Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

EEF2K Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 29904 eukaryotic elongation factor-2 kinase chr16 + 22212591 - 22218091 22217591 Transcription Factor Binding Sites   Download all TFBS in the EEF2K promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints TBX21_TBX_full_dimeric_16_1 SELEX + 22218973 22218988 6.0E-06 GCTGTGAAGTCACAGC 16 CTCF_MA0139.1 JASPAR + 22217522 22217540 2.0E-06 TGGCCACCTGGGGGCGGCC 19 THRB_nuclearreceptor_DBD_dimeric_20_1 SELEX + 22216150 22216169 9.0E-06 CTGAACTGAAATAGGGTGAA 20 THRB_nuclearreceptor_DBD_dimeric_20_1 SELEX - 22216150 22216169 6.0E-06 TTCACCCTATTTCAGTTCAG 20 VSX1_homeodomain_full_monomeric_11_1 SELEX - 22216085 22216095 3.0E-06 GGCCAATTAGC 11 SPIC_ETS_full_monomeric_14_1 SELEX + 22218198 22218211 2.0E-06 GAAATGGGGAAGTT 14 EN2_homeodomain_full_monomeric_10_1 SELEX - 22216085 22216094 5.0E-06 GCCAATTAGC 10 NHLH1_MA0048.1 JASPAR - 22218608 22218619 8.0E-06 GCGCAGCTGGGC 12 LHX2_homeodomain_DBD_dimeric_15_1 SELEX + 22216078 22216092 6.0E-06 GAAATATGCTAATTG 15 Lhx8_homeodomain_DBD_dimeric_12_1 SELEX + 22217136 22217147 1.0E-06 TAATTGCAATCG 12 Lhx8_homeodomain_DBD_dimeric_12_1 SELEX - 22217136 22217147 1.0E-06 CGATTGCAATTA 12 EWSR1-FLI1_MA0149.1 JASPAR - 22217628 22217645 2.0E-06 GGAAGGAGGGGAGCTGAG 18 POU1F1_POU_DBD_monomeric_14_1 SELEX + 22216080 22216093 0.0E+00 AATATGCTAATTGG 14 RARA_nuclearreceptor_DBD_dimeric_18_2 SELEX + 22222549 22222566 1.0E-06 AGGTTCAGAAGGTTAAGT 18 POU2F2_POU_DBD_monomeric_11_1 SELEX + 22216081 22216091 0.0E+00 ATATGCTAATT 11 Pax4_MA0068.1 JASPAR - 22213360 22213389 2.0E-06 GAATTATATCAGCAATTATAACAGCAATAA 30 SPIB_ETS_DBD_monomeric_14_1 SELEX + 22218198 22218211 1.0E-06 GAAATGGGGAAGTT 14 Klf4_MA0039.2 JASPAR - 22213215 22213224 1.0E-05 AGGGTGGGGC 10 OTX1_homeodomain_DBD_monomeric_8_1 SELEX - 22218215 22218222 1.0E-05 TTAATCCG 8 POU3F3_POU_DBD_monomeric_13_1 SELEX + 22216080 22216092 0.0E+00 AATATGCTAATTG 13 RUNX2_RUNX_DBD_dimeric_18_1 SELEX - 22213184 22213201 8.0E-06 TGGCCGCAGGCACCACAG 18 FOXI1_MA0042.1 JASPAR - 22217235 22217246 4.0E-06 GCTTGTTTGTAT 12 NR3C2_nuclearreceptor_DBD_dimeric_17_1 SELEX + 22217408 22217424 9.0E-06 CCGGACACTGTGTACTC 17 NR3C2_nuclearreceptor_DBD_dimeric_17_1 SELEX - 22217408 22217424 4.0E-06 GAGTACACAGTGTCCGG 17 EN1_homeodomain_DBD_monomeric_10_1 SELEX - 22216085 22216094 8.0E-06 GCCAATTAGC 10 NR2F1_nuclearreceptor_DBD_dimeric_16_1 SELEX + 22222549 22222564 3.0E-06 AGGTTCAGAAGGTTAA 16 GBX1_homeodomain_DBD_monomeric_10_1 SELEX - 22216085 22216094 7.0E-06 GCCAATTAGC 10 POU3F1_POU_DBD_monomeric_12_1 SELEX + 22216081 22216092 1.0E-06 ATATGCTAATTG 12 ID4_bHLH_DBD_dimeric_10_1 SELEX + 22213241 22213250 1.0E-06 TACACCTGTC 10 TFAP2C_TFAP_full_dimeric_12_1 SELEX + 22221661 22221672 4.0E-06 TGCCCTAGGCCA 12 SOX21_HMG_DBD_dimeric_16_1 SELEX + 22218253 22218268 6.0E-06 AGCAATGGGCGGTGAT 16 POU2F1_POU_DBD_monomeric_12_1 SELEX + 22216080 22216091 0.0E+00 AATATGCTAATT 12 LHX6_homeodomain_full_dimeric_12_1 SELEX + 22217136 22217147 2.0E-06 TAATTGCAATCG 12 LHX6_homeodomain_full_dimeric_12_1 SELEX - 22217136 22217147 1.0E-06 CGATTGCAATTA 12 SPI1_ETS_full_monomeric_14_1 SELEX + 22218198 22218211 0.0E+00 GAAATGGGGAAGTT 14 POU3F2_POU_DBD_monomeric_12_1 SELEX + 22216081 22216092 1.0E-06 ATATGCTAATTG 12 Sox1_HMG_DBD_dimeric_15_1 SELEX + 22221721 22221735 6.0E-06 TACACTTTGATTGCT 15 FOXC1_forkhead_DBD_dimeric_13_1 SELEX - 22213336 22213348 6.0E-06 AACAAAACAAAAA 13 FOXL1_MA0033.1 JASPAR - 22218865 22218872 5.0E-06 TATACATA 8 NR3C1_nuclearreceptor_DBD_dimeric_17_1 SELEX - 22217408 22217424 6.0E-06 GAGTACACAGTGTCCGG 17 RARA_nuclearreceptor_full_dimeric_15_1 SELEX + 22222549 22222563 1.0E-06 AGGTTCAGAAGGTTA 15 V_FOXP1_01_M00987 TRANSFAC + 22213333 22213352 1.0E-06 TCTTTTTTGTTTTGTTTTGT 20 V_FOXP1_01_M00987 TRANSFAC + 22213335 22213354 2.0E-06 TTTTTTGTTTTGTTTTGTGA 20 V_FOXP1_01_M00987 TRANSFAC - 22217119 22217138 5.0E-06 TTATTTGTGTAGTTTTAAAA 20 V_SRF_Q6_M00186 TRANSFAC - 22216110 22216123 7.0E-06 CTCCAAAAATGGAC 14 V_MEIS1BHOXA9_02_M00421 TRANSFAC + 22213352 22213365 0.0E+00 TGACAGCTTTATTG 14 V_OBOX6_01_M01445 TRANSFAC + 22218210 22218224 8.0E-06 TTGTGCGGATTAAAG 15 V_SPI1_01_M01203 TRANSFAC + 22218198 22218214 0.0E+00 GAAATGGGGAAGTTGTG 17 V_TGIF_01_M00418 TRANSFAC - 22213349 22213359 1.0E-06 AGCTGTCACAA 11 V_XVENT1_01_M00445 TRANSFAC + 22216139 22216151 3.0E-06 GGGCTATTTTCCT 13 V_USF_Q6_M00187 TRANSFAC - 22213269 22213278 2.0E-06 GTCACGTGGC 10 V_TCF3_01_M01594 TRANSFAC + 22213336 22213348 1.0E-06 TTTTTGTTTTGTT 13 V_MYOD_Q6_M00184 TRANSFAC + 22213241 22213250 9.0E-06 TACACCTGTC 10 V_TBX15_01_M01263 TRANSFAC + 22213229 22213247 9.0E-06 AGATGGGAGGATTACACCT 19 V_MAFK_03_M02776 TRANSFAC + 22216078 22216092 7.0E-06 GAAATATGCTAATTG 15 V_MAX_Q6_M01830 TRANSFAC + 22217535 22217546 8.0E-06 GCGGCCACGTGA 12 V_STAT3STAT3_Q3_M01220 TRANSFAC + 22218595 22218608 4.0E-06 TTTCGGGGAACCAG 14 V_DLX3_01_M01400 TRANSFAC + 22217130 22217146 5.0E-06 CACAAATAATTGCAATC 17 V_HMGIY_Q3_M01010 TRANSFAC - 22217131 22217145 1.0E-06 ATTGCAATTATTTGT 15 V_FOXD3_01_M00130 TRANSFAC - 22217129 22217140 5.0E-06 AATTATTTGTGT 12 V_BCL6_01_M01183 TRANSFAC + 22213335 22213350 0.0E+00 TTTTTTGTTTTGTTTT 16 V_GM397_03_M02760 TRANSFAC - 22221684 22221700 1.0E-06 CTGATGTGCACTGAAGT 17 V_GM397_03_M02760 TRANSFAC + 22221685 22221701 5.0E-06 CTTCAGTGCACATCAGC 17 V_ETS_B_M00340 TRANSFAC + 22218729 22218742 7.0E-06 AGCAGGAAACACTA 14 V_IK_Q5_M01169 TRANSFAC - 22221369 22221378 3.0E-06 TTTGGGAGGC 10 V_EBOX_Q6_01_M01034 TRANSFAC + 22213270 22213279 4.0E-06 CCACGTGACT 10 V_SP1_Q6_01_M00931 TRANSFAC - 22217574 22217583 4.0E-06 GGGGCGGGGC 10 V_ISL2_01_M01328 TRANSFAC + 22218829 22218844 9.0E-06 ATCTACCACTTAGTAT 16 V_MEIS1AHOXA9_01_M00420 TRANSFAC + 22213352 22213365 1.0E-06 TGACAGCTTTATTG 14 V_SRY_02_M00160 TRANSFAC - 22213335 22213346 3.0E-06 CAAAACAAAAAA 12 V_SRY_02_M00160 TRANSFAC - 22213340 22213351 8.0E-06 CAAAACAAAACA 12 V_GBX2_01_M01382 TRANSFAC + 22216082 22216098 4.0E-06 TATGCTAATTGGCCAGG 17 V_OCT1_01_M00135 TRANSFAC + 22216077 22216095 0.0E+00 TGAAATATGCTAATTGGCC 19 V_NKX25_Q6_M02108 TRANSFAC - 22218273 22218283 4.0E-06 GTCACTTGCAG 11 V_POU2F3_01_M01476 TRANSFAC + 22216079 22216094 3.0E-06 AAATATGCTAATTGGC 16 V_PLAG1_02_M01973 TRANSFAC + 22218301 22218316 2.0E-06 CCCCCCTCGGGGCCCC 16 V_HNF3_Q6_01_M01012 TRANSFAC + 22213335 22213352 3.0E-06 TTTTTTGTTTTGTTTTGT 18 V_GABPA_04_M02858 TRANSFAC + 22218374 22218389 9.0E-06 CCACCTTTCCCCTGAA 16 V_STAT5B_01_M00459 TRANSFAC + 22218410 22218424 3.0E-06 GAATTCCCGGAACCT 15 V_STAT5B_01_M00459 TRANSFAC - 22218410 22218424 8.0E-06 AGGTTCCGGGAATTC 15 V_AP2_Q6_M00189 TRANSFAC - 22218584 22218595 4.0E-06 ATCCCCCAGGCG 12 V_HEN1_01_M00068 TRANSFAC + 22217824 22217845 7.0E-06 CGTGGCCCCAGCTGCTTGCCCG 22 V_AP4_Q6_02_M01860 TRANSFAC + 22218610 22218622 1.0E-05 CCAGCTGCGCCCT 13 V_PU1_Q4_M01172 TRANSFAC - 22217285 22217303 9.0E-06 CTCGCTTAGTTCCTGTATT 19 V_PU1_Q4_M01172 TRANSFAC - 22218641 22218659 9.0E-06 AGATCTCACTTCCCCATGC 19 V_LYF1_01_M00141 TRANSFAC - 22221370 22221378 9.0E-06 TTTGGGAGG 9 V_CEBPB_01_M00109 TRANSFAC + 22222558 22222571 7.0E-06 AGGTTAAGTAATTT 14 V_BCL6_02_M01185 TRANSFAC + 22218189 22218202 8.0E-06 TGCTTTGGAGAAAT 14 V_TGIF2_01_M01407 TRANSFAC - 22213348 22213363 4.0E-06 ATAAAGCTGTCACAAA 16 V_AP1_Q6_M00174 TRANSFAC - 22221441 22221451 7.0E-06 AGTGACTCACT 11 V_SRF_C_M00215 TRANSFAC - 22216108 22216122 6.0E-06 TCCAAAAATGGACAC 15 V_GC_01_M00255 TRANSFAC - 22217572 22217585 2.0E-06 CAGGGGCGGGGCTG 14 V_SOX7_03_M02807 TRANSFAC - 22213329 22213350 7.0E-06 AAAACAAAACAAAAAAGACTCA 22 V_DBX2_01_M01360 TRANSFAC + 22217257 22217272 8.0E-06 GATCACTAATGATTTT 16 V_ZFP105_03_M02827 TRANSFAC - 22213333 22213347 7.0E-06 ACAAAACAAAAAAGA 15 V_CART1_01_M00416 TRANSFAC + 22217133 22217150 7.0E-06 AAATAATTGCAATCGTCA 18 V_STAT1_01_M00224 TRANSFAC - 22218407 22218427 1.0E-06 TGGAGGTTCCGGGAATTCGGG 21 V_CEBPD_Q6_M00621 TRANSFAC - 22222559 22222570 8.0E-06 AATTACTTAACC 12 V_AP1_Q4_M00188 TRANSFAC - 22221441 22221451 2.0E-06 AGTGACTCACT 11 V_SP1_Q6_M00196 TRANSFAC - 22217573 22217585 4.0E-06 CAGGGGCGGGGCT 13 V_OCT1_05_M00161 TRANSFAC - 22216080 22216093 1.0E-05 CCAATTAGCATATT 14 V_JUNDM2_04_M02876 TRANSFAC + 22221438 22221453 5.0E-06 AGGAGTGAGTCACTAA 16 V_JUNDM2_04_M02876 TRANSFAC - 22221439 22221454 9.0E-06 GTTAGTGACTCACTCC 16 V_OCT1_04_M00138 TRANSFAC + 22218858 22218880 1.0E-05 AGATGAGTATGTATATGTCAGGT 23 V_SOX12_04_M02900 TRANSFAC + 22217125 22217140 2.0E-06 AACTACACAAATAATT 16 V_SOX12_04_M02900 TRANSFAC + 22221424 22221439 3.0E-06 CTTCAGACAAAGGAAG 16 V_SPIB_01_M01204 TRANSFAC + 22217284 22217300 5.0E-06 GAATACAGGAACTAAGC 17 V_SPIB_01_M01204 TRANSFAC + 22218198 22218214 4.0E-06 GAAATGGGGAAGTTGTG 17 V_TCF1_07_M02919 TRANSFAC + 22218210 22218223 2.0E-06 TTGTGCGGATTAAA 14 V_CTCF_02_M01259 TRANSFAC + 22217519 22217538 4.0E-06 TGATGGCCACCTGGGGGCGG 20 V_STAT3_03_M01595 TRANSFAC - 22218408 22218423 4.0E-06 GGTTCCGGGAATTCGG 16 V_SOX11_03_M02795 TRANSFAC - 22213332 22213348 5.0E-06 AACAAAACAAAAAAGAC 17 V_CTCF_01_M01200 TRANSFAC + 22217521 22217540 1.0E-06 ATGGCCACCTGGGGGCGGCC 20 V_SRF_03_M01304 TRANSFAC - 22216111 22216123 3.0E-06 CTCCAAAAATGGA 13 V_ISGF4G_04_M02875 TRANSFAC - 22219009 22219022 9.0E-06 TAAAAACATTAGGA 14 V_FOXO1_Q5_M01216 TRANSFAC - 22213338 22213346 8.0E-06 CAAAACAAA 9 V_FOXO1_Q5_M01216 TRANSFAC - 22213343 22213351 8.0E-06 CAAAACAAA 9 V_ELK1_01_M00007 TRANSFAC + 22219073 22219088 5.0E-06 CTAAGAGGAAGCCAGT 16 V_SP4_Q5_M01273 TRANSFAC + 22217574 22217584 8.0E-06 GCCCCGCCCCT 11 V_USF_Q6_01_M00796 TRANSFAC + 22213268 22213279 2.0E-06 AGCCACGTGACT 12 V_USF_Q6_01_M00796 TRANSFAC + 22217537 22217548 6.0E-06 GGCCACGTGAGC 12 V_HFH8_01_M00294 TRANSFAC - 22217234 22217246 7.0E-06 GCTTGTTTGTATG 13 V_MRG2_01_M01395 TRANSFAC - 22213348 22213363 9.0E-06 ATAAAGCTGTCACAAA 16 V_FAC1_01_M00456 TRANSFAC - 22213336 22213349 0.0E+00 AAACAAAACAAAAA 14 V_CEBPA_01_M00116 TRANSFAC - 22222558 22222571 2.0E-06 AAATTACTTAACCT 14 V_OCT2_01_M01368 TRANSFAC + 22216079 22216094 3.0E-06 AAATATGCTAATTGGC 16 V_AREB6_02_M00413 TRANSFAC + 22213240 22213251 1.0E-05 TTACACCTGTCT 12 V_AP1FJ_Q2_M00172 TRANSFAC - 22221441 22221451 7.0E-06 AGTGACTCACT 11 V_FOXL1_02_M02857 TRANSFAC - 22213335 22213350 0.0E+00 AAAACAAAACAAAAAA 16 V_FOXL1_02_M02857 TRANSFAC - 22213340 22213355 4.0E-06 GTCACAAAACAAAACA 16 V_OCT1_Q6_M00195 TRANSFAC + 22216079 22216093 9.0E-06 AAATATGCTAATTGG 15 V_HEN1_02_M00058 TRANSFAC + 22217824 22217845 2.0E-06 CGTGGCCCCAGCTGCTTGCCCG 22 V_FOXJ3_06_M02855 TRANSFAC - 22213335 22213351 0.0E+00 CAAAACAAAACAAAAAA 17 V_FOXJ3_06_M02855 TRANSFAC - 22213340 22213356 9.0E-06 TGTCACAAAACAAAACA 17 V_T3R_Q6_M00963 TRANSFAC - 22217276 22217284 7.0E-06 CCTGTCCTT 9 V_MYOGNF1_01_M00056 TRANSFAC + 22213331 22213359 8.0E-06 AGTCTTTTTTGTTTTGTTTTGTGACAGCT 29 V_DMRT7_01_M01151 TRANSFAC + 22218447 22218460 1.0E-06 TTGCTGCATTGTTG 14 V_FOXO3_01_M00477 TRANSFAC + 22213336 22213349 6.0E-06 TTTTTGTTTTGTTT 14 V_STAT_01_M00223 TRANSFAC + 22218413 22218421 7.0E-06 TTCCCGGAA 9 V_GZF1_01_M01069 TRANSFAC - 22218434 22218445 4.0E-06 GGCGCGTCTATA 12 V_ZABC1_01_M01306 TRANSFAC - 22218758 22218765 1.0E-05 ATTCCAAC 8 V_ETS1_B_M00339 TRANSFAC - 22213173 22213187 8.0E-06 ACAGGAAGGGTCTGG 15 V_LHX61_02_M01422 TRANSFAC + 22216082 22216098 1.0E-05 TATGCTAATTGGCCAGG 17 V_SRF_Q5_01_M00922 TRANSFAC - 22216107 22216121 2.0E-06 CCAAAAATGGACACA 15 V_SRF_Q4_M00810 TRANSFAC - 22216105 22216122 1.0E-06 TCCAAAAATGGACACATG 18 V_OCT1_07_M00248 TRANSFAC + 22216080 22216091 0.0E+00 AATATGCTAATT 12 V_SRF_02_M01257 TRANSFAC - 22216106 22216123 3.0E-06 CTCCAAAAATGGACACAT 18 V_TBX22_01_M01195 TRANSFAC - 22213229 22213247 8.0E-06 AGGTGTAATCCTCCCATCT 19 V_STAT5A_01_M00457 TRANSFAC + 22218410 22218424 2.0E-06 GAATTCCCGGAACCT 15 V_STAT5A_01_M00457 TRANSFAC - 22218410 22218424 8.0E-06 AGGTTCCGGGAATTC 15 V_STAT5A_01_M00457 TRANSFAC + 22218593 22218607 6.0E-06 GATTTCGGGGAACCA 15 V_HFH3_01_M00289 TRANSFAC - 22217234 22217246 7.0E-06 GCTTGTTTGTATG 13 V_EWSR1FLI1_01_M02252 TRANSFAC - 22217628 22217645 2.0E-06 GGAAGGAGGGGAGCTGAG 18 V_SATB1_01_M01232 TRANSFAC + 22218822 22218833 6.0E-06 TATTAGTATCTA 12 V_EKLF_Q5_M01874 TRANSFAC + 22213216 22213225 9.0E-06 CCCCACCCTG 10 V_YY1_01_M00059 TRANSFAC + 22216107 22216123 0.0E+00 TGTGTCCATTTTTGGAG 17 V_SOX2_Q6_M01272 TRANSFAC + 22213332 22213347 5.0E-06 GTCTTTTTTGTTTTGT 16 V_S8_02_M01376 TRANSFAC + 22216082 22216098 8.0E-06 TATGCTAATTGGCCAGG 17 V_SP1_Q2_01_M00933 TRANSFAC + 22217575 22217584 7.0E-06 CCCCGCCCCT 10 V_ARP1_01_M00155 TRANSFAC - 22218354 22218369 5.0E-06 TGCGGCTCTGAGCCCT 16 V_LHX4_01_M01421 TRANSFAC + 22216082 22216098 5.0E-06 TATGCTAATTGGCCAGG 17 V_LPOLYA_B_M00318 TRANSFAC - 22213358 22213365 7.0E-06 CAATAAAG 8 V_MAFK_04_M02880 TRANSFAC + 22217132 22217146 5.0E-06 CAAATAATTGCAATC 15 V_IPF1_04_M01236 TRANSFAC + 22218513 22218522 2.0E-06 CATTAATAAG 10 V_P300_01_M00033 TRANSFAC + 22221435 22221448 9.0E-06 GGAAGGAGTGAGTC 14 V_SP1_Q4_01_M00932 TRANSFAC - 22217573 22217585 5.0E-06 CAGGGGCGGGGCT 13 V_BARX1_01_M01340 TRANSFAC + 22218240 22218255 7.0E-06 AAAGCAATTGGCAAGC 16 V_OBOX6_02_M03068 TRANSFAC + 22218210 22218224 8.0E-06 TTGTGCGGATTAAAG 15 V_ZID_01_M00085 TRANSFAC + 22213296 22213308 0.0E+00 GGGCTCTATCACC 13 V_LTF_Q6_M01692 TRANSFAC - 22218275 22218283 1.0E-05 GTCACTTGC 9 V_DMRT1_01_M01146 TRANSFAC + 22218447 22218461 1.0E-05 TTGCTGCATTGTTGG 15 V_SMAD1_01_M01590 TRANSFAC - 22213335 22213346 1.0E-06 CAAAACAAAAAA 12 V_SMAD1_01_M01590 TRANSFAC - 22213340 22213351 6.0E-06 CAAAACAAAACA 12 V_PAX2_02_M00486 TRANSFAC - 22221749 22221757 3.0E-06 ATTAAACTC 9 V_NANOG_02_M01247 TRANSFAC - 22213331 22213350 0.0E+00 AAAACAAAACAAAAAAGACT 20 V_NANOG_02_M01247 TRANSFAC - 22213336 22213355 1.0E-06 GTCACAAAACAAAACAAAAA 20

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.