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GBA2 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 57704 glucosidase, beta (bile acid) 2 chr9 - 35748725 - 35754225 35749225 Transcription Factor Binding Sites   Download all TFBS in the GBA2 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints FOXB1_forkhead_DBD_dimeric_18_1 SELEX + 35746839 35746856 0.0E+00 TCAATAAATATTTATTGA 18 FOXB1_forkhead_DBD_dimeric_18_1 SELEX - 35746839 35746856 0.0E+00 TCAATAAATATTTATTGA 18 POU4F2_POU_full_monomeric_16_1 SELEX - 35746838 35746853 6.0E-06 ATAAATATTTATTGAG 16 NF-kappaB_MA0061.1 JASPAR - 35749280 35749289 6.0E-06 GGGACTTCCC 10 NEUROD2_bHLH_full_dimeric_10_1 SELEX + 35746176 35746185 4.0E-06 GACATATGGT 10 NEUROD2_bHLH_full_dimeric_10_1 SELEX - 35746176 35746185 5.0E-06 ACCATATGTC 10 POU2F1_POU_DBD_dimeric_14_1 SELEX + 35746841 35746854 1.0E-06 AATAAATATTTATT 14 POU2F1_POU_DBD_dimeric_14_1 SELEX - 35746841 35746854 1.0E-06 AATAAATATTTATT 14 ESR2_MA0258.1 JASPAR + 35749937 35749954 9.0E-06 AGAGCTCAGGTTGTCCTG 18 FOXL1_forkhead_full_dimeric_13_1 SELEX - 35746846 35746858 4.0E-06 ATTCAATAAATAT 13 ZNF75A_C2H2_DBD_monomeric_12_1 SELEX + 35750227 35750238 0.0E+00 CCTTTTCCCACA 12 HINFP1_C2H2_full_dimeric_20_1 SELEX - 35749304 35749323 3.0E-06 GCGGCGGCGGCGGCGTCCGC 20 EWSR1-FLI1_MA0149.1 JASPAR - 35750040 35750057 4.0E-06 GGGGGAGGGGAAGGAAAG 18 FOXD2_forkhead_DBD_dimeric_14_1 SELEX + 35746841 35746854 0.0E+00 AATAAATATTTATT 14 FOXD2_forkhead_DBD_dimeric_14_1 SELEX - 35746841 35746854 0.0E+00 AATAAATATTTATT 14 Klf4_MA0039.2 JASPAR + 35746747 35746756 3.0E-06 AGGGTGTGGC 10 POU4F3_POU_DBD_monomeric_16_1 SELEX - 35746838 35746853 6.0E-06 ATAAATATTTATTGAG 16 POU4F3_POU_DBD_monomeric_16_1 SELEX + 35746842 35746857 8.0E-06 ATAAATATTTATTGAA 16 FOXD3_forkhead_DBD_dimeric_14_1 SELEX + 35746841 35746854 0.0E+00 AATAAATATTTATT 14 FOXD3_forkhead_DBD_dimeric_14_1 SELEX - 35746841 35746854 0.0E+00 AATAAATATTTATT 14 BHLHE23_bHLH_DBD_dimeric_10_1 SELEX - 35746176 35746185 4.0E-06 ACCATATGTC 10 Pou2f2_POU_DBD_dimeric_14_1 SELEX + 35746841 35746854 1.0E-05 AATAAATATTTATT 14 Pou2f2_POU_DBD_dimeric_14_1 SELEX - 35746841 35746854 1.0E-05 AATAAATATTTATT 14 SP1_MA0079.2 JASPAR + 35750048 35750057 3.0E-06 CCCCTCCCCC 10 POU2F3_POU_DBD_dimeric_12_1 SELEX + 35746842 35746853 1.0E-06 ATAAATATTTAT 12 POU2F3_POU_DBD_dimeric_12_1 SELEX - 35746842 35746853 1.0E-06 ATAAATATTTAT 12 FOXC1_forkhead_DBD_dimeric_14_1 SELEX + 35746841 35746854 0.0E+00 AATAAATATTTATT 14 FOXC1_forkhead_DBD_dimeric_14_1 SELEX - 35746841 35746854 0.0E+00 AATAAATATTTATT 14 OLIG1_bHLH_DBD_dimeric_10_1 SELEX + 35746176 35746185 7.0E-06 GACATATGGT 10 OLIG1_bHLH_DBD_dimeric_10_1 SELEX - 35746176 35746185 6.0E-06 ACCATATGTC 10 FOXC2_forkhead_DBD_dimeric_11_1 SELEX - 35750086 35750096 7.0E-06 TTAAATAAAGA 11 POU1F1_POU_DBD_monomeric_17_1 SELEX + 35746839 35746855 7.0E-06 TCAATAAATATTTATTG 17 POU1F1_POU_DBD_monomeric_17_1 SELEX - 35746840 35746856 7.0E-06 TCAATAAATATTTATTG 17 Klf12_C2H2_DBD_monomeric_15_1 SELEX - 35746743 35746757 5.0E-06 GGCCACACCCTCCCT 15 Atoh1_bHLH_DBD_dimeric_10_1 SELEX + 35746176 35746185 5.0E-06 GACATATGGT 10 Atoh1_bHLH_DBD_dimeric_10_1 SELEX - 35746176 35746185 5.0E-06 ACCATATGTC 10 FOXC2_forkhead_DBD_dimeric_14_1 SELEX + 35746841 35746854 0.0E+00 AATAAATATTTATT 14 FOXC2_forkhead_DBD_dimeric_14_1 SELEX - 35746841 35746854 0.0E+00 AATAAATATTTATT 14 FEV_MA0156.1 JASPAR - 35750119 35750126 1.0E-05 CAGGAAAT 8 POU5F1P1_POU_DBD_monomeric_12_1 SELEX + 35746842 35746853 1.0E-06 ATAAATATTTAT 12 POU5F1P1_POU_DBD_monomeric_12_1 SELEX - 35746842 35746853 1.0E-06 ATAAATATTTAT 12 SRF_MADS_full_dimeric_16_1 SELEX - 35753636 35753651 6.0E-06 TGACCAAAGATGGCCA 16 NEUROG2_bHLH_full_dimeric_10_1 SELEX - 35746176 35746185 4.0E-06 ACCATATGTC 10 FOXC1_MA0032.1 JASPAR + 35753844 35753851 7.0E-06 AGTAAGTA 8 EMX1_homeodomain_DBD_dimeric_14_1 SELEX - 35750086 35750099 6.0E-06 CCATTAAATAAAGA 14 PLAG1_MA0163.1 JASPAR + 35749366 35749379 9.0E-06 GAGGCCTAGGGGTG 14 POU3F3_POU_DBD_dimeric_12_1 SELEX + 35746842 35746853 0.0E+00 ATAAATATTTAT 12 POU3F3_POU_DBD_dimeric_12_1 SELEX - 35746842 35746853 0.0E+00 ATAAATATTTAT 12 DPRX_homeodomain_DBD_monomeric_11_1 SELEX - 35749914 35749924 7.0E-06 GAGATAATCTG 11 BHLHA15_bHLH_DBD_dimeric_10_1 SELEX - 35746176 35746185 4.0E-06 ACCATATGTC 10 OLIG2_bHLH_full_dimeric_10_1 SELEX - 35746176 35746185 4.0E-06 ACCATATGTC 10 OLIG3_bHLH_DBD_dimeric_10_1 SELEX - 35746176 35746185 4.0E-06 ACCATATGTC 10 V_HOXA9_01_M01351 TRANSFAC - 35750087 35750103 8.0E-06 GAAACCATTAAATAAAG 17 V_SPI1_01_M01203 TRANSFAC - 35750053 35750069 1.0E-06 AAAAAGGGGAACGGGGG 17 V_DBX1_01_M01483 TRANSFAC - 35746836 35746852 5.0E-06 TAAATATTTATTGAGTG 17 V_DBX1_01_M01483 TRANSFAC + 35746843 35746859 1.0E-06 TAAATATTTATTGAATG 17 V_DBX1_01_M01483 TRANSFAC - 35746843 35746859 2.0E-06 CATTCAATAAATATTTA 17 V_FREAC7_01_M00293 TRANSFAC + 35746837 35746852 6.0E-06 ACTCAATAAATATTTA 16 V_FREAC7_01_M00293 TRANSFAC - 35746843 35746858 3.0E-06 ATTCAATAAATATTTA 16 V_CDX2_Q5_01_M01659 TRANSFAC + 35746839 35746849 2.0E-06 TCAATAAATAT 11 V_CDX2_Q5_01_M01659 TRANSFAC - 35746846 35746856 2.0E-06 TCAATAAATAT 11 V_BCL6_01_M01183 TRANSFAC - 35746844 35746859 6.0E-06 CATTCAATAAATATTT 16 V_BCL6_01_M01183 TRANSFAC + 35753865 35753880 3.0E-06 TATTTAGTTTGTCTTT 16 V_DEAF1_02_M01002 TRANSFAC + 35748900 35748924 6.0E-06 TCTCCTTCGGTTGTCTCTGTAGGTC 25 V_EGR_Q6_M00807 TRANSFAC + 35748865 35748875 3.0E-06 GTGGGGGCGGC 11 V_IRF2_Q6_M01882 TRANSFAC - 35750220 35750235 5.0E-06 GGGAAAAGGAAAAGGA 16 V_YY1_Q6_M00793 TRANSFAC + 35753638 35753646 7.0E-06 GCCATCTTT 9 V_SP1_03_M02281 TRANSFAC + 35750048 35750057 3.0E-06 CCCCTCCCCC 10 V_GKLF_02_M01588 TRANSFAC - 35746745 35746756 1.0E-06 GCCACACCCTCC 12 V_CMYB_Q5_M01821 TRANSFAC + 35748248 35748258 8.0E-06 CCCAACTGCTT 11 V_HOXD13_01_M01404 TRANSFAC - 35746844 35746859 5.0E-06 CATTCAATAAATATTT 16 V_HBP1_Q2_M01661 TRANSFAC - 35746849 35746857 4.0E-06 TTCAATAAA 9 V_COMP1_01_M00057 TRANSFAC - 35746180 35746203 4.0E-06 AATATGCATTGACTGCAGACCATA 24 V_HELIOSA_02_M01004 TRANSFAC - 35750222 35750232 6.0E-06 AAAAGGAAAAG 11 V_TGIF_02_M01346 TRANSFAC - 35749979 35749995 3.0E-06 TACAATGACAGCACAGT 17 V_DBX2_01_M01360 TRANSFAC + 35750088 35750103 5.0E-06 TTTATTTAATGGTTTC 16 V_NKX61_01_M00424 TRANSFAC + 35750090 35750102 0.0E+00 TATTTAATGGTTT 13 V_MRF2_01_M00454 TRANSFAC - 35750107 35750120 2.0E-06 ATCCACAATCCCAA 14 V_HOXB9_01_M01426 TRANSFAC - 35750088 35750103 2.0E-06 GAAACCATTAAATAAA 16 V_IRF3_Q3_M01279 TRANSFAC + 35750219 35750231 6.0E-06 CTCCTTTTCCTTT 13 V_HNF3_Q6_M00791 TRANSFAC + 35746838 35746850 9.0E-06 CTCAATAAATATT 13 V_SREBP_Q6_M01168 TRANSFAC - 35750160 35750174 9.0E-06 CCTATCACACCATCT 15 V_NKX52_01_M01315 TRANSFAC + 35746831 35746847 1.0E-06 ACAAGCACTCAATAAAT 17 V_HBP1_03_M02762 TRANSFAC + 35746850 35746865 3.0E-06 TTATTGAATGAGTGGA 16 V_HMX1_02_M01481 TRANSFAC + 35746831 35746847 6.0E-06 ACAAGCACTCAATAAAT 17 V_PAX8_01_M00717 TRANSFAC + 35746848 35746862 5.0E-06 ATTTATTGAATGAGT 15 V_XFD2_01_M00268 TRANSFAC + 35746839 35746852 3.0E-06 TCAATAAATATTTA 14 V_XFD2_01_M00268 TRANSFAC - 35746843 35746856 3.0E-06 TCAATAAATATTTA 14 V_NCX_02_M01420 TRANSFAC + 35746836 35746852 1.0E-05 CACTCAATAAATATTTA 17 V_NCX_02_M01420 TRANSFAC - 35746843 35746859 5.0E-06 CATTCAATAAATATTTA 17 V_STAF_02_M00264 TRANSFAC - 35750167 35750187 7.0E-06 CTTTCCCAAGCTCCCTATCAC 21 V_TBP_06_M02814 TRANSFAC + 35746837 35746852 9.0E-06 ACTCAATAAATATTTA 16 V_TBP_06_M02814 TRANSFAC + 35746839 35746854 7.0E-06 TCAATAAATATTTATT 16 V_TBP_06_M02814 TRANSFAC - 35746841 35746856 7.0E-06 TCAATAAATATTTATT 16 V_TBP_06_M02814 TRANSFAC - 35746843 35746858 7.0E-06 ATTCAATAAATATTTA 16 V_TGIF1_01_M03111 TRANSFAC - 35749979 35749995 3.0E-06 TACAATGACAGCACAGT 17 V_STAT3_03_M01595 TRANSFAC + 35749898 35749913 8.0E-06 CCTTCTGGGAAGAAGC 16 V_ICSBP_Q6_M00699 TRANSFAC - 35750097 35750108 3.0E-06 AAAGAGAAACCA 12 V_HOXD9_Q2_M01834 TRANSFAC - 35750092 35750101 8.0E-06 AACCATTAAA 10 V_TFIII_Q6_M00706 TRANSFAC + 35746741 35746749 6.0E-06 AGAGGGAGG 9 V_IPF1_05_M01255 TRANSFAC - 35750090 35750101 3.0E-06 AACCATTAAATA 12 V_CACBINDINGPROTEIN_Q6_M00720 TRANSFAC + 35749263 35749271 8.0E-06 GAGGGTGGG 9 V_MYOGNF1_01_M00056 TRANSFAC - 35750250 35750278 0.0E+00 TGGCAGTGGATTTGGGCACTGGCCCAGGC 29 V_RBPJK_01_M01112 TRANSFAC - 35750230 35750240 3.0E-06 ACTGTGGGAAA 11 V_STAT6_02_M00500 TRANSFAC + 35750118 35750125 1.0E-05 GATTTCCT 8 V_TBP_04_M02918 TRANSFAC - 35748814 35748828 2.0E-06 CTCATTTAAGCTTTC 15 V_ZFP281_01_M01597 TRANSFAC - 35750048 35750058 7.0E-06 CGGGGGAGGGG 11 V_BBX_03_M02739 TRANSFAC - 35746846 35746860 4.0E-06 TCATTCAATAAATAT 15 V_SRF_02_M01257 TRANSFAC - 35753633 35753650 4.0E-06 GACCAAAGATGGCCAGAG 18 V_NFKAPPAB_01_M00054 TRANSFAC - 35749280 35749289 7.0E-06 GGGACTTCCC 10 V_HFH3_01_M00289 TRANSFAC - 35746839 35746851 9.0E-06 AAATATTTATTGA 13 V_HFH3_01_M00289 TRANSFAC + 35746844 35746856 9.0E-06 AAATATTTATTGA 13 V_EWSR1FLI1_01_M02252 TRANSFAC - 35750040 35750057 4.0E-06 GGGGGAGGGGAAGGAAAG 18 V_FOXJ2_01_M00422 TRANSFAC + 35746836 35746853 0.0E+00 CACTCAATAAATATTTAT 18 V_FOXJ2_01_M00422 TRANSFAC - 35746842 35746859 0.0E+00 CATTCAATAAATATTTAT 18 V_HOXD8_01_M01432 TRANSFAC - 35746836 35746852 9.0E-06 TAAATATTTATTGAGTG 17 V_HOXD8_01_M01432 TRANSFAC + 35746843 35746859 3.0E-06 TAAATATTTATTGAATG 17 V_HOXD8_01_M01432 TRANSFAC + 35750086 35750102 5.0E-06 TCTTTATTTAATGGTTT 17 V_EKLF_Q5_M01874 TRANSFAC - 35746746 35746755 5.0E-06 CCACACCCTC 10 V_SOX1_03_M02802 TRANSFAC + 35746847 35746862 3.0E-06 TATTTATTGAATGAGT 16 V_SOX1_03_M02802 TRANSFAC - 35746848 35746863 3.0E-06 CACTCATTCAATAAAT 16 V_HMX3_02_M01413 TRANSFAC + 35746831 35746847 1.0E-06 ACAAGCACTCAATAAAT 17 V_HOXD10_01_M01375 TRANSFAC - 35746843 35746859 6.0E-06 CATTCAATAAATATTTA 17 V_SREBP1_Q5_M01173 TRANSFAC - 35750160 35750174 9.0E-06 CCTATCACACCATCT 15 V_FEV_01_M02269 TRANSFAC - 35750119 35750126 1.0E-05 CAGGAAAT 8 V_DTYPEPA_B_M00334 TRANSFAC - 35750091 35750100 1.0E-06 ACCATTAAAT 10 V_STAT1_05_M01260 TRANSFAC + 35749897 35749918 1.0E-05 CCCTTCTGGGAAGAAGCCAGAT 22 V_ESR2_01_M02377 TRANSFAC + 35749937 35749954 9.0E-06 AGAGCTCAGGTTGTCCTG 18 V_SPI1_02_M02043 TRANSFAC - 35753741 35753750 8.0E-06 AGGGGAAATA 10 V_NF1_Q6_M00193 TRANSFAC - 35746194 35746211 4.0E-06 AATTGGCAAATATGCATT 18

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.