Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

PDHB Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 5162 pyruvate dehydrogenase (lipoamide) beta chr3 - 58419079 - 58424579 58419579 Transcription Factor Binding Sites   Download all TFBS in the PDHB promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints EVX2_homeodomain_DBD_monomeric_10_1 SELEX + 58420531 58420540 1.0E-05 GGTAATTAGA 10 RARB_nuclearreceptor_full_dimeric_16_1 SELEX - 58421434 58421449 0.0E+00 TGAGGTCAAGAGTTCA 16 ALX3_homeodomain_full_monomeric_10_1 SELEX - 58420531 58420540 1.0E-05 TCTAATTACC 10 FOXA1_MA0148.1 JASPAR + 58423320 58423330 9.0E-06 TGTTTGTTTTG 11 LHX6_homeodomain_full_dimeric_16_1 SELEX - 58420523 58420538 2.0E-06 TAATTACCGGTGCTTG 16 LHX6_homeodomain_full_dimeric_16_1 SELEX + 58420805 58420820 5.0E-06 TCATTAGTCTTAATTT 16 LHX6_homeodomain_full_dimeric_16_1 SELEX - 58420805 58420820 9.0E-06 AAATTAAGACTAATGA 16 PDX1_homeodomain_DBD_dimeric_18_1 SELEX + 58420804 58420821 1.0E-06 CTCATTAGTCTTAATTTG 18 PDX1_homeodomain_DBD_dimeric_18_1 SELEX - 58420804 58420821 1.0E-06 CAAATTAAGACTAATGAG 18 NR2F1_nuclearreceptor_DBD_monomeric_13_1 SELEX - 58421438 58421450 8.0E-06 TTGAGGTCAAGAG 13 FOXL1_forkhead_full_dimeric_13_1 SELEX - 58423319 58423331 4.0E-06 TCAAAACAAACAA 13 SOX8_HMG_full_dimeric_17_1 SELEX + 58419736 58419752 3.0E-06 AATCAACTTTATTGACA 17 Alx1_homeodomain_DBD_monomeric_10_1 SELEX - 58420531 58420540 1.0E-05 TCTAATTACC 10 SOX7_HMG_full_dimeric_17_2 SELEX + 58423085 58423101 4.0E-06 GGAAAATTACAGTCAAA 17 STAT1_MA0137.2 JASPAR + 58415663 58415677 4.0E-06 GCCTTCCTAGAAATG 15 GLIS1_C2H2_DBD_monomeric_16_1 SELEX - 58423122 58423137 8.0E-06 TGACCCCCCACTTCTG 16 Pax4_MA0068.1 JASPAR - 58421203 58421232 2.0E-06 AACAAAAATACACTCTTACTTCCCCAGCTC 30 Pax4_MA0068.1 JASPAR - 58421208 58421237 1.0E-06 AAATAAACAAAAATACACTCTTACTTCCCC 30 Pax4_MA0068.1 JASPAR - 58421209 58421238 7.0E-06 AAAATAAACAAAAATACACTCTTACTTCCC 30 Pax4_MA0068.1 JASPAR - 58421210 58421239 2.0E-06 AAAAATAAACAAAAATACACTCTTACTTCC 30 Pax4_MA0068.1 JASPAR - 58421211 58421240 0.0E+00 AAAAAATAAACAAAAATACACTCTTACTTC 30 SRF_MA0083.1 JASPAR - 58420437 58420448 6.0E-06 GCCCTTAAAAGG 12 TEAD1_TEA_full_monomeric_10_1 SELEX - 58415650 58415659 7.0E-06 CACATTCCTC 10 Foxc1_forkhead_DBD_dimeric_11_1 SELEX - 58423320 58423330 1.0E-05 CAAAACAAACA 11 Lhx8_homeodomain_DBD_dimeric_18_1 SELEX + 58420804 58420821 5.0E-06 CTCATTAGTCTTAATTTG 18 Lhx8_homeodomain_DBD_dimeric_18_1 SELEX - 58420804 58420821 1.0E-06 CAAATTAAGACTAATGAG 18 FOXI1_MA0042.1 JASPAR + 58423317 58423328 1.0E-06 TCTTGTTTGTTT 12 NFAT5_NFAT_DBD_dimeric_14_1 SELEX + 58423083 58423096 0.0E+00 GTGGAAAATTACAG 14 HEY1_bHLH_DBD_dimeric_10_1 SELEX + 58419788 58419797 8.0E-06 CACACGTGCC 10 YY2_C2H2_full_monomeric_11_1 SELEX + 58419529 58419539 4.0E-06 GCCGCCATCTT 11 FOXC2_forkhead_DBD_dimeric_11_1 SELEX - 58423320 58423330 6.0E-06 CAAAACAAACA 11 NR2F1_nuclearreceptor_DBD_dimeric_16_1 SELEX - 58421433 58421448 0.0E+00 GAGGTCAAGAGTTCAA 16 VENTX_homeodomain_DBD_monomeric_9_1 SELEX + 58420606 58420614 5.0E-06 ACCGATTAG 9 TEAD3_TEA_DBD_dimeric_17_1 SELEX + 58420876 58420892 0.0E+00 ACATTCCAAACATTCCC 17 TBX20_TBX_full_dimeric_16_1 SELEX - 58423305 58423320 3.0E-06 AAGAGTGATGGTGTCA 16 TEAD3_TEA_DBD_monomeric_8_1 SELEX + 58420876 58420883 1.0E-05 ACATTCCA 8 Stat3_MA0144.1 JASPAR - 58415665 58415674 7.0E-06 TTCTAGGAAG 10 Myf_MA0055.1 JASPAR + 58419208 58419219 9.0E-06 AGGCAGCAGGAG 12 TEAD1_TEA_full_dimeric_17_1 SELEX + 58420876 58420892 0.0E+00 ACATTCCAAACATTCCC 17 TEAD4_TEA_DBD_monomeric_10_1 SELEX - 58415650 58415659 9.0E-06 CACATTCCTC 10 IRF3_IRF_full_trimeric_21_1 SELEX + 58415669 58415689 8.0E-06 CTAGAAATGAAACACAAACCT 21 Nr2f6_nuclearreceptor_DBD_dimeric_15_1 SELEX - 58421434 58421448 0.0E+00 GAGGTCAAGAGTTCA 15 RARG_nuclearreceptor_full_dimeric_16_1 SELEX - 58421433 58421448 0.0E+00 GAGGTCAAGAGTTCAA 16 RARA_nuclearreceptor_full_dimeric_15_1 SELEX - 58421434 58421448 1.0E-06 GAGGTCAAGAGTTCA 15 PAX7_PAX_full_dimeric_10_1 SELEX + 58420604 58420613 1.0E-05 TAACCGATTA 10 TEAD1_MA0090.1 JASPAR - 58415648 58415659 1.0E-06 CACATTCCTCAG 12 V_DMRT4_01_M01149 TRANSFAC - 58420928 58420940 9.0E-06 GAAGTTGCAAATT 13 V_NFAT_Q4_01_M00935 TRANSFAC + 58423083 58423092 0.0E+00 GTGGAAAATT 10 V_FOXP1_01_M00987 TRANSFAC - 58418827 58418846 7.0E-06 TCATTTGTCCTTTTGTGTCT 20 V_FOXP1_01_M00987 TRANSFAC - 58423390 58423409 7.0E-06 TTGTTTTTAAGTTTGTTTCT 20 V_SRF_Q6_M00186 TRANSFAC + 58420916 58420929 3.0E-06 TGCCAAATTAGGAA 14 V_STAT5A_Q6_M01890 TRANSFAC - 58415666 58415678 0.0E+00 TCATTTCTAGGAA 13 V_FOXP3_Q4_M00992 TRANSFAC - 58418824 58418840 6.0E-06 GTCCTTTTGTGTCTGGC 17 V_BCL6_Q3_01_M02085 TRANSFAC + 58415665 58415674 2.0E-06 CTTCCTAGAA 10 V_BCL6_Q3_01_M02085 TRANSFAC - 58415667 58415676 5.0E-06 ATTTCTAGGA 10 V_BTEB3_Q5_M01865 TRANSFAC + 58421169 58421181 3.0E-06 GTAAGGGAGGAGC 13 V_SMAD3_Q6_01_M01888 TRANSFAC + 58418823 58418835 6.0E-06 AGCCAGACACAAA 13 V_YY1_02_M00069 TRANSFAC + 58419527 58419546 4.0E-06 CCGCCGCCATCTTGGTCGTG 20 V_DMRT3_01_M01148 TRANSFAC + 58419081 58419095 7.0E-06 ATTTTGCTGCAATTT 15 V_SREBP2_Q6_M01177 TRANSFAC - 58419688 58419699 8.0E-06 ACGCCACCTCAG 12 V_FOXD3_01_M00130 TRANSFAC + 58423317 58423328 9.0E-06 TCTTGTTTGTTT 12 V_STAT_Q6_M00777 TRANSFAC - 58415667 58415679 5.0E-06 TTCATTTCTAGGA 13 V_MAFB_03_M02879 TRANSFAC - 58419081 58419095 5.0E-06 AAATTGCAGCAAAAT 15 V_MAFB_03_M02879 TRANSFAC + 58423383 58423397 3.0E-06 AAATTGCAGAAACAA 15 V_IRF_Q6_01_M00972 TRANSFAC + 58415671 58415681 7.0E-06 AGAAATGAAAC 11 V_NFAT3_Q3_M01734 TRANSFAC - 58423084 58423093 7.0E-06 TAATTTTCCA 10 V_YY1_Q6_M00793 TRANSFAC + 58419532 58419540 7.0E-06 GCCATCTTG 9 V_AP4_Q6_02_M01860 TRANSFAC + 58420904 58420916 4.0E-06 ACAGCTGCAGGCT 13 V_EVX1_01_M01475 TRANSFAC - 58420799 58420815 9.0E-06 AAGACTAATGAGCTTCC 17 V_NFAT2_01_M01748 TRANSFAC + 58423083 58423091 8.0E-06 GTGGAAAAT 9 V_TCFAP2E_04_M02926 TRANSFAC + 58419094 58419107 8.0E-06 TTAAAGAAAAAAAC 14 V_TCFAP2E_04_M02926 TRANSFAC + 58419095 58419108 9.0E-06 TAAAGAAAAAAACA 14 V_LHX8_01_M01440 TRANSFAC - 58420527 58420543 9.0E-06 CAGTCTAATTACCGGTG 17 V_STAT4_Q4_M01666 TRANSFAC + 58415666 58415679 2.0E-06 TTCCTAGAAATGAA 14 V_HMGA2_01_M01300 TRANSFAC - 58419081 58419095 9.0E-06 AAATTGCAGCAAAAT 15 V_ELF4_04_M02850 TRANSFAC + 58419093 58419109 2.0E-06 TTTAAAGAAAAAAACAT 17 V_GC_01_M00255 TRANSFAC - 58419595 58419608 3.0E-06 TGGAGGCGGGGCCT 14 V_MYF_01_M01302 TRANSFAC + 58419208 58419219 9.0E-06 AGGCAGCAGGAG 12 V_GCM1_04_M02862 TRANSFAC - 58420749 58420765 9.0E-06 TCCCCATAAGGGAGGAG 17 V_ZFP105_03_M02827 TRANSFAC - 58423316 58423330 9.0E-06 CAAAACAAACAAGAG 15 V_HNF3G_Q4_M02015 TRANSFAC + 58423320 58423327 7.0E-06 TGTTTGTT 8 V_STAF_01_M00262 TRANSFAC - 58419770 58419791 8.0E-06 TGTGCCCAGCGTGCACCCCGCC 22 V_NFAT_Q6_M00302 TRANSFAC + 58423081 58423092 1.0E-06 TAGTGGAAAATT 12 V_HIC1_03_M01073 TRANSFAC + 58419771 58419788 4.0E-06 GCGGGGTGCACGCTGGGC 18 V_PXRRXR_02_M01153 TRANSFAC - 58421434 58421441 1.0E-05 AGAGTTCA 8 V_IK1_01_M00086 TRANSFAC + 58419462 58419474 5.0E-06 GCGTGGGAATACA 13 V_MAZ_Q6_01_M02023 TRANSFAC - 58419318 58419331 6.0E-06 GAGGGCGGGGAGGG 14 V_HNF3_Q6_M00791 TRANSFAC - 58423318 58423330 3.0E-06 CAAAACAAACAAG 13 V_HNF3ALPHA_Q6_M00724 TRANSFAC + 58423320 58423330 1.0E-06 TGTTTGTTTTG 11 V_IRF_Q6_M00772 TRANSFAC - 58415671 58415685 1.0E-06 TTGTGTTTCATTTCT 15 V_LXR_DR4_Q3_M00766 TRANSFAC + 58421442 58421457 6.0E-06 TGACCTCAAGTGATCC 16 V_TTF1_Q6_M00794 TRANSFAC + 58421444 58421455 7.0E-06 ACCTCAAGTGAT 12 V_BCL6_Q3_M01171 TRANSFAC - 58415667 58415676 5.0E-06 ATTTCTAGGA 10 V_MEF2_03_M00232 TRANSFAC + 58415445 58415466 6.0E-06 ACTCCTTCTTTAGATAGCACTG 22 V_MEF2_03_M00232 TRANSFAC - 58419085 58419106 2.0E-06 TTTTTTTCTTTAAATTGCAGCA 22 V_ISRE_01_M00258 TRANSFAC - 58415497 58415511 1.0E-05 TGGTTTCCCATTCAA 15 V_SFPI1_04_M02896 TRANSFAC + 58419090 58419103 2.0E-06 CAATTTAAAGAAAA 14 V_GLIS2_03_M02759 TRANSFAC - 58423125 58423140 2.0E-06 TTGTGACCCCCCACTT 16 V_YY1_Q6_02_M01035 TRANSFAC + 58419529 58419539 7.0E-06 GCCGCCATCTT 11 V_REX1_03_M01744 TRANSFAC - 58419528 58419539 1.0E-06 AAGATGGCGGCG 12 V_HBP1_03_M02762 TRANSFAC - 58415604 58415619 1.0E-06 TTTATGAATGAACAAG 16 V_HBP1_03_M02762 TRANSFAC + 58423267 58423282 5.0E-06 CATCTGAATGAATACG 16 V_ZBRK1_01_M01105 TRANSFAC + 58415485 58415499 5.0E-06 GGCCCACAGGTCTTG 15 V_MEF2_04_M00233 TRANSFAC - 58419085 58419106 5.0E-06 TTTTTTTCTTTAAATTGCAGCA 22 V_TEF_01_M01305 TRANSFAC - 58415648 58415659 1.0E-06 CACATTCCTCAG 12 V_PNR_01_M01650 TRANSFAC + 58415545 58415558 1.0E-06 CAGATCAGAGATCA 14 V_PNR_01_M01650 TRANSFAC + 58423335 58423348 5.0E-06 GCAGTCAGAGATCA 14 V_HFH1_01_M00129 TRANSFAC + 58423317 58423328 9.0E-06 TCTTGTTTGTTT 12 V_NKX3A_01_M00451 TRANSFAC - 58419024 58419035 4.0E-06 CATTAAGTACAT 12 V_STAT3_03_M01595 TRANSFAC - 58415661 58415676 4.0E-06 ATTTCTAGGAAGGCTG 16 V_SRF_03_M01304 TRANSFAC - 58420890 58420902 5.0E-06 ATCCATAGAAGGG 13 V_FOXO1_Q5_M01216 TRANSFAC - 58423322 58423330 8.0E-06 CAAAACAAA 9 V_SOX17_04_M02904 TRANSFAC + 58415605 58415621 9.0E-06 TTGTTCATTCATAAAGT 17 V_ZNF515_01_M01231 TRANSFAC + 58423127 58423136 4.0E-06 GTGGGGGGTC 10 V_YY1_03_M02044 TRANSFAC + 58419529 58419540 1.0E-06 GCCGCCATCTTG 12 V_HAND1E47_01_M00222 TRANSFAC - 58418821 58418836 1.0E-06 TTTTGTGTCTGGCTTA 16 V_POU6F1_02_M01462 TRANSFAC - 58420799 58420815 4.0E-06 AAGACTAATGAGCTTCC 17 V_HIF1_Q3_M00797 TRANSFAC + 58423276 58423289 9.0E-06 GAATACGTGCAGGC 14 V_FAC1_01_M00456 TRANSFAC - 58423320 58423333 8.0E-06 GCTCAAAACAAACA 14 V_BARHL1_01_M01332 TRANSFAC + 58420602 58420617 1.0E-05 CATAACCGATTAGGTC 16 V_FOXL1_02_M02857 TRANSFAC - 58423319 58423334 7.0E-06 TGCTCAAAACAAACAA 16 V_NCX_01_M00484 TRANSFAC + 58420530 58420539 8.0E-06 CGGTAATTAG 10 V_TEF1_Q6_03_M01817 TRANSFAC + 58415650 58415658 3.0E-06 GAGGAATGT 9 V_TCF7L2_04_M02922 TRANSFAC - 58420479 58420494 8.0E-06 CTCAATCAATCATGAC 16 V_SMAD3_03_M02794 TRANSFAC + 58418820 58418836 1.0E-06 ATAAGCCAGACACAAAA 17 V_SRF_01_M00152 TRANSFAC + 58420887 58420904 8.0E-06 ATTCCCTTCTATGGATCA 18 V_STAT1STAT1_Q3_M01212 TRANSFAC - 58415664 58415676 6.0E-06 ATTTCTAGGAAGG 13 V_PBX1_02_M00124 TRANSFAC - 58420479 58420493 8.0E-06 TCAATCAATCATGAC 15 V_TBP_04_M02918 TRANSFAC + 58420436 58420450 1.0E-06 CCCTTTTAAGGGCTC 15 V_T3RBETA_Q6_01_M02119 TRANSFAC - 58421441 58421457 5.0E-06 GGATCACTTGAGGTCAA 17 V_SRF_Q5_01_M00922 TRANSFAC - 58420886 58420900 7.0E-06 CCATAGAAGGGAATG 15 V_SRF_Q4_M00810 TRANSFAC - 58420884 58420901 8.0E-06 TCCATAGAAGGGAATGTT 18 V_SRF_Q4_M00810 TRANSFAC + 58420917 58420934 7.0E-06 GCCAAATTAGGAATTTGC 18 V_SRF_02_M01257 TRANSFAC - 58420885 58420902 3.0E-06 ATCCATAGAAGGGAATGT 18 V_SRF_02_M01257 TRANSFAC + 58420916 58420933 3.0E-06 TGCCAAATTAGGAATTTG 18 V_SRF_06_M02916 TRANSFAC + 58419092 58419108 1.0E-06 ATTTAAAGAAAAAAACA 17 V_SRF_06_M02916 TRANSFAC + 58419093 58419109 1.0E-06 TTTAAAGAAAAAAACAT 17 V_SRF_06_M02916 TRANSFAC + 58419094 58419110 6.0E-06 TTAAAGAAAAAAACATG 17 V_HFH3_01_M00289 TRANSFAC + 58423317 58423329 1.0E-06 TCTTGTTTGTTTT 13 V_POU6F1_03_M01479 TRANSFAC - 58420799 58420815 5.0E-06 AAGACTAATGAGCTTCC 17 V_FOXJ2_01_M00422 TRANSFAC - 58423315 58423332 6.0E-06 CTCAAAACAAACAAGAGT 18 V_COREBINDINGFACTOR_Q6_M00722 TRANSFAC - 58415506 58415513 1.0E-05 TGTGGTTT 8 V_HNF3B_Q6_M02014 TRANSFAC + 58423319 58423327 1.0E-05 TTGTTTGTT 9 V_ARP1_01_M00155 TRANSFAC + 58421434 58421449 0.0E+00 TGAACTCTTGACCTCA 16 V_LPOLYA_B_M00318 TRANSFAC - 58419742 58419749 7.0E-06 CAATAAAG 8 V_HOXD10_01_M01375 TRANSFAC - 58419737 58419753 8.0E-06 CTGTCAATAAAGTTGAT 17 V_SREBP1_Q5_M01173 TRANSFAC - 58419106 58419120 7.0E-06 TCCCTCACTCCATGT 15 V_AR_Q2_M00447 TRANSFAC + 58423099 58423113 7.0E-06 AAAGGGGTTTGTTCT 15 V_PAX4_04_M00380 TRANSFAC - 58421210 58421239 0.0E+00 AAAAATAAACAAAAATACACTCTTACTTCC 30 V_PAX4_04_M00380 TRANSFAC - 58421211 58421240 0.0E+00 AAAAAATAAACAAAAATACACTCTTACTTC 30 V_PAX2_02_M00486 TRANSFAC - 58420363 58420371 8.0E-06 AATAAACCC 9 V_T3RALPHA_Q6_M01724 TRANSFAC - 58421441 58421451 2.0E-06 CTTGAGGTCAA 11 V_IPF1_06_M01438 TRANSFAC - 58419182 58419197 6.0E-06 CTGGCAATTAGCACAC 16

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.