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MCC Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 4163 mutated in colorectal cancers chr5 - 112824027 - 112829527 112824527 Transcription Factor Binding Sites   Download all TFBS in the MCC promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints POU4F2_POU_full_monomeric_16_1 SELEX - 112825732 112825747 4.0E-06 CTGCATAACAAATCAC 16 NFE2_bZIP_DBD_dimeric_11_1 SELEX + 112825226 112825236 1.0E-06 AATGACTCATT 11 NFE2_bZIP_DBD_dimeric_11_1 SELEX - 112825226 112825236 2.0E-06 AATGAGTCATT 11 HOXD12_homeodomain_DBD_monomeric_9_1 SELEX - 112824903 112824911 5.0E-06 ATAATAAAA 9 Foxa2_MA0047.2 JASPAR - 112824547 112824558 5.0E-06 TGTTTATATAGC 12 MYF6_bHLH_full_dimeric_10_1 SELEX + 112825027 112825036 1.0E-06 AACAACTGTT 10 MYF6_bHLH_full_dimeric_10_1 SELEX - 112825027 112825036 3.0E-06 AACAGTTGTT 10 PKNOX1_MEIS_DBD_dimeric_12_1 SELEX + 112824674 112824685 4.0E-06 TGACACCTGTCA 12 PKNOX1_MEIS_DBD_dimeric_12_1 SELEX - 112824674 112824685 0.0E+00 TGACAGGTGTCA 12 TBR1_TBX_DBD_monomeric_10_1 SELEX - 112824672 112824681 9.0E-06 AGGTGTCAAA 10 FOXC2_forkhead_DBD_monomeric_12_1 SELEX + 112824549 112824560 5.0E-06 TATATAAACACT 12 NR2E1_nuclearreceptor_full_monomeric_9_1 SELEX - 112825379 112825387 7.0E-06 AGAAGTCAA 9 NR2F1_nuclearreceptor_DBD_monomeric_13_1 SELEX + 112823875 112823887 3.0E-06 CAGGGGTCAAGGG 13 EBF1_EBF_full_dimeric_14_1 SELEX + 112825429 112825442 8.0E-06 TCTCCCTTGGGACA 14 TBX1_TBX_DBD_dimeric_23_1 SELEX - 112825006 112825028 5.0E-06 TTGAGCACTTACTAGGTGTCAGA 23 TBP_MA0108.2 JASPAR + 112824967 112824981 5.0E-06 ATATAAAAGGAGAGC 15 NFYA_MA0060.1 JASPAR + 112824630 112824645 8.0E-06 AGCCACCAATGAGAAC 16 Pknox2_MEIS_DBD_dimeric_12_1 SELEX + 112824674 112824685 3.0E-06 TGACACCTGTCA 12 Pknox2_MEIS_DBD_dimeric_12_1 SELEX - 112824674 112824685 0.0E+00 TGACAGGTGTCA 12 TGIF2_MEIS_DBD_dimeric_12_1 SELEX + 112824674 112824685 1.0E-06 TGACACCTGTCA 12 TGIF2_MEIS_DBD_dimeric_12_1 SELEX - 112824674 112824685 0.0E+00 TGACAGGTGTCA 12 TFAP2B_TFAP_DBD_dimeric_12_1 SELEX - 112826518 112826529 6.0E-06 AGCCCTCAGGCA 12 RUNX3_RUNX_full_monomeric_10_1 SELEX - 112825212 112825221 1.0E-06 AAACCACAAA 10 Tcfcp2l1_MA0145.1 JASPAR - 112825357 112825370 9.0E-06 CAAGTCCAATCCAG 14 Meis3_MEIS_DBD_dimeric_12_1 SELEX + 112824674 112824685 5.0E-06 TGACACCTGTCA 12 Meis3_MEIS_DBD_dimeric_12_1 SELEX - 112824674 112824685 0.0E+00 TGACAGGTGTCA 12 HOXD11_homeodomain_DBD_monomeric_10_2 SELEX - 112824903 112824912 1.0E-06 GATAATAAAA 10 RUNX2_RUNX_DBD_monomeric_9_1 SELEX - 112825213 112825221 8.0E-06 AAACCACAA 9 ONECUT1_CUT_full_monomeric_14_1 SELEX + 112823372 112823385 1.0E-06 TTTAAATCAATACT 14 HOXC12_homeodomain_DBD_monomeric_9_1 SELEX - 112824903 112824911 3.0E-06 ATAATAAAA 9 SP1_MA0079.2 JASPAR - 112824326 112824335 9.0E-06 CCCCTCCTCC 10 ONECUT2_CUT_DBD_monomeric_14_1 SELEX + 112823372 112823385 2.0E-06 TTTAAATCAATACT 14 FOXI1_MA0042.1 JASPAR - 112824550 112824561 7.0E-06 GAGTGTTTATAT 12 Tcf21_bHLH_DBD_dimeric_14_1 SELEX - 112825025 112825038 8.0E-06 CTAACAGTTGTTGA 14 Tcf21_bHLH_DBD_dimeric_14_1 SELEX + 112825547 112825560 3.0E-06 GCTACAGCTGTTCT 14 Tcf21_bHLH_DBD_dimeric_14_1 SELEX - 112825547 112825560 3.0E-06 AGAACAGCTGTAGC 14 TBX2_TBX_full_monomeric_11_1 SELEX - 112824672 112824682 9.0E-06 CAGGTGTCAAA 11 ID4_bHLH_DBD_dimeric_10_1 SELEX + 112824675 112824684 6.0E-06 GACACCTGTC 10 TGIF2LX_MEIS_full_dimeric_12_1 SELEX + 112824674 112824685 2.0E-06 TGACACCTGTCA 12 TGIF2LX_MEIS_full_dimeric_12_1 SELEX - 112824674 112824685 0.0E+00 TGACAGGTGTCA 12 JDP2_bZIP_full_dimeric_9_1 SELEX + 112825227 112825235 2.0E-06 ATGACTCAT 9 JDP2_bZIP_full_dimeric_9_1 SELEX - 112825227 112825235 4.0E-06 ATGAGTCAT 9 TFAP2C_TFAP_full_dimeric_12_1 SELEX - 112826518 112826529 8.0E-06 AGCCCTCAGGCA 12 Myf_MA0055.1 JASPAR - 112824026 112824037 4.0E-06 CAGCAGCAGCAG 12 Myf_MA0055.1 JASPAR - 112824029 112824040 4.0E-06 CAGCAGCAGCAG 12 Myf_MA0055.1 JASPAR - 112824032 112824043 4.0E-06 CAGCAGCAGCAG 12 Myf_MA0055.1 JASPAR - 112824035 112824046 8.0E-06 CGGCAGCAGCAG 12 Tp53_p53l_DBD_dimeric_17_1 SELEX - 112825355 112825371 7.0E-06 ACAAGTCCAATCCAGGT 17 Meis2_MEIS_DBD_dimeric_12_1 SELEX + 112824674 112824685 7.0E-06 TGACACCTGTCA 12 Meis2_MEIS_DBD_dimeric_12_1 SELEX - 112824674 112824685 0.0E+00 TGACAGGTGTCA 12 MEIS2_MEIS_DBD_dimeric_14_1 SELEX + 112824673 112824686 0.0E+00 TTGACACCTGTCAA 14 MEIS2_MEIS_DBD_dimeric_14_1 SELEX - 112824673 112824686 0.0E+00 TTGACAGGTGTCAA 14 RUNX1_MA0002.2 JASPAR - 112825195 112825205 8.0E-06 CACTGTGGTTT 11 RUNX1_MA0002.2 JASPAR + 112825211 112825221 1.0E-06 ATTTGTGGTTT 11 TFAP2A_TFAP_DBD_dimeric_12_1 SELEX - 112826518 112826529 6.0E-06 AGCCCTCAGGCA 12 RARG_nuclearreceptor_full_dimeric_16_1 SELEX - 112824665 112824680 7.0E-06 GGTGTCAAAATTTCAT 16 MSC_bHLH_full_dimeric_10_1 SELEX + 112825549 112825558 4.0E-06 TACAGCTGTT 10 CDX2_homeodomain_DBD_monomeric_9_1 SELEX - 112824903 112824911 3.0E-06 ATAATAAAA 9 Tcfap2a_TFAP_DBD_dimeric_12_1 SELEX - 112826518 112826529 8.0E-06 AGCCCTCAGGCA 12 TGIF1_MEIS_DBD_dimeric_12_1 SELEX + 112824674 112824685 1.0E-06 TGACACCTGTCA 12 TGIF1_MEIS_DBD_dimeric_12_1 SELEX - 112824674 112824685 0.0E+00 TGACAGGTGTCA 12 CDX1_homeodomain_DBD_monomeric_9_1 SELEX - 112824903 112824911 3.0E-06 ATAATAAAA 9 Irx3_homeodomain_DBD_dimeric_12_1 SELEX + 112824963 112824974 5.0E-06 TTACATATAAAA 12 ONECUT3_CUT_DBD_monomeric_14_1 SELEX + 112823372 112823385 2.0E-06 TTTAAATCAATACT 14 V_AREB6_01_M00412 TRANSFAC - 112825056 112825068 8.0E-06 TTCTTACCTGTAA 13 V_TGIF_01_M00418 TRANSFAC + 112824678 112824688 9.0E-06 ACCTGTCAAGA 11 V_AP1_Q2_M00173 TRANSFAC + 112825226 112825236 6.0E-06 AATGACTCATT 11 V_MEIS1_02_M01419 TRANSFAC + 112824674 112824689 2.0E-06 TGACACCTGTCAAGAA 16 V_DBX1_01_M01483 TRANSFAC - 112824928 112824944 2.0E-06 TTATCTATTAATACTTC 17 V_FREAC7_01_M00293 TRANSFAC + 112824547 112824562 1.0E-05 GCTATATAAACACTCT 16 V_PREP1_01_M01459 TRANSFAC + 112824674 112824689 2.0E-06 TGACACCTGTCAAGAA 16 V_AML_Q6_M00769 TRANSFAC + 112825209 112825223 8.0E-06 CAATTTGTGGTTTCG 15 V_CDX2_Q5_01_M01659 TRANSFAC - 112824659 112824669 6.0E-06 TTCATAAAAAG 11 V_EBF_Q6_M00977 TRANSFAC + 112825430 112825440 3.0E-06 CTCCCTTGGGA 11 V_OSF2_Q6_M00731 TRANSFAC - 112825212 112825219 1.0E-05 ACCACAAA 8 V_NRSF_Q4_M01028 TRANSFAC + 112824017 112824035 4.0E-06 GACGTGTCGCTGCTGCTGC 19 V_NRSF_Q4_M01028 TRANSFAC + 112824023 112824041 4.0E-06 TCGCTGCTGCTGCTGCTGC 19 V_NRSF_Q4_M01028 TRANSFAC + 112824026 112824044 4.0E-06 CTGCTGCTGCTGCTGCTGC 19 V_AML3_Q6_M01856 TRANSFAC - 112825213 112825220 1.0E-05 AACCACAA 8 V_MEF2_02_M00231 TRANSFAC + 112824924 112824945 5.0E-06 TTAGGAAGTATTAATAGATAAG 22 V_EOMES_03_M02747 TRANSFAC - 112824669 112824685 2.0E-06 TGACAGGTGTCAAAATT 17 V_CEBP_Q2_M00190 TRANSFAC - 112824660 112824673 7.0E-06 AAATTTCATAAAAA 14 V_SP1_03_M02281 TRANSFAC - 112824326 112824335 9.0E-06 CCCCTCCTCC 10 V_GATA_C_M00203 TRANSFAC + 112824939 112824949 7.0E-06 AGATAAGTACC 11 V_HFH4_01_M00742 TRANSFAC - 112824549 112824561 7.0E-06 GAGTGTTTATATA 13 V_PITX2_Q6_M02114 TRANSFAC + 112824588 112824597 1.0E-06 TGTAATCCCA 10 V_AP4_Q6_02_M01860 TRANSFAC - 112824146 112824158 2.0E-06 CCAGCTGCGGTCG 13 V_SOX21_03_M02803 TRANSFAC - 112824900 112824915 1.0E-05 ATTGATAATAAAAGAG 16 V_CDX_Q5_M00991 TRANSFAC + 112824932 112824949 8.0E-06 TATTAATAGATAAGTACC 18 V_CDX_Q5_M00991 TRANSFAC + 112826579 112826596 1.0E-05 AAATATCTAAGCAGTAAA 18 V_MEF2A_Q6_M02024 TRANSFAC - 112825286 112825295 2.0E-06 TATTTTAAAA 10 V_TGIF2_01_M01407 TRANSFAC + 112824674 112824689 9.0E-06 TGACACCTGTCAAGAA 16 V_AP1_Q6_M00174 TRANSFAC + 112825226 112825236 0.0E+00 AATGACTCATT 11 V_HNF6_Q6_M00639 TRANSFAC + 112823373 112823384 1.0E-06 TTAAATCAATAC 12 V_BACH1_01_M00495 TRANSFAC - 112825224 112825238 2.0E-06 ATAATGAGTCATTCA 15 V_SOX7_03_M02807 TRANSFAC - 112825035 112825056 9.0E-06 AATTGGGAACAATGAGAGCTAA 22 V_MEIS2_01_M01488 TRANSFAC + 112824674 112824689 1.0E-06 TGACACCTGTCAAGAA 16 V_MYF_01_M01302 TRANSFAC - 112824026 112824037 4.0E-06 CAGCAGCAGCAG 12 V_MYF_01_M01302 TRANSFAC - 112824029 112824040 4.0E-06 CAGCAGCAGCAG 12 V_MYF_01_M01302 TRANSFAC - 112824032 112824043 4.0E-06 CAGCAGCAGCAG 12 V_MYF_01_M01302 TRANSFAC - 112824035 112824046 8.0E-06 CGGCAGCAGCAG 12 V_BEL1_B_M00312 TRANSFAC + 112823939 112823966 3.0E-06 TACCTGCTGATGTATCCGTCCCCGTCGC 28 V_RUNX1_01_M02257 TRANSFAC - 112825195 112825205 8.0E-06 CACTGTGGTTT 11 V_RUNX1_01_M02257 TRANSFAC + 112825211 112825221 1.0E-06 ATTTGTGGTTT 11 V_TATA_01_M00252 TRANSFAC + 112824967 112824981 5.0E-06 ATATAAAAGGAGAGC 15 V_E12_Q6_M00693 TRANSFAC - 112824674 112824684 6.0E-06 GACAGGTGTCA 11 V_AML2_01_M01759 TRANSFAC - 112825213 112825220 1.0E-05 AACCACAA 8 V_CEBPD_Q6_M00621 TRANSFAC - 112825202 112825213 1.0E-06 AATTGCTTCACT 12 V_RSRFC4_Q2_M00407 TRANSFAC + 112824928 112824944 3.0E-06 GAAGTATTAATAGATAA 17 V_IRX4_01_M01410 TRANSFAC + 112824960 112824976 6.0E-06 ATCTTACATATAAAAGG 17 V_AP1_Q6_01_M00925 TRANSFAC + 112825227 112825235 4.0E-06 ATGACTCAT 9 V_AP1_Q4_M00188 TRANSFAC + 112825226 112825236 8.0E-06 AATGACTCATT 11 V_IK1_01_M00086 TRANSFAC + 112825776 112825788 1.0E-06 TCTTGGGAATGTC 13 V_IRF3_Q3_M01279 TRANSFAC - 112825189 112825201 6.0E-06 GTGGTTTCCCTTT 13 V_EVI1_01_M00078 TRANSFAC + 112825389 112825404 9.0E-06 AGACTAGGTTAGAAAA 16 V_MAZ_Q6_01_M02023 TRANSFAC - 112823994 112824007 5.0E-06 CGAGGAGGAGAGGA 14 V_MAZ_Q6_01_M02023 TRANSFAC + 112824323 112824336 4.0E-06 GAGGGAGGAGGGGA 14 V_HNF3_Q6_M00791 TRANSFAC + 112824548 112824560 6.0E-06 CTATATAAACACT 13 V_SOX_Q6_M01014 TRANSFAC + 112825041 112825053 6.0E-06 CTCATTGTTCCCA 13 V_EGR1_04_M02848 TRANSFAC - 112824589 112824604 2.0E-06 TGGAGAGTGGGATTAC 16 V_ISRE_01_M00258 TRANSFAC - 112826548 112826562 6.0E-06 CAGTTTCTCTCTCTC 15 V_SFPI1_04_M02896 TRANSFAC + 112824773 112824786 4.0E-06 CAATTTCTGGAAAC 14 V_JUNDM2_04_M02876 TRANSFAC + 112825223 112825238 3.0E-06 GTGAATGACTCATTAT 16 V_JUNDM2_04_M02876 TRANSFAC - 112825224 112825239 1.0E-06 AATAATGAGTCATTCA 16 V_XBP1_02_M01770 TRANSFAC - 112824017 112824027 9.0E-06 AGCGACACGTC 11 V_REX1_03_M01744 TRANSFAC - 112824100 112824111 3.0E-06 ATGATGGCGGCC 12 V_AHR_01_M00139 TRANSFAC + 112824188 112824205 5.0E-06 CCCCGAACTTGCCTGACA 18 V_IK2_01_M00087 TRANSFAC - 112825045 112825056 8.0E-06 AATTGGGAACAA 12 V_AP1_C_M00199 TRANSFAC - 112825227 112825235 8.0E-06 ATGAGTCAT 9 V_CDC5_01_M00478 TRANSFAC + 112825285 112825296 3.0E-06 GTTTTAAAATAT 12 V_NCX_02_M01420 TRANSFAC - 112824928 112824944 3.0E-06 TTATCTATTAATACTTC 17 V_AP1_01_M00517 TRANSFAC + 112825225 112825237 4.0E-06 GAATGACTCATTA 13 V_IK3_01_M00088 TRANSFAC + 112825776 112825788 3.0E-06 TCTTGGGAATGTC 13 V_SOX9_B1_M00410 TRANSFAC - 112825040 112825053 8.0E-06 TGGGAACAATGAGA 14 V_NKX23_01_M01457 TRANSFAC - 112825015 112825030 1.0E-05 TGTTGAGCACTTACTA 16 V_TFIII_Q6_M00706 TRANSFAC + 112824322 112824330 6.0E-06 AGAGGGAGG 9 V_HFH8_01_M00294 TRANSFAC - 112824549 112824561 1.0E-06 GAGTGTTTATATA 13 V_AP1_Q4_01_M00926 TRANSFAC - 112825227 112825234 1.0E-05 TGAGTCAT 8 V_YY1_03_M02044 TRANSFAC + 112824101 112824112 4.0E-06 GCCGCCATCATG 12 V_MRG2_01_M01395 TRANSFAC + 112824674 112824689 2.0E-06 TGACACCTGTCAAGAA 16 V_NKX3A_02_M01383 TRANSFAC - 112824938 112824954 7.0E-06 TATGAGGTACTTATCTA 17 V_NKX3A_02_M01383 TRANSFAC + 112825015 112825031 6.0E-06 TAGTAAGTGCTCAACAA 17 V_ESRRA_04_M02852 TRANSFAC + 112823872 112823888 1.0E-06 GAGCAGGGGTCAAGGGC 17 V_GATA6_01_M00462 TRANSFAC + 112824937 112824946 6.0E-06 ATAGATAAGT 10 V_NFY_01_M00287 TRANSFAC + 112824630 112824645 5.0E-06 AGCCACCAATGAGAAC 16 V_FRA1_Q5_M01267 TRANSFAC - 112825227 112825234 1.0E-05 TGAGTCAT 8 V_FPM315_01_M01587 TRANSFAC + 112824323 112824334 0.0E+00 GAGGGAGGAGGG 12 V_TCF4_Q5_M00671 TRANSFAC + 112825447 112825454 1.0E-05 CCTTTGAA 8 V_FOXA2_03_M02260 TRANSFAC - 112824547 112824558 5.0E-06 TGTTTATATAGC 12 V_PITX2_Q2_M00482 TRANSFAC + 112824588 112824598 2.0E-06 TGTAATCCCAC 11 V_RSRFC4_01_M00026 TRANSFAC - 112824928 112824943 3.0E-06 TATCTATTAATACTTC 16 V_E47_01_M00002 TRANSFAC + 112824481 112824495 3.0E-06 AGGGCAGGTGTACTC 15 V_PLZF_02_M01075 TRANSFAC + 112823362 112823390 1.0E-05 GGCTACTGCGTTTAAATCAATACTGGGTG 29 V_SIX4_01_M01374 TRANSFAC + 112824669 112824685 6.0E-06 AATTTTGACACCTGTCA 17 V_SIX4_01_M01374 TRANSFAC + 112825003 112825019 1.0E-06 ATGTCTGACACCTAGTA 17 V_CEBPB_Q6_M01896 TRANSFAC + 112824663 112824672 7.0E-06 TTATGAAATT 10 V_SRF_06_M02916 TRANSFAC + 112825518 112825534 6.0E-06 ATGTAAAGAAAAAAGGA 17 V_HFH3_01_M00289 TRANSFAC - 112824549 112824561 2.0E-06 GAGTGTTTATATA 13 V_COREBINDINGFACTOR_Q6_M00722 TRANSFAC - 112825195 112825202 1.0E-05 TGTGGTTT 8 V_COREBINDINGFACTOR_Q6_M00722 TRANSFAC + 112825214 112825221 1.0E-05 TGTGGTTT 8 V_HOXD8_01_M01432 TRANSFAC - 112824928 112824944 6.0E-06 TTATCTATTAATACTTC 17 V_IPF1_Q4_01_M01013 TRANSFAC + 112825228 112825242 4.0E-06 TGACTCATTATTCTG 15 V_NFE2_01_M00037 TRANSFAC - 112825227 112825237 8.0E-06 TAATGAGTCAT 11 V_SOX12_03_M02796 TRANSFAC + 112825042 112825055 4.0E-06 TCATTGTTCCCAAT 14 V_SRY_05_M02917 TRANSFAC - 112825039 112825055 1.0E-05 ATTGGGAACAATGAGAG 17 V_FREAC4_01_M00292 TRANSFAC + 112824547 112824562 3.0E-06 GCTATATAAACACTCT 16 V_ARP1_01_M00155 TRANSFAC - 112823876 112823891 1.0E-06 CGCGCCCTTGACCCCT 16 V_FOXO4_01_M00472 TRANSFAC + 112824552 112824562 8.0E-06 ATAAACACTCT 11 V_AP2ALPHA_02_M01045 TRANSFAC + 112826516 112826530 6.0E-06 TATGCCTGAGGGCTT 15 V_NFYA_Q5_M02106 TRANSFAC + 112824632 112824645 9.0E-06 CCACCAATGAGAAC 14 V_EHF_07_M02849 TRANSFAC - 112824921 112824936 2.0E-06 TAATACTTCCTAAGTC 16 V_GLIS2_04_M02863 TRANSFAC + 112824930 112824943 3.0E-06 AGTATTAATAGATA 14 V_PAX4_04_M00380 TRANSFAC + 112823092 112823121 4.0E-06 AGAAAATGTTGCGATTGCCTTCTTCACCAC 30 V_DMRT5_01_M01150 TRANSFAC - 112823093 112823107 1.0E-05 AATCGCAACATTTTC 15

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.