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MEFV Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 4210 Mediterranean fever chr16 - 3306127 - 3311627 3306627 Transcription Factor Binding Sites   Download all TFBS in the MEFV promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints HSF2_HSF_DBD_trimeric_13_1 SELEX - 3307340 3307352 1.0E-06 GTCTAGAATGTTC 13 THRB_nuclearreceptor_DBD_dimeric_20_1 SELEX + 3309548 3309567 0.0E+00 GTGACCTTATTTGGGGTGAC 20 THRB_nuclearreceptor_DBD_dimeric_20_1 SELEX - 3309548 3309567 0.0E+00 GTCACCCCAAATAAGGTCAC 20 MSX2_homeodomain_DBD_dimeric_18_1 SELEX - 3309484 3309501 3.0E-06 TTGATTATTAAACACTTA 18 ESRRA_nuclearreceptor_DBD_dimeric_19_1 SELEX - 3309466 3309484 5.0E-06 AAATGACGTTAGAAGGGCA 19 BARX1_homeodomain_DBD_dimeric_17_1 SELEX - 3309484 3309500 0.0E+00 TGATTATTAAACACTTA 17 LHX6_homeodomain_full_dimeric_16_1 SELEX + 3308909 3308924 9.0E-06 CAATGAGCTGTGATTG 16 HSF1_HSF_full_trimeric_13_1 SELEX - 3307340 3307352 1.0E-06 GTCTAGAATGTTC 13 SRF_MADS_DBD_dimeric_12_1 SELEX + 3309551 3309562 7.0E-06 ACCTTATTTGGG 12 SRF_MADS_DBD_dimeric_12_1 SELEX - 3309551 3309562 6.0E-06 CCCAAATAAGGT 12 LHX2_homeodomain_DBD_dimeric_15_1 SELEX - 3310088 3310102 2.0E-06 AAGTTAAGCTAATTG 15 CEBPA_MA0102.2 JASPAR + 3309303 3309311 4.0E-06 TTTTGCAAT 9 RARA_nuclearreceptor_DBD_dimeric_18_2 SELEX + 3307142 3307159 4.0E-06 GAGGCCAGAAGGGCACTG 18 ISX_homeodomain_DBD_dimeric_13_1 SELEX - 3310087 3310099 8.0E-06 TTAAGCTAATTGT 13 SRF_MA0083.1 JASPAR + 3309550 3309561 3.0E-06 GACCTTATTTGG 12 ESRRG_nuclearreceptor_full_dimeric_18_1 SELEX - 3309466 3309483 4.0E-06 AATGACGTTAGAAGGGCA 18 HSF4_HSF_DBD_trimeric_13_1 SELEX - 3307340 3307352 1.0E-06 GTCTAGAATGTTC 13 HSF4_HSF_DBD_trimeric_13_1 SELEX + 3309432 3309444 9.0E-06 TTCCAGTAATTTC 13 NR4A2_nuclearreceptor_full_dimeric_16_1 SELEX + 3309466 3309481 1.0E-05 TGCCCTTCTAACGTCA 16 ATF4_bZIP_DBD_dimeric_13_1 SELEX - 3310017 3310029 9.0E-06 CAGTGATGCAATC 13 Msx3_homeodomain_DBD_dimeric_18_1 SELEX - 3309484 3309501 5.0E-06 TTGATTATTAAACACTTA 18 FEV_MA0156.1 JASPAR + 3306696 3306703 1.0E-05 CAGGAAAT 8 SRF_MADS_full_dimeric_16_1 SELEX + 3309549 3309564 5.0E-06 TGACCTTATTTGGGGT 16 SRF_MADS_full_dimeric_16_1 SELEX - 3309549 3309564 1.0E-06 ACCCCAAATAAGGTCA 16 HMX2_homeodomain_DBD_monomeric_11_1 SELEX - 3309481 3309491 3.0E-06 AACACTTAAAT 11 GBX2_homeodomain_DBD_dimeric_14_1 SELEX + 3309484 3309497 8.0E-06 TAAGTGTTTAATAA 14 GBX2_homeodomain_DBD_dimeric_14_1 SELEX - 3309484 3309497 5.0E-06 TTATTAAACACTTA 14 IRF5_IRF_full_dimeric_14_1 SELEX + 3309239 3309252 1.0E-06 CTGATACCAAAACC 14 REST_MA0138.2 JASPAR - 3306576 3306596 1.0E-06 CTCAGCACCATGGCTAAGACC 21 POU3F3_POU_DBD_dimeric_12_1 SELEX + 3309490 3309501 1.0E-06 TTTAATAATCAA 12 POU3F3_POU_DBD_dimeric_12_1 SELEX - 3309490 3309501 3.0E-06 TTGATTATTAAA 12 MSX1_homeodomain_DBD_dimeric_18_1 SELEX - 3309484 3309501 5.0E-06 TTGATTATTAAACACTTA 18 RARG_nuclearreceptor_full_dimeric_16_1 SELEX + 3307142 3307157 6.0E-06 GAGGCCAGAAGGGCAC 16 Foxj3_forkhead_DBD_dimeric_13_1 SELEX + 3310067 3310079 6.0E-06 AAAAAAAAAAAAA 13 NFE2L2_MA0150.1 JASPAR + 3308946 3308956 2.0E-06 GTGACACAGCA 11 HMX1_homeodomain_DBD_monomeric_11_1 SELEX - 3309481 3309491 5.0E-06 AACACTTAAAT 11 V_NFAT_Q4_01_M00935 TRANSFAC - 3306784 3306793 7.0E-06 CTGGAAAATC 10 V_CEBPG_Q6_M00622 TRANSFAC + 3309252 3309264 7.0E-06 CCCATGACAGAAT 13 V_DBX1_01_M01483 TRANSFAC + 3309484 3309500 6.0E-06 TAAGTGTTTAATAATCA 17 V_DBX1_01_M01483 TRANSFAC + 3310062 3310078 3.0E-06 TATTTAAAAAAAAAAAA 17 V_XFD1_01_M00267 TRANSFAC + 3308188 3308201 5.0E-06 TTTATAAACACTTC 14 TAL1_TCF3_MA0091.1 JASPAR - 3306559 3306570 8.0E-06 TGACCATCTGCT 12 V_CEBP_Q3_M00770 TRANSFAC + 3309300 3309311 0.0E+00 ATATTTTGCAAT 12 V_SIX6_02_M01398 TRANSFAC + 3309075 3309091 1.0E-06 AATGGGGTATCACTGGG 17 V_HMGIY_Q3_M01010 TRANSFAC - 3310067 3310081 1.0E-05 ACTTTTTTTTTTTTT 15 V_ETS_B_M00340 TRANSFAC - 3308193 3308206 3.0E-06 AGGAGGAAGTGTTT 14 V_MAFB_03_M02879 TRANSFAC - 3309033 3309047 2.0E-06 AAATTCCAAAAATCT 15 V_MAFB_03_M02879 TRANSFAC - 3309299 3309313 0.0E+00 CAATTGCAAAATATC 15 V_PROP1_01_M01294 TRANSFAC - 3309454 3309464 3.0E-06 TAATTCTATTT 11 V_HNF4_Q6_M00967 TRANSFAC - 3309383 3309391 2.0E-06 AAAGTCCAA 9 V_CEBP_Q2_M00190 TRANSFAC - 3309300 3309313 5.0E-06 CAATTGCAAAATAT 14 V_MAF_Q6_M00648 TRANSFAC - 3308192 3308207 5.0E-06 TAGGAGGAAGTGTTTA 16 V_PITX2_Q6_M02114 TRANSFAC + 3309576 3309585 7.0E-06 TCTAAACCCA 10 V_PITX2_Q6_M02114 TRANSFAC + 3309945 3309954 1.0E-06 TGTAATCCCA 10 V_TCFAP2E_04_M02926 TRANSFAC + 3310062 3310075 0.0E+00 TATTTAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC + 3310063 3310076 5.0E-06 ATTTAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC + 3310064 3310077 4.0E-06 TTTAAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC + 3310065 3310078 1.0E-06 TTAAAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC + 3310066 3310079 0.0E+00 TAAAAAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC + 3310067 3310080 4.0E-06 AAAAAAAAAAAAAG 14 V_CDX_Q5_M00991 TRANSFAC - 3309482 3309499 4.0E-06 GATTATTAAACACTTAAA 18 V_LDSPOLYA_B_M00317 TRANSFAC + 3306754 3306769 2.0E-06 CGGCTGTGTTCTCTTC 16 V_LDSPOLYA_B_M00317 TRANSFAC + 3309484 3309499 9.0E-06 TAAGTGTTTAATAATC 16 V_HBP1_Q2_M01661 TRANSFAC - 3307334 3307342 3.0E-06 TTCAATGAA 9 V_CEBPB_01_M00109 TRANSFAC + 3306671 3306684 1.0E-06 AGGTTGTGAAATAG 14 V_CEBPB_01_M00109 TRANSFAC + 3309300 3309313 1.0E-06 ATATTTTGCAATTG 14 V_MEF2A_Q6_M02024 TRANSFAC + 3310062 3310071 4.0E-06 TATTTAAAAA 10 V_BARBIE_01_M00238 TRANSFAC - 3309409 3309423 8.0E-06 AACAAAAGCTTTGTG 15 V_SRF_C_M00215 TRANSFAC + 3309551 3309565 6.0E-06 ACCTTATTTGGGGTG 15 V_ETS_Q4_M00771 TRANSFAC + 3308193 3308204 6.0E-06 AAACACTTCCTC 12 V_ELF4_04_M02850 TRANSFAC + 3310061 3310077 5.0E-06 GTATTTAAAAAAAAAAA 17 V_ELF4_04_M02850 TRANSFAC + 3310062 3310078 1.0E-06 TATTTAAAAAAAAAAAA 17 V_ELF4_04_M02850 TRANSFAC + 3310063 3310079 0.0E+00 ATTTAAAAAAAAAAAAA 17 V_ELF4_04_M02850 TRANSFAC + 3310064 3310080 1.0E-06 TTTAAAAAAAAAAAAAG 17 V_ELF4_04_M02850 TRANSFAC + 3310065 3310081 1.0E-06 TTAAAAAAAAAAAAAGT 17 V_ELF4_04_M02850 TRANSFAC + 3310066 3310082 8.0E-06 TAAAAAAAAAAAAAGTC 17 V_TAL1_Q6_M00993 TRANSFAC - 3306559 3306568 7.0E-06 ACCATCTGCT 10 V_TAL1_Q6_M00993 TRANSFAC - 3309154 3309163 7.0E-06 TCCATCTGGT 10 V_BACH1_01_M00495 TRANSFAC - 3307263 3307277 4.0E-06 CAGATGAGTCAGGCT 15 V_CEBPE_Q6_M01868 TRANSFAC - 3309302 3309315 6.0E-06 CGCAATTGCAAAAT 14 V_CEBPE_Q6_M01868 TRANSFAC + 3310014 3310027 3.0E-06 CGAGATTGCATCAC 14 V_ZFP105_03_M02827 TRANSFAC + 3310063 3310077 2.0E-06 ATTTAAAAAAAAAAA 15 V_ZFP105_03_M02827 TRANSFAC + 3310064 3310078 0.0E+00 TTTAAAAAAAAAAAA 15 V_ZFP105_03_M02827 TRANSFAC + 3310065 3310079 0.0E+00 TTAAAAAAAAAAAAA 15 V_ZFP105_03_M02827 TRANSFAC + 3310066 3310080 0.0E+00 TAAAAAAAAAAAAAG 15 V_ZFP105_03_M02827 TRANSFAC + 3310067 3310081 2.0E-06 AAAAAAAAAAAAAGT 15 V_ZFP105_03_M02827 TRANSFAC + 3310068 3310082 5.0E-06 AAAAAAAAAAAAGTC 15 V_BEL1_B_M00312 TRANSFAC + 3307948 3307975 0.0E+00 AAGTAGCTGAGACTACAGGTGCATTCCA 28 V_SIX1_01_M01313 TRANSFAC + 3309075 3309091 1.0E-06 AATGGGGTATCACTGGG 17 V_HNF1_Q6_M00790 TRANSFAC + 3309488 3309505 5.0E-06 TGTTTAATAATCAAAGTG 18 V_SOX8_04_M02912 TRANSFAC + 3307331 3307344 8.0E-06 ACATTCATTGAACA 14 V_NKX31_02_M02782 TRANSFAC - 3309479 3309495 2.0E-06 ATTAAACACTTAAATGA 17 V_CEBPD_Q6_M00621 TRANSFAC + 3310017 3310028 4.0E-06 GATTGCATCACT 12 V_HSF1_01_M00146 TRANSFAC - 3307339 3307348 7.0E-06 AGAATGTTCA 10 V_CEBPB_02_M00117 TRANSFAC + 3308919 3308932 6.0E-06 TGATTGCACCACTG 14 V_CEBPB_02_M00117 TRANSFAC + 3310016 3310029 5.0E-06 AGATTGCATCACTG 14 V_SIX3_01_M01358 TRANSFAC + 3309075 3309091 0.0E+00 AATGGGGTATCACTGGG 17 V_HOXB6_01_M01460 TRANSFAC + 3309302 3309317 9.0E-06 ATTTTGCAATTGCGGT 16 V_CDX2_01_M01449 TRANSFAC - 3309457 3309472 9.0E-06 AAGGGCAATAATTCTA 16 V_SFPI1_04_M02896 TRANSFAC - 3309430 3309443 1.0E-05 AAATTACTGGAACC 14 V_HOX13_01_M00023 TRANSFAC - 3309425 3309454 6.0E-06 TTCACTGTGAGAAATTACTGGAACCCCTCC 30 V_OCT1_04_M00138 TRANSFAC + 3310055 3310077 8.0E-06 GATTCCGTATTTAAAAAAAAAAA 23 V_HBP1_03_M02762 TRANSFAC - 3307330 3307345 1.0E-06 ATGTTCAATGAATGTG 16 V_AP1_C_M00199 TRANSFAC - 3307266 3307274 3.0E-06 ATGAGTCAG 9 V_NKX3A_01_M00451 TRANSFAC + 3309481 3309492 7.0E-06 ATTTAAGTGTTT 12 V_NCX_02_M01420 TRANSFAC + 3309484 3309500 5.0E-06 TAAGTGTTTAATAATCA 17 V_SRF_Q5_02_M01007 TRANSFAC + 3309547 3309565 7.0E-06 TGTGACCTTATTTGGGGTG 19 V_ARID3A_04_M02735 TRANSFAC + 3310061 3310077 7.0E-06 GTATTTAAAAAAAAAAA 17 V_SP3_Q3_M00665 TRANSFAC + 3309260 3309273 0.0E+00 AGAATTGGGCAGGG 14 V_TBP_06_M02814 TRANSFAC + 3310060 3310075 1.0E-05 CGTATTTAAAAAAAAA 16 V_TBP_06_M02814 TRANSFAC - 3310062 3310077 3.0E-06 TTTTTTTTTTTAAATA 16 V_SIX2_01_M01433 TRANSFAC + 3309075 3309091 0.0E+00 AATGGGGTATCACTGGG 17 V_NKX23_01_M01457 TRANSFAC + 3309481 3309496 8.0E-06 ATTTAAGTGTTTAATA 16 V_HNF4A_02_M02868 TRANSFAC - 3309380 3309395 4.0E-06 CTAGAAAGTCCAAAGT 16 V_SOX17_04_M02904 TRANSFAC + 3307327 3307343 3.0E-06 GTGCACATTCATTGAAC 17 V_NKX32_02_M01482 TRANSFAC - 3309479 3309495 3.0E-06 ATTAAACACTTAAATGA 17 V_TAL1BETAITF2_01_M00070 TRANSFAC + 3306556 3306571 7.0E-06 GACAGCAGATGGTCAC 16 V_HFH8_01_M00294 TRANSFAC - 3308188 3308200 3.0E-06 AAGTGTTTATAAA 13 V_CREBP1CJUN_01_M00041 TRANSFAC - 3309474 3309481 1.0E-05 TGACGTTA 8 V_MYOD_Q6_02_M02100 TRANSFAC + 3306613 3306621 8.0E-06 CAGCTGTCT 9 V_MTF1_06_M02882 TRANSFAC + 3310062 3310075 6.0E-06 TATTTAAAAAAAAA 14 V_MTF1_06_M02882 TRANSFAC + 3310063 3310076 0.0E+00 ATTTAAAAAAAAAA 14 V_MTF1_06_M02882 TRANSFAC + 3310066 3310079 4.0E-06 TAAAAAAAAAAAAA 14 V_MTF1_06_M02882 TRANSFAC + 3310067 3310080 1.0E-06 AAAAAAAAAAAAAG 14 V_T3R_01_M00239 TRANSFAC - 3309544 3309559 3.0E-06 AAATAAGGTCACACAT 16 V_GABPBETA_Q3_M01876 TRANSFAC + 3306695 3306705 7.0E-06 ACAGGAAATGC 11 V_CEBPA_01_M00116 TRANSFAC - 3309300 3309313 2.0E-06 CAATTGCAAAATAT 14 V_TAL1ALPHAE47_01_M00066 TRANSFAC + 3306556 3306571 4.0E-06 GACAGCAGATGGTCAC 16 V_NKX3A_02_M01383 TRANSFAC - 3309480 3309496 4.0E-06 TATTAAACACTTAAATG 17 V_TCF7_04_M02921 TRANSFAC + 3310059 3310073 4.0E-06 CCGTATTTAAAAAAA 15 V_SMAD3_03_M02794 TRANSFAC - 3306612 3306628 1.0E-05 AGAAGCCAGACAGCTGG 17 V_NKX22_01_M00485 TRANSFAC + 3309483 3309492 2.0E-06 TTAAGTGTTT 10 V_SRF_01_M00152 TRANSFAC + 3309548 3309565 1.0E-06 GTGACCTTATTTGGGGTG 18 V_PITX2_Q2_M00482 TRANSFAC + 3309945 3309955 1.0E-06 TGTAATCCCAG 11 V_REST_02_M02256 TRANSFAC - 3306576 3306596 1.0E-06 CTCAGCACCATGGCTAAGACC 21 V_CEBPB_Q6_M01896 TRANSFAC + 3306674 3306683 4.0E-06 TTGTGAAATA 10 V_SRF_Q5_01_M00922 TRANSFAC - 3309547 3309561 5.0E-06 CCAAATAAGGTCACA 15 V_SRF_Q4_M00810 TRANSFAC - 3309545 3309562 2.0E-06 CCCAAATAAGGTCACACA 18 V_BBX_03_M02739 TRANSFAC + 3307331 3307345 1.0E-06 ACATTCATTGAACAT 15 V_BBX_03_M02739 TRANSFAC - 3307331 3307345 4.0E-06 ATGTTCAATGAATGT 15 V_SRF_02_M01257 TRANSFAC - 3309546 3309563 2.0E-06 CCCCAAATAAGGTCACAC 18 V_DMRT2_01_M01147 TRANSFAC + 3309271 3309286 3.0E-06 GGGAATGATACTTTCT 16 V_SRF_06_M02916 TRANSFAC + 3310061 3310077 1.0E-06 GTATTTAAAAAAAAAAA 17 V_SRF_06_M02916 TRANSFAC + 3310062 3310078 1.0E-06 TATTTAAAAAAAAAAAA 17 V_SRF_06_M02916 TRANSFAC + 3310063 3310079 0.0E+00 ATTTAAAAAAAAAAAAA 17 V_SRF_06_M02916 TRANSFAC + 3310064 3310080 0.0E+00 TTTAAAAAAAAAAAAAG 17 V_SRF_06_M02916 TRANSFAC + 3310065 3310081 0.0E+00 TTAAAAAAAAAAAAAGT 17 V_SRF_06_M02916 TRANSFAC + 3310066 3310082 0.0E+00 TAAAAAAAAAAAAAGTC 17 V_SRF_06_M02916 TRANSFAC + 3310067 3310083 1.0E-06 AAAAAAAAAAAAAGTCT 17 V_HSF2_02_M01244 TRANSFAC + 3307340 3307352 2.0E-06 GAACATTCTAGAC 13 V_NFE2_Q6_M02104 TRANSFAC + 3307265 3307280 5.0E-06 CCTGACTCATCTGTTC 16 V_SOX2_Q6_M01272 TRANSFAC + 3309412 3309427 4.0E-06 AAAGCTTTTGTTTGGA 16 V_SOX15_04_M02903 TRANSFAC - 3309472 3309486 3.0E-06 TTAAATGACGTTAGA 15 V_HOXA7_03_M01394 TRANSFAC - 3309432 3309447 3.0E-06 TGAGAAATTACTGGAA 16 V_NFE2L2_01_M02263 TRANSFAC + 3308946 3308956 2.0E-06 GTGACACAGCA 11 V_FOXO4_01_M00472 TRANSFAC + 3308191 3308201 8.0E-06 ATAAACACTTC 11 V_CEBP_Q2_01_M00912 TRANSFAC - 3309300 3309311 1.0E-06 ATTGCAAAATAT 12 V_CEBP_Q2_01_M00912 TRANSFAC + 3310082 3310093 6.0E-06 CTTTCACAATTA 12 V_TCF11MAFG_01_M00284 TRANSFAC + 3308941 3308962 4.0E-06 CCTGGGTGACACAGCAAGACAC 22 V_ZID_01_M00085 TRANSFAC - 3307363 3307375 1.0E-05 TAGCTCCAGCATC 13 V_CEBPE_01_M01772 TRANSFAC + 3309302 3309311 8.0E-06 ATTTTGCAAT 10 V_FEV_01_M02269 TRANSFAC + 3306696 3306703 1.0E-05 CAGGAAAT 8 V_GLIS2_04_M02863 TRANSFAC - 3309488 3309501 4.0E-06 TTGATTATTAAACA 14 V_ARID5A_04_M02840 TRANSFAC - 3310054 3310070 2.0E-06 TTTTAAATACGGAATCT 17 V_CEBPA_Q6_M01866 TRANSFAC + 3309300 3309312 0.0E+00 ATATTTTGCAATT 13 V_NANOG_02_M01247 TRANSFAC + 3310064 3310083 4.0E-06 TTTAAAAAAAAAAAAAGTCT 20 V_OCT4_01_M01125 TRANSFAC - 3310063 3310077 6.0E-06 TTTTTTTTTTTAAAT 15 V_HSF1_Q6_01_M02017 TRANSFAC + 3307340 3307353 1.0E-06 GAACATTCTAGACA 14

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.