Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

SH2D4B Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 387694 SH2 domain containing 4B chr10 + 82292657 - 82301074 82300574 Transcription Factor Binding Sites   Download all TFBS in the SH2D4B promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints FOXB1_forkhead_DBD_dimeric_18_1 SELEX + 82299813 82299830 2.0E-06 TGCAAAAATATTTATACA 18 FOXB1_forkhead_DBD_dimeric_18_1 SELEX - 82299813 82299830 2.0E-06 TGTATAAATATTTTTGCA 18 HSF2_HSF_DBD_trimeric_13_1 SELEX - 82297416 82297428 1.0E-06 TTCCAGAACATTT 13 POU2F1_POU_DBD_dimeric_14_1 SELEX + 82299815 82299828 2.0E-06 CAAAAATATTTATA 14 POU2F1_POU_DBD_dimeric_14_1 SELEX - 82299815 82299828 9.0E-06 TATAAATATTTTTG 14 HSF1_HSF_full_trimeric_13_1 SELEX - 82297416 82297428 5.0E-06 TTCCAGAACATTT 13 FOXC2_forkhead_DBD_monomeric_12_1 SELEX - 82297327 82297338 3.0E-06 AAAGAAAACAAA 12 FOXC1_forkhead_DBD_monomeric_11_1 SELEX - 82299820 82299830 4.0E-06 TGTATAAATAT 11 STAT1_MA0137.2 JASPAR + 82295865 82295879 2.0E-06 GTCTTCCCGGAAACC 15 GATA5_GATA_DBD_monomeric_8_1 SELEX - 82297579 82297586 7.0E-06 AGATAAGA 8 GATA4_GATA_DBD_monomeric_8_1 SELEX - 82297579 82297586 7.0E-06 AGATAAGA 8 FOXD2_forkhead_DBD_dimeric_14_1 SELEX + 82299815 82299828 0.0E+00 CAAAAATATTTATA 14 FOXD2_forkhead_DBD_dimeric_14_1 SELEX - 82299815 82299828 2.0E-06 TATAAATATTTTTG 14 TFAP2B_TFAP_DBD_dimeric_12_1 SELEX + 82297375 82297386 4.0E-06 TCCCCCAAGGCA 12 IRF1_MA0050.1 JASPAR + 82295574 82295585 1.0E-06 AAAAATGAAAGC 12 FOXD3_forkhead_DBD_dimeric_14_1 SELEX + 82299815 82299828 0.0E+00 CAAAAATATTTATA 14 FOXD3_forkhead_DBD_dimeric_14_1 SELEX - 82299815 82299828 4.0E-06 TATAAATATTTTTG 14 HOXD13_homeodomain_DBD_monomeric_10_1 SELEX - 82300872 82300881 5.0E-06 CCCATAAAAT 10 HSF4_HSF_DBD_trimeric_13_1 SELEX - 82297416 82297428 1.0E-05 TTCCAGAACATTT 13 SP1_MA0079.2 JASPAR + 82295989 82295998 7.0E-06 CCCCGCCCCC 10 POU2F3_POU_DBD_dimeric_12_1 SELEX + 82299816 82299827 4.0E-06 AAAAATATTTAT 12 POU2F3_POU_DBD_dimeric_12_1 SELEX - 82299816 82299827 8.0E-06 ATAAATATTTTT 12 NFAT5_NFAT_DBD_dimeric_14_1 SELEX - 82301104 82301117 2.0E-06 ATGGAAAAACCCAA 14 FOXC1_forkhead_DBD_dimeric_14_1 SELEX + 82299815 82299828 1.0E-06 CAAAAATATTTATA 14 FOXC1_forkhead_DBD_dimeric_14_1 SELEX - 82299815 82299828 1.0E-06 TATAAATATTTTTG 14 SP1_C2H2_DBD_monomeric_11_1 SELEX + 82295988 82295998 4.0E-06 ACCCCGCCCCC 11 Gata1_MA0035.2 JASPAR - 82297578 82297588 3.0E-06 GCAGATAAGAG 11 GATA3_GATA_full_monomeric_8_1 SELEX - 82297579 82297586 7.0E-06 AGATAAGA 8 HOXA13_homeodomain_full_monomeric_10_1 SELEX - 82300872 82300881 1.0E-05 CCCATAAAAT 10 Foxd3_MA0041.1 JASPAR + 82297326 82297337 1.0E-05 TTTTGTTTTCTT 12 Stat3_MA0144.1 JASPAR - 82295867 82295876 3.0E-06 TTCCGGGAAG 10 PRDM1_C2H2_full_monomeric-or-dimeric_15_1 SELEX + 82295573 82295587 9.0E-06 GAAAAATGAAAGCAA 15 PRDM1_C2H2_full_monomeric-or-dimeric_15_1 SELEX + 82300790 82300804 6.0E-06 GAGAAGCGAAAGTAC 15 FOXC2_forkhead_DBD_dimeric_14_1 SELEX + 82299815 82299828 1.0E-06 CAAAAATATTTATA 14 FOXC2_forkhead_DBD_dimeric_14_1 SELEX - 82299815 82299828 1.0E-06 TATAAATATTTTTG 14 Hoxd9_homeodomain_DBD_monomeric_9_1 SELEX - 82300873 82300881 2.0E-06 CCCATAAAA 9 POU3F1_POU_DBD_monomeric_12_2 SELEX - 82299816 82299827 9.0E-06 ATAAATATTTTT 12 TFAP2C_TFAP_full_dimeric_12_1 SELEX + 82297375 82297386 4.0E-06 TCCCCCAAGGCA 12 POU5F1P1_POU_DBD_monomeric_12_1 SELEX + 82299816 82299827 6.0E-06 AAAAATATTTAT 12 HOXC13_homeodomain_DBD_monomeric_10_1 SELEX - 82300872 82300881 8.0E-06 CCCATAAAAT 10 SRY_HMG_DBD_dimeric_13_1 SELEX - 82297619 82297631 8.0E-06 TCAATGACACTGC 13 IRF3_IRF_full_trimeric_21_1 SELEX + 82295572 82295592 2.0E-06 TGAAAAATGAAAGCAAAATAA 21 IRF3_IRF_full_trimeric_21_1 SELEX - 82297317 82297337 7.0E-06 AAGAAAACAAAATGGAATCAG 21 TFAP2A_TFAP_DBD_dimeric_12_1 SELEX + 82297375 82297386 2.0E-06 TCCCCCAAGGCA 12 POU3F3_POU_DBD_dimeric_12_1 SELEX + 82299816 82299827 3.0E-06 AAAAATATTTAT 12 POU3F3_POU_DBD_dimeric_12_1 SELEX - 82299816 82299827 7.0E-06 ATAAATATTTTT 12 FOXC1_forkhead_DBD_dimeric_13_1 SELEX - 82297325 82297337 7.0E-06 AAGAAAACAAAAT 13 FOXB1_forkhead_DBD_monomeric_11_1 SELEX - 82299820 82299830 3.0E-06 TGTATAAATAT 11 Tcfap2a_TFAP_DBD_dimeric_12_1 SELEX + 82297375 82297386 7.0E-06 TCCCCCAAGGCA 12 NFIA_NFI_full_monomeric_10_1 SELEX + 82297410 82297419 9.0E-06 AATGCCAAAT 10 RREB1_MA0073.1 JASPAR - 82301091 82301110 2.0E-06 AACCCAAACAACAGCTAAAA 20 TEAD1_MA0090.1 JASPAR - 82301970 82301981 6.0E-06 TGCATTCCTGTG 12 HOXB13_homeodomain_DBD_monomeric_10_1 SELEX - 82300872 82300881 4.0E-06 CCCATAAAAT 10 IRF2_MA0051.1 JASPAR + 82295573 82295590 0.0E+00 GAAAAATGAAAGCAAAAT 18 FOXO1_forkhead_DBD_dimeric_14_1 SELEX - 82299814 82299827 4.0E-06 ATAAATATTTTTGC 14 V_HOXA9_01_M01351 TRANSFAC - 82300868 82300884 0.0E+00 ACACCCATAAAATTAGA 17 V_FOXP1_01_M00987 TRANSFAC + 82297322 82297341 9.0E-06 TCCATTTTGTTTTCTTTCTT 20 V_FOXP1_01_M00987 TRANSFAC + 82301045 82301064 6.0E-06 TCCTTTGGGTTTTCTGTTAT 20 V_FOXP1_01_M00987 TRANSFAC + 82301073 82301092 5.0E-06 TTCTTTGTCTTGTTCTTGTT 20 V_OSR1_03_M02784 TRANSFAC - 82302478 82302493 0.0E+00 TTTAACAGTAGCAGAA 16 V_STAT3_01_M00225 TRANSFAC - 82295862 82295882 1.0E-06 TCCGGTTTCCGGGAAGACGTG 21 V_FREAC7_01_M00293 TRANSFAC - 82299817 82299832 2.0E-06 TCTGTATAAATATTTT 16 V_TCF3_01_M01594 TRANSFAC + 82301074 82301086 4.0E-06 TCTTTGTCTTGTT 13 V_ATF5_01_M01295 TRANSFAC - 82297427 82297437 3.0E-06 TTTCTTCCTTT 11 V_XFD1_01_M00267 TRANSFAC - 82299817 82299830 2.0E-06 TGTATAAATATTTT 14 V_SOX14_05_M02902 TRANSFAC - 82297738 82297752 8.0E-06 CTGAGACAATGGGAA 15 V_ZFX_01_M01593 TRANSFAC - 82295789 82295804 7.0E-06 GGCCAGGCCTGGGGCG 16 V_BCL6_01_M01183 TRANSFAC - 82299803 82299818 1.0E-06 TTTGCAGTTAAATTTT 16 V_BCL6_01_M01183 TRANSFAC - 82299817 82299832 8.0E-06 TCTGTATAAATATTTT 16 V_FOXO4_02_M00476 TRANSFAC + 82297325 82297338 1.0E-06 ATTTTGTTTTCTTT 14 V_STAT_Q6_M00777 TRANSFAC + 82299774 82299786 0.0E+00 GACTCTTCTTGGA 13 V_MAFB_03_M02879 TRANSFAC + 82299809 82299823 0.0E+00 TAACTGCAAAAATAT 15 V_SP1_Q6_01_M00931 TRANSFAC - 82295988 82295997 7.0E-06 GGGGCGGGGT 10 V_ZTA_Q2_M00711 TRANSFAC - 82300753 82300765 1.0E-06 TCATTCTGACTCA 13 V_IRF_Q6_01_M00972 TRANSFAC + 82295574 82295584 1.0E-06 AAAAATGAAAG 11 V_IRF2_Q6_M01882 TRANSFAC + 82295572 82295587 0.0E+00 TGAAAAATGAAAGCAA 16 V_IRF2_Q6_M01882 TRANSFAC + 82300789 82300804 4.0E-06 TGAGAAGCGAAAGTAC 16 V_GLI1_Q2_M01042 TRANSFAC + 82301126 82301135 3.0E-06 GACCACCCAG 10 V_FOXO3A_Q1_M01137 TRANSFAC - 82297325 82297336 3.0E-06 AGAAAACAAAAT 12 V_P53_DECAMER_Q2_M00761 TRANSFAC + 82297554 82297563 9.0E-06 AGGCAAGTCT 10 V_AP2_Q6_01_M00915 TRANSFAC - 82300064 82300076 0.0E+00 CAGCCCCCAGGCT 13 V_HNF3_Q6_01_M01012 TRANSFAC + 82297324 82297341 6.0E-06 CATTTTGTTTTCTTTCTT 18 V_MAF_Q6_M00648 TRANSFAC - 82295381 82295396 1.0E-06 TCGAGGGAAGTGGCCA 16 V_MAF_Q6_M00648 TRANSFAC + 82297429 82297444 6.0E-06 AGGAAGAAAGTTGGCA 16 V_FOXJ1_03_M02750 TRANSFAC - 82297323 82297338 5.0E-06 AAAGAAAACAAAATGG 16 V_SP1_03_M02281 TRANSFAC + 82295989 82295998 7.0E-06 CCCCGCCCCC 10 V_SP1_02_M01303 TRANSFAC - 82295987 82295997 3.0E-06 GGGGCGGGGTG 11 V_HOXD13_01_M01404 TRANSFAC - 82300869 82300884 4.0E-06 ACACCCATAAAATTAG 16 V_NFAT2_01_M01748 TRANSFAC - 82301109 82301117 3.0E-06 ATGGAAAAA 9 V_TCFAP2E_04_M02926 TRANSFAC - 82301189 82301202 1.0E-06 TTCAGAAAAAAAAT 14 V_P53_02_M00272 TRANSFAC - 82297554 82297563 9.0E-06 AGACTTGCCT 10 V_MEF2A_Q6_M02024 TRANSFAC + 82299821 82299830 7.0E-06 TATTTATACA 10 V_TGIF2_01_M01407 TRANSFAC - 82302467 82302482 5.0E-06 CAGAAACTGTCAATCA 16 V_CP2_02_M00947 TRANSFAC + 82299672 82299686 7.0E-06 GCTGGGCTGCGCTGG 15 V_ELF4_04_M02850 TRANSFAC - 82301187 82301203 1.0E-06 CTTCAGAAAAAAAATGT 17 V_GLI3_02_M01704 TRANSFAC + 82301126 82301136 4.0E-06 GACCACCCAGT 11 V_ZIC3_01_M00450 TRANSFAC - 82301126 82301134 6.0E-06 TGGGTGGTC 9 V_PR_01_M00954 TRANSFAC + 82301068 82301094 6.0E-06 GTTGTTTCTTTGTCTTGTTCTTGTTTT 27 V_ZFP105_03_M02827 TRANSFAC - 82301063 82301077 2.0E-06 AAGAAACAACAAGAT 15 V_HOXB13_01_M01467 TRANSFAC - 82300869 82300884 2.0E-06 ACACCCATAAAATTAG 16 V_FOXO1_02_M00474 TRANSFAC + 82297325 82297338 1.0E-06 ATTTTGTTTTCTTT 14 V_ARID5A_03_M02736 TRANSFAC + 82299817 82299830 4.0E-06 AAAATATTTATACA 14 V_STAF_01_M00262 TRANSFAC - 82295425 82295446 1.0E-05 GTTGCCCAGCATGGACCTCTAC 22 V_NFAT_Q6_M00302 TRANSFAC + 82297357 82297368 1.0E-05 AGGAGGAAAAAT 12 V_SOX7_04_M02911 TRANSFAC + 82300866 82300887 7.0E-06 TTTCTAATTTTATGGGTGTTTC 22 V_IRF2_01_M00063 TRANSFAC + 82295573 82295585 1.0E-06 GAAAAATGAAAGC 13 V_IRF2_01_M00063 TRANSFAC + 82300790 82300802 3.0E-06 GAGAAGCGAAAGT 13 V_STAT1_01_M00224 TRANSFAC + 82295862 82295882 3.0E-06 CACGTCTTCCCGGAAACCGGA 21 V_STAT1_01_M00224 TRANSFAC - 82295862 82295882 1.0E-05 TCCGGTTTCCGGGAAGACGTG 21 V_ZBP89_Q4_M01816 TRANSFAC + 82297372 82297381 2.0E-06 TCCTCCCCCA 10 V_IRF4_04_M02872 TRANSFAC + 82301527 82301541 9.0E-06 ATCATTCTCGTTTAC 15 V_HOXB9_01_M01426 TRANSFAC - 82300869 82300884 1.0E-06 ACACCCATAAAATTAG 16 V_SP1_Q6_M00196 TRANSFAC - 82295987 82295999 3.0E-06 TGGGGGCGGGGTG 13 V_IRF_Q6_M00772 TRANSFAC - 82295574 82295588 0.0E+00 TTTGCTTTCATTTTT 15 V_IRF_Q6_M00772 TRANSFAC - 82300791 82300805 9.0E-06 TGTACTTTCGCTTCT 15 V_CDX2_Q5_M00729 TRANSFAC + 82299803 82299816 9.0E-06 AAAATTTAACTGCA 14 V_LXR_DR4_Q3_M00766 TRANSFAC - 82301267 82301282 8.0E-06 TGACCAGGACTAACCC 16 V_PAX6_Q2_M00979 TRANSFAC + 82295965 82295978 1.0E-05 CTGACCTGGGAGTG 14 V_OCT1_04_M00138 TRANSFAC + 82299804 82299826 2.0E-06 AAATTTAACTGCAAAAATATTTA 23 V_SOX12_04_M02900 TRANSFAC - 82301071 82301086 1.0E-06 AACAAGACAAAGAAAC 16 V_AHRARNT_02_M00237 TRANSFAC + 82295494 82295512 6.0E-06 CATTGTTGCGTGCGTGGGC 19 V_ZIC3_05_M02941 TRANSFAC + 82299587 82299601 2.0E-06 AGACACAGCAGGACC 15 V_GATA1_09_M02254 TRANSFAC - 82297578 82297588 3.0E-06 GCAGATAAGAG 11 V_TEF_01_M01305 TRANSFAC - 82301970 82301981 6.0E-06 TGCATTCCTGTG 12 V_PBX1_05_M01967 TRANSFAC + 82302465 82302478 1.0E-06 CTTGATTGACAGTT 14 V_AP1_C_M00199 TRANSFAC + 82300752 82300760 3.0E-06 ATGAGTCAG 9 V_KLF7_03_M02773 TRANSFAC + 82295985 82296000 9.0E-06 ATCACCCCGCCCCCAG 16 V_XFD2_01_M00268 TRANSFAC - 82299817 82299830 4.0E-06 TGTATAAATATTTT 14 V_ZIC1_01_M00448 TRANSFAC - 82301126 82301134 6.0E-06 TGGGTGGTC 9 V_ISGF3G_03_M02771 TRANSFAC + 82295573 82295587 5.0E-06 GAAAAATGAAAGCAA 15 V_AP1_01_M00517 TRANSFAC + 82300750 82300762 0.0E+00 GAATGAGTCAGAA 13 V_SP1_01_M00008 TRANSFAC - 82295988 82295997 3.0E-06 GGGGCGGGGT 10 V_TBP_06_M02814 TRANSFAC - 82299817 82299832 4.0E-06 TCTGTATAAATATTTT 16 V_STAT3_03_M01595 TRANSFAC - 82295863 82295878 2.0E-06 GTTTCCGGGAAGACGT 16 V_ICSBP_Q6_M00699 TRANSFAC + 82295575 82295586 3.0E-06 AAAATGAAAGCA 12 V_ICSBP_Q6_M00699 TRANSFAC + 82300792 82300803 5.0E-06 GAAGCGAAAGTA 12 V_FOXO1_Q5_M01216 TRANSFAC - 82297327 82297335 5.0E-06 GAAAACAAA 9 V_EVI1_06_M00011 TRANSFAC - 82301061 82301069 2.0E-06 ACAAGATAA 9 V_HOXD9_Q2_M01834 TRANSFAC - 82300873 82300882 2.0E-06 ACCCATAAAA 10 V_GATA4_Q3_M00632 TRANSFAC - 82301055 82301066 2.0E-06 AGATAACAGAAA 12 V_NEUROD_02_M01288 TRANSFAC - 82299589 82299600 6.0E-06 GTCCTGCTGTGT 12 V_GLI3_01_M01596 TRANSFAC - 82301125 82301135 4.0E-06 CTGGGTGGTCA 11 V_ELF1_Q6_M00746 TRANSFAC + 82297355 82297366 5.0E-06 ATAGGAGGAAAA 12 V_HFH8_01_M00294 TRANSFAC + 82299818 82299830 4.0E-06 AAATATTTATACA 13 V_TBP_01_M00471 TRANSFAC - 82299821 82299828 4.0E-06 TATAAATA 8 V_TTF1_Q5_M02034 TRANSFAC + 82300803 82300816 3.0E-06 ACACACTTGAGAGA 14 V_GATA1_04_M00128 TRANSFAC - 82297577 82297589 6.0E-06 TGCAGATAAGAGG 13 V_FOXL1_02_M02857 TRANSFAC + 82295581 82295596 4.0E-06 AAAGCAAAATAAGACC 16 V_FOXL1_02_M02857 TRANSFAC - 82301096 82301111 5.0E-06 AAACCCAAACAACAGC 16 V_SIRT6_01_M01797 TRANSFAC - 82297579 82297586 7.0E-06 AGATAAGA 8 V_FOXL1_04_M02753 TRANSFAC - 82297324 82297340 9.0E-06 AGAAAGAAAACAAAATG 17 V_LUN1_01_M00480 TRANSFAC + 82302044 82302060 4.0E-06 TCCCAGGTTCTCAGGGC 17 V_EBNA1_01_M01745 TRANSFAC + 82302472 82302487 7.0E-06 GACAGTTTCTGCTACT 16 V_MEIS1_01_M00419 TRANSFAC + 82295414 82295425 9.0E-06 TTGTGACAGGAG 12 V_ZBTB4_04_M02929 TRANSFAC + 82299696 82299711 8.0E-06 CACTAACTGGTGAAAT 16 V_OSR2_03_M02785 TRANSFAC - 82302478 82302493 1.0E-06 TTTAACAGTAGCAGAA 16 V_FOXO3_01_M00477 TRANSFAC + 82297325 82297338 1.0E-06 ATTTTGTTTTCTTT 14 V_STAT_01_M00223 TRANSFAC + 82295868 82295876 7.0E-06 TTCCCGGAA 9 V_PBX1_02_M00124 TRANSFAC - 82302463 82302477 5.0E-06 ACTGTCAATCAAGAT 15 V_ZFP281_01_M01597 TRANSFAC - 82295989 82295999 6.0E-06 TGGGGGCGGGG 11 V_TITF1_Q3_M00432 TRANSFAC - 82300805 82300814 3.0E-06 TCTCAAGTGT 10 V_IRF1_Q6_01_M01881 TRANSFAC - 82295573 82295586 1.0E-06 TGCTTTCATTTTTC 14 V_SRF_06_M02916 TRANSFAC - 82301187 82301203 1.0E-06 CTTCAGAAAAAAAATGT 17 V_HSF2_02_M01244 TRANSFAC + 82297416 82297428 8.0E-06 AAATGTTCTGGAA 13 V_IRF1_01_M00062 TRANSFAC + 82295573 82295585 0.0E+00 GAAAAATGAAAGC 13 V_PIT1_Q6_M00802 TRANSFAC + 82299811 82299828 1.0E-06 ACTGCAAAAATATTTATA 18 V_GLI_Q2_M01037 TRANSFAC - 82301125 82301136 6.0E-06 ACTGGGTGGTCA 12 V_SP1_Q2_01_M00933 TRANSFAC + 82295989 82295998 4.0E-06 CCCCGCCCCC 10 V_GATA5_03_M02756 TRANSFAC - 82297575 82297591 4.0E-06 TCTGCAGATAAGAGGAG 17 V_ZFP128_04_M02932 TRANSFAC - 82299817 82299830 8.0E-06 TGTATAAATATTTT 14 V_SP1_Q4_01_M00932 TRANSFAC - 82295987 82295999 9.0E-06 TGGGGGCGGGGTG 13 V_TAACC_B_M00331 TRANSFAC - 82301053 82301075 3.0E-06 GAAACAACAAGATAACAGAAAAC 23 V_LTF_Q6_M01692 TRANSFAC + 82295481 82295489 1.0E-05 GTCACTTGC 9 V_STAT1_Q6_M01823 TRANSFAC - 82295867 82295876 8.0E-06 TTCCGGGAAG 10 V_ZIC2_01_M00449 TRANSFAC - 82301126 82301134 6.0E-06 TGGGTGGTC 9 V_DTYPEPA_B_M00334 TRANSFAC + 82295546 82295555 5.0E-06 AACATTAAAC 10 V_STAT1_05_M01260 TRANSFAC - 82295858 82295879 9.0E-06 GGTTTCCGGGAAGACGTGCTTC 22 V_FOXK1_03_M02752 TRANSFAC - 82297324 82297340 4.0E-06 AGAAAGAAAACAAAATG 17 V_SMAD1_01_M01590 TRANSFAC - 82301073 82301084 5.0E-06 CAAGACAAAGAA 12 V_DMRT5_01_M01150 TRANSFAC + 82301067 82301081 2.0E-06 TGTTGTTTCTTTGTC 15 V_NANOG_02_M01247 TRANSFAC - 82301069 82301088 1.0E-06 AGAACAAGACAAAGAAACAA 20

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.