Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

GCG Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 2641 glucagon chr2 - 163008414 - 163013914 163008914 Transcription Factor Binding Sites   Download all TFBS in the GCG promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints FOXB1_forkhead_DBD_dimeric_18_1 SELEX - 163006005 163006022 7.0E-06 ATTTTAAATGTTGATTGT 18 POU4F2_POU_full_monomeric_16_1 SELEX - 163006207 163006222 6.0E-06 ATGAATAATACATCTG 16 POU3F3_POU_DBD_monomeric_12_1 SELEX - 163006211 163006222 9.0E-06 ATGAATAATACA 12 TFAP2B_TFAP_DBD_dimeric_11_1 SELEX + 163006170 163006180 1.0E-06 AGCCTCAGGCT 11 TFAP2B_TFAP_DBD_dimeric_11_1 SELEX - 163006170 163006180 3.0E-06 AGCCTGAGGCT 11 TFAP2A_TFAP_DBD_dimeric_11_1 SELEX + 163006170 163006180 1.0E-06 AGCCTCAGGCT 11 TFAP2A_TFAP_DBD_dimeric_11_1 SELEX - 163006170 163006180 6.0E-06 AGCCTGAGGCT 11 SCRT2_C2H2_DBD_monomeric_13_1 SELEX + 163012207 163012219 9.0E-06 AAGCAACAGCTGA 13 HOMEZ_HOMEZ_DBD_monomer-or-dimer_12_1 SELEX - 163010476 163010487 0.0E+00 AAAACGATTAAA 12 POU4F3_POU_DBD_monomeric_16_1 SELEX - 163006207 163006222 2.0E-06 ATGAATAATACATCTG 16 POU4F3_POU_DBD_monomeric_16_1 SELEX + 163006210 163006225 6.0E-06 ATGTATTATTCATTTA 16 CUX1_CUT_DBD_dimeric_18_1 SELEX - 163010407 163010424 4.0E-06 ATCATACATTAAATCAAT 18 FOXJ3_forkhead_DBD_dimeric_14_1 SELEX + 163006001 163006014 1.0E-06 GTCCACAATCAACA 14 HNF1A_homeodomain_full_dimeric_15_1 SELEX - 163006213 163006227 6.0E-06 TATAAATGAATAATA 15 HNF4A_nuclearreceptor_full_dimeric_16_1 SELEX - 163006248 163006263 7.0E-06 AATTACAAAGTCTAGA 16 Tcf21_bHLH_DBD_dimeric_14_1 SELEX + 163006191 163006204 8.0E-06 ATACCAGCTGTCGG 14 Tcf21_bHLH_DBD_dimeric_14_1 SELEX - 163006191 163006204 5.0E-06 CCGACAGCTGGTAT 14 znf143_MA0088.1 JASPAR + 163006067 163006086 2.0E-06 CCTTATCCATCATGCCACCC 20 NFATC1_NFAT_full_dimeric_20_1 SELEX + 163006320 163006339 4.0E-06 AAGGGAAAAAATCATTTTAA 20 NFATC1_NFAT_full_dimeric_20_1 SELEX + 163013892 163013911 2.0E-06 TCTGGAAAGACTTTTTTTCT 20 VENTX_homeodomain_DBD_monomeric_9_1 SELEX - 163010477 163010485 9.0E-06 AACGATTAA 9 POU1F1_POU_DBD_monomeric_17_1 SELEX - 163006209 163006225 2.0E-06 TAAATGAATAATACATC 17 HNF1B_homeodomain_full_dimeric_13_1 SELEX - 163006214 163006226 1.0E-05 ATAAATGAATAAT 13 TBX2_TBX_full_monomeric_11_1 SELEX + 163010339 163010349 6.0E-06 AAGGTGTCAAG 11 POU3F1_POU_DBD_monomeric_12_2 SELEX - 163006211 163006222 2.0E-06 ATGAATAATACA 12 Hltf_MA0109.1 JASPAR + 163010372 163010381 6.0E-06 ATACTTATAA 10 TFAP2C_TFAP_full_dimeric_11_1 SELEX + 163006170 163006180 1.0E-06 AGCCTCAGGCT 11 TFAP2C_TFAP_full_dimeric_11_1 SELEX - 163006170 163006180 2.0E-06 AGCCTGAGGCT 11 GCM1_GCM_full_monomeric_11_1 SELEX - 163005643 163005653 1.0E-05 AATGCTGGTAC 11 TFAP4_bHLH_full_dimeric_10_1 SELEX + 163012211 163012220 5.0E-06 AACAGCTGAC 10 Myf_MA0055.1 JASPAR + 163012207 163012218 0.0E+00 AAGCAACAGCTG 12 HMX2_homeodomain_DBD_monomeric_11_1 SELEX - 163010475 163010485 9.0E-06 AACGATTAAAA 11 HNF1B_homeodomain_full_dimeric_15_1 SELEX - 163006213 163006227 9.0E-06 TATAAATGAATAATA 15 BHLHA15_bHLH_DBD_dimeric_10_1 SELEX - 163006043 163006052 5.0E-06 ACCATATGTA 10 NFIA_NFI_full_monomeric_10_1 SELEX - 163010299 163010308 9.0E-06 AGTGCCAAGA 10 Tcfap2a_TFAP_DBD_dimeric_11_1 SELEX + 163006170 163006180 1.0E-06 AGCCTCAGGCT 11 Tcfap2a_TFAP_DBD_dimeric_11_1 SELEX - 163006170 163006180 2.0E-06 AGCCTGAGGCT 11 POU4F1_POU_DBD_monomeric_14_1 SELEX - 163006209 163006222 3.0E-06 ATGAATAATACATC 14 POU4F1_POU_DBD_monomeric_14_1 SELEX + 163006210 163006223 5.0E-06 ATGTATTATTCATT 14 HMX1_homeodomain_DBD_monomeric_11_1 SELEX - 163010475 163010485 7.0E-06 AACGATTAAAA 11 V_RUSH1A_02_M01107 TRANSFAC + 163010372 163010381 6.0E-06 ATACTTATAA 10 V_FOXP1_01_M00987 TRANSFAC - 163006005 163006024 8.0E-06 GTATTTTAAATGTTGATTGT 20 V_FOXP1_01_M00987 TRANSFAC + 163006219 163006238 5.0E-06 TCATTTATATTTTAAATAGT 20 V_DBX1_01_M01483 TRANSFAC + 163006105 163006121 1.0E-05 CTTTCAATTAATAGTCC 17 V_DBX1_01_M01483 TRANSFAC - 163006212 163006228 9.0E-06 ATATAAATGAATAATAC 17 V_DBX1_01_M01483 TRANSFAC + 163006215 163006231 5.0E-06 TTATTCATTTATATTTT 17 V_DBX1_01_M01483 TRANSFAC - 163006216 163006232 5.0E-06 TAAAATATAAATGAATA 17 V_DBX1_01_M01483 TRANSFAC - 163010471 163010487 9.0E-06 AAAACGATTAAAAATAT 17 V_FREAC7_01_M00293 TRANSFAC - 163006216 163006231 5.0E-06 AAAATATAAATGAATA 16 V_FREAC7_01_M00293 TRANSFAC + 163010373 163010388 8.0E-06 TACTTATAAATACGGT 16 V_APOLYA_B_M00310 TRANSFAC + 163006141 163006155 7.0E-06 ATTATACTGCATTTC 15 V_POU3F3_01_M03090 TRANSFAC - 163006211 163006227 1.0E-06 TATAAATGAATAATACA 17 V_XFD1_01_M00267 TRANSFAC + 163010375 163010388 5.0E-06 CTTATAAATACGGT 14 V_NF1_Q6_01_M00806 TRANSFAC - 163010299 163010315 3.0E-06 CTGGTAGAGTGCCAAGA 17 V_EVI1_04_M00081 TRANSFAC - 163005744 163005758 7.0E-06 TGACATGTTTAAAAA 15 V_EVI1_04_M00081 TRANSFAC - 163006216 163006230 2.0E-06 AAATATAAATGAATA 15 V_BCL6_01_M01183 TRANSFAC + 163006216 163006231 1.0E-06 TATTCATTTATATTTT 16 V_MMEF2_Q6_M00405 TRANSFAC - 163005739 163005754 1.0E-06 ATGTTTAAAAATCCTT 16 V_MEF2_02_M00231 TRANSFAC + 163006102 163006123 8.0E-06 TGGCTTTCAATTAATAGTCCTT 22 V_OCTAMER_01_M01324 TRANSFAC - 163006211 163006227 1.0E-06 TATAAATGAATAATACA 17 V_POU1F1_Q6_M00744 TRANSFAC - 163006213 163006222 1.0E-06 ATGAATAATA 10 V_HOXC4_01_M01369 TRANSFAC - 163006308 163006324 9.0E-06 CCCTTTAATTTAGAACA 17 V_NERF_Q2_M00531 TRANSFAC - 163010289 163010306 4.0E-06 TGCCAAGAAGCAGGTCTC 18 V_COUPTF_Q6_M01036 TRANSFAC - 163010317 163010339 7.0E-06 TTCTCTGCTCTTTCACCCCCTCT 23 V_SOX21_03_M02803 TRANSFAC + 163006218 163006233 6.0E-06 TTCATTTATATTTTAA 16 V_SOX21_03_M02803 TRANSFAC - 163006218 163006233 7.0E-06 TTAAAATATAAATGAA 16 V_TCFAP2E_04_M02926 TRANSFAC + 163006319 163006332 8.0E-06 AAAGGGAAAAAATC 14 V_TCFAP2E_04_M02926 TRANSFAC - 163013905 163013918 6.0E-06 AGCTTGAAGAAAAA 10 V_CDX_Q5_M00991 TRANSFAC - 163006222 163006239 6.0E-06 CACTATTTAAAATATAAA 18 V_CDX_Q5_M00991 TRANSFAC - 163010375 163010392 7.0E-06 TATTACCGTATTTATAAG 18 V_HELIOSA_01_M01003 TRANSFAC + 163006318 163006328 9.0E-06 TAAAGGGAAAA 11 V_MEF2A_Q6_M02024 TRANSFAC - 163006014 163006023 7.0E-06 TATTTTAAAT 10 V_MEF2A_Q6_M02024 TRANSFAC + 163006226 163006235 7.0E-06 TATTTTAAAT 10 V_MEF2A_Q6_M02024 TRANSFAC - 163006227 163006236 9.0E-06 TATTTAAAAT 10 V_MEF2A_Q6_M02024 TRANSFAC + 163010472 163010481 4.0E-06 TATTTTTAAT 10 V_HNF6_Q6_M00639 TRANSFAC - 163010405 163010416 6.0E-06 TTAAATCAATCC 12 V_ELF4_04_M02850 TRANSFAC - 163006219 163006235 5.0E-06 ATTTAAAATATAAATGA 17 V_ZNF219_01_M01122 TRANSFAC + 163006082 163006093 2.0E-06 CACCCCCCTCAC 12 V_POU3F2_01_M00463 TRANSFAC - 163010408 163010421 5.0E-06 ATACATTAAATCAA 14 V_MYF_01_M01302 TRANSFAC + 163012207 163012218 0.0E+00 AAGCAACAGCTG 12 V_ZFP105_03_M02827 TRANSFAC + 163006004 163006018 7.0E-06 CACAATCAACATTTA 15 V_GFI1_01_M00250 TRANSFAC - 163010398 163010421 6.0E-06 ATACATTAAATCAATCCACTCTTT 24 V_NKX61_01_M00424 TRANSFAC - 163006106 163006118 9.0E-06 CTATTAATTGAAA 13 V_MRF2_01_M00454 TRANSFAC + 163006014 163006027 8.0E-06 ATTTAAAATACCCA 14 V_IRX4_01_M01410 TRANSFAC + 163006007 163006023 4.0E-06 AATCAACATTTAAAATA 17 V_AMEF2_Q6_M00403 TRANSFAC + 163005648 163005665 7.0E-06 AGCATTACAAATAATCCA 18 V_HOXA3_07_M02869 TRANSFAC - 163010475 163010488 3.0E-06 CAAAACGATTAAAA 14 V_IRF3_Q3_M01279 TRANSFAC - 163006319 163006331 4.0E-06 ATTTTTTCCCTTT 13 V_MEF2_03_M00232 TRANSFAC - 163006104 163006125 7.0E-06 TGAAGGACTATTAATTGAAAGC 22 V_MEF2_03_M00232 TRANSFAC + 163006221 163006242 5.0E-06 ATTTATATTTTAAATAGTGTAA 22 V_NKX52_01_M01315 TRANSFAC - 163010472 163010488 7.0E-06 CAAAACGATTAAAAATA 17 V_SFPI1_04_M02896 TRANSFAC + 163012201 163012214 9.0E-06 AAAATTAAGCAACA 14 V_IRF3_06_M02871 TRANSFAC + 163010334 163010347 4.0E-06 AGAGAAAGGTGTCA 14 V_OCT1_04_M00138 TRANSFAC - 163006128 163006150 1.0E-06 GCAGTATAATGTAAATGCTTGGA 23 V_OCT1_04_M00138 TRANSFAC - 163006208 163006230 1.0E-06 AAATATAAATGAATAATACATCT 23 V_OCT1_04_M00138 TRANSFAC + 163006213 163006235 1.0E-06 TATTATTCATTTATATTTTAAAT 23 V_OCT1_04_M00138 TRANSFAC - 163006214 163006236 2.0E-06 TATTTAAAATATAAATGAATAAT 23 V_HBP1_03_M02762 TRANSFAC - 163006214 163006229 2.0E-06 AATATAAATGAATAAT 16 V_AP4_Q5_M00175 TRANSFAC - 163012211 163012220 8.0E-06 GTCAGCTGTT 10 V_CDC5_01_M00478 TRANSFAC - 163010471 163010482 1.0E-05 GATTAAAAATAT 12 V_NKX3A_01_M00451 TRANSFAC - 163010370 163010381 0.0E+00 TTATAAGTATTA 12 V_NCX_02_M01420 TRANSFAC - 163010471 163010487 3.0E-06 AAAACGATTAAAAATAT 17 V_MAFK_Q3_M02022 TRANSFAC - 163012213 163012223 9.0E-06 TGAGTCAGCTG 11 V_ARID3A_04_M02735 TRANSFAC + 163006104 163006120 4.0E-06 GCTTTCAATTAATAGTC 17 V_STAF_02_M00264 TRANSFAC + 163006068 163006088 8.0E-06 CTTATCCATCATGCCACCCCC 21 V_TBP_06_M02814 TRANSFAC + 163006218 163006233 2.0E-06 TTCATTTATATTTTAA 16 V_TBP_06_M02814 TRANSFAC - 163006218 163006233 5.0E-06 TTAAAATATAAATGAA 16 V_TBP_06_M02814 TRANSFAC - 163006220 163006235 4.0E-06 ATTTAAAATATAAATG 16 V_IRX3_01_M01318 TRANSFAC + 163006007 163006023 7.0E-06 AATCAACATTTAAAATA 17 V_NR1B1_Q6_M02110 TRANSFAC - 163006301 163006310 9.0E-06 ACAGGTCAAA 10 V_TBX5_01_M01019 TRANSFAC + 163010338 163010349 3.0E-06 AAAGGTGTCAAG 12 V_LIM1_01_M01418 TRANSFAC - 163006103 163006119 9.0E-06 ACTATTAATTGAAAGCC 17 V_GATA4_Q3_M00632 TRANSFAC + 163006314 163006325 7.0E-06 AAATTAAAGGGA 12 V_OTX2_Q3_M01719 TRANSFAC - 163010475 163010487 2.0E-06 AAAACGATTAAAA 13 V_CIZ_01_M00734 TRANSFAC + 163006324 163006332 2.0E-06 GAAAAAATC 9 V_TBP_01_M00471 TRANSFAC + 163010377 163010384 4.0E-06 TATAAATA 8 V_AP3_Q6_M00690 TRANSFAC + 163006311 163006318 5.0E-06 TCTAAATT 8 V_HOXB8_01_M01451 TRANSFAC + 163006104 163006119 7.0E-06 GCTTTCAATTAATAGT 16 V_FOXL1_02_M02857 TRANSFAC - 163006221 163006236 5.0E-06 TATTTAAAATATAAAT 16 V_GFI1B_01_M01058 TRANSFAC - 163010404 163010415 5.0E-06 TAAATCAATCCA 12 V_HDX_01_M01333 TRANSFAC + 163006322 163006338 2.0E-06 GGGAAAAAATCATTTTA 17 V_AIRE_01_M00999 TRANSFAC - 163006114 163006139 1.0E-06 TAAATGCTTGGAAGTGAAGGACTATT 26 V_LMX1B_01_M01363 TRANSFAC + 163006103 163006119 9.0E-06 GGCTTTCAATTAATAGT 17 V_LMX1B_01_M01363 TRANSFAC + 163006225 163006241 8.0E-06 ATATTTTAAATAGTGTA 17 V_PBX1_02_M00124 TRANSFAC - 163010401 163010415 9.0E-06 TAAATCAATCCACTC 15 V_PLZF_02_M01075 TRANSFAC - 163006209 163006237 2.0E-06 CTATTTAAAATATAAATGAATAATACATC 29 V_PLZF_02_M01075 TRANSFAC + 163006212 163006240 3.0E-06 GTATTATTCATTTATATTTTAAATAGTGT 29 V_SIX4_01_M01374 TRANSFAC - 163010336 163010352 8.0E-06 AGGCTTGACACCTTTCT 17 V_ZFP281_01_M01597 TRANSFAC + 163005714 163005724 9.0E-06 TGGGGGTAGGG 11 V_MEF3_B_M00319 TRANSFAC + 163006171 163006183 3.0E-06 GCCTCAGGCTACA 13 V_BBX_03_M02739 TRANSFAC + 163006215 163006229 9.0E-06 TTATTCATTTATATT 15 V_BBX_03_M02739 TRANSFAC - 163006215 163006229 6.0E-06 AATATAAATGAATAA 15 V_SOX8_03_M02808 TRANSFAC + 163006208 163006224 1.0E-06 AGATGTATTATTCATTT 17 V_SRF_06_M02916 TRANSFAC - 163013899 163013915 1.0E-05 TTGAAGAAAAAAAGTCT 16 V_SRF_06_M02916 TRANSFAC - 163013900 163013916 2.0E-06 CTTGAAGAAAAAAAGTC 15 V_SRF_06_M02916 TRANSFAC - 163013901 163013917 7.0E-06 GCTTGAAGAAAAAAAGT 14 V_FOXJ2_01_M00422 TRANSFAC - 163006215 163006232 9.0E-06 TAAAATATAAATGAATAA 18 V_SOX18_04_M02905 TRANSFAC + 163012179 163012194 3.0E-06 ATACGGAATTCATACA 16 V_SATB1_01_M01232 TRANSFAC + 163005650 163005661 1.0E-05 CATTACAAATAA 12 V_HOXD8_01_M01432 TRANSFAC - 163006216 163006232 7.0E-06 TAAAATATAAATGAATA 17 V_HOMEZ_01_M01429 TRANSFAC + 163006325 163006341 2.0E-06 AAAAAATCATTTTAAAG 17 V_LHX9_01_M01367 TRANSFAC - 163006103 163006119 6.0E-06 ACTATTAATTGAAAGCC 17 V_BARHL2_01_M01446 TRANSFAC - 163010474 163010489 7.0E-06 CCAAAACGATTAAAAA 16 V_PIT1_Q6_M00802 TRANSFAC + 163006216 163006233 0.0E+00 TATTCATTTATATTTTAA 18 V_PIT1_Q6_M00802 TRANSFAC + 163012185 163012202 3.0E-06 AATTCATACAGCAACAAA 18 V_SRY_05_M02917 TRANSFAC + 163012162 163012178 2.0E-06 AAAGAAAACAATTTGTG 17 V_MEF2A_05_M01301 TRANSFAC - 163006015 163006026 2.0E-06 GGGTATTTTAAA 12 V_HMEF2_Q6_M00406 TRANSFAC + 163006013 163006028 5.0E-06 CATTTAAAATACCCAC 16 V_LHX5_01_M01353 TRANSFAC - 163006103 163006119 4.0E-06 ACTATTAATTGAAAGCC 17 V_CEBP_Q2_01_M00912 TRANSFAC - 163012202 163012213 8.0E-06 GTTGCTTAATTT 12 V_BRN3C_01_M01408 TRANSFAC - 163006215 163006230 6.0E-06 AAATATAAATGAATAA 16 V_HMX3_02_M01413 TRANSFAC - 163010472 163010488 6.0E-06 CAAAACGATTAAAAATA 17 V_ZFP128_04_M02932 TRANSFAC + 163010369 163010382 8.0E-06 GTAATACTTATAAA 14 V_ZFP128_04_M02932 TRANSFAC - 163010369 163010382 7.0E-06 TTTATAAGTATTAC 14 V_AP2ALPHA_03_M01047 TRANSFAC + 163006168 163006182 7.0E-06 GCAGCCTCAGGCTAC 15 V_AP2ALPHA_03_M01047 TRANSFAC - 163006168 163006182 7.0E-06 GTAGCCTGAGGCTGC 15 V_PAX4_04_M00380 TRANSFAC - 163006197 163006226 9.0E-06 ATAAATGAATAATACATCTGAACCGACAGC 30 V_OCT4_01_M01125 TRANSFAC - 163006008 163006022 1.0E-05 ATTTTAAATGTTGAT 15 V_OCT4_01_M01125 TRANSFAC - 163006135 163006149 3.0E-06 CAGTATAATGTAAAT 15 V_ER_Q6_M00191 TRANSFAC + 163006292 163006310 2.0E-06 TTAGGGTGCTTTGACCTGT 19

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.