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ARMS2 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 387715 age-related maculopathy susceptibility 2 chr10 + 124209178 - 124214678 124214178 Transcription Factor Binding Sites   Download all TFBS in the ARMS2 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints POU4F2_POU_full_monomeric_16_1 SELEX + 124217648 124217663 7.0E-06 GTTCATTATTCATGAA 16 POU4F2_POU_full_monomeric_16_1 SELEX - 124217649 124217664 1.0E-05 ATTCATGAATAATGAA 16 TBX20_TBX_full_monomeric_11_1 SELEX + 124209448 124209458 9.0E-06 TTGGTGTGAAG 11 FOXJ2_forkhead_DBD_dimeric_13_1 SELEX - 124215259 124215271 4.0E-06 GTAAAAAACAAAA 13 VSX2_homeodomain_DBD_monomeric_8_1 SELEX - 124215207 124215214 5.0E-06 CTAATTAT 8 HOXC13_homeodomain_DBD_monomeric_11_1 SELEX - 124215265 124215275 3.0E-06 GCTTGTAAAAA 11 ALX3_homeodomain_full_monomeric_10_1 SELEX - 124215206 124215215 2.0E-06 TCTAATTATA 10 POU3F3_POU_DBD_monomeric_12_1 SELEX - 124217649 124217660 3.0E-06 ATGAATAATGAA 12 FOXG1_forkhead_DBD_dimeric_17_1 SELEX - 124215252 124215268 8.0E-06 AAAAACAAAAATTAAGA 17 POU3F2_POU_DBD_monomeric_13_1 SELEX - 124217649 124217661 4.0E-06 CATGAATAATGAA 13 LHX2_homeodomain_DBD_dimeric_15_1 SELEX + 124215208 124215222 1.0E-06 TAATTAGACAAATGA 15 LHX2_homeodomain_DBD_dimeric_15_1 SELEX - 124215208 124215222 2.0E-06 TCATTTGTCTAATTA 15 TFAP2B_TFAP_DBD_dimeric_11_1 SELEX - 124215428 124215438 5.0E-06 AGCCCCAGGCA 11 HOXD13_homeodomain_DBD_monomeric_11_1 SELEX - 124215265 124215275 2.0E-06 GCTTGTAAAAA 11 Alx1_homeodomain_DBD_monomeric_10_1 SELEX - 124215206 124215215 3.0E-06 TCTAATTATA 10 EWSR1-FLI1_MA0149.1 JASPAR - 124210070 124210087 2.0E-06 GAAAGGAGGGGAGGGAGA 18 MEF2A_MADS_DBD_dimeric_12_1 SELEX + 124215204 124215215 5.0E-06 TATATAATTAGA 12 TFAP2A_TFAP_DBD_dimeric_11_1 SELEX - 124215428 124215438 6.0E-06 AGCCCCAGGCA 11 ISX_homeodomain_DBD_dimeric_13_1 SELEX - 124215207 124215219 4.0E-06 TTTGTCTAATTAT 13 POU4F3_POU_DBD_monomeric_16_1 SELEX - 124217645 124217660 5.0E-06 ATGAATAATGAACAAT 16 POU4F3_POU_DBD_monomeric_16_1 SELEX + 124217648 124217663 1.0E-06 GTTCATTATTCATGAA 16 POU4F3_POU_DBD_monomeric_16_1 SELEX - 124217649 124217664 4.0E-06 ATTCATGAATAATGAA 16 CUX1_CUT_DBD_dimeric_18_1 SELEX + 124210437 124210454 1.0E-06 ATCAAGAATGGAATCAAT 18 FOXJ3_forkhead_DBD_dimeric_14_1 SELEX - 124217647 124217660 3.0E-06 ATGAATAATGAACA 14 FOXI1_MA0042.1 JASPAR + 124212641 124212652 3.0E-06 ATGTGTTTATTT 12 FOXC2_forkhead_DBD_dimeric_11_1 SELEX - 124215258 124215268 8.0E-06 AAAAACAAAAA 11 POU1F1_POU_DBD_monomeric_17_1 SELEX - 124217647 124217663 0.0E+00 TTCATGAATAATGAACA 17 CUX2_CUT_DBD_dimeric_18_1 SELEX + 124210437 124210454 2.0E-06 ATCAAGAATGGAATCAAT 18 POU3F1_POU_DBD_monomeric_12_2 SELEX - 124217649 124217660 1.0E-06 ATGAATAATGAA 12 FEV_MA0156.1 JASPAR - 124210004 124210011 1.0E-05 CAGGAAAT 8 TFAP2C_TFAP_full_dimeric_11_1 SELEX - 124215428 124215438 6.0E-06 AGCCCCAGGCA 11 MEOX2_homeodomain_DBD_dimeric_17_1 SELEX + 124215207 124215223 3.0E-06 ATAATTAGACAAATGAG 17 HOXB13_homeodomain_DBD_monomeric_11_1 SELEX - 124215265 124215275 4.0E-06 GCTTGTAAAAA 11 Pou5f1_MA0142.1 JASPAR - 124209964 124209978 2.0E-06 GTTTGAGATGCAAAA 15 Pou5f1_MA0142.1 JASPAR + 124215510 124215524 3.0E-06 TTTTCTAAAGCAAAT 15 HOXA13_homeodomain_full_monomeric_11_1 SELEX - 124215265 124215275 3.0E-06 GCTTGTAAAAA 11 POU3F3_POU_DBD_dimeric_12_1 SELEX - 124217649 124217660 4.0E-06 ATGAATAATGAA 12 FOXC1_forkhead_DBD_dimeric_13_1 SELEX - 124215258 124215270 4.0E-06 TAAAAAACAAAAA 13 FOXL1_MA0033.1 JASPAR + 124215202 124215209 9.0E-06 TATATATA 8 FOXL1_MA0033.1 JASPAR - 124215202 124215209 9.0E-06 TATATATA 8 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 124215256 124215268 8.0E-06 AAAAACAAAAATT 13 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 124215259 124215271 8.0E-06 GTAAAAAACAAAA 13 Tcfap2a_TFAP_DBD_dimeric_11_1 SELEX - 124215428 124215438 6.0E-06 AGCCCCAGGCA 11 POU4F1_POU_DBD_monomeric_14_1 SELEX - 124217647 124217660 5.0E-06 ATGAATAATGAACA 14 POU4F1_POU_DBD_monomeric_14_1 SELEX + 124217648 124217661 2.0E-06 GTTCATTATTCATG 14 POU4F1_POU_DBD_monomeric_14_1 SELEX - 124217651 124217664 1.0E-05 ATTCATGAATAATG 14 FOXJ2_forkhead_DBD_dimeric_14_1 SELEX - 124215258 124215271 6.0E-06 GTAAAAAACAAAAA 14 V_CEBPG_Q6_M00622 TRANSFAC - 124215105 124215117 8.0E-06 TTGATGTCTAAAT 13 V_MEIS1_02_M01419 TRANSFAC + 124215397 124215412 6.0E-06 GACAAGCTGTCATTCA 16 V_PREP1_01_M01459 TRANSFAC + 124215397 124215412 8.0E-06 GACAAGCTGTCATTCA 16 V_GEN_INI_B_M00315 TRANSFAC - 124217703 124217710 1.0E-05 CCTCATTT 8 V_TCF3_01_M01594 TRANSFAC + 124215258 124215270 0.0E+00 TTTTTGTTTTTTA 13 V_POU3F3_01_M03090 TRANSFAC - 124217649 124217665 1.0E-06 TATTCATGAATAATGAA 17 V_XFD1_01_M00267 TRANSFAC - 124212640 124212653 7.0E-06 CAAATAAACACATG 14 V_ZFP410_04_M02936 TRANSFAC + 124210069 124210085 6.0E-06 TTCTCCCTCCCCTCCTT 17 V_SOX30_03_M02804 TRANSFAC - 124217639 124217654 0.0E+00 AATGAACAATGAAACA 16 V_DLX3_01_M01400 TRANSFAC + 124215202 124215218 1.0E-06 TATATATAATTAGACAA 17 V_HMGIY_Q3_M01010 TRANSFAC + 124215503 124215517 4.0E-06 CTTTTAATTTTCTAA 15 V_HP1SITEFACTOR_Q6_M00725 TRANSFAC + 124215508 124215519 2.0E-06 AATTTTCTAAAG 12 V_POU5F1_02_M02245 TRANSFAC - 124209964 124209978 2.0E-06 GTTTGAGATGCAAAA 15 V_POU5F1_02_M02245 TRANSFAC + 124215510 124215524 3.0E-06 TTTTCTAAAGCAAAT 15 V_IK_Q5_M01169 TRANSFAC - 124211274 124211283 3.0E-06 TTTGGGAGGC 10 V_SATB1_Q3_M01723 TRANSFAC - 124217645 124217660 9.0E-06 ATGAATAATGAACAAT 16 V_PROP1_01_M01294 TRANSFAC - 124215203 124215213 9.0E-06 TAATTATATAT 11 V_OCTAMER_01_M01324 TRANSFAC - 124217649 124217665 1.0E-06 TATTCATGAATAATGAA 17 V_MEIS1AHOXA9_01_M00420 TRANSFAC - 124215395 124215408 5.0E-06 TGACAGCTTGTCAA 14 V_SRY_02_M00160 TRANSFAC - 124215257 124215268 5.0E-06 AAAAACAAAAAT 12 V_FOXO3A_Q1_M01137 TRANSFAC - 124215258 124215269 4.0E-06 AAAAAACAAAAA 12 V_HNF3_Q6_01_M01012 TRANSFAC + 124215253 124215270 6.0E-06 CTTAATTTTTGTTTTTTA 18 V_FOXJ1_03_M02750 TRANSFAC - 124212638 124212653 5.0E-06 CAAATAAACACATGAG 16 V_HFH4_01_M00742 TRANSFAC + 124212641 124212653 2.0E-06 ATGTGTTTATTTG 13 V_DLX2_01_M01468 TRANSFAC + 124215204 124215219 9.0E-06 TATATAATTAGACAAA 16 V_PITX2_Q6_M02114 TRANSFAC - 124211288 124211297 1.0E-06 TGTAATCCCA 10 V_LYF1_01_M00141 TRANSFAC - 124211275 124211283 9.0E-06 TTTGGGAGG 9 V_BRN2_01_M00145 TRANSFAC - 124217648 124217663 0.0E+00 TTCATGAATAATGAAC 16 V_PAX6_02_M01391 TRANSFAC - 124215202 124215217 9.0E-06 TGTCTAATTATATATA 16 V_CDX_Q5_M00991 TRANSFAC + 124215206 124215223 8.0E-06 TATAATTAGACAAATGAG 18 V_HNF1_C_M00206 TRANSFAC - 124209932 124209948 4.0E-06 GGGTAATGCTTTTACAC 17 V_TGIF2_01_M01407 TRANSFAC + 124215397 124215412 4.0E-06 GACAAGCTGTCATTCA 16 V_ELF4_04_M02850 TRANSFAC - 124215255 124215271 4.0E-06 GTAAAAAACAAAAATTA 17 V_SOX13_03_M02797 TRANSFAC - 124215255 124215270 5.0E-06 TAAAAAACAAAAATTA 16 V_SOX7_03_M02807 TRANSFAC - 124217636 124217657 0.0E+00 AATAATGAACAATGAAACACCA 22 V_GEN_INI3_B_M00314 TRANSFAC - 124217703 124217710 1.0E-05 CCTCATTT 8 V_TGIF_02_M01346 TRANSFAC - 124215397 124215413 3.0E-06 TTGAATGACAGCTTGTC 17 V_CEBPE_Q6_M01868 TRANSFAC + 124215481 124215494 8.0E-06 AAAAATTTGATCAC 14 V_ZFP105_03_M02827 TRANSFAC - 124215254 124215268 8.0E-06 AAAAACAAAAATTAA 15 V_ZFP105_03_M02827 TRANSFAC - 124215255 124215269 0.0E+00 AAAAAACAAAAATTA 15 V_ZFP105_03_M02827 TRANSFAC - 124215258 124215272 0.0E+00 TGTAAAAAACAAAAA 15 V_SOX8_04_M02912 TRANSFAC - 124210003 124210016 8.0E-06 AAATTCAGGAAATC 14 V_SOX8_04_M02912 TRANSFAC + 124217653 124217666 6.0E-06 TTATTCATGAATAG 14 V_SOX7_04_M02911 TRANSFAC + 124215343 124215364 1.0E-05 GTTCTAAATGTGAGCGCGCTCA 22 V_SOX7_04_M02911 TRANSFAC + 124215441 124215462 2.0E-06 GTTTGAATTGTATCTGTCTGAT 22 V_NKX61_01_M00424 TRANSFAC + 124215503 124215515 7.0E-06 CTTTTAATTTTCT 13 Ddit3_Cebpa_MA0019.1 JASPAR + 124210116 124210127 3.0E-06 GGATGCAATAGC 12 V_RSRFC4_Q2_M00407 TRANSFAC + 124215198 124215214 5.0E-06 ATAGTATATATAATTAG 17 V_MAZ_Q6_01_M02023 TRANSFAC - 124210073 124210086 4.0E-06 AAAGGAGGGGAGGG 14 V_HNF3_Q6_M00791 TRANSFAC - 124215256 124215268 4.0E-06 AAAAACAAAAATT 13 V_SOX18_03_M02801 TRANSFAC + 124217641 124217656 2.0E-06 TTTCATTGTTCATTAT 16 V_TATA_C_M00216 TRANSFAC - 124209515 124209524 5.0E-06 CCTTTAAAAG 10 V_SFPI1_04_M02896 TRANSFAC - 124210004 124210017 6.0E-06 GAAATTCAGGAAAT 14 V_AR_04_M01201 TRANSFAC + 124215290 124215304 9.0E-06 GGCTCATAATGTCCT 15 V_ERR1_Q3_M01841 TRANSFAC - 124215081 124215095 2.0E-06 ACGTGACCTGTAAGG 15 V_SOX12_04_M02900 TRANSFAC + 124215209 124215224 2.0E-06 AATTAGACAAATGAGA 16 V_GRE_C_M00205 TRANSFAC + 124215290 124215305 4.0E-06 GGCTCATAATGTCCTT 16 V_NCX_02_M01420 TRANSFAC - 124215500 124215516 1.0E-06 TAGAAAATTAAAAGCAT 17 V_ISGF3G_03_M02771 TRANSFAC - 124215255 124215269 9.0E-06 AAAAAACAAAAATTA 15 V_SMAD4_Q6_M00733 TRANSFAC - 124209479 124209493 2.0E-06 GGGGGTCAGCCACAT 15 V_TBP_06_M02814 TRANSFAC + 124215198 124215213 0.0E+00 ATAGTATATATAATTA 16 V_TBP_06_M02814 TRANSFAC - 124215198 124215213 8.0E-06 TAATTATATATACTAT 16 V_TBP_06_M02814 TRANSFAC + 124215200 124215215 6.0E-06 AGTATATATAATTAGA 16 V_TBP_06_M02814 TRANSFAC - 124215200 124215215 4.0E-06 TCTAATTATATATACT 16 V_TGIF1_01_M03111 TRANSFAC - 124215397 124215413 3.0E-06 TTGAATGACAGCTTGTC 17 V_OCT4_02_M01124 TRANSFAC - 124209963 124209977 0.0E+00 TTTGAGATGCAAAAG 15 V_SOX11_03_M02795 TRANSFAC - 124215254 124215270 2.0E-06 TAAAAAACAAAAATTAA 17 V_SOX11_03_M02795 TRANSFAC - 124217639 124217655 1.0E-06 TAATGAACAATGAAACA 17 V_SOX9_B1_M00410 TRANSFAC - 124217641 124217654 1.0E-06 AATGAACAATGAAA 14 V_FOXO1_Q5_M01216 TRANSFAC - 124215260 124215268 1.0E-06 AAAAACAAA 9 V_IRF7_01_M00453 TRANSFAC - 124215499 124215516 9.0E-06 TAGAAAATTAAAAGCATG 18 V_GR_Q6_02_M01836 TRANSFAC - 124215222 124215234 7.0E-06 CTTTGTGTTCTCT 13 V_HFH8_01_M00294 TRANSFAC + 124212641 124212653 1.0E-06 ATGTGTTTATTTG 13 V_DLX7_01_M01486 TRANSFAC + 124215202 124215218 4.0E-06 TATATATAATTAGACAA 17 V_SOX15_03_M02799 TRANSFAC - 124217639 124217655 6.0E-06 TAATGAACAATGAAACA 17 V_AP3_Q6_M00690 TRANSFAC - 124215104 124215111 5.0E-06 TCTAAATT 8 V_MRG2_01_M01395 TRANSFAC + 124215397 124215412 6.0E-06 GACAAGCTGTCATTCA 16 V_FAC1_01_M00456 TRANSFAC - 124215258 124215271 5.0E-06 GTAAAAAACAAAAA 14 V_IPF1_05_M01255 TRANSFAC - 124215503 124215514 9.0E-06 GAAAATTAAAAG 12 V_LUN1_01_M00480 TRANSFAC - 124210007 124210023 5.0E-06 TCCGAGGAAATTCAGGA 17 V_GEN_INI2_B_M00313 TRANSFAC - 124217703 124217710 1.0E-05 CCTCATTT 8 V_STAT1STAT1_Q3_M01212 TRANSFAC + 124210174 124210186 8.0E-06 CTTTAAAGGAAGA 13 V_PITX2_Q2_M00482 TRANSFAC - 124211287 124211297 1.0E-06 TGTAATCCCAG 11 V_STAT6_02_M00500 TRANSFAC + 124209957 124209964 1.0E-05 GATTTCCT 8 V_STAT6_02_M00500 TRANSFAC + 124210003 124210010 1.0E-05 GATTTCCT 8 V_NFAT2_02_M01749 TRANSFAC - 124210014 124210024 8.0E-06 TTCCGAGGAAA 11 V_CHX10_01_M00437 TRANSFAC + 124215205 124215218 8.0E-06 ATATAATTAGACAA 14 V_SOX8_03_M02808 TRANSFAC + 124215254 124215270 3.0E-06 TTAATTTTTGTTTTTTA 17 V_SOX8_03_M02808 TRANSFAC + 124217639 124217655 0.0E+00 TGTTTCATTGTTCATTA 17 V_DMRT2_01_M01147 TRANSFAC - 124210441 124210456 8.0E-06 GAATTGATTCCATTCT 16 V_SRF_06_M02916 TRANSFAC - 124215255 124215271 0.0E+00 GTAAAAAACAAAAATTA 17 V_SRF_06_M02916 TRANSFAC - 124215256 124215272 3.0E-06 TGTAAAAAACAAAAATT 17 V_SRF_06_M02916 TRANSFAC - 124215257 124215273 3.0E-06 TTGTAAAAAACAAAAAT 17 V_SRF_06_M02916 TRANSFAC - 124215258 124215274 2.0E-06 CTTGTAAAAAACAAAAA 17 V_SRF_06_M02916 TRANSFAC - 124215259 124215275 9.0E-06 GCTTGTAAAAAACAAAA 17 V_HFH3_01_M00289 TRANSFAC + 124212641 124212653 4.0E-06 ATGTGTTTATTTG 13 V_EWSR1FLI1_01_M02252 TRANSFAC - 124210070 124210087 2.0E-06 GAAAGGAGGGGAGGGAGA 18 V_FOXJ2_01_M00422 TRANSFAC - 124212639 124212656 8.0E-06 GCACAAATAAACACATGA 18 V_VDR_Q3_M00444 TRANSFAC - 124215237 124215251 6.0E-06 GAGGGAAGGGGTTCA 15 V_HOXD8_01_M01432 TRANSFAC - 124215500 124215516 4.0E-06 TAGAAAATTAAAAGCAT 17 V_SIX6_08_M02897 TRANSFAC + 124215198 124215214 5.0E-06 ATAGTATATATAATTAG 17 V_FOXO1_01_M00473 TRANSFAC - 124215260 124215269 2.0E-06 AAAAAACAAA 10 V_SOX2_Q6_M01272 TRANSFAC + 124215254 124215269 3.0E-06 TTAATTTTTGTTTTTT 16 V_PPARG_02_M00515 TRANSFAC + 124215286 124215308 7.0E-06 TTCTGGCTCATAATGTCCTTGAT 23 V_IRF1_01_M00062 TRANSFAC - 124215502 124215514 2.0E-06 GAAAATTAAAAGC 13 V_SOX12_03_M02796 TRANSFAC + 124210164 124210177 5.0E-06 TAATTGTTCCCTTT 14 V_SOX12_03_M02796 TRANSFAC + 124215258 124215271 8.0E-06 TTTTTGTTTTTTAC 14 V_SOX12_03_M02796 TRANSFAC + 124217643 124217656 4.0E-06 TCATTGTTCATTAT 14 V_PIT1_Q6_M00802 TRANSFAC - 124217648 124217665 2.0E-06 TATTCATGAATAATGAAC 18 V_SRY_05_M02917 TRANSFAC - 124217640 124217656 4.0E-06 ATAATGAACAATGAAAC 17 V_LHX4_01_M01421 TRANSFAC - 124215202 124215218 8.0E-06 TTGTCTAATTATATATA 17 V_HOXA10_01_M01464 TRANSFAC - 124215501 124215516 4.0E-06 TAGAAAATTAAAAGCA 16 V_FEV_01_M02269 TRANSFAC - 124210004 124210011 1.0E-05 CAGGAAAT 8 V_SMAD1_01_M01590 TRANSFAC - 124215257 124215268 7.0E-06 AAAAACAAAAAT 12 V_HOXA4_Q2_M00640 TRANSFAC + 124215207 124215214 5.0E-06 ATAATTAG 8 V_NANOG_02_M01247 TRANSFAC - 124215253 124215272 1.0E-06 TGTAAAAAACAAAAATTAAG 20 V_NANOG_02_M01247 TRANSFAC - 124217638 124217657 3.0E-06 AATAATGAACAATGAAACAC 20 V_OCT4_01_M01125 TRANSFAC - 124209964 124209978 1.0E-05 GTTTGAGATGCAAAA 15 V_OCT4_01_M01125 TRANSFAC + 124215510 124215524 1.0E-06 TTTTCTAAAGCAAAT 15 V_ER_Q6_M00191 TRANSFAC - 124215085 124215103 4.0E-06 TTAAACCAACGTGACCTGT 19

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