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PCSK6 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 5046 proprotein convertase subtilisin/kexin type 6 chr15 - 102029687 - 102035187 102030187 Transcription Factor Binding Sites   Download all TFBS in the PCSK6 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints HOXD12_homeodomain_DBD_monomeric_9_1 SELEX + 102032392 102032400 1.0E-06 GTAATAAAA 9 Hoxc10_homeodomain_DBD_monomeric_10_2 SELEX + 102032392 102032401 2.0E-06 GTAATAAAAC 10 Hoxd9_homeodomain_DBD_monomeric_10_1 SELEX + 102032392 102032401 9.0E-06 GTAATAAAAC 10 POU2F1_POU_DBD_dimeric_14_1 SELEX - 102032149 102032162 1.0E-05 AATAAAAATTCAGA 14 RFX4_RFX_DBD_dimeric_16_1 SELEX + 102032083 102032098 9.0E-06 TGTTTCCATAATAATG 16 RFX4_RFX_DBD_dimeric_16_1 SELEX - 102032083 102032098 6.0E-06 CATTATTATGGAAACA 16 HINFP1_C2H2_full_dimeric_20_1 SELEX - 102029604 102029623 9.0E-06 GCGGACCGCGTGGCGGCGGC 20 CEBPA_MA0102.2 JASPAR + 102033282 102033290 4.0E-06 TTTTGCAAT 9 SOX8_HMG_full_dimeric_17_1 SELEX + 102032046 102032062 9.0E-06 CCGCAACGGCAGTGATT 17 NR2F1_MA0017.1 JASPAR - 102028840 102028853 7.0E-06 TGACCTTTGGCAAG 14 HOXD11_homeodomain_DBD_monomeric_10_2 SELEX + 102032391 102032400 1.0E-06 TGTAATAAAA 10 Rfx3_RFX_DBD_dimeric_16_1 SELEX + 102032083 102032098 4.0E-06 TGTTTCCATAATAATG 16 HOXC12_homeodomain_DBD_monomeric_9_1 SELEX + 102032392 102032400 1.0E-06 GTAATAAAA 9 HOXD13_homeodomain_DBD_monomeric_10_1 SELEX + 102032392 102032401 5.0E-06 GTAATAAAAC 10 HOXC11_homeodomain_full_monomeric_11_2 SELEX + 102032391 102032401 4.0E-06 TGTAATAAAAC 11 Ascl2_bHLH_DBD_dimeric_10_1 SELEX - 102032017 102032026 9.0E-06 ACCAGCTGCT 10 Gfi_MA0038.1 JASPAR - 102032055 102032064 3.0E-06 AAAATCACTG 10 Gata1_MA0035.2 JASPAR + 102032072 102032082 6.0E-06 AGAGATAAGGG 11 HOXA13_homeodomain_full_monomeric_10_1 SELEX + 102032392 102032401 1.0E-05 GTAATAAAAC 10 RFX2_RFX_DBD_dimeric_16_1 SELEX + 102032083 102032098 4.0E-06 TGTTTCCATAATAATG 16 RFX2_RFX_DBD_dimeric_16_1 SELEX - 102032083 102032098 5.0E-06 CATTATTATGGAAACA 16 Foxd3_MA0041.1 JASPAR + 102032152 102032163 6.0E-06 GAATTTTTATTT 12 ZNF282_C2H2_DBD_monomeric_17_1 SELEX + 102028776 102028792 6.0E-06 CTTTCCGACAACCCAGC 17 Pou5f1_MA0142.1 JASPAR - 102032084 102032098 2.0E-06 CATTATTATGGAAAC 15 Myf_MA0055.1 JASPAR + 102029709 102029720 4.0E-06 CAGCAGCAGCAG 12 Myf_MA0055.1 JASPAR + 102032016 102032027 1.0E-06 AAGCAGCTGGTG 12 HOXC13_homeodomain_DBD_monomeric_10_1 SELEX - 102032155 102032164 9.0E-06 CAAATAAAAA 10 HOXC13_homeodomain_DBD_monomeric_10_1 SELEX + 102032392 102032401 8.0E-06 GTAATAAAAC 10 CPEB1_RRM_full_monomeric_8_1 SELEX - 102032155 102032162 4.0E-06 AATAAAAA 8 Hoxa11_homeodomain_DBD_monomeric_11_1 SELEX + 102032391 102032401 7.0E-06 TGTAATAAAAC 11 Sox2_MA0143.1 JASPAR - 102032085 102032099 7.0E-06 ACATTATTATGGAAA 15 CDX2_homeodomain_DBD_monomeric_9_1 SELEX + 102032392 102032400 1.0E-06 GTAATAAAA 9 Foxj3_forkhead_DBD_dimeric_13_1 SELEX + 102027156 102027168 4.0E-06 GTGAACACAAACA 13 CDX1_homeodomain_DBD_monomeric_9_1 SELEX + 102032392 102032400 1.0E-06 GTAATAAAA 9 HOXA10_homeodomain_DBD_monomeric_11_1 SELEX + 102032391 102032401 1.0E-06 TGTAATAAAAC 11 HOXA10_homeodomain_DBD_monomeric_11_1 SELEX - 102032427 102032437 8.0E-06 AGTAATAAATC 11 V_SOX40_04_M02908 TRANSFAC + 102032006 102032021 5.0E-06 AATGATTATAAAGCAG 16 V_GATA2_02_M00348 TRANSFAC + 102032072 102032081 7.0E-06 AGAGATAAGG 10 V_CEBP_Q3_M00770 TRANSFAC + 102033279 102033290 7.0E-06 GTGTTTTGCAAT 12 V_HMGIY_Q3_M01010 TRANSFAC + 102032175 102032189 6.0E-06 AATGTATTTTACTAA 15 V_FOXD3_01_M00130 TRANSFAC + 102032152 102032163 5.0E-06 GAATTTTTATTT 12 V_GM397_03_M02760 TRANSFAC - 102031986 102032002 8.0E-06 CTGATGTGCAGTTACAT 17 V_GATA3_03_M00351 TRANSFAC - 102028770 102028779 1.0E-06 AAAGATCTAA 10 V_POU5F1_02_M02245 TRANSFAC - 102032084 102032098 2.0E-06 CATTATTATGGAAAC 15 V_HOXA13_02_M01297 TRANSFAC - 102032155 102032163 4.0E-06 AAATAAAAA 9 V_NR2F2_03_M02783 TRANSFAC + 102028842 102028857 7.0E-06 TGCCAAAGGTCACACC 16 V_ISL2_01_M01328 TRANSFAC - 102032103 102032118 8.0E-06 CTGAATCCCTTAATCT 16 V_AP2_Q6_M00189 TRANSFAC - 102029912 102029923 6.0E-06 CACCCCCCGGCG 12 V_PITX2_Q6_M02114 TRANSFAC + 102028924 102028933 5.0E-06 TTTAAACCCA 10 V_PPAR_DR1_Q2_M00763 TRANSFAC - 102028841 102028853 4.0E-06 TGACCTTTGGCAA 13 V_SP1_02_M01303 TRANSFAC + 102034913 102034923 5.0E-06 GGGGTGGGGGG 11 V_SP1_02_M01303 TRANSFAC + 102034938 102034948 5.0E-06 GGGGTGGGGAG 11 V_AP4_Q6_01_M00927 TRANSFAC - 102032018 102032026 6.0E-06 ACCAGCTGC 9 V_CEBPB_01_M00109 TRANSFAC + 102033279 102033292 8.0E-06 GTGTTTTGCAATCA 14 V_TAL1_GATA1_01_M02243 TRANSFAC + 102032063 102032080 5.0E-06 TTGACAGGCAGAGATAAG 18 V_WT1_Q6_01_M02036 TRANSFAC - 102029679 102029688 4.0E-06 CGCCCCCGCC 10 V_RPC155_01_M01798 TRANSFAC - 102028921 102028936 0.0E+00 TCCTGGGTTTAAAACC 16 V_ELF4_04_M02850 TRANSFAC - 102032152 102032168 0.0E+00 TCTCCAAATAAAAATTC 17 V_MYF_01_M01302 TRANSFAC + 102029709 102029720 4.0E-06 CAGCAGCAGCAG 12 V_MYF_01_M01302 TRANSFAC + 102032016 102032027 1.0E-06 AAGCAGCTGGTG 12 V_OCT1_03_M00137 TRANSFAC - 102032005 102032017 3.0E-06 TTTATAATCATTT 13 V_HOXB13_01_M01467 TRANSFAC - 102032152 102032167 7.0E-06 CTCCAAATAAAAATTC 16 V_GFI1_01_M00250 TRANSFAC - 102032047 102032070 4.0E-06 CCTGTCAAAATCACTGCCGTTGCG 24 V_GATA3_05_M02859 TRANSFAC - 102032376 102032397 3.0E-06 TATTACAGATCCTATCACAATG 22 V_COUP_01_M00158 TRANSFAC - 102028840 102028853 7.0E-06 TGACCTTTGGCAAG 14 V_POLY_C_M00212 TRANSFAC - 102032418 102032435 0.0E+00 TAATAAATCCCCTCCCTG 18 V_PAX9_B_M00329 TRANSFAC - 102028755 102028778 5.0E-06 AAGATCTAATGCTGCGTTGCCACA 24 V_KROX_Q6_M00982 TRANSFAC - 102029677 102029690 1.0E-06 TCCGCCCCCGCCGC 14 V_CEBPB_02_M00117 TRANSFAC - 102033279 102033292 5.0E-06 TGATTGCAAAACAC 14 V_CDX2_01_M01449 TRANSFAC + 102032388 102032403 1.0E-06 ATCTGTAATAAAACTT 16 V_MAZ_Q6_01_M02023 TRANSFAC + 102034937 102034950 0.0E+00 GGGGGTGGGGAGGG 14 V_AP2BETA_Q3_M01858 TRANSFAC + 102028689 102028704 1.0E-06 GCCGAGGGCTGCGGGG 16 V_AP2BETA_Q3_M01858 TRANSFAC - 102028936 102028951 8.0E-06 GCGCAGGGCCGGGGGT 16 V_EGR1_Q6_M01873 TRANSFAC + 102029680 102029689 4.0E-06 GCGGGGGCGG 10 V_CDX2_Q5_M00729 TRANSFAC - 102032391 102032404 0.0E+00 CAAGTTTTATTACA 14 V_MATH1_Q2_M01716 TRANSFAC + 102032018 102032027 3.0E-06 GCAGCTGGTG 10 V_HOX13_01_M00023 TRANSFAC - 102032081 102032110 3.0E-06 CTTAATCTACCACATTATTATGGAAACACC 30 V_CDX1_01_M01373 TRANSFAC + 102032388 102032403 1.0E-06 ATCTGTAATAAAACTT 16 V_OCT1_04_M00138 TRANSFAC - 102032141 102032163 3.0E-06 AAATAAAAATTCAGATGCATTTT 23 Tal1_Gata1_MA0140.1 JASPAR + 102032063 102032080 5.0E-06 TTGACAGGCAGAGATAAG 18 V_GATA1_09_M02254 TRANSFAC + 102032072 102032082 6.0E-06 AGAGATAAGGG 11 V_SMAD4_Q6_M00733 TRANSFAC + 102032110 102032124 6.0E-06 GGGATTCAGCCTGCT 15 V_OCT4_02_M01124 TRANSFAC + 102032221 102032235 4.0E-06 TTTGTCATGGAAGTG 15 V_FOXM1_01_M00630 TRANSFAC + 102033309 102033317 7.0E-06 AAATTGAGT 9 V_GFI1_Q6_M01067 TRANSFAC - 102032053 102032065 0.0E+00 CAAAATCACTGCC 13 V_T3R_01_M00239 TRANSFAC - 102033397 102033412 9.0E-06 CACTGGGGTCACACCA 16 V_TAL1_01_M01591 TRANSFAC - 102032072 102032084 4.0E-06 CACCCTTATCTCT 13 V_HEN1_02_M00058 TRANSFAC - 102032011 102032032 5.0E-06 GGAGGCACCAGCTGCTTTATAA 22 V_EBNA1_01_M01745 TRANSFAC + 102031881 102031896 1.0E-06 GGCAGCATGTGTTACC 16 V_EBNA1_01_M01745 TRANSFAC - 102031881 102031896 3.0E-06 GGTAACACATGCTGCC 16 V_CBF_01_M01079 TRANSFAC + 102032092 102032107 7.0E-06 AATAATGTGGTAGATT 16 V_GFI1B_01_M01058 TRANSFAC - 102032053 102032064 9.0E-06 AAAATCACTGCC 12 V_BDP1_01_M01796 TRANSFAC + 102028921 102028932 7.0E-06 GGTTTTAAACCC 12 V_DOBOX5_01_M01463 TRANSFAC + 102032421 102032437 3.0E-06 GGAGGGGATTTATTACT 17 V_OTX2_01_M01387 TRANSFAC + 102032421 102032437 6.0E-06 GGAGGGGATTTATTACT 17 V_TBX15_02_M01264 TRANSFAC - 102033235 102033252 3.0E-06 GGATGTTAAGATGTGAGA 18 V_PLZF_02_M01075 TRANSFAC + 102032139 102032167 6.0E-06 CTAAAATGCATCTGAATTTTTATTTGGAG 29 V_CEBPB_Q6_M01896 TRANSFAC + 102033282 102033291 7.0E-06 TTTTGCAATC 10 V_RARA_03_M02787 TRANSFAC + 102028842 102028857 6.0E-06 TGCCAAAGGTCACACC 16 V_DMRT2_01_M01147 TRANSFAC - 102032173 102032188 6.0E-06 TAGTAAAATACATTCA 16 V_SOX2_01_M02246 TRANSFAC - 102032085 102032099 7.0E-06 ACATTATTATGGAAA 15 V_SATB1_01_M01232 TRANSFAC + 102032181 102032192 9.0E-06 TTTTACTAACAA 12 V_PITX2_01_M01447 TRANSFAC + 102032421 102032437 3.0E-06 GGAGGGGATTTATTACT 17 V_HOXA10_01_M01464 TRANSFAC + 102032389 102032404 1.0E-06 TCTGTAATAAAACTTG 16 V_GATA1_02_M00126 TRANSFAC + 102031977 102031990 3.0E-06 TTCAAGATAATGTA 14 V_GATA1_02_M00126 TRANSFAC + 102032070 102032083 2.0E-06 GCAGAGATAAGGGT 14 V_TCF3_05_M02920 TRANSFAC - 102032153 102032167 3.0E-06 CTCCAAATAAAAATT 15 V_COUP_DR1_Q6_M00765 TRANSFAC - 102028841 102028853 2.0E-06 TGACCTTTGGCAA 13 V_OTX1_01_M01366 TRANSFAC + 102032421 102032437 1.0E-06 GGAGGGGATTTATTACT 17 V_CEBPA_Q6_M01866 TRANSFAC + 102033279 102033291 4.0E-06 GTGTTTTGCAATC 13 V_HOXC9_01_M01416 TRANSFAC + 102032388 102032403 7.0E-06 ATCTGTAATAAAACTT 16 V_OCT4_01_M01125 TRANSFAC - 102032084 102032098 2.0E-06 CATTATTATGGAAAC 15 V_OCT4_01_M01125 TRANSFAC + 102032220 102032234 6.0E-06 ATTTGTCATGGAAGT 15

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.