Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

LARS Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 51520 leucyl-tRNA synthetase chr5 - 145561794 - 145567294 145562294 Transcription Factor Binding Sites   Download all TFBS in the LARS promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints TBR1_TBX_DBD_monomeric_10_1 SELEX - 145562177 145562186 5.0E-06 AGGTGTGAAG 10 SOX21_HMG_DBD_dimeric_13_2 SELEX - 145562294 145562306 1.0E-06 GGAATTGTAGTCA 13 TFAP2B_TFAP_DBD_dimeric_11_1 SELEX + 145562748 145562758 4.0E-06 TGCCTCAGGCT 11 TFAP2B_TFAP_DBD_dimeric_11_1 SELEX - 145562748 145562758 1.0E-06 AGCCTGAGGCA 11 EWSR1-FLI1_MA0149.1 JASPAR - 145564876 145564893 3.0E-06 GAAAGTGAGGGAGGCAGC 18 PDX1_homeodomain_DBD_monomeric_8_1 SELEX - 145562518 145562525 5.0E-06 GTAATTAA 8 TFAP2A_TFAP_DBD_dimeric_11_1 SELEX + 145562748 145562758 2.0E-06 TGCCTCAGGCT 11 TFAP2A_TFAP_DBD_dimeric_11_1 SELEX - 145562748 145562758 3.0E-06 AGCCTGAGGCA 11 Creb5_bZIP_DBD_dimeric_12_1 SELEX + 145562365 145562376 4.0E-06 AGTGACGTCACT 12 Creb5_bZIP_DBD_dimeric_12_1 SELEX - 145562365 145562376 4.0E-06 AGTGACGTCACT 12 HOXA1_homeodomain_DBD_monomeric_10_1 SELEX - 145562517 145562526 1.0E-06 AGTAATTAAC 10 JDP2_bZIP_full_dimeric_12_1 SELEX + 145562365 145562376 9.0E-06 AGTGACGTCACT 12 JDP2_bZIP_full_dimeric_12_1 SELEX - 145562365 145562376 9.0E-06 AGTGACGTCACT 12 HOXB5_homeodomain_DBD_monomeric_10_1 SELEX - 145562517 145562526 7.0E-06 AGTAATTAAC 10 T_MA0009.1 JASPAR - 145562178 145562188 7.0E-06 GCAGGTGTGAA 11 Dlx2_homeodomain_DBD_monomeric_8_1 SELEX - 145562518 145562525 5.0E-06 GTAATTAA 8 SOX8_HMG_full_dimeric_13_1 SELEX - 145562295 145562307 5.0E-06 GGGAATTGTAGTC 13 Hoxa2_homeodomain_DBD_monomeric_10_1 SELEX - 145562517 145562526 2.0E-06 AGTAATTAAC 10 FOXJ3_forkhead_DBD_dimeric_14_1 SELEX + 145561866 145561879 8.0E-06 GTTAACAGACATCA 14 HOXB2_homeodomain_DBD_monomeric_10_1 SELEX - 145562517 145562526 1.0E-06 AGTAATTAAC 10 ATF7_bZIP_DBD_dimeric_14_1 SELEX + 145562364 145562377 4.0E-06 CAGTGACGTCACTG 14 ATF7_bZIP_DBD_dimeric_14_1 SELEX - 145562364 145562377 4.0E-06 CAGTGACGTCACTG 14 EMX1_homeodomain_DBD_monomeric_10_1 SELEX - 145562517 145562526 5.0E-06 AGTAATTAAC 10 HNF4A_nuclearreceptor_full_dimeric_16_1 SELEX + 145562386 145562401 2.0E-06 AACTACAAAGTCCATG 16 MEOX2_homeodomain_DBD_monomeric_10_1 SELEX - 145562517 145562526 1.0E-06 AGTAATTAAC 10 CREB3_bZIP_full_dimeric_14_1 SELEX + 145562364 145562377 3.0E-06 CAGTGACGTCACTG 14 CREB3_bZIP_full_dimeric_14_1 SELEX - 145562364 145562377 3.0E-06 CAGTGACGTCACTG 14 NFATC1_NFAT_full_dimeric_20_1 SELEX - 145561951 145561970 3.0E-06 AAGGGAAAGTCCTTTTCTAA 20 VAX1_homeodomain_DBD_monomeric_8_1 SELEX + 145562518 145562525 9.0E-06 TTAATTAC 8 TBX21_TBX_full_monomeric_10_1 SELEX - 145562178 145562187 6.0E-06 CAGGTGTGAA 10 Hoxd3_homeodomain_DBD_monomeric_10_1 SELEX - 145562517 145562526 1.0E-06 AGTAATTAAC 10 HOXB3_homeodomain_DBD_monomeric_10_1 SELEX - 145562517 145562526 2.0E-06 AGTAATTAAC 10 TFAP2C_TFAP_full_dimeric_11_1 SELEX + 145562748 145562758 2.0E-06 TGCCTCAGGCT 11 TFAP2C_TFAP_full_dimeric_11_1 SELEX - 145562748 145562758 1.0E-06 AGCCTGAGGCA 11 VAX2_homeodomain_DBD_monomeric_8_1 SELEX + 145562518 145562525 5.0E-06 TTAATTAC 8 MEOX1_homeodomain_full_monomeric_10_1 SELEX - 145562517 145562526 1.0E-06 AGTAATTAAC 10 Sox3_HMG_DBD_dimeric_17_3 SELEX - 145562292 145562308 8.0E-06 TGGGAATTGTAGTCAGT 17 VDR_nuclearreceptor_full_dimeric_16_1 SELEX - 145562092 145562107 5.0E-06 GAGGTCGCCAGGGTCA 16 MNX1_homeodomain_DBD_monomeric_10_1 SELEX - 145562517 145562526 6.0E-06 AGTAATTAAC 10 Tcfap2a_TFAP_DBD_dimeric_11_1 SELEX + 145562748 145562758 3.0E-06 TGCCTCAGGCT 11 Tcfap2a_TFAP_DBD_dimeric_11_1 SELEX - 145562748 145562758 2.0E-06 AGCCTGAGGCA 11 Meox2_homeodomain_DBD_monomeric_8_1 SELEX + 145562518 145562525 9.0E-06 TTAATTAC 8 FOXJ2_forkhead_DBD_dimeric_14_1 SELEX + 145561866 145561879 8.0E-06 GTTAACAGACATCA 14 V_FOXP3_Q4_M00992 TRANSFAC - 145564949 145564965 5.0E-06 GAGCATTTAACTCAGAC 17 V_TCF3_01_M01594 TRANSFAC + 145562641 145562653 5.0E-06 CCTTTTTTTTTTT 13 V_NFKB_Q6_01_M00774 TRANSFAC - 145561957 145561972 6.0E-06 TGAAGGGAAAGTCCTT 16 V_FLI1_Q6_M01208 TRANSFAC - 145564929 145564939 0.0E+00 CAGGAAGTGAT 11 V_EVI1_05_M00082 TRANSFAC + 145561839 145561849 7.0E-06 AAATATGATAT 11 V_SIX6_02_M01398 TRANSFAC - 145561839 145561855 2.0E-06 ACTTGGATATCATATTT 17 V_CREB_Q4_01_M00917 TRANSFAC + 145562364 145562374 7.0E-06 CAGTGACGTCA 11 V_CREB_Q4_01_M00917 TRANSFAC - 145562367 145562377 7.0E-06 CAGTGACGTCA 11 V_MEF2_02_M00231 TRANSFAC - 145562539 145562560 9.0E-06 TGGCAAGCCATAAGTAGCACCT 22 V_TBR2_01_M01774 TRANSFAC - 145562178 145562186 3.0E-06 AGGTGTGAA 9 V_HNF4_Q6_M00967 TRANSFAC + 145562392 145562400 7.0E-06 AAAGTCCAT 9 V_HOXA4_01_M01370 TRANSFAC - 145562514 145562530 5.0E-06 GTATAGTAATTAACTGC 17 V_HOXD1_01_M01448 TRANSFAC - 145562513 145562529 1.0E-06 TATAGTAATTAACTGCG 17 V_P50RELAP65_Q5_01_M01224 TRANSFAC + 145561959 145561970 7.0E-06 GGACTTTCCCTT 12 V_JUNDM2_03_M02772 TRANSFAC + 145562363 145562378 9.0E-06 GCAGTGACGTCACTGG 16 V_JUNDM2_03_M02772 TRANSFAC - 145562363 145562378 5.0E-06 CCAGTGACGTCACTGC 16 V_HOXC6_01_M01406 TRANSFAC - 145562513 145562529 1.0E-06 TATAGTAATTAACTGCG 17 V_HOXC6_01_M01406 TRANSFAC + 145562514 145562530 6.0E-06 GCAGTTAATTACTATAC 17 V_LHX3_01_M01471 TRANSFAC + 145562514 145562530 8.0E-06 GCAGTTAATTACTATAC 17 V_LHX3A_01_M00510 TRANSFAC + 145562516 145562525 7.0E-06 AGTTAATTAC 10 V_GM497_04_M02864 TRANSFAC + 145562166 145562181 8.0E-06 TAAAGCACACGCTTCA 16 V_TCFAP2E_04_M02926 TRANSFAC - 145562572 145562585 6.0E-06 GACAGTAAAAAATA 14 V_TCFAP2E_04_M02926 TRANSFAC - 145562642 145562655 9.0E-06 CAAAAAAAAAAAAG 14 V_TCFAP2E_04_M02926 TRANSFAC - 145562643 145562656 3.0E-06 TCAAAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC - 145562644 145562657 2.0E-06 CTCAAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC - 145562646 145562659 2.0E-06 GTCTCAAAAAAAAA 14 V_NKX62_Q2_M00489 TRANSFAC - 145562517 145562528 9.0E-06 ATAGTAATTAAC 12 V_BARBIE_01_M00238 TRANSFAC - 145562635 145562649 7.0E-06 AAAAAAAGGAGATTG 15 V_HNF1_C_M00206 TRANSFAC - 145562609 145562625 8.0E-06 GGTTATACAATGTCTAA 17 V_PPARGRXRA_01_M02262 TRANSFAC - 145562121 145562135 8.0E-06 GGAGGGGAAAGGTAA 15 V_AP1_Q6_M00174 TRANSFAC - 145564921 145564931 5.0E-06 GATGACTAAAT 11 V_ETS_Q4_M00771 TRANSFAC + 145564928 145564939 2.0E-06 CATCACTTCCTG 12 V_ELF4_04_M02850 TRANSFAC - 145562642 145562658 1.0E-06 TCTCAAAAAAAAAAAAG 17 V_ELF4_04_M02850 TRANSFAC - 145562643 145562659 1.0E-06 GTCTCAAAAAAAAAAAA 17 V_FOXA2_02_M02853 TRANSFAC + 145561830 145561844 0.0E+00 AGAAATAACAAATAT 15 V_HOXA6_01_M01392 TRANSFAC + 145562515 145562530 1.0E-06 CAGTTAATTACTATAC 16 V_RFXDC2_04_M02894 TRANSFAC - 145561841 145561857 9.0E-06 GTACTTGGATATCATAT 17 V_LMX1_01_M01409 TRANSFAC + 145562514 145562530 8.0E-06 GCAGTTAATTACTATAC 17 V_ZFP105_03_M02827 TRANSFAC - 145562640 145562654 1.0E-06 AAAAAAAAAAAAGGA 15 V_ZFP105_03_M02827 TRANSFAC - 145562641 145562655 7.0E-06 CAAAAAAAAAAAAGG 15 V_ZFP105_03_M02827 TRANSFAC - 145562642 145562656 3.0E-06 TCAAAAAAAAAAAAG 15 V_ZFP105_03_M02827 TRANSFAC - 145562643 145562657 1.0E-06 CTCAAAAAAAAAAAA 15 V_SIX1_01_M01313 TRANSFAC - 145561839 145561855 1.0E-06 ACTTGGATATCATATTT 17 V_SOX1_04_M02906 TRANSFAC - 145561832 145561846 2.0E-06 TCATATTTGTTATTT 15 V_HOXA3_02_M01337 TRANSFAC - 145562517 145562530 7.0E-06 GTATAGTAATTAAC 14 V_SIX3_01_M01358 TRANSFAC - 145561839 145561855 3.0E-06 ACTTGGATATCATATTT 17 V_ARID3A_02_M02839 TRANSFAC - 145561839 145561853 0.0E+00 TTGGATATCATATTT 15 V_HOXA1_01_M01487 TRANSFAC + 145562513 145562528 9.0E-06 CGCAGTTAATTACTAT 16 V_HOXA1_01_M01487 TRANSFAC - 145562515 145562530 6.0E-06 GTATAGTAATTAACTG 16 V_HNF3ALPHA_Q6_M00724 TRANSFAC - 145561833 145561843 5.0E-06 TATTTGTTATT 11 V_CREBATF_Q6_M00981 TRANSFAC + 145562366 145562374 9.0E-06 GTGACGTCA 9 V_CREBATF_Q6_M00981 TRANSFAC - 145562367 145562375 9.0E-06 GTGACGTCA 9 V_TEL2_Q6_M00678 TRANSFAC + 145564930 145564939 4.0E-06 TCACTTCCTG 10 V_PROP1_02_M01320 TRANSFAC + 145562514 145562530 1.0E-05 GCAGTTAATTACTATAC 17 V_CREB_Q2_01_M00916 TRANSFAC - 145562363 145562376 6.0E-06 AGTGACGTCACTGC 14 V_CREB_Q2_01_M00916 TRANSFAC + 145562365 145562378 6.0E-06 AGTGACGTCACTGG 14 V_IK3_01_M00088 TRANSFAC - 145564973 145564985 9.0E-06 TTCAGGGAACATC 13 V_SIX2_01_M01433 TRANSFAC - 145561839 145561855 2.0E-06 ACTTGGATATCATATTT 17 V_MZF1_02_M00084 TRANSFAC - 145562126 145562138 8.0E-06 GAGGGAGGGGAAA 13 V_HNF4A_02_M02868 TRANSFAC + 145562388 145562403 6.0E-06 CTACAAAGTCCATGAT 16 V_MAF_Q6_01_M00983 TRANSFAC + 145562186 145562196 9.0E-06 TGCTGAGGCAA 11 V_HOXB4_01_M01424 TRANSFAC + 145562514 145562530 9.0E-06 GCAGTTAATTACTATAC 17 V_TFIII_Q6_M00706 TRANSFAC - 145562131 145562139 6.0E-06 AGAGGGAGG 9 V_CREM_Q6_M01820 TRANSFAC - 145562364 145562374 3.0E-06 TGACGTCACTG 11 V_CREM_Q6_M01820 TRANSFAC + 145562367 145562377 3.0E-06 TGACGTCACTG 11 V_HOXA7_02_M01336 TRANSFAC + 145562514 145562530 0.0E+00 GCAGTTAATTACTATAC 17 V_VJUN_01_M00036 TRANSFAC - 145562363 145562378 2.0E-06 CCAGTGACGTCACTGC 16 V_MTF1_06_M02882 TRANSFAC + 145561832 145561845 1.0E-06 AAATAACAAATATG 14 V_MTF1_06_M02882 TRANSFAC - 145562641 145562654 6.0E-06 AAAAAAAAAAAAGG 14 V_CREBP1_Q2_M00179 TRANSFAC - 145562365 145562376 0.0E+00 AGTGACGTCACT 12 V_FAC1_01_M00456 TRANSFAC + 145561830 145561843 7.0E-06 AGAAATAACAAATA 14 V_HNF1_01_M00132 TRANSFAC + 145562516 145562530 6.0E-06 AGTTAATTACTATAC 15 V_SP4_04_M02914 TRANSFAC - 145561923 145561937 1.0E-06 TTAAGGCGTGCCTTT 15 V_BARHL1_01_M01332 TRANSFAC + 145564914 145564929 7.0E-06 ACCAACCATTTAGTCA 16 V_NKX3A_02_M01383 TRANSFAC - 145561847 145561863 7.0E-06 TACGGAGTACTTGGATA 17 V_ATF1_03_M02738 TRANSFAC + 145562363 145562378 2.0E-06 GCAGTGACGTCACTGG 16 V_ATF1_03_M02738 TRANSFAC - 145562363 145562378 5.0E-06 CCAGTGACGTCACTGC 16 V_IPF1_01_M01233 TRANSFAC + 145562516 145562525 1.0E-05 AGTTAATTAC 10 V_MSX1_02_M01412 TRANSFAC + 145562513 145562528 5.0E-06 CGCAGTTAATTACTAT 16 V_NRSF_01_M00256 TRANSFAC - 145562528 145562548 8.0E-06 AGTAGCACCTCAGTCACCGTA 21 V_BARX2_01_M01431 TRANSFAC - 145562513 145562528 4.0E-06 ATAGTAATTAACTGCG 16 V_TBX5_Q5_M01044 TRANSFAC + 145562178 145562187 5.0E-06 TTCACACCTG 10 V_LEF1TCF1_Q4_M00978 TRANSFAC - 145562386 145562396 5.0E-06 ACTTTGTAGTT 11 V_SRF_06_M02916 TRANSFAC - 145562639 145562655 2.0E-06 CAAAAAAAAAAAAGGAG 17 V_SRF_06_M02916 TRANSFAC - 145562640 145562656 1.0E-06 TCAAAAAAAAAAAAGGA 17 V_SRF_06_M02916 TRANSFAC - 145562641 145562657 3.0E-06 CTCAAAAAAAAAAAAGG 17 V_SRF_06_M02916 TRANSFAC - 145562642 145562658 2.0E-06 TCTCAAAAAAAAAAAAG 17 V_SRF_06_M02916 TRANSFAC - 145562643 145562659 2.0E-06 GTCTCAAAAAAAAAAAA 17 V_VAX1_01_M01397 TRANSFAC + 145562515 145562530 6.0E-06 CAGTTAATTACTATAC 16 V_EWSR1FLI1_01_M02252 TRANSFAC - 145564876 145564893 3.0E-06 GAAAGTGAGGGAGGCAGC 18 V_SIX6_01_M01345 TRANSFAC - 145561839 145561855 1.0E-06 ACTTGGATATCATATTT 17 V_VDR_Q3_M00444 TRANSFAC - 145562464 145562478 1.0E-06 GGGTGAAAAGGTTGA 15 V_ALX3_01_M01355 TRANSFAC - 145562513 145562529 4.0E-06 TATAGTAATTAACTGCG 17 V_DR3_Q4_M00966 TRANSFAC + 145562462 145562482 7.0E-06 CATCAACCTTTTCACCCGGTA 21 V_DLX1_01_M01439 TRANSFAC - 145562517 145562530 4.0E-06 GTATAGTAATTAAC 14 V_BARX1_01_M01340 TRANSFAC + 145562515 145562530 9.0E-06 CAGTTAATTACTATAC 16 V_ATF_B_M00338 TRANSFAC - 145562364 145562375 4.0E-06 GTGACGTCACTG 12 V_ATF_B_M00338 TRANSFAC + 145562366 145562377 4.0E-06 GTGACGTCACTG 12 V_ALX3_02_M02943 TRANSFAC - 145562513 145562529 4.0E-06 TATAGTAATTAACTGCG 17 V_TCF3_05_M02920 TRANSFAC - 145562644 145562658 4.0E-06 TCTCAAAAAAAAAAA 15 V_HOXB5_01_M01319 TRANSFAC + 145562515 145562530 3.0E-06 CAGTTAATTACTATAC 16 PPARG_RXRA_MA0065.2 JASPAR - 145562121 145562135 8.0E-06 GGAGGGGAAAGGTAA 15 V_HOX13_02_M01452 TRANSFAC + 145562515 145562530 7.0E-06 CAGTTAATTACTATAC 16 V_HOXC8_01_M01321 TRANSFAC - 145562515 145562530 2.0E-06 GTATAGTAATTAACTG 16 V_IPF1_06_M01438 TRANSFAC + 145562515 145562530 3.0E-06 CAGTTAATTACTATAC 16

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.