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PCSK2 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 5126 proprotein convertase subtilisin/kexin type 2 chr20 + 17201751 - 17208096 17207596 Transcription Factor Binding Sites   Download all TFBS in the PCSK2 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints NF-kappaB_MA0061.1 JASPAR + 17207365 17207374 7.0E-06 GGGATTTTCC 10 EBF1_EBF_full_dimeric_14_1 SELEX + 17207615 17207628 1.0E-06 AGCCCCTAGGGAAT 14 EBF1_EBF_full_dimeric_14_1 SELEX - 17207615 17207628 2.0E-06 ATTCCCTAGGGGCT 14 NFYA_MA0060.1 JASPAR - 17207563 17207578 7.0E-06 AGCGGCCAATGAGGGC 16 Creb5_bZIP_DBD_dimeric_12_1 SELEX + 17207324 17207335 4.0E-06 AATGACATCACT 12 JDP2_bZIP_full_dimeric_12_1 SELEX + 17207324 17207335 9.0E-06 AATGACATCACT 12 POU3F3_POU_DBD_monomeric_13_1 SELEX + 17207648 17207660 7.0E-06 AAAATGCAGATTT 13 SP1_MA0079.2 JASPAR + 17210054 17210063 3.0E-06 CCCCTCCCCC 10 Mafb_bZIP_DBD_dimeric_17_1 SELEX + 17207650 17207666 9.0E-06 AATGCAGATTTAGCATC 17 Mafb_bZIP_DBD_dimeric_17_1 SELEX - 17207650 17207666 6.0E-06 GATGCTAAATCTGCATT 17 MAFK_bZIP_full_dimeric_15_1 SELEX + 17207651 17207665 3.0E-06 ATGCAGATTTAGCAT 15 MAFK_bZIP_full_dimeric_15_1 SELEX - 17207651 17207665 2.0E-06 ATGCTAAATCTGCAT 15 MAFK_bZIP_DBD_dimeric_21_1 SELEX + 17207648 17207668 1.0E-06 AAAATGCAGATTTAGCATCAA 21 MAFK_bZIP_DBD_dimeric_21_1 SELEX - 17207648 17207668 0.0E+00 TTGATGCTAAATCTGCATTTT 21 SCRT1_C2H2_DBD_monomeric_15_1 SELEX - 17210035 17210049 7.0E-06 GAGCCACAGGTTTCT 15 ZSCAN4_C2H2_full_monomeric_15_1 SELEX + 17207277 17207291 5.0E-06 GGCACACACCGTAAT 15 MAFG_bZIP_full_dimeric_21_1 SELEX + 17207648 17207668 1.0E-06 AAAATGCAGATTTAGCATCAA 21 MAFG_bZIP_full_dimeric_21_1 SELEX - 17207648 17207668 2.0E-06 TTGATGCTAAATCTGCATTTT 21 REST_MA0138.2 JASPAR - 17208409 17208429 2.0E-06 CTTGGTACCTCGGACAGCATC 21 V_MINI20_B_M00324 TRANSFAC + 17207323 17207343 1.0E-05 CAATGACATCACTCCGCCGCC 21 V_MEQ_01_M02049 TRANSFAC + 17207784 17207792 7.0E-06 AACACACAC 9 V_FOXP1_01_M00987 TRANSFAC - 17209632 17209651 8.0E-06 TTTATTGTGTTGGTGTCTCT 20 V_NFKAPPAB65_01_M00052 TRANSFAC + 17207365 17207374 7.0E-06 GGGATTTTCC 10 V_NFKB_C_M00208 TRANSFAC + 17207364 17207375 3.0E-06 GGGGATTTTCCT 12 V_NFKB_Q6_01_M00774 TRANSFAC - 17207364 17207379 6.0E-06 GCCCAGGAAAATCCCC 16 V_MAFK_03_M02776 TRANSFAC + 17207646 17207660 2.0E-06 TGAAAATGCAGATTT 15 V_BCL6_01_M01183 TRANSFAC - 17207838 17207853 0.0E+00 TTTTAAAAAAATCTTT 16 V_BCL6_01_M01183 TRANSFAC - 17207839 17207854 4.0E-06 TTTTTAAAAAAATCTT 16 V_COE1_Q6_M01871 TRANSFAC + 17207617 17207630 1.0E-06 CCCCTAGGGAATTG 14 V_RELBP52_01_M01239 TRANSFAC + 17207364 17207373 6.0E-06 GGGGATTTTC 10 V_P50P50_Q3_M01223 TRANSFAC + 17207363 17207375 1.0E-05 GGGGGATTTTCCT 13 V_EAR2_Q2_M01728 TRANSFAC + 17208349 17208362 3.0E-06 TGCTCTTTGACTTG 14 V_SP1_03_M02281 TRANSFAC + 17210054 17210063 3.0E-06 CCCCTCCCCC 10 V_SP1_02_M01303 TRANSFAC + 17207425 17207435 8.0E-06 GGGGCGGGGGC 11 V_BARBIE_01_M00238 TRANSFAC - 17210061 17210075 7.0E-06 ATGAAAAGGTGTGGG 15 V_NRSE_B_M00325 TRANSFAC - 17208409 17208429 2.0E-06 CTTGGTACCTCGGACAGCATC 21 V_WT1_Q6_01_M02036 TRANSFAC - 17207514 17207523 4.0E-06 CGCCCCCGCC 10 V_ELF4_04_M02850 TRANSFAC - 17207838 17207854 0.0E+00 TTTTTAAAAAAATCTTT 17 V_ELF4_04_M02850 TRANSFAC - 17207839 17207855 1.0E-06 GTTTTTAAAAAAATCTT 17 V_GC_01_M00255 TRANSFAC + 17207423 17207436 9.0E-06 AAGGGGCGGGGGCG 14 V_LMX1_01_M01409 TRANSFAC + 17207840 17207856 6.0E-06 AGATTTTTTTAAAAACT 17 V_FKLF_Q5_M01837 TRANSFAC + 17207508 17207517 5.0E-06 GGGGTGGGCG 10 V_KROX_Q6_M00982 TRANSFAC - 17207425 17207438 0.0E+00 CGCGCCCCCGCCCC 14 V_KROX_Q6_M00982 TRANSFAC - 17207512 17207525 1.0E-06 CCCGCCCCCGCCCA 14 V_ZBP89_Q4_M01816 TRANSFAC + 17210055 17210064 4.0E-06 CCCTCCCCCA 10 V_OLF1_01_M00261 TRANSFAC - 17207611 17207632 1.0E-06 TCCAATTCCCTAGGGGCTGGGG 22 V_NFKB_Q6_M00194 TRANSFAC + 17207363 17207376 3.0E-06 GGGGGATTTTCCTG 14 V_SP1_Q6_M00196 TRANSFAC + 17207423 17207435 6.0E-06 AAGGGGCGGGGGC 13 V_EGR1_Q6_M01873 TRANSFAC + 17207515 17207524 4.0E-06 GCGGGGGCGG 10 V_REST_01_M01256 TRANSFAC + 17208405 17208426 2.0E-06 CGGGGATGCTGTCCGAGGTACC 22 V_ATF1_Q6_01_M01861 TRANSFAC + 17207586 17207594 4.0E-06 TCACGTCAC 9 V_NCX_02_M01420 TRANSFAC + 17207841 17207857 4.0E-06 GATTTTTTTAAAAACTA 17 V_TBP_06_M02814 TRANSFAC - 17207841 17207856 9.0E-06 AGTTTTTAAAAAAATC 16 V_TBP_06_M02814 TRANSFAC + 17207842 17207857 4.0E-06 ATTTTTTTAAAAACTA 16 V_VJUN_01_M00036 TRANSFAC + 17207322 17207337 1.0E-05 ACAATGACATCACTCC 16 V_MTF1_06_M02882 TRANSFAC - 17207843 17207856 7.0E-06 AGTTTTTAAAAAAA 14 V_TCF7_04_M02921 TRANSFAC - 17207842 17207856 4.0E-06 AGTTTTTAAAAAAAT 15 V_TCF7_04_M02921 TRANSFAC + 17207843 17207857 3.0E-06 TTTTTTTAAAAACTA 15 V_NFY_01_M00287 TRANSFAC - 17207563 17207578 5.0E-06 AGCGGCCAATGAGGGC 16 V_NRSF_01_M00256 TRANSFAC + 17207658 17207678 6.0E-06 TTTAGCATCAAGCACAGACCT 21 V_NRSF_01_M00256 TRANSFAC - 17208409 17208429 2.0E-06 CTTGGTACCTCGGACAGCATC 21 V_REST_02_M02256 TRANSFAC - 17208409 17208429 2.0E-06 CTTGGTACCTCGGACAGCATC 21 V_ZFP281_01_M01597 TRANSFAC - 17210054 17210064 1.0E-06 TGGGGGAGGGG 11 V_NFKAPPAB_01_M00054 TRANSFAC + 17207365 17207374 8.0E-06 GGGATTTTCC 10 V_ZFP281_04_M02831 TRANSFAC + 17210052 17210066 1.0E-06 TCCCCCTCCCCCACA 15 V_SRF_06_M02916 TRANSFAC - 17207838 17207854 1.0E-06 TTTTTAAAAAAATCTTT 17 V_SRF_06_M02916 TRANSFAC - 17207839 17207855 6.0E-06 GTTTTTAAAAAAATCTT 17 V_VMAF_01_M00035 TRANSFAC + 17207649 17207667 3.0E-06 AAATGCAGATTTAGCATCA 19 V_HOMEZ_01_M01429 TRANSFAC - 17207847 17207863 3.0E-06 TATATATAGTTTTTAAA 17 V_MEF2_01_M00006 TRANSFAC - 17207838 17207853 2.0E-06 TTTTAAAAAAATCTTT 16 V_SP1_Q2_01_M00933 TRANSFAC - 17207424 17207433 7.0E-06 CCCCGCCCCT 10 V_UF1H3BETA_Q6_M01068 TRANSFAC - 17210053 17210066 2.0E-06 TGTGGGGGAGGGGG 14 V_NFYA_Q5_M02106 TRANSFAC - 17207563 17207576 1.0E-06 CGGCCAATGAGGGC 14 V_SP1_Q4_01_M00932 TRANSFAC + 17207423 17207435 5.0E-06 AAGGGGCGGGGGC 13

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