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LCT Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 3938 lactase chr2 - 136594250 - 136599750 136594750 Transcription Factor Binding Sites   Download all TFBS in the LCT promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints SOX4_HMG_DBD_dimeric_16_1 SELEX - 136597543 136597558 4.0E-06 GAGCAGTTCCTGTGTT 16 Rxrb_nuclearreceptor_DBD_dimeric_14_1 SELEX - 136597489 136597502 9.0E-06 TATGTTAAAGGTCA 14 LHX6_homeodomain_full_dimeric_16_1 SELEX + 136598421 136598436 5.0E-06 TAGTTAGGGTTAACTA 16 NR4A2_nuclearreceptor_full_monomeric_11_1 SELEX - 136597489 136597499 1.0E-06 GTTAAAGGTCA 11 NR2F6_nuclearreceptor_full_dimeric_14_1 SELEX - 136597489 136597502 1.0E-06 TATGTTAAAGGTCA 14 SOX8_HMG_full_dimeric_15_1 SELEX - 136597543 136597557 5.0E-06 AGCAGTTCCTGTGTT 15 EWSR1-FLI1_MA0149.1 JASPAR + 136593471 136593488 7.0E-06 GAAAGGAAGACAGAAAGA 18 Esrrb_MA0141.1 JASPAR - 136597489 136597500 1.0E-05 TGTTAAAGGTCA 12 STAT1_MA0137.2 JASPAR + 136597623 136597637 0.0E+00 CTTTTCCTGGAAGAC 15 STAT1_MA0137.2 JASPAR - 136597623 136597637 7.0E-06 GTCTTCCAGGAAAAG 15 IRF1_MA0050.1 JASPAR - 136598393 136598404 9.0E-06 GATAGTGAAAGT 12 Meis3_MEIS_DBD_dimeric_12_1 SELEX - 136598228 136598239 8.0E-06 TCACAGGTTTCA 12 HOXD11_homeodomain_DBD_monomeric_10_2 SELEX + 136597635 136597644 9.0E-06 GACCATAAAA 10 Esrra_nuclearreceptor_DBD_dimeric_17_1 SELEX - 136597489 136597505 0.0E+00 AAGTATGTTAAAGGTCA 17 NR2F1_nuclearreceptor_DBD_dimeric_15_1 SELEX - 136597488 136597502 2.0E-06 TATGTTAAAGGTCAC 15 CTCF_C2H2_full_monomeric_17_1 SELEX + 136597518 136597534 7.0E-06 AATGCCATCTGTTGTTA 17 NR2C2_nuclearreceptor_DBD_dimeric_14_1 SELEX - 136597489 136597502 2.0E-06 TATGTTAAAGGTCA 14 MYBL1_MYB_DBD_dimeric_17_1 SELEX - 136597611 136597627 1.0E-06 AAAAGTTATTACCGTTT 17 TEAD3_TEA_DBD_dimeric_17_1 SELEX + 136597569 136597585 6.0E-06 ACATACTGATCATAGCT 17 Stat3_MA0144.1 JASPAR - 136597625 136597634 1.0E-06 TTCCAGGAAA 10 Stat3_MA0144.1 JASPAR + 136597626 136597635 2.0E-06 TTCCTGGAAG 10 PRDM1_C2H2_full_monomeric-or-dimeric_15_1 SELEX - 136598391 136598405 0.0E+00 AGATAGTGAAAGTAA 15 RORA_1_MA0071.1 JASPAR - 136597489 136597498 7.0E-06 TTAAAGGTCA 10 Hoxa11_homeodomain_DBD_monomeric_11_1 SELEX + 136597635 136597645 9.0E-06 GACCATAAAAT 11 RXRA_nuclearreceptor_full_dimeric_14_1 SELEX - 136597489 136597502 5.0E-06 TATGTTAAAGGTCA 14 HMX1_homeodomain_DBD_monomeric_11_1 SELEX - 136593327 136593337 7.0E-06 AACAATTATAT 11 V_HOXA9_01_M01351 TRANSFAC + 136597633 136597649 2.0E-06 AAGACCATAAAATTTGG 17 V_STAT5A_Q6_M01890 TRANSFAC + 136597622 136597634 5.0E-06 ACTTTTCCTGGAA 13 V_SOX30_03_M02804 TRANSFAC - 136593326 136593341 1.0E-06 ATGAAACAATTATATA 16 V_ERR3_Q2_01_M02094 TRANSFAC - 136597487 136597499 9.0E-06 GTTAAAGGTCACA 13 V_STAT_Q6_M00777 TRANSFAC + 136597621 136597633 8.0E-06 AACTTTTCCTGGA 13 V_NR2F2_03_M02783 TRANSFAC - 136597485 136597500 1.0E-06 TGTTAAAGGTCACAAA 16 V_FOXO3A_Q1_M01137 TRANSFAC + 136598280 136598291 3.0E-06 TGAAAACAAATC 12 V_SOX11_04_M02899 TRANSFAC + 136593329 136593342 6.0E-06 ATAATTGTTTCATC 14 V_STAT5B_01_M00459 TRANSFAC + 136597623 136597637 7.0E-06 CTTTTCCTGGAAGAC 15 V_HFH4_01_M00742 TRANSFAC - 136598282 136598294 1.0E-05 CAGGATTTGTTTT 13 V_DLX2_01_M01468 TRANSFAC + 136593326 136593341 8.0E-06 TATATAATTGTTTCAT 16 V_PPAR_DR1_Q2_M00763 TRANSFAC + 136597489 136597501 5.0E-06 TGACCTTTAACAT 13 V_PSX1_01_M01435 TRANSFAC + 136597508 136597524 6.0E-06 TGATTTAATGAATGCCA 17 V_CDX_Q5_M00991 TRANSFAC + 136597596 136597613 5.0E-06 AACTGTTAGTATCATAAA 18 V_CDP_04_M01344 TRANSFAC - 136597572 136597586 2.0E-06 TAGCTATGATCAGTA 15 V_BCL6_02_M01185 TRANSFAC + 136597353 136597366 4.0E-06 TGCTTTCTACTAAT 14 V_HNF1_C_M00206 TRANSFAC - 136597508 136597524 9.0E-06 TGGCATTCATTAAATCA 17 V_PPARGRXRA_01_M02262 TRANSFAC - 136597489 136597503 3.0E-06 GTATGTTAAAGGTCA 15 V_SOX13_03_M02797 TRANSFAC - 136593327 136593342 3.0E-06 GATGAAACAATTATAT 16 V_SOX7_03_M02807 TRANSFAC - 136593323 136593344 0.0E+00 AAGATGAAACAATTATATATCA 22 V_IPF1_Q4_M00436 TRANSFAC + 136597509 136597520 4.0E-06 GATTTAATGAAT 12 V_GCM1_04_M02862 TRANSFAC + 136593393 136593409 7.0E-06 TAAGTATAGGGGAGCCG 17 V_DBX2_01_M01360 TRANSFAC + 136597507 136597522 6.0E-06 GTGATTTAATGAATGC 16 V_HOXB13_01_M01467 TRANSFAC + 136597633 136597648 6.0E-06 AAGACCATAAAATTTG 16 V_GFI1_01_M00250 TRANSFAC + 136593482 136593505 4.0E-06 AGAAAGACAATCAGTGCTTGCACA 24 V_GFI1_01_M00250 TRANSFAC - 136597497 136597520 9.0E-06 ATTCATTAAATCACAAAGTATGTT 24 V_SOX8_04_M02912 TRANSFAC - 136597509 136597522 5.0E-06 GCATTCATTAAATC 14 V_SOX8_04_M02912 TRANSFAC - 136598233 136598246 2.0E-06 ACATTCATCACAGG 14 V_CEBPB_02_M00117 TRANSFAC + 136593496 136593509 2.0E-06 TGCTTGCACAACTC 14 V_RSRFC4_Q2_M00407 TRANSFAC - 136597355 136597371 5.0E-06 AATCTATTAGTAGAAAG 17 V_RSRFC4_Q2_M00407 TRANSFAC + 136597356 136597372 4.0E-06 TTTCTACTAATAGATTT 17 V_HOXA3_07_M02869 TRANSFAC - 136597360 136597373 4.0E-06 GAAATCTATTAGTA 14 V_HOXB9_01_M01426 TRANSFAC + 136597633 136597648 1.0E-06 AAGACCATAAAATTTG 16 V_CDX2_01_M01449 TRANSFAC + 136597612 136597627 1.0E-05 AACGGTAATAACTTTT 16 V_CDX2_01_M01449 TRANSFAC + 136597632 136597647 0.0E+00 GAAGACCATAAAATTT 16 V_CDX2_Q5_M00729 TRANSFAC - 136597635 136597648 1.0E-06 CAAATTTTATGGTC 14 V_SOX18_03_M02801 TRANSFAC + 136593328 136593343 1.0E-06 TATAATTGTTTCATCT 16 V_CUX1_04_M02959 TRANSFAC - 136597572 136597586 2.0E-06 TAGCTATGATCAGTA 15 V_CDX1_01_M01373 TRANSFAC + 136597632 136597647 1.0E-06 GAAGACCATAAAATTT 16 V_TAL1BETAE47_01_M00065 TRANSFAC - 136597518 136597533 1.0E-05 AACAACAGATGGCATT 16 V_GR_Q6_M00192 TRANSFAC - 136597564 136597582 4.0E-06 TATGATCAGTATGTTCATG 19 V_MEF2_04_M00233 TRANSFAC + 136598272 136598293 2.0E-06 CTTGTTTCTGAAAACAAATCCT 22 V_DAX1_01_M01248 TRANSFAC - 136597483 136597502 5.0E-06 TATGTTAAAGGTCACAAAAG 20 V_PNR_01_M01650 TRANSFAC - 136597489 136597502 5.0E-06 TATGTTAAAGGTCA 14 V_NCX_02_M01420 TRANSFAC - 136593323 136593339 8.0E-06 GAAACAATTATATATCA 17 V_STAT4_Q5_M02117 TRANSFAC - 136597625 136597634 7.0E-06 TTCCAGGAAA 10 V_STAT3_03_M01595 TRANSFAC - 136597621 136597636 4.0E-06 TCTTCCAGGAAAAGTT 16 V_NR1B1_Q6_M02110 TRANSFAC - 136597487 136597496 3.0E-06 AAAGGTCACA 10 V_NKX63_01_M01470 TRANSFAC + 136597507 136597523 5.0E-06 GTGATTTAATGAATGCC 17 V_IRX5_01_M01472 TRANSFAC - 136593382 136593398 3.0E-06 TACTTACATGTCTTAGT 17 V_SOX17_04_M02904 TRANSFAC - 136597510 136597526 5.0E-06 GATGGCATTCATTAAAT 17 V_TAL1BETAITF2_01_M00070 TRANSFAC - 136597518 136597533 5.0E-06 AACAACAGATGGCATT 16 V_IRX3_02_M01485 TRANSFAC - 136593382 136593398 9.0E-06 TACTTACATGTCTTAGT 17 V_T3R_Q6_M00963 TRANSFAC - 136593416 136593424 7.0E-06 CCTGTCCTT 9 V_ERR1_Q2_M00511 TRANSFAC - 136597487 136597500 0.0E+00 TGTTAAAGGTCACA 14 V_NKX61_02_M01469 TRANSFAC + 136593324 136593339 4.0E-06 GATATATAATTGTTTC 16 V_GATA3_01_M00077 TRANSFAC - 136598398 136598406 1.0E-05 GAGATAGTG 9 V_DMRT7_01_M01151 TRANSFAC + 136593333 136593346 7.0E-06 TTGTTTCATCTTGT 14 V_RSRFC4_01_M00026 TRANSFAC + 136597356 136597371 8.0E-06 TTTCTACTAATAGATT 16 V_RSRFC4_01_M00026 TRANSFAC - 136597356 136597371 8.0E-06 AATCTATTAGTAGAAA 16 V_IRX2_01_M01405 TRANSFAC - 136593382 136593398 9.0E-06 TACTTACATGTCTTAGT 17 V_IRX2_01_M01405 TRANSFAC + 136593383 136593399 9.0E-06 CTAAGACATGTAAGTAT 17 V_IRF1_Q6_01_M01881 TRANSFAC + 136598392 136598405 4.0E-06 TACTTTCACTATCT 14 V_RARA_03_M02787 TRANSFAC - 136597485 136597500 1.0E-06 TGTTAAAGGTCACAAA 16 V_EWSR1FLI1_01_M02252 TRANSFAC + 136593471 136593488 7.0E-06 GAAAGGAAGACAGAAAGA 18 V_SMAD3_Q6_M00701 TRANSFAC + 136593350 136593358 3.0E-06 TGTCTGTCT 9 V_BARHL2_01_M01446 TRANSFAC - 136593326 136593341 8.0E-06 ATGAAACAATTATATA 16 V_PIT1_Q6_M00802 TRANSFAC + 136598268 136598285 1.0E-05 AATTCTTGTTTCTGAAAA 18 V_RXRLXRB_01_M01198 TRANSFAC - 136597489 136597501 1.0E-06 ATGTTAAAGGTCA 13 V_LHX5_01_M01353 TRANSFAC - 136597507 136597523 6.0E-06 GGCATTCATTAAATCAC 17 V_HOXA10_01_M01464 TRANSFAC + 136597633 136597648 6.0E-06 AAGACCATAAAATTTG 16 V_HNF4_01_M00134 TRANSFAC - 136597486 136597504 5.0E-06 AGTATGTTAAAGGTCACAA 19 V_HOXD10_01_M01375 TRANSFAC + 136597633 136597649 1.0E-06 AAGACCATAAAATTTGG 17 V_IRXB3_01_M01377 TRANSFAC - 136593382 136593398 4.0E-06 TACTTACATGTCTTAGT 17 V_IRXB3_01_M01377 TRANSFAC + 136593383 136593399 5.0E-06 CTAAGACATGTAAGTAT 17 V_STAT1_Q6_M01823 TRANSFAC - 136597625 136597634 2.0E-06 TTCCAGGAAA 10 V_STAT1_05_M01260 TRANSFAC - 136597616 136597637 1.0E-06 GTCTTCCAGGAAAAGTTATTAC 22 V_STAT1_05_M01260 TRANSFAC + 136597623 136597644 4.0E-06 CTTTTCCTGGAAGACCATAAAA 22 PPARG_RXRA_MA0065.2 JASPAR - 136597489 136597503 3.0E-06 GTATGTTAAAGGTCA 15 V_PPARA_01_M00242 TRANSFAC - 136597489 136597508 4.0E-06 ACAAAGTATGTTAAAGGTCA 20 V_TR4_03_M01782 TRANSFAC - 136597489 136597501 2.0E-06 ATGTTAAAGGTCA 13 V_NANOG_02_M01247 TRANSFAC - 136597478 136597497 8.0E-06 TAAAGGTCACAAAAGCAAAA 20

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.