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PRF1 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 5551 perforin 1 (pore forming protein) chr10 - 72362031 - 72367531 72362531 Transcription Factor Binding Sites   Download all TFBS in the PRF1 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints NEUROD2_bHLH_full_dimeric_10_1 SELEX + 72365020 72365029 4.0E-06 GACATATGTT 10 NEUROD2_bHLH_full_dimeric_10_1 SELEX - 72365020 72365029 8.0E-06 AACATATGTC 10 SOX10_HMG_full_dimeric_14_1 SELEX + 72364095 72364108 1.0E-06 TGAATGTGCATTAA 14 ESRRA_nuclearreceptor_DBD_dimeric_19_1 SELEX + 72359016 72359034 8.0E-06 CAAGGTCACATGTAAGTGG 19 KLF16_C2H2_DBD_monomeric_11_1 SELEX + 72362540 72362550 1.0E-05 GCCCCGCCCCC 11 Tp53_p53l_DBD_dimeric_18_2 SELEX + 72365061 72365078 2.0E-06 GACTTGCTGGGACATGTG 18 Tp53_p53l_DBD_dimeric_18_2 SELEX - 72365061 72365078 1.0E-06 CACATGTCCCAGCAAGTC 18 Esrrb_MA0141.1 JASPAR + 72359012 72359023 0.0E+00 TGCTCAAGGTCA 12 SOX8_HMG_DBD_dimeric_14_1 SELEX + 72364095 72364108 1.0E-06 TGAATGTGCATTAA 14 RARG_nuclearreceptor_full_dimeric_18_1 SELEX + 72363305 72363322 2.0E-06 GAGGTCAGGGTGGGGTGA 18 BHLHE23_bHLH_DBD_dimeric_10_1 SELEX + 72365020 72365029 6.0E-06 GACATATGTT 10 BHLHE23_bHLH_DBD_dimeric_10_1 SELEX - 72365020 72365029 4.0E-06 AACATATGTC 10 BHLHE22_bHLH_DBD_dimeric_12_1 SELEX + 72365019 72365030 5.0E-06 GGACATATGTTT 12 BHLHE22_bHLH_DBD_dimeric_12_1 SELEX - 72365019 72365030 2.0E-06 AAACATATGTCC 12 SP1_MA0079.2 JASPAR + 72362541 72362550 7.0E-06 CCCCGCCCCC 10 RARA_nuclearreceptor_full_dimeric_17_1 SELEX + 72363306 72363322 5.0E-06 AGGTCAGGGTGGGGTGA 17 OLIG1_bHLH_DBD_dimeric_10_1 SELEX + 72365020 72365029 5.0E-06 GACATATGTT 10 OLIG1_bHLH_DBD_dimeric_10_1 SELEX - 72365020 72365029 3.0E-06 AACATATGTC 10 ESRRG_nuclearreceptor_full_monomeric_10_1 SELEX + 72359015 72359024 3.0E-06 TCAAGGTCAC 10 Esrra_nuclearreceptor_DBD_monomeric_11_1 SELEX + 72359014 72359024 5.0E-06 CTCAAGGTCAC 11 Atoh1_bHLH_DBD_dimeric_10_1 SELEX + 72365020 72365029 3.0E-06 GACATATGTT 10 Atoh1_bHLH_DBD_dimeric_10_1 SELEX - 72365020 72365029 1.0E-06 AACATATGTC 10 ESRRB_nuclearreceptor_DBD_monomeric_11_1 SELEX + 72359015 72359025 1.0E-06 TCAAGGTCACA 11 NEUROG2_bHLH_full_dimeric_10_1 SELEX + 72365020 72365029 2.0E-06 GACATATGTT 10 NEUROG2_bHLH_full_dimeric_10_1 SELEX - 72365020 72365029 0.0E+00 AACATATGTC 10 RORA_nuclearreceptor_DBD_dimeric_20_1 SELEX + 72363303 72363322 6.0E-06 TTGAGGTCAGGGTGGGGTGA 20 ETV6_ETS_full_dimeric_15_1 SELEX - 72362526 72362540 7.0E-06 CAGGAAGTAGAAGTG 15 Sox2_MA0143.1 JASPAR + 72365125 72365139 9.0E-06 GCATTGTTTTGCATT 15 BHLHA15_bHLH_DBD_dimeric_10_1 SELEX - 72365020 72365029 9.0E-06 AACATATGTC 10 OLIG2_bHLH_full_dimeric_10_1 SELEX + 72365020 72365029 7.0E-06 GACATATGTT 10 OLIG2_bHLH_full_dimeric_10_1 SELEX - 72365020 72365029 4.0E-06 AACATATGTC 10 TP63_p53l_DBD_dimeric_18_1 SELEX + 72365061 72365078 2.0E-06 GACTTGCTGGGACATGTG 18 TP63_p53l_DBD_dimeric_18_1 SELEX - 72365061 72365078 6.0E-06 CACATGTCCCAGCAAGTC 18 OLIG3_bHLH_DBD_dimeric_10_1 SELEX + 72365020 72365029 9.0E-06 GACATATGTT 10 OLIG3_bHLH_DBD_dimeric_10_1 SELEX - 72365020 72365029 4.0E-06 AACATATGTC 10 V_MINI20_B_M00324 TRANSFAC - 72362456 72362476 3.0E-06 TGATGCCACCATTCCAGGAGC 21 V_FOXP1_01_M00987 TRANSFAC + 72365119 72365138 9.0E-06 GTGATTGCATTGTTTTGCAT 20 RXR_RAR_DR5_MA0159.1 JASPAR + 72363306 72363322 5.0E-06 AGGTCAGGGTGGGGTGA 17 V_ERR3_Q2_01_M02094 TRANSFAC + 72359013 72359025 3.0E-06 GCTCAAGGTCACA 13 V_LRH1_Q5_01_M02098 TRANSFAC + 72359013 72359023 2.0E-06 GCTCAAGGTCA 11 V_SP1_Q6_01_M00931 TRANSFAC - 72362540 72362549 4.0E-06 GGGGCGGGGC 10 V_OCT1_Q5_01_M00930 TRANSFAC + 72365129 72365139 4.0E-06 TGTTTTGCATT 11 V_NFAT3_Q3_M01734 TRANSFAC + 72364113 72364122 6.0E-06 AGTTTTTCCT 10 V_NKX25_Q6_M02108 TRANSFAC + 72364089 72364099 8.0E-06 GACACTTGAAT 11 V_SP1_03_M02281 TRANSFAC + 72362541 72362550 7.0E-06 CCCCGCCCCC 10 V_HEN1_01_M00068 TRANSFAC + 72358950 72358971 7.0E-06 AGAGACCTCAGCTGGGCCCAGG 22 V_HEN1_01_M00068 TRANSFAC - 72358950 72358971 4.0E-06 CCTGGGCCCAGCTGAGGTCTCT 22 V_AP4_Q6_02_M01860 TRANSFAC + 72362549 72362561 0.0E+00 CCAGCTGTGGTCA 13 V_HBP1_Q2_M01661 TRANSFAC + 72358987 72358995 3.0E-06 TTCAATCAA 9 V_ETS_Q4_M00771 TRANSFAC + 72362529 72362540 6.0E-06 TTCTACTTCCTG 12 V_ETS_Q4_M00771 TRANSFAC - 72365101 72365112 6.0E-06 AAACACTTCCTC 12 V_GC_01_M00255 TRANSFAC - 72362538 72362551 9.0E-06 TGGGGGCGGGGCAG 14 V_SPI1_03_M02078 TRANSFAC + 72365100 72365109 4.0E-06 TGAGGAAGTG 10 V_ZFP410_03_M02832 TRANSFAC + 72362812 72362828 9.0E-06 ATGTGTGGGATGTAAGA 17 V_P53_03_M01651 TRANSFAC + 72365060 72365079 9.0E-06 GGACTTGCTGGGACATGTGG 20 V_AP1_Q4_M00188 TRANSFAC + 72363338 72363348 5.0E-06 AGTGACTCACA 11 V_SP1_Q6_M00196 TRANSFAC - 72362539 72362551 9.0E-06 TGGGGGCGGGGCA 13 V_SP1_Q6_M00196 TRANSFAC + 72362719 72362731 9.0E-06 GGAGGGCGGGGCG 13 V_MAZ_Q6_01_M02023 TRANSFAC - 72362575 72362588 3.0E-06 GTGGGAGGGGAGAG 14 V_TTF1_Q6_M00794 TRANSFAC - 72364089 72364100 7.0E-06 CATTCAAGTGTC 12 V_SOX18_03_M02801 TRANSFAC + 72365123 72365138 9.0E-06 TTGCATTGTTTTGCAT 16 V_HBP1_03_M02762 TRANSFAC - 72358983 72358998 9.0E-06 TATTTGATTGAATGGG 16 V_DAX1_01_M01248 TRANSFAC + 72359010 72359029 0.0E+00 ACTGCTCAAGGTCACATGTA 20 V_TEL2_Q6_M00678 TRANSFAC + 72362531 72362540 1.0E-06 CTACTTCCTG 10 V_AP1_Q2_01_M00924 TRANSFAC + 72363340 72363351 9.0E-06 TGACTCACAGGG 12 V_OCT_Q6_M00795 TRANSFAC + 72365129 72365139 7.0E-06 TGTTTTGCATT 11 V_SF1_Q6_01_M01132 TRANSFAC - 72359015 72359023 3.0E-06 TGACCTTGA 9 V_SP4_Q5_M01273 TRANSFAC + 72362540 72362550 1.0E-06 GCCCCGCCCCC 11 V_MINI19_B_M00323 TRANSFAC - 72362456 72362476 5.0E-06 TGATGCCACCATTCCAGGAGC 21 V_POU5F1_01_M01307 TRANSFAC - 72365130 72365139 9.0E-06 AATGCAAAAC 10 V_FOXL1_02_M02857 TRANSFAC - 72365124 72365139 4.0E-06 AATGCAAAACAATGCA 16 V_FOXJ3_06_M02855 TRANSFAC - 72365124 72365140 3.0E-06 AAATGCAAAACAATGCA 17 V_ERR1_Q2_M00511 TRANSFAC + 72359012 72359025 0.0E+00 TGCTCAAGGTCACA 14 V_ERR2_01_M01589 TRANSFAC + 72359015 72359026 1.0E-06 TCAAGGTCACAT 12 V_SPIC_02_M02077 TRANSFAC + 72365100 72365109 5.0E-06 TGAGGAAGTG 10 V_P53_05_M01655 TRANSFAC + 72365060 72365079 7.0E-06 GGACTTGCTGGGACATGTGG 20 V_P53_04_M01652 TRANSFAC + 72365060 72365079 6.0E-06 GGACTTGCTGGGACATGTGG 20 V_P53_04_M01652 TRANSFAC - 72365060 72365079 8.0E-06 CCACATGTCCCAGCAAGTCC 20 V_ESRRA_03_M02748 TRANSFAC + 72359012 72359028 2.0E-06 TGCTCAAGGTCACATGT 17 V_ZFP281_01_M01597 TRANSFAC - 72362541 72362551 6.0E-06 TGGGGGCGGGG 11 V_MEF3_B_M00319 TRANSFAC + 72363317 72363329 9.0E-06 GGGTGAGGTTTCC 13 V_BBX_03_M02739 TRANSFAC - 72358984 72358998 1.0E-05 TATTTGATTGAATGG 15 V_HSF_Q6_M00641 TRANSFAC - 72358934 72358946 1.0E-06 TTCTCGCAGTTTC 13 V_RXR_RAR_01_M02272 TRANSFAC + 72363306 72363322 5.0E-06 AGGTCAGGGTGGGGTGA 17 V_SOX2_01_M02246 TRANSFAC + 72365125 72365139 9.0E-06 GCATTGTTTTGCATT 15 V_VDR_Q3_M00444 TRANSFAC - 72362530 72362544 8.0E-06 GGGGCAGGAAGTAGA 15 V_EKLF_Q5_M01874 TRANSFAC - 72363310 72363319 9.0E-06 CCCCACCCTG 10 V_SOX2_Q6_M01272 TRANSFAC + 72365121 72365136 3.0E-06 GATTGCATTGTTTTGC 16 V_SP1_Q2_01_M00933 TRANSFAC + 72362541 72362550 4.0E-06 CCCCGCCCCC 10 V_SP1_Q4_01_M00932 TRANSFAC - 72362539 72362551 9.0E-06 TGGGGGCGGGGCA 13 V_SP1_Q4_01_M00932 TRANSFAC + 72362719 72362731 9.0E-06 GGAGGGCGGGGCG 13 V_PBX1_Q3_M02028 TRANSFAC + 72358987 72358995 6.0E-06 TTCAATCAA 9 V_COUP_DR1_Q6_M00765 TRANSFAC - 72362556 72362568 7.0E-06 GGACCTGTGACCA 13 V_SPIB_03_M02076 TRANSFAC + 72365100 72365109 5.0E-06 TGAGGAAGTG 10 V_NANOG_02_M01247 TRANSFAC - 72365120 72365139 1.0E-06 AATGCAAAACAATGCAATCA 20 V_T3RALPHA_Q6_M01724 TRANSFAC + 72363302 72363312 1.0E-06 CTTGAGGTCAG 11

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.