Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

SEMA5B Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 54437 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B chr3 - 122746159 - 122751659 122746659 Transcription Factor Binding Sites   Download all TFBS in the SEMA5B promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints POU2F1_POU_DBD_dimeric_14_1 SELEX - 122747589 122747602 7.0E-06 TTTACATTTTCAAA 14 SPIC_ETS_full_monomeric_14_1 SELEX + 122744969 122744982 2.0E-06 GAAAAGCGGAAGGA 14 FOXO3_MA0157.1 JASPAR - 122747451 122747458 7.0E-06 TGTAAACA 8 TBX19_TBX_DBD_dimeric_20_1 SELEX - 122749877 122749896 6.0E-06 AGTGACACTTAAATGGGAAG 20 EWSR1-FLI1_MA0149.1 JASPAR - 122749860 122749877 0.0E+00 GGAAGGAAGGAAGGAAGG 18 EWSR1-FLI1_MA0149.1 JASPAR - 122749864 122749881 0.0E+00 GGAAGGAAGGAAGGAAGG 18 EWSR1-FLI1_MA0149.1 JASPAR - 122749868 122749885 6.0E-06 AATGGGAAGGAAGGAAGG 18 EWSR1-FLI1_MA0149.1 JASPAR + 122750082 122750099 9.0E-06 GAAGATAAGGCAGGAATT 18 FOXO1_forkhead_DBD_monomeric_8_1 SELEX - 122747450 122747457 7.0E-06 GTAAACAA 8 SPIB_ETS_DBD_monomeric_14_1 SELEX + 122744969 122744982 2.0E-06 GAAAAGCGGAAGGA 14 RUNX3_RUNX_full_monomeric_10_1 SELEX + 122745581 122745590 5.0E-06 CAACCACAAA 10 Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1 SELEX - 122746633 122746648 5.0E-06 CACCGCCCCCTCCCTC 16 HOXC12_homeodomain_DBD_monomeric_9_1 SELEX + 122747598 122747606 8.0E-06 GTAAAAAAA 9 Foxq1_MA0040.1 JASPAR + 122747448 122747458 9.0E-06 AATTGTTTACA 11 FOXJ3_forkhead_DBD_dimeric_14_1 SELEX - 122742607 122742620 7.0E-06 GTACACAATTATCA 14 Pou2f2_POU_DBD_dimeric_14_1 SELEX + 122747589 122747602 6.0E-06 TTTGAAAATGTAAA 14 Pou2f2_POU_DBD_dimeric_14_1 SELEX - 122747589 122747602 8.0E-06 TTTACATTTTCAAA 14 NR4A2_nuclearreceptor_full_dimeric_16_1 SELEX + 122749879 122749894 5.0E-06 TCCCATTTAAGTGTCA 16 NR4A2_nuclearreceptor_full_dimeric_16_1 SELEX - 122749879 122749894 3.0E-06 TGACACTTAAATGGGA 16 POU2F3_POU_DBD_dimeric_12_1 SELEX + 122747590 122747601 7.0E-06 TTGAAAATGTAA 12 SRY_MA0084.1 JASPAR - 122747449 122747457 3.0E-06 GTAAACAAT 9 MGA_TBX_DBD_dimeric_18_2 SELEX + 122745833 122745850 1.0E-06 AGCGGGAGATTTCACACT 18 MGA_TBX_DBD_dimeric_18_2 SELEX - 122745833 122745850 6.0E-06 AGTGTGAAATCTCCCGCT 18 SMAD3_MAD_DBD_dimeric_10_1 SELEX + 122745050 122745059 1.0E-05 GGTCTAGACA 10 SMAD3_MAD_DBD_dimeric_10_1 SELEX - 122745050 122745059 4.0E-06 TGTCTAGACC 10 TBX2_TBX_full_dimeric_18_1 SELEX + 122745833 122745850 4.0E-06 AGCGGGAGATTTCACACT 18 POU5F1P1_POU_DBD_monomeric_12_1 SELEX + 122747590 122747601 9.0E-06 TTGAAAATGTAA 12 Pou5f1_MA0142.1 JASPAR - 122745596 122745610 8.0E-06 GTTTCTCATGGTAAT 15 SPI1_ETS_full_monomeric_14_1 SELEX + 122744969 122744982 1.0E-06 GAAAAGCGGAAGGA 14 FOXB1_forkhead_full_monomeric_9_1 SELEX - 122747450 122747458 2.0E-06 TGTAAACAA 9 FOXO3_forkhead_full_monomeric_8_1 SELEX - 122747450 122747457 7.0E-06 GTAAACAA 8 Sox2_MA0143.1 JASPAR - 122747624 122747638 6.0E-06 CCTTTGTCTTTCTCA 15 Foxj3_forkhead_DBD_dimeric_13_1 SELEX + 122747592 122747604 7.0E-06 GAAAATGTAAAAA 13 V_FOXP1_01_M00987 TRANSFAC - 122747586 122747605 2.0E-06 TTTTTTACATTTTCAAATAT 20 V_MEIS1BHOXA9_02_M00421 TRANSFAC - 122749881 122749894 1.0E-06 TGACACTTAAATGG 14 V_SPI1_01_M01203 TRANSFAC + 122744969 122744985 3.0E-06 GAAAAGCGGAAGGAGGT 17 V_TCF3_01_M01594 TRANSFAC - 122747626 122747638 5.0E-06 CCTTTGTCTTTCT 13 V_E2F4_Q6_M02090 TRANSFAC + 122747494 122747503 1.0E-05 GCGGGAGAGA 10 V_FOXO3_02_M02270 TRANSFAC - 122747451 122747458 7.0E-06 TGTAAACA 8 V_OSF2_Q6_M00731 TRANSFAC + 122745583 122745590 1.0E-05 ACCACAAA 8 V_ATF5_01_M01295 TRANSFAC - 122746666 122746676 5.0E-06 TCTCTCCCTTT 11 V_BTEB3_Q5_M01865 TRANSFAC + 122746646 122746658 9.0E-06 GTGGGGGAGGAGT 13 V_XFD1_01_M00267 TRANSFAC - 122747447 122747460 1.0E-06 CTTGTAAACAATTC 14 V_FOXA2_04_M02749 TRANSFAC - 122747446 122747462 2.0E-06 AACTTGTAAACAATTCG 17 V_EVI1_04_M00081 TRANSFAC + 122747582 122747596 8.0E-06 AAATATATTTGAAAA 15 V_BCL6_01_M01183 TRANSFAC - 122747580 122747595 0.0E+00 TTTCAAATATATTTTT 16 V_BCL6_01_M01183 TRANSFAC - 122747581 122747596 0.0E+00 TTTTCAAATATATTTT 16 V_AML3_Q6_M01856 TRANSFAC + 122745582 122745589 1.0E-05 AACCACAA 8 V_POU5F1_02_M02245 TRANSFAC - 122745596 122745610 8.0E-06 GTTTCTCATGGTAAT 15 V_SP1_Q6_01_M00931 TRANSFAC - 122745151 122745160 7.0E-06 GGGGCGGGGT 10 V_MEF2_02_M00231 TRANSFAC + 122747571 122747592 9.0E-06 TGCTGAACAAAAAATATATTTG 22 V_EOMES_03_M02747 TRANSFAC - 122745839 122745855 4.0E-06 CCCAGAGTGTGAAATCT 17 V_IRF_Q6_01_M00972 TRANSFAC + 122745562 122745572 9.0E-06 GAAAGTGAATG 11 V_NFAT3_Q3_M01734 TRANSFAC - 122745005 122745014 6.0E-06 TCTTTTTCCT 10 V_FOXO3A_Q1_M01137 TRANSFAC - 122747447 122747458 7.0E-06 TGTAAACAATTC 12 V_SOX11_04_M02899 TRANSFAC + 122747299 122747312 4.0E-06 AGAATTGTGAAGAA 14 V_AP2_Q6_01_M00915 TRANSFAC + 122745730 122745742 1.0E-05 CGCTCCGCAGGCC 13 V_SP1_02_M01303 TRANSFAC - 122745150 122745160 3.0E-06 GGGGCGGGGTG 11 V_SOX21_03_M02803 TRANSFAC + 122747579 122747594 9.0E-06 AAAAAATATATTTGAA 16 V_SOX21_03_M02803 TRANSFAC - 122747579 122747594 6.0E-06 TTCAAATATATTTTTT 16 V_TCFAP2E_04_M02926 TRANSFAC + 122747593 122747606 6.0E-06 AAAATGTAAAAAAA 14 V_CDX_Q5_M00991 TRANSFAC + 122745598 122745615 5.0E-06 TACCATGAGAAACATAAA 18 V_TAL1_GATA1_01_M02243 TRANSFAC + 122750073 122750090 3.0E-06 CTGAGAATGGAAGATAAG 18 V_ELF4_04_M02850 TRANSFAC + 122747575 122747591 4.0E-06 GAACAAAAAATATATTT 17 V_GC_01_M00255 TRANSFAC + 122746647 122746660 9.0E-06 TGGGGGAGGAGTTG 14 V_SOX7_03_M02807 TRANSFAC + 122747569 122747590 7.0E-06 TCTGCTGAACAAAAAATATATT 22 V_HELIOSA_02_M01004 TRANSFAC + 122745002 122745012 6.0E-06 TGAAGGAAAAA 11 V_ZFP105_03_M02827 TRANSFAC + 122747576 122747590 9.0E-06 AACAAAAAATATATT 15 V_FOXO1_02_M00474 TRANSFAC + 122747447 122747460 2.0E-06 GAATTGTTTACAAG 14 V_IRF2_01_M00063 TRANSFAC + 122744969 122744981 4.0E-06 GAAAAGCGGAAGG 13 V_AML2_01_M01759 TRANSFAC + 122745582 122745589 1.0E-05 AACCACAA 8 V_ZBP89_Q4_M01816 TRANSFAC - 122746647 122746656 2.0E-06 TCCTCCCCCA 10 V_SP1_Q6_M00196 TRANSFAC - 122745150 122745162 4.0E-06 GAGGGGCGGGGTG 13 V_MAZ_Q6_01_M02023 TRANSFAC + 122746629 122746642 7.0E-06 GAAGGAGGGAGGGG 14 V_OCT1_04_M00138 TRANSFAC - 122747581 122747603 9.0E-06 TTTTACATTTTCAAATATATTTT 23 V_OCT1_04_M00138 TRANSFAC + 122747582 122747604 1.0E-06 AAATATATTTGAAAATGTAAAAA 23 V_OCT1_04_M00138 TRANSFAC + 122747588 122747610 8.0E-06 ATTTGAAAATGTAAAAAAAGGTG 23 V_OCT1_04_M00138 TRANSFAC - 122747632 122747654 7.0E-06 TTTTAATTTTTCAAATCCTTTGT 23 Tal1_Gata1_MA0140.1 JASPAR + 122750073 122750090 3.0E-06 CTGAGAATGGAAGATAAG 18 V_SP1SP3_Q4_M01219 TRANSFAC - 122746636 122746646 1.0E-06 CCGCCCCCTCC 11 V_SOX12_04_M02900 TRANSFAC + 122747626 122747641 0.0E+00 AGAAAGACAAAGGATT 16 V_SOX12_04_M02900 TRANSFAC + 122750033 122750048 5.0E-06 AACAGGACAAAGAAGT 16 V_SPIB_01_M01204 TRANSFAC + 122744969 122744985 5.0E-06 GAAAAGCGGAAGGAGGT 17 V_KLF7_03_M02773 TRANSFAC + 122745148 122745163 5.0E-06 CTCACCCCGCCCCTCT 16 V_SP1_01_M00008 TRANSFAC - 122745151 122745160 3.0E-06 GGGGCGGGGT 10 V_TBP_06_M02814 TRANSFAC - 122747579 122747594 2.0E-06 TTCAAATATATTTTTT 16 V_OCT4_02_M01124 TRANSFAC - 122745595 122745609 2.0E-06 TTTCTCATGGTAATT 15 V_SOX11_03_M02795 TRANSFAC + 122747571 122747587 3.0E-06 TGCTGAACAAAAAATAT 17 V_SOX11_03_M02795 TRANSFAC + 122747626 122747642 1.0E-06 AGAAAGACAAAGGATTT 17 V_BLIMP1_Q6_M01066 TRANSFAC + 122745560 122745575 2.0E-06 CGGAAAGTGAATGGGC 16 V_IRX5_01_M01472 TRANSFAC + 122747451 122747467 9.0E-06 TGTTTACAAGTTTAAGT 17 V_SOX15_03_M02799 TRANSFAC + 122747571 122747587 2.0E-06 TGCTGAACAAAAAATAT 17 V_CIZ_01_M00734 TRANSFAC + 122747578 122747586 6.0E-06 CAAAAAATA 9 V_MTF1_06_M02882 TRANSFAC + 122747594 122747607 1.0E-05 AAATGTAAAAAAAG 14 V_FAC1_01_M00456 TRANSFAC + 122747575 122747588 4.0E-06 GAACAAAAAATATA 14 V_TAL1_01_M01591 TRANSFAC - 122746670 122746682 1.0E-06 CCTCCTTCTCTCC 13 V_TAL1_01_M01591 TRANSFAC - 122750082 122750094 2.0E-06 CTGCCTTATCTTC 13 V_TAL1_01_M01591 TRANSFAC - 122750106 122750118 4.0E-06 CCTGCTTCTCTGT 13 V_FOXL1_04_M02753 TRANSFAC - 122747446 122747462 3.0E-06 AACTTGTAAACAATTCG 17 V_FOXL1_04_M02753 TRANSFAC + 122747593 122747609 9.0E-06 AAAATGTAAAAAAAGGT 17 V_MYOGNF1_01_M00056 TRANSFAC + 122750042 122750070 5.0E-06 AAGAAGTCTTCATTGGAAATGGCCATTCT 29 V_NCX_01_M00484 TRANSFAC - 122745593 122745602 2.0E-06 TGGTAATTTG 10 V_FPM315_01_M01587 TRANSFAC + 122746604 122746615 1.0E-06 CAGGGAGGAGGA 12 V_MYB_Q3_M00773 TRANSFAC + 122750011 122750021 2.0E-06 AGAGCCAGTTA 11 V_ASCL2_04_M02841 TRANSFAC - 122745008 122745023 3.0E-06 CTAACCCCATCTTTTT 16 V_TBP_04_M02918 TRANSFAC + 122749880 122749894 5.0E-06 CCCATTTAAGTGTCA 15 V_SMAD_Q6_01_M00974 TRANSFAC + 122750099 122750109 2.0E-06 TTGCCAGACAG 11 V_ZFP281_01_M01597 TRANSFAC + 122746647 122746657 9.0E-06 TGGGGGAGGAG 11 V_OCT1_07_M00248 TRANSFAC - 122745595 122745606 6.0E-06 CTCATGGTAATT 12 V_SOX8_03_M02808 TRANSFAC - 122747571 122747587 1.0E-05 ATATTTTTTGTTCAGCA 17 V_SOX2_01_M02246 TRANSFAC - 122747624 122747638 6.0E-06 CCTTTGTCTTTCTCA 15 V_SRF_06_M02916 TRANSFAC + 122747573 122747589 9.0E-06 CTGAACAAAAAATATAT 17 V_EWSR1FLI1_01_M02252 TRANSFAC - 122749860 122749877 0.0E+00 GGAAGGAAGGAAGGAAGG 18 V_EWSR1FLI1_01_M02252 TRANSFAC - 122749864 122749881 0.0E+00 GGAAGGAAGGAAGGAAGG 18 V_EWSR1FLI1_01_M02252 TRANSFAC - 122749868 122749885 6.0E-06 AATGGGAAGGAAGGAAGG 18 V_EWSR1FLI1_01_M02252 TRANSFAC + 122750082 122750099 9.0E-06 GAAGATAAGGCAGGAATT 18 V_SOX2_Q6_M01272 TRANSFAC - 122747627 122747642 1.0E-06 AAATCCTTTGTCTTTC 16 V_PAX4_02_M00377 TRANSFAC + 122745591 122745601 4.0E-06 GACAAATTACC 11 V_PIT1_Q6_M00802 TRANSFAC - 122747579 122747596 6.0E-06 TTTTCAAATATATTTTTT 18 V_SP1_Q2_01_M00933 TRANSFAC + 122745152 122745161 7.0E-06 CCCCGCCCCT 10 V_FOXO4_01_M00472 TRANSFAC - 122747447 122747457 4.0E-06 GTAAACAATTC 11 V_IRXB3_01_M01377 TRANSFAC - 122747588 122747604 8.0E-06 TTTTTACATTTTCAAAT 17 V_FOXK1_03_M02752 TRANSFAC - 122747446 122747462 2.0E-06 AACTTGTAAACAATTCG 17 V_SMAD1_01_M01590 TRANSFAC + 122747628 122747639 0.0E+00 AAAGACAAAGGA 12 V_SOX14_03_M02798 TRANSFAC - 122747579 122747594 1.0E-05 TTCAAATATATTTTTT 16 V_NANOG_02_M01247 TRANSFAC + 122747569 122747588 6.0E-06 TCTGCTGAACAAAAAATATA 20 V_NANOG_02_M01247 TRANSFAC + 122747624 122747643 2.0E-06 TGAGAAAGACAAAGGATTTG 20

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.