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TK2 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 7084 thymidine kinase 2, mitochondrial chr16 - 66583228 - 66589315 66583728 Transcription Factor Binding Sites   Download all TFBS in the TK2 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints TBX20_TBX_full_monomeric_11_1 SELEX + 66586754 66586764 5.0E-06 TGGGTGTGAAG 11 Foxa2_MA0047.2 JASPAR + 66583175 66583186 9.0E-06 TATTTATTTAGA 12 NEUROD2_bHLH_full_dimeric_10_1 SELEX + 66583363 66583372 8.0E-06 GCCATATGGC 10 NEUROD2_bHLH_full_dimeric_10_1 SELEX - 66583363 66583372 8.0E-06 GCCATATGGC 10 IRF7_IRF_DBD_dimeric_14_1 SELEX + 66586634 66586647 4.0E-06 CCGAAAATAAAACA 14 FOXA1_MA0148.1 JASPAR + 66586781 66586791 2.0E-06 TGTTTGCTTTT 11 FOXC2_forkhead_DBD_monomeric_12_1 SELEX - 66583173 66583184 3.0E-06 TAAATAAATAAC 12 POU3F2_POU_DBD_monomeric_13_1 SELEX - 66583174 66583186 7.0E-06 TCTAAATAAATAA 13 FOXL1_forkhead_full_dimeric_13_1 SELEX - 66583174 66583186 1.0E-06 TCTAAATAAATAA 13 FOXL1_forkhead_full_dimeric_13_1 SELEX + 66585570 66585582 4.0E-06 CGTAAATAAACTT 13 POU3F4_POU_DBD_monomeric_11_1 SELEX - 66583174 66583184 7.0E-06 TAAATAAATAA 11 HINFP1_C2H2_full_dimeric_20_1 SELEX + 66586446 66586465 8.0E-06 GCGAACGCGGCGCCGTGCGC 20 FOXC1_forkhead_DBD_monomeric_11_1 SELEX - 66583174 66583184 1.0E-06 TAAATAAATAA 11 POU1F1_POU_DBD_monomeric_14_1 SELEX - 66583155 66583168 9.0E-06 AAAATGCAAAGTAT 14 REL_MA0101.1 JASPAR - 66583724 66583733 6.0E-06 CGGGATTTCC 10 Foxc1_forkhead_DBD_dimeric_11_1 SELEX - 66583175 66583185 5.0E-06 CTAAATAAATA 11 Foxc1_forkhead_DBD_dimeric_11_1 SELEX + 66585571 66585581 6.0E-06 GTAAATAAACT 11 RELA_MA0107.1 JASPAR - 66583724 66583733 8.0E-06 CGGGATTTCC 10 OTX2_homeodomain_DBD_monomeric_8_1 SELEX - 66585584 66585591 7.0E-06 TTAATCCT 8 NR4A2_nuclearreceptor_full_dimeric_16_1 SELEX + 66583606 66583621 5.0E-06 TGCTCTTTAAAGGCCC 16 NR4A2_nuclearreceptor_full_dimeric_16_1 SELEX - 66583606 66583621 3.0E-06 GGGCCTTTAAAGAGCA 16 SP1_MA0079.2 JASPAR + 66583460 66583469 3.0E-06 CCCCTCCCCC 10 FOXI1_MA0042.1 JASPAR - 66585250 66585261 9.0E-06 GAATATTTGGTT 12 YY2_C2H2_full_monomeric_11_1 SELEX + 66586176 66586186 8.0E-06 GCCGCCATTTC 11 FOXC2_forkhead_DBD_dimeric_11_1 SELEX - 66583175 66583185 2.0E-06 CTAAATAAATA 11 FOXC2_forkhead_DBD_dimeric_11_1 SELEX + 66585571 66585581 2.0E-06 GTAAATAAACT 11 SMAD3_MAD_DBD_dimeric_10_1 SELEX + 66585210 66585219 4.0E-06 CGTCTAGACT 10 PITX1_homeodomain_full_monomeric_9_1 SELEX - 66585584 66585592 9.0E-06 CTTAATCCT 9 T_TBX_full_dimeric_16_1 SELEX + 66583474 66583489 5.0E-06 TGGCACCAGAGTGTGA 16 T_TBX_full_dimeric_16_1 SELEX - 66583474 66583489 7.0E-06 TCACACTCTGGTGCCA 16 POU3F1_POU_DBD_monomeric_12_2 SELEX - 66583174 66583185 9.0E-06 CTAAATAAATAA 12 FEV_MA0156.1 JASPAR + 66583550 66583557 1.0E-05 CAGGAAAT 8 ZNF282_C2H2_DBD_monomeric_17_1 SELEX - 66586577 66586593 1.0E-06 CTTTCCCTCAACTCTTC 17 MAFK_bZIP_full_monomeric_12_1 SELEX - 66585314 66585325 2.0E-06 ATTTTTGCTGAG 12 NRF1_NRF_full_dimeric_12_1 SELEX - 66586431 66586442 2.0E-06 CGCGCATGCGCC 12 NRF1_NRF_full_dimeric_12_1 SELEX + 66586461 66586472 1.0E-06 TGCGCATGCGCG 12 NRF1_NRF_full_dimeric_12_1 SELEX - 66586461 66586472 0.0E+00 CGCGCATGCGCA 12 FOXC1_forkhead_DBD_dimeric_13_1 SELEX - 66583175 66583187 1.0E-06 ATCTAAATAAATA 13 BATF3_bZIP_DBD_dimeric_14_1 SELEX - 66586263 66586276 8.0E-06 TAATGACGGCAGCA 14 FOXB1_forkhead_DBD_monomeric_11_1 SELEX - 66583174 66583184 3.0E-06 TAAATAAATAA 11 POU4F1_POU_DBD_monomeric_14_1 SELEX - 66583172 66583185 7.0E-06 CTAAATAAATAACG 14 V_NFKAPPAB65_01_M00052 TRANSFAC - 66583724 66583733 9.0E-06 CGGGATTTCC 10 V_FREAC7_01_M00293 TRANSFAC - 66583171 66583186 2.0E-06 TCTAAATAAATAACGT 16 V_LEF1_04_M02774 TRANSFAC + 66586795 66586811 8.0E-06 CCTCGCTTTGATCAAGA 17 V_DEC2_Q2_M01843 TRANSFAC - 66586675 66586684 9.0E-06 CTTCACGTGG 10 V_CDX2_Q5_01_M01659 TRANSFAC + 66585568 66585578 4.0E-06 TCCGTAAATAA 11 V_FLI1_Q6_M01208 TRANSFAC + 66585489 66585499 7.0E-06 AAGGAAGTCAT 11 V_TBX15_01_M01263 TRANSFAC + 66586755 66586773 8.0E-06 GGGTGTGAAGTGCAAAGCT 19 V_TBX15_01_M01263 TRANSFAC - 66586755 66586773 1.0E-05 AGCTTTGCACTTCACACCC 19 V_FXR_Q3_M00631 TRANSFAC + 66585370 66585383 9.0E-06 CAAGTCCAGTAACC 14 V_AR_02_M00953 TRANSFAC - 66586281 66586307 6.0E-06 CCTGTTAGCCCGCCGTGTTCTGGCCTG 27 V_ATF5_01_M01295 TRANSFAC - 66584118 66584128 7.0E-06 CCTCTCCCTTC 11 V_FOXA2_04_M02749 TRANSFAC - 66583170 66583186 1.0E-05 TCTAAATAAATAACGTG 17 V_ZFX_01_M01593 TRANSFAC - 66583866 66583881 1.0E-05 CCCCGGGCCGCGGAGG 16 V_ZFX_01_M01593 TRANSFAC + 66586701 66586716 7.0E-06 GGCCGGGCCGCGGAGG 16 V_ETS_B_M00340 TRANSFAC + 66583548 66583561 2.0E-06 GACAGGAAATGGGT 14 V_ETS_B_M00340 TRANSFAC + 66585287 66585300 8.0E-06 GGGAGGAAGCATGT 14 V_TCF4_Q5_01_M02033 TRANSFAC - 66586797 66586806 9.0E-06 ATCAAAGCGA 10 V_HOXA13_02_M01297 TRANSFAC + 66586638 66586646 1.0E-06 AAATAAAAC 9 V_OCT1_Q5_01_M00930 TRANSFAC + 66583156 66583166 5.0E-06 TACTTTGCATT 11 V_RP58_01_M00532 TRANSFAC - 66585330 66585341 9.0E-06 TCCACATCTGGG 12 V_FOXO3A_Q1_M01137 TRANSFAC - 66583175 66583186 3.0E-06 TCTAAATAAATA 12 V_AP2_Q6_01_M00915 TRANSFAC - 66583880 66583892 9.0E-06 CCGGCCTCAGGCC 13 V_HNF3_Q6_01_M01012 TRANSFAC + 66583170 66583187 8.0E-06 CACGTTATTTATTTAGAT 18 V_SP1_03_M02281 TRANSFAC + 66583460 66583469 3.0E-06 CCCCTCCCCC 10 V_OCT_C_M00210 TRANSFAC + 66583155 66583167 6.0E-06 ATACTTTGCATTT 13 V_HTF_01_M00538 TRANSFAC + 66583161 66583184 3.0E-06 TGCATTTTCCACGTTATTTATTTA 24 V_HEN1_01_M00068 TRANSFAC + 66583280 66583301 2.0E-06 CTGGGACCCAGGTGTTCCTCTA 22 V_NFAT2_01_M01748 TRANSFAC - 66583164 66583172 8.0E-06 GTGGAAAAT 9 V_HMGA2_01_M01300 TRANSFAC + 66583164 66583178 7.0E-06 ATTTTCCACGTTATT 15 V_PAX5_02_M00144 TRANSFAC + 66583579 66583606 3.0E-06 GCCGGAATGTTCAGAGCGTGTCCGTCCT 28 V_ETS_Q4_M00771 TRANSFAC - 66583550 66583561 3.0E-06 ACCCATTTCCTG 12 V_TCF3_04_M02816 TRANSFAC - 66586795 66586811 5.0E-06 TCTTGATCAAAGCGAGG 17 V_LMX1_01_M01409 TRANSFAC - 66583173 66583189 8.0E-06 AGATCTAAATAAATAAC 17 V_ZFP410_03_M02832 TRANSFAC - 66583623 66583639 3.0E-06 GGTTCTGGGATGGAGAG 17 V_SOX8_04_M02912 TRANSFAC + 66586895 66586908 0.0E+00 TCATTCATGAAAAC 14 V_CREL_01_M00053 TRANSFAC - 66583724 66583733 6.0E-06 CGGGATTTCC 10 V_KROX_Q6_M00982 TRANSFAC + 66583695 66583708 3.0E-06 GCCGCCCCCGTCCC 14 V_ZBP89_Q4_M01816 TRANSFAC + 66583461 66583470 4.0E-06 CCCTCCCCCA 10 V_HNF3_Q6_M00791 TRANSFAC - 66583173 66583185 7.0E-06 CTAAATAAATAAC 13 V_HNF3_Q6_M00791 TRANSFAC - 66586779 66586791 4.0E-06 AAAAGCAAACAGG 13 V_OCT1_05_M00161 TRANSFAC + 66583155 66583168 0.0E+00 ATACTTTGCATTTT 14 V_HNF3ALPHA_Q6_M00724 TRANSFAC + 66583175 66583185 3.0E-06 TATTTATTTAG 11 V_HNF3ALPHA_Q6_M00724 TRANSFAC + 66586781 66586791 1.0E-06 TGTTTGCTTTT 11 V_NFE4_Q5_M02105 TRANSFAC + 66586196 66586207 5.0E-06 CTCCCTCTCCTC 12 V_OCT1_04_M00138 TRANSFAC + 66585289 66585311 5.0E-06 GAGGAAGCATGTAAATTCCATCA 23 V_REX1_03_M01744 TRANSFAC - 66586175 66586186 3.0E-06 GAAATGGCGGCC 12 V_HBP1_03_M02762 TRANSFAC - 66586890 66586905 5.0E-06 TTCATGAATGAGTGTG 16 V_PAX8_01_M00717 TRANSFAC - 66586893 66586907 6.0E-06 TTTTCATGAATGAGT 15 V_XFD2_01_M00268 TRANSFAC - 66583171 66583184 6.0E-06 TAAATAAATAACGT 14 V_RFX_Q6_M00975 TRANSFAC + 66585388 66585396 4.0E-06 CTGTTGCCA 9 V_HFH1_01_M00129 TRANSFAC - 66585573 66585584 4.0E-06 TGAAGTTTATTT 12 V_SMAD4_Q6_M00733 TRANSFAC + 66586560 66586574 1.0E-06 CTCAGGCAGCCAGCT 15 V_TBP_06_M02814 TRANSFAC - 66583171 66583186 5.0E-06 TCTAAATAAATAACGT 16 V_PAX8_B_M00328 TRANSFAC + 66586891 66586908 2.0E-06 ACACTCATTCATGAAAAC 18 V_SOX17_04_M02904 TRANSFAC + 66586891 66586907 1.0E-06 ACACTCATTCATGAAAA 17 V_TFIII_Q6_M00706 TRANSFAC - 66586195 66586203 6.0E-06 AGAGGGAGG 9 V_NEUROD_02_M01288 TRANSFAC + 66586596 66586607 6.0E-06 CTGCTGCTGGGT 12 V_HFH8_01_M00294 TRANSFAC + 66583172 66583184 2.0E-06 CGTTATTTATTTA 13 V_TAL1_01_M01591 TRANSFAC - 66585483 66585495 4.0E-06 CTTCCTTCTCCCT 13 V_FOXL1_02_M02857 TRANSFAC - 66583174 66583189 3.0E-06 AGATCTAAATAAATAA 16 V_FOXL1_02_M02857 TRANSFAC + 66586637 66586652 9.0E-06 AAAATAAAACATCGCC 16 V_OCT1_Q6_M00195 TRANSFAC - 66583155 66583169 0.0E+00 GAAAATGCAAAGTAT 15 V_OCT1_Q6_M00195 TRANSFAC + 66585293 66585307 4.0E-06 AAGCATGTAAATTCC 15 V_HEN1_02_M00058 TRANSFAC + 66583280 66583301 7.0E-06 CTGGGACCCAGGTGTTCCTCTA 22 V_XBP1_01_M00251 TRANSFAC - 66586670 66586686 9.0E-06 ATCTTCACGTGGCCTTT 17 V_ZFP206_01_M01742 TRANSFAC - 66586432 66586442 2.0E-06 CGCGCATGCGC 11 V_ZFP206_01_M01742 TRANSFAC + 66586461 66586471 0.0E+00 TGCGCATGCGC 11 V_ZFP206_01_M01742 TRANSFAC - 66586462 66586472 2.0E-06 CGCGCATGCGC 11 V_LMX1B_01_M01363 TRANSFAC + 66583173 66583189 9.0E-06 GTTATTTATTTAGATCT 17 V_ZBTB12_03_M02824 TRANSFAC + 66585221 66585237 7.0E-06 TAAACGTACTAGATCCC 17 V_FOXA2_03_M02260 TRANSFAC + 66583175 66583186 9.0E-06 TATTTATTTAGA 12 V_NRF1_Q6_M00652 TRANSFAC + 66586433 66586442 4.0E-06 CGCATGCGCG 10 V_NRF1_Q6_M00652 TRANSFAC - 66586461 66586470 2.0E-06 CGCATGCGCA 10 V_NRF1_Q6_M00652 TRANSFAC + 66586463 66586472 4.0E-06 CGCATGCGCG 10 V_FOX_Q2_M00809 TRANSFAC + 66583172 66583184 2.0E-06 CGTTATTTATTTA 13 V_STAT6_02_M00500 TRANSFAC - 66583723 66583730 1.0E-05 GATTTCCT 8 V_ZABC1_01_M01306 TRANSFAC + 66585258 66585265 1.0E-05 ATTCCAAC 8 V_ETS1_B_M00339 TRANSFAC + 66583549 66583563 1.0E-06 ACAGGAAATGGGTCG 15 V_ZFP281_01_M01597 TRANSFAC - 66583460 66583470 1.0E-06 TGGGGGAGGGG 11 V_OCT1_07_M00248 TRANSFAC + 66585294 66585305 5.0E-06 AGCATGTAAATT 12 V_ZFP281_04_M02831 TRANSFAC + 66583458 66583472 1.0E-05 CCCCCCTCCCCCACG 15 V_HFH3_01_M00289 TRANSFAC + 66583172 66583184 5.0E-06 CGTTATTTATTTA 13 V_FOXJ2_01_M00422 TRANSFAC - 66583170 66583187 1.0E-06 ATCTAAATAAATAACGTG 18 V_VDR_Q3_M00444 TRANSFAC - 66583455 66583469 8.0E-06 GGGGGAGGGGGGTTA 15 V_HNF3B_Q6_M02014 TRANSFAC + 66583174 66583182 1.0E-05 TTATTTATT 9 V_CMAF_01_M01070 TRANSFAC - 66585307 66585325 2.0E-06 ATTTTTGCTGAGTATGATG 19 V_TCF11MAFG_01_M00284 TRANSFAC - 66585507 66585528 1.0E-06 ACAAGATGAGGCAGCAGATCTA 22 V_TCF3_05_M02920 TRANSFAC + 66586632 66586646 0.0E+00 AGCCGAAAATAAAAC 15 V_FEV_01_M02269 TRANSFAC + 66583550 66583557 1.0E-05 CAGGAAAT 8 V_DEC_Q1_M00997 TRANSFAC + 66586673 66586685 4.0E-06 GGCCACGTGAAGA 13

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