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TSPEAR Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 54084 thrombospondin-type laminin G domain and EAR repeats chr21 - 46130995 - 46136495 46131495 Transcription Factor Binding Sites   Download all TFBS in the TSPEAR promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints SOX10_HMG_full_dimeric_15_3 SELEX - 46129972 46129986 1.0E-05 ATGAGTCACAGACAT 15 MEF2D_MADS_DBD_dimeric_12_1 SELEX + 46129901 46129912 6.0E-06 TTTATAAATAAC 12 NR2E1_nuclearreceptor_full_monomeric_9_1 SELEX - 46129808 46129816 2.0E-06 AAAAGTCAA 9 Tp53_p53l_DBD_dimeric_18_2 SELEX + 46129959 46129976 7.0E-06 AACATGAAAATACATGTC 18 Tp53_p53l_DBD_dimeric_18_2 SELEX - 46129959 46129976 6.0E-06 GACATGTATTTTCATGTT 18 EWSR1-FLI1_MA0149.1 JASPAR + 46132748 46132765 0.0E+00 GGAGGGAGGGAAGGAGAA 18 ZNF232_C2H2_full_monomeric_19_1 SELEX - 46129848 46129866 8.0E-06 TAGTTAAAAGATGACCCAG 19 Tp73_p53l_DBD_dimeric_18_1 SELEX + 46129959 46129976 9.0E-06 AACATGAAAATACATGTC 18 Tp73_p53l_DBD_dimeric_18_1 SELEX - 46129959 46129976 4.0E-06 GACATGTATTTTCATGTT 18 MEF2A_MADS_DBD_dimeric_12_1 SELEX + 46129901 46129912 3.0E-06 TTTATAAATAAC 12 TCF7L1_HMG_full_monomeric_12_1 SELEX - 46129811 46129822 4.0E-06 AAAGATAAAAGT 12 LEF1_HMG_DBD_monomeric_15_1 SELEX - 46129808 46129822 2.0E-06 AAAGATAAAAGTCAA 15 Rfx3_RFX_DBD_dimeric_16_1 SELEX - 46131131 46131146 5.0E-06 AGTTGCAATAGAAACG 16 POU3F3_POU_DBD_monomeric_13_1 SELEX + 46128478 46128490 1.0E-05 AAGATGCAAATCT 13 Sox17_HMG_DBD_dimeric_15_2 SELEX - 46129972 46129986 8.0E-06 ATGAGTCACAGACAT 15 MEF2A_MA0052.1 JASPAR - 46129902 46129911 4.0E-06 TTATTTATAA 10 FOXO4_forkhead_DBD_putatively-multimeric_12_1 SELEX - 46130883 46130894 6.0E-06 CTTCCCCACATG 12 BARHL2_homeodomain_full_monomeric_10_1 SELEX - 46128496 46128505 9.0E-06 AATAAATGAT 10 Tcf7_HMG_DBD_monomeric_12_1 SELEX - 46129811 46129822 3.0E-06 AAAGATAAAAGT 12 JDP2_bZIP_full_dimeric_9_1 SELEX - 46129978 46129986 1.0E-05 ATGAGTCAC 9 Pou5f1_MA0142.1 JASPAR + 46128474 46128488 0.0E+00 TTTTAAGATGCAAAT 15 Pou5f1_MA0142.1 JASPAR + 46129919 46129933 3.0E-06 TATTATTATGCAGGT 15 FOXO3_forkhead_full_putatively-multimeric_11_1 SELEX - 46130884 46130894 9.0E-06 CTTCCCCACAT 11 Zfp740_C2H2_DBD_monomeric_10_1 SELEX + 46129987 46129996 1.0E-05 GCCCCCCCAC 10 FOXC1_MA0032.1 JASPAR - 46129801 46129808 7.0E-06 AGTAAGTA 8 FOXO6_forkhead_DBD_putatively-multimeric_14_1 SELEX - 46130881 46130894 4.0E-06 CTTCCCCACATGAG 14 FOXO1_forkhead_DBD_putatively-multimeric_12_1 SELEX - 46130883 46130894 4.0E-06 CTTCCCCACATG 12 Sox2_MA0143.1 JASPAR + 46128473 46128487 9.0E-06 CTTTTAAGATGCAAA 15 TP63_p53l_DBD_dimeric_18_1 SELEX + 46129959 46129976 4.0E-06 AACATGAAAATACATGTC 18 RORA_2_MA0072.1 JASPAR + 46129843 46129856 1.0E-06 TATAACTGGGTCAT 14 FOXJ2_forkhead_DBD_dimeric_14_1 SELEX - 46129858 46129871 1.0E-05 GCAAATAGTTAAAA 14 V_CDX2_Q5_01_M01659 TRANSFAC + 46129901 46129911 1.0E-06 TTTATAAATAA 11 V_BACH2_01_M00490 TRANSFAC - 46129977 46129987 8.0E-06 CATGAGTCACA 11 V_SOX40_04_M02908 TRANSFAC + 46129916 46129931 8.0E-06 TATTATTATTATGCAG 16 V_SRY_07_M02813 TRANSFAC + 46129913 46129928 4.0E-06 CTGTATTATTATTATG 16 V_SRY_07_M02813 TRANSFAC - 46129913 46129928 4.0E-06 CATAATAATAATACAG 16 V_SRY_07_M02813 TRANSFAC + 46129916 46129931 6.0E-06 TATTATTATTATGCAG 16 V_SRY_07_M02813 TRANSFAC - 46129916 46129931 3.0E-06 CTGCATAATAATAATA 16 V_GATA2_02_M00348 TRANSFAC - 46129813 46129822 8.0E-06 AAAGATAAAA 10 V_RORA1_01_M00156 TRANSFAC + 46129844 46129856 4.0E-06 ATAACTGGGTCAT 13 V_HP1SITEFACTOR_Q6_M00725 TRANSFAC - 46129857 46129868 2.0E-06 AATAGTTAAAAG 12 V_MMEF2_Q6_M00405 TRANSFAC + 46129898 46129913 0.0E+00 GGCTTTATAAATAACC 16 V_GATA3_03_M00351 TRANSFAC - 46129813 46129822 4.0E-06 AAAGATAAAA 10 V_POU5F1_02_M02245 TRANSFAC + 46128474 46128488 0.0E+00 TTTTAAGATGCAAAT 15 V_POU5F1_02_M02245 TRANSFAC + 46129919 46129933 3.0E-06 TATTATTATGCAGGT 15 V_RORA_Q4_M01138 TRANSFAC + 46129845 46129855 1.0E-06 TAACTGGGTCA 11 V_MEF2_02_M00231 TRANSFAC + 46129895 46129916 7.0E-06 GAGGGCTTTATAAATAACCTGT 22 V_ZFP740_03_M02834 TRANSFAC + 46129990 46130005 3.0E-06 CCCCCACCCCCACTCC 16 V_FOXO3A_Q1_M01137 TRANSFAC + 46129903 46129914 9.0E-06 TATAAATAACCT 12 V_P50P50_Q3_M01223 TRANSFAC + 46134885 46134897 6.0E-06 AAGGGAATTCACG 13 V_MAF_Q6_M00648 TRANSFAC - 46129336 46129351 9.0E-06 TTTGGGGAAGTTGTGG 16 V_SP1_02_M01303 TRANSFAC - 46129989 46129999 5.0E-06 GGGGTGGGGGG 11 V_SOX21_03_M02803 TRANSFAC + 46129913 46129928 1.0E-06 CTGTATTATTATTATG 16 V_SOX21_03_M02803 TRANSFAC - 46129913 46129928 1.0E-06 CATAATAATAATACAG 16 V_SOX21_03_M02803 TRANSFAC + 46129916 46129931 5.0E-06 TATTATTATTATGCAG 16 V_SOX21_03_M02803 TRANSFAC - 46129916 46129931 2.0E-06 CTGCATAATAATAATA 16 V_MEF2A_Q6_M02024 TRANSFAC + 46129839 46129848 3.0E-06 TATTTATAAC 10 V_MEF2A_Q6_M02024 TRANSFAC - 46129901 46129910 2.0E-06 TATTTATAAA 10 V_CP2_02_M00947 TRANSFAC + 46131079 46131093 0.0E+00 GCTGGTTAGCTCTTG 15 V_FOXA2_02_M02853 TRANSFAC - 46129911 46129925 9.0E-06 AATAATAATACAGGT 15 V_OCT1_03_M00137 TRANSFAC - 46129918 46129930 4.0E-06 TGCATAATAATAA 13 V_KROX_Q6_M00982 TRANSFAC + 46129992 46130005 1.0E-05 CCCACCCCCACTCC 14 V_P53_03_M01651 TRANSFAC + 46129958 46129977 1.0E-06 GAACATGAAAATACATGTCT 20 V_P53_03_M01651 TRANSFAC - 46129958 46129977 1.0E-06 AGACATGTATTTTCATGTTC 20 V_RSRFC4_Q2_M00407 TRANSFAC + 46129899 46129915 3.0E-06 GCTTTATAAATAACCTG 17 V_AMEF2_Q6_M00403 TRANSFAC + 46129898 46129915 6.0E-06 GGCTTTATAAATAACCTG 18 V_FOXK1_04_M02856 TRANSFAC - 46129913 46129927 6.0E-06 ATAATAATAATACAG 15 V_MAZ_Q6_01_M02023 TRANSFAC + 46132749 46132762 1.0E-06 GAGGGAGGGAAGGA 14 V_PAX5_01_M00143 TRANSFAC - 46128451 46128478 3.0E-06 TAAAAGATCACTGGGGTGTGGAGGCTGC 28 V_MEF2_03_M00232 TRANSFAC + 46129895 46129916 8.0E-06 GAGGGCTTTATAAATAACCTGT 22 V_JUNDM2_04_M02876 TRANSFAC - 46129975 46129990 9.0E-06 GGGCATGAGTCACAGA 16 V_BBX_04_M02843 TRANSFAC - 46129853 46129869 1.0E-06 AAATAGTTAAAAGATGA 17 V_BBX_04_M02843 TRANSFAC + 46134874 46134890 8.0E-06 GCATTGTTAACAAGGGA 17 V_TAXCREB_02_M00115 TRANSFAC + 46129978 46129992 5.0E-06 GTGACTCATGCCCCC 15 V_XFD2_01_M00268 TRANSFAC + 46129901 46129914 4.0E-06 TTTATAAATAACCT 14 V_MEF2_Q6_01_M00941 TRANSFAC - 46129902 46129913 2.0E-06 GGTTATTTATAA 12 V_TBP_06_M02814 TRANSFAC + 46129899 46129914 6.0E-06 GCTTTATAAATAACCT 16 V_IRX5_01_M01472 TRANSFAC + 46129965 46129981 5.0E-06 AAAATACATGTCTGTGA 17 V_GATA4_Q3_M00632 TRANSFAC - 46129809 46129820 2.0E-06 AGATAAAAGTCA 12 V_TBP_01_M00471 TRANSFAC - 46129839 46129846 4.0E-06 TATAAATA 8 V_TBP_01_M00471 TRANSFAC + 46129903 46129910 4.0E-06 TATAAATA 8 V_GATA3_02_M00350 TRANSFAC - 46129813 46129822 3.0E-06 AAAGATAAAA 10 V_PLAG1_01_M01778 TRANSFAC + 46132767 46132782 0.0E+00 GGGGCCGAAGAGAGGG 16 V_TCF7_04_M02921 TRANSFAC + 46129913 46129927 3.0E-06 CTGTATTATTATTAT 15 V_GATA6_01_M00462 TRANSFAC - 46129813 46129822 3.0E-06 AAAGATAAAA 10 V_NKX22_01_M00485 TRANSFAC - 46131053 46131062 1.0E-05 ACAAGTGCTT 10 V_FOXO3_01_M00477 TRANSFAC - 46134876 46134889 9.0E-06 CCCTTGTTAACAAT 14 V_RSRFC4_01_M00026 TRANSFAC + 46129899 46129914 9.0E-06 GCTTTATAAATAACCT 16 V_RSRFC4_01_M00026 TRANSFAC - 46129899 46129914 3.0E-06 AGGTTATTTATAAAGC 16 V_ZFP281_01_M01597 TRANSFAC - 46129991 46130001 1.0E-06 TGGGGGTGGGG 11 V_IRX2_01_M01405 TRANSFAC + 46129965 46129981 3.0E-06 AAAATACATGTCTGTGA 17 V_SOX2_01_M02246 TRANSFAC + 46128473 46128487 9.0E-06 CTTTTAAGATGCAAA 15 V_HFH3_01_M00289 TRANSFAC - 46129901 46129913 8.0E-06 GGTTATTTATAAA 13 V_EWSR1FLI1_01_M02252 TRANSFAC + 46132748 46132765 0.0E+00 GGAGGGAGGGAAGGAGAA 18 V_EKLF_Q5_M01874 TRANSFAC + 46131102 46131111 9.0E-06 CCCCACCCTG 10 V_PPARG_02_M00515 TRANSFAC + 46129787 46129809 2.0E-06 ATGCAGCTCAATATTACTTACTT 23 V_MEF2_01_M00006 TRANSFAC + 46129900 46129915 2.0E-06 CTTTATAAATAACCTG 16 V_MEF2A_05_M01301 TRANSFAC + 46129836 46129847 4.0E-06 TGGTATTTATAA 12 V_MEF2A_05_M01301 TRANSFAC - 46129902 46129913 1.0E-06 GGTTATTTATAA 12 V_HMEF2_Q6_M00406 TRANSFAC + 46129900 46129915 0.0E+00 CTTTATAAATAACCTG 16 V_RORA2_01_M00157 TRANSFAC + 46129844 46129856 2.0E-06 ATAACTGGGTCAT 13 V_SOX14_03_M02798 TRANSFAC + 46129913 46129928 4.0E-06 CTGTATTATTATTATG 16 V_SOX14_03_M02798 TRANSFAC - 46129913 46129928 4.0E-06 CATAATAATAATACAG 16 V_SOX14_03_M02798 TRANSFAC - 46129916 46129931 7.0E-06 CTGCATAATAATAATA 16 V_GATA1_06_M00347 TRANSFAC - 46129813 46129822 1.0E-05 AAAGATAAAA 10 V_OCT4_01_M01125 TRANSFAC + 46128474 46128488 0.0E+00 TTTTAAGATGCAAAT 15 V_OCT4_01_M01125 TRANSFAC + 46129919 46129933 3.0E-06 TATTATTATGCAGGT 15 V_TCF11_01_M00285 TRANSFAC + 46129852 46129864 4.0E-06 GTCATCTTTTAAC 13

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