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TGFA Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 7039 transforming growth factor, alpha chr2 - 70780647 - 70786147 70781147 Transcription Factor Binding Sites   Download all TFBS in the TGFA promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints MYBL2_MYB_DBD_dimeric_15_1 SELEX + 70784551 70784565 4.0E-06 AGCCGGTAAACCGCC 15 FOXA1_MA0148.1 JASPAR - 70784514 70784524 4.0E-06 TGTTTGCACAG 11 NHLH1_MA0048.1 JASPAR - 70780561 70780572 7.0E-06 CCGCAGCTGTGT 12 HNF1B_MA0153.1 JASPAR - 70778554 70778565 3.0E-06 TTAATGTTTGAT 12 RARG_nuclearreceptor_full_dimeric_17_1 SELEX + 70780580 70780596 6.0E-06 AAGTTCAAGCCCGTTCA 17 FOXD2_forkhead_DBD_dimeric_14_1 SELEX + 70778521 70778534 8.0E-06 TGAAAACATTAATC 14 FOXD2_forkhead_DBD_dimeric_14_1 SELEX - 70778521 70778534 6.0E-06 GATTAATGTTTTCA 14 Pax4_MA0068.1 JASPAR + 70778266 70778295 0.0E+00 AAATATATTCAACAACCCTATTAATATCCC 30 NR2F1_MA0017.1 JASPAR - 70780573 70780586 3.0E-06 TGAACTTTAATCCG 14 OTX1_homeodomain_DBD_monomeric_8_1 SELEX - 70780573 70780580 1.0E-05 TTAATCCG 8 FOXD3_forkhead_DBD_dimeric_14_1 SELEX - 70778521 70778534 4.0E-06 GATTAATGTTTTCA 14 HNF1A_homeodomain_full_dimeric_15_1 SELEX + 70778553 70778567 1.0E-06 AATCAAACATTAACC 15 Lhx3_MA0135.1 JASPAR + 70778526 70778538 6.0E-06 ACATTAATCAATG 13 RARG_nuclearreceptor_DBD_dimeric_17_1 SELEX + 70780580 70780596 8.0E-06 AAGTTCAAGCCCGTTCA 17 HNF1B_homeodomain_full_dimeric_13_1 SELEX - 70778554 70778566 2.0E-06 GTTAATGTTTGAT 13 Foxd3_MA0041.1 JASPAR - 70778553 70778564 3.0E-06 TAATGTTTGATT 12 HNF4A_MA0114.1 JASPAR + 70780574 70780586 4.0E-06 GGATTAAAGTTCA 13 HNF4A_nuclearreceptor_full_dimeric_14_1 SELEX + 70780573 70780586 6.0E-06 CGGATTAAAGTTCA 14 SPDEF_ETS_full_monomeric_11_1 SELEX - 70779692 70779702 9.0E-06 AACCGGATGCT 11 SPI1_ETS_full_monomeric_14_1 SELEX + 70780783 70780796 9.0E-06 GGAAAGGGGAACTC 14 IRF3_IRF_full_trimeric_21_1 SELEX - 70784571 70784591 0.0E+00 GGAGAAAGGAAAGGGAAAACT 21 HNF1B_homeodomain_full_dimeric_15_1 SELEX + 70778553 70778567 1.0E-06 AATCAAACATTAACC 15 Sox2_MA0143.1 JASPAR + 70780686 70780700 3.0E-06 TCTTTGTCATTCTTA 15 FOXC1_forkhead_DBD_dimeric_13_1 SELEX + 70778549 70778561 8.0E-06 AAGTAATCAAACA 13 RREB1_MA0073.1 JASPAR - 70781189 70781208 8.0E-06 ACCCCAAACCCCCACCCTCT 20 HNF1A_MA0046.1 JASPAR - 70778521 70778534 7.0E-06 GATTAATGTTTTCA 14 HNF1A_MA0046.1 JASPAR - 70778554 70778567 2.0E-06 GGTTAATGTTTGAT 14 V_FOXP1_01_M00987 TRANSFAC - 70778270 70778289 8.0E-06 TTAATAGGGTTGTTGAATAT 20 V_CEBPG_Q6_M00622 TRANSFAC + 70778670 70778682 5.0E-06 ACTATTTAAGAAA 13 V_AP2ALPHA_Q6_M01857 TRANSFAC - 70781525 70781535 9.0E-06 AGCCTCCAGCC 11 V_HNF3B_01_M00131 TRANSFAC - 70778552 70778566 1.0E-06 GTTAATGTTTGATTA 15 V_DBX1_01_M01483 TRANSFAC + 70778668 70778684 7.0E-06 CAACTATTTAAGAAAAA 17 V_TCF3_01_M01594 TRANSFAC + 70780686 70780698 8.0E-06 TCTTTGTCATTCT 13 V_HSF1_Q6_M01023 TRANSFAC - 70780771 70780787 4.0E-06 TTTCCGGGGGTTTCTGC 17 V_PAX4_03_M00378 TRANSFAC - 70781191 70781202 4.0E-06 AACCCCCACCCT 12 V_FOXD3_01_M00130 TRANSFAC - 70778553 70778564 2.0E-06 TAATGTTTGATT 12 V_ETS_B_M00340 TRANSFAC + 70781316 70781329 6.0E-06 GGCAGGAAGCGCCT 14 V_CEBP_C_M00201 TRANSFAC - 70779863 70779880 6.0E-06 AGTCTGTGGAAAGCCATG 18 V_HNF3_Q6_01_M01012 TRANSFAC - 70778549 70778566 6.0E-06 GTTAATGTTTGATTACTT 18 V_HNF4A_03_M02220 TRANSFAC + 70780574 70780586 4.0E-06 GGATTAAAGTTCA 13 V_GKLF_02_M01588 TRANSFAC - 70781250 70781261 5.0E-06 GCCCCGCCCAGC 12 V_NERF_Q2_M00531 TRANSFAC + 70781315 70781332 8.0E-06 AGGCAGGAAGCGCCTGAC 18 V_SP1_02_M01303 TRANSFAC + 70781211 70781221 8.0E-06 GGGGCGGGGAC 11 V_PSX1_01_M01435 TRANSFAC + 70778525 70778541 8.0E-06 AACATTAATCAATGCTC 17 V_CDX_Q5_M00991 TRANSFAC - 70779715 70779732 8.0E-06 TCCTGTAAGAGAAATACA 18 V_PAX_Q6_M00808 TRANSFAC - 70779664 70779674 6.0E-06 CTGAAACTCAC 11 V_NFY_C_M00209 TRANSFAC - 70784489 70784502 9.0E-06 TGTGATTGGCTTCT 14 V_LHX61_01_M01314 TRANSFAC + 70778524 70778540 1.0E-06 AAACATTAATCAATGCT 17 V_LHX61_01_M01314 TRANSFAC - 70778525 70778541 0.0E+00 GAGCATTGATTAATGTT 17 V_GFI1_01_M00250 TRANSFAC + 70778523 70778546 6.0E-06 AAAACATTAATCAATGCTCAGGTT 24 V_GFI1_01_M00250 TRANSFAC + 70784488 70784511 4.0E-06 GAGAAGCCAATCACAGCCTCTCCT 24 V_COUP_01_M00158 TRANSFAC - 70780573 70780586 3.0E-06 TGAACTTTAATCCG 14 V_HNF1_Q6_M00790 TRANSFAC - 70778551 70778568 4.0E-06 CGGTTAATGTTTGATTAC 18 V_HNF1B_04_M02266 TRANSFAC - 70778554 70778565 3.0E-06 TTAATGTTTGAT 12 V_E47_02_M00071 TRANSFAC + 70780610 70780625 5.0E-06 CTTCCCAGGTGTTCTC 16 V_IRF_Q6_M00772 TRANSFAC + 70784575 70784589 6.0E-06 TTCCCTTTCCTTTCT 15 V_PAX2_01_M00098 TRANSFAC + 70780687 70780705 6.0E-06 CTTTGTCATTCTTAATGAC 19 V_HNF1_Q6_01_M01011 TRANSFAC + 70778550 70778570 1.0E-06 AGTAATCAAACATTAACCGAG 21 V_OBOX2_01_M01364 TRANSFAC + 70780568 70780584 1.0E-05 TGCGGCGGATTAAAGTT 17 V_PAX5_01_M00143 TRANSFAC - 70781058 70781085 3.0E-06 CCGGCGGGCAGCGCTGCGGGGCGAGTGC 28 V_PBX1_01_M00096 TRANSFAC + 70778528 70778536 4.0E-06 ATTAATCAA 9 V_SP1SP3_Q4_M01219 TRANSFAC + 70781147 70781157 2.0E-06 CCCCCCCCTCC 11 V_RREB1_01_M00257 TRANSFAC - 70781194 70781207 0.0E+00 CCCCAAACCCCCAC 14 V_PNR_01_M01650 TRANSFAC + 70780573 70780586 7.0E-06 CGGATTAAAGTTCA 14 V_SP3_Q3_M00665 TRANSFAC - 70780608 70780621 6.0E-06 ACACCTGGGAAGGG 14 V_HIC1_02_M01072 TRANSFAC - 70781291 70781305 0.0E+00 CCCGGGTGCCCGGCT 15 V_HIC1_02_M01072 TRANSFAC - 70781465 70781479 5.0E-06 AACGGGTGCCCGGGC 15 V_NR1B1_Q6_M02110 TRANSFAC + 70780579 70780588 9.0E-06 AAAGTTCAAG 10 V_ISGF4G_04_M02875 TRANSFAC + 70778521 70778534 5.0E-06 TGAAAACATTAATC 14 V_FOXO1_Q5_M01216 TRANSFAC + 70778311 70778319 8.0E-06 AAAAACAAG 9 V_ELK1_01_M00007 TRANSFAC + 70781314 70781329 7.0E-06 AAGGCAGGAAGCGCCT 16 V_IRF7_01_M00453 TRANSFAC - 70784569 70784586 3.0E-06 AAGGAAAGGGAAAACTGA 18 V_ZFP691_04_M02937 TRANSFAC + 70778565 70778581 5.0E-06 ACCGAGACTCCTAACAG 17 V_BCL6B_04_M02844 TRANSFAC - 70781206 70781221 9.0E-06 GTCCCCGCCCCTTACC 16 V_BCL6B_04_M02844 TRANSFAC - 70781509 70781524 5.0E-06 TTCCCCGCCCCAGAGA 16 V_PTF1BETA_Q6_M00657 TRANSFAC - 70784565 70784578 3.0E-06 GGAAAACTGACAGG 14 V_ELF1_Q6_M00746 TRANSFAC + 70778374 70778385 5.0E-06 AGAGGAGGAAAT 12 V_HBP1_04_M02866 TRANSFAC + 70778290 70778306 2.0E-06 TATCCCCATTTTGCAGG 17 V_CAAT_01_M00254 TRANSFAC + 70784489 70784500 5.0E-06 AGAAGCCAATCA 12 V_MTF1_06_M02882 TRANSFAC + 70778673 70778686 0.0E+00 ATTTAAGAAAAATC 14 V_MAZR_01_M00491 TRANSFAC - 70781144 70781156 9.0E-06 GAGGGGGGGGTCA 13 V_NFYC_Q5_M02107 TRANSFAC + 70784491 70784504 0.0E+00 AAGCCAATCACAGC 14 V_OBOX2_02_M03064 TRANSFAC + 70780568 70780584 1.0E-05 TGCGGCGGATTAAAGTT 17 V_TAL1_01_M01591 TRANSFAC - 70778372 70778384 8.0E-06 TTTCCTCCTCTGT 13 V_IPF1_05_M01255 TRANSFAC + 70778524 70778535 5.0E-06 AAACATTAATCA 12 V_IPF1_05_M01255 TRANSFAC - 70780695 70780706 4.0E-06 AGTCATTAAGAA 12 V_HNF1_01_M00132 TRANSFAC - 70778520 70778534 8.0E-06 GATTAATGTTTTCAG 15 V_HNF1_01_M00132 TRANSFAC - 70778553 70778567 1.0E-06 GGTTAATGTTTGATT 15 V_CACBINDINGPROTEIN_Q6_M00720 TRANSFAC + 70781190 70781198 8.0E-06 GAGGGTGGG 9 V_BARHL1_01_M01332 TRANSFAC + 70778666 70778681 8.0E-06 TTCAACTATTTAAGAA 16 V_HEN1_02_M00058 TRANSFAC - 70781132 70781153 5.0E-06 GGGGGGGTCAGCTGTGCCCCGG 22 V_FOXJ3_06_M02855 TRANSFAC - 70784529 70784545 2.0E-06 TAGAGCATAACATAGTT 17 V_HNF4_Q6_01_M01031 TRANSFAC + 70780574 70780587 2.0E-06 GGATTAAAGTTCAA 14 V_ZBTB4_04_M02929 TRANSFAC - 70778417 70778432 5.0E-06 CCATCACTGGCAGGCA 16 V_NFY_01_M00287 TRANSFAC + 70784489 70784504 7.0E-06 AGAAGCCAATCACAGC 16 V_P53_04_M01652 TRANSFAC - 70780995 70781014 6.0E-06 GGGCAGGCCCTGCCTAGTCT 20 V_ETS1_B_M00339 TRANSFAC + 70781317 70781331 1.0E-05 GCAGGAAGCGCCTGA 15 V_MEF3_B_M00319 TRANSFAC + 70778537 70778549 5.0E-06 TGCTCAGGTTCCA 13 V_HSF_Q6_M00641 TRANSFAC - 70780774 70780786 4.0E-06 TTCCGGGGGTTTC 13 V_SOX2_01_M02246 TRANSFAC + 70780686 70780700 3.0E-06 TCTTTGTCATTCTTA 15 V_VDR_Q3_M00444 TRANSFAC + 70780808 70780822 1.0E-05 GGGGAAGCAGGGTGT 15 V_HNF1A_Q5_M02013 TRANSFAC - 70778557 70778567 1.0E-06 GGTTAATGTTT 11 V_IRF1_01_M00062 TRANSFAC - 70784565 70784577 5.0E-06 GAAAACTGACAGG 13 V_SP1_Q2_01_M00933 TRANSFAC - 70781210 70781219 7.0E-06 CCCCGCCCCT 10 V_RXRLXRB_01_M01198 TRANSFAC + 70780574 70780586 5.0E-06 GGATTAAAGTTCA 13 V_HNF4_01_M00134 TRANSFAC + 70780571 70780589 8.0E-06 GGCGGATTAAAGTTCAAGC 19 V_IPF1_04_M01236 TRANSFAC + 70778527 70778536 8.0E-06 CATTAATCAA 10 V_NFYA_Q5_M02106 TRANSFAC + 70784491 70784504 2.0E-06 AAGCCAATCACAGC 14 V_SP1_Q4_01_M00932 TRANSFAC + 70781209 70781221 5.0E-06 AAGGGGCGGGGAC 13 V_HNF1A_01_M02162 TRANSFAC - 70778521 70778534 7.0E-06 GATTAATGTTTTCA 14 V_HNF1A_01_M02162 TRANSFAC - 70778554 70778567 2.0E-06 GGTTAATGTTTGAT 14 V_PAX4_04_M00380 TRANSFAC + 70778266 70778295 3.0E-06 AAATATATTCAACAACCCTATTAATATCCC 30 V_NANOG_02_M01247 TRANSFAC - 70780681 70780700 4.0E-06 TAAGAATGACAAAGAGGGGA 20 V_HOXC9_01_M01416 TRANSFAC - 70780694 70780709 9.0E-06 GGGAGTCATTAAGAAT 16

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.