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NKX2-2 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS Motifs 4821 NK2 homeobox 2 chr20 - 21494164 - 21499664 21494664 V_NKX22_02_M01372 V_NKX22_01_M00485 Transcription Factor Binding Sites   Download all TFBS in the NKX2-2 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints NKX2-8_homeodomain_full_monomeric_9_1 SELEX + 21495099 21495107 8.0E-06 ACACTTGAA 9 THRB_nuclearreceptor_DBD_dimeric_20_1 SELEX + 21499206 21499225 3.0E-06 GTGGCCCCACTCCAGGACAA 20 THRB_nuclearreceptor_DBD_dimeric_20_1 SELEX - 21499206 21499225 6.0E-06 TTGTCCTGGAGTGGGGCCAC 20 IRF7_IRF_DBD_dimeric_14_1 SELEX + 21491197 21491210 2.0E-06 AACAAAGTGAAAGT 14 MEF2D_MADS_DBD_dimeric_12_1 SELEX - 21490497 21490508 6.0E-06 TCTAAAAATACT 12 SRF_MADS_DBD_dimeric_12_1 SELEX + 21494723 21494734 1.0E-06 TCCATATAAGGC 12 SRF_MADS_DBD_dimeric_12_1 SELEX - 21494723 21494734 3.0E-06 GCCTTATATGGA 12 EWSR1-FLI1_MA0149.1 JASPAR + 21494776 21494793 3.0E-06 GAAAGAGAGGGAGGGAGG 18 EWSR1-FLI1_MA0149.1 JASPAR + 21494785 21494802 1.0E-06 GGAGGGAGGGAAAGAAAG 18 EWSR1-FLI1_MA0149.1 JASPAR + 21494789 21494806 6.0E-06 GGAGGGAAAGAAAGAGGG 18 EWSR1-FLI1_MA0149.1 JASPAR + 21494793 21494810 6.0E-06 GGAAAGAAAGAGGGAGGG 18 GLI2_C2H2_DBD_monomeric_14_1 SELEX - 21496599 21496612 1.0E-06 GACCACCCAGGACG 14 MEF2A_MADS_DBD_dimeric_12_1 SELEX - 21490497 21490508 9.0E-06 TCTAAAAATACT 12 POU2F2_POU_DBD_monomeric_11_1 SELEX - 21495058 21495068 5.0E-06 GTATGTAAATA 11 SRF_MA0083.1 JASPAR + 21494722 21494733 1.0E-06 GTCCATATAAGG 12 SRF_MA0083.1 JASPAR - 21494724 21494735 1.0E-05 AGCCTTATATGG 12 MEF2B_MADS_full_dimeric_12_1 SELEX - 21490497 21490508 7.0E-06 TCTAAAAATACT 12 IRF1_MA0050.1 JASPAR + 21491199 21491210 2.0E-06 CAAAGTGAAAGT 12 Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1 SELEX + 21491156 21491171 6.0E-06 CCCCACCCACCCACTT 16 SP4_C2H2_full_monomeric_17_1 SELEX - 21494886 21494902 4.0E-06 CAAGACCCGCCCACACG 17 NFATC1_NFAT_full_dimeric_20_1 SELEX - 21496135 21496154 7.0E-06 CCGGGAAAGTTCAGTTCCCA 20 ZSCAN4_C2H2_full_monomeric_15_1 SELEX + 21495094 21495108 4.0E-06 TCCACACACTTGAAA 15 INSM1_MA0155.1 JASPAR - 21495541 21495552 9.0E-06 TGGAAGGGGGCG 12 PRDM1_C2H2_full_monomeric-or-dimeric_15_1 SELEX + 21491198 21491212 1.0E-06 ACAAAGTGAAAGTCA 15 Pou5f1_MA0142.1 JASPAR - 21495123 21495137 6.0E-06 TTTTAAGATGCAATT 15 SRF_MADS_full_dimeric_16_1 SELEX + 21494721 21494736 5.0E-06 AGTCCATATAAGGCTG 16 SRF_MADS_full_dimeric_16_1 SELEX - 21494721 21494736 9.0E-06 CAGCCTTATATGGACT 16 POU2F1_POU_DBD_monomeric_12_1 SELEX - 21495058 21495069 6.0E-06 TGTATGTAAATA 12 ZNF524_C2H2_full_monomeric_14_1 SELEX + 21495732 21495745 7.0E-06 GTCGGACCCTGGCC 14 ELF5_MA0136.1 JASPAR + 21495581 21495589 2.0E-06 TATTTCCTT 9 FOXO6_forkhead_DBD_dimeric_14_1 SELEX + 21499249 21499262 8.0E-06 GTTTACCTGTTTAC 14 Foxj3_forkhead_DBD_dimeric_13_1 SELEX + 21496621 21496633 2.0E-06 GCAAACACAAATA 13 RREB1_MA0073.1 JASPAR + 21491155 21491174 1.0E-06 CCCCCACCCACCCACTTTCT 20 RREB1_MA0073.1 JASPAR + 21495600 21495619 4.0E-06 CCCCCCACCTCCCACCCCCA 20 RREB1_MA0073.1 JASPAR + 21495604 21495623 4.0E-06 CCACCTCCCACCCCCAACCC 20 RREB1_MA0073.1 JASPAR + 21495614 21495633 7.0E-06 CCCCCAACCCCCCGCCTCCA 20 V_DMRT4_01_M01149 TRANSFAC + 21491192 21491204 0.0E+00 AATGTAACAAAGT 13 V_SRF_Q6_M00186 TRANSFAC + 21494722 21494735 0.0E+00 GTCCATATAAGGCT 14 V_SRF_Q6_M00186 TRANSFAC - 21494722 21494735 7.0E-06 AGCCTTATATGGAC 14 V_KLF15_Q2_M01714 TRANSFAC - 21495618 21495631 8.0E-06 GAGGCGGGGGGTTG 14 V_TEL1_02_M02070 TRANSFAC + 21494547 21494556 5.0E-06 CGCGGAAATG 10 V_HSF1_Q6_M01023 TRANSFAC + 21498537 21498553 4.0E-06 CCTCCGGAGGGTTCTTC 17 V_ATF5_01_M01295 TRANSFAC - 21490890 21490900 7.0E-06 CCTCTCCCTTC 11 V_FOXA2_04_M02749 TRANSFAC - 21495053 21495069 8.0E-06 TGTATGTAAATACTGGG 17 V_DMRT3_01_M01148 TRANSFAC - 21491190 21491204 2.0E-06 ACTTTGTTACATTTG 15 V_MMEF2_Q6_M00405 TRANSFAC - 21490496 21490511 3.0E-06 GTTTCTAAAAATACTT 16 V_POU5F1_02_M02245 TRANSFAC - 21495123 21495137 6.0E-06 TTTTAAGATGCAATT 15 V_DR4_Q2_M00965 TRANSFAC + 21495815 21495831 9.0E-06 TGCCCTCTATTATCCCT 17 V_ISL2_01_M01328 TRANSFAC + 21495570 21495585 8.0E-06 AAAGACTCATTTATTT 16 V_IRF2_Q6_M01882 TRANSFAC + 21491197 21491212 1.0E-06 AACAAAGTGAAAGTCA 16 V_NFAT3_Q3_M01734 TRANSFAC - 21494691 21494700 6.0E-06 ATTTTTTCCT 10 V_GLI1_Q2_M01042 TRANSFAC - 21496603 21496612 3.0E-06 GACCACCCAG 10 V_OCT1_01_M00135 TRANSFAC - 21495054 21495072 6.0E-06 CTTTGTATGTAAATACTGG 19 V_NKX25_Q6_M02108 TRANSFAC + 21495098 21495108 1.0E-06 CACACTTGAAA 11 V_CEBP_01_M00159 TRANSFAC + 21495562 21495574 4.0E-06 TATTTGCTAAAGA 13 V_POU2F3_01_M01476 TRANSFAC - 21495055 21495070 3.0E-06 TTGTATGTAAATACTG 16 V_GLI1_01_M01702 TRANSFAC - 21496602 21496612 2.0E-06 GACCACCCAGG 11 V_HNF3_Q6_01_M01012 TRANSFAC + 21499243 21499260 8.0E-06 CTCAGTGTTTACCTGTTT 18 V_MEF2A_Q6_M02024 TRANSFAC + 21490499 21490508 0.0E+00 TATTTTTAGA 10 V_PPARGRXRA_01_M02262 TRANSFAC + 21495782 21495796 2.0E-06 GTGGAGGAAAGGGCA 15 V_SRF_C_M00215 TRANSFAC - 21494720 21494734 0.0E+00 GCCTTATATGGACTG 15 V_GLI3_02_M01704 TRANSFAC - 21496602 21496612 2.0E-06 GACCACCCAGG 11 V_ZNF219_01_M01122 TRANSFAC + 21495612 21495623 9.0E-06 CACCCCCAACCC 12 V_GC_01_M00255 TRANSFAC + 21494888 21494901 7.0E-06 TGTGGGCGGGTCTT 14 V_EGR1_01_M00243 TRANSFAC + 21491379 21491390 9.0E-06 ATGCGGGGGAGG 12 V_FREAC3_01_M00291 TRANSFAC - 21495054 21495069 7.0E-06 TGTATGTAAATACTGG 16 V_ZIC3_01_M00450 TRANSFAC + 21496604 21496612 6.0E-06 TGGGTGGTC 9 V_FKLF_Q5_M01837 TRANSFAC - 21495608 21495617 2.0E-06 GGGGTGGGAG 10 V_SP4_03_M02810 TRANSFAC + 21495536 21495552 2.0E-06 CGACCCGCCCCCTTCCA 17 V_HOXB9_01_M01426 TRANSFAC + 21494857 21494872 9.0E-06 AGAGACATTAAAAACG 16 V_IRF3_Q3_M01279 TRANSFAC - 21491200 21491212 1.0E-06 TGACTTTCACTTT 13 V_MAZ_Q6_01_M02023 TRANSFAC + 21494782 21494795 3.0E-06 GAGGGAGGGAGGGA 14 V_MAZ_Q6_01_M02023 TRANSFAC + 21494802 21494815 2.0E-06 GAGGGAGGGAGGGG 14 V_MAZ_Q6_01_M02023 TRANSFAC - 21497622 21497635 1.0E-05 GGGTGAGGGGAGGG 14 V_HOX13_01_M00023 TRANSFAC + 21495810 21495839 7.0E-06 TTTCCTGCCCTCTATTATCCCTCCCTCTCC 30 V_NFE4_Q5_M02105 TRANSFAC + 21495830 21495841 9.0E-06 CTCCCTCTCCGG 12 V_NFE4_Q5_M02105 TRANSFAC + 21495846 21495857 0.0E+00 CTCCCTCTCCAG 12 V_SP1SP3_Q4_M01219 TRANSFAC + 21495540 21495550 4.0E-06 CCGCCCCCTTC 11 V_MEF2_04_M00233 TRANSFAC - 21490493 21490514 6.0E-06 CGGGTTTCTAAAAATACTTGGG 22 V_RREB1_01_M00257 TRANSFAC + 21491156 21491169 6.0E-06 CCCCACCCACCCAC 14 V_ZIC1_01_M00448 TRANSFAC + 21496604 21496612 6.0E-06 TGGGTGGTC 9 V_CDC5_01_M00478 TRANSFAC + 21495114 21495125 5.0E-06 GTTTTAACAAAT 12 V_SRF_Q5_02_M01007 TRANSFAC - 21494720 21494738 1.0E-06 CCCAGCCTTATATGGACTG 19 V_TEL1_01_M01993 TRANSFAC + 21494547 21494556 5.0E-06 CGCGGAAATG 10 V_INSM1_01_M02268 TRANSFAC - 21495541 21495552 9.0E-06 TGGAAGGGGGCG 12 V_SRF_03_M01304 TRANSFAC + 21494722 21494734 0.0E+00 GTCCATATAAGGC 13 V_GATA4_Q3_M00632 TRANSFAC + 21490517 21490528 4.0E-06 AGATAGAGGAGA 12 V_TFIII_Q6_M00706 TRANSFAC + 21494781 21494789 6.0E-06 AGAGGGAGG 9 V_TFIII_Q6_M00706 TRANSFAC + 21494801 21494809 6.0E-06 AGAGGGAGG 9 V_TFIII_Q6_M00706 TRANSFAC - 21495829 21495837 6.0E-06 AGAGGGAGG 9 V_TFIII_Q6_M00706 TRANSFAC - 21495845 21495853 6.0E-06 AGAGGGAGG 9 V_PTF1BETA_Q6_M00657 TRANSFAC - 21498540 21498553 1.0E-05 GAAGAACCCTCCGG 14 V_GCNF_01_M00526 TRANSFAC + 21498668 21498685 2.0E-06 AGCGAGTTCAATGTCCTC 18 V_GLI2_01_M01703 TRANSFAC - 21496602 21496612 2.0E-06 GACCACCCAGG 11 V_IPF1_05_M01255 TRANSFAC + 21494859 21494870 0.0E+00 AGACATTAAAAA 12 V_OCT2_01_M01368 TRANSFAC - 21495055 21495070 3.0E-06 TTGTATGTAAATACTG 16 V_CACBINDINGPROTEIN_Q6_M00720 TRANSFAC + 21491387 21491395 8.0E-06 GAGGGTGGG 9 V_CAAT_C_M00200 TRANSFAC - 21495439 21495463 7.0E-06 ATCAATTACTTGCCTTGTCATTTCT 25 V_FOXL1_04_M02753 TRANSFAC - 21495053 21495069 9.0E-06 TGTATGTAAATACTGGG 17 V_VDR_Q6_M00961 TRANSFAC - 21491349 21491360 8.0E-06 CTGTCTGAACCC 12 V_SRF_01_M00152 TRANSFAC + 21494720 21494737 4.0E-06 CAGTCCATATAAGGCTGG 18 V_STAT1STAT1_Q3_M01212 TRANSFAC - 21494532 21494544 4.0E-06 CTTTCAAAGAAGA 13 V_FOX_Q2_M00809 TRANSFAC + 21495559 21495571 8.0E-06 CTTTATTTGCTAA 13 V_SRF_Q5_01_M00922 TRANSFAC + 21494724 21494738 2.0E-06 CCATATAAGGCTGGG 15 V_SRF_Q4_M00810 TRANSFAC + 21494723 21494740 5.0E-06 TCCATATAAGGCTGGGCT 18 V_SREBP_Q3_M00776 TRANSFAC + 21490713 21490724 8.0E-06 GAGCTCACCCCA 12 V_IRF1_Q6_01_M01881 TRANSFAC - 21491198 21491211 3.0E-06 GACTTTCACTTTGT 14 V_SRF_02_M01257 TRANSFAC + 21494722 21494739 3.0E-06 GTCCATATAAGGCTGGGC 18 V_EWSR1FLI1_01_M02252 TRANSFAC + 21494776 21494793 3.0E-06 GAAAGAGAGGGAGGGAGG 18 V_EWSR1FLI1_01_M02252 TRANSFAC + 21494785 21494802 1.0E-06 GGAGGGAGGGAAAGAAAG 18 V_EWSR1FLI1_01_M02252 TRANSFAC + 21494789 21494806 6.0E-06 GGAGGGAAAGAAAGAGGG 18 V_EWSR1FLI1_01_M02252 TRANSFAC + 21494793 21494810 6.0E-06 GGAAAGAAAGAGGGAGGG 18 V_HNF3B_Q6_M02014 TRANSFAC + 21495561 21495569 1.0E-05 TTATTTGCT 9 V_GLI_Q2_M01037 TRANSFAC + 21496602 21496613 3.0E-06 CCTGGGTGGTCG 12 V_ELF5_04_M02241 TRANSFAC + 21495581 21495589 2.0E-06 TATTTCCTT 9 V_EHF_07_M02849 TRANSFAC + 21497533 21497548 3.0E-06 ATGTAGTTCCCAACTT 16 V_TCF11MAFG_01_M00284 TRANSFAC + 21495438 21495459 6.0E-06 TAGAAATGACAAGGCAAGTAAT 22 V_ZIC2_01_M00449 TRANSFAC + 21496604 21496612 6.0E-06 TGGGTGGTC 9 V_FOXK1_03_M02752 TRANSFAC - 21499243 21499259 9.0E-06 AACAGGTAAACACTGAG 17 V_SOX9_Q4_M01284 TRANSFAC + 21495065 21495075 3.0E-06 ATACAAAGGGC 11 PPARG_RXRA_MA0065.2 JASPAR + 21495782 21495796 2.0E-06 GTGGAGGAAAGGGCA 15 V_DMRT5_01_M01150 TRANSFAC - 21491189 21491203 3.0E-06 CTTTGTTACATTTGA 15 V_TR4_03_M01782 TRANSFAC - 21491145 21491157 7.0E-06 GGGTCTGAGGTTA 13

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.