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Construction and Validation

Optimal Promoter Size

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AMBN Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 258 chr4 + 71452974 - 71462974 0 Transcription Factor Binding Sites   Download all TFBS in the AMBN promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints FOXO4_forkhead_DBD_dimeric_14_1 SELEX + 71460112 71460125 1.0E-05 GCAAATATGTTGAG 14 FOXO4_forkhead_DBD_dimeric_14_1 SELEX - 71460112 71460125 9.0E-06 CTCAACATATTTGC 14 Ascl2_bHLH_DBD_dimeric_10_1 SELEX + 71460124 71460133 6.0E-06 AGCAGCTGCC 10 FOXO1_forkhead_DBD_dimeric_14_1 SELEX - 71460112 71460125 4.0E-06 CTCAACATATTTGC 14 V_CEBP_01_M00159 TRANSFAC - 71460106 71460118 4.0E-06 TATTTGCTAAATG 13 V_POLY_C_M00212 TRANSFAC - 71460076 71460093 7.0E-06 AAATAAAGTTTTTGTGAT 18 V_OCAB_Q6_M02113 TRANSFAC - 71460100 71460110 1.0E-05 AAATGCATATA 11 V_OCT1_06_M00162 TRANSFAC - 71460060 71460073 6.0E-06 CAGAATTGCATGCT 14 V_GATA5_03_M02756 TRANSFAC - 71460068 71460084 5.0E-06 TTTTGTGATAACAGAAT 17

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