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PLEK2 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 26499 pleckstrin 2 chr14 - 67878328 - 67883828 67878828 Transcription Factor Binding Sites   Download all TFBS in the PLEK2 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints NFE2_bZIP_DBD_dimeric_11_1 SELEX + 67881048 67881058 8.0E-06 CATGAGTCATA 11 NFE2_bZIP_DBD_dimeric_11_1 SELEX - 67881048 67881058 4.0E-06 TATGACTCATG 11 SP8_C2H2_DBD_monomeric_12_1 SELEX - 67877228 67877239 0.0E+00 GCCACGCCCACT 12 SP3_C2H2_DBD_monomeric_11_1 SELEX - 67877229 67877239 1.0E-06 GCCACGCCCAC 11 TBX1_TBX_DBD_dimeric_20_2 SELEX - 67881378 67881397 0.0E+00 TTCTCACATCAGGCTGTGAG 20 SOX10_HMG_full_dimeric_16_1 SELEX + 67878310 67878325 8.0E-06 GACAATATCCAGGGCT 16 Foxk1_forkhead_DBD_putatively-multimeric_11_1 SELEX + 67880836 67880846 2.0E-06 CAGACACAATC 11 KLF16_C2H2_DBD_monomeric_11_1 SELEX - 67877229 67877239 3.0E-06 GCCACGCCCAC 11 FOXG1_forkhead_DBD_dimeric_17_1 SELEX + 67881164 67881180 1.0E-06 GCAGACAGCAGTAAACA 17 En1_MA0027.1 JASPAR - 67881344 67881354 8.0E-06 TAATAGTTTTC 11 KLF14_C2H2_DBD_monomeric_14_1 SELEX - 67877227 67877240 1.0E-06 CGCCACGCCCACTT 14 GATA5_GATA_DBD_monomeric_8_1 SELEX + 67881429 67881436 7.0E-06 AGATAAGA 8 Creb5_bZIP_DBD_dimeric_12_1 SELEX - 67880599 67880610 9.0E-06 AATGACATAATA 12 GATA4_GATA_DBD_monomeric_8_1 SELEX + 67881429 67881436 7.0E-06 AGATAAGA 8 Klf4_MA0039.2 JASPAR + 67877230 67877239 1.0E-05 TGGGCGTGGC 10 Klf4_MA0039.2 JASPAR - 67880828 67880837 5.0E-06 TGGGTGGGGC 10 FOXK1_forkhead_DBD_putatively-multimeric_10_1 SELEX + 67880836 67880845 8.0E-06 CAGACACAAT 10 POU6F2_POU_DBD_dimeric_16_1 SELEX + 67880597 67880612 7.0E-06 TTTATTATGTCATTTT 16 SP1_MA0079.2 JASPAR - 67881184 67881193 3.0E-06 CCCCTCCCCC 10 SP1_C2H2_DBD_monomeric_11_1 SELEX - 67877229 67877239 4.0E-06 GCCACGCCCAC 11 Gata1_MA0035.2 JASPAR + 67881427 67881437 1.0E-06 TCAGATAAGAA 11 GATA3_GATA_full_monomeric_8_1 SELEX + 67881429 67881436 7.0E-06 AGATAAGA 8 NFIL3_bZIP_DBD_dimeric_12_1 SELEX - 67880599 67880610 2.0E-06 AATGACATAATA 12 Stat3_MA0144.1 JASPAR + 67880955 67880964 6.0E-06 TGCCAGGAAG 10 IRF9_IRF_full_trimeric_15_1 SELEX + 67880619 67880633 3.0E-06 AAGGAAACTGAATCC 15 Hltf_MA0109.1 JASPAR - 67883772 67883781 2.0E-06 AAACTTTTAT 10 JDP2_bZIP_full_dimeric_9_1 SELEX + 67881049 67881057 4.0E-06 ATGAGTCAT 9 JDP2_bZIP_full_dimeric_9_1 SELEX - 67881049 67881057 2.0E-06 ATGACTCAT 9 SPDEF_ETS_full_putative-multimer_16_1 SELEX + 67880957 67880972 9.0E-06 CCAGGAAGAAGTTAAG 16 IRF3_IRF_full_trimeric_21_1 SELEX + 67880614 67880634 5.0E-06 CAGTCAAGGAAACTGAATCCA 21 V_RUSH1A_02_M01107 TRANSFAC - 67883772 67883781 2.0E-06 AAACTTTTAT 10 V_STAT5A_Q6_M01890 TRANSFAC + 67882943 67882955 1.0E-06 GATTTTCTCAGAA 13 V_TST1_02_M01316 TRANSFAC + 67880634 67880650 1.0E-05 AAGTAGTTAAATAACTT 17 V_FLI1_Q6_M01208 TRANSFAC + 67878943 67878953 3.0E-06 CAGGAAGTCAG 11 V_GATA1_Q6_M02004 TRANSFAC + 67881424 67881438 0.0E+00 GCTTCAGATAAGAAT 15 V_BACH2_01_M00490 TRANSFAC + 67881048 67881058 2.0E-06 CATGAGTCATA 11 V_EVI1_04_M00081 TRANSFAC - 67880599 67880613 8.0E-06 GAAAATGACATAATA 15 V_NKX29_01_M01352 TRANSFAC - 67880629 67880645 8.0E-06 ATTTAACTACTTGGATT 17 V_NKX29_01_M01352 TRANSFAC + 67880630 67880646 9.0E-06 ATCCAAGTAGTTAAATA 17 V_ETS_B_M00340 TRANSFAC + 67878941 67878954 4.0E-06 GGCAGGAAGTCAGA 14 V_ETS_B_M00340 TRANSFAC - 67880984 67880997 3.0E-06 GACAGGAAGCAGGT 14 V_MAFB_03_M02879 TRANSFAC + 67881336 67881350 4.0E-06 GAGTTGCAGAAAACT 15 V_SP1_Q6_01_M00931 TRANSFAC - 67879037 67879046 7.0E-06 GGGGCGGGGT 10 V_IRF2_Q6_M01882 TRANSFAC + 67880620 67880635 1.0E-05 AGGAAACTGAATCCAA 16 V_NFAT3_Q3_M01734 TRANSFAC + 67880606 67880615 1.0E-05 TCATTTTCCA 10 V_HOXA4_01_M01370 TRANSFAC + 67880635 67880651 3.0E-06 AGTAGTTAAATAACTTG 17 V_HOXC4_01_M01369 TRANSFAC - 67880635 67880651 7.0E-06 CAAGTTATTTAACTACT 17 V_AP2_Q6_01_M00915 TRANSFAC + 67881065 67881077 1.0E-05 CCTTCCCCAGGCT 13 V_IRF3_05_M02767 TRANSFAC - 67883797 67883810 8.0E-06 AAGAATGGGAACTG 14 V_SP1_03_M02281 TRANSFAC - 67881184 67881193 3.0E-06 CCCCTCCCCC 10 V_GATA_C_M00203 TRANSFAC - 67880562 67880572 8.0E-06 AGATAAAACCT 11 V_HOXC6_01_M01406 TRANSFAC - 67880635 67880651 8.0E-06 CAAGTTATTTAACTACT 17 V_NERF_Q2_M00531 TRANSFAC - 67880981 67880998 7.0E-06 GGACAGGAAGCAGGTTCT 18 V_LHX3_01_M01471 TRANSFAC - 67880635 67880651 7.0E-06 CAAGTTATTTAACTACT 17 V_VSX1_01_M01335 TRANSFAC - 67880635 67880651 6.0E-06 CAAGTTATTTAACTACT 17 V_STAT4_Q4_M01666 TRANSFAC - 67882942 67882955 6.0E-06 TTCTGAGAAAATCA 14 V_TAL1_GATA1_01_M02243 TRANSFAC + 67881418 67881435 9.0E-06 CCTTTAGCTTCAGATAAG 18 V_BACH1_01_M00495 TRANSFAC + 67881046 67881060 1.0E-06 GGCATGAGTCATACC 15 V_GC_01_M00255 TRANSFAC - 67879035 67879048 3.0E-06 ATGGGGCGGGGTTG 14 V_DOBOX4_01_M01359 TRANSFAC - 67880588 67880604 9.0E-06 ATAATAAACACCTCATG 17 V_KROX_Q6_M00982 TRANSFAC - 67881185 67881198 8.0E-06 CCTGCCCCCTCCCC 14 V_ZBP89_Q4_M01816 TRANSFAC - 67881183 67881192 4.0E-06 CCCTCCCCCA 10 V_AP1_Q6_01_M00925 TRANSFAC - 67881049 67881057 4.0E-06 ATGACTCAT 9 V_HOXA3_07_M02869 TRANSFAC + 67881344 67881357 5.0E-06 GAAAACTATTAGGT 14 V_AP1_Q4_M00188 TRANSFAC + 67881373 67881383 1.0E-05 GGTGACTCACA 11 V_MAZ_Q6_01_M02023 TRANSFAC - 67881227 67881240 8.0E-06 GAGGGAGAGGAGGG 14 V_CDX2_Q5_M00729 TRANSFAC - 67883768 67883781 0.0E+00 AAACTTTTATAGCA 14 V_BCL6_Q3_M01171 TRANSFAC - 67880977 67880986 5.0E-06 GGTTCTAGGT 10 V_MEF2_03_M00232 TRANSFAC - 67880562 67880583 4.0E-06 TGTTGTACTTTAGATAAAACCT 22 V_MEF2_03_M00232 TRANSFAC - 67881394 67881415 5.0E-06 TGAATCTCTAATGATAGATTCT 22 V_TATA_C_M00216 TRANSFAC + 67883769 67883778 3.0E-06 GCTATAAAAG 10 V_JUNDM2_04_M02876 TRANSFAC + 67881370 67881385 5.0E-06 ATAGGTGACTCACAGC 16 Tal1_Gata1_MA0140.1 JASPAR + 67881418 67881435 9.0E-06 CCTTTAGCTTCAGATAAG 18 V_HBP1_03_M02762 TRANSFAC + 67880890 67880905 1.0E-06 TTCTTGAATGAATTCA 16 V_MEF2_04_M00233 TRANSFAC - 67880562 67880583 3.0E-06 TGTTGTACTTTAGATAAAACCT 22 V_GATA1_09_M02254 TRANSFAC + 67881427 67881437 1.0E-06 TCAGATAAGAA 11 V_AP1_C_M00199 TRANSFAC + 67881049 67881057 8.0E-06 ATGAGTCAT 9 V_TAXCREB_02_M00115 TRANSFAC - 67881043 67881057 7.0E-06 ATGACTCATGCCCCA 15 V_NKX3A_01_M00451 TRANSFAC + 67881362 67881373 4.0E-06 GTTTAAGTATAG 12 V_NCX_02_M01420 TRANSFAC - 67880634 67880650 6.0E-06 AAGTTATTTAACTACTT 17 V_STAT4_Q5_M02117 TRANSFAC - 67882946 67882955 5.0E-06 TTCTGAGAAA 10 V_PMX2B_01_M01356 TRANSFAC + 67880635 67880651 9.0E-06 AGTAGTTAAATAACTTG 17 V_AP1_01_M00517 TRANSFAC + 67881047 67881059 5.0E-06 GCATGAGTCATAC 13 V_SP1_01_M00008 TRANSFAC - 67879037 67879046 3.0E-06 GGGGCGGGGT 10 V_LMO2COM_01_M00277 TRANSFAC + 67879101 67879112 3.0E-06 CGCCAGGTGCTT 12 V_NKX23_01_M01457 TRANSFAC + 67878332 67878347 5.0E-06 CAGTAAGTGCTTAAGA 16 V_NKX23_01_M01457 TRANSFAC - 67878332 67878347 0.0E+00 TCTTAAGCACTTACTG 16 V_LIM1_01_M01418 TRANSFAC - 67880635 67880651 9.0E-06 CAAGTTATTTAACTACT 17 V_HOXB4_01_M01424 TRANSFAC - 67880635 67880651 7.0E-06 CAAGTTATTTAACTACT 17 V_BCL6B_04_M02844 TRANSFAC + 67879036 67879051 7.0E-06 AACCCCGCCCCATCCA 16 V_ZFP105_04_M02931 TRANSFAC + 67880636 67880652 4.0E-06 GTAGTTAAATAACTTGC 17 V_AP1_Q4_01_M00926 TRANSFAC + 67881050 67881057 1.0E-05 TGAGTCAT 8 V_GATA1_04_M00128 TRANSFAC + 67881426 67881438 0.0E+00 TTCAGATAAGAAT 13 V_SIRT6_01_M01797 TRANSFAC + 67881429 67881436 7.0E-06 AGATAAGA 8 V_NKX3A_02_M01383 TRANSFAC + 67878332 67878348 6.0E-06 CAGTAAGTGCTTAAGAC 17 V_NKX3A_02_M01383 TRANSFAC + 67880630 67880646 2.0E-06 ATCCAAGTAGTTAAATA 17 V_XBP1_01_M00251 TRANSFAC + 67878966 67878982 6.0E-06 TTTCTGACGTGACGTTT 17 V_FRA1_Q5_M01267 TRANSFAC + 67881050 67881057 1.0E-05 TGAGTCAT 8 V_ASCL2_04_M02841 TRANSFAC + 67879034 67879049 2.0E-06 CCAACCCCGCCCCATC 16 V_PLZF_02_M01075 TRANSFAC - 67881407 67881435 8.0E-06 CTTATCTGAAGCTAAAGGAATGAATCTCT 29 V_ZFP281_01_M01597 TRANSFAC + 67881183 67881193 1.0E-06 TGGGGGAGGGG 11 V_BBX_03_M02739 TRANSFAC - 67880890 67880904 4.0E-06 GAATTCATTCAAGAA 15 V_HOXC5_01_M01454 TRANSFAC - 67880635 67880651 4.0E-06 CAAGTTATTTAACTACT 17 V_GATA2_03_M00349 TRANSFAC + 67881427 67881436 7.0E-06 TCAGATAAGA 10 V_SOX18_04_M02905 TRANSFAC - 67880894 67880909 7.0E-06 TCTGTGAATTCATTCA 16 V_IPF1_Q4_01_M01013 TRANSFAC + 67881398 67881412 8.0E-06 TCTATCATTAGAGAT 15 V_LHX5_01_M01353 TRANSFAC - 67880635 67880651 7.0E-06 CAAGTTATTTAACTACT 17

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.