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POMC Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 5443 proopiomelanocortin chr2 - 25391059 - 25396559 25391559 Transcription Factor Binding Sites   Download all TFBS in the POMC promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints POU4F2_POU_full_monomeric_16_1 SELEX - 25391682 25391697 7.0E-06 ATCCATAATTAAGTTC 16 CTCF_MA0139.1 JASPAR + 25389089 25389107 2.0E-06 CAGCCATTAGATGGCACTG 19 FOXJ2_forkhead_DBD_dimeric_13_1 SELEX + 25387739 25387751 9.0E-06 GCCAACATTAACA 13 ESRRA_nuclearreceptor_DBD_dimeric_19_1 SELEX + 25387771 25387789 7.0E-06 TAAAGGCATTTTAAGGACA 19 ALX3_homeodomain_full_monomeric_10_1 SELEX - 25388786 25388795 3.0E-06 TCTAATTACA 10 SPIC_ETS_full_monomeric_14_1 SELEX + 25396252 25396265 7.0E-06 TGAATCCGGAAGTC 14 BARX1_homeodomain_DBD_dimeric_17_1 SELEX - 25387771 25387787 2.0E-06 TCCTTAAAATGCCTTTA 17 POU3F3_POU_DBD_monomeric_12_1 SELEX - 25391686 25391697 8.0E-06 ATCCATAATTAA 12 Dlx1_homeodomain_DBD_monomeric_8_1 SELEX - 25391686 25391693 4.0E-06 ATAATTAA 8 ELF4_ETS_full_monomeric_12_1 SELEX + 25396254 25396265 4.0E-06 AATCCGGAAGTC 12 NR2F6_nuclearreceptor_full_dimeric_14_1 SELEX + 25396260 25396273 9.0E-06 GAAGTCAGAGGTTA 14 TBP_MA0108.2 JASPAR - 25391467 25391481 8.0E-06 GTATATAAGGACAGA 15 Alx1_homeodomain_DBD_monomeric_10_1 SELEX - 25388786 25388795 3.0E-06 TCTAATTACA 10 STAT1_MA0137.2 JASPAR + 25389503 25389517 6.0E-06 GCCTTCCTGGAAAGC 15 STAT1_MA0137.2 JASPAR - 25389503 25389517 7.0E-06 GCTTTCCAGGAAGGC 15 ISX_homeodomain_DBD_dimeric_13_1 SELEX + 25388782 25388794 6.0E-06 GAAATGTAATTAG 13 ISX_homeodomain_DBD_dimeric_13_1 SELEX - 25388787 25388799 3.0E-06 CTCATCTAATTAC 13 PROP1_homeodomain_full_dimeric_11_1 SELEX + 25388783 25388793 4.0E-06 AAATGTAATTA 11 ESRRG_nuclearreceptor_full_dimeric_18_1 SELEX - 25387730 25387747 6.0E-06 AATGTTGGCTCAAGGTCC 18 ESRRG_nuclearreceptor_full_dimeric_18_1 SELEX + 25387772 25387789 2.0E-06 AAAGGCATTTTAAGGACA 18 FOXD3_forkhead_DBD_dimeric_14_1 SELEX - 25387738 25387751 4.0E-06 TGTTAATGTTGGCT 14 ELF3_ETS_full_monomeric_13_1 SELEX + 25396254 25396266 1.0E-05 AATCCGGAAGTCA 13 NR2F1_nuclearreceptor_DBD_dimeric_15_1 SELEX + 25396260 25396274 9.0E-06 GAAGTCAGAGGTTAC 15 DRGX_homeodomain_DBD_dimeric_13_1 SELEX + 25388782 25388794 9.0E-06 GAAATGTAATTAG 13 PHOX2B_homeodomain_full_dimeric_11_1 SELEX + 25388783 25388793 2.0E-06 AAATGTAATTA 11 DLX6_homeodomain_DBD_monomeric_8_1 SELEX - 25391686 25391693 9.0E-06 ATAATTAA 8 NFATC1_NFAT_full_dimeric_20_1 SELEX - 25389194 25389213 1.0E-05 AATGGGAACAGCCTGTCCCT 20 VAX1_homeodomain_DBD_monomeric_8_1 SELEX + 25391686 25391693 9.0E-06 TTAATTAT 8 CTCF_C2H2_full_monomeric_17_1 SELEX - 25389090 25389106 7.0E-06 AGTGCCATCTAATGGCT 17 NR3C2_nuclearreceptor_DBD_dimeric_17_1 SELEX + 25389194 25389210 4.0E-06 AGGGACAGGCTGTTCCC 17 NR3C2_nuclearreceptor_DBD_dimeric_17_1 SELEX - 25389194 25389210 5.0E-06 GGGAACAGCCTGTCCCT 17 DLX3_homeodomain_DBD_monomeric_8_1 SELEX - 25391686 25391693 9.0E-06 ATAATTAA 8 POU1F1_POU_DBD_monomeric_17_1 SELEX - 25391684 25391700 8.0E-06 GCCATCCATAATTAAGT 17 PRRX1_homeodomain_full_dimeric_11_1 SELEX + 25388783 25388793 3.0E-06 AAATGTAATTA 11 PRRX1_homeodomain_full_dimeric_11_1 SELEX - 25388788 25388798 4.0E-06 TCATCTAATTA 11 CART1_homeodomain_DBD_dimeric_13_1 SELEX + 25388782 25388794 4.0E-06 GAAATGTAATTAG 13 Uncx_homeodomain_DBD_dimeric_13_1 SELEX + 25388782 25388794 4.0E-06 GAAATGTAATTAG 13 Stat3_MA0144.1 JASPAR - 25387642 25387651 1.0E-05 TGCCTGGAAG 10 Stat3_MA0144.1 JASPAR - 25389505 25389514 1.0E-06 TTCCAGGAAG 10 Stat3_MA0144.1 JASPAR + 25389506 25389515 4.0E-06 TTCCTGGAAA 10 PRDM1_C2H2_full_monomeric-or-dimeric_15_1 SELEX + 25388941 25388955 1.0E-06 TGGAAGTGAAAGTCC 15 POU3F1_POU_DBD_monomeric_12_2 SELEX - 25391686 25391697 6.0E-06 ATCCATAATTAA 12 EHF_ETS_full_monomeric_12_1 SELEX + 25396254 25396265 7.0E-06 AATCCGGAAGTC 12 ELF1_ETS_full_monomeric_12_1 SELEX + 25396254 25396265 2.0E-06 AATCCGGAAGTC 12 NR3C1_MA0113.1 JASPAR - 25389193 25389210 2.0E-06 GGGAACAGCCTGTCCCTT 18 PHOX2A_homeodomain_DBD_dimeric_11_1 SELEX + 25388783 25388793 2.0E-06 AAATGTAATTA 11 NR3C1_nuclearreceptor_DBD_dimeric_17_1 SELEX + 25389194 25389210 4.0E-06 AGGGACAGGCTGTTCCC 17 NR3C1_nuclearreceptor_DBD_dimeric_17_1 SELEX - 25389194 25389210 5.0E-06 GGGAACAGCCTGTCCCT 17 POU4F1_POU_DBD_monomeric_14_1 SELEX - 25391684 25391697 5.0E-06 ATCCATAATTAAGT 14 AR_nuclearreceptor_full_dimeric_17_1 SELEX + 25389194 25389210 2.0E-06 AGGGACAGGCTGTTCCC 17 AR_nuclearreceptor_full_dimeric_17_1 SELEX - 25389194 25389210 4.0E-06 GGGAACAGCCTGTCCCT 17 DLX5_homeodomain_FL_monomeric_8_1 SELEX - 25391686 25391693 8.0E-06 ATAATTAA 8 V_AREB6_01_M00412 TRANSFAC + 25391360 25391372 3.0E-06 CCCTTACCTGTCT 13 V_NFKB_Q6_01_M00774 TRANSFAC + 25389506 25389521 6.0E-06 TTCCTGGAAAGCCCCA 16 V_CDX2_Q5_01_M01659 TRANSFAC - 25391686 25391696 1.0E-05 TCCATAATTAA 11 V_FLI1_Q6_M01208 TRANSFAC + 25396257 25396267 4.0E-06 CCGGAAGTCAG 11 V_AREB6_03_M00414 TRANSFAC - 25389122 25389133 1.0E-05 GCGCACCTGGGC 12 V_NRSF_Q4_M01028 TRANSFAC - 25391524 25391542 1.0E-06 GAGCTGCTCCTTGTGCTGC 19 V_ACAAT_B_M00309 TRANSFAC + 25387678 25387686 8.0E-06 GATTGGTGG 9 V_FOXO4_02_M00476 TRANSFAC - 25387742 25387755 6.0E-06 GTGTTGTTAATGTT 14 V_PROP1_01_M01294 TRANSFAC - 25388783 25388793 2.0E-06 TAATTACATTT 11 V_IRF_Q6_01_M00972 TRANSFAC + 25388942 25388952 4.0E-06 GGAAGTGAAAG 11 V_IRF2_Q6_M01882 TRANSFAC + 25388940 25388955 2.0E-06 TTGGAAGTGAAAGTCC 16 V_HOXA4_01_M01370 TRANSFAC - 25391682 25391698 7.0E-06 CATCCATAATTAAGTTC 17 V_MAF_Q6_M00648 TRANSFAC - 25388982 25388997 1.0E-06 GAGAAGGAAGTGGCCT 16 V_HOXA2_01_M01402 TRANSFAC + 25388784 25388799 3.0E-06 AATGTAATTAGATGAG 16 V_DLX2_01_M01468 TRANSFAC + 25388784 25388799 1.0E-06 AATGTAATTAGATGAG 16 V_OCTAMER_02_M01477 TRANSFAC + 25391681 25391697 9.0E-06 AGAACTTAATTATGGAT 17 V_AFP1_Q6_M00616 TRANSFAC + 25387745 25387755 1.0E-06 ATTAACAACAC 11 V_LHX3A_01_M00510 TRANSFAC + 25391684 25391693 8.0E-06 ACTTAATTAT 10 V_K2B_01_M01348 TRANSFAC - 25391681 25391697 8.0E-06 ATCCATAATTAAGTTCT 17 V_BRN2_01_M00145 TRANSFAC - 25391685 25391700 7.0E-06 GCCATCCATAATTAAG 16 V_NR3C1_01_M02219 TRANSFAC - 25389193 25389210 2.0E-06 GGGAACAGCCTGTCCCTT 18 V_REX1_01_M01695 TRANSFAC + 25389088 25389097 1.0E-06 GCAGCCATTA 10 V_HOXA6_01_M01392 TRANSFAC + 25388784 25388799 9.0E-06 AATGTAATTAGATGAG 16 V_CART1_01_M00416 TRANSFAC + 25388802 25388819 1.0E-06 AAGTAATTCACATTAAAG 18 V_CART1_01_M00416 TRANSFAC - 25388802 25388819 6.0E-06 CTTTAATGTGAATTACTT 18 V_TATA_01_M00252 TRANSFAC - 25391467 25391481 8.0E-06 GTATATAAGGACAGA 15 V_HOXA1_01_M01487 TRANSFAC - 25388784 25388799 2.0E-06 CTCATCTAATTACATT 16 V_HNF3A_01_M01261 TRANSFAC + 25387668 25387677 7.0E-06 AAGCAAACAA 10 V_GSH2_01_M01326 TRANSFAC + 25388784 25388799 3.0E-06 AATGTAATTAGATGAG 16 V_OCT1_08_M01354 TRANSFAC - 25391683 25391698 7.0E-06 CATCCATAATTAAGTT 16 V_AR_04_M01201 TRANSFAC + 25389195 25389209 6.0E-06 GGGACAGGCTGTTCC 15 V_ERALPHA_01_M01801 TRANSFAC + 25396268 25396282 1.0E-06 AGGTTACAGTGAGCC 15 V_ERALPHA_01_M01801 TRANSFAC - 25396268 25396282 4.0E-06 GGCTCACTGTAACCT 15 V_PNR_01_M01650 TRANSFAC + 25396260 25396273 3.0E-06 GAAGTCAGAGGTTA 14 V_PMX2B_01_M01356 TRANSFAC + 25391681 25391697 9.0E-06 AGAACTTAATTATGGAT 17 V_CTCF_02_M01259 TRANSFAC + 25389086 25389105 8.0E-06 GAGCAGCCATTAGATGGCAC 20 V_CTCF_01_M01200 TRANSFAC + 25389088 25389107 5.0E-06 GCAGCCATTAGATGGCACTG 20 V_BLIMP1_Q6_M01066 TRANSFAC + 25388940 25388955 3.0E-06 TTGGAAGTGAAAGTCC 16 V_EHF_06_M02745 TRANSFAC + 25396252 25396266 6.0E-06 TGAATCCGGAAGTCA 15 V_TAL1_01_M01591 TRANSFAC + 25388988 25389000 0.0E+00 CTTCCTTCTCTCT 13 V_CACBINDINGPROTEIN_Q6_M00720 TRANSFAC - 25389003 25389011 8.0E-06 GAGGGTGGG 9 V_LUN1_01_M00480 TRANSFAC + 25396215 25396231 7.0E-06 TCCTAGCTACTCAGGAA 17 V_FOXJ3_06_M02855 TRANSFAC + 25387697 25387713 1.0E-06 AGGAGCAAAACAATGTT 17 V_ZSCAN4_04_M02942 TRANSFAC + 25387666 25387681 9.0E-06 AGAAGCAAACAAGATT 16 V_HDX_01_M01333 TRANSFAC - 25388961 25388977 1.0E-06 AAGTAGAAATCAGCGCT 17 V_STAT1STAT1_Q3_M01212 TRANSFAC - 25389504 25389516 6.0E-06 CTTTCCAGGAAGG 13 V_HOXB3_01_M01330 TRANSFAC + 25388783 25388799 9.0E-06 AAATGTAATTAGATGAG 17 V_SOX2_Q6_M01272 TRANSFAC - 25387701 25387716 4.0E-06 GCCAACATTGTTTTGC 16 V_HNF3B_Q6_M02014 TRANSFAC - 25387669 25387677 6.0E-06 TTGTTTGCT 9 V_MOX1_01_M01443 TRANSFAC + 25388784 25388799 0.0E+00 AATGTAATTAGATGAG 16 V_BSX_01_M01442 TRANSFAC + 25388784 25388799 1.0E-06 AATGTAATTAGATGAG 16 V_SOX15_04_M02903 TRANSFAC + 25388781 25388795 2.0E-06 AGAAATGTAATTAGA 15 V_HOXD3_01_M01338 TRANSFAC - 25388784 25388799 3.0E-06 CTCATCTAATTACATT 16 V_LHX4_01_M01421 TRANSFAC - 25388782 25388798 3.0E-06 TCATCTAATTACATTTC 17 V_LHX4_01_M01421 TRANSFAC + 25391682 25391698 6.0E-06 GAACTTAATTATGGATG 17 V_SOX5_04_M02910 TRANSFAC - 25391683 25391697 1.0E-06 ATCCATAATTAAGTT 15 V_STAT1_05_M01260 TRANSFAC - 25389496 25389517 8.0E-06 GCTTTCCAGGAAGGCCTGAAGT 22 V_STAT1_05_M01260 TRANSFAC + 25389503 25389524 8.0E-06 GCCTTCCTGGAAAGCCCCAGAG 22 V_AR_01_M00481 TRANSFAC + 25389195 25389209 4.0E-06 GGGACAGGCTGTTCC 15 V_SOX14_03_M02798 TRANSFAC + 25388780 25388795 9.0E-06 AAGAAATGTAATTAGA 16 V_HOX13_02_M01452 TRANSFAC + 25388784 25388799 1.0E-06 AATGTAATTAGATGAG 16 V_TR4_03_M01782 TRANSFAC + 25396261 25396273 5.0E-06 AAGTCAGAGGTTA 13 V_NANOG_02_M01247 TRANSFAC + 25388790 25388809 5.0E-06 ATTAGATGAGAAAAGTAATT 20 V_ER_Q6_M00191 TRANSFAC + 25396266 25396284 5.0E-06 AGAGGTTACAGTGAGCCAA 19 V_IPF1_06_M01438 TRANSFAC + 25388784 25388799 3.0E-06 AATGTAATTAGATGAG 16

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.