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ICOS Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 29851 inducible T-cell co-stimulator chr2 + 204796470 - 204801970 204801470 Transcription Factor Binding Sites   Download all TFBS in the ICOS promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints TBX20_TBX_full_monomeric_11_1 SELEX - 204800059 204800069 5.0E-06 TGGGTGTGAAG 11 MYBL2_MYB_DBD_dimeric_14_1 SELEX + 204801514 204801527 3.0E-06 GACTGTTAACTGTT 14 MYBL2_MYB_DBD_dimeric_14_1 SELEX - 204801514 204801527 5.0E-06 AACAGTTAACAGTC 14 Foxa2_MA0047.2 JASPAR + 204798359 204798370 3.0E-06 TATTTACATTTT 12 TBX1_TBX_DBD_dimeric_20_2 SELEX - 204800060 204800079 6.0E-06 GTCTCAGCAGTGGGTGTGAA 20 MYF6_bHLH_full_dimeric_10_1 SELEX - 204796847 204796856 6.0E-06 AACAAGTGTT 10 RARB_nuclearreceptor_full_dimeric_16_1 SELEX + 204796924 204796939 6.0E-06 GCAGATCACAAGGTCA 16 FOXC2_forkhead_DBD_monomeric_12_1 SELEX - 204798357 204798368 7.0E-06 AATGTAAATAGA 12 NR2F1_nuclearreceptor_DBD_monomeric_13_1 SELEX + 204796931 204796943 5.0E-06 ACAAGGTCAAGAG 13 FOXL1_forkhead_full_dimeric_13_1 SELEX + 204796858 204796870 9.0E-06 ATTCAATAAATAG 13 SOX9_HMG_full_dimeric_17_3 SELEX + 204798350 204798366 7.0E-06 GATGAATTCTATTTACA 17 SRY_HMG_DBD_dimeric_16_1 SELEX + 204796783 204796798 5.0E-06 AAAAATTGTCATTGGT 16 ZNF232_C2H2_full_monomeric_19_1 SELEX - 204798356 204798374 1.0E-06 TTGTAAAATGTAAATAGAA 19 Esrrb_MA0141.1 JASPAR + 204796804 204796815 4.0E-06 TTCCCAAGGTCA 12 Esrrb_MA0141.1 JASPAR + 204796928 204796939 9.0E-06 ATCACAAGGTCA 12 SOX7_HMG_full_dimeric_17_2 SELEX + 204798350 204798366 4.0E-06 GATGAATTCTATTTACA 17 Pax4_MA0068.1 JASPAR - 204796728 204796757 9.0E-06 GAAAATTATCAAAACATGTTTGTATTTCAC 30 Pax4_MA0068.1 JASPAR + 204798961 204798990 2.0E-06 AAAAAATTAAAAGCAAACTAAAAGCACTTC 30 Pax4_MA0068.1 JASPAR + 204798963 204798992 5.0E-06 AAAATTAAAAGCAAACTAAAAGCACTTCCT 30 BARHL2_homeodomain_full_dimeric_16_1 SELEX - 204798365 204798380 6.0E-06 TAATCTTTGTAAAATG 16 BARHL2_homeodomain_full_dimeric_16_1 SELEX + 204798512 204798527 2.0E-06 TAATTGGGGTTTATCG 16 Barhl1_homeodomain_DBD_dimeric_16_1 SELEX - 204798365 204798380 7.0E-06 TAATCTTTGTAAAATG 16 Barhl1_homeodomain_DBD_dimeric_16_1 SELEX + 204798512 204798527 2.0E-06 TAATTGGGGTTTATCG 16 FOXJ3_forkhead_DBD_dimeric_14_1 SELEX - 204798359 204798372 9.0E-06 GTAAAATGTAAATA 14 FOXJ3_forkhead_DBD_dimeric_14_1 SELEX + 204801455 204801468 4.0E-06 GCAAATAGAAAACA 14 FOXJ3_forkhead_DBD_dimeric_14_1 SELEX - 204801517 204801530 9.0E-06 AGAAACAGTTAACA 14 Lhx8_homeodomain_DBD_dimeric_18_1 SELEX - 204798511 204798528 9.0E-06 CCGATAAACCCCAATTAC 18 HOXD8_homeodomain_DBD_monomeric_10_1 SELEX + 204798962 204798971 9.0E-06 AAAAATTAAA 10 HOXD8_homeodomain_DBD_monomeric_10_1 SELEX - 204799019 204799028 9.0E-06 GAAAATTAAC 10 ESRRG_nuclearreceptor_full_monomeric_10_1 SELEX + 204796807 204796816 4.0E-06 CCAAGGTCAT 10 ESRRG_nuclearreceptor_full_monomeric_10_1 SELEX + 204796931 204796940 7.0E-06 ACAAGGTCAA 10 SOX7_HMG_full_dimeric_16_1 SELEX + 204796783 204796798 2.0E-06 AAAAATTGTCATTGGT 16 SOX7_HMG_full_dimeric_16_1 SELEX - 204796783 204796798 8.0E-06 ACCAATGACAATTTTT 16 NR2F1_nuclearreceptor_DBD_dimeric_16_1 SELEX + 204796925 204796940 2.0E-06 CAGATCACAAGGTCAA 16 NR2F1_nuclearreceptor_DBD_dimeric_16_1 SELEX + 204796933 204796948 3.0E-06 AAGGTCAAGAGATCGA 16 TEAD3_TEA_DBD_dimeric_17_1 SELEX + 204796878 204796894 1.0E-06 GCATTGCAAACATACTT 17 Esrra_nuclearreceptor_DBD_monomeric_11_1 SELEX + 204796806 204796816 5.0E-06 CCCAAGGTCAT 11 ERF_ETS_DBD_monomeric_10_1 SELEX - 204798985 204798994 9.0E-06 ACAGGAAGTG 10 PPARG_MA0066.1 JASPAR + 204801181 204801200 8.0E-06 TTAGGTCCTGTTAACCCCCA 20 SOX21_HMG_DBD_dimeric_16_1 SELEX + 204796783 204796798 4.0E-06 AAAAATTGTCATTGGT 16 POU2F1_POU_DBD_monomeric_12_1 SELEX - 204798359 204798370 1.0E-05 AAAATGTAAATA 12 ESRRB_nuclearreceptor_DBD_monomeric_11_1 SELEX + 204796807 204796817 1.0E-06 CCAAGGTCATA 11 TEAD1_TEA_full_dimeric_17_1 SELEX + 204796878 204796894 1.0E-06 GCATTGCAAACATACTT 17 Sox3_HMG_DBD_dimeric_17_3 SELEX + 204798350 204798366 1.0E-06 GATGAATTCTATTTACA 17 Nr2f6_nuclearreceptor_DBD_dimeric_15_1 SELEX + 204796925 204796939 2.0E-06 CAGATCACAAGGTCA 15 Nr2f6_nuclearreceptor_DBD_dimeric_15_1 SELEX + 204796933 204796947 3.0E-06 AAGGTCAAGAGATCG 15 FOXB1_forkhead_DBD_monomeric_11_1 SELEX - 204798358 204798368 3.0E-06 AATGTAAATAG 11 FOXJ2_forkhead_DBD_dimeric_14_1 SELEX + 204801455 204801468 1.0E-06 GCAAATAGAAAACA 14 FOXJ2_forkhead_DBD_dimeric_14_1 SELEX - 204801517 204801530 4.0E-06 AGAAACAGTTAACA 14 V_NFAT_Q4_01_M00935 TRANSFAC + 204799002 204799011 7.0E-06 ATGGAAATTT 10 V_NFAT_Q4_01_M00935 TRANSFAC - 204799022 204799031 2.0E-06 CTGGAAAATT 10 V_FOXP1_01_M00987 TRANSFAC - 204798956 204798975 6.0E-06 TGCTTTTAATTTTTTTTCAT 20 V_DBX1_01_M01483 TRANSFAC + 204796857 204796873 4.0E-06 CATTCAATAAATAGTTG 17 V_DBX1_01_M01483 TRANSFAC + 204798960 204798976 4.0E-06 AAAAAAATTAAAAGCAA 17 V_FREAC7_01_M00293 TRANSFAC - 204798355 204798370 8.0E-06 AAAATGTAAATAGAAT 16 V_FOXP3_Q4_M00992 TRANSFAC - 204799632 204799648 8.0E-06 GAGAGTCTGTTACTTAT 17 V_CDX2_Q5_01_M01659 TRANSFAC + 204796860 204796870 5.0E-06 TCAATAAATAG 11 V_FLI1_Q6_M01208 TRANSFAC - 204798983 204798993 7.0E-06 CAGGAAGTGCT 11 V_FOXA2_04_M02749 TRANSFAC - 204798354 204798370 1.0E-06 AAAATGTAAATAGAATT 17 V_HMGIY_Q3_M01010 TRANSFAC - 204798959 204798973 1.0E-06 CTTTTAATTTTTTTT 15 V_HMGIY_Q3_M01010 TRANSFAC + 204799001 204799015 4.0E-06 AATGGAAATTTTTGC 15 V_EVI1_04_M00081 TRANSFAC + 204796737 204796751 7.0E-06 AAACATGTTTTGATA 15 V_BCL6_01_M01183 TRANSFAC - 204798961 204798976 4.0E-06 TTGCTTTTAATTTTTT 16 V_BCL6_01_M01183 TRANSFAC - 204798962 204798977 3.0E-06 TTTGCTTTTAATTTTT 16 V_HP1SITEFACTOR_Q6_M00725 TRANSFAC + 204798962 204798973 7.0E-06 AAAAATTAAAAG 12 V_FOXO4_02_M00476 TRANSFAC - 204801459 204801472 5.0E-06 CGGTTGTTTTCTAT 14 V_TCF4_Q5_01_M02033 TRANSFAC - 204801783 204801792 9.0E-06 ATCAAAGGCA 10 V_MAFB_03_M02879 TRANSFAC - 204799362 204799376 7.0E-06 TGAATGCAAAAAAAG 15 V_PROP1_01_M01294 TRANSFAC - 204798959 204798969 5.0E-06 TAATTTTTTTT 11 V_GABP_B_M00341 TRANSFAC - 204798983 204798994 8.0E-06 ACAGGAAGTGCT 12 V_OCT1_Q5_01_M00930 TRANSFAC + 204799364 204799374 5.0E-06 TTTTTTGCATT 11 V_MEF2_02_M00231 TRANSFAC + 204796854 204796875 7.0E-06 GTTCATTCAATAAATAGTTGTG 22 V_ISL2_01_M01328 TRANSFAC - 204803854 204803869 5.0E-06 ACAAATCACTTAACCT 16 V_IRF_Q6_01_M00972 TRANSFAC - 204801561 204801571 1.0E-05 AGAAGAGAAAG 11 V_IRF2_Q6_M01882 TRANSFAC - 204801558 204801573 7.0E-06 GCAGAAGAGAAAGAAA 16 V_NFAT3_Q3_M01734 TRANSFAC + 204799021 204799030 7.0E-06 TAATTTTCCA 10 V_GCNF_Q3_M02009 TRANSFAC + 204796932 204796941 1.0E-06 CAAGGTCAAG 10 V_FOXO3A_Q1_M01137 TRANSFAC - 204798355 204798366 9.0E-06 TGTAAATAGAAT 12 V_SOX11_04_M02899 TRANSFAC + 204796784 204796797 6.0E-06 AAAATTGTCATTGG 14 V_HNF3_Q6_01_M01012 TRANSFAC + 204798354 204798371 5.0E-06 AATTCTATTTACATTTTA 18 V_HFH4_01_M00742 TRANSFAC - 204798970 204798982 6.0E-06 TTTAGTTTGCTTT 13 V_NERF_Q2_M00531 TRANSFAC - 204801436 204801453 9.0E-06 GGAAAGGAAGTGGGTTTT 18 V_CMYB_Q5_M01821 TRANSFAC - 204798493 204798503 8.0E-06 CCTAACTGTCT 11 V_ATF4_Q2_M00514 TRANSFAC - 204801537 204801548 3.0E-06 CCTGACTTCATG 12 V_NFAT2_01_M01748 TRANSFAC + 204799002 204799010 5.0E-06 ATGGAAATT 9 V_PAX3_B_M00327 TRANSFAC - 204801405 204801425 5.0E-06 ATGTAGTGTCACGCTTACCAT 21 V_TCFAP2E_04_M02926 TRANSFAC + 204798953 204798966 5.0E-06 GGAATGAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC + 204798954 204798967 5.0E-06 GAATGAAAAAAAAT 14 V_HBP1_Q2_M01661 TRANSFAC + 204796859 204796867 4.0E-06 TTCAATAAA 9 V_HBP1_Q2_M01661 TRANSFAC - 204802962 204802970 3.0E-06 TTCAATGAA 9 V_MEF2A_Q6_M02024 TRANSFAC + 204801176 204801185 8.0E-06 TATTTTTAGG 10 V_RPC155_01_M01798 TRANSFAC + 204796937 204796952 3.0E-06 TCAAGAGATCGAGACT 16 V_ETS_Q4_M00771 TRANSFAC + 204798982 204798993 1.0E-06 AAGCACTTCCTG 12 V_TCF3_04_M02816 TRANSFAC + 204801372 204801388 6.0E-06 TTGGCATCAAAGAAGAA 17 V_ZFP105_03_M02827 TRANSFAC + 204798955 204798969 6.0E-06 AATGAAAAAAAATTA 15 V_CART1_01_M00416 TRANSFAC - 204798598 204798615 7.0E-06 TCCTAATCACAATTGCTT 18 V_NKX61_01_M00424 TRANSFAC - 204798961 204798973 1.0E-06 CTTTTAATTTTTT 13 V_HES1_Q2_M01009 TRANSFAC + 204798839 204798853 6.0E-06 AACTCTGGTGCCCAG 15 V_PXRRXR_02_M01153 TRANSFAC - 204798837 204798844 1.0E-05 AGAGTTCA 8 V_AP1_Q6_01_M00925 TRANSFAC - 204798944 204798952 9.0E-06 ATGACTTAA 9 V_IK1_01_M00086 TRANSFAC - 204796800 204796812 4.0E-06 CCTTGGGAATGCT 13 V_TTF1_Q6_M00794 TRANSFAC - 204798483 204798494 7.0E-06 CTCTCAAGTATT 12 V_HOX13_01_M00023 TRANSFAC - 204798499 204798528 5.0E-06 CCGATAAACCCCAATTACTCTACTTCCTAA 30 V_OCT1_04_M00138 TRANSFAC + 204798958 204798980 9.0E-06 GAAAAAAAATTAAAAGCAAACTA 23 V_OCT1_04_M00138 TRANSFAC - 204799359 204799381 3.0E-06 TAATTTGAATGCAAAAAAAGATG 23 V_HBP1_03_M02762 TRANSFAC - 204796851 204796866 2.0E-06 TTATTGAATGAACAAG 16 V_SOX12_04_M02900 TRANSFAC - 204801557 204801572 4.0E-06 CAGAAGAGAAAGAAAT 16 V_TCF7_03_M02817 TRANSFAC + 204801372 204801388 6.0E-06 TTGGCATCAAAGAAGAA 17 V_XFD2_01_M00268 TRANSFAC + 204796860 204796873 1.0E-05 TCAATAAATAGTTG 14 V_NCX_02_M01420 TRANSFAC + 204798960 204798976 1.0E-06 AAAAAAATTAAAAGCAA 17 V_CETS1P54_01_M00032 TRANSFAC - 204798985 204798994 9.0E-06 ACAGGAAGTG 10 V_OCT_Q6_M00795 TRANSFAC + 204799364 204799374 5.0E-06 TTTTTTGCATT 11 V_IRX5_01_M01472 TRANSFAC + 204796734 204796750 3.0E-06 TACAAACATGTTTTGAT 17 V_SF1_Q6_01_M01132 TRANSFAC - 204796807 204796815 7.0E-06 TGACCTTGG 9 V_MTF1_06_M02882 TRANSFAC + 204801457 204801470 5.0E-06 AAATAGAAAACAAC 14 V_TTF1_Q5_M02034 TRANSFAC + 204798482 204798495 1.0E-06 AAATACTTGAGAGA 14 V_POU5F1_01_M01307 TRANSFAC - 204799365 204799374 0.0E+00 AATGCAAAAA 10 V_GABPBETA_Q3_M01876 TRANSFAC - 204798984 204798994 1.0E-06 ACAGGAAGTGC 11 V_IPF1_05_M01255 TRANSFAC + 204798962 204798973 3.0E-06 AAAAATTAAAAG 12 V_OCT2_01_M01368 TRANSFAC - 204798356 204798371 7.0E-06 TAAAATGTAAATAGAA 16 V_OCT2_01_M01368 TRANSFAC - 204799362 204799377 9.0E-06 TTGAATGCAAAAAAAG 16 V_FOXL1_04_M02753 TRANSFAC - 204798354 204798370 2.0E-06 AAAATGTAAATAGAATT 17 V_FOXJ3_06_M02855 TRANSFAC - 204796737 204796753 8.0E-06 ATTATCAAAACATGTTT 17 V_NKX3A_02_M01383 TRANSFAC - 204803729 204803745 3.0E-06 AAGCAAGTACTTAGTTT 17 V_GFI1B_01_M01058 TRANSFAC - 204803857 204803868 7.0E-06 CAAATCACTTAA 12 V_ERR1_Q2_M00511 TRANSFAC + 204796804 204796817 5.0E-06 TTCCCAAGGTCATA 14 V_ERR2_01_M01589 TRANSFAC + 204796807 204796818 9.0E-06 CCAAGGTCATAT 12 V_ZBTB4_04_M02929 TRANSFAC + 204801481 204801496 6.0E-06 AATTCACTGTCAGCTT 16 V_NRF2_Q4_M00821 TRANSFAC - 204798527 204798539 5.0E-06 CTGCTGATTCACC 13 V_FOXO3_01_M00477 TRANSFAC - 204801459 204801472 6.0E-06 CGGTTGTTTTCTAT 14 V_MYB_Q3_M00773 TRANSFAC + 204798491 204798501 2.0E-06 AGAGACAGTTA 11 V_FOXA2_03_M02260 TRANSFAC + 204798359 204798370 3.0E-06 TATTTACATTTT 12 V_PLZF_02_M01075 TRANSFAC - 204798953 204798981 4.0E-06 TTAGTTTGCTTTTAATTTTTTTTCATTCC 29 V_PLZF_02_M01075 TRANSFAC + 204801570 204801598 7.0E-06 CTGCTTGCGCATTAAAGTTTTAACAGGTA 29 V_ESRRA_03_M02748 TRANSFAC + 204796804 204796820 2.0E-06 TTCCCAAGGTCATATGG 17 V_ESRRA_03_M02748 TRANSFAC + 204796928 204796944 9.0E-06 ATCACAAGGTCAAGAGA 17 V_ETS1_B_M00339 TRANSFAC - 204798980 204798994 5.0E-06 ACAGGAAGTGCTTTT 15 V_BBX_03_M02739 TRANSFAC + 204796852 204796866 9.0E-06 TTGTTCATTCAATAA 15 V_BBX_03_M02739 TRANSFAC - 204796852 204796866 2.0E-06 TTATTGAATGAACAA 15 V_BBX_03_M02739 TRANSFAC + 204796856 204796870 4.0E-06 TCATTCAATAAATAG 15 V_IRX2_01_M01405 TRANSFAC + 204796734 204796750 7.0E-06 TACAAACATGTTTTGAT 17 V_OCT1_07_M00248 TRANSFAC + 204798999 204799010 3.0E-06 TGAATGGAAATT 12 V_MYF6_03_M02781 TRANSFAC - 204796845 204796860 3.0E-06 AATGAACAAGTGTTTG 16 V_NUR77_Q5_M01217 TRANSFAC - 204796931 204796940 9.0E-06 TTGACCTTGT 10 V_SRF_06_M02916 TRANSFAC + 204798953 204798969 2.0E-06 GGAATGAAAAAAAATTA 17 V_SRF_06_M02916 TRANSFAC + 204798954 204798970 1.0E-06 GAATGAAAAAAAATTAA 17 V_SRF_06_M02916 TRANSFAC + 204798956 204798972 8.0E-06 ATGAAAAAAAATTAAAA 17 V_FOXJ2_01_M00422 TRANSFAC + 204796857 204796874 2.0E-06 CATTCAATAAATAGTTGT 18 V_FOXJ2_01_M00422 TRANSFAC - 204798354 204798371 7.0E-06 TAAAATGTAAATAGAATT 18 V_ERR1_Q2_01_M02093 TRANSFAC + 204796932 204796942 4.0E-06 CAAGGTCAAGA 11 V_HNF1A_Q5_M02013 TRANSFAC + 204799018 204799028 6.0E-06 AGTTAATTTTC 11 V_SATB1_01_M01232 TRANSFAC + 204801343 204801354 8.0E-06 CATAAGCAATAA 12 V_HOXD8_01_M01432 TRANSFAC + 204798960 204798976 3.0E-06 AAAAAAATTAAAAGCAA 17 V_SOX1_03_M02802 TRANSFAC + 204796853 204796868 1.0E-06 TGTTCATTCAATAAAT 16 V_SOX1_03_M02802 TRANSFAC - 204796854 204796869 9.0E-06 TATTTATTGAATGAAC 16 V_PPARG_02_M00515 TRANSFAC + 204801179 204801201 5.0E-06 TTTTAGGTCCTGTTAACCCCCAT 23 V_PAX4_02_M00377 TRANSFAC + 204798961 204798971 5.0E-06 AAAAAATTAAA 11 V_BARHL2_01_M01446 TRANSFAC - 204803854 204803869 1.0E-05 ACAAATCACTTAACCT 16 V_SOX15_04_M02903 TRANSFAC - 204798357 204798371 6.0E-06 TAAAATGTAAATAGA 15 V_LHX4_01_M01421 TRANSFAC + 204798507 204798523 5.0E-06 TAGAGTAATTGGGGTTT 17 V_HOXA10_01_M01464 TRANSFAC + 204798955 204798970 9.0E-06 AATGAAAAAAAATTAA 16 V_SOX5_07_M02909 TRANSFAC + 204796781 204796797 5.0E-06 TGAAAAATTGTCATTGG 17 V_IRXB3_01_M01377 TRANSFAC + 204796734 204796750 4.0E-06 TACAAACATGTTTTGAT 17 V_FOXK1_03_M02752 TRANSFAC - 204798354 204798370 2.0E-06 AAAATGTAAATAGAATT 17 V_PAX4_04_M00380 TRANSFAC + 204798961 204798990 1.0E-06 AAAAAATTAAAAGCAAACTAAAAGCACTTC 30 V_PAX2_02_M00486 TRANSFAC + 204801423 204801431 5.0E-06 CATAAACTC 9 V_DMRT5_01_M01150 TRANSFAC - 204799630 204799644 5.0E-06 GTCTGTTACTTATTC 15 V_DMRT5_01_M01150 TRANSFAC + 204801786 204801800 2.0E-06 CTTTGATACTGTGTC 15 V_OCT4_01_M01125 TRANSFAC - 204798360 204798374 5.0E-06 TTGTAAAATGTAAAT 15 V_OCT4_01_M01125 TRANSFAC - 204799366 204799380 1.0E-05 AATTTGAATGCAAAA 15 V_TCF4_01_M01705 TRANSFAC - 204801376 204801384 5.0E-06 TCTTTGATG 9

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.