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PION Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 54103 gamma-secretase activating protein chr7 - 77045217 - 77050717 77045717 Transcription Factor Binding Sites   Download all TFBS in the PION promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints POU4F2_POU_full_monomeric_16_1 SELEX + 77043428 77043443 8.0E-06 ATACATATCTCATGAG 16 FOXJ2_forkhead_DBD_dimeric_13_1 SELEX - 77043475 77043487 4.0E-06 ATCAACAAATACA 13 GABPA_MA0062.2 JASPAR - 77045537 77045547 6.0E-06 CCGGAAGCGGC 11 En1_MA0027.1 JASPAR - 77043441 77043451 8.0E-06 AAGTAATTCTC 11 FOXC2_forkhead_DBD_monomeric_12_1 SELEX - 77043479 77043490 7.0E-06 TACATCAACAAA 12 LHX2_homeodomain_DBD_dimeric_15_1 SELEX + 77046186 77046200 1.0E-06 TTATTAAGGTAATGA 15 LHX2_homeodomain_DBD_dimeric_15_1 SELEX - 77046186 77046200 2.0E-06 TCATTACCTTAATAA 15 RXRG_nuclearreceptor_full_dimeric_14_1 SELEX + 77044795 77044808 7.0E-06 AGGCTCAAAAGTCA 14 SOX8_HMG_full_dimeric_15_1 SELEX - 77043464 77043478 9.0E-06 TACAATTGAAGTTTT 15 Mafb_bZIP_DBD_monomeric_12_1 SELEX + 77043359 77043370 5.0E-06 AAAATGCTTACA 12 Sox17_HMG_DBD_dimeric_15_1 SELEX - 77043464 77043478 9.0E-06 TACAATTGAAGTTTT 15 RARG_nuclearreceptor_full_dimeric_18_1 SELEX - 77043343 77043360 4.0E-06 TTGGTCAATAAGGGGTCA 18 Foxc1_forkhead_DBD_dimeric_11_1 SELEX - 77043477 77043487 6.0E-06 ATCAACAAATA 11 Rarb_nuclearreceptor_DBD_dimeric_17_1 SELEX - 77043343 77043359 7.0E-06 TGGTCAATAAGGGGTCA 17 SP1_MA0079.2 JASPAR + 77045492 77045501 7.0E-06 CCCCGCCCCC 10 SP1_MA0079.2 JASPAR + 77045748 77045757 7.0E-06 CCCCGCCCCC 10 ZIC3_C2H2_full_monomeric_15_1 SELEX + 77045751 77045765 1.0E-05 CGCCCCCTGCTGCTT 15 RARA_nuclearreceptor_full_dimeric_17_1 SELEX - 77043343 77043359 1.0E-06 TGGTCAATAAGGGGTCA 17 SPDEF_ETS_full_putative-multimer_15_1 SELEX + 77045086 77045100 1.0E-05 GTGGTCACGGATTCT 15 NR3C2_nuclearreceptor_DBD_dimeric_17_1 SELEX + 77045043 77045059 1.0E-06 GGGGACAAACTGTTCCA 17 NR3C2_nuclearreceptor_DBD_dimeric_17_1 SELEX - 77045043 77045059 1.0E-06 TGGAACAGTTTGTCCCC 17 FOXC2_forkhead_DBD_dimeric_11_1 SELEX - 77043477 77043487 8.0E-06 ATCAACAAATA 11 NRL_bZIP_DBD_monomeric_11_1 SELEX + 77043359 77043369 8.0E-06 AAAATGCTTAC 11 POU1F1_POU_DBD_monomeric_17_1 SELEX + 77043425 77043441 8.0E-06 ATCATACATATCTCATG 17 RFX5_RFX_DBD_dimeric_16_3 SELEX - 77046184 77046199 1.0E-05 CATTACCTTAATAACA 16 MEOX2_homeodomain_DBD_dimeric_17_1 SELEX + 77046185 77046201 2.0E-06 GTTATTAAGGTAATGAG 17 MEOX2_homeodomain_DBD_dimeric_17_1 SELEX - 77046185 77046201 4.0E-06 CTCATTACCTTAATAAC 17 NR3C1_MA0113.1 JASPAR + 77045043 77045060 9.0E-06 GGGGACAAACTGTTCCAC 18 RORA_nuclearreceptor_DBD_dimeric_20_1 SELEX - 77043343 77043362 9.0E-06 TTTTGGTCAATAAGGGGTCA 20 RARG_nuclearreceptor_full_dimeric_16_1 SELEX - 77045201 77045216 9.0E-06 GAGGGCAGAGGGTCGT 16 FOXC1_forkhead_DBD_dimeric_13_1 SELEX - 77043477 77043489 4.0E-06 ACATCAACAAATA 13 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 77043475 77043487 4.0E-06 ATCAACAAATACA 13 Foxj3_forkhead_DBD_dimeric_13_1 SELEX + 77045016 77045028 7.0E-06 AGACACATAAACA 13 NR3C1_nuclearreceptor_DBD_dimeric_17_1 SELEX + 77045043 77045059 2.0E-06 GGGGACAAACTGTTCCA 17 NR3C1_nuclearreceptor_DBD_dimeric_17_1 SELEX - 77045043 77045059 2.0E-06 TGGAACAGTTTGTCCCC 17 AR_nuclearreceptor_full_dimeric_17_1 SELEX + 77045043 77045059 4.0E-06 GGGGACAAACTGTTCCA 17 AR_nuclearreceptor_full_dimeric_17_1 SELEX - 77045043 77045059 8.0E-06 TGGAACAGTTTGTCCCC 17 SOX9_HMG_full_dimeric_17_1 SELEX - 77043463 77043479 8.0E-06 ATACAATTGAAGTTTTC 17 V_KLF15_Q2_M01714 TRANSFAC - 77045487 77045500 8.0E-06 GGGGCGGGGAGTGG 14 V_FREAC7_01_M00293 TRANSFAC - 77043477 77043492 3.0E-06 TTTACATCAACAAATA 16 V_FREAC7_01_M00293 TRANSFAC + 77045017 77045032 8.0E-06 GACACATAAACACGTC 16 V_AREB6_03_M00414 TRANSFAC - 77044889 77044900 2.0E-06 CCGCACCTGTGC 12 V_AREB6_03_M00414 TRANSFAC + 77046540 77046551 3.0E-06 CTACACCTGGAC 12 V_XFD1_01_M00267 TRANSFAC + 77045019 77045032 9.0E-06 CACATAAACACGTC 14 V_HMGIY_Q3_M01010 TRANSFAC + 77043472 77043486 6.0E-06 AATTGTATTTGTTGA 15 V_SP1_Q6_01_M00931 TRANSFAC + 77045869 77045878 7.0E-06 GGGGCGGGGT 10 V_EGR_Q6_M00807 TRANSFAC - 77045493 77045503 6.0E-06 GTGGGGGCGGG 11 V_GLI1_Q2_M01042 TRANSFAC - 77045082 77045091 6.0E-06 GACCACCAAG 10 V_P50P50_Q3_M01223 TRANSFAC + 77045478 77045490 6.0E-06 GAGGGACTCCCAC 13 V_IRF3_05_M02767 TRANSFAC - 77045761 77045774 8.0E-06 CAGAACCGAAAGCA 14 V_SP1_03_M02281 TRANSFAC + 77045492 77045501 7.0E-06 CCCCGCCCCC 10 V_SP1_03_M02281 TRANSFAC + 77045748 77045757 7.0E-06 CCCCGCCCCC 10 V_SP1_02_M01303 TRANSFAC - 77045490 77045500 3.0E-06 GGGGCGGGGAG 11 V_SP1_02_M01303 TRANSFAC + 77045869 77045879 3.0E-06 GGGGCGGGGTG 11 V_HNF4A_04_M02764 TRANSFAC - 77043338 77043354 7.0E-06 AATAAGGGGTCAAGGAG 17 V_NFAT2_01_M01748 TRANSFAC - 77043378 77043386 5.0E-06 ATGGAAATT 9 V_NR3C1_01_M02219 TRANSFAC + 77045043 77045060 9.0E-06 GGGGACAAACTGTTCCAC 18 V_HNF1_C_M00206 TRANSFAC + 77046192 77046208 4.0E-06 AGGTAATGAGTAGCAAC 17 V_ZNF219_01_M01122 TRANSFAC + 77045495 77045506 8.0E-06 CGCCCCCACCCC 12 V_SOX7_03_M02807 TRANSFAC - 77043464 77043485 5.0E-06 CAACAAATACAATTGAAGTTTT 22 V_RXRA_03_M02791 TRANSFAC + 77043338 77043354 0.0E+00 CTCCTTGACCCCTTATT 17 V_IRF2_01_M00063 TRANSFAC + 77046334 77046346 6.0E-06 GAAAACTGAATCT 13 V_SP4_03_M02810 TRANSFAC + 77045725 77045741 1.0E-06 GCTCCCGCCCCCTCTTT 17 V_KROX_Q6_M00982 TRANSFAC + 77045493 77045506 0.0E+00 CCCGCCCCCACCCC 14 V_MAZ_Q6_01_M02023 TRANSFAC - 77045488 77045501 1.0E-05 GGGGGCGGGGAGTG 14 V_HNF3_Q6_M00791 TRANSFAC - 77043475 77043487 6.0E-06 ATCAACAAATACA 13 V_IRF_Q6_M00772 TRANSFAC - 77046335 77046349 6.0E-06 TTAAGATTCAGTTTT 15 V_GADP_01_M01258 TRANSFAC + 77045539 77045550 8.0E-06 CGCTTCCGGCCC 12 V_OCT1_04_M00138 TRANSFAC + 77043478 77043500 1.0E-06 ATTTGTTGATGTAAAAACATTAA 23 V_SP1SP3_Q4_M01219 TRANSFAC + 77045729 77045739 5.0E-06 CCGCCCCCTCT 11 V_SP1SP3_Q4_M01219 TRANSFAC + 77045750 77045760 8.0E-06 CCGCCCCCTGC 11 V_PEBP_Q6_M00984 TRANSFAC + 77046115 77046129 1.0E-06 GGTCACCACAGAAGT 15 V_PNR_01_M01650 TRANSFAC + 77044795 77044808 9.0E-06 AGGCTCAAAAGTCA 14 V_SP1_01_M00008 TRANSFAC + 77045869 77045878 3.0E-06 GGGGCGGGGT 10 V_MAF_Q6_01_M00983 TRANSFAC - 77043389 77043399 6.0E-06 GGCTGAGTCAG 11 V_SP4_Q5_M01273 TRANSFAC + 77045491 77045501 9.0E-06 TCCCCGCCCCC 11 V_SP4_Q5_M01273 TRANSFAC + 77045747 77045757 5.0E-06 CCCCCGCCCCC 11 V_HFH8_01_M00294 TRANSFAC - 77045019 77045031 4.0E-06 ACGTGTTTATGTG 13 V_FOXL1_04_M02753 TRANSFAC - 77043476 77043492 1.0E-05 TTTACATCAACAAATAC 17 NR1H2_RXRA_MA0115.1 JASPAR + 77044794 77044810 5.0E-06 AAGGCTCAAAAGTCACT 17 V_FOXO3_01_M00477 TRANSFAC + 77043477 77043490 9.0E-06 TATTTGTTGATGTA 14 V_ZFP281_01_M01597 TRANSFAC - 77045492 77045502 6.0E-06 TGGGGGCGGGG 11 V_BBX_03_M02739 TRANSFAC + 77044631 77044645 0.0E+00 AAATTCACTGAAGTG 15 V_BBX_03_M02739 TRANSFAC - 77044631 77044645 3.0E-06 CACTTCAGTGAATTT 15 V_EGR1_06_M02744 TRANSFAC + 77045728 77045741 1.0E-06 CCCGCCCCCTCTTT 14 V_OCT1_07_M00248 TRANSFAC - 77043378 77043389 7.0E-06 GCCATGGAAATT 12 V_HFH3_01_M00289 TRANSFAC + 77043474 77043486 6.0E-06 TTGTATTTGTTGA 13 V_FOXJ2_01_M00422 TRANSFAC - 77043472 77043489 4.0E-06 ACATCAACAAATACAATT 18 V_EKLF_Q5_M01874 TRANSFAC - 77045357 77045366 5.0E-06 CCACACCCAG 10 V_HOXB3_01_M01330 TRANSFAC + 77046190 77046206 4.0E-06 TAAGGTAATGAGTAGCA 17 V_GMEB1_04_M02865 TRANSFAC - 77045022 77045037 8.0E-06 TGCGAGACGTGTTTAT 16 V_SP1_Q2_01_M00933 TRANSFAC + 77045492 77045501 4.0E-06 CCCCGCCCCC 10 V_SP1_Q2_01_M00933 TRANSFAC + 77045748 77045757 4.0E-06 CCCCGCCCCC 10 V_FOXO4_01_M00472 TRANSFAC + 77045022 77045032 1.0E-05 ATAAACACGTC 11 V_UF1H3BETA_Q6_M01068 TRANSFAC - 77045491 77045504 3.0E-06 GGTGGGGGCGGGGA 14 V_UF1H3BETA_Q6_M01068 TRANSFAC - 77045741 77045754 6.0E-06 GGCGGGGGAGAGGA 14 V_PBX1_04_M01357 TRANSFAC - 77043477 77043493 3.0E-06 TTTTACATCAACAAATA 17 V_ZIC2_04_M02836 TRANSFAC - 77045163 77045177 9.0E-06 ACCTCCCGGGGGGTT 15 V_AR_01_M00481 TRANSFAC + 77045044 77045058 7.0E-06 GGGACAAACTGTTCC 15 V_AR_01_M00481 TRANSFAC - 77045044 77045058 7.0E-06 GGAACAGTTTGTCCC 15

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