0E-06 CGGGGAGGACGG 12 V_NRF2_Q4_M00821 TRANSFAC + 39661094 39661106 1.0E-05 GGGCTGAGTCATT 13 V_ZBTB12_03_M02824 TRANSFAC - 39652513 39652529 0.0E+00 TTAAGGTTCTAGAATTC 17 V_TCF4_Q5_M00671 TRANSFAC - 39656375 39656382 1.0E-05 CCTTTGAA 8 V_STAT_01_M00223 TRANSFAC - 39659344 39659352 7.0E-06 TTCCCGGAA 9 V_FOX_Q2_M00809 TRANSFAC + 39659021 39659033 2.0E-06 TTTTATTTATTGA 13 V_PBX1_03_M01017 TRANSFAC - 39658038 39658049 6.0E-06 ATATCAAACAAC 12 V_RSRFC4_01_M00026 TRANSFAC + 39660989 39661004 2.0E-06 TATTTATATTTAAAAT 16 V_RSRFC4_01_M00026 TRANSFAC - 39660989 39661004 7.0E-06 ATTTTAAATATAAATA 16 V_BBX_03_M02739 TRANSFAC + 39659023 39659037 8.0E-06 TTATTTATTGAAGCA 15 V_EGR1_06_M02744 TRANSFAC - 39657368 39657381 5.0E-06 CCCGCCCCCTCGCT 14 V_LEF1TCF1_Q4_M00978 TRANSFAC - 39656372 39656382 4.0E-06 CCTTTGAAGTC 11 V_IRF1_Q6_01_M01881 TRANSFAC + 39658414 39658427 2.0E-06 CATTTTCTTTTTCT 14 V_NFKAPPAB_01_M00054 TRANSFAC + 39659292 39659301 2.0E-06 GGGAATTCCC 10 V_NFKAPPAB_01_M00054 TRANSFAC - 39659292 39659301 2.0E-06 GGGAATTCCC 10 V_HFH3_01_M00289 TRANSFAC + 39652601 39652613 4.0E-06 GTGTATTTGTGTA 13 V_HFH3_01_M00289 TRANSFAC + 39659021 39659033 3.0E-06 TTTTATTTATTGA 13 V_HSF2_02_M01244 TRANSFAC - 39652516 39652528 3.0E-06 TAAGGTTCTAGAA 13 V_VMAF_01_M00035 TRANSFAC - 39661092 39661110 1.0E-06 TAATAATGACTCAGCCCCA 19 V_NFE2_Q6_M02104 TRANSFAC - 39661091 39661106 6.0E-06 AATGACTCAGCCCCAC 16 V_HNF3B_Q6_M02014 TRANSFAC + 39659023 39659031 1.0E-05 TTATTTATT 9 V_NFE2L2_01_M02263 TRANSFAC - 39661095 39661105 4.0E-06 ATGACTCAGCC 11 V_UF1H3BETA_Q6_M01068 TRANSFAC + 39656963 39656976 6.0E-06 GGCTGGGGAGGGGA 14 V_SOX5_07_M02909 TRANSFAC + 39658946 39658962 2.0E-06 GGAAAGATTGTTGAGCA 17 V_ZFP128_04_M02932 TRANSFAC + 39660991 39661004 1.0E-06 TTTATATTTAAAAT 14 V_ZFP128_04_M02932 TRANSFAC - 39660991 39661004 9.0E-06 ATTTTAAATATAAA 14 V_EHF_07_M02849 TRANSFAC + 39661057 39661072 2.0E-06 AAAGACTTCCTAAGTA 16 V_GFI1_Q6_01_M02010 TRANSFAC - 39657298 39657307 2.0E-06 CTGTGATTTG 10 V_SMAD1_01_M01590 TRANSFAC - 39652502 39652513 5.0E-06 CAGAAGAAAAGA 12 V_SMAD1_01_M01590 TRANSFAC - 39658055 39658066 5.0E-06 AAAAAGAAAAGG 12 V_OCT4_01_M01125 TRANSFAC + 39660989 39661003 3.0E-06 TATTTATATTTAAAA 15 V_OTX3_01_M01403 TRANSFAC - 39659315 39659331 9.0E-06 TGAGCAGGATTATGTAC 17

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