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IGFBP4 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 3487 insulin-like growth factor binding protein 4 chr17 + 38594675 - 38600175 38599675 Transcription Factor Binding Sites   Download all TFBS in the IGFBP4 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints SP3_C2H2_DBD_monomeric_11_1 SELEX - 38599652 38599662 7.0E-06 GCCACACCCCC 11 SOX10_HMG_full_dimeric_14_1 SELEX + 38603718 38603731 9.0E-06 TTAATTTTTAGTCA 14 SPIC_ETS_full_monomeric_14_1 SELEX - 38601344 38601357 1.0E-06 CAAATCAGGAAGAA 14 SPIC_ETS_full_monomeric_14_1 SELEX + 38601777 38601790 2.0E-06 GAAAACAGGAAGGA 14 KLF16_C2H2_DBD_monomeric_11_1 SELEX - 38599652 38599662 4.0E-06 GCCACACCCCC 11 IRF8_IRF_full_dimeric_14_1 SELEX - 38601452 38601465 4.0E-06 CTGAAACAGAAACA 14 Mafb_bZIP_DBD_monomeric_12_1 SELEX + 38598799 38598810 1.0E-06 AAAGTGCTGACA 12 EWSR1-FLI1_MA0149.1 JASPAR - 38599779 38599796 6.0E-06 GGAGGGGAGCAAGCCTGG 18 EWSR1-FLI1_MA0149.1 JASPAR + 38601776 38601793 4.0E-06 GGAAAACAGGAAGGAGGT 18 ERG_ETS_full_dimeric_14_1 SELEX + 38604526 38604539 6.0E-06 AGAGGAAATCCTCT 14 STAT1_MA0137.2 JASPAR + 38603794 38603808 6.0E-06 GCATTCCCAGAAATT 15 EGR1_C2H2_full_monomeric_14_1 SELEX - 38599122 38599135 1.0E-06 CCCGCCCCCGCAAT 14 SPIB_ETS_DBD_monomeric_14_1 SELEX - 38601727 38601740 7.0E-06 GGATTGAGGAAGTG 14 SPIB_ETS_DBD_monomeric_14_1 SELEX + 38601777 38601790 8.0E-06 GAAAACAGGAAGGA 14 RUNX3_RUNX_full_monomeric_10_1 SELEX - 38602263 38602272 5.0E-06 CAACCACAAA 10 Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1 SELEX - 38599121 38599136 1.0E-06 TCCCGCCCCCGCAATC 16 HOXC12_homeodomain_DBD_monomeric_9_1 SELEX - 38600795 38600803 8.0E-06 GTAAAAAAA 9 TCF4_bHLH_full_dimeric_10_1 SELEX - 38598812 38598821 3.0E-06 CACACCTGTA 10 HNF1A_homeodomain_full_dimeric_15_1 SELEX - 38603716 38603730 3.0E-06 GACTAAAAATTAACC 15 HOXD8_homeodomain_DBD_monomeric_10_1 SELEX - 38603717 38603726 4.0E-06 AAAAATTAAC 10 EGR2_C2H2_full_monomeric_15_1 SELEX - 38599122 38599136 4.0E-06 TCCCGCCCCCGCAAT 15 SP1_MA0079.2 JASPAR + 38599580 38599589 3.0E-06 CCCCTCCCCC 10 HNF4A_nuclearreceptor_full_dimeric_16_1 SELEX + 38599670 38599685 6.0E-06 CGGTATAAAGTCCGGG 16 ZIC3_C2H2_full_monomeric_15_1 SELEX + 38600197 38600211 5.0E-06 CACCCCCCGTTGCGG 15 Egr3_C2H2_DBD_monomeric_15_1 SELEX - 38599121 38599135 1.0E-06 CCCGCCCCCGCAATC 15 SP1_C2H2_DBD_monomeric_11_1 SELEX - 38599652 38599662 8.0E-06 GCCACACCCCC 11 NRL_bZIP_DBD_monomeric_11_1 SELEX + 38598799 38598809 3.0E-06 AAAGTGCTGAC 11 NRL_bZIP_DBD_monomeric_11_1 SELEX - 38601857 38601867 8.0E-06 TTTCTGCTGAC 11 EGR4_C2H2_DBD_monomeric_16_2 SELEX - 38599121 38599136 2.0E-06 TCCCGCCCCCGCAATC 16 HNF1B_homeodomain_full_dimeric_13_1 SELEX + 38603717 38603729 5.0E-06 GTTAATTTTTAGT 13 IRF9_IRF_full_trimeric_15_1 SELEX - 38601452 38601466 2.0E-06 ACTGAAACAGAAACA 15 PRDM1_C2H2_full_monomeric-or-dimeric_15_1 SELEX - 38601271 38601285 6.0E-06 AAAAAAAGAAAGTGT 15 NFIB_NFI_full_dimeric_15_1 SELEX - 38604659 38604673 1.0E-05 TTGGAGCTAAGCCAG 15 SPDEF_ETS_full_putative-multimer_16_1 SELEX - 38601318 38601333 0.0E+00 AGAGAAAGAAGGAAAA 16 IRF4_IRF_full_dimeric_15_1 SELEX - 38601451 38601465 9.0E-06 CTGAAACAGAAACAC 15 Sox11_HMG_DBD_dimeric_15_1 SELEX - 38598915 38598929 1.0E-05 AACAACTCCAGTGGG 15 FOXC1_MA0032.1 JASPAR + 38597489 38597496 7.0E-06 AGTAAGTA 8 MAFK_bZIP_full_monomeric_12_1 SELEX + 38598798 38598809 1.0E-06 AAAAGTGCTGAC 12 SPI1_ETS_full_monomeric_14_1 SELEX + 38601777 38601790 7.0E-06 GAAAACAGGAAGGA 14 RUNX1_MA0002.2 JASPAR + 38602262 38602272 9.0E-06 TTTTGTGGTTG 11 IRF3_IRF_full_trimeric_21_1 SELEX - 38601451 38601471 5.0E-06 GAGCAACTGAAACAGAAACAC 21 HNF1B_homeodomain_full_dimeric_15_1 SELEX - 38603716 38603730 2.0E-06 GACTAAAAATTAACC 15 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 38601279 38601291 2.0E-06 AGAAACAAAAAAA 13 HNF1A_MA0046.1 JASPAR + 38603716 38603729 0.0E+00 GGTTAATTTTTAGT 14 ZIC1_C2H2_full_monomeric_14_1 SELEX + 38600197 38600210 2.0E-06 CACCCCCCGTTGCG 14 V_MYB_Q6_M00183 TRANSFAC + 38604654 38604663 4.0E-06 GTCAACTGGC 10 V_MEQ_01_M02049 TRANSFAC + 38601136 38601144 7.0E-06 AACACACAC 9 V_FOXP1_01_M00987 TRANSFAC - 38601135 38601154 5.0E-06 GTGTGTGTGTGTGTGTGTTT 20 V_SPI1_01_M01203 TRANSFAC - 38601724 38601740 7.0E-06 GGATTGAGGAAGTGGAG 17 V_SPI1_01_M01203 TRANSFAC + 38601777 38601793 7.0E-06 GAAAACAGGAAGGAGGT 17 V_STAT5A_Q6_M01890 TRANSFAC - 38603797 38603809 1.0E-06 GAATTTCTGGGAA 13 V_TCF3_01_M01594 TRANSFAC + 38601273 38601285 6.0E-06 ACTTTCTTTTTTT 13 V_OSF2_Q6_M00731 TRANSFAC - 38602263 38602270 1.0E-05 ACCACAAA 8 V_MAFK_03_M02776 TRANSFAC + 38598797 38598811 1.0E-06 CAAAAGTGCTGACAT 15 V_SMAD3_Q6_01_M01888 TRANSFAC - 38601550 38601562 1.0E-06 AGACAGACAGAGA 13 V_SMAD3_Q6_01_M01888 TRANSFAC - 38601621 38601633 1.0E-06 AGACAGACAGAGG 13 V_NF1_Q6_01_M00806 TRANSFAC - 38601025 38601041 4.0E-06 TCGGCTAGGAGCCAAGA 17 V_EVI1_04_M00081 TRANSFAC - 38601275 38601289 4.0E-06 AAACAAAAAAAGAAA 15 V_MAFB_05_M02775 TRANSFAC + 38598798 38598814 0.0E+00 AAAAGTGCTGACATTAC 17 V_AML3_Q6_M01856 TRANSFAC - 38602264 38602271 1.0E-05 AACCACAA 8 V_STAT_Q6_M00777 TRANSFAC - 38603798 38603810 3.0E-06 AGAATTTCTGGGA 13 V_LMAF_Q2_M01139 TRANSFAC + 38601856 38601864 6.0E-06 GGTCAGCAG 9 V_IRF_Q6_01_M00972 TRANSFAC - 38601274 38601284 5.0E-06 AAAAAAGAAAG 11 V_IRF_Q6_01_M00972 TRANSFAC - 38601453 38601463 6.0E-06 GAAACAGAAAC 11 V_IRF2_Q6_M01882 TRANSFAC - 38601271 38601286 7.0E-06 CAAAAAAAGAAAGTGT 16 V_NFAT3_Q3_M01734 TRANSFAC - 38602215 38602224 3.0E-06 TTATTTTCCT 10 V_NKX25_Q6_M02108 TRANSFAC - 38598948 38598958 1.0E-05 GCCACTTGCAA 11 V_STAT5B_01_M00459 TRANSFAC + 38603794 38603808 5.0E-06 GCATTCCCAGAAATT 15 V_STAT5B_01_M00459 TRANSFAC - 38603794 38603808 8.0E-06 AATTTCTGGGAATGC 15 V_SP1_03_M02281 TRANSFAC + 38599580 38599589 3.0E-06 CCCCTCCCCC 10 V_SPZ1_01_M00446 TRANSFAC - 38600356 38600370 1.0E-06 TCAGGAGGGAATTGG 15 V_SPZ1_01_M00446 TRANSFAC - 38601716 38601730 2.0E-06 AGTGGAGGGTTTGGG 15 V_PU1_Q4_M01172 TRANSFAC + 38601338 38601356 5.0E-06 CTTTTGTTCTTCCTGATTT 19 V_PU1_Q4_M01172 TRANSFAC + 38601721 38601739 0.0E+00 ACCCTCCACTTCCTCAATC 19 V_PU1_Q4_M01172 TRANSFAC - 38601778 38601796 3.0E-06 TCCACCTCCTTCCTGTTTT 19 V_LYF1_01_M00141 TRANSFAC + 38602352 38602360 9.0E-06 TTTGGGAGG 9 V_GM497_04_M02864 TRANSFAC + 38601133 38601148 7.0E-06 AGAAACACACACACAC 16 V_TCFAP2E_04_M02926 TRANSFAC - 38600793 38600806 5.0E-06 CATGTAAAAAAAAA 14 V_RPC155_01_M01798 TRANSFAC + 38602372 38602387 0.0E+00 CCAGGAGTTCGAGACC 16 V_ELF4_04_M02850 TRANSFAC - 38600789 38600805 1.0E-06 ATGTAAAAAAAAAGTTC 17 V_SOX7_03_M02807 TRANSFAC - 38601331 38601352 4.0E-06 CAGGAAGAACAAAAGAGCAAGA 22 V_EGR1_01_M00243 TRANSFAC + 38599123 38599134 4.0E-06 TTGCGGGGGCGG 12 V_PR_Q2_M00960 TRANSFAC - 38600981 38600990 9.0E-06 AAAAGAACAG 10 V_SPI1_03_M02078 TRANSFAC - 38601727 38601736 4.0E-06 TGAGGAAGTG 10 V_GCM1_04_M02862 TRANSFAC - 38604634 38604650 6.0E-06 TGACTATAGGGGAAACC 17 V_ZFP105_03_M02827 TRANSFAC - 38600790 38600804 2.0E-06 TGTAAAAAAAAAGTT 15 V_ZFP105_03_M02827 TRANSFAC - 38601274 38601288 9.0E-06 AACAAAAAAAGAAAG 15 V_RUNX1_01_M02257 TRANSFAC + 38602262 38602272 9.0E-06 TTTTGTGGTTG 11 V_SIX1_01_M01313 TRANSFAC + 38603892 38603908 1.0E-05 CCTCGGGTATCAGGAGT 17 V_HNF1_Q6_M00790 TRANSFAC + 38603715 38603732 3.0E-06 GGGTTAATTTTTAGTCAA 18 V_NGFIC_01_M00244 TRANSFAC + 38599123 38599134 5.0E-06 TTGCGGGGGCGG 12 V_E2F1_01_M01250 TRANSFAC + 38601428 38601435 1.0E-05 CGTTTCTT 8 V_DOBOX4_01_M01359 TRANSFAC + 38602219 38602235 7.0E-06 AAATAAGATCCCCTAGG 17 V_AML2_01_M01759 TRANSFAC - 38602264 38602271 1.0E-05 AACCACAA 8 V_AP1_Q4_M00188 TRANSFAC - 38598818 38598828 5.0E-06 AGTGACTCACA 11 V_IK1_01_M00086 TRANSFAC - 38603793 38603805 6.0E-06 TTCTGGGAATGCC 13 V_EGR1_Q6_M01873 TRANSFAC + 38599125 38599134 4.0E-06 GCGGGGGCGG 10 V_IRF_Q6_M00772 TRANSFAC + 38601270 38601284 0.0E+00 TACACTTTCTTTTTT 15 V_IRF_Q6_M00772 TRANSFAC + 38601449 38601463 9.0E-06 CTGTGTTTCTGTTTC 15 V_IRF_Q6_M00772 TRANSFAC + 38601455 38601469 9.0E-06 TTCTGTTTCAGTTGC 15 V_STAT5A_02_M00460 TRANSFAC + 38603797 38603820 0.0E+00 TTCCCAGAAATTCTGTGCCTTGTG 24 V_HNF1_Q6_01_M01011 TRANSFAC - 38603713 38603733 0.0E+00 ATTGACTAAAAATTAACCCAG 21 V_PAX5_01_M00143 TRANSFAC - 38598970 38598997 8.0E-06 TTCAGACCCACTCGTGGAGGGAGGCAGG 28 V_EGR1_04_M02848 TRANSFAC + 38600814 38600829 1.0E-06 GGTGGAGTGGGACATA 16 V_ISRE_01_M00258 TRANSFAC + 38601272 38601286 1.0E-05 CACTTTCTTTTTTTG 15 V_OCT1_04_M00138 TRANSFAC - 38600791 38600813 3.0E-06 ACTGGACCATGTAAAAAAAAAGT 23 V_ZBRK1_01_M01105 TRANSFAC - 38603738 38603752 6.0E-06 GGGGGGCAGAATTTG 15 V_MEF2_04_M00233 TRANSFAC - 38603714 38603735 1.0E-05 GCATTGACTAAAAATTAACCCA 22 V_PEBP_Q6_M00984 TRANSFAC - 38602260 38602274 6.0E-06 GACAACCACAAAATT 15 V_SPIB_01_M01204 TRANSFAC - 38601341 38601357 6.0E-06 CAAATCAGGAAGAACAA 17 V_SPIB_01_M01204 TRANSFAC + 38601777 38601793 5.0E-06 GAAAACAGGAAGGAGGT 17 V_STAF_02_M00264 TRANSFAC - 38598848 38598868 1.0E-06 ATTTCCCAGATGGCAGTGAAG 21 V_IK3_01_M00088 TRANSFAC - 38603793 38603805 2.0E-06 TTCTGGGAATGCC 13 V_SOX11_03_M02795 TRANSFAC - 38601277 38601293 6.0E-06 TGAGAAACAAAAAAAGA 17 V_SOX11_03_M02795 TRANSFAC - 38601334 38601350 3.0E-06 GGAAGAACAAAAGAGCA 17 V_ISGF4G_04_M02875 TRANSFAC - 38601392 38601405 4.0E-06 GGAAAACAGAACTC 14 V_ICSBP_Q6_M00699 TRANSFAC - 38601272 38601283 1.0E-06 AAAAAGAAAGTG 12 V_ZFP691_04_M02937 TRANSFAC + 38599382 38599398 0.0E+00 GACGAGACTCCTCCGAG 17 V_GATA4_Q3_M00632 TRANSFAC - 38601320 38601331 7.0E-06 AGAAAGAAGGAA 12 V_NEUROD_02_M01288 TRANSFAC + 38600015 38600026 6.0E-06 CTGCTGCTGGCC 12 V_ELF1_Q6_M00746 TRANSFAC - 38601728 38601739 9.0E-06 GATTGAGGAAGT 12 V_ELF1_Q6_M00746 TRANSFAC + 38604523 38604534 0.0E+00 GAAAGAGGAAAT 12 V_ZFP187_04_M02934 TRANSFAC - 38599089 38599104 7.0E-06 GGGCCCTGGTCCACCC 16 V_ZFP187_04_M02934 TRANSFAC - 38603782 38603797 1.0E-06 ATGCCCTTGTTCCCAT 16 V_MYOD_Q6_02_M02100 TRANSFAC + 38600657 38600665 8.0E-06 CAGCTGTCT 9 V_MTF1_06_M02882 TRANSFAC - 38600792 38600805 6.0E-06 ATGTAAAAAAAAAG 14 V_POU5F1_01_M01307 TRANSFAC + 38602285 38602294 9.0E-06 AATGCAAACT 10 V_GABPBETA_Q3_M01876 TRANSFAC - 38604603 38604613 1.0E-05 AGAGGAAGGGA 11 V_MYF6_04_M02885 TRANSFAC - 38600142 38600156 7.0E-06 CGCAACAGCCGCAGC 15 V_FAC1_01_M00456 TRANSFAC - 38601276 38601289 3.0E-06 AAACAAAAAAAGAA 14 V_HNF1_01_M00132 TRANSFAC + 38603716 38603730 0.0E+00 GGTTAATTTTTAGTC 15 V_AREB6_02_M00413 TRANSFAC - 38598811 38598822 6.0E-06 TCACACCTGTAA 12 V_OCT1_Q6_M00195 TRANSFAC + 38600823 38600837 2.0E-06 GGACATACAAATTAG 15 V_LUN1_01_M00480 TRANSFAC + 38601530 38601546 0.0E+00 TCCCTGTTACTTTGGGA 17 V_E2F6_01_M01252 TRANSFAC + 38601428 38601435 1.0E-05 CGTTTCTT 8 V_HDX_01_M01333 TRANSFAC + 38604503 38604519 8.0E-06 AGGGTAAAATCAGGCAA 17 V_BDP1_01_M01796 TRANSFAC - 38602376 38602387 2.0E-06 GGTCTCGAACTC 12 V_MECP2_02_M01299 TRANSFAC - 38599675 38599684 7.0E-06 CCGGACTTTA 10 V_MTATA_B_M00320 TRANSFAC + 38599670 38599686 6.0E-06 CGGTATAAAGTCCGGGG 17 V_SPIC_02_M02077 TRANSFAC - 38601727 38601736 5.0E-06 TGAGGAAGTG 10 V_STAT6_02_M00500 TRANSFAC - 38604528 38604535 1.0E-05 GATTTCCT 8 V_ETS1_B_M00339 TRANSFAC + 38601781 38601795 6.0E-06 ACAGGAAGGAGGTGG 15 V_ZFP281_01_M01597 TRANSFAC - 38599580 38599590 3.0E-06 AGGGGGAGGGG 11 V_TBX5_Q5_M01044 TRANSFAC - 38598814 38598823 3.0E-06 CTCACACCTG 10 V_EGR1_06_M02744 TRANSFAC - 38599122 38599135 0.0E+00 CCCGCCCCCGCAAT 14 V_IRF1_Q6_01_M01881 TRANSFAC + 38601272 38601285 1.0E-06 CACTTTCTTTTTTT 14 V_DMRT2_01_M01147 TRANSFAC + 38597420 38597435 4.0E-06 CAGTTTGCAACTTTTT 16 V_DMRT2_01_M01147 TRANSFAC - 38603729 38603744 8.0E-06 GAATTTGCTGCATTGA 16 V_SRF_06_M02916 TRANSFAC - 38600789 38600805 0.0E+00 ATGTAAAAAAAAAGTTC 17 V_SRF_06_M02916 TRANSFAC - 38600790 38600806 1.0E-06 CATGTAAAAAAAAAGTT 17 V_SRF_06_M02916 TRANSFAC - 38601276 38601292 4.0E-06 GAGAAACAAAAAAAGAA 17 V_EWSR1FLI1_01_M02252 TRANSFAC - 38599779 38599796 6.0E-06 GGAGGGGAGCAAGCCTGG 18 V_EWSR1FLI1_01_M02252 TRANSFAC + 38601776 38601793 4.0E-06 GGAAAACAGGAAGGAGGT 18 V_HNF1A_Q5_M02013 TRANSFAC + 38603716 38603726 1.0E-06 GGTTAATTTTT 11 V_SMAD3_Q6_M00701 TRANSFAC + 38601625 38601633 3.0E-06 TGTCTGTCT 9 V_EKLF_Q5_M01874 TRANSFAC - 38602317 38602326 5.0E-06 CCACACCCAG 10 V_PAX4_02_M00377 TRANSFAC - 38603717 38603727 4.0E-06 TAAAAATTAAC 11 V_ARP1_01_M00155 TRANSFAC - 38602367 38602382 7.0E-06 CGAACTCCTGGCCTCA 16 V_CMAF_01_M01070 TRANSFAC + 38598798 38598816 2.0E-06 AAAAGTGCTGACATTACAG 19 V_HNF1A_01_M02162 TRANSFAC + 38603716 38603729 0.0E+00 GGTTAATTTTTAGT 14 V_DMRT1_01_M01146 TRANSFAC + 38597424 38597438 1.0E-05 TTGCAACTTTTTGGT 15 V_BRCA_01_M01082 TRANSFAC + 38601489 38601496 1.0E-05 TTCTGTTG 8 V_STAT1_05_M01260 TRANSFAC - 38603787 38603808 2.0E-06 AATTTCTGGGAATGCCCTTGTT 22 V_SMAD1_01_M01590 TRANSFAC - 38601337 38601348 0.0E+00 AAGAACAAAAGA 12 V_DMRT5_01_M01150 TRANSFAC + 38601455 38601469 6.0E-06 TTCTGTTTCAGTTGC 15 V_SPIB_03_M02076 TRANSFAC - 38601727 38601736 5.0E-06 TGAGGAAGTG 10 V_NANOG_02_M01247 TRANSFAC - 38601276 38601295 1.0E-06 ACTGAGAAACAAAAAAAGAA 20 V_NANOG_02_M01247 TRANSFAC - 38601333 38601352 4.0E-06 CAGGAAGAACAAAAGAGCAA 20

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.