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SACS Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 26278 spastic ataxia of Charlevoix-Saguenay (sacsin) chr13 - 24007341 - 24012841 24007841 Transcription Factor Binding Sites   Download all TFBS in the SACS promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints MYF6_bHLH_full_dimeric_10_1 SELEX + 24004948 24004957 9.0E-06 AACAAATGTT 10 Myc_MA0147.1 JASPAR + 24006922 24006931 9.0E-06 AGCACGTGGA 10 ESR2_MA0258.1 JASPAR - 24006687 24006704 1.0E-06 CAGGGTCATGATGTCCCA 18 LHX2_homeodomain_DBD_dimeric_15_1 SELEX - 24010738 24010752 8.0E-06 TTATTATGGAAATTG 15 Mafb_bZIP_DBD_monomeric_12_1 SELEX + 24010948 24010959 0.0E+00 AATATGCTGACT 12 POU1F1_POU_DBD_monomeric_14_1 SELEX - 24010737 24010750 2.0E-06 ATTATGGAAATTGG 14 POU2F2_POU_DBD_monomeric_11_1 SELEX - 24010739 24010749 3.0E-06 TTATGGAAATT 11 FOXD2_forkhead_DBD_dimeric_14_1 SELEX + 24004948 24004961 1.0E-05 AACAAATGTTTGTC 14 FOXD2_forkhead_DBD_dimeric_14_1 SELEX - 24004948 24004961 1.0E-05 GACAAACATTTGTT 14 NR2F1_MA0017.1 JASPAR + 24007738 24007751 4.0E-06 GGAACCTTGGACTT 14 ZIC4_C2H2_DBD_monomeric_15_1 SELEX + 24007337 24007351 3.0E-06 GACCCCACGCTGTGT 15 RFX2_RFX_DBD_dimeric_15_1 SELEX - 24007374 24007388 6.0E-06 GGTTGCCAGGCACCG 15 T_MA0009.1 JASPAR + 24007931 24007941 3.0E-06 TTAGGTGTCAA 11 POU3F3_POU_DBD_monomeric_13_1 SELEX - 24010738 24010750 2.0E-06 ATTATGGAAATTG 13 HOXD8_homeodomain_DBD_monomeric_10_1 SELEX - 24008021 24008030 9.0E-06 AAAAATTAGC 10 znf143_MA0088.1 JASPAR - 24006653 24006672 2.0E-06 GACCATCCAGACTGCCTTCC 20 RFX3_RFX_DBD_dimeric_15_1 SELEX - 24007374 24007388 7.0E-06 GGTTGCCAGGCACCG 15 NRL_bZIP_DBD_monomeric_11_1 SELEX + 24010948 24010958 0.0E+00 AATATGCTGAC 11 RFX4_RFX_DBD_dimeric_15_1 SELEX - 24007374 24007388 4.0E-06 GGTTGCCAGGCACCG 15 TBX2_TBX_full_monomeric_11_1 SELEX + 24007932 24007942 6.0E-06 TAGGTGTCAAT 11 POU3F1_POU_DBD_monomeric_12_1 SELEX - 24010738 24010749 4.0E-06 TTATGGAAATTG 12 Foxd3_MA0041.1 JASPAR + 24004951 24004962 1.0E-05 AAATGTTTGTCT 12 Pou5f1_MA0142.1 JASPAR - 24007398 24007412 1.0E-06 CTTTGTCATTTTAAT 15 Pou5f1_MA0142.1 JASPAR - 24010740 24010754 2.0E-06 ATTTATTATGGAAAT 15 Myf_MA0055.1 JASPAR + 24007618 24007629 1.0E-06 AAGCAGCTGCAG 12 PPARG_MA0066.1 JASPAR - 24006685 24006704 2.0E-06 CAGGGTCATGATGTCCCAGT 20 HNF4A_MA0114.1 JASPAR - 24010587 24010599 4.0E-06 AGGCCAAAGGCCT 13 POU2F1_POU_DBD_monomeric_12_1 SELEX - 24010739 24010750 1.0E-06 ATTATGGAAATT 12 GBX2_homeodomain_DBD_dimeric_14_1 SELEX + 24007316 24007329 1.0E-06 TTATTGTTCAATAA 14 GBX2_homeodomain_DBD_dimeric_14_1 SELEX - 24007316 24007329 1.0E-06 TTATTGAACAATAA 14 MAFK_bZIP_full_monomeric_12_1 SELEX + 24010947 24010958 2.0E-06 CAATATGCTGAC 12 THRB_nuclearreceptor_DBD_dimeric_19_1 SELEX + 24008080 24008098 7.0E-06 GTGACCTTAGACAAGTCAC 19 THRB_nuclearreceptor_DBD_dimeric_19_1 SELEX - 24008080 24008098 3.0E-06 GTGACTTGTCTAAGGTCAC 19 POU3F2_POU_DBD_monomeric_12_1 SELEX - 24010738 24010749 4.0E-06 TTATGGAAATTG 12 Sox2_MA0143.1 JASPAR - 24007399 24007413 2.0E-06 GCTTTGTCATTTTAA 15 ZIC1_C2H2_full_monomeric_14_1 SELEX + 24007337 24007350 3.0E-06 GACCCCACGCTGTG 14 V_MINI20_B_M00324 TRANSFAC + 24007608 24007628 4.0E-06 TACCTCCCCCAAGCAGCTGCA 21 V_MTF1_01_M01242 TRANSFAC - 24011024 24011043 6.0E-06 GTGAGCAGAGCTTTGGCCAC 20 V_TCF3_01_M01594 TRANSFAC - 24007401 24007413 8.0E-06 GCTTTGTCATTTT 13 V_TCF3_01_M01594 TRANSFAC + 24007783 24007795 1.0E-06 CCTTTGTTTTCCT 13 V_TCF3_01_M01594 TRANSFAC + 24007890 24007902 8.0E-06 CCTTTTTTTTTCT 13 V_AML_Q6_M00769 TRANSFAC - 24011053 24011067 1.0E-05 AACCATGTGGTCTCC 15 V_APOLYA_B_M00310 TRANSFAC + 24008064 24008078 2.0E-06 ATTAAACACCAGTTG 15 V_OBOX5_05_M03066 TRANSFAC - 24010745 24010761 6.0E-06 AGAAGGGATTTATTATG 17 V_MAFK_03_M02776 TRANSFAC + 24010946 24010960 1.0E-06 GCAATATGCTGACTC 15 V_PAX4_03_M00378 TRANSFAC - 24007389 24007400 1.0E-06 AATTTCCACCCG 12 V_SOX30_03_M02804 TRANSFAC - 24007312 24007327 3.0E-06 ATTGAACAATAAGATG 16 V_FOXD3_01_M00130 TRANSFAC + 24004951 24004962 7.0E-06 AAATGTTTGTCT 12 V_MAFB_05_M02775 TRANSFAC + 24010947 24010963 4.0E-06 CAATATGCTGACTCCTT 17 V_FOXO4_02_M00476 TRANSFAC + 24007783 24007796 7.0E-06 CCTTTGTTTTCCTC 14 V_POU5F1_02_M02245 TRANSFAC - 24007398 24007412 1.0E-06 CTTTGTCATTTTAAT 15 V_POU5F1_02_M02245 TRANSFAC - 24010740 24010754 2.0E-06 ATTTATTATGGAAAT 15 V_HOXA13_02_M01297 TRANSFAC + 24006675 24006683 8.0E-06 AAGTAAAAC 9 V_SPDEF_04_M02915 TRANSFAC - 24010601 24010616 0.0E+00 GTGTAAATCCTAGTAG 16 V_OCT1_01_M00135 TRANSFAC - 24010735 24010753 4.0E-06 TTTATTATGGAAATTGGCT 19 V_AP2_Q6_01_M00915 TRANSFAC + 24007692 24007704 1.0E-06 CCGTCCCCAGGCC 13 V_HNF4A_03_M02220 TRANSFAC - 24010587 24010599 4.0E-06 AGGCCAAAGGCCT 13 V_HFH4_01_M00742 TRANSFAC - 24004946 24004958 3.0E-06 AAACATTTGTTTT 13 V_HTF_01_M00538 TRANSFAC + 24007984 24008007 9.0E-06 AACCAACCACACGTTTTTGTTCTC 24 V_NFAT2_01_M01748 TRANSFAC - 24010739 24010747 5.0E-06 ATGGAAATT 9 V_TCFAP2E_04_M02926 TRANSFAC - 24007892 24007905 4.0E-06 AGAAGAAAAAAAAA 14 V_TCFAP2E_04_M02926 TRANSFAC - 24007893 24007906 1.0E-06 AAGAAGAAAAAAAA 14 V_MEF2A_Q6_M02024 TRANSFAC + 24004941 24004950 5.0E-06 TATTTAAAAC 10 V_MYC_01_M02250 TRANSFAC + 24006922 24006931 9.0E-06 AGCACGTGGA 10 V_TST1_01_M00133 TRANSFAC + 24007393 24007407 6.0E-06 TGGAAATTAAAATGA 15 V_SOX13_03_M02797 TRANSFAC + 24004943 24004958 9.0E-06 TTTAAAACAAATGTTT 16 V_SOX13_03_M02797 TRANSFAC - 24007313 24007328 1.0E-06 TATTGAACAATAAGAT 16 V_SOX7_03_M02807 TRANSFAC + 24004941 24004962 5.0E-06 TATTTAAAACAAATGTTTGTCT 22 V_SOX7_03_M02807 TRANSFAC - 24007309 24007330 1.0E-06 CTTATTGAACAATAAGATGGGA 22 V_OBOX5_02_M01480 TRANSFAC - 24010745 24010761 6.0E-06 AGAAGGGATTTATTATG 17 V_MYF_01_M01302 TRANSFAC + 24007618 24007629 1.0E-06 AAGCAGCTGCAG 12 V_COUP_01_M00158 TRANSFAC + 24007738 24007751 4.0E-06 GGAACCTTGGACTT 14 V_HNF1_Q6_M00790 TRANSFAC + 24008019 24008036 2.0E-06 AGGCTAATTTTTAGCAGT 18 V_CMYC_01_M01145 TRANSFAC - 24006921 24006932 7.0E-06 ATCCACGTGCTT 12 V_POLY_C_M00212 TRANSFAC + 24006675 24006692 7.0E-06 AAGTAAAACTACTGGGAC 18 MYC_MAX_MA0059.1 JASPAR + 24006921 24006931 4.0E-06 AAGCACGTGGA 11 V_HNF1_Q6_01_M01011 TRANSFAC - 24008017 24008037 1.0E-06 TACTGCTAAAAATTAGCCTTT 21 V_SOX18_03_M02801 TRANSFAC - 24004942 24004957 5.0E-06 AACATTTGTTTTAAAT 16 V_SOX18_03_M02801 TRANSFAC + 24007314 24007329 2.0E-06 TCTTATTGTTCAATAA 16 V_USF_02_M00122 TRANSFAC + 24011017 24011030 3.0E-06 ATATCACGTGGCCA 14 V_USF_02_M00122 TRANSFAC - 24011017 24011030 3.0E-06 TGGCCACGTGATAT 14 V_OCT1_04_M00138 TRANSFAC - 24010733 24010755 8.0E-06 GATTTATTATGGAAATTGGCTCA 23 V_USF_01_M00121 TRANSFAC + 24011017 24011030 3.0E-06 ATATCACGTGGCCA 14 V_USF_01_M00121 TRANSFAC - 24011017 24011030 3.0E-06 TGGCCACGTGATAT 14 V_PPARG_03_M00528 TRANSFAC - 24010587 24010603 8.0E-06 TAGAAGGCCAAAGGCCT 17 V_MEF2_Q6_01_M00941 TRANSFAC + 24008058 24008069 9.0E-06 GGCTCTATTAAA 12 V_STAT4_Q5_M02117 TRANSFAC + 24007589 24007598 2.0E-06 TTAAAGGAAA 10 V_TBP_06_M02814 TRANSFAC + 24004937 24004952 1.0E-05 AGAATATTTAAAACAA 16 V_OCT4_02_M01124 TRANSFAC - 24007397 24007411 1.0E-06 TTTGTCATTTTAATT 15 V_SOX11_03_M02795 TRANSFAC - 24007779 24007795 2.0E-06 AGGAAAACAAAGGCCGA 17 V_TBX5_01_M01019 TRANSFAC + 24007931 24007942 3.0E-06 TTAGGTGTCAAT 12 V_SOX9_B1_M00410 TRANSFAC - 24007314 24007327 4.0E-06 ATTGAACAATAAGA 14 V_FOXO1_Q5_M01216 TRANSFAC - 24007785 24007793 5.0E-06 GAAAACAAA 9 V_GLI3_01_M01596 TRANSFAC - 24007725 24007735 1.0E-05 CTGGGTGGCCA 11 V_ZFP105_04_M02931 TRANSFAC + 24007318 24007334 2.0E-06 ATTGTTCAATAAGACTC 17 V_ZFP105_04_M02931 TRANSFAC + 24007933 24007949 3.0E-06 AGGTGTCAATAATGCTG 17 V_MINI19_B_M00323 TRANSFAC + 24007608 24007628 6.0E-06 TACCTCCCCCAAGCAGCTGCA 21 V_SOX15_03_M02799 TRANSFAC - 24007312 24007328 0.0E+00 TATTGAACAATAAGATG 17 V_MTF1_06_M02882 TRANSFAC + 24004940 24004953 6.0E-06 ATATTTAAAACAAA 14 V_MTF1_06_M02882 TRANSFAC - 24007894 24007907 2.0E-06 TAAGAAGAAAAAAA 14 V_T3R_01_M00239 TRANSFAC - 24008076 24008091 2.0E-06 GTCTAAGGTCACACAA 16 V_IPF1_05_M01255 TRANSFAC + 24007394 24007405 5.0E-06 GGAAATTAAAAT 12 V_FOXL1_02_M02857 TRANSFAC + 24004941 24004956 4.0E-06 TATTTAAAACAAATGT 16 V_FOXL1_02_M02857 TRANSFAC + 24007396 24007411 8.0E-06 AAATTAAAATGACAAA 16 V_DOBOX5_01_M01463 TRANSFAC - 24010745 24010761 0.0E+00 AGAAGGGATTTATTATG 17 V_PADS_C_M00211 TRANSFAC - 24011054 24011062 4.0E-06 TGTGGTCTC 9 V_OTX2_01_M01387 TRANSFAC - 24010745 24010761 1.0E-06 AGAAGGGATTTATTATG 17 V_PLZF_02_M01075 TRANSFAC + 24004956 24004984 9.0E-06 TTTGTCTGGATGTAAGGTTATTATAATTG 29 V_SIX4_01_M01374 TRANSFAC - 24007929 24007945 2.0E-06 ATTATTGACACCTAAGG 17 V_SOX21_04_M02907 TRANSFAC + 24007313 24007329 2.0E-06 ATCTTATTGTTCAATAA 17 V_HSF_Q6_M00641 TRANSFAC + 24010922 24010934 2.0E-06 GTCCAGAGGTTTC 13 V_OCT1_07_M00248 TRANSFAC - 24007397 24007408 8.0E-06 GTCATTTTAATT 12 V_OCT1_07_M00248 TRANSFAC - 24010739 24010750 1.0E-06 ATTATGGAAATT 12 V_SOX8_03_M02808 TRANSFAC + 24007312 24007328 4.0E-06 CATCTTATTGTTCAATA 17 V_SOX2_01_M02246 TRANSFAC - 24007399 24007413 2.0E-06 GCTTTGTCATTTTAA 15 V_SRF_06_M02916 TRANSFAC + 24004942 24004958 8.0E-06 ATTTAAAACAAATGTTT 17 V_SRF_06_M02916 TRANSFAC - 24007888 24007904 2.0E-06 GAAGAAAAAAAAAGGCT 17 V_SRF_06_M02916 TRANSFAC - 24007889 24007905 4.0E-06 AGAAGAAAAAAAAAGGC 17 V_SRF_06_M02916 TRANSFAC - 24007892 24007908 4.0E-06 TTAAGAAGAAAAAAAAA 17 V_FOXJ2_01_M00422 TRANSFAC - 24004949 24004966 4.0E-06 ATCCAGACAAACATTTGT 18 V_FOXO1_04_M01969 TRANSFAC + 24007669 24007688 5.0E-06 GCCAACAACACCATGGAGCC 20 V_SOX4_01_M01308 TRANSFAC - 24007783 24007790 1.0E-05 AACAAAGG 8 V_RFX3_05_M02892 TRANSFAC + 24011043 24011065 6.0E-06 CATGTGGCCTGGAGACCACATGG 23 V_HOXB3_01_M01330 TRANSFAC + 24007517 24007533 6.0E-06 AGAGCTCATTACTCACA 17 V_PAX4_02_M00377 TRANSFAC - 24008021 24008031 7.0E-06 TAAAAATTAGC 11 V_PITX2_01_M01447 TRANSFAC - 24010745 24010761 1.0E-06 AGAAGGGATTTATTATG 17 V_SOX12_03_M02796 TRANSFAC - 24004942 24004955 5.0E-06 CATTTGTTTTAAAT 14 V_SOX12_03_M02796 TRANSFAC + 24007316 24007329 1.0E-06 TTATTGTTCAATAA 14 V_SOX12_03_M02796 TRANSFAC + 24007997 24008010 7.0E-06 TTTTTGTTCTCTTC 14 V_PIT1_Q6_M00802 TRANSFAC + 24010756 24010773 1.0E-06 CCTTCTTACATATCTATA 18 V_SRY_05_M02917 TRANSFAC - 24007313 24007329 1.0E-06 TTATTGAACAATAAGAT 17 V_MEF2_01_M00006 TRANSFAC - 24008019 24008034 2.0E-06 TGCTAAAAATTAGCCT 16 V_HMEF2_Q6_M00406 TRANSFAC - 24008019 24008034 1.0E-05 TGCTAAAAATTAGCCT 16 V_OBOX5_01_M01381 TRANSFAC - 24010745 24010761 1.0E-06 AGAAGGGATTTATTATG 17 V_TCF3_05_M02920 TRANSFAC + 24007391 24007405 9.0E-06 GGTGGAAATTAAAAT 15 V_ATATA_B_M00311 TRANSFAC + 24006952 24006961 9.0E-06 TTACTTAAGC 10 V_OTX1_01_M01366 TRANSFAC - 24010745 24010761 1.0E-06 AGAAGGGATTTATTATG 17 V_OBOX6_06_M03067 TRANSFAC + 24010745 24010761 1.0E-06 CATAATAAATCCCTTCT 17 V_SMAD1_01_M01590 TRANSFAC - 24007782 24007793 3.0E-06 GAAAACAAAGGC 12 V_SMAD1_01_M01590 TRANSFAC - 24007895 24007906 7.0E-06 AAGAAGAAAAAA 12 V_SOX9_Q4_M01284 TRANSFAC - 24007781 24007791 1.0E-06 AAACAAAGGCC 11 V_ESR2_01_M02377 TRANSFAC - 24006687 24006704 1.0E-06 CAGGGTCATGATGTCCCA 18 V_NANOG_02_M01247 TRANSFAC + 24007399 24007418 1.0E-06 TTAAAATGACAAAGCGGCTA 20 V_NANOG_02_M01247 TRANSFAC - 24007891 24007910 4.0E-06 CTTTAAGAAGAAAAAAAAAG 20 V_OCT4_01_M01125 TRANSFAC - 24007398 24007412 1.0E-06 CTTTGTCATTTTAAT 15 V_OCT4_01_M01125 TRANSFAC - 24010740 24010754 1.0E-06 ATTTATTATGGAAAT 15

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