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ICA1 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 3382 islet cell autoantigen 1, 69kDa chr7 - 8301182 - 8307185 8301682 Transcription Factor Binding Sites   Download all TFBS in the ICA1 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints NFE2_bZIP_DBD_dimeric_11_1 SELEX + 8300605 8300615 1.0E-05 GATGAGTCATA 11 NFE2_bZIP_DBD_dimeric_11_1 SELEX - 8300605 8300615 2.0E-06 TATGACTCATC 11 FOXO4_forkhead_DBD_dimeric_14_1 SELEX + 8300591 8300604 0.0E+00 AAAAACATGTTTGC 14 FOXO4_forkhead_DBD_dimeric_14_1 SELEX - 8300591 8300604 1.0E-06 GCAAACATGTTTTT 14 CENPB_CENPB_full_monomeric_15_1 SELEX - 8301085 8301099 8.0E-06 CCCGGTTCCAGCAAA 15 PDX1_homeodomain_DBD_dimeric_18_1 SELEX - 8300628 8300645 9.0E-06 GCATTTATTGGCCATTAA 18 GRHL1_CP2_full_dimeric_12_1 SELEX + 8300592 8300603 8.0E-06 AAAACATGTTTG 12 CUX1_CUT_DBD_dimeric_17_1 SELEX - 8299539 8299555 4.0E-06 ATAGATCACTAATGAAT 17 Pax4_MA0068.1 JASPAR - 8299513 8299542 8.0E-06 GAATCTTATCCCCCAACCCCACCACCATTC 30 BARHL2_homeodomain_full_dimeric_16_1 SELEX + 8300629 8300644 1.0E-06 TAATGGCCAATAAATG 16 Barhl1_homeodomain_DBD_dimeric_16_1 SELEX + 8300629 8300644 1.0E-06 TAATGGCCAATAAATG 16 NR2E1_nuclearreceptor_full_dimeric_14_1 SELEX + 8301288 8301301 7.0E-06 TTGTCAACAAGTCA 14 SP1_MA0079.2 JASPAR - 8301518 8301527 9.0E-06 CCCCTCCTCC 10 SPDEF_ETS_full_putative-multimer_15_1 SELEX - 8301558 8301572 5.0E-06 CGGGTCCCGGATCCC 15 ESR1_nuclearreceptor_DBD_dimeric_17_1 SELEX + 8302233 8302249 4.0E-06 TGCGTCACAATGACCTG 17 HESX1_homeodomain_DBD_dimeric_15_1 SELEX - 8300628 8300642 1.0E-06 TTTATTGGCCATTAA 15 LHX9_homeodomain_DBD_dimeric_13_1 SELEX + 8300629 8300641 3.0E-06 TAATGGCCAATAA 13 JDP2_bZIP_full_dimeric_9_1 SELEX + 8300606 8300614 4.0E-06 ATGAGTCAT 9 JDP2_bZIP_full_dimeric_9_1 SELEX - 8300606 8300614 2.0E-06 ATGACTCAT 9 Myf_MA0055.1 JASPAR - 8301663 8301674 5.0E-06 AAGCAGCAGGAG 12 HOXC13_homeodomain_DBD_monomeric_10_1 SELEX - 8300615 8300624 6.0E-06 CCTATAAAAT 10 GBX2_homeodomain_DBD_dimeric_14_1 SELEX + 8300628 8300641 1.0E-06 TTAATGGCCAATAA 14 GBX2_homeodomain_DBD_dimeric_14_1 SELEX - 8300628 8300641 1.0E-06 TTATTGGCCATTAA 14 FOXO3_forkhead_full_dimeric_14_1 SELEX + 8300591 8300604 1.0E-06 AAAAACATGTTTGC 14 FOXO3_forkhead_full_dimeric_14_1 SELEX - 8300591 8300604 1.0E-06 GCAAACATGTTTTT 14 Sox2_MA0143.1 JASPAR - 8302231 8302245 4.0E-06 TCATTGTGACGCAAA 15 FOXO6_forkhead_DBD_dimeric_14_1 SELEX + 8300591 8300604 1.0E-06 AAAAACATGTTTGC 14 FOXO6_forkhead_DBD_dimeric_14_1 SELEX - 8300591 8300604 0.0E+00 GCAAACATGTTTTT 14 HOXB13_homeodomain_DBD_monomeric_10_1 SELEX - 8300615 8300624 7.0E-06 CCTATAAAAT 10 FOXO1_forkhead_DBD_dimeric_14_1 SELEX + 8300591 8300604 0.0E+00 AAAAACATGTTTGC 14 FOXO1_forkhead_DBD_dimeric_14_1 SELEX - 8300591 8300604 1.0E-06 GCAAACATGTTTTT 14 V_KLF15_Q2_M01714 TRANSFAC + 8301519 8301532 4.0E-06 GAGGAGGGGAGGGG 14 V_KLF15_Q2_M01714 TRANSFAC - 8302188 8302201 9.0E-06 GAGCAGGGGCGGGG 14 V_APOLYA_B_M00310 TRANSFAC + 8300637 8300651 2.0E-06 AATAAATGCCTTATG 15 V_BACH2_01_M00490 TRANSFAC + 8300605 8300615 4.0E-06 GATGAGTCATA 11 V_STAT3STAT3_Q3_M01220 TRANSFAC - 8299596 8299609 3.0E-06 TTTATGGGAACCAT 14 V_GATA3_03_M00351 TRANSFAC - 8302644 8302653 7.0E-06 ATAGATAATA 10 V_FOXJ1_04_M02854 TRANSFAC + 8300979 8300993 9.0E-06 ACATAACAACAGGAT 15 V_SP1_Q6_01_M00931 TRANSFAC - 8302187 8302196 7.0E-06 GGGGCGGGGT 10 V_ZTA_Q2_M00711 TRANSFAC - 8300607 8300619 9.0E-06 AAAATATGACTCA 13 V_HNF4ALPHA_Q6_M00638 TRANSFAC - 8299486 8299498 6.0E-06 CAGAACTTTAAAC 13 V_SP1_03_M02281 TRANSFAC - 8301518 8301527 9.0E-06 CCCCTCCTCC 10 V_GATA_C_M00203 TRANSFAC + 8299287 8299297 3.0E-06 AGATAAGGAAA 11 V_SP1_02_M01303 TRANSFAC - 8301694 8301704 8.0E-06 GGGGCGGGGGC 11 V_SP1_02_M01303 TRANSFAC + 8301819 8301829 3.0E-06 GGGGCGGGGGG 11 V_SP1_02_M01303 TRANSFAC - 8302186 8302196 8.0E-06 GGGGCGGGGTC 11 V_HOXD13_01_M01404 TRANSFAC - 8300612 8300627 8.0E-06 GGTCCTATAAAATATG 16 V_EVX1_01_M01475 TRANSFAC + 8299536 8299552 5.0E-06 AAGATTCATTAGTGATC 17 V_TCFAP2E_04_M02926 TRANSFAC + 8302607 8302620 8.0E-06 CACAGGAAGAAAAA 14 V_WT1_Q6_01_M02036 TRANSFAC + 8301693 8301702 4.0E-06 CGCCCCCGCC 10 V_ELF4_04_M02850 TRANSFAC - 8300611 8300627 4.0E-06 GGTCCTATAAAATATGA 17 V_BACH1_01_M00495 TRANSFAC + 8300603 8300617 0.0E+00 GCGATGAGTCATATT 15 V_ZNF219_01_M01122 TRANSFAC - 8301820 8301831 7.0E-06 CTCCCCCCGCCC 12 V_MYF_01_M01302 TRANSFAC - 8301663 8301674 5.0E-06 AAGCAGCAGGAG 12 V_HOXB13_01_M01467 TRANSFAC - 8300612 8300627 3.0E-06 GGTCCTATAAAATATG 16 V_CART1_01_M00416 TRANSFAC - 8299532 8299549 3.0E-06 CACTAATGAATCTTATCC 18 V_ARID5A_03_M02736 TRANSFAC - 8302636 8302649 9.0E-06 ATAATATTAGGAAG 14 V_KROX_Q6_M00982 TRANSFAC + 8301691 8301704 0.0E+00 CGCGCCCCCGCCCC 14 V_OLF1_01_M00261 TRANSFAC + 8302114 8302135 5.0E-06 CTCTACTCCCCGGGGTCTCTCC 22 V_AP1_Q6_01_M00925 TRANSFAC - 8300606 8300614 4.0E-06 ATGACTCAT 9 V_SP1_Q6_M00196 TRANSFAC + 8301817 8301829 9.0E-06 AAGGGGCGGGGGG 13 V_SP1_Q6_M00196 TRANSFAC - 8302186 8302198 7.0E-06 CAGGGGCGGGGTC 13 V_MAZ_Q6_01_M02023 TRANSFAC + 8301515 8301528 4.0E-06 GAGGGAGGAGGGGA 14 V_MAZ_Q6_01_M02023 TRANSFAC + 8301518 8301531 0.0E+00 GGAGGAGGGGAGGG 14 V_LHX2_01_M01325 TRANSFAC + 8299536 8299552 8.0E-06 AAGATTCATTAGTGATC 17 V_TATA_C_M00216 TRANSFAC - 8300615 8300624 4.0E-06 CCTATAAAAT 10 V_ELF5_01_M01197 TRANSFAC + 8299289 8299299 4.0E-06 ATAAGGAAATG 11 V_JUNDM2_04_M02876 TRANSFAC + 8300602 8300617 3.0E-06 TGCGATGAGTCATATT 16 V_JUNDM2_04_M02876 TRANSFAC - 8300603 8300618 5.0E-06 AAATATGACTCATCGC 16 V_ERBETA_Q5_M01875 TRANSFAC + 8302236 8302250 5.0E-06 GTCACAATGACCTGG 15 V_RREB1_01_M00257 TRANSFAC - 8299519 8299532 2.0E-06 CCCCAACCCCACCA 14 V_AP1_C_M00199 TRANSFAC + 8300606 8300614 8.0E-06 ATGAGTCAT 9 V_POU6F1_01_M00465 TRANSFAC - 8302645 8302655 1.0E-05 ACATAGATAAT 11 V_AP1_01_M00517 TRANSFAC + 8300604 8300616 7.0E-06 CGATGAGTCATAT 13 V_SP1_01_M00008 TRANSFAC - 8302187 8302196 3.0E-06 GGGGCGGGGT 10 V_EMX2_01_M01461 TRANSFAC + 8299536 8299552 5.0E-06 AAGATTCATTAGTGATC 17 V_BLIMP1_Q6_M01066 TRANSFAC + 8301807 8301822 1.0E-05 AGGCGAGGGAAAGGGG 16 V_PAX8_B_M00328 TRANSFAC + 8299537 8299554 8.0E-06 AGATTCATTAGTGATCTA 18 V_SP4_Q5_M01273 TRANSFAC + 8301695 8301705 7.0E-06 CCCCCGCCCCG 11 V_IRX3_02_M01485 TRANSFAC - 8300917 8300933 9.0E-06 TTTTTACTTGTAGTACC 17 V_AP1_Q4_01_M00926 TRANSFAC + 8300607 8300614 1.0E-05 TGAGTCAT 8 V_TAL1_01_M01591 TRANSFAC - 8299285 8299297 2.0E-06 TTTCCTTATCTAC 13 V_TAL1_01_M01591 TRANSFAC - 8301610 8301622 2.0E-06 CTGCCTTCTCTGC 13 V_IPF1_05_M01255 TRANSFAC - 8299590 8299601 4.0E-06 AACCATTAATAA 12 V_GATA3_02_M00350 TRANSFAC - 8302644 8302653 8.0E-06 ATAGATAATA 10 V_NKX61_02_M01469 TRANSFAC + 8299588 8299603 3.0E-06 CCTTATTAATGGTTCC 16 V_FRA1_Q5_M01267 TRANSFAC + 8300607 8300614 1.0E-05 TGAGTCAT 8 V_FPM315_01_M01587 TRANSFAC + 8301515 8301526 0.0E+00 GAGGGAGGAGGG 12 V_PLZF_02_M01075 TRANSFAC + 8299477 8299505 2.0E-06 GTTTTTTGAGTTTAAAGTTCTGCTGAGGC 29 V_SOX2_01_M02246 TRANSFAC - 8302231 8302245 4.0E-06 TCATTGTGACGCAAA 15 V_FOXO1_04_M01969 TRANSFAC + 8300585 8300604 8.0E-06 ATGGACAAAAACATGTTTGC 20 V_SMAD3_Q6_M00701 TRANSFAC - 8300973 8300981 1.0E-05 TGTCTGCCT 9 V_HOMEZ_01_M01429 TRANSFAC + 8300992 8301008 2.0E-06 ATATGTTCGTTTCTAGA 17 V_NFE2_01_M00037 TRANSFAC + 8300604 8300614 1.0E-05 CGATGAGTCAT 11 V_SP1_Q2_01_M00933 TRANSFAC - 8301818 8301827 7.0E-06 CCCCGCCCCT 10 V_SP1_Q2_01_M00933 TRANSFAC + 8302188 8302197 7.0E-06 CCCCGCCCCT 10 V_GATA5_03_M02756 TRANSFAC + 8299282 8299298 5.0E-06 TCTGTAGATAAGGAAAT 17 V_BRN3C_01_M01408 TRANSFAC - 8299586 8299601 8.0E-06 AACCATTAATAAGGAT 16 V_IPF1_04_M01236 TRANSFAC - 8299589 8299598 2.0E-06 CATTAATAAG 10 V_GATA6_04_M02757 TRANSFAC + 8299282 8299298 7.0E-06 TCTGTAGATAAGGAAAT 17 V_SP1_Q4_01_M00932 TRANSFAC + 8301817 8301829 9.0E-06 AAGGGGCGGGGGG 13 V_SP1_Q4_01_M00932 TRANSFAC - 8302186 8302198 9.0E-06 CAGGGGCGGGGTC 13 V_TCF11MAFG_01_M00284 TRANSFAC - 8300598 8300619 8.0E-06 AAAATATGACTCATCGCAAACA 22 V_ATATA_B_M00311 TRANSFAC - 8299303 8299312 9.0E-06 TTACTTAAGT 10 V_GATA1_06_M00347 TRANSFAC - 8302644 8302653 1.0E-05 ATAGATAATA 10 V_ER_Q6_M00191 TRANSFAC - 8302232 8302250 2.0E-06 CCAGGTCATTGTGACGCAA 19

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.