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GCH1 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 2643 GTP cyclohydrolase 1 chr14 - 55369042 - 55374542 55369542 Transcription Factor Binding Sites   Download all TFBS in the GCH1 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints LBX2_homeodomain_DBD_dimeric_13_1 SELEX - 55367401 55367413 0.0E+00 ATGGATCTAATTA 13 Hoxc10_homeodomain_DBD_monomeric_10_2 SELEX - 55369566 55369575 4.0E-06 GCCATAAAAA 10 EVX2_homeodomain_DBD_monomeric_10_1 SELEX + 55367399 55367408 1.0E-05 GGTAATTAGA 10 THRB_nuclearreceptor_DBD_dimeric_20_1 SELEX - 55367362 55367381 6.0E-06 CTGACCCTGAGACAGGTCAC 20 SP3_C2H2_DBD_monomeric_11_1 SELEX + 55368744 55368754 8.0E-06 TCCACGCCCAC 11 Hoxd9_homeodomain_DBD_monomeric_10_1 SELEX - 55369566 55369575 4.0E-06 GCCATAAAAA 10 Tp53_p53l_DBD_dimeric_18_1 SELEX + 55370086 55370103 9.0E-06 GCAAGTGTCACATCAAGT 18 IRF7_IRF_DBD_dimeric_14_1 SELEX + 55367645 55367658 9.0E-06 AGAAAACTGAAAGT 14 ALX3_homeodomain_full_monomeric_10_1 SELEX - 55367399 55367408 1.0E-05 TCTAATTACC 10 BARX1_homeodomain_DBD_dimeric_17_1 SELEX - 55367276 55367292 4.0E-06 TCATTTAAAGAGGATTA 17 FOXG1_forkhead_DBD_dimeric_17_1 SELEX + 55365131 55365147 5.0E-06 GTACACTACTGTAAACT 17 PDX1_homeodomain_DBD_dimeric_18_1 SELEX + 55367271 55367288 1.0E-05 GTTATTAATCCTCTTTAA 18 FOXL1_forkhead_full_dimeric_13_1 SELEX + 55366506 55366518 9.0E-06 ATTAAACAATCAC 13 CEBPA_MA0102.2 JASPAR + 55367706 55367714 4.0E-06 TTTTGCAAT 9 Alx1_homeodomain_DBD_monomeric_10_1 SELEX - 55367399 55367408 1.0E-05 TCTAATTACC 10 EWSR1-FLI1_MA0149.1 JASPAR + 55369720 55369737 2.0E-06 GCAGGGAGGGAAGGAAAA 18 OTX2_homeodomain_DBD_dimeric_15_1 SELEX + 55367274 55367288 1.0E-06 ATTAATCCTCTTTAA 15 BARHL2_homeodomain_full_dimeric_16_1 SELEX + 55367276 55367291 5.0E-06 TAATCCTCTTTAAATG 16 RORA_nuclearreceptor_DBD_dimeric_19_1 SELEX + 55370110 55370128 7.0E-06 TATGTGGGTCCCTATGTCT 19 IRF1_MA0050.1 JASPAR + 55367647 55367658 3.0E-06 AAAACTGAAAGT 12 Barhl1_homeodomain_DBD_dimeric_16_1 SELEX + 55367276 55367291 7.0E-06 TAATCCTCTTTAAATG 16 HOXD11_homeodomain_DBD_monomeric_10_2 SELEX - 55369567 55369576 7.0E-06 GGCCATAAAA 10 HOXC12_homeodomain_DBD_monomeric_9_1 SELEX + 55367721 55367729 8.0E-06 GTAAAAAAA 9 Foxq1_MA0040.1 JASPAR + 55367653 55367663 7.0E-06 GAAAGTTTATT 11 HOXD13_homeodomain_DBD_monomeric_10_1 SELEX - 55369566 55369575 8.0E-06 GCCATAAAAA 10 HOXC11_homeodomain_full_monomeric_11_2 SELEX - 55369566 55369576 1.0E-06 GGCCATAAAAA 11 OTX2_homeodomain_DBD_monomeric_8_1 SELEX + 55367275 55367282 7.0E-06 TTAATCCT 8 SRY_MA0084.1 JASPAR + 55366507 55366515 1.0E-06 TTAAACAAT 9 znf143_MA0088.1 JASPAR + 55367817 55367836 2.0E-06 GATTTCCCACCCTTCCTTTG 20 Otx1_homeodomain_DBD_dimeric_15_1 SELEX + 55367274 55367288 3.0E-06 ATTAATCCTCTTTAA 15 NFATC1_NFAT_full_dimeric_20_1 SELEX + 55367649 55367668 6.0E-06 AACTGAAAGTTTATTTTTCA 20 NFATC1_NFAT_full_dimeric_20_1 SELEX - 55367651 55367670 3.0E-06 ACTGAAAAATAAACTTTCAG 20 SOX9_HMG_full_dimeric_16_3 SELEX + 55367289 55367304 1.0E-06 ATGAATCTTCGCTCAT 16 MGA_TBX_DBD_dimeric_18_2 SELEX + 55367550 55367567 9.0E-06 ATTGTGAAATATCTCACA 18 MGA_TBX_DBD_dimeric_18_2 SELEX - 55367550 55367567 5.0E-06 TGTGAGATATTTCACAAT 18 NFATC1_NFAT_full_dimeric_15_1 SELEX + 55367241 55367255 3.0E-06 TTTCTAATGTGGAAT 15 NFATC1_NFAT_full_dimeric_15_1 SELEX - 55367241 55367255 6.0E-06 ATTCCACATTAGAAA 15 FOXC2_forkhead_DBD_dimeric_11_1 SELEX - 55367656 55367666 8.0E-06 AAAAATAAACT 11 GSX2_homeodomain_DBD_monomeric_10_1 SELEX + 55366502 55366511 4.0E-06 ACTCATTAAA 10 VENTX_homeodomain_DBD_monomeric_9_1 SELEX + 55369970 55369978 5.0E-06 ACCGATTAG 9 Foxd3_MA0041.1 JASPAR + 55367653 55367664 1.0E-05 GAAAGTTTATTT 12 TBX2_TBX_full_dimeric_18_1 SELEX + 55367550 55367567 1.0E-05 ATTGTGAAATATCTCACA 18 TBX2_TBX_full_dimeric_18_1 SELEX - 55367552 55367569 8.0E-06 TGTGTGAGATATTTCACA 18 PRDM1_C2H2_full_monomeric-or-dimeric_15_1 SELEX + 55367646 55367660 2.0E-06 GAAAACTGAAAGTTT 15 Hoxd9_homeodomain_DBD_monomeric_9_1 SELEX - 55369567 55369575 4.0E-06 GCCATAAAA 9 Pou5f1_MA0142.1 JASPAR + 55367805 55367819 5.0E-06 CTTTCACATTCTGAT 15 Sox3_HMG_DBD_dimeric_17_3 SELEX + 55367436 55367452 1.0E-05 TATGAATTCTCTTTAAG 17 DMBX1_homeodomain_DBD_monomeric_10_1 SELEX - 55367274 55367283 7.0E-06 GAGGATTAAT 10 SPI1_ETS_full_monomeric_14_1 SELEX + 55369798 55369811 1.0E-05 GAAAAGAGGCAGTC 14 Hoxa11_homeodomain_DBD_monomeric_11_1 SELEX - 55369566 55369576 2.0E-06 GGCCATAAAAA 11 CDX2_homeodomain_DBD_monomeric_9_1 SELEX - 55369567 55369575 8.0E-06 GCCATAAAA 9 CDX1_homeodomain_DBD_monomeric_9_1 SELEX - 55369567 55369575 8.0E-06 GCCATAAAA 9 HOXA10_homeodomain_DBD_monomeric_11_1 SELEX - 55369566 55369576 3.0E-06 GGCCATAAAAA 11 IRF2_MA0051.1 JASPAR + 55367646 55367663 3.0E-06 GAAAACTGAAAGTTTATT 18 V_FOXP1_01_M00987 TRANSFAC - 55367589 55367608 1.0E-06 TTGTGTGTGTGTGTGTGTGT 20 V_FOXP1_01_M00987 TRANSFAC - 55367593 55367612 1.0E-06 AAATTTGTGTGTGTGTGTGT 20 V_CEBPG_Q6_M00622 TRANSFAC + 55366503 55366515 3.0E-06 CTCATTAAACAAT 13 V_OBOX6_01_M01445 TRANSFAC - 55367273 55367287 2.0E-06 TAAAGAGGATTAATA 15 V_TCF3_01_M01594 TRANSFAC + 55367670 55367682 7.0E-06 TCTTTGTATTTTG 13 V_OBOX5_05_M03066 TRANSFAC - 55367270 55367286 1.0E-05 AAAGAGGATTAATAACT 17 V_BTEB3_Q5_M01865 TRANSFAC + 55367448 55367460 1.0E-06 TTAAGGGAGGATT 13 V_XFD1_01_M00267 TRANSFAC + 55365147 55365160 4.0E-06 TTTATAAACACTGT 14 V_DMRT3_01_M01148 TRANSFAC + 55367540 55367554 4.0E-06 ATTTCATTACATTGT 15 V_OBOX1_01_M01450 TRANSFAC - 55367271 55367287 1.0E-06 TAAAGAGGATTAATAAC 17 V_CEBP_Q3_M00770 TRANSFAC + 55367703 55367714 2.0E-06 AACTTTTGCAAT 12 V_ZFX_01_M01593 TRANSFAC + 55369288 55369303 1.0E-06 GCCCGGGCCGCGGCGG 16 V_BCL6_01_M01183 TRANSFAC - 55367728 55367743 9.0E-06 TTTCCAAATTCACTTT 16 V_DEAF1_02_M01002 TRANSFAC - 55369775 55369799 1.0E-05 TCGGGTTCGGCTCATTCCGCAATAA 25 V_HP1SITEFACTOR_Q6_M00725 TRANSFAC - 55367348 55367359 6.0E-06 AATTATCTAAAG 12 V_DEAF1_01_M01001 TRANSFAC - 55368948 55368972 3.0E-06 CGGCTCCAGGAAGTTTCCGGAGTTG 25 V_DEAF1_01_M01001 TRANSFAC - 55369687 55369711 4.0E-06 ACCCCTCCGGGCGTCTCCGGAGCCG 25 V_STAT_Q6_M00777 TRANSFAC + 55367685 55367697 1.0E-05 ATCTCTTCTGAGA 13 V_POU5F1_02_M02245 TRANSFAC + 55367805 55367819 5.0E-06 CTTTCACATTCTGAT 15 V_IK_Q5_M01169 TRANSFAC - 55367183 55367192 3.0E-06 TTTGGGAGGC 10 V_MAFB_03_M02879 TRANSFAC - 55367702 55367716 1.0E-06 CAATTGCAAAAGTTT 15 V_IRF_Q6_01_M00972 TRANSFAC + 55367647 55367657 1.0E-06 AAAACTGAAAG 11 V_IRF2_Q6_M01882 TRANSFAC + 55367645 55367660 3.0E-06 AGAAAACTGAAAGTTT 16 V_CEBP_C_M00201 TRANSFAC + 55367674 55367691 7.0E-06 TGTATTTTGAAATCTCTT 18 V_AP2_Q6_M00189 TRANSFAC + 55369020 55369031 6.0E-06 AGCCCGCGGGCG 12 V_HOXA2_01_M01402 TRANSFAC - 55367395 55367410 3.0E-06 GATCTAATTACCCAAA 16 V_HFH4_01_M00742 TRANSFAC - 55366508 55366520 1.0E-06 TAGTGATTGTTTA 13 V_PITX2_Q6_M02114 TRANSFAC - 55367197 55367206 1.0E-06 TGTAATCCCA 10 V_LYF1_01_M00141 TRANSFAC - 55367184 55367192 9.0E-06 TTTGGGAGG 9 V_CDX_Q5_M00991 TRANSFAC + 55365137 55365154 0.0E+00 TACTGTAAACTTTATAAA 18 V_CEBPB_01_M00109 TRANSFAC + 55367548 55367561 0.0E+00 ACATTGTGAAATAT 14 V_CEBPB_01_M00109 TRANSFAC + 55367675 55367688 0.0E+00 GTATTTTGAAATCT 14 V_AR_03_M00956 TRANSFAC + 55367245 55367271 1.0E-06 TAATGTGGAATGATGTGTTCTTTGCAG 27 V_WT1_Q6_01_M02036 TRANSFAC + 55368994 55369003 4.0E-06 CGCCCCCGCC 10 V_NFY_C_M00209 TRANSFAC - 55366506 55366519 9.0E-06 AGTGATTGTTTAAT 14 V_ELF4_04_M02850 TRANSFAC - 55367654 55367670 3.0E-06 ACTGAAAAATAAACTTT 17 V_CRX_Q4_M00623 TRANSFAC + 55367272 55367284 2.0E-06 TTATTAATCCTCT 13 V_OBOX5_02_M01480 TRANSFAC - 55367270 55367286 1.0E-05 AAAGAGGATTAATAACT 17 V_HOXA6_01_M01392 TRANSFAC - 55367395 55367410 7.0E-06 GATCTAATTACCCAAA 16 V_POU3F2_01_M00463 TRANSFAC + 55367266 55367279 4.0E-06 TTGCAGTTATTAAT 14 V_CEBPE_Q6_M01868 TRANSFAC - 55367677 55367690 1.0E-06 AGAGATTTCAAAAT 14 V_PR_01_M00954 TRANSFAC + 55367245 55367271 2.0E-06 TAATGTGGAATGATGTGTTCTTTGCAG 27 V_IRF2_01_M00063 TRANSFAC + 55367646 55367658 0.0E+00 GAAAACTGAAAGT 13 V_HOXB9_01_M01426 TRANSFAC - 55369563 55369578 8.0E-06 CGGGCCATAAAAAGGA 16 V_AP1_Q4_M00188 TRANSFAC - 55367339 55367349 5.0E-06 AGTGACTCACA 11 V_HOXB6_01_M01460 TRANSFAC + 55367395 55367410 3.0E-06 TTTGGGTAATTAGATC 16 V_MAZ_Q6_01_M02023 TRANSFAC + 55369721 55369734 4.0E-06 CAGGGAGGGAAGGA 14 V_AP2BETA_Q3_M01858 TRANSFAC + 55369251 55369266 2.0E-06 GCCTCGGGCCGCGGGG 16 V_EGR1_Q6_M01873 TRANSFAC - 55368993 55369002 4.0E-06 GCGGGGGCGG 10 V_IRF_Q6_M00772 TRANSFAC - 55367647 55367661 0.0E+00 TAAACTTTCAGTTTT 15 V_HNF1_Q6_01_M01011 TRANSFAC - 55367653 55367673 9.0E-06 AAGACTGAAAAATAAACTTTC 21 V_OBOX2_01_M01364 TRANSFAC - 55367271 55367287 4.0E-06 TAAAGAGGATTAATAAC 17 V_ELF5_01_M01197 TRANSFAC - 55367782 55367792 6.0E-06 AAAAGGAAATG 11 V_ELF5_01_M01197 TRANSFAC + 55368614 55368624 4.0E-06 ATAAGGAACTA 11 V_GR_01_M00955 TRANSFAC + 55367245 55367271 2.0E-06 TAATGTGGAATGATGTGTTCTTTGCAG 27 V_IK2_01_M00087 TRANSFAC - 55367456 55367467 3.0E-06 CTTTGGGAATCC 12 V_HBP1_03_M02762 TRANSFAC + 55367282 55367297 7.0E-06 TCTTTAAATGAATCTT 16 V_GR_Q6_M00192 TRANSFAC + 55367249 55367267 3.0E-06 GTGGAATGATGTGTTCTTT 19 V_HFH1_01_M00129 TRANSFAC + 55367653 55367664 2.0E-06 GAAAGTTTATTT 12 V_VMYB_01_M00003 TRANSFAC - 55367267 55367276 8.0E-06 AATAACTGCA 10 V_SRF_Q5_02_M01007 TRANSFAC - 55365040 55365058 8.0E-06 AAGCTCCTTTCATGGTAAG 19 V_CTCF_02_M01259 TRANSFAC - 55370051 55370070 1.0E-05 ACCTGGCCCCTAGGTGGCAG 20 V_OCT4_02_M01124 TRANSFAC + 55367806 55367820 3.0E-06 TTTCACATTCTGATT 15 V_SRF_03_M01304 TRANSFAC + 55365042 55365054 6.0E-06 TACCATGAAAGGA 13 V_BLIMP1_Q6_M01066 TRANSFAC + 55367725 55367740 1.0E-06 AAAAAAGTGAATTTGG 16 V_ISGF4G_04_M02875 TRANSFAC + 55367738 55367751 9.0E-06 TGGAAACAGAACTA 14 V_HOXD9_Q2_M01834 TRANSFAC + 55366502 55366511 3.0E-06 ACTCATTAAA 10 V_IRF7_01_M00453 TRANSFAC + 55367644 55367661 3.0E-06 CAGAAAACTGAAAGTTTA 18 V_HFH8_01_M00294 TRANSFAC - 55365147 55365159 3.0E-06 CAGTGTTTATAAA 13 V_HOXB7_01_M01396 TRANSFAC - 55367266 55367281 6.0E-06 GGATTAATAACTGCAA 16 V_FXR_IR1_Q6_M00767 TRANSFAC - 55367375 55367387 7.0E-06 GAATTTCTGACCC 13 V_OBOX2_02_M03064 TRANSFAC - 55367271 55367287 4.0E-06 TAAAGAGGATTAATAAC 17 V_CEBPA_01_M00116 TRANSFAC - 55367703 55367716 8.0E-06 CAATTGCAAAAGTT 14 V_IPF1_05_M01255 TRANSFAC + 55366502 55366513 2.0E-06 ACTCATTAAACA 12 V_FOXL1_02_M02857 TRANSFAC - 55367671 55367686 8.0E-06 ATTTCAAAATACAAAG 16 V_PITX1_01_M01484 TRANSFAC - 55367271 55367287 1.0E-06 TAAAGAGGATTAATAAC 17 V_TFIIA_Q6_M00707 TRANSFAC + 55365045 55365056 9.0E-06 CATGAAAGGAGC 12 V_NFY_01_M00287 TRANSFAC - 55369603 55369618 9.0E-06 GCCGGCCAATGGGAGC 16 V_DOBOX5_01_M01463 TRANSFAC - 55367270 55367286 1.0E-06 AAAGAGGATTAATAACT 17 V_OTX2_01_M01387 TRANSFAC - 55367270 55367286 2.0E-06 AAAGAGGATTAATAACT 17 V_PITX2_Q2_M00482 TRANSFAC - 55367196 55367206 1.0E-06 TGTAATCCCAG 11 V_T3RBETA_Q6_01_M02119 TRANSFAC - 55369034 55369050 7.0E-06 AGACCATCTCAGGTCAG 17 V_CEBPB_Q6_M01896 TRANSFAC + 55367551 55367560 4.0E-06 TTGTGAAATA 10 V_SRF_Q5_01_M00922 TRANSFAC + 55365044 55365058 6.0E-06 CCATGAAAGGAGCTT 15 V_IRF1_Q6_01_M01881 TRANSFAC - 55367646 55367659 0.0E+00 AACTTTCAGTTTTC 14 V_IRF1_Q6_01_M01881 TRANSFAC + 55367803 55367816 8.0E-06 CTCTTTCACATTCT 14 V_SRF_06_M02916 TRANSFAC - 55367654 55367670 4.0E-06 ACTGAAAAATAAACTTT 17 V_EWSR1FLI1_01_M02252 TRANSFAC + 55369720 55369737 2.0E-06 GCAGGGAGGGAAGGAAAA 18 V_IPF1_Q4_01_M01013 TRANSFAC + 55367397 55367411 2.0E-06 TGGGTAATTAGATCC 15 V_GSC_01_M01428 TRANSFAC + 55367270 55367286 2.0E-06 AGTTATTAATCCTCTTT 17 V_PR_02_M00957 TRANSFAC + 55367245 55367271 1.0E-06 TAATGTGGAATGATGTGTTCTTTGCAG 27 V_IRF1_01_M00062 TRANSFAC + 55367646 55367658 0.0E+00 GAAAACTGAAAGT 13 V_MOX1_01_M01443 TRANSFAC - 55367395 55367410 4.0E-06 GATCTAATTACCCAAA 16 V_PITX2_01_M01447 TRANSFAC - 55367270 55367286 0.0E+00 AAAGAGGATTAATAACT 17 V_HOXD3_01_M01338 TRANSFAC + 55367395 55367410 8.0E-06 TTTGGGTAATTAGATC 16 V_CEBP_Q2_01_M00912 TRANSFAC - 55367703 55367714 4.0E-06 ATTGCAAAAGTT 12 V_NFYA_Q5_M02106 TRANSFAC - 55369603 55369616 3.0E-06 CGGCCAATGGGAGC 14 V_OBOX5_01_M01381 TRANSFAC - 55367270 55367286 4.0E-06 AAAGAGGATTAATAACT 17 V_OBOX6_02_M03068 TRANSFAC - 55367273 55367287 2.0E-06 TAAAGAGGATTAATA 15 V_OBOX3_02_M03065 TRANSFAC - 55367271 55367287 5.0E-06 TAAAGAGGATTAATAAC 17 V_LTF_Q6_M01692 TRANSFAC - 55368645 55368653 6.0E-06 GGCACTTGC 9 V_TCF3_05_M02920 TRANSFAC + 55367717 55367731 2.0E-06 AGGGGTAAAAAAAAG 15 V_TCF3_05_M02920 TRANSFAC + 55367718 55367732 4.0E-06 GGGGTAAAAAAAAGT 15 V_OTX1_01_M01366 TRANSFAC - 55367270 55367286 0.0E+00 AAAGAGGATTAATAACT 17 V_OBOX6_06_M03067 TRANSFAC + 55367270 55367286 4.0E-06 AGTTATTAATCCTCTTT 17 V_OBOX3_01_M01466 TRANSFAC - 55367271 55367287 5.0E-06 TAAAGAGGATTAATAAC 17 V_PAX4_04_M00380 TRANSFAC - 55367251 55367280 1.0E-06 GATTAATAACTGCAAAGAACACATCATTCC 30 V_HOX13_02_M01452 TRANSFAC - 55367395 55367410 1.0E-05 GATCTAATTACCCAAA 16 V_CEBPA_Q6_M01866 TRANSFAC + 55367703 55367715 0.0E+00 AACTTTTGCAATT 13 V_OCT4_01_M01125 TRANSFAC + 55367323 55367337 5.0E-06 ATTTCTCAAGTAAAT 15 V_OTX3_01_M01403 TRANSFAC - 55367271 55367287 1.0E-06 TAAAGAGGATTAATAAC 17

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.