Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

SH2D5 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 400745 SH2 domain containing 5 chr1 - 21058633 - 21064133 21059133 Transcription Factor Binding Sites   Download all TFBS in the SH2D5 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints TBX21_TBX_full_dimeric_16_1 SELEX + 21062440 21062455 8.0E-06 TGTGGGAAGTAACACA 16 CTCF_MA0139.1 JASPAR - 21054629 21054647 7.0E-06 TGGCCTGTGGGGGGCACTC 19 Tp53_p53l_DBD_dimeric_18_1 SELEX + 21062295 21062312 1.0E-05 ACATGTTGGTGCACATGC 18 Tp53_p53l_DBD_dimeric_18_1 SELEX - 21062295 21062312 1.0E-06 GCATGTGCACCAACATGT 18 EMX2_homeodomain_DBD_dimeric_14_1 SELEX + 21062330 21062343 8.0E-06 TGATGAGTTAATGA 14 SOX2_HMG_full_dimeric_17_1 SELEX + 21059697 21059713 8.0E-06 CATCACTTTCATTCTTT 17 NHLH1_MA0048.1 JASPAR - 21054666 21054677 8.0E-06 TAGCAGCTGCTC 12 Zfp423_MA0116.1 JASPAR + 21054538 21054552 2.0E-06 GGCCCCCAGGGTGCC 15 Zfp423_MA0116.1 JASPAR - 21054538 21054552 5.0E-06 GGCACCCTGGGGGCC 15 TBX5_TBX_DBD_dimeric_20_1 SELEX + 21062437 21062456 4.0E-06 GTGTGTGGGAAGTAACACAT 20 TBX5_TBX_DBD_dimeric_20_1 SELEX - 21062437 21062456 4.0E-06 ATGTGTTACTTCCCACACAC 20 RXRG_nuclearreceptor_full_dimeric_14_1 SELEX - 21059838 21059851 5.0E-06 AAGGTCTAATGTCA 14 NR2F6_nuclearreceptor_full_dimeric_14_1 SELEX - 21059838 21059851 8.0E-06 AAGGTCTAATGTCA 14 Mafb_bZIP_DBD_monomeric_12_1 SELEX + 21054731 21054742 4.0E-06 AAAATGATGACG 12 ZNF232_C2H2_full_monomeric_19_1 SELEX - 21062544 21062562 7.0E-06 CTGTCAAAAGTGGATGTGG 19 FOXD2_forkhead_DBD_dimeric_14_1 SELEX + 21059825 21059838 2.0E-06 AATAAATATTAGCT 14 FOXD2_forkhead_DBD_dimeric_14_1 SELEX - 21059825 21059838 0.0E+00 AGCTAATATTTATT 14 MEOX2_homeodomain_DBD_dimeric_14_1 SELEX - 21062337 21062350 3.0E-06 GTCATTGTCATTAA 14 FOXD3_forkhead_DBD_dimeric_14_1 SELEX + 21059825 21059838 8.0E-06 AATAAATATTAGCT 14 FOXD3_forkhead_DBD_dimeric_14_1 SELEX - 21059825 21059838 0.0E+00 AGCTAATATTTATT 14 TCF4_bHLH_full_dimeric_10_1 SELEX - 21062358 21062367 3.0E-06 CACACCTGTA 10 RELA_MA0107.1 JASPAR - 21059406 21059415 9.0E-06 GGGGGTTTCC 10 Ascl2_bHLH_DBD_dimeric_10_1 SELEX + 21054667 21054676 2.0E-06 AGCAGCTGCT 10 Ascl2_bHLH_DBD_dimeric_10_1 SELEX - 21054667 21054676 2.0E-06 AGCAGCTGCT 10 FOXC1_forkhead_DBD_dimeric_14_1 SELEX + 21059825 21059838 4.0E-06 AATAAATATTAGCT 14 FOXC1_forkhead_DBD_dimeric_14_1 SELEX - 21059825 21059838 2.0E-06 AGCTAATATTTATT 14 TBX4_TBX_DBD_dimeric_20_1 SELEX + 21062437 21062456 2.0E-06 GTGTGTGGGAAGTAACACAT 20 TBX4_TBX_DBD_dimeric_20_1 SELEX - 21062437 21062456 8.0E-06 ATGTGTTACTTCCCACACAC 20 HOXA13_homeodomain_full_monomeric_10_1 SELEX + 21059823 21059832 7.0E-06 CCAATAAATA 10 TBX20_TBX_full_dimeric_16_1 SELEX + 21062361 21062376 1.0E-06 AGGTGTGAGCTTGCTA 16 PAX9_PAX_DBD_monomeric_17_1 SELEX - 21059629 21059645 7.0E-06 GGCCACGCCTCACTGCT 17 MGA_TBX_DBD_dimeric_18_1 SELEX + 21062439 21062456 9.0E-06 GTGTGGGAAGTAACACAT 18 MGA_TBX_DBD_dimeric_18_1 SELEX - 21062439 21062456 7.0E-06 ATGTGTTACTTCCCACAC 18 EN1_homeodomain_full_dimeric_14_1 SELEX + 21062330 21062343 1.0E-05 TGATGAGTTAATGA 14 TBX2_TBX_full_dimeric_18_1 SELEX + 21062438 21062455 3.0E-06 TGTGTGGGAAGTAACACA 18 PRDM1_C2H2_full_monomeric-or-dimeric_15_1 SELEX - 21059699 21059713 3.0E-06 AAAGAATGAAAGTGA 15 FOXC2_forkhead_DBD_dimeric_14_1 SELEX + 21059825 21059838 6.0E-06 AATAAATATTAGCT 14 FOXC2_forkhead_DBD_dimeric_14_1 SELEX - 21059825 21059838 3.0E-06 AGCTAATATTTATT 14 ERF_ETS_DBD_monomeric_10_1 SELEX + 21059807 21059816 9.0E-06 ACAGGAAGTG 10 FEV_MA0156.1 JASPAR - 21062324 21062331 1.0E-05 CAGGAAAT 8 FOXI1_forkhead_full_dimeric_17_1 SELEX + 21062206 21062222 1.0E-06 ATGTGTACAGGAAACCC 17 HOXC13_homeodomain_DBD_monomeric_10_1 SELEX + 21059823 21059832 8.0E-06 CCAATAAATA 10 Sox3_HMG_DBD_dimeric_17_1 SELEX - 21059697 21059713 5.0E-06 AAAGAATGAAAGTGATG 17 NHLH1_bHLH_full_dimeric_10_1 SELEX + 21054667 21054676 7.0E-06 AGCAGCTGCT 10 NHLH1_bHLH_full_dimeric_10_1 SELEX - 21054667 21054676 7.0E-06 AGCAGCTGCT 10 BATF3_bZIP_DBD_dimeric_14_1 SELEX + 21054735 21054748 9.0E-06 TGATGACGTCTCTG 14 Sox1_HMG_DBD_dimeric_15_2 SELEX + 21059698 21059712 7.0E-06 ATCACTTTCATTCTT 15 HOXB13_homeodomain_DBD_monomeric_10_1 SELEX + 21059823 21059832 6.0E-06 CCAATAAATA 10 V_DMRT4_01_M01149 TRANSFAC + 21062033 21062045 2.0E-06 AATGTAACAAACT 13 V_FOXP1_01_M00987 TRANSFAC + 21059850 21059869 2.0E-06 TTACTTTTAGTCTTGATTTT 20 V_MEIS1_02_M01419 TRANSFAC + 21059831 21059846 8.0E-06 TATTAGCTGACATTAG 16 V_FLI1_Q6_M01208 TRANSFAC + 21059808 21059818 2.0E-06 CAGGAAGTGAG 11 V_HSF1_Q6_M01023 TRANSFAC + 21059170 21059186 4.0E-06 CTGCCGGGACGTTCTCA 17 V_MAFK_03_M02776 TRANSFAC + 21054729 21054743 5.0E-06 AGAAAATGATGACGT 15 V_FOXA2_04_M02749 TRANSFAC + 21061983 21061999 3.0E-06 TAAAGGTACATAAAGGT 17 V_BCL6B_03_M02740 TRANSFAC + 21057965 21057980 4.0E-06 TCCTTCTTGGAATGTT 16 V_DMRT3_01_M01148 TRANSFAC - 21062031 21062045 0.0E+00 AGTTTGTTACATTTG 15 V_HMGIY_Q3_M01010 TRANSFAC + 21059860 21059874 2.0E-06 TCTTGATTTTCTTTT 15 V_BCL6_01_M01183 TRANSFAC - 21062019 21062034 8.0E-06 TTTGATGTAAACTTTT 16 V_COE1_Q6_M01871 TRANSFAC + 21059602 21059615 6.0E-06 CCTCAGGGGATCTG 14 V_ZFP740_04_M02938 TRANSFAC + 21059407 21059423 9.0E-06 GAAACCCCCCCGGAACC 17 V_SATB1_Q3_M01723 TRANSFAC + 21061988 21062003 2.0E-06 GTACATAAAGGTATAT 16 V_RELBP52_01_M01239 TRANSFAC - 21059406 21059415 3.0E-06 GGGGGTTTCC 10 V_AP2_Q6_01_M00915 TRANSFAC - 21059536 21059548 9.0E-06 GGGCCCTCAGGCC 13 V_HOXA2_01_M01402 TRANSFAC - 21062332 21062347 7.0E-06 ATTGTCATTAACTCAT 16 V_HFH4_01_M00742 TRANSFAC + 21059892 21059904 0.0E+00 AAGGGTTTGTTTA 13 V_NERF_Q2_M00531 TRANSFAC - 21059158 21059175 5.0E-06 CGGCAGGAAGAAAGTGAG 18 V_COUPTF_Q6_M01036 TRANSFAC - 21054574 21054596 2.0E-06 CCCCCTGCCCTTTGCAGCCTCCC 23 V_ETS_Q4_M00771 TRANSFAC - 21059808 21059819 7.0E-06 CCTCACTTCCTG 12 V_ZNF219_01_M01122 TRANSFAC - 21062266 21062277 8.0E-06 CACCCCCACCCC 12 V_MEIS2_01_M01488 TRANSFAC + 21059831 21059846 7.0E-06 TATTAGCTGACATTAG 16 V_IPF1_Q4_M00436 TRANSFAC + 21062334 21062345 0.0E+00 GAGTTAATGACA 12 V_TGIF_02_M01346 TRANSFAC + 21062552 21062568 9.0E-06 ACTTTTGACAGCGCACA 17 V_FKLF_Q5_M01837 TRANSFAC + 21062272 21062281 2.0E-06 GGGGTGGGAG 10 V_HOXB13_01_M01467 TRANSFAC + 21059820 21059835 2.0E-06 CACCCAATAAATATTA 16 V_ARID5A_03_M02736 TRANSFAC - 21059823 21059836 8.0E-06 CTAATATTTATTGG 14 V_SOX8_04_M02912 TRANSFAC + 21062136 21062149 0.0E+00 ACATTCATGACAAC 14 V_KROX_Q6_M00982 TRANSFAC - 21062266 21062279 3.0E-06 CCCACCCCCACCCC 14 V_MATH1_Q2_M01716 TRANSFAC - 21062168 21062177 9.0E-06 GCACCTGGTG 10 V_ASCL2_03_M02737 TRANSFAC - 21054663 21054679 2.0E-06 CATAGCAGCTGCTCAGG 17 V_ASCL2_03_M02737 TRANSFAC + 21054664 21054680 1.0E-06 CTGAGCAGCTGCTATGT 17 V_ELF5_01_M01197 TRANSFAC - 21062323 21062333 2.0E-06 ATCAGGAAATA 11 V_HBP1_03_M02762 TRANSFAC - 21054644 21054659 2.0E-06 CCAGTGAATGAATGGC 16 V_SP1SP3_Q4_M01219 TRANSFAC + 21058929 21058939 5.0E-06 CCGCCTCCTCC 11 V_AHRARNT_02_M00237 TRANSFAC + 21058114 21058132 9.0E-06 GCGAGGTGCGTGCGTGTGC 19 V_SPIB_01_M01204 TRANSFAC - 21062377 21062393 4.0E-06 AGAAAAGGGAAGATTGA 17 V_TEL2_Q6_M00678 TRANSFAC - 21059808 21059817 4.0E-06 TCACTTCCTG 10 V_PAX8_01_M00717 TRANSFAC - 21058961 21058975 6.0E-06 GAATGAAGCGTGAGT 15 V_XFD2_01_M00268 TRANSFAC + 21059823 21059836 8.0E-06 CCAATAAATATTAG 14 V_CETS1P54_01_M00032 TRANSFAC + 21059807 21059816 9.0E-06 ACAGGAAGTG 10 V_HNF4_DR1_Q3_M00764 TRANSFAC + 21059838 21059850 9.0E-06 TGACATTAGACCT 13 V_HOXA11_01_M01378 TRANSFAC - 21062192 21062207 9.0E-06 ATAAGTCATTAATCCA 16 V_STAF_02_M00264 TRANSFAC + 21062510 21062530 3.0E-06 AGCTCCCAACAGGCCTCGCAC 21 V_TGIF1_01_M03111 TRANSFAC + 21062552 21062568 9.0E-06 ACTTTTGACAGCGCACA 17 V_IRX3_01_M01318 TRANSFAC - 21061999 21062015 5.0E-06 TTTGTACATGGAATATA 17 V_CTCF_01_M01200 TRANSFAC - 21054629 21054648 9.0E-06 ATGGCCTGTGGGGGGCACTC 20 V_IRX5_01_M01472 TRANSFAC - 21061999 21062015 8.0E-06 TTTGTACATGGAATATA 17 V_SOX17_04_M02904 TRANSFAC + 21062132 21062148 4.0E-06 TCTCACATTCATGACAA 17 V_IRX3_02_M01485 TRANSFAC - 21061999 21062015 9.0E-06 TTTGTACATGGAATATA 17 V_AML2_Q3_01_M01854 TRANSFAC + 21059434 21059444 2.0E-06 CCACACCACAG 11 V_NFYC_Q5_M02107 TRANSFAC + 21058711 21058724 1.0E-06 CACCCAATCAGCGG 14 V_GABPBETA_Q3_M01876 TRANSFAC + 21059807 21059817 1.0E-06 ACAGGAAGTGA 11 V_TAL1_01_M01591 TRANSFAC + 21062383 21062395 6.0E-06 TTCCCTTTTCTCT 13 V_TCFE2A_03_M02823 TRANSFAC + 21062166 21062182 9.0E-06 GCCACCAGGTGCAAAAC 17 V_AREB6_02_M00413 TRANSFAC - 21062357 21062368 6.0E-06 TCACACCTGTAT 12 NR1H2_RXRA_MA0115.1 JASPAR - 21059836 21059852 3.0E-06 TAAGGTCTAATGTCAGC 17 V_MEIS1_01_M00419 TRANSFAC + 21059193 21059204 6.0E-06 AACTGACAGATC 12 V_GATA3_01_M00077 TRANSFAC + 21059904 21059912 7.0E-06 AAGATAGGG 9 V_GATA3_01_M00077 TRANSFAC + 21059958 21059966 7.0E-06 AAGATAGGG 9 V_DMRT7_01_M01151 TRANSFAC - 21062029 21062042 4.0E-06 TTGTTACATTTGAT 14 V_ZABC1_01_M01306 TRANSFAC + 21059769 21059776 1.0E-05 ATTCCAAC 8 V_ETS1_B_M00339 TRANSFAC + 21059807 21059821 2.0E-06 ACAGGAAGTGAGGCA 15 V_TBX5_Q5_M01044 TRANSFAC - 21062360 21062369 3.0E-06 CTCACACCTG 10 V_IRX2_01_M01405 TRANSFAC - 21061999 21062015 8.0E-06 TTTGTACATGGAATATA 17 V_IRF1_Q6_01_M01881 TRANSFAC + 21059700 21059713 9.0E-06 CACTTTCATTCTTT 14 V_TBX22_01_M01195 TRANSFAC + 21062361 21062379 7.0E-06 AGGTGTGAGCTTGCTATCA 19 V_ZFP281_04_M02831 TRANSFAC - 21062268 21062282 1.0E-05 ACTCCCACCCCCACC 15 V_FOXJ2_01_M00422 TRANSFAC + 21059820 21059837 9.0E-06 CACCCAATAAATATTAGC 18 V_HNF1A_Q5_M02013 TRANSFAC - 21059828 21059838 7.0E-06 AGCTAATATTT 11 V_SOX2_Q6_M01272 TRANSFAC - 21062338 21062353 6.0E-06 TTAGTCATTGTCATTA 16 V_SOX15_04_M02903 TRANSFAC + 21059833 21059847 1.0E-05 TTAGCTGACATTAGA 15 V_GLI_Q2_M01037 TRANSFAC - 21058707 21058718 5.0E-06 ATTGGGTGGTGC 12 V_HOXD3_01_M01338 TRANSFAC + 21062332 21062347 6.0E-06 ATGAGTTAATGACAAT 16 V_GATA1_02_M00126 TRANSFAC + 21059901 21059914 6.0E-06 TTTAAGATAGGGTA 14 V_NFYA_Q5_M02106 TRANSFAC + 21058711 21058724 6.0E-06 CACCCAATCAGCGG 14 V_TCF11MAFG_01_M00284 TRANSFAC - 21062304 21062325 9.0E-06 ATACCATGACATGGCATGTGCA 22 V_FEV_01_M02269 TRANSFAC - 21062324 21062331 1.0E-05 CAGGAAAT 8 V_HOXB5_01_M01319 TRANSFAC - 21062332 21062347 4.0E-06 ATTGTCATTAACTCAT 16 V_DMRT5_01_M01150 TRANSFAC - 21062030 21062044 0.0E+00 GTTTGTTACATTTGA 15 V_HOX13_02_M01452 TRANSFAC - 21062332 21062347 9.0E-06 ATTGTCATTAACTCAT 16 V_AP2_Q3_M00800 TRANSFAC - 21059206 21059221 3.0E-06 GGCCCCGGGCTAAGCA 16 V_HOXC9_01_M01416 TRANSFAC - 21062192 21062207 3.0E-06 ATAAGTCATTAATCCA 16

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.