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PGPEP1 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 54858 pyroglutamyl-peptidase I chr19 + 18446407 - 18451907 18451407 Transcription Factor Binding Sites   Download all TFBS in the PGPEP1 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints NF-kappaB_MA0061.1 JASPAR + 18451116 18451125 6.0E-06 GGGACTTCCC 10 SP3_C2H2_DBD_monomeric_11_1 SELEX - 18451397 18451407 1.0E-05 GCCACGCCCCT 11 KLF16_C2H2_DBD_monomeric_11_1 SELEX - 18451307 18451317 1.0E-05 GCCCCGCCCCC 11 KLF16_C2H2_DBD_monomeric_11_1 SELEX - 18451397 18451407 7.0E-06 GCCACGCCCCT 11 Arx_homeodomain_DBD_dimeric_13_1 SELEX + 18455663 18455675 9.0E-06 AAAAATCAATTAA 13 ESR2_MA0258.1 JASPAR + 18452266 18452283 1.0E-06 GGGGGTCATTTTGACCTG 18 ESR2_MA0258.1 JASPAR - 18452267 18452284 8.0E-06 GCAGGTCAAAATGACCCC 18 KLF14_C2H2_DBD_monomeric_14_1 SELEX - 18451395 18451408 5.0E-06 GGCCACGCCCCTGT 14 CUX1_CUT_DBD_dimeric_17_1 SELEX + 18455656 18455672 3.0E-06 ATAGAAGAAAAATCAAT 17 STAT1_MA0137.2 JASPAR - 18451672 18451686 3.0E-06 ACTTTCCAGGAAGCC 15 CUX1_CUT_DBD_dimeric_18_1 SELEX + 18455667 18455684 6.0E-06 ATCAATTAAACAATCTTT 18 HMX3_homeodomain_DBD_monomeric_11_1 SELEX + 18455667 18455677 3.0E-06 ATCAATTAAAC 11 ONECUT1_CUT_full_monomeric_14_1 SELEX + 18455662 18455675 1.0E-06 GAAAAATCAATTAA 14 TCF4_bHLH_full_dimeric_10_1 SELEX - 18454767 18454776 3.0E-06 CACACCTGTA 10 ZNF740_C2H2_full_monomeric_10_1 SELEX - 18452262 18452271 5.0E-06 ACCCCCCCAC 10 PAX3_PAX_DBD_dimeric_10_1 SELEX + 18455665 18455674 2.0E-06 AAATCAATTA 10 PAX3_PAX_DBD_dimeric_10_1 SELEX - 18455665 18455674 3.0E-06 TAATTGATTT 10 RAX_homeodomain_DBD_monomeric_10_1 SELEX + 18455667 18455676 6.0E-06 ATCAATTAAA 10 ESR1_MA0112.2 JASPAR - 18452268 18452287 3.0E-06 ACAGCAGGTCAAAATGACCC 20 SP1_MA0079.2 JASPAR - 18451307 18451316 7.0E-06 CCCCGCCCCC 10 Ascl2_bHLH_DBD_dimeric_10_1 SELEX + 18451435 18451444 9.0E-06 AGCAGCTGTC 10 ONECUT2_CUT_DBD_monomeric_14_1 SELEX + 18455662 18455675 0.0E+00 GAAAAATCAATTAA 14 FOXG1_forkhead_DBD_putatively-multimeric_12_1 SELEX + 18455599 18455610 8.0E-06 GTGGACACAAAG 12 Tcf21_bHLH_DBD_dimeric_14_1 SELEX - 18451433 18451446 1.0E-05 GCGACAGCTGCTGC 14 SRY_MA0084.1 JASPAR + 18455672 18455680 1.0E-06 TTAAACAAT 9 Alx4_homeodomain_DBD_dimeric_13_1 SELEX + 18455663 18455675 7.0E-06 AAAAATCAATTAA 13 SP4_C2H2_full_monomeric_17_1 SELEX - 18451394 18451410 2.0E-06 GAGGCCACGCCCCTGTC 17 MIXL1_homeodomain_full_monomeric_10_1 SELEX + 18455667 18455676 5.0E-06 ATCAATTAAA 10 ESR1_nuclearreceptor_DBD_dimeric_17_1 SELEX + 18452267 18452283 1.0E-06 GGGGTCATTTTGACCTG 17 ESR1_nuclearreceptor_DBD_dimeric_17_1 SELEX - 18452267 18452283 0.0E+00 CAGGTCAAAATGACCCC 17 Mycn_MA0104.2 JASPAR - 18452218 18452227 8.0E-06 CCCACGTGGC 10 GSX2_homeodomain_DBD_monomeric_10_1 SELEX + 18455667 18455676 5.0E-06 ATCAATTAAA 10 CART1_homeodomain_DBD_dimeric_13_1 SELEX + 18455663 18455675 5.0E-06 AAAAATCAATTAA 13 Foxd3_MA0041.1 JASPAR - 18455670 18455681 1.0E-06 GATTGTTTAATT 12 Klf12_C2H2_DBD_monomeric_15_1 SELEX - 18451394 18451408 5.0E-06 GGCCACGCCCCTGTC 15 Stat3_MA0144.1 JASPAR + 18451675 18451684 4.0E-06 TTCCTGGAAA 10 PRDM1_C2H2_full_monomeric-or-dimeric_15_1 SELEX + 18450734 18450748 2.0E-06 AGAAAGTGACAGTTC 15 Pou5f1_MA0142.1 JASPAR - 18455644 18455658 8.0E-06 TATTTAGATGTAGAT 15 Myf_MA0055.1 JASPAR + 18451431 18451442 5.0E-06 CGGCAGCAGCTG 12 Myf_MA0055.1 JASPAR - 18451434 18451445 5.0E-06 CGACAGCTGCTG 12 HMX2_homeodomain_DBD_monomeric_11_1 SELEX + 18455667 18455677 5.0E-06 ATCAATTAAAC 11 LBX2_homeodomain_DBD_monomeric_10_1 SELEX + 18455667 18455676 1.0E-05 ATCAATTAAA 10 Zfp740_C2H2_DBD_monomeric_10_1 SELEX - 18452262 18452271 2.0E-06 ACCCCCCCAC 10 ETV6_ETS_full_monomeric_10_1 SELEX - 18452233 18452242 6.0E-06 AGCGGAAGTT 10 FOXO6_forkhead_DBD_putatively-multimeric_14_1 SELEX + 18451899 18451912 9.0E-06 TGTCCCCACACCGC 14 REST_MA0138.2 JASPAR - 18448839 18448859 7.0E-06 TCCAACACCAAGGGCAGAGTT 21 PLAG1_MA0163.1 JASPAR + 18451594 18451607 9.0E-06 GGGGCCGAGAGGGG 14 Sox2_MA0143.1 JASPAR - 18451175 18451189 5.0E-06 CCTTTATTCTGCAAG 15 MNX1_homeodomain_DBD_monomeric_10_1 SELEX + 18455667 18455676 5.0E-06 ATCAATTAAA 10 TBX1_TBX_DBD_dimeric_20_1 SELEX + 18454758 18454777 9.0E-06 TGCTGGGATTACAGGTGTGA 20 RREB1_MA0073.1 JASPAR + 18452165 18452184 6.0E-06 CTCCCCCCCACCCCCAAACC 20 PAX7_PAX_full_dimeric_10_1 SELEX + 18455665 18455674 2.0E-06 AAATCAATTA 10 PAX7_PAX_full_dimeric_10_1 SELEX - 18455665 18455674 3.0E-06 TAATTGATTT 10 ONECUT3_CUT_DBD_monomeric_14_1 SELEX + 18455662 18455675 0.0E+00 GAAAAATCAATTAA 14 HMX1_homeodomain_DBD_monomeric_11_1 SELEX + 18455667 18455677 3.0E-06 ATCAATTAAAC 11 V_FOXP1_01_M00987 TRANSFAC - 18455656 18455675 5.0E-06 TTAATTGATTTTTCTTCTAT 20 V_NFKB_C_M00208 TRANSFAC + 18451115 18451126 5.0E-06 GGGGACTTCCCT 12 V_E2A_Q6_01_M02088 TRANSFAC - 18451433 18451445 4.0E-06 CGACAGCTGCTGC 13 V_MSX3_01_M01341 TRANSFAC + 18455663 18455678 0.0E+00 AAAAATCAATTAAACA 16 V_ZSCAN4_03_M02838 TRANSFAC - 18455558 18455574 9.0E-06 GAAATGTGCACAAAGCC 17 V_ZSCAN4_03_M02838 TRANSFAC + 18455559 18455575 3.0E-06 GCTTTGTGCACATTTCA 17 V_MEQCJUN_02_M02048 TRANSFAC + 18450642 18450652 5.0E-06 AGTGAGGTCAT 11 V_ESR1_01_M02261 TRANSFAC - 18452268 18452287 3.0E-06 ACAGCAGGTCAAAATGACCC 20 V_HMGIY_Q3_M01010 TRANSFAC - 18455659 18455673 1.0E-05 AATTGATTTTTCTTC 15 V_FOXD3_01_M00130 TRANSFAC - 18455670 18455681 1.0E-06 GATTGTTTAATT 12 V_BCL6_01_M01183 TRANSFAC + 18454806 18454821 0.0E+00 CTTTTTAAAAATCTTT 16 V_BCL6_01_M01183 TRANSFAC + 18454807 18454822 1.0E-06 TTTTTAAAAATCTTTT 16 V_POU5F1_02_M02245 TRANSFAC - 18455644 18455658 8.0E-06 TATTTAGATGTAGAT 15 V_PROP1_01_M01294 TRANSFAC - 18455664 18455674 5.0E-06 TAATTGATTTT 11 V_SP1_Q6_01_M00931 TRANSFAC + 18451308 18451317 4.0E-06 GGGGCGGGGC 10 V_ISL2_01_M01328 TRANSFAC + 18455663 18455678 0.0E+00 AAAAATCAATTAAACA 16 V_ZFP740_03_M02834 TRANSFAC + 18452169 18452184 4.0E-06 CCCCCACCCCCAAACC 16 V_SOX11_04_M02899 TRANSFAC - 18455670 18455683 9.0E-06 AAGATTGTTTAATT 14 V_HOXC4_01_M01369 TRANSFAC + 18455664 18455680 8.0E-06 AAAATCAATTAAACAAT 17 V_SP1_03_M02281 TRANSFAC - 18451307 18451316 7.0E-06 CCCCGCCCCC 10 V_HFH4_01_M00742 TRANSFAC - 18455673 18455685 6.0E-06 CAAAGATTGTTTA 13 V_PITX2_Q6_M02114 TRANSFAC - 18454761 18454770 1.0E-06 TGTAATCCCA 10 V_NERF_Q2_M00531 TRANSFAC + 18451953 18451970 2.0E-06 GGGCAGGAAGTGTCCCAG 18 V_LHX3_01_M01471 TRANSFAC + 18455664 18455680 3.0E-06 AAAATCAATTAAACAAT 17 V_AREB6_04_M00415 TRANSFAC - 18455524 18455532 8.0E-06 CTGTTTCTT 9 V_SP1_02_M01303 TRANSFAC - 18452168 18452178 5.0E-06 GGGGTGGGGGG 11 V_E2A_Q2_M00804 TRANSFAC - 18452036 18452049 4.0E-06 CCACCTGCCCCTGC 14 V_E2A_Q2_M00804 TRANSFAC + 18452073 18452086 8.0E-06 CCAGCTGTCCCAGG 14 V_AP4_Q6_02_M01860 TRANSFAC - 18451431 18451443 5.0E-06 ACAGCTGCTGCCG 13 V_HOXD13_01_M01404 TRANSFAC + 18455665 18455680 4.0E-06 AAATCAATTAAACAAT 16 V_TCFAP2E_04_M02926 TRANSFAC + 18455654 18455667 6.0E-06 AAATAGAAGAAAAA 14 V_PAX6_02_M01391 TRANSFAC - 18455663 18455678 6.0E-06 TGTTTAATTGATTTTT 16 V_VSX1_01_M01335 TRANSFAC + 18455664 18455680 2.0E-06 AAAATCAATTAAACAAT 17 V_HNF6_Q6_M00639 TRANSFAC + 18455663 18455674 0.0E+00 AAAAATCAATTA 12 V_SPIC_01_M02042 TRANSFAC - 18452233 18452242 9.0E-06 AGCGGAAGTT 10 V_BACH1_01_M00495 TRANSFAC - 18454839 18454853 8.0E-06 AACCTGAGTCACGAT 15 V_SOX7_03_M02807 TRANSFAC + 18455660 18455681 6.0E-06 AAGAAAAATCAATTAAACAATC 22 V_MYF_01_M01302 TRANSFAC + 18451431 18451442 5.0E-06 CGGCAGCAGCTG 12 V_MYF_01_M01302 TRANSFAC - 18451434 18451445 5.0E-06 CGACAGCTGCTG 12 V_LMX1_01_M01409 TRANSFAC + 18455664 18455680 4.0E-06 AAAATCAATTAAACAAT 17 V_HNF3G_Q4_M02015 TRANSFAC + 18452129 18452136 7.0E-06 TGTTTGTT 8 V_HNF4_01_B_M00411 TRANSFAC + 18451933 18451947 2.0E-06 GGGGACAAAGGCCGA 15 V_ZBP89_Q4_M01816 TRANSFAC + 18450895 18450904 4.0E-06 CCCTCCCCCA 10 V_NFKB_Q6_M00194 TRANSFAC + 18451114 18451127 1.0E-05 CGGGGACTTCCCTC 14 V_HOXB9_01_M01426 TRANSFAC + 18455665 18455680 5.0E-06 AAATCAATTAAACAAT 16 V_SP1_Q6_M00196 TRANSFAC + 18451306 18451318 2.0E-06 CGGGGGCGGGGCG 13 V_MAZ_Q6_01_M02023 TRANSFAC - 18452166 18452179 2.0E-06 GGGGGTGGGGGGGA 14 V_LHX2_01_M01325 TRANSFAC + 18455664 18455680 9.0E-06 AAAATCAATTAAACAAT 17 V_LEF1_03_M02878 TRANSFAC + 18455663 18455678 6.0E-06 AAAAATCAATTAAACA 16 V_SZF11_01_M01109 TRANSFAC + 18450609 18450623 7.0E-06 CCAGGGAATGAGATG 15 V_NKX52_01_M01315 TRANSFAC + 18455664 18455680 0.0E+00 AAAATCAATTAAACAAT 17 V_ASCL2_03_M02737 TRANSFAC - 18451431 18451447 5.0E-06 CGCGACAGCTGCTGCCG 17 V_CLOX_01_M00103 TRANSFAC - 18455661 18455675 8.0E-06 TTAATTGATTTTTCT 15 V_UNCX4.1_01_M01458 TRANSFAC + 18455663 18455679 5.0E-06 AAAAATCAATTAAACAA 17 V_HMX1_02_M01481 TRANSFAC + 18455664 18455680 0.0E+00 AAAATCAATTAAACAAT 17 V_TEL2_Q6_M00678 TRANSFAC - 18451956 18451965 8.0E-06 ACACTTCCTG 10 V_ERBETA_Q5_M01875 TRANSFAC - 18452266 18452280 7.0E-06 GTCAAAATGACCCCC 15 V_ERALPHA_01_M01801 TRANSFAC + 18452268 18452282 1.0E-06 GGGTCATTTTGACCT 15 V_ERALPHA_01_M01801 TRANSFAC - 18452268 18452282 0.0E+00 AGGTCAAAATGACCC 15 V_ARID3A_04_M02735 TRANSFAC - 18455663 18455679 4.0E-06 TTGTTTAATTGATTTTT 17 V_ARID3A_04_M02735 TRANSFAC + 18455664 18455680 1.0E-05 AAAATCAATTAAACAAT 17 V_MYCN_01_M02259 TRANSFAC - 18452218 18452227 8.0E-06 CCCACGTGGC 10 V_TBP_06_M02814 TRANSFAC + 18454805 18454820 5.0E-06 CCTTTTTAAAAATCTT 16 V_STAT3_03_M01595 TRANSFAC - 18451670 18451685 7.0E-06 CTTTCCAGGAAGCCTG 16 V_STAT3_03_M01595 TRANSFAC + 18451673 18451688 9.0E-06 GCTTCCTGGAAAGTGG 16 V_LIM1_01_M01418 TRANSFAC + 18455664 18455680 0.0E+00 AAAATCAATTAAACAAT 17 V_HOXB4_01_M01424 TRANSFAC + 18455664 18455680 7.0E-06 AAAATCAATTAAACAAT 17 V_ZNF515_01_M01231 TRANSFAC + 18450630 18450639 5.0E-06 CTGGGGGGTA 10 V_SP4_Q5_M01273 TRANSFAC - 18451307 18451317 1.0E-06 GCCCCGCCCCC 11 V_HBP1_04_M02866 TRANSFAC + 18451251 18451267 0.0E+00 TGTTCCCATTTTGCAGA 17 V_S8_01_M00099 TRANSFAC + 18455663 18455678 2.0E-06 AAAAATCAATTAAACA 16 V_MTF1_06_M02882 TRANSFAC + 18455656 18455669 2.0E-06 ATAGAAGAAAAATC 14 V_FAC1_01_M00456 TRANSFAC - 18452109 18452122 0.0E+00 GCACAAAACACAAA 14 V_AREB6_02_M00413 TRANSFAC - 18454766 18454777 6.0E-06 TCACACCTGTAA 12 V_BARHL1_01_M01332 TRANSFAC + 18455663 18455678 0.0E+00 AAAAATCAATTAAACA 16 V_ZSCAN4_04_M02942 TRANSFAC - 18452111 18452126 8.0E-06 CCTGGCACAAAACACA 16 V_MEIS1_01_M00419 TRANSFAC + 18450737 18450748 9.0E-06 AAGTGACAGTTC 12 V_TCF7_04_M02921 TRANSFAC + 18454805 18454819 3.0E-06 CCTTTTTAAAAATCT 15 V_MSX1_02_M01412 TRANSFAC + 18455663 18455678 8.0E-06 AAAAATCAATTAAACA 16 V_LMX1B_01_M01363 TRANSFAC - 18455664 18455680 2.0E-06 ATTGTTTAATTGATTTT 17 V_FPM315_01_M01587 TRANSFAC + 18451687 18451698 3.0E-06 GGAGGAGGAGGA 12 V_NRSF_01_M00256 TRANSFAC - 18448839 18448859 5.0E-06 TCCAACACCAAGGGCAGAGTT 21 V_STAT1STAT1_Q3_M01212 TRANSFAC - 18451673 18451685 6.0E-06 CTTTCCAGGAAGC 13 V_PITX2_Q2_M00482 TRANSFAC - 18454760 18454770 1.0E-06 TGTAATCCCAG 11 V_REST_02_M02256 TRANSFAC - 18448839 18448859 7.0E-06 TCCAACACCAAGGGCAGAGTT 21 V_PBX1_03_M01017 TRANSFAC + 18455665 18455676 5.0E-06 AAATCAATTAAA 12 V_ZFP281_01_M01597 TRANSFAC - 18452170 18452180 1.0E-06 TGGGGGTGGGG 11 V_TBX5_Q5_M01044 TRANSFAC - 18454769 18454778 3.0E-06 CTCACACCTG 10 V_HOXC5_01_M01454 TRANSFAC + 18455664 18455680 8.0E-06 AAAATCAATTAAACAAT 17 V_SOX8_03_M02808 TRANSFAC - 18455662 18455678 1.0E-05 TGTTTAATTGATTTTTC 17 V_NFKAPPAB_01_M00054 TRANSFAC + 18451116 18451125 7.0E-06 GGGACTTCCC 10 V_MYF6_03_M02781 TRANSFAC - 18452180 18452195 3.0E-06 GAGAAACAGTTGGTTT 16 V_SOX2_01_M02246 TRANSFAC - 18451175 18451189 5.0E-06 CCTTTATTCTGCAAG 15 V_ESX1_01_M01474 TRANSFAC - 18455664 18455680 4.0E-06 ATTGTTTAATTGATTTT 17 V_ALX3_01_M01355 TRANSFAC + 18455664 18455680 9.0E-06 AAAATCAATTAAACAAT 17 V_BARHL2_01_M01446 TRANSFAC + 18455663 18455678 0.0E+00 AAAAATCAATTAAACA 16 V_SP1_Q2_01_M00933 TRANSFAC - 18451307 18451316 4.0E-06 CCCCGCCCCC 10 V_ARP1_01_M00155 TRANSFAC + 18451917 18451932 6.0E-06 CCAACCCCTGGCCCCA 16 V_LHX5_01_M01353 TRANSFAC - 18455663 18455679 8.0E-06 TTGTTTAATTGATTTTT 17 V_LHX5_01_M01353 TRANSFAC + 18455664 18455680 0.0E+00 AAAATCAATTAAACAAT 17 V_HMX3_02_M01413 TRANSFAC + 18455664 18455680 0.0E+00 AAAATCAATTAAACAAT 17 V_SOX5_07_M02909 TRANSFAC - 18455670 18455686 7.0E-06 CCAAAGATTGTTTAATT 17 V_SP1_Q4_01_M00932 TRANSFAC + 18451306 18451318 3.0E-06 CGGGGGCGGGGCG 13 V_ALX3_02_M02943 TRANSFAC + 18455664 18455680 9.0E-06 AAAATCAATTAAACAAT 17 V_BRCA_01_M01082 TRANSFAC - 18451455 18451462 1.0E-05 TTCTGTTG 8 V_STAT1_05_M01260 TRANSFAC + 18451672 18451693 2.0E-06 GGCTTCCTGGAAAGTGGAGGAG 22 V_ESR2_01_M02377 TRANSFAC + 18452266 18452283 1.0E-06 GGGGGTCATTTTGACCTG 18 V_ESR2_01_M02377 TRANSFAC - 18452267 18452284 8.0E-06 GCAGGTCAAAATGACCCC 18 V_OCT4_01_M01125 TRANSFAC - 18455644 18455658 4.0E-06 TATTTAGATGTAGAT 15 V_ER_Q6_M00191 TRANSFAC + 18452266 18452284 3.0E-06 GGGGGTCATTTTGACCTGC 19

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.