Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

SPINK2 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 6691 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) chr4 - 57687408 - 57693035 57687908 Transcription Factor Binding Sites   Download all TFBS in the SPINK2 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints RARB_nuclearreceptor_full_dimeric_16_1 SELEX + 57684608 57684623 4.0E-06 TGAGGTCAGGAGTTCA 16 SPIC_ETS_full_monomeric_14_1 SELEX + 57684331 57684344 3.0E-06 GAAATAAGGAAGAA 14 FOXG1_forkhead_DBD_dimeric_17_1 SELEX + 57684444 57684460 1.0E-06 TCAATTAGTTGTAAACA 17 POU5F1P1_POU_DBD_monomeric_9_1 SELEX + 57684277 57684285 4.0E-06 TATGCTAAT 9 FOXO3_MA0157.1 JASPAR + 57684453 57684460 7.0E-06 TGTAAACA 8 POU2F3_POU_DBD_monomeric_9_1 SELEX + 57684277 57684285 3.0E-06 TATGCTAAT 9 EWSR1-FLI1_MA0149.1 JASPAR + 57684330 57684347 2.0E-06 GGAAATAAGGAAGAAAAA 18 RARA_nuclearreceptor_DBD_dimeric_18_2 SELEX + 57684609 57684626 2.0E-06 GAGGTCAGGAGTTCAAGA 18 POU3F4_POU_DBD_monomeric_9_1 SELEX + 57684277 57684285 3.0E-06 TATGCTAAT 9 Pou2f2_POU_DBD_monomeric_9_1 SELEX + 57684277 57684285 3.0E-06 TATGCTAAT 9 Pax4_MA0068.1 JASPAR - 57691508 57691537 3.0E-06 AAAAAAAAAAAAAGAATACAGTTATGCCCA 30 RORA_nuclearreceptor_DBD_dimeric_19_1 SELEX + 57685648 57685666 2.0E-06 TAACCAGGCCAGGAGGCCA 19 POU3F3_POU_DBD_monomeric_13_1 SELEX + 57684275 57684287 7.0E-06 ACTATGCTAATCT 13 ELF3_ETS_full_monomeric_13_1 SELEX + 57684218 57684230 8.0E-06 TAGCAGGAAGTGG 13 SP1_MA0079.2 JASPAR + 57688133 57688142 3.0E-06 CCCCTCCCCC 10 SRY_MA0084.1 JASPAR + 57684511 57684519 5.0E-06 TTTAACAAT 9 SP4_C2H2_full_monomeric_17_1 SELEX - 57687920 57687936 5.0E-06 CTCGCCCCGCCCCTTCC 17 NR2F1_nuclearreceptor_DBD_dimeric_16_1 SELEX + 57684609 57684624 1.0E-06 GAGGTCAGGAGTTCAA 16 ELK1_MA0028.1 JASPAR + 57688026 57688035 1.0E-06 GAACCGGAAA 10 JDP2_bZIP_full_dimeric_9_1 SELEX - 57684499 57684507 7.0E-06 ATGACTCAC 9 POU2F1_POU_DBD_monomeric_12_1 SELEX + 57684275 57684286 6.0E-06 ACTATGCTAATC 12 Nr2f6_nuclearreceptor_DBD_dimeric_15_1 SELEX + 57684609 57684623 0.0E+00 GAGGTCAGGAGTTCA 15 RARG_nuclearreceptor_full_dimeric_16_1 SELEX + 57684609 57684624 2.0E-06 GAGGTCAGGAGTTCAA 16 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 57691525 57691537 6.0E-06 AAAAAAAAAAAAA 13 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 57691526 57691538 6.0E-06 AAAAAAAAAAAAA 13 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 57691527 57691539 6.0E-06 AAAAAAAAAAAAA 13 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 57691528 57691540 6.0E-06 AAAAAAAAAAAAA 13 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 57691529 57691541 6.0E-06 AAAAAAAAAAAAA 13 NFE2L2_MA0150.1 JASPAR - 57691554 57691564 2.0E-06 GTGACACAGCA 11 RARA_nuclearreceptor_full_dimeric_15_1 SELEX + 57684609 57684623 5.0E-06 GAGGTCAGGAGTTCA 15 V_FOXP1_01_M00987 TRANSFAC + 57691513 57691532 2.0E-06 ATAACTGTATTCTTTTTTTT 20 V_FOXP1_01_M00987 TRANSFAC + 57691519 57691538 1.0E-06 GTATTCTTTTTTTTTTTTTT 20 V_FOXP1_01_M00987 TRANSFAC + 57691521 57691540 5.0E-06 ATTCTTTTTTTTTTTTTTTT 20 V_FOXP1_01_M00987 TRANSFAC + 57691522 57691541 0.0E+00 TTCTTTTTTTTTTTTTTTTT 20 V_TCF3_01_M01594 TRANSFAC + 57691523 57691535 7.0E-06 TCTTTTTTTTTTT 13 V_APOLYA_B_M00310 TRANSFAC + 57688235 57688249 0.0E+00 AATCAACACCTATTT 15 V_FOXO3_02_M02270 TRANSFAC + 57684453 57684460 7.0E-06 TGTAAACA 8 V_BACH2_01_M00490 TRANSFAC + 57684498 57684508 4.0E-06 TGTGAGTCATC 11 V_ATF5_01_M01295 TRANSFAC - 57684335 57684345 1.0E-06 TTTCTTCCTTA 11 V_ATF5_01_M01295 TRANSFAC + 57684369 57684379 5.0E-06 TCTCTCCCTTT 11 V_HMGIY_Q3_M01010 TRANSFAC + 57691520 57691534 5.0E-06 TATTCTTTTTTTTTT 15 V_HMGIY_Q3_M01010 TRANSFAC + 57691694 57691708 5.0E-06 TCTTGTATTTTTTGT 15 V_EVI1_04_M00081 TRANSFAC - 57691520 57691534 7.0E-06 AAAAAAAAAAGAATA 15 V_EVI1_04_M00081 TRANSFAC - 57691525 57691539 6.0E-06 AAAAAAAAAAAAAAA 15 V_EVI1_04_M00081 TRANSFAC - 57691526 57691540 6.0E-06 AAAAAAAAAAAAAAA 15 V_EVI1_04_M00081 TRANSFAC - 57691527 57691541 6.0E-06 AAAAAAAAAAAAAAA 15 V_BCL6_01_M01183 TRANSFAC + 57691520 57691535 2.0E-06 TATTCTTTTTTTTTTT 16 V_BCL6_01_M01183 TRANSFAC + 57691521 57691536 7.0E-06 ATTCTTTTTTTTTTTT 16 V_BCL6_01_M01183 TRANSFAC + 57691523 57691538 9.0E-06 TCTTTTTTTTTTTTTT 16 V_BCL6_01_M01183 TRANSFAC + 57691524 57691539 2.0E-06 CTTTTTTTTTTTTTTT 16 V_BCL6_01_M01183 TRANSFAC + 57691525 57691540 0.0E+00 TTTTTTTTTTTTTTTT 16 V_BCL6_01_M01183 TRANSFAC + 57691526 57691541 0.0E+00 TTTTTTTTTTTTTTTT 16 V_BCL6_01_M01183 TRANSFAC + 57691691 57691706 2.0E-06 TATTCTTGTATTTTTT 16 V_SP1_Q6_01_M00931 TRANSFAC + 57687924 57687933 4.0E-06 GGGGCGGGGC 10 V_OCT1_Q5_01_M00930 TRANSFAC - 57684327 57684337 4.0E-06 TTATTTCCATT 11 V_OCT1_01_M00135 TRANSFAC + 57684272 57684290 7.0E-06 GCCACTATGCTAATCTAGG 19 V_POU2F3_01_M01476 TRANSFAC + 57684274 57684289 9.0E-06 CACTATGCTAATCTAG 16 V_SOX11_04_M02899 TRANSFAC - 57684509 57684522 9.0E-06 AAGATTGTTAAAAG 14 V_HNF3_Q6_01_M01012 TRANSFAC + 57691522 57691539 9.0E-06 TTCTTTTTTTTTTTTTTT 18 V_SP1_03_M02281 TRANSFAC + 57688133 57688142 3.0E-06 CCCCTCCCCC 10 V_STAT6_01_M00494 TRANSFAC - 57684329 57684336 7.0E-06 TATTTCCA 8 V_GKLF_02_M01588 TRANSFAC + 57691676 57691687 3.0E-06 ACCACACCCAGC 12 V_PITX2_Q6_M02114 TRANSFAC - 57686048 57686057 1.0E-06 TGTAATCCCA 10 V_CACCCBINDINGFACTOR_Q6_M00721 TRANSFAC - 57691677 57691692 5.0E-06 TATTAGCTGGGTGTGG 16 V_PU1_Q4_M01172 TRANSFAC - 57684217 57684235 5.0E-06 ACTTTCCACTTCCTGCTAC 19 V_PU1_Q4_M01172 TRANSFAC - 57684332 57684350 1.0E-06 TGGTTTTTCTTCCTTATTT 19 V_NFAT2_01_M01748 TRANSFAC + 57684328 57684336 6.0E-06 ATGGAAATA 9 V_TCFAP2E_04_M02926 TRANSFAC - 57691523 57691536 6.0E-06 AAAAAAAAAAAAGA 14 V_TCFAP2E_04_M02926 TRANSFAC - 57691524 57691537 4.0E-06 AAAAAAAAAAAAAG 14 V_TCFAP2E_04_M02926 TRANSFAC - 57691525 57691538 1.0E-06 AAAAAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC - 57691526 57691539 1.0E-06 AAAAAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC - 57691527 57691540 1.0E-06 AAAAAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC - 57691528 57691541 1.0E-06 AAAAAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC - 57691529 57691542 2.0E-06 CAAAAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC - 57691530 57691543 3.0E-06 TCAAAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC - 57691531 57691544 2.0E-06 CTCAAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC - 57691533 57691546 1.0E-06 CTCTCAAAAAAAAA 14 V_LXRB_RXRA_Q5_M02021 TRANSFAC + 57684608 57684622 2.0E-06 TGAGGTCAGGAGTTC 15 V_AP1_Q6_M00174 TRANSFAC - 57684498 57684508 1.0E-05 GATGACTCACA 11 V_RPC155_01_M01798 TRANSFAC + 57684613 57684628 0.0E+00 TCAGGAGTTCAAGACC 16 V_ETS_Q4_M00771 TRANSFAC - 57684221 57684232 2.0E-06 TTCCACTTCCTG 12 V_ELF4_04_M02850 TRANSFAC - 57691525 57691541 6.0E-06 AAAAAAAAAAAAAAAAA 17 V_ELF4_04_M02850 TRANSFAC - 57691527 57691543 2.0E-06 TCAAAAAAAAAAAAAAA 17 V_ELF4_04_M02850 TRANSFAC - 57691528 57691544 3.0E-06 CTCAAAAAAAAAAAAAA 17 V_ELF4_04_M02850 TRANSFAC - 57691529 57691545 0.0E+00 TCTCAAAAAAAAAAAAA 17 V_ELF4_04_M02850 TRANSFAC - 57691530 57691546 9.0E-06 CTCTCAAAAAAAAAAAA 17 V_ELF4_04_M02850 TRANSFAC - 57691531 57691547 7.0E-06 TCTCTCAAAAAAAAAAA 17 V_BACH1_01_M00495 TRANSFAC + 57684496 57684510 7.0E-06 TGTGTGAGTCATCCT 15 V_GC_01_M00255 TRANSFAC + 57687922 57687935 5.0E-06 AAGGGGCGGGGCGA 14 V_ZFP105_03_M02827 TRANSFAC - 57691522 57691536 0.0E+00 AAAAAAAAAAAAGAA 15 V_ZFP105_03_M02827 TRANSFAC - 57691523 57691537 1.0E-06 AAAAAAAAAAAAAGA 15 V_ZFP105_03_M02827 TRANSFAC - 57691524 57691538 0.0E+00 AAAAAAAAAAAAAAG 15 V_ZFP105_03_M02827 TRANSFAC - 57691525 57691539 0.0E+00 AAAAAAAAAAAAAAA 15 V_ZFP105_03_M02827 TRANSFAC - 57691526 57691540 0.0E+00 AAAAAAAAAAAAAAA 15 V_ZFP105_03_M02827 TRANSFAC - 57691527 57691541 0.0E+00 AAAAAAAAAAAAAAA 15 V_ZFP105_03_M02827 TRANSFAC - 57691528 57691542 1.0E-06 CAAAAAAAAAAAAAA 15 V_ZFP105_03_M02827 TRANSFAC - 57691529 57691543 2.0E-06 TCAAAAAAAAAAAAA 15 V_ZFP105_03_M02827 TRANSFAC - 57691530 57691544 1.0E-06 CTCAAAAAAAAAAAA 15 V_CART1_01_M00416 TRANSFAC - 57684323 57684340 9.0E-06 TCCTTATTTCCATTGCCA 18 V_GFI1_01_M00250 TRANSFAC + 57684421 57684444 5.0E-06 AACAGAGAAATCTGTGGTTGTGAT 24 V_OLF1_01_M00261 TRANSFAC - 57687627 57687648 4.0E-06 GGCGGTTCCCCAGAGGACCTGC 22 V_SP1_Q6_M00196 TRANSFAC + 57687922 57687934 1.0E-06 AAGGGGCGGGGCG 13 V_LEF1_03_M02878 TRANSFAC + 57684350 57684365 6.0E-06 AAAGATCAATCTCTCT 16 V_ELF5_01_M01197 TRANSFAC + 57684334 57684344 8.0E-06 ATAAGGAAGAA 11 V_JUNDM2_04_M02876 TRANSFAC + 57684495 57684510 9.0E-06 TTGTGTGAGTCATCCT 16 V_JUNDM2_04_M02876 TRANSFAC - 57684496 57684511 0.0E+00 AAGGATGACTCACACA 16 V_HOX13_01_M00023 TRANSFAC + 57684434 57684463 8.0E-06 GTGGTTGTGATCAATTAGTTGTAAACACCA 30 V_HOX13_01_M00023 TRANSFAC + 57685624 57685653 6.0E-06 AGGAACCCAAACCATTATTTAGAATAACCA 30 V_SPIB_01_M01204 TRANSFAC + 57684331 57684347 8.0E-06 GAAATAAGGAAGAAAAA 17 V_TEL2_Q6_M00678 TRANSFAC - 57684221 57684230 6.0E-06 CCACTTCCTG 10 V_GATA5_04_M02860 TRANSFAC + 57684421 57684437 7.0E-06 AACAGAGAAATCTGTGG 17 V_TCF1_07_M02919 TRANSFAC - 57684280 57684293 4.0E-06 TTACCTAGATTAGC 14 V_AP1_01_M00517 TRANSFAC + 57684497 57684509 6.0E-06 GTGTGAGTCATCC 13 V_GATA4_Q3_M00632 TRANSFAC - 57684373 57684384 0.0E+00 AGAAAAAAGGGA 12 V_NEUROD_02_M01288 TRANSFAC - 57686073 57686084 6.0E-06 TTGCAGCTGGGC 12 V_SP4_Q5_M01273 TRANSFAC - 57687923 57687933 8.0E-06 GCCCCGCCCCT 11 V_EN2_01_M01455 TRANSFAC - 57684193 57684209 9.0E-06 TGCTTCAATTAGTCTCT 17 V_AP1_Q4_01_M00926 TRANSFAC + 57684500 57684507 1.0E-05 TGAGTCAT 8 V_CIZ_01_M00734 TRANSFAC - 57691699 57691707 6.0E-06 CAAAAAATA 9 V_MTF1_06_M02882 TRANSFAC - 57684376 57684389 4.0E-06 TCTTAAGAAAAAAG 14 V_MTF1_06_M02882 TRANSFAC - 57691523 57691536 3.0E-06 AAAAAAAAAAAAGA 14 V_MTF1_06_M02882 TRANSFAC - 57691524 57691537 1.0E-06 AAAAAAAAAAAAAG 14 V_MTF1_06_M02882 TRANSFAC - 57691525 57691538 1.0E-06 AAAAAAAAAAAAAA 14 V_MTF1_06_M02882 TRANSFAC - 57691526 57691539 1.0E-06 AAAAAAAAAAAAAA 14 V_MTF1_06_M02882 TRANSFAC - 57691527 57691540 1.0E-06 AAAAAAAAAAAAAA 14 V_MTF1_06_M02882 TRANSFAC - 57691528 57691541 1.0E-06 AAAAAAAAAAAAAA 14 V_MTF1_06_M02882 TRANSFAC - 57691529 57691542 8.0E-06 CAAAAAAAAAAAAA 14 V_FAC1_01_M00456 TRANSFAC - 57691522 57691535 8.0E-06 AAAAAAAAAAAGAA 14 V_FAC1_01_M00456 TRANSFAC - 57691525 57691538 3.0E-06 AAAAAAAAAAAAAA 14 V_FAC1_01_M00456 TRANSFAC - 57691526 57691539 3.0E-06 AAAAAAAAAAAAAA 14 V_FAC1_01_M00456 TRANSFAC - 57691527 57691540 3.0E-06 AAAAAAAAAAAAAA 14 V_FAC1_01_M00456 TRANSFAC - 57691528 57691541 3.0E-06 AAAAAAAAAAAAAA 14 V_EOMES_04_M02851 TRANSFAC - 57688234 57688249 9.0E-06 AAATAGGTGTTGATTG 16 V_OCT2_01_M01368 TRANSFAC + 57684274 57684289 6.0E-06 CACTATGCTAATCTAG 16 V_GATA3_02_M00350 TRANSFAC + 57684293 57684302 1.0E-05 AGAGATAATG 10 V_PARP_Q3_M01211 TRANSFAC - 57688244 57688253 1.0E-06 TAAGAAATAG 10 V_TCF7L2_04_M02922 TRANSFAC + 57684350 57684365 7.0E-06 AAAGATCAATCTCTCT 16 V_BDP1_01_M01796 TRANSFAC - 57684617 57684628 2.0E-06 GGTCTTGAACTC 12 V_FRA1_Q5_M01267 TRANSFAC + 57684500 57684507 1.0E-05 TGAGTCAT 8 V_FPM315_01_M01587 TRANSFAC - 57687828 57687839 6.0E-06 GCGGGAGGAGGA 12 V_ASCL2_04_M02841 TRANSFAC - 57684245 57684260 1.0E-06 TTTTCCCCATCCTTTT 16 V_PITX2_Q2_M00482 TRANSFAC - 57686047 57686057 1.0E-06 TGTAATCCCAG 11 V_ZFP281_01_M01597 TRANSFAC - 57688133 57688143 2.0E-06 GGGGGGAGGGG 11 V_PBX_Q3_M00998 TRANSFAC - 57684349 57684360 7.0E-06 GATTGATCTTTG 12 V_ZFP281_04_M02831 TRANSFAC + 57688131 57688145 3.0E-06 TTCCCCTCCCCCCAA 15 V_SRF_06_M02916 TRANSFAC - 57691520 57691536 9.0E-06 AAAAAAAAAAAAGAATA 17 V_SRF_06_M02916 TRANSFAC - 57691521 57691537 0.0E+00 AAAAAAAAAAAAAGAAT 17 V_SRF_06_M02916 TRANSFAC - 57691522 57691538 0.0E+00 AAAAAAAAAAAAAAGAA 17 V_SRF_06_M02916 TRANSFAC - 57691523 57691539 0.0E+00 AAAAAAAAAAAAAAAGA 17 V_SRF_06_M02916 TRANSFAC - 57691524 57691540 1.0E-06 AAAAAAAAAAAAAAAAG 17 V_SRF_06_M02916 TRANSFAC - 57691525 57691541 0.0E+00 AAAAAAAAAAAAAAAAA 17 V_SRF_06_M02916 TRANSFAC - 57691526 57691542 0.0E+00 CAAAAAAAAAAAAAAAA 17 V_SRF_06_M02916 TRANSFAC - 57691527 57691543 0.0E+00 TCAAAAAAAAAAAAAAA 17 V_SRF_06_M02916 TRANSFAC - 57691528 57691544 0.0E+00 CTCAAAAAAAAAAAAAA 17 V_SRF_06_M02916 TRANSFAC - 57691529 57691545 0.0E+00 TCTCAAAAAAAAAAAAA 17 V_SRF_06_M02916 TRANSFAC - 57691530 57691546 4.0E-06 CTCTCAAAAAAAAAAAA 17 V_EWSR1FLI1_01_M02252 TRANSFAC + 57684330 57684347 2.0E-06 GGAAATAAGGAAGAAAAA 18 V_SATB1_01_M01232 TRANSFAC - 57685638 57685649 9.0E-06 TATTCTAAATAA 12 V_EKLF_Q5_M01874 TRANSFAC + 57691677 57691686 5.0E-06 CCACACCCAG 10 V_PIT1_Q6_M00802 TRANSFAC - 57684329 57684346 6.0E-06 TTTTCTTCCTTATTTCCA 18 V_SP1_Q2_01_M00933 TRANSFAC - 57687923 57687932 7.0E-06 CCCCGCCCCT 10 V_ARP1_01_M00155 TRANSFAC - 57684608 57684623 1.0E-06 TGAACTCCTGACCTCA 16 V_NFE2L2_01_M02263 TRANSFAC - 57691554 57691564 2.0E-06 GTGACACAGCA 11 V_UF1H3BETA_Q6_M01068 TRANSFAC + 57687914 57687927 4.0E-06 GGCGGGGGAAGGGG 14 V_MAFK_04_M02880 TRANSFAC - 57691694 57691708 2.0E-06 ACAAAAAATACAAGA 15 V_SOX5_07_M02909 TRANSFAC - 57684509 57684525 6.0E-06 GACAAGATTGTTAAAAG 17 V_GATA1_02_M00126 TRANSFAC + 57684291 57684304 5.0E-06 TAAGAGATAATGGG 14 V_SP1_Q4_01_M00932 TRANSFAC + 57687922 57687934 1.0E-06 AAGGGGCGGGGCG 13 V_TAACC_B_M00331 TRANSFAC + 57684469 57684491 0.0E+00 CAAAAACCAGCCAAACCAAAGAT 23 V_TCF11MAFG_01_M00284 TRANSFAC - 57691548 57691569 9.0E-06 CCTGGGTGACACAGCAAGATCT 22 V_TCF3_05_M02920 TRANSFAC - 57691531 57691545 4.0E-06 TCTCAAAAAAAAAAA 15 V_EVI1_03_M00080 TRANSFAC - 57684516 57684526 7.0E-06 TGACAAGATTG 11 V_PAX4_04_M00380 TRANSFAC - 57691507 57691536 7.0E-06 AAAAAAAAAAAAGAATACAGTTATGCCCAT 30 V_NANOG_02_M01247 TRANSFAC - 57691514 57691533 6.0E-06 AAAAAAAAAGAATACAGTTA 20 V_NANOG_02_M01247 TRANSFAC - 57691519 57691538 8.0E-06 AAAAAAAAAAAAAAGAATAC 20 V_NANOG_02_M01247 TRANSFAC - 57691522 57691541 4.0E-06 AAAAAAAAAAAAAAAAAGAA 20 V_NANOG_02_M01247 TRANSFAC - 57691524 57691543 5.0E-06 TCAAAAAAAAAAAAAAAAAG 20

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.