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AEN Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 64782 apoptosis enhancing nuclease chr15 + 89159526 - 89165026 89164526 Transcription Factor Binding Sites   Download all TFBS in the AEN promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints POU4F2_POU_full_monomeric_16_1 SELEX + 89168196 89168211 3.0E-06 TGGCATAACAAATGAG 16 MSX2_homeodomain_DBD_dimeric_18_1 SELEX - 89165665 89165682 5.0E-06 CTGATTAAAAGCCAATTC 18 HOXC13_homeodomain_DBD_monomeric_11_1 SELEX - 89165770 89165780 4.0E-06 TCTTGTAAAAT 11 SPIC_ETS_full_monomeric_14_1 SELEX + 89166428 89166441 3.0E-06 AATATGAGGAAGTT 14 BARX1_homeodomain_DBD_dimeric_17_1 SELEX - 89165665 89165681 7.0E-06 TGATTAAAAGCCAATTC 17 POU3F3_POU_DBD_monomeric_12_1 SELEX - 89166582 89166593 4.0E-06 TTGCATAAAGAA 12 RARA_nuclearreceptor_full_dimeric_18_1 SELEX - 89164726 89164743 4.0E-06 CAGGGTCAGCCCAGTTCA 18 FOXG1_forkhead_DBD_dimeric_17_1 SELEX - 89165499 89165515 2.0E-06 TTCAACAAGGACAAACA 17 POU3F2_POU_DBD_monomeric_13_1 SELEX - 89166582 89166594 1.0E-06 TTTGCATAAAGAA 13 POU5F1P1_POU_DBD_monomeric_9_1 SELEX + 89166587 89166595 2.0E-06 TATGCAAAT 9 SOX8_HMG_DBD_dimeric_16_1 SELEX - 89165760 89165775 2.0E-06 TAAAATCTTTAGTGTT 16 SOX9_HMG_full_dimeric_17_3 SELEX + 89168270 89168286 7.0E-06 CATGAACATCAGACATT 17 POU3F4_POU_DBD_monomeric_11_1 SELEX - 89166582 89166592 7.0E-06 TGCATAAAGAA 11 Tp53_p53l_DBD_dimeric_18_2 SELEX + 89164538 89164555 1.0E-06 GGCTTGCCCGGGCATGTG 18 Tp53_p53l_DBD_dimeric_18_2 SELEX - 89164538 89164555 0.0E+00 CACATGCCCGGGCAAGCC 18 SRY_HMG_DBD_dimeric_16_1 SELEX - 89165760 89165775 8.0E-06 TAAAATCTTTAGTGTT 16 POU2F3_POU_DBD_monomeric_9_1 SELEX + 89166587 89166595 2.0E-06 TATGCAAAT 9 HOXD13_homeodomain_DBD_monomeric_11_1 SELEX - 89165770 89165780 5.0E-06 TCTTGTAAAAT 11 RARG_nuclearreceptor_full_dimeric_17_1 SELEX - 89164726 89164742 5.0E-06 AGGGTCAGCCCAGTTCA 17 POU1F1_POU_DBD_monomeric_14_1 SELEX + 89166585 89166598 3.0E-06 TTTATGCAAATGCT 14 Rarb_nuclearreceptor_DBD_dimeric_18_1 SELEX - 89164726 89164743 2.0E-06 CAGGGTCAGCCCAGTTCA 18 NFYA_MA0060.1 JASPAR + 89164467 89164482 0.0E+00 CTCGACCAATCAGAAG 16 POU2F2_POU_DBD_monomeric_11_1 SELEX + 89166586 89166596 1.0E-06 TTATGCAAATG 11 MAFF_bZIP_DBD_dimeric_15_1 SELEX - 89165606 89165620 9.0E-06 ATGCTGACACGTCAA 15 POU3F4_POU_DBD_monomeric_9_1 SELEX + 89166587 89166595 2.0E-06 TATGCAAAT 9 Pou2f2_POU_DBD_monomeric_9_1 SELEX + 89166587 89166595 2.0E-06 TATGCAAAT 9 E2F7_E2F_DBD_dimeric_14_1 SELEX + 89164371 89164384 1.0E-06 ATTTCCCGCCAGTA 14 SPIB_ETS_DBD_monomeric_14_1 SELEX + 89166428 89166441 1.0E-06 AATATGAGGAAGTT 14 IRF1_MA0050.1 JASPAR + 89167787 89167798 1.0E-06 AAAACTGAAACT 12 POU3F3_POU_DBD_monomeric_13_1 SELEX + 89166585 89166597 4.0E-06 TTTATGCAAATGC 13 RARG_nuclearreceptor_DBD_dimeric_17_2 SELEX - 89164726 89164742 1.0E-06 AGGGTCAGCCCAGTTCA 17 NR2E1_nuclearreceptor_full_dimeric_14_1 SELEX - 89165362 89165375 2.0E-06 GAACCAAGAAGTCA 14 FOXO4_forkhead_DBD_putatively-multimeric_12_1 SELEX - 89166572 89166583 8.0E-06 AATCCCCACACT 12 HIC2_C2H2_DBD_monomeric_9_1 SELEX - 89166336 89166344 1.0E-05 ATGCCCACC 9 MAFK_bZIP_DBD_dimeric_21_1 SELEX - 89165603 89165623 8.0E-06 TACATGCTGACACGTCAAAAC 21 PBX1_MA0070.1 JASPAR - 89165787 89165798 4.0E-06 CAATCAATCATG 12 RARG_nuclearreceptor_DBD_dimeric_17_1 SELEX - 89164726 89164742 2.0E-06 AGGGTCAGCCCAGTTCA 17 Mycn_MA0104.2 JASPAR - 89164577 89164586 9.0E-06 TGCACGTGGC 10 Msx3_homeodomain_DBD_dimeric_18_1 SELEX - 89165665 89165682 3.0E-06 CTGATTAAAAGCCAATTC 18 POU1F1_POU_DBD_monomeric_17_1 SELEX - 89166580 89166596 7.0E-06 CATTTGCATAAAGAATC 17 POU3F1_POU_DBD_monomeric_12_1 SELEX + 89166586 89166597 1.0E-06 TTATGCAAATGC 12 IRF9_IRF_full_trimeric_15_1 SELEX + 89167784 89167798 5.0E-06 CTGAAAACTGAAACT 15 POU3F1_POU_DBD_monomeric_12_2 SELEX - 89166582 89166593 6.0E-06 TTGCATAAAGAA 12 FEV_MA0156.1 JASPAR - 89168284 89168291 1.0E-05 CAGGAAAT 8 MAFG_bZIP_full_dimeric_21_1 SELEX + 89165603 89165623 6.0E-06 GTTTTGACGTGTCAGCATGTA 21 MAFG_bZIP_full_dimeric_21_1 SELEX - 89165603 89165623 6.0E-06 TACATGCTGACACGTCAAAAC 21 HOXB13_homeodomain_DBD_monomeric_11_1 SELEX - 89165770 89165780 8.0E-06 TCTTGTAAAAT 11 TFAP4_bHLH_full_dimeric_10_1 SELEX - 89168233 89168242 9.0E-06 AACAGCTGAG 10 Pou5f1_MA0142.1 JASPAR - 89165699 89165713 5.0E-06 TTTTGAGATGCTAGT 15 HOXA13_homeodomain_full_monomeric_11_1 SELEX - 89165770 89165780 2.0E-06 TCTTGTAAAAT 11 SOX21_HMG_DBD_dimeric_16_1 SELEX - 89165760 89165775 3.0E-06 TAAAATCTTTAGTGTT 16 POU2F1_POU_DBD_monomeric_12_1 SELEX + 89166585 89166596 1.0E-06 TTTATGCAAATG 12 IRF4_IRF_full_dimeric_15_1 SELEX + 89167785 89167799 9.0E-06 TGAAAACTGAAACTT 15 Mafb_bZIP_DBD_dimeric_18_1 SELEX + 89166593 89166610 5.0E-06 AATGCTGGCATCATCAAA 18 Mafb_bZIP_DBD_dimeric_18_1 SELEX - 89166593 89166610 1.0E-06 TTTGATGATGCCAGCATT 18 SPI1_ETS_full_monomeric_14_1 SELEX + 89166428 89166441 1.0E-06 AATATGAGGAAGTT 14 TP53_MA0106.1 JASPAR + 89164535 89164554 0.0E+00 CCGGGCTTGCCCGGGCATGT 20 FOXO1_forkhead_DBD_putatively-multimeric_12_1 SELEX - 89166572 89166583 7.0E-06 AATCCCCACACT 12 POU3F2_POU_DBD_monomeric_12_1 SELEX + 89166586 89166597 1.0E-06 TTATGCAAATGC 12 MSX1_homeodomain_DBD_dimeric_18_1 SELEX - 89165665 89165682 2.0E-06 CTGATTAAAAGCCAATTC 18 Sox2_MA0143.1 JASPAR + 89166474 89166488 8.0E-06 CTTTTCTCCTGGAAA 15 Sox2_MA0143.1 JASPAR - 89168195 89168209 2.0E-06 CATTTGTTATGCCAA 15 V_SPI1_01_M01203 TRANSFAC + 89166428 89166444 1.0E-06 AATATGAGGAAGTTGGT 17 V_ZSCAN4_03_M02838 TRANSFAC - 89165722 89165738 8.0E-06 AAACTGTGCACTCAACA 17 V_LEF1_04_M02774 TRANSFAC + 89168160 89168176 7.0E-06 AGTTTGTTTGATCTGTT 17 V_APOLYA_B_M00310 TRANSFAC - 89165665 89165679 1.0E-06 ATTAAAAGCCAATTC 15 V_POU3F3_01_M03090 TRANSFAC - 89166582 89166598 3.0E-06 AGCATTTGCATAAAGAA 17 V_DUXL_01_M01390 TRANSFAC - 89165787 89165803 3.0E-06 TTGCTCAATCAATCATG 17 V_ZFX_01_M01593 TRANSFAC - 89164700 89164715 3.0E-06 CCGCAGGCCGGGGCGG 16 V_BCL6_01_M01183 TRANSFAC - 89165767 89165782 3.0E-06 TTTCTTGTAAAATCTT 16 V_ETS_B_M00340 TRANSFAC - 89168280 89168293 1.0E-06 TACAGGAAATGTCT 14 V_GATA3_03_M00351 TRANSFAC + 89165766 89165775 3.0E-06 AAAGATTTTA 10 V_POU5F1_02_M02245 TRANSFAC - 89165699 89165713 5.0E-06 TTTTGAGATGCTAGT 15 V_MAFB_03_M02879 TRANSFAC - 89166582 89166596 6.0E-06 CATTTGCATAAAGAA 15 V_OCT1_Q5_01_M00930 TRANSFAC - 89166587 89166597 8.0E-06 GCATTTGCATA 11 V_DR4_Q2_M00965 TRANSFAC + 89164726 89164742 6.0E-06 TGAACTGGGCTGACCCT 17 V_OCTAMER_01_M01324 TRANSFAC - 89166582 89166598 3.0E-06 AGCATTTGCATAAAGAA 17 V_IRF_Q6_01_M00972 TRANSFAC + 89167787 89167797 1.0E-06 AAAACTGAAAC 11 V_IRF2_Q6_M01882 TRANSFAC + 89167785 89167800 1.0E-06 TGAAAACTGAAACTTA 16 V_OCT1_01_M00135 TRANSFAC + 89166582 89166600 0.0E+00 TTCTTTATGCAAATGCTGG 19 V_POU2F3_01_M01476 TRANSFAC + 89166584 89166599 1.0E-06 CTTTATGCAAATGCTG 16 V_AP4_Q6_M00176 TRANSFAC + 89168233 89168242 8.0E-06 CTCAGCTGTT 10 V_IRF3_05_M02767 TRANSFAC + 89167786 89167799 8.0E-06 GAAAACTGAAACTT 14 V_HNF3_Q6_01_M01012 TRANSFAC + 89168159 89168176 7.0E-06 TAGTTTGTTTGATCTGTT 18 V_OCT_C_M00210 TRANSFAC - 89166586 89166598 3.0E-06 AGCATTTGCATAA 13 V_PU1_Q4_M01172 TRANSFAC - 89166429 89166447 5.0E-06 GTAACCAACTTCCTCATAT 19 V_NFY_Q6_01_M00775 TRANSFAC + 89164466 89164478 2.0E-06 GCTCGACCAATCA 13 V_BRN2_01_M00145 TRANSFAC - 89167769 89167784 7.0E-06 GGCATGTAAAATGATC 16 V_HOXA13_03_M01430 TRANSFAC - 89165768 89165783 4.0E-06 CTTTCTTGTAAAATCT 16 V_HOXC13_01_M01317 TRANSFAC - 89165768 89165783 2.0E-06 CTTTCTTGTAAAATCT 16 V_CEBPB_01_M00109 TRANSFAC + 89165793 89165806 7.0E-06 TGATTGAGCAATCT 14 V_PAX_Q6_M00808 TRANSFAC - 89164614 89164624 9.0E-06 CTGGATCTCAC 11 V_TAL1_Q6_M00993 TRANSFAC - 89165678 89165687 7.0E-06 TCCAGCTGAT 10 V_BACH1_01_M00495 TRANSFAC + 89166510 89166524 6.0E-06 TGGATGAGTCAGGAT 15 V_TCF3_04_M02816 TRANSFAC - 89168160 89168176 7.0E-06 AACAGATCAAACAAACT 17 V_SPI1_03_M02078 TRANSFAC + 89166432 89166441 6.0E-06 TGAGGAAGTT 10 V_IRF2_01_M00063 TRANSFAC + 89167786 89167798 0.0E+00 GAAAACTGAAACT 13 V_P53_03_M01651 TRANSFAC + 89164537 89164556 4.0E-06 GGGCTTGCCCGGGCATGTGG 20 V_P53_03_M01651 TRANSFAC - 89164537 89164556 4.0E-06 CCACATGCCCGGGCAAGCCC 20 V_CEBPB_02_M00117 TRANSFAC - 89165793 89165806 5.0E-06 AGATTGCTCAATCA 14 V_FOXK1_04_M02856 TRANSFAC - 89164972 89164986 6.0E-06 ACAACGACAACAACT 15 V_IK1_01_M00086 TRANSFAC - 89164196 89164208 6.0E-06 GATTGGGAACATC 13 V_IRF_Q6_M00772 TRANSFAC - 89167787 89167801 0.0E+00 CTAAGTTTCAGTTTT 15 V_LXR_DR4_Q3_M00766 TRANSFAC + 89164726 89164741 3.0E-06 TGAACTGGGCTGACCC 16 V_ISRE_01_M00258 TRANSFAC - 89167785 89167799 1.0E-06 AAGTTTCAGTTTTCA 15 V_ELF5_01_M01197 TRANSFAC + 89166431 89166441 6.0E-06 ATGAGGAAGTT 11 V_PBX1_01_M00096 TRANSFAC - 89165788 89165796 4.0E-06 ATCAATCAT 9 V_DUXBL_01_M02968 TRANSFAC - 89165787 89165803 3.0E-06 TTGCTCAATCAATCATG 17 V_OCT1_04_M00138 TRANSFAC + 89166580 89166602 7.0E-06 GATTCTTTATGCAAATGCTGGCA 23 V_SP1SP3_Q4_M01219 TRANSFAC - 89164818 89164828 5.0E-06 CCGCCCCCTCT 11 V_AP4_Q5_M00175 TRANSFAC + 89168233 89168242 3.0E-06 CTCAGCTGTT 10 V_SPIB_01_M01204 TRANSFAC + 89166428 89166444 0.0E+00 AATATGAGGAAGTTGGT 17 V_TCF7_03_M02817 TRANSFAC - 89168160 89168176 5.0E-06 AACAGATCAAACAAACT 17 V_AP1_C_M00199 TRANSFAC + 89166513 89166521 3.0E-06 ATGAGTCAG 9 V_STAT4_Q5_M02117 TRANSFAC + 89165773 89165782 2.0E-06 TTACAAGAAA 10 V_STAT4_Q5_M02117 TRANSFAC - 89166646 89166655 8.0E-06 TTAAGAGAAA 10 V_ISGF3G_03_M02771 TRANSFAC + 89167786 89167800 1.0E-06 GAAAACTGAAACTTA 15 V_SMAD4_Q6_M00733 TRANSFAC - 89165452 89165466 1.0E-06 GGGGGTCAGACACCC 15 V_MYCN_01_M02259 TRANSFAC - 89164577 89164586 9.0E-06 TGCACGTGGC 10 V_AP1_01_M00517 TRANSFAC + 89166511 89166523 6.0E-06 GGATGAGTCAGGA 13 V_SP3_Q3_M00665 TRANSFAC - 89166561 89166574 6.0E-06 ACTCTAGGGCAGGG 14 V_IK3_01_M00088 TRANSFAC - 89164196 89164208 5.0E-06 GATTGGGAACATC 13 V_OCT4_02_M01124 TRANSFAC - 89165698 89165712 1.0E-06 TTTGAGATGCTAGTC 15 V_SRF_03_M01304 TRANSFAC - 89165743 89165755 7.0E-06 GTCCTTAAAAGGG 13 V_OCT1_B_M00342 TRANSFAC + 89166587 89166596 2.0E-06 TATGCAAATG 10 V_OCT_Q6_M00795 TRANSFAC - 89166587 89166597 3.0E-06 GCATTTGCATA 11 V_HNF4A_02_M02868 TRANSFAC - 89164987 89165002 5.0E-06 CTAAAAAGTCCACGGA 16 V_MAF_Q6_01_M00983 TRANSFAC - 89165395 89165405 6.0E-06 TGCAGAGTCAA 11 V_IRF7_01_M00453 TRANSFAC + 89167784 89167801 8.0E-06 CTGAAAACTGAAACTTAG 18 V_ELF1_Q6_M00746 TRANSFAC + 89166429 89166440 2.0E-06 ATATGAGGAAGT 12 V_ELF1_Q6_M00746 TRANSFAC + 89167706 89167717 7.0E-06 AATACAGGAAGA 12 V_ELF1_Q6_M00746 TRANSFAC - 89168284 89168295 9.0E-06 GCTACAGGAAAT 12 V_FXR_IR1_Q6_M00767 TRANSFAC + 89165452 89165464 4.0E-06 GGGTGTCTGACCC 13 V_ATF1_Q6_M00691 TRANSFAC - 89168145 89168155 4.0E-06 CTTTGAAGTCA 11 V_HAND1E47_01_M00222 TRANSFAC + 89165984 89165999 0.0E+00 TTTTGGGTCTGGTTTT 16 V_GABPBETA_Q3_M01876 TRANSFAC + 89164588 89164598 1.0E-05 ACCGGAAGAGA 11 V_TAL1_01_M01591 TRANSFAC + 89164355 89164367 9.0E-06 TTCCCTTCTCTTT 13 V_PKNOX2_01_M01411 TRANSFAC + 89166417 89166432 8.0E-06 ATGTGACTGTCAATAT 16 V_CEBPA_01_M00116 TRANSFAC - 89165793 89165806 1.0E-06 AGATTGCTCAATCA 14 V_OCT2_01_M01368 TRANSFAC + 89166584 89166599 1.0E-06 CTTTATGCAAATGCTG 16 V_ZBTB3_03_M02825 TRANSFAC + 89168068 89168084 6.0E-06 CACGGCACTGCACTCTA 17 V_FOXJ3_06_M02855 TRANSFAC + 89168194 89168210 5.0E-06 CTTGGCATAACAAATGA 17 V_DELTAEF1_01_M00073 TRANSFAC - 89164609 89164619 1.0E-06 TCTCACCTGAA 11 V_ERR1_Q2_M00511 TRANSFAC - 89165583 89165596 9.0E-06 TCATCAAGGACACA 14 V_NFY_01_M00287 TRANSFAC + 89164467 89164482 0.0E+00 CTCGACCAATCAGAAG 16 V_NRF2_01_M00108 TRANSFAC + 89164588 89164597 1.0E-06 ACCGGAAGAG 10 V_FOXO3_01_M00477 TRANSFAC + 89164971 89164984 1.0E-05 TAGTTGTTGTCGTT 14 V_ASCL2_04_M02841 TRANSFAC + 89166632 89166647 3.0E-06 CCATCCCCTTCCCATT 16 V_MTATA_B_M00320 TRANSFAC + 89164362 89164378 5.0E-06 CTCTTTAAAATTTCCCG 17 V_SPIC_02_M02077 TRANSFAC + 89166432 89166441 3.0E-06 TGAGGAAGTT 10 V_P53_05_M01655 TRANSFAC + 89164537 89164556 1.0E-06 GGGCTTGCCCGGGCATGTGG 20 V_P53_04_M01652 TRANSFAC + 89164537 89164556 0.0E+00 GGGCTTGCCCGGGCATGTGG 20 V_P53_04_M01652 TRANSFAC - 89164537 89164556 2.0E-06 CCACATGCCCGGGCAAGCCC 20 V_FOX_Q2_M00809 TRANSFAC + 89165595 89165607 4.0E-06 GACTGTTGGTTTT 13 V_PBX1_03_M01017 TRANSFAC - 89165787 89165798 3.0E-06 CAATCAATCATG 12 V_PBX1_03_M01017 TRANSFAC - 89168162 89168173 5.0E-06 AGATCAAACAAA 12 V_TBP_04_M02918 TRANSFAC + 89165743 89165757 7.0E-06 CCCTTTTAAGGACTC 15 V_P53_01_M00034 TRANSFAC + 89164537 89164556 0.0E+00 GGGCTTGCCCGGGCATGTGG 20 V_P53_01_M00034 TRANSFAC - 89164537 89164556 1.0E-06 CCACATGCCCGGGCAAGCCC 20 V_T3RBETA_Q6_01_M02119 TRANSFAC - 89166624 89166640 3.0E-06 AGGGGATGGGAGGTGAG 17 V_ETS1_B_M00339 TRANSFAC - 89168278 89168292 2.0E-06 ACAGGAAATGTCTGA 15 V_IRF1_Q6_01_M01881 TRANSFAC - 89167786 89167799 0.0E+00 AAGTTTCAGTTTTC 14 V_SOX2_01_M02246 TRANSFAC + 89166474 89166488 8.0E-06 CTTTTCTCCTGGAAA 15 V_SOX2_01_M02246 TRANSFAC - 89168195 89168209 2.0E-06 CATTTGTTATGCCAA 15 V_VDR_Q3_M00444 TRANSFAC - 89166625 89166639 9.0E-06 GGGGATGGGAGGTGA 15 V_VMAF_01_M00035 TRANSFAC - 89165604 89165622 4.0E-06 ACATGCTGACACGTCAAAA 19 V_IRF1_01_M00062 TRANSFAC - 89165596 89165608 8.0E-06 CAAAACCAACAGT 13 V_IRF1_01_M00062 TRANSFAC + 89167786 89167798 0.0E+00 GAAAACTGAAACT 13 V_TFE_Q6_M01029 TRANSFAC - 89168267 89168274 1.0E-05 TCATGTGA 8 V_CP2_01_M00072 TRANSFAC - 89168252 89168262 6.0E-06 GCAAAACCCAG 11 V_CEBP_Q2_01_M00912 TRANSFAC - 89165793 89165804 5.0E-06 ATTGCTCAATCA 12 V_HNF4_01_M00134 TRANSFAC - 89167186 89167204 1.0E-05 TTAGGGGCAAAGGCCTTAA 19 V_NFYA_Q5_M02106 TRANSFAC + 89164469 89164482 0.0E+00 CGACCAATCAGAAG 14 V_LTF_Q6_M01692 TRANSFAC - 89164866 89164874 1.0E-05 GTCACTTGC 9 V_PBX1_Q3_M02028 TRANSFAC - 89165788 89165796 9.0E-06 ATCAATCAT 9 V_FEV_01_M02269 TRANSFAC - 89168284 89168291 1.0E-05 CAGGAAAT 8 V_STAT1_05_M01260 TRANSFAC + 89165770 89165791 7.0E-06 ATTTTACAAGAAAGGGCCATGA 22 V_SPIB_03_M02076 TRANSFAC + 89166432 89166441 2.0E-06 TGAGGAAGTT 10 V_CEBPA_Q6_M01866 TRANSFAC + 89165793 89165805 9.0E-06 TGATTGAGCAATC 13 V_NANOG_02_M01247 TRANSFAC + 89168195 89168214 2.0E-06 TTGGCATAACAAATGAGACA 20 V_OCT4_01_M01125 TRANSFAC - 89165699 89165713 9.0E-06 TTTTGAGATGCTAGT 15

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.