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MVK Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 4598 mevalonate kinase chr12 + 110006499 - 110011999 110011499 Transcription Factor Binding Sites   Download all TFBS in the MVK promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints Hoxc10_homeodomain_DBD_monomeric_10_2 SELEX - 110011384 110011393 6.0E-06 CCAATAAAAA 10 NF-kappaB_MA0061.1 JASPAR + 110011845 110011854 9.0E-06 GGGGATTCCC 10 MYF6_bHLH_full_dimeric_10_1 SELEX + 110016433 110016442 1.0E-06 AACAGCTGTT 10 MYF6_bHLH_full_dimeric_10_1 SELEX - 110016433 110016442 1.0E-06 AACAGCTGTT 10 Hoxd9_homeodomain_DBD_monomeric_10_1 SELEX - 110011384 110011393 9.0E-06 CCAATAAAAA 10 FOXG1_forkhead_DBD_dimeric_17_1 SELEX - 110011434 110011450 7.0E-06 TAAACCAATGGGAAACA 17 FOXG1_forkhead_DBD_dimeric_17_1 SELEX - 110016362 110016378 4.0E-06 ACCAACAAGTGTAACCT 17 RFX4_RFX_DBD_dimeric_16_1 SELEX + 110011010 110011025 0.0E+00 CGTTGCCATGGTGACG 16 RFX4_RFX_DBD_dimeric_16_1 SELEX - 110011010 110011025 0.0E+00 CGTCACCATGGCAACG 16 RFX4_RFX_DBD_dimeric_16_1 SELEX + 110011084 110011099 4.0E-06 CGTACCCATGGCGACG 16 NFKB1_MA0105.1 JASPAR + 110011845 110011855 0.0E+00 GGGGATTCCCC 11 NFKB1_MA0105.1 JASPAR - 110011845 110011855 1.0E-06 GGGGAATCCCC 11 STAT1_MA0137.2 JASPAR - 110011870 110011884 3.0E-06 CATTTCTTAGAAAAA 15 NFYA_MA0060.1 JASPAR - 110011547 110011562 0.0E+00 GCCAGCCAATCAGAGC 16 XBP1_bZIP_DBD_dimeric_12_1 SELEX + 110011019 110011030 7.0E-06 GGTGACGTCAGA 12 Creb5_bZIP_DBD_dimeric_12_1 SELEX - 110011019 110011030 7.0E-06 TCTGACGTCACC 12 TFAP2C_TFAP_full_dimeric_13_1 SELEX + 110011168 110011180 8.0E-06 CGCCCTGAGGGCC 13 NFKB2_NFAT_DBD_dimeric_13_1 SELEX + 110011844 110011856 0.0E+00 AGGGGATTCCCCG 13 NFKB2_NFAT_DBD_dimeric_13_1 SELEX - 110011844 110011856 0.0E+00 CGGGGAATCCCCT 13 JDP2_bZIP_full_dimeric_12_1 SELEX - 110011019 110011030 6.0E-06 TCTGACGTCACC 12 IRF1_MA0050.1 JASPAR - 110011376 110011387 2.0E-06 AAAATTGAAACC 12 HOXD11_homeodomain_DBD_monomeric_10_2 SELEX - 110011385 110011394 1.0E-05 ACCAATAAAA 10 Rfx3_RFX_DBD_dimeric_16_1 SELEX + 110011010 110011025 0.0E+00 CGTTGCCATGGTGACG 16 Rfx3_RFX_DBD_dimeric_16_1 SELEX - 110011010 110011025 0.0E+00 CGTCACCATGGCAACG 16 Rfx3_RFX_DBD_dimeric_16_1 SELEX + 110011084 110011099 4.0E-06 CGTACCCATGGCGACG 16 Rfx3_RFX_DBD_dimeric_16_1 SELEX - 110011084 110011099 6.0E-06 CGTCGCCATGGGTACG 16 HOXD13_homeodomain_DBD_monomeric_10_1 SELEX - 110011384 110011393 0.0E+00 CCAATAAAAA 10 FIGLA_bHLH_DBD_dimeric_10_1 SELEX + 110016433 110016442 9.0E-06 AACAGCTGTT 10 FIGLA_bHLH_DBD_dimeric_10_1 SELEX - 110016433 110016442 9.0E-06 AACAGCTGTT 10 ATF7_bZIP_DBD_dimeric_14_1 SELEX + 110011018 110011031 1.0E-05 TGGTGACGTCAGAA 14 ATF7_bZIP_DBD_dimeric_14_1 SELEX - 110011018 110011031 9.0E-06 TTCTGACGTCACCA 14 HOXC11_homeodomain_full_monomeric_11_2 SELEX - 110011384 110011394 3.0E-06 ACCAATAAAAA 11 Ascl2_bHLH_DBD_dimeric_10_1 SELEX + 110016433 110016442 3.0E-06 AACAGCTGTT 10 Ascl2_bHLH_DBD_dimeric_10_1 SELEX - 110016433 110016442 3.0E-06 AACAGCTGTT 10 Tcf21_bHLH_DBD_dimeric_14_1 SELEX + 110016431 110016444 1.0E-06 TTAACAGCTGTTCC 14 Tcf21_bHLH_DBD_dimeric_14_1 SELEX - 110016431 110016444 0.0E+00 GGAACAGCTGTTAA 14 CREB3_bZIP_full_dimeric_14_1 SELEX + 110011018 110011031 4.0E-06 TGGTGACGTCAGAA 14 CREB3_bZIP_full_dimeric_14_1 SELEX - 110011018 110011031 1.0E-06 TTCTGACGTCACCA 14 CREB3_bZIP_full_dimeric_14_1 SELEX - 110011037 110011050 8.0E-06 AGGTGACGTCTCCA 14 TFAP2A_TFAP_DBD_dimeric_13_1 SELEX + 110011581 110011593 9.0E-06 TCCCCTTGAGGCA 13 HOXA13_homeodomain_full_monomeric_10_1 SELEX - 110011384 110011393 0.0E+00 CCAATAAAAA 10 Mycn_MA0104.2 JASPAR + 110010997 110011006 8.0E-06 CCCACGTGGC 10 NFKB1_NFAT_DBD_dimeric_13_1 SELEX + 110011844 110011856 0.0E+00 AGGGGATTCCCCG 13 NFKB1_NFAT_DBD_dimeric_13_1 SELEX - 110011844 110011856 0.0E+00 CGGGGAATCCCCT 13 RFX2_RFX_DBD_dimeric_16_1 SELEX + 110011010 110011025 0.0E+00 CGTTGCCATGGTGACG 16 RFX2_RFX_DBD_dimeric_16_1 SELEX - 110011010 110011025 0.0E+00 CGTCACCATGGCAACG 16 RFX2_RFX_DBD_dimeric_16_1 SELEX + 110011084 110011099 3.0E-06 CGTACCCATGGCGACG 16 RFX2_RFX_DBD_dimeric_16_1 SELEX - 110011084 110011099 3.0E-06 CGTCGCCATGGGTACG 16 RFX5_RFX_DBD_dimeric_16_3 SELEX + 110011010 110011025 0.0E+00 CGTTGCCATGGTGACG 16 RFX5_RFX_DBD_dimeric_16_3 SELEX - 110011010 110011025 0.0E+00 CGTCACCATGGCAACG 16 MYBL1_MYB_DBD_dimeric_12_1 SELEX - 110011444 110011455 6.0E-06 TCCGTTAAACCA 12 IRF9_IRF_full_trimeric_15_1 SELEX - 110011376 110011390 9.0E-06 ATAAAAATTGAAACC 15 Hoxd9_homeodomain_DBD_monomeric_9_1 SELEX - 110011385 110011393 6.0E-06 CCAATAAAA 9 TFAP2B_TFAP_DBD_dimeric_13_1 SELEX + 110011581 110011593 5.0E-06 TCCCCTTGAGGCA 13 TFAP4_bHLH_full_dimeric_10_1 SELEX + 110016433 110016442 1.0E-06 AACAGCTGTT 10 TFAP4_bHLH_full_dimeric_10_1 SELEX - 110016433 110016442 1.0E-06 AACAGCTGTT 10 SOX21_HMG_DBD_dimeric_16_1 SELEX + 110011379 110011394 1.0E-05 TTCAATTTTTATTGGT 16 HOXC13_homeodomain_DBD_monomeric_10_1 SELEX - 110011384 110011393 0.0E+00 CCAATAAAAA 10 HMX2_homeodomain_DBD_monomeric_11_1 SELEX - 110011384 110011394 5.0E-06 ACCAATAAAAA 11 CPEB1_RRM_full_monomeric_8_1 SELEX - 110011384 110011391 4.0E-06 AATAAAAA 8 Hoxa11_homeodomain_DBD_monomeric_11_1 SELEX - 110011384 110011394 6.0E-06 ACCAATAAAAA 11 BATF3_bZIP_DBD_dimeric_14_1 SELEX + 110011018 110011031 2.0E-06 TGGTGACGTCAGAA 14 BATF3_bZIP_DBD_dimeric_14_1 SELEX - 110011018 110011031 3.0E-06 TTCTGACGTCACCA 14 MSC_bHLH_full_dimeric_10_1 SELEX + 110016433 110016442 1.0E-06 AACAGCTGTT 10 MSC_bHLH_full_dimeric_10_1 SELEX - 110016433 110016442 1.0E-06 AACAGCTGTT 10 HOXA10_homeodomain_DBD_monomeric_11_1 SELEX - 110011384 110011394 9.0E-06 ACCAATAAAAA 11 HOXB13_homeodomain_DBD_monomeric_10_1 SELEX - 110011384 110011393 0.0E+00 CCAATAAAAA 10 V_HOXA9_01_M01351 TRANSFAC - 110011380 110011396 3.0E-06 GAACCAATAAAAATTGA 17 V_E2A_Q6_01_M02088 TRANSFAC - 110011112 110011124 8.0E-06 GAACACCTGCCGT 13 V_STAT5A_Q6_M01890 TRANSFAC + 110011869 110011881 0.0E+00 GTTTTTCTAAGAA 13 V_STAT5A_Q6_M01890 TRANSFAC - 110011873 110011885 0.0E+00 CCATTTCTTAGAA 13 V_APOLYA_B_M00310 TRANSFAC + 110010866 110010880 4.0E-06 AATAAACTGCTTTGG 15 TAL1_TCF3_MA0091.1 JASPAR + 110016431 110016442 9.0E-06 TTAACAGCTGTT 12 TAL1_TCF3_MA0091.1 JASPAR - 110016433 110016444 5.0E-06 GGAACAGCTGTT 12 V_BCL6B_03_M02740 TRANSFAC + 110011870 110011885 2.0E-06 TTTTTCTAAGAAATGG 16 V_SREBP2_Q6_M01177 TRANSFAC + 110011042 110011053 5.0E-06 ACGTCACCTGAC 12 V_CREB_Q4_M00178 TRANSFAC - 110011019 110011030 5.0E-06 TCTGACGTCACC 12 V_IRF_Q6_01_M00972 TRANSFAC - 110011377 110011387 3.0E-06 AAAATTGAAAC 11 V_IRF2_Q6_M01882 TRANSFAC - 110011374 110011389 1.0E-05 TAAAAATTGAAACCTG 16 V_HNF4_Q6_M00967 TRANSFAC + 110016418 110016426 1.0E-05 AAAGTCCAG 9 V_RFX4_03_M02789 TRANSFAC - 110011008 110011022 4.0E-06 CACCATGGCAACGTG 15 V_YY1_Q6_M00793 TRANSFAC + 110010827 110010835 7.0E-06 GCCATCTTT 9 V_P53_DECAMER_Q2_M00761 TRANSFAC - 110011429 110011438 7.0E-06 AAACAAGTCC 10 V_AP2_Q6_01_M00915 TRANSFAC + 110011243 110011255 1.0E-05 GGCTCCCCAGGCC 13 V_AP2_Q6_01_M00915 TRANSFAC + 110011261 110011273 1.0E-05 GGCTCCCCAGGCC 13 V_STAT5B_01_M00459 TRANSFAC + 110011870 110011884 3.0E-06 TTTTTCTAAGAAATG 15 V_STAT5B_01_M00459 TRANSFAC - 110011870 110011884 2.0E-06 CATTTCTTAGAAAAA 15 V_JUNDM2_03_M02772 TRANSFAC - 110011017 110011032 4.0E-06 GTTCTGACGTCACCAT 16 V_HOXD13_01_M01404 TRANSFAC - 110011381 110011396 0.0E+00 GAACCAATAAAAATTG 16 V_CMYC_02_M01154 TRANSFAC + 110010996 110011007 9.0E-06 GCCCACGTGGCC 12 V_NFY_C_M00209 TRANSFAC + 110011549 110011562 1.0E-06 TCTGATTGGCTGGC 14 V_ZFP105_03_M02827 TRANSFAC - 110011381 110011395 4.0E-06 AACCAATAAAAATTG 15 V_HOXB13_01_M01467 TRANSFAC - 110011381 110011396 0.0E+00 GAACCAATAAAAATTG 16 V_POLY_C_M00212 TRANSFAC + 110010865 110010882 7.0E-06 GAATAAACTGCTTTGGAG 18 V_HOXB9_01_M01426 TRANSFAC - 110011381 110011396 0.0E+00 GAACCAATAAAAATTG 16 V_E47_02_M00071 TRANSFAC + 110016430 110016445 1.0E-06 CTTAACAGCTGTTCCA 16 V_E47_02_M00071 TRANSFAC - 110016430 110016445 8.0E-06 TGGAACAGCTGTTAAG 16 V_AP2BETA_Q3_M01858 TRANSFAC - 110011245 110011260 6.0E-06 GTCTTGGCCTGGGGAG 16 V_IRF_Q6_M00772 TRANSFAC + 110011373 110011387 2.0E-06 TCAGGTTTCAATTTT 15 V_SREBP_Q6_M01168 TRANSFAC + 110011400 110011414 6.0E-06 GTTCTCACCCCAGGG 15 V_ASCL2_03_M02737 TRANSFAC + 110016430 110016446 1.0E-06 CTTAACAGCTGTTCCAT 17 V_ISRE_01_M00258 TRANSFAC + 110011375 110011389 4.0E-06 AGGTTTCAATTTTTA 15 V_CREBATF_Q6_M00981 TRANSFAC + 110011020 110011028 9.0E-06 GTGACGTCA 9 V_AP4_Q5_M00175 TRANSFAC + 110016433 110016442 9.0E-06 AACAGCTGTT 10 V_AP4_Q5_M00175 TRANSFAC - 110016433 110016442 9.0E-06 AACAGCTGTT 10 V_NFKAPPAB50_01_M00051 TRANSFAC + 110011845 110011854 2.0E-06 GGGGATTCCC 10 V_IRF4_03_M02768 TRANSFAC - 110011373 110011387 8.0E-06 AAAATTGAAACCTGA 15 V_ATF3_Q6_M00513 TRANSFAC - 110011062 110011075 8.0E-06 CCGTGAGGTCACCG 14 V_STAT4_Q5_M02117 TRANSFAC - 110011872 110011881 9.0E-06 TTCTTAGAAA 10 V_STAT4_Q5_M02117 TRANSFAC + 110011873 110011882 1.0E-06 TTCTAAGAAA 10 V_ISGF3G_03_M02771 TRANSFAC - 110011374 110011388 7.0E-06 AAAAATTGAAACCTG 15 V_MYCN_01_M02259 TRANSFAC + 110010997 110011006 8.0E-06 CCCACGTGGC 10 V_CREB_Q2_01_M00916 TRANSFAC + 110011019 110011032 6.0E-06 GGTGACGTCAGAAC 14 V_TBX5_01_M01019 TRANSFAC - 110011490 110011501 9.0E-06 ATAGGTGTTGCA 12 V_CREM_Q6_M01820 TRANSFAC - 110011018 110011028 0.0E+00 TGACGTCACCA 11 V_VJUN_01_M00036 TRANSFAC + 110011017 110011032 2.0E-06 ATGGTGACGTCAGAAC 16 V_GFI1_Q6_M01067 TRANSFAC - 110011818 110011830 8.0E-06 CAAAATCACGACT 13 V_ALPHACP1_01_M00687 TRANSFAC - 110011550 110011560 1.0E-06 CAGCCAATCAG 11 V_T3R_01_M00239 TRANSFAC - 110011060 110011075 5.0E-06 CCGTGAGGTCACCGCG 16 V_IRF5_03_M02769 TRANSFAC - 110011374 110011388 9.0E-06 AAAAATTGAAACCTG 15 V_NFYC_Q5_M02107 TRANSFAC - 110011547 110011560 0.0E+00 CAGCCAATCAGAGC 14 V_CREBP1_Q2_M00179 TRANSFAC + 110011019 110011030 6.0E-06 GGTGACGTCAGA 12 V_AREB6_02_M00413 TRANSFAC + 110011146 110011157 4.0E-06 ACTCACCTGTCC 12 V_TAL1ALPHAE47_01_M00066 TRANSFAC - 110016430 110016445 7.0E-06 TGGAACAGCTGTTAAG 16 V_ATF1_03_M02738 TRANSFAC + 110011017 110011032 2.0E-06 ATGGTGACGTCAGAAC 16 V_ATF1_03_M02738 TRANSFAC - 110011017 110011032 3.0E-06 GTTCTGACGTCACCAT 16 V_PARP_Q3_M01211 TRANSFAC - 110011869 110011878 8.0E-06 TTAGAAAAAC 10 V_DMRT7_01_M01151 TRANSFAC + 110011375 110011388 9.0E-06 AGGTTTCAATTTTT 14 V_NFY_01_M00287 TRANSFAC - 110011547 110011562 0.0E+00 GCCAGCCAATCAGAGC 16 V_TCFAP2B_03_M02820 TRANSFAC + 110011786 110011799 9.0E-06 TTGCCCCGAGGGAT 14 V_STAT1STAT1_Q3_M01212 TRANSFAC + 110011871 110011883 8.0E-06 TTTTCTAAGAAAT 13 V_E47_01_M00002 TRANSFAC + 110011112 110011126 1.0E-06 ACGGCAGGTGTTCGA 15 V_MEF3_B_M00319 TRANSFAC + 110011370 110011382 4.0E-06 CGCTCAGGTTTCA 13 V_IRF1_Q6_01_M01881 TRANSFAC + 110011375 110011388 3.0E-06 AGGTTTCAATTTTT 14 V_NFKAPPAB_01_M00054 TRANSFAC + 110011845 110011854 9.0E-06 GGGGATTCCC 10 V_STAT5A_01_M00457 TRANSFAC + 110011870 110011884 4.0E-06 TTTTTCTAAGAAATG 15 V_STAT5A_01_M00457 TRANSFAC - 110011870 110011884 7.0E-06 CATTTCTTAGAAAAA 15 V_PPARG_02_M00515 TRANSFAC + 110016353 110016375 5.0E-06 AAGTGGCTCAGGTTACACTTGTT 23 V_CREB_02_M00113 TRANSFAC + 110011017 110011028 4.0E-06 ATGGTGACGTCA 12 V_MAFK_04_M02880 TRANSFAC - 110011376 110011390 6.0E-06 ATAAAAATTGAAACC 15 V_NFYA_Q5_M02106 TRANSFAC - 110011547 110011560 0.0E+00 CAGCCAATCAGAGC 14 V_HOXD10_01_M01375 TRANSFAC - 110011380 110011396 6.0E-06 GAACCAATAAAAATTGA 17 V_TCF3_05_M02920 TRANSFAC - 110011382 110011396 1.0E-05 GAACCAATAAAAATT 15 V_STAT1_05_M01260 TRANSFAC + 110011870 110011891 1.0E-06 TTTTTCTAAGAAATGGGGATCA 22 V_RFX1_02_M00281 TRANSFAC - 110011009 110011026 0.0E+00 ACGTCACCATGGCAACGT 18

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