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HFE Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 3077 hemochromatosis chr6 + 26082508 - 26088008 26087508 Transcription Factor Binding Sites   Download all TFBS in the HFE promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints RARB_nuclearreceptor_full_dimeric_16_1 SELEX - 26088417 26088432 1.0E-06 TCAGTTCAAACGTTCA 16 SPIC_ETS_full_monomeric_14_1 SELEX + 26088140 26088153 7.0E-06 CCAAACAGGAAGTT 14 Arx_homeodomain_DBD_dimeric_13_1 SELEX - 26088560 26088572 9.0E-06 AAAATCAAATAAG 13 FOXL1_forkhead_full_dimeric_13_1 SELEX + 26088027 26088039 7.0E-06 TTTAAATAAATCT 13 TFAP2B_TFAP_DBD_dimeric_11_1 SELEX - 26088066 26088076 1.0E-05 AGCCCCAGGCT 11 SOX7_HMG_full_dimeric_17_2 SELEX + 26088537 26088553 4.0E-06 TCTAAGTTACATTCATA 17 EBF1_MA0154.1 JASPAR + 26089046 26089055 5.0E-06 CCCCAAGGGA 10 SOX15_HMG_full_dimeric_15_3 SELEX + 26088538 26088552 3.0E-06 CTAAGTTACATTCAT 15 TFAP2A_TFAP_DBD_dimeric_11_1 SELEX - 26088066 26088076 9.0E-06 AGCCCCAGGCT 11 IRF5_IRF_full_monomeric_11_1 SELEX + 26087793 26087803 1.0E-06 AATCGAAACTA 11 IRF7_IRF_DBD_trimeric_17_1 SELEX + 26087792 26087808 1.0E-06 AAATCGAAACTAGCTTT 17 SPIB_ETS_DBD_monomeric_14_1 SELEX + 26088140 26088153 7.0E-06 CCAAACAGGAAGTT 14 IRF1_MA0050.1 JASPAR + 26087791 26087802 3.0E-06 AAAATCGAAACT 12 Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1 SELEX + 26087994 26088009 2.0E-06 AACCGCCCACTCCCTT 16 Sox17_HMG_DBD_dimeric_15_2 SELEX + 26088538 26088552 1.0E-06 CTAAGTTACATTCAT 15 SP1_MA0079.2 JASPAR + 26087612 26087621 7.0E-06 CCCCGCCCCC 10 SP1_MA0079.2 JASPAR + 26087953 26087962 3.0E-06 CCCCTCCCCC 10 ONECUT2_CUT_DBD_monomeric_14_1 SELEX + 26087789 26087802 6.0E-06 GAAAAATCGAAACT 14 Gfi_MA0038.1 JASPAR - 26088730 26088739 3.0E-06 AAAATCACTG 10 Alx4_homeodomain_DBD_dimeric_13_1 SELEX - 26088560 26088572 1.0E-05 AAAATCAAATAAG 13 Foxd3_MA0041.1 JASPAR + 26088405 26088416 4.0E-06 ATATGTTAGTTT 12 TFAP2C_TFAP_full_dimeric_11_1 SELEX - 26088066 26088076 8.0E-06 AGCCCCAGGCT 11 ELF5_ETS_full_monomeric_11_1 SELEX + 26088143 26088153 4.0E-06 AACAGGAAGTT 11 SOX18_HMG_full_dimeric_15_3 SELEX + 26088538 26088552 4.0E-06 CTAAGTTACATTCAT 15 SPI1_ETS_full_monomeric_14_1 SELEX + 26088140 26088153 9.0E-06 CCAAACAGGAAGTT 14 RARA_nuclearreceptor_full_dimeric_15_1 SELEX - 26088417 26088431 4.0E-06 CAGTTCAAACGTTCA 15 Tcfap2a_TFAP_DBD_dimeric_11_1 SELEX - 26088066 26088076 6.0E-06 AGCCCCAGGCT 11 ONECUT3_CUT_DBD_monomeric_14_1 SELEX + 26087789 26087802 6.0E-06 GAAAAATCGAAACT 14 V_NFAT_Q4_01_M00935 TRANSFAC + 26087786 26087795 3.0E-06 GTGGAAAAAT 10 V_E2F4_Q6_M02090 TRANSFAC + 26088246 26088255 1.0E-05 GCGCGAAAGA 10 V_SOX30_03_M02804 TRANSFAC + 26088428 26088443 1.0E-05 ACTGAACAATTCTCTT 16 V_FOXD3_01_M00130 TRANSFAC + 26088405 26088416 4.0E-06 ATATGTTAGTTT 12 V_BCL6_01_M01183 TRANSFAC + 26088682 26088697 6.0E-06 TTTTCTGATGTTATTT 16 V_HOXA13_02_M01297 TRANSFAC - 26088095 26088103 3.0E-06 AAATAAACC 9 V_IRF2_Q6_M01882 TRANSFAC + 26087789 26087804 8.0E-06 GAAAAATCGAAACTAG 16 V_SOX11_04_M02899 TRANSFAC - 26088427 26088440 2.0E-06 AGAATTGTTCAGTT 14 V_P53_DECAMER_Q2_M00761 TRANSFAC + 26089066 26089075 9.0E-06 AAACAAGTCT 10 V_IRF3_05_M02767 TRANSFAC + 26087790 26087803 0.0E+00 AAAAATCGAAACTA 14 V_SP1_03_M02281 TRANSFAC + 26087612 26087621 7.0E-06 CCCCGCCCCC 10 V_SP1_03_M02281 TRANSFAC + 26087953 26087962 3.0E-06 CCCCTCCCCC 10 V_STAT6_01_M00494 TRANSFAC + 26088099 26088106 7.0E-06 TATTTCCA 8 V_AFP1_Q6_M00616 TRANSFAC - 26088116 26088126 5.0E-06 AAAAACTGCAC 11 V_PU1_Q4_M01172 TRANSFAC + 26088036 26088054 3.0E-06 ATCTCGTAGTTCCTCACTT 19 V_BRN2_01_M00145 TRANSFAC - 26088096 26088111 0.0E+00 GACATTGGAAATAAAC 16 V_AR_03_M00956 TRANSFAC + 26088744 26088770 0.0E+00 TGTAGTGTAGCACAGTGTTCTGTGGGT 27 V_CETS1P54_02_M00074 TRANSFAC + 26088142 26088154 2.0E-06 AAACAGGAAGTTC 13 V_BARBIE_01_M00238 TRANSFAC + 26089720 26089734 6.0E-06 AGTAAAAGCAGGGAG 15 V_ETS_Q4_M00771 TRANSFAC - 26088145 26088156 6.0E-06 AAGAACTTCCTG 12 V_ETS_Q4_M00771 TRANSFAC - 26089741 26089752 1.0E-05 AACAGCTTCCTG 12 V_ELF4_04_M02850 TRANSFAC - 26088405 26088421 8.0E-06 GTTCAAAACTAACATAT 17 V_FOXA2_02_M02853 TRANSFAC - 26088403 26088417 4.0E-06 AAAACTAACATATAC 15 V_LMX1_01_M01409 TRANSFAC - 26088023 26088039 6.0E-06 AGATTTATTTAAAAGCA 17 V_PR_01_M00954 TRANSFAC + 26088744 26088770 4.0E-06 TGTAGTGTAGCACAGTGTTCTGTGGGT 27 V_TBX18_01_M01262 TRANSFAC + 26087784 26087802 6.0E-06 GGGTGGAAAAATCGAAACT 19 V_GFI1_01_M00250 TRANSFAC - 26088722 26088745 6.0E-06 CAGGGCAAAATCACTGTCAACTAA 24 V_SOX8_04_M02912 TRANSFAC + 26088545 26088558 7.0E-06 ACATTCATATCTGA 14 V_KROX_Q6_M00982 TRANSFAC + 26087948 26087961 8.0E-06 CCTGCCCCCTCCCC 14 V_KROX_Q6_M00982 TRANSFAC - 26088237 26088250 5.0E-06 CGCGCCCCCACCGC 14 V_EVI1_01_M00078 TRANSFAC - 26088551 26088566 4.0E-06 AAATAAGATCAGATAT 16 V_IRF_Q6_M00772 TRANSFAC - 26087791 26087805 9.0E-06 GCTAGTTTCGATTTT 15 V_ISRE_01_M00258 TRANSFAC - 26087789 26087803 1.0E-06 TAGTTTCGATTTTTC 15 V_ELF5_01_M01197 TRANSFAC + 26088143 26088153 6.0E-06 AACAGGAAGTT 11 V_GR_01_M00955 TRANSFAC + 26088744 26088770 3.0E-06 TGTAGTGTAGCACAGTGTTCTGTGGGT 27 V_MEF2_04_M00233 TRANSFAC - 26088687 26088708 7.0E-06 TGTAGTACTTGAAATAACATCA 22 V_SPIB_01_M01204 TRANSFAC + 26088140 26088156 0.0E+00 CCAAACAGGAAGTTCTT 17 V_IRF4_03_M02768 TRANSFAC + 26087791 26087805 2.0E-06 AAAATCGAAACTAGC 15 V_EBF1_01_M02267 TRANSFAC + 26089046 26089055 5.0E-06 CCCCAAGGGA 10 V_NCX_02_M01420 TRANSFAC - 26088022 26088038 4.0E-06 GATTTATTTAAAAGCAT 17 V_ARID3A_04_M02735 TRANSFAC - 26088023 26088039 3.0E-06 AGATTTATTTAAAAGCA 17 V_ARID3A_04_M02735 TRANSFAC + 26088024 26088040 2.0E-06 GCTTTTAAATAAATCTC 17 V_ISGF3G_03_M02771 TRANSFAC + 26087790 26087804 0.0E+00 AAAAATCGAAACTAG 15 V_TBP_06_M02814 TRANSFAC + 26088023 26088038 7.0E-06 TGCTTTTAAATAAATC 16 V_TBP_06_M02814 TRANSFAC + 26088025 26088040 1.0E-05 CTTTTAAATAAATCTC 16 V_IRX5_01_M01472 TRANSFAC + 26088400 26088416 9.0E-06 TAAGTATATGTTAGTTT 17 V_SP4_Q5_M01273 TRANSFAC + 26087611 26087621 9.0E-06 TCCCCGCCCCC 11 V_ZFP105_04_M02931 TRANSFAC + 26088024 26088040 8.0E-06 GCTTTTAAATAAATCTC 17 V_GFI1_Q6_M01067 TRANSFAC - 26088728 26088740 2.0E-06 CAAAATCACTGTC 13 V_SOX15_03_M02799 TRANSFAC + 26088427 26088443 8.0E-06 AACTGAACAATTCTCTT 17 V_IRF5_03_M02769 TRANSFAC + 26087790 26087804 0.0E+00 AAAAATCGAAACTAG 15 V_HIF1_Q3_M00797 TRANSFAC + 26087643 26087656 4.0E-06 GGGGACGTGCGGCC 14 V_AP4_01_M00005 TRANSFAC - 26088700 26088717 9.0E-06 AGAAGCAGCTGTAGTACT 18 V_NANOG_01_M01123 TRANSFAC - 26087665 26087676 0.0E+00 GGGCCCATTTCC 12 V_HDX_01_M01333 TRANSFAC - 26088561 26088577 2.0E-06 TAGTGAAAATCAAATAA 17 V_MEIS1_01_M00419 TRANSFAC - 26089654 26089665 1.0E-06 CTGTGACAGATC 12 V_ZBTB4_04_M02929 TRANSFAC - 26088723 26088738 2.0E-06 AAATCACTGTCAACTA 16 V_LMX1B_01_M01363 TRANSFAC + 26088023 26088039 9.0E-06 TGCTTTTAAATAAATCT 17 V_NRSF_01_M00256 TRANSFAC - 26087710 26087730 1.0E-05 TGCAGGACCGCGGTCTGCAAA 21 V_TBX15_02_M01264 TRANSFAC + 26088412 26088429 7.0E-06 AGTTTTGAACGTTTGAAC 18 V_LMO2COM_02_M00278 TRANSFAC + 26087923 26087931 7.0E-06 CAGATAGGG 9 V_ETS1_B_M00339 TRANSFAC + 26088144 26088158 1.0E-06 ACAGGAAGTTCTTCC 15 V_ZFP281_01_M01597 TRANSFAC - 26087953 26087963 7.0E-06 CGGGGGAGGGG 11 V_ZFP281_01_M01597 TRANSFAC - 26088005 26088015 5.0E-06 TGGGGGAAGGG 11 V_IRF6_03_M02770 TRANSFAC + 26087791 26087807 1.0E-06 AAAATCGAAACTAGCTT 17 V_SOX21_04_M02907 TRANSFAC - 26088426 26088442 9.0E-06 AGAGAATTGTTCAGTTC 17 V_IRX2_01_M01405 TRANSFAC + 26088400 26088416 7.0E-06 TAAGTATATGTTAGTTT 17 V_PR_02_M00957 TRANSFAC + 26088744 26088770 4.0E-06 TGTAGTGTAGCACAGTGTTCTGTGGGT 27 V_DR3_Q4_M00966 TRANSFAC + 26087838 26087858 9.0E-06 GGAGGACCTGCTCAACCCTAT 21 V_SP1_Q2_01_M00933 TRANSFAC + 26087612 26087621 4.0E-06 CCCCGCCCCC 10 V_UF1H3BETA_Q6_M01068 TRANSFAC - 26088004 26088017 0.0E+00 GTTGGGGGAAGGGA 14 V_MAFK_04_M02880 TRANSFAC - 26088114 26088128 6.0E-06 GAAAAAACTGCACAG 15 V_SOX5_07_M02909 TRANSFAC - 26088427 26088443 1.0E-05 AAGAGAATTGTTCAGTT 17 V_IRXB3_01_M01377 TRANSFAC + 26088400 26088416 3.0E-06 TAAGTATATGTTAGTTT 17 V_RNF96_01_M01199 TRANSFAC - 26087756 26087765 7.0E-06 GCCCGCAGCC 10 V_SEF1_C_M00214 TRANSFAC - 26087918 26087936 5.0E-06 GGGACCCCTATCTGCAGTT 19 V_PAX2_02_M00486 TRANSFAC - 26088094 26088102 8.0E-06 AATAAACCC 9

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.