Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

PITX2 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS Motifs 5308 paired-like homeodomain 2 chr4 - 111562779 - 111568279 111563279 V_PITX2_Q6_M02114 V_PITX2_Q2_M00482 V_PITX2_01_M01447 V_ARP1_01_M00155 Transcription Factor Binding Sites   Download all TFBS in the PITX2 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints NKX2-8_homeodomain_full_monomeric_9_1 SELEX - 111562463 111562471 3.0E-06 CCACTTGAA 9 CTCF_MA0139.1 JASPAR + 111558837 111558855 9.0E-06 AGACCGGTAGAGGGCGGGA 19 Foxa2_MA0047.2 JASPAR - 111561939 111561950 9.0E-06 TATTTACATACT 12 MSX2_homeodomain_DBD_dimeric_18_1 SELEX + 111561129 111561146 2.0E-06 GTATTTAGATTCCGATTA 18 MSX2_homeodomain_DBD_dimeric_18_1 SELEX - 111564393 111564410 2.0E-06 CCAATTATCATGCAAATA 18 BARX1_homeodomain_DBD_dimeric_17_1 SELEX + 111561130 111561146 2.0E-06 TATTTAGATTCCGATTA 17 RARA_nuclearreceptor_full_dimeric_18_1 SELEX + 111559177 111559194 2.0E-06 CAAGTTCACCCTGGGTCA 18 POU5F1P1_POU_DBD_monomeric_9_1 SELEX + 111561941 111561949 3.0E-06 TATGTAAAT 9 ZNF75A_C2H2_DBD_monomeric_12_1 SELEX + 111559611 111559622 3.0E-06 GATTTTCCCACC 12 FOXC1_forkhead_DBD_monomeric_11_1 SELEX + 111561941 111561951 4.0E-06 TATGTAAATAC 11 POU2F3_POU_DBD_monomeric_9_1 SELEX + 111561941 111561949 4.0E-06 TATGTAAAT 9 RARG_nuclearreceptor_full_dimeric_17_1 SELEX + 111559178 111559194 4.0E-06 AAGTTCACCCTGGGTCA 17 POU1F1_POU_DBD_monomeric_14_1 SELEX - 111564391 111564404 2.0E-06 ATCATGCAAATAAG 14 BARX1_homeodomain_DBD_monomeric_8_1 SELEX - 111560210 111560217 5.0E-06 ACAATTAA 8 Rarb_nuclearreceptor_DBD_dimeric_18_1 SELEX + 111559177 111559194 1.0E-06 CAAGTTCACCCTGGGTCA 18 POU2F2_POU_DBD_monomeric_11_1 SELEX + 111560839 111560849 8.0E-06 AAATGCAAATG 11 POU2F2_POU_DBD_monomeric_11_1 SELEX + 111561940 111561950 5.0E-06 GTATGTAAATA 11 POU2F2_POU_DBD_monomeric_11_1 SELEX - 111564393 111564403 8.0E-06 TCATGCAAATA 11 POU3F4_POU_DBD_monomeric_9_1 SELEX + 111560840 111560848 7.0E-06 AATGCAAAT 9 POU3F4_POU_DBD_monomeric_9_1 SELEX + 111561941 111561949 4.0E-06 TATGTAAAT 9 SCRT2_C2H2_DBD_monomeric_13_1 SELEX + 111559171 111559183 5.0E-06 ATTCAACAAGTTC 13 Pou2f2_POU_DBD_monomeric_9_1 SELEX + 111561941 111561949 5.0E-06 TATGTAAAT 9 FOXD2_forkhead_DBD_dimeric_14_1 SELEX - 111559619 111559632 5.0E-06 AATTAATATTGGTG 14 E2F7_E2F_DBD_dimeric_14_1 SELEX + 111559613 111559626 1.0E-06 TTTTCCCACCAATA 14 BARHL2_homeodomain_full_dimeric_16_1 SELEX - 111561141 111561156 7.0E-06 TAATTTGAAGTAATCG 16 GBX2_homeodomain_full_monomeric_10_1 SELEX - 111564402 111564411 8.0E-06 ACCAATTATC 10 Barhl1_homeodomain_DBD_dimeric_16_1 SELEX - 111561141 111561156 8.0E-06 TAATTTGAAGTAATCG 16 POU3F3_POU_DBD_monomeric_13_1 SELEX - 111564392 111564404 4.0E-06 ATCATGCAAATAA 13 FOXD3_forkhead_DBD_dimeric_14_1 SELEX - 111559619 111559632 5.0E-06 AATTAATATTGGTG 14 RARG_nuclearreceptor_DBD_dimeric_17_2 SELEX + 111559178 111559194 1.0E-06 AAGTTCACCCTGGGTCA 17 E2F8_E2F_DBD_dimeric_12_1 SELEX + 111559614 111559625 1.0E-06 TTTCCCACCAAT 12 Lhx8_homeodomain_DBD_dimeric_18_1 SELEX + 111561140 111561157 4.0E-06 CCGATTACTTCAAATTAG 18 Lhx8_homeodomain_DBD_dimeric_18_1 SELEX - 111561140 111561157 5.0E-06 CTAATTTGAAGTAATCGG 18 FOXC1_forkhead_DBD_dimeric_14_1 SELEX - 111559619 111559632 8.0E-06 AATTAATATTGGTG 14 BCL6B_C2H2_DBD_monomeric_17_1 SELEX - 111564472 111564488 1.0E-06 CTCTTGCTAGAAATTCC 17 CTCF_C2H2_full_monomeric_17_1 SELEX - 111558838 111558854 1.0E-05 CCCGCCCTCTACCGGTC 17 Tcf7_HMG_DBD_monomeric_12_1 SELEX + 111558585 111558596 9.0E-06 ATAAATCAAAGG 12 NFATC1_NFAT_full_dimeric_15_1 SELEX + 111558503 111558517 3.0E-06 CTCCCACTGTGGAAA 15 NFATC1_NFAT_full_dimeric_15_1 SELEX - 111558503 111558517 3.0E-06 TTTCCACAGTGGGAG 15 RARG_nuclearreceptor_DBD_dimeric_17_1 SELEX + 111559178 111559194 1.0E-06 AAGTTCACCCTGGGTCA 17 Gata1_MA0035.2 JASPAR - 111561919 111561929 2.0E-06 TCAGATAAGGA 11 MZF1_5-13_MA0057.1 JASPAR + 111560184 111560193 8.0E-06 TGAGGGGGAA 10 ZSCAN4_C2H2_full_monomeric_15_1 SELEX - 111562448 111562462 9.0E-06 TGCACTCACTCACAA 15 Msx3_homeodomain_DBD_dimeric_18_1 SELEX + 111561129 111561146 3.0E-06 GTATTTAGATTCCGATTA 18 Msx3_homeodomain_DBD_dimeric_18_1 SELEX - 111564393 111564410 2.0E-06 CCAATTATCATGCAAATA 18 NKX2-3_homeodomain_full_monomeric_10_1 SELEX - 111562463 111562472 8.0E-06 TCCACTTGAA 10 CART1_homeodomain_DBD_dimeric_13_1 SELEX - 111560210 111560222 9.0E-06 GAAATACAATTAA 13 HESX1_homeodomain_DBD_dimeric_15_1 SELEX + 111564403 111564417 3.0E-06 ATAATTGGTACTTGG 15 POU3F1_POU_DBD_monomeric_12_1 SELEX - 111564392 111564403 8.0E-06 TCATGCAAATAA 12 Hltf_MA0109.1 JASPAR - 111562749 111562758 1.0E-05 TACCTTTTAT 10 Pou5f1_MA0142.1 JASPAR - 111564394 111564408 1.0E-06 AATTATCATGCAAAT 15 POU2F1_POU_DBD_monomeric_12_1 SELEX + 111561939 111561950 2.0E-06 AGTATGTAAATA 12 POU2F1_POU_DBD_monomeric_12_1 SELEX - 111564393 111564404 3.0E-06 ATCATGCAAATA 12 HMX2_homeodomain_DBD_monomeric_11_1 SELEX - 111564401 111564411 7.0E-06 ACCAATTATCA 11 IRF3_IRF_full_trimeric_21_1 SELEX + 111568193 111568213 4.0E-06 TAAGAAAGGAAAAGGAATGAC 21 MSX1_homeodomain_DBD_dimeric_18_1 SELEX + 111561129 111561146 3.0E-06 GTATTTAGATTCCGATTA 18 MSX1_homeodomain_DBD_dimeric_18_1 SELEX - 111564393 111564410 1.0E-06 CCAATTATCATGCAAATA 18 Nobox_MA0125.1 JASPAR + 111564404 111564411 7.0E-06 TAATTGGT 8 Sox2_MA0143.1 JASPAR - 111564395 111564409 4.0E-06 CAATTATCATGCAAA 15 FOXB1_forkhead_DBD_monomeric_11_1 SELEX + 111561941 111561951 1.0E-06 TATGTAAATAC 11 V_RUSH1A_02_M01107 TRANSFAC - 111562749 111562758 1.0E-05 TACCTTTTAT 10 V_CEBPG_Q6_M00622 TRANSFAC + 111561143 111561155 9.0E-06 ATTACTTCAAATT 13 V_STAT5A_Q6_M01890 TRANSFAC + 111564463 111564475 3.0E-06 AACTTTCTTGGAA 13 V_ZFP187_03_M02830 TRANSFAC - 111564404 111564417 8.0E-06 CCAAGTACCAATTA 14 V_GEN_INI_B_M00315 TRANSFAC - 111560181 111560188 1.0E-05 CCTCATTT 8 V_LEF1_04_M02774 TRANSFAC - 111558584 111558600 1.0E-05 TCCCCCTTTGATTTATT 17 V_GATA1_Q6_M02004 TRANSFAC - 111561918 111561932 2.0E-06 TTGTCAGATAAGGAG 15 V_SOX40_04_M02908 TRANSFAC - 111561879 111561894 8.0E-06 TGAGATCATAATCCAG 16 V_FOXA2_04_M02749 TRANSFAC + 111561206 111561222 2.0E-06 CAGATGTAAACAAGATT 17 V_FOXA2_04_M02749 TRANSFAC + 111561939 111561955 1.0E-05 AGTATGTAAATACCAAT 17 V_BCL6B_03_M02740 TRANSFAC + 111564464 111564479 0.0E+00 ACTTTCTTGGAATTTC 16 V_RORA1_01_M00156 TRANSFAC - 111558762 111558774 8.0E-06 GAAAGAAGGTCAC 13 V_BCL6_01_M01183 TRANSFAC - 111568184 111568199 0.0E+00 TTTCTTAAATTGTTTT 16 V_STAT_Q6_M00777 TRANSFAC + 111564462 111564474 1.0E-05 AAACTTTCTTGGA 13 V_POU5F1_02_M02245 TRANSFAC - 111564394 111564408 1.0E-06 AATTATCATGCAAAT 15 V_FOXJ2_02_M00423 TRANSFAC - 111559620 111559633 6.0E-06 GAATTAATATTGGT 14 V_OCT1_Q5_01_M00930 TRANSFAC - 111561941 111561951 9.0E-06 GTATTTACATA 11 V_ZFP740_03_M02834 TRANSFAC - 111559265 111559280 1.0E-06 CCCCCACCCCCACTTC 16 V_OCT1_01_M00135 TRANSFAC + 111561936 111561954 4.0E-06 GCGAGTATGTAAATACCAA 19 V_OCT1_01_M00135 TRANSFAC - 111564389 111564407 5.0E-06 ATTATCATGCAAATAAGGG 19 V_POU2F3_01_M01476 TRANSFAC + 111561938 111561953 6.0E-06 GAGTATGTAAATACCA 16 V_POU2F3_01_M01476 TRANSFAC - 111564390 111564405 2.0E-06 TATCATGCAAATAAGG 16 V_GABPA_04_M02858 TRANSFAC - 111560183 111560198 2.0E-06 GCATTTTCCCCCTCAT 16 V_STAT5B_01_M00459 TRANSFAC + 111564464 111564478 1.0E-06 ACTTTCTTGGAATTT 15 V_P50RELAP65_Q5_01_M01224 TRANSFAC + 111559610 111559621 0.0E+00 GGATTTTCCCAC 12 V_AP2_Q6_M00189 TRANSFAC - 111558350 111558361 4.0E-06 CTCCCCCCGGCG 12 V_OCT_C_M00210 TRANSFAC + 111564391 111564403 1.0E-06 CTTATTTGCATGA 13 V_BCL6_02_M01185 TRANSFAC + 111564463 111564476 0.0E+00 AACTTTCTTGGAAT 14 V_ZNF219_01_M01122 TRANSFAC - 111559271 111559282 1.0E-05 CTCCCCCACCCC 12 V_GEN_INI3_B_M00314 TRANSFAC - 111560181 111560188 1.0E-05 CCTCATTT 8 V_TCF3_04_M02816 TRANSFAC + 111558584 111558600 7.0E-06 AATAAATCAAAGGGGGA 17 V_ZFP410_03_M02832 TRANSFAC + 111558532 111558548 1.0E-06 GAGGATGGGATGGAAGA 17 V_PXRRXR_02_M01153 TRANSFAC - 111560308 111560315 1.0E-05 AGAGTTCA 8 V_IRF3_Q3_M01279 TRANSFAC - 111568197 111568209 2.0E-06 TTCCTTTTCCTTT 13 V_MAZ_Q6_01_M02023 TRANSFAC + 111558821 111558834 8.0E-06 GAGGGAGGAAAGTG 14 V_IRF_Q6_M00772 TRANSFAC - 111568195 111568209 9.0E-06 TTCCTTTTCCTTTCT 15 V_NKX25_Q5_M01043 TRANSFAC - 111562464 111562473 7.0E-06 TTCCACTTGA 10 V_NKX52_01_M01315 TRANSFAC - 111560205 111560221 9.0E-06 AAATACAATTAAACAGC 17 V_NKX52_01_M01315 TRANSFAC + 111568183 111568199 5.0E-06 GAAAACAATTTAAGAAA 17 V_ASCL2_03_M02737 TRANSFAC - 111560822 111560838 5.0E-06 CCCACCAGCTGCTCACT 17 V_IRF3_06_M02871 TRANSFAC + 111558906 111558919 8.0E-06 GAAGAATGGAGTGA 14 V_PAX6_Q2_M00979 TRANSFAC - 111560315 111560328 3.0E-06 GTGTCCTGTAACTA 14 V_OCT1_04_M00138 TRANSFAC + 111561934 111561956 1.0E-05 AAGCGAGTATGTAAATACCAATG 23 V_GATA1_09_M02254 TRANSFAC - 111561919 111561929 2.0E-06 TCAGATAAGGA 11 V_HB24_01_M01399 TRANSFAC + 111558580 111558594 1.0E-05 CCCTAATAAATCAAA 15 V_STAT4_Q5_M02117 TRANSFAC - 111564466 111564475 5.0E-06 TTCCAAGAAA 10 V_TBP_06_M02814 TRANSFAC + 111559203 111559218 5.0E-06 TCATTTTTTAAAATGA 16 V_TBP_06_M02814 TRANSFAC - 111559203 111559218 5.0E-06 TCATTTTAAAAAATGA 16 V_MZF1_02_M00084 TRANSFAC + 111560181 111560193 8.0E-06 AAATGAGGGGGAA 13 V_OCT1_B_M00342 TRANSFAC + 111560840 111560849 5.0E-06 AATGCAAATG 10 V_OCT_Q6_M00795 TRANSFAC - 111561941 111561951 5.0E-06 GTATTTACATA 11 V_FREAC2_01_M00290 TRANSFAC + 111561206 111561221 3.0E-06 CAGATGTAAACAAGAT 16 V_S8_01_M00099 TRANSFAC - 111564400 111564415 4.0E-06 AAGTACCAATTATCAT 16 V_MTF1_06_M02882 TRANSFAC + 111558546 111558559 9.0E-06 AGAGAAGAAAAAGC 14 V_TAL1_01_M01591 TRANSFAC - 111558544 111558556 4.0E-06 TTTTCTTCTCTTC 13 V_OCT2_01_M01368 TRANSFAC + 111561938 111561953 7.0E-06 GAGTATGTAAATACCA 16 V_OCT2_01_M01368 TRANSFAC - 111564390 111564405 1.0E-06 TATCATGCAAATAAGG 16 V_GATA1_04_M00128 TRANSFAC - 111561918 111561930 1.0E-06 GTCAGATAAGGAG 13 V_CACBINDINGPROTEIN_Q6_M00720 TRANSFAC + 111558930 111558938 8.0E-06 GAGGGTGGG 9 V_ZBTB3_03_M02825 TRANSFAC + 111558263 111558279 2.0E-06 AACTCCACTGCACAGTG 1 V_OCT1_Q6_M00195 TRANSFAC + 111560837 111560851 6.0E-06 GGAAATGCAAATGGC 15 V_OCT1_Q6_M00195 TRANSFAC + 111561938 111561952 4.0E-06 GAGTATGTAAATACC 15 V_OCT1_Q6_M00195 TRANSFAC - 111564391 111564405 7.0E-06 TATCATGCAAATAAG 15 V_FOXL1_04_M02753 TRANSFAC + 111561206 111561222 5.0E-06 CAGATGTAAACAAGATT 17 V_MSX2_01_M01393 TRANSFAC - 111564399 111564415 7.0E-06 AAGTACCAATTATCATG 17 V_GEN_INI2_B_M00313 TRANSFAC - 111560181 111560188 1.0E-05 CCTCATTT 8 V_FOXA2_03_M02260 TRANSFAC - 111561939 111561950 9.0E-06 TATTTACATACT 12 V_LMO2COM_02_M00278 TRANSFAC - 111561920 111561928 3.0E-06 CAGATAAGG 9 V_ZFP281_01_M01597 TRANSFAC + 111559269 111559279 1.0E-06 TGGGGGTGGGG 11 V_OCT1_06_M00162 TRANSFAC - 111559197 111559210 7.0E-06 AAAAATGAGATATC 14 V_STAT5A_01_M00457 TRANSFAC + 111564464 111564478 3.0E-06 ACTTTCTTGGAATTT 15 V_SOX14_04_M02901 TRANSFAC - 111559612 111559628 2.0E-06 AATATTGGTGGGAAAAT 17 V_SOX2_01_M02246 TRANSFAC - 111564395 111564409 4.0E-06 CAATTATCATGCAAA 15 V_ZFP281_04_M02831 TRANSFAC - 111559267 111559281 1.0E-05 TCCCCCACCCCCACT 15 V_HFH3_01_M00289 TRANSFAC - 111561941 111561953 5.0E-06 TGGTATTTACATA 13 V_BARHL2_01_M01446 TRANSFAC - 111564400 111564415 6.0E-06 AAGTACCAATTATCAT 16 V_GATA5_03_M02756 TRANSFAC - 111561916 111561932 7.0E-06 TTGTCAGATAAGGAGCT 17 V_HMX3_02_M01413 TRANSFAC + 111568183 111568199 6.0E-06 GAAAACAATTTAAGAAA 17 V_BARX1_01_M01340 TRANSFAC + 111564400 111564415 6.0E-06 ATGATAATTGGTACTT 16 V_HOXD10_01_M01375 TRANSFAC - 111560204 111560220 5.0E-06 AATACAATTAAACAGCA 17 V_SOX5_04_M02910 TRANSFAC - 111561877 111561891 9.0E-06 GATCATAATCCAGAG 15 V_PBX1_Q3_M02028 TRANSFAC + 111558585 111558593 6.0E-06 ATAAATCAA 9 V_DTYPEPA_B_M00334 TRANSFAC - 111560208 111560217 5.0E-06 ACAATTAAAC 10 V_FOXK1_03_M02752 TRANSFAC + 111561206 111561222 1.0E-06 CAGATGTAAACAAGATT 17 V_OCT4_01_M01125 TRANSFAC - 111564394 111564408 0.0E+00 AATTATCATGCAAAT 15

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.