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BACE1 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 23621 beta-site APP-cleaving enzyme 1 chr11 - 117186472 - 117191972 117186972 Transcription Factor Binding Sites   Download all TFBS in the BACE1 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints TBX21_TBX_full_dimeric_16_1 SELEX - 117190378 117190393 6.0E-06 GGCGTGAACTATCACA 16 FOXJ2_forkhead_DBD_dimeric_13_1 SELEX + 117190311 117190323 6.0E-06 AAAAACAACAATA 13 Rxrb_nuclearreceptor_DBD_dimeric_14_1 SELEX - 117183998 117184011 9.0E-06 GGGCTTAAAGTTCA 14 MSX2_homeodomain_DBD_dimeric_18_1 SELEX + 117184048 117184065 2.0E-06 ACATTTATTGAGCAATTA 18 BARX1_homeodomain_DBD_dimeric_17_1 SELEX + 117184049 117184065 3.0E-06 CATTTATTGAGCAATTA 17 POU3F2_POU_DBD_monomeric_13_1 SELEX - 117190261 117190273 4.0E-06 TTTGCATTTTTAA 13 TBX5_TBX_DBD_dimeric_20_1 SELEX + 117190375 117190394 0.0E+00 GGGTGTGATAGTTCACGCCT 20 TBX5_TBX_DBD_dimeric_20_1 SELEX - 117190375 117190394 0.0E+00 AGGCGTGAACTATCACACCC 20 EWSR1-FLI1_MA0149.1 JASPAR + 117185653 117185670 3.0E-06 GGGAGAAGGGGAGGAGGA 18 IRF7_IRF_DBD_trimeric_17_1 SELEX - 117186991 117187007 5.0E-06 AAAGCGAAAACCTTTTG 17 Pax4_MA0068.1 JASPAR - 117190193 117190222 4.0E-06 AATAATTTACAGTCCAAACAATACCTTCAC 30 Pax4_MA0068.1 JASPAR - 117190194 117190223 2.0E-06 GAATAATTTACAGTCCAAACAATACCTTCA 30 NR2F1_MA0017.1 JASPAR + 117183998 117184011 4.0E-06 TGAACTTTAAGCCC 14 IRF1_MA0050.1 JASPAR - 117186997 117187008 2.0E-06 AAAAGCGAAAAC 12 POU3F3_POU_DBD_monomeric_13_1 SELEX + 117190255 117190267 8.0E-06 AATATGTTAAAAA 13 SP1_MA0079.2 JASPAR - 117185623 117185632 3.0E-06 CCCCTCCCCC 10 SP1_MA0079.2 JASPAR - 117185665 117185674 9.0E-06 CCCCTCCTCC 10 POU2F3_POU_DBD_dimeric_12_1 SELEX + 117190261 117190272 7.0E-06 TTAAAAATGCAA 12 MGA_TBX_DBD_dimeric_18_2 SELEX + 117190376 117190393 0.0E+00 GGTGTGATAGTTCACGCC 18 MGA_TBX_DBD_dimeric_18_2 SELEX - 117190376 117190393 0.0E+00 GGCGTGAACTATCACACC 18 TBX4_TBX_DBD_dimeric_20_1 SELEX + 117190375 117190394 0.0E+00 GGGTGTGATAGTTCACGCCT 20 TBX4_TBX_DBD_dimeric_20_1 SELEX - 117190375 117190394 0.0E+00 AGGCGTGAACTATCACACCC 20 Msx3_homeodomain_DBD_dimeric_18_1 SELEX + 117184048 117184065 1.0E-06 ACATTTATTGAGCAATTA 18 Foxd3_MA0041.1 JASPAR - 117190312 117190323 3.0E-06 TATTGTTGTTTT 12 MGA_TBX_DBD_dimeric_18_1 SELEX + 117190377 117190394 4.0E-06 GTGTGATAGTTCACGCCT 18 MGA_TBX_DBD_dimeric_18_1 SELEX - 117190377 117190394 4.0E-06 AGGCGTGAACTATCACAC 18 EN1_homeodomain_full_dimeric_14_1 SELEX + 117184052 117184065 2.0E-06 TTATTGAGCAATTA 14 EN1_homeodomain_full_dimeric_14_1 SELEX - 117184052 117184065 0.0E+00 TAATTGCTCAATAA 14 TBX2_TBX_full_dimeric_18_1 SELEX + 117190376 117190393 0.0E+00 GGTGTGATAGTTCACGCC 18 TBX2_TBX_full_dimeric_18_1 SELEX - 117190376 117190393 0.0E+00 GGCGTGAACTATCACACC 18 POU3F1_POU_DBD_monomeric_12_2 SELEX - 117190261 117190272 9.0E-06 TTGCATTTTTAA 12 POU5F1P1_POU_DBD_monomeric_12_1 SELEX + 117190261 117190272 8.0E-06 TTAAAAATGCAA 12 Pou5f1_MA0142.1 JASPAR + 117190251 117190265 5.0E-06 TATTAATATGTTAAA 15 POU2F1_POU_DBD_monomeric_12_1 SELEX + 117190255 117190266 1.0E-05 AATATGTTAAAA 12 TEAD1_TEA_full_dimeric_17_1 SELEX - 117190254 117190270 8.0E-06 GCATTTTTAACATATTA 17 HNF4A_nuclearreceptor_full_dimeric_14_1 SELEX - 117183998 117184011 8.0E-06 GGGCTTAAAGTTCA 14 GBX2_homeodomain_DBD_dimeric_14_1 SELEX + 117184052 117184065 0.0E+00 TTATTGAGCAATTA 14 GBX2_homeodomain_DBD_dimeric_14_1 SELEX - 117184052 117184065 0.0E+00 TAATTGCTCAATAA 14 MSX1_homeodomain_DBD_dimeric_18_1 SELEX + 117184048 117184065 1.0E-06 ACATTTATTGAGCAATTA 18 Sox2_MA0143.1 JASPAR + 117190250 117190264 1.0E-05 CTATTAATATGTTAA 15 RXRA_nuclearreceptor_full_dimeric_14_1 SELEX - 117183998 117184011 6.0E-06 GGGCTTAAAGTTCA 14 Foxj3_forkhead_DBD_dimeric_13_1 SELEX + 117190311 117190323 2.0E-06 AAAAACAACAATA 13 POU4F1_POU_DBD_monomeric_14_1 SELEX - 117190259 117190272 9.0E-06 TTGCATTTTTAACA 14 RREB1_MA0073.1 JASPAR - 117185607 117185626 9.0E-06 CCCCACCCCACACCTCCCCA 20 RREB1_MA0073.1 JASPAR - 117185608 117185627 7.0E-06 CCCCCACCCCACACCTCCCC 20 IRF2_MA0051.1 JASPAR - 117186992 117187009 3.0E-06 GAAAAGCGAAAACCTTTT 18 V_FOXP1_01_M00987 TRANSFAC + 117190202 117190221 5.0E-06 TTGTTTGGACTGTAAATTAT 20 V_FOXP1_01_M00987 TRANSFAC - 117190299 117190318 7.0E-06 TTGTTTTTGTTGGAAAGGGT 20 V_FOXP1_01_M00987 TRANSFAC - 117190487 117190506 2.0E-06 TTATTTTTGGTTTTGCTTAA 20 V_HNF3B_01_M00131 TRANSFAC - 117190314 117190328 9.0E-06 TGAAATATTGTTGTT 15 V_STAT5A_Q6_M01890 TRANSFAC + 117190288 117190300 9.0E-06 GCATTTCTAGGAC 13 V_BCL6_Q3_01_M02085 TRANSFAC - 117184021 117184030 0.0E+00 CTTTCTAGAA 10 V_BCL6_Q3_01_M02085 TRANSFAC + 117190290 117190299 5.0E-06 ATTTCTAGGA 10 V_CDX2_Q5_01_M01659 TRANSFAC - 117184048 117184058 7.0E-06 TCAATAAATGT 11 V_MAFK_03_M02776 TRANSFAC + 117190262 117190276 8.0E-06 TAAAAATGCAAACTC 15 V_EVI1_04_M00081 TRANSFAC + 117190254 117190268 6.0E-06 TAATATGTTAAAAAT 15 V_FOXD3_01_M00130 TRANSFAC - 117190312 117190323 5.0E-06 TATTGTTGTTTT 12 V_HP1SITEFACTOR_Q6_M00725 TRANSFAC - 117190211 117190222 2.0E-06 AATAATTTACAG 12 V_FOXO4_02_M00476 TRANSFAC - 117190308 117190321 3.0E-06 TTGTTGTTTTTGTT 14 V_STAT_Q6_M00777 TRANSFAC + 117190287 117190299 7.0E-06 GGCATTTCTAGGA 13 V_POU5F1_02_M02245 TRANSFAC + 117190251 117190265 5.0E-06 TATTAATATGTTAAA 15 V_SOX5_01_M00042 TRANSFAC - 117190199 117190208 7.0E-06 CAAACAATAC 10 V_CEBP_Q2_M00190 TRANSFAC - 117184052 117184065 3.0E-06 TAATTGCTCAATAA 14 V_MAF_Q6_M00648 TRANSFAC - 117184007 117184022 3.0E-06 AAGAGGAAAGTGGGCT 16 V_SP1_03_M02281 TRANSFAC - 117185623 117185632 3.0E-06 CCCCTCCCCC 10 V_SP1_03_M02281 TRANSFAC - 117185665 117185674 9.0E-06 CCCCTCCTCC 10 V_HFH4_01_M00742 TRANSFAC - 117190360 117190372 4.0E-06 CTTCATTTGTTTT 13 V_DLX2_01_M01468 TRANSFAC - 117184054 117184069 4.0E-06 AGAGTAATTGCTCAAT 16 V_CDX_Q5_M00991 TRANSFAC + 117187230 117187247 3.0E-06 GATACAGAGAGAAATAAA 18 V_RPC155_01_M01798 TRANSFAC + 117190441 117190456 0.0E+00 CCAGGAGTTCAAGACC 16 V_SRF_C_M00215 TRANSFAC + 117190222 117190236 5.0E-06 TCCATTTTTGGAGAG 15 V_ELF4_04_M02850 TRANSFAC + 117190303 117190319 3.0E-06 TTTCCAACAAAAACAAC 17 V_SOX13_03_M02797 TRANSFAC + 117190312 117190327 2.0E-06 AAAACAACAATATTTC 16 V_ZNF219_01_M01122 TRANSFAC - 117185618 117185629 1.0E-05 CTCCCCCACCCC 12 V_GC_01_M00255 TRANSFAC + 117185622 117185635 5.0E-06 TGGGGGAGGGGCCG 14 V_ZFP105_03_M02827 TRANSFAC + 117190310 117190324 1.0E-06 CAAAAACAACAATAT 15 V_FOXO1_02_M00474 TRANSFAC - 117190308 117190321 9.0E-06 TTGTTGTTTTTGTT 14 V_COUP_01_M00158 TRANSFAC + 117183998 117184011 4.0E-06 TGAACTTTAAGCCC 14 V_IRF2_01_M00063 TRANSFAC - 117186997 117187009 1.0E-06 GAAAAGCGAAAAC 13 V_HES1_Q2_M01009 TRANSFAC + 117190430 117190444 2.0E-06 ATCGCTTGTGGCCAG 15 V_KROX_Q6_M00982 TRANSFAC - 117185618 117185631 8.0E-06 CCCTCCCCCACCCC 14 V_ZBP89_Q4_M01816 TRANSFAC - 117185622 117185631 4.0E-06 CCCTCCCCCA 10 V_IRX4_01_M01410 TRANSFAC + 117190251 117190267 2.0E-06 TATTAATATGTTAAAAA 17 V_SP1_Q6_M00196 TRANSFAC + 117185622 117185634 7.0E-06 TGGGGGAGGGGCC 13 V_FOXK1_04_M02856 TRANSFAC + 117190309 117190323 5.0E-06 ACAAAAACAACAATA 15 V_FOXK1_04_M02856 TRANSFAC + 117190312 117190326 1.0E-06 AAAACAACAATATTT 15 V_HOXB6_01_M01460 TRANSFAC + 117184054 117184069 1.0E-05 ATTGAGCAATTACTCT 16 V_IRF3_Q3_M01279 TRANSFAC + 117186995 117187007 9.0E-06 AGGTTTTCGCTTT 13 V_MAZ_Q6_01_M02023 TRANSFAC + 117185662 117185675 4.0E-06 GGAGGAGGAGGGGA 14 V_BCL6_Q3_M01171 TRANSFAC + 117190290 117190299 5.0E-06 ATTTCTAGGA 10 V_SOX18_03_M02801 TRANSFAC - 117190311 117190326 1.0E-05 AAATATTGTTGTTTTT 16 V_SOX18_03_M02801 TRANSFAC - 117190356 117190371 5.0E-06 TTCATTTGTTTTGAAT 16 V_NFE4_Q5_M02105 TRANSFAC - 117187065 117187076 5.0E-06 ACCCCTCTCCAG 12 V_OCT1_04_M00138 TRANSFAC + 117190250 117190272 6.0E-06 CTATTAATATGTTAAAAATGCAA 23 V_RREB1_01_M00257 TRANSFAC - 117185613 117185626 4.0E-06 CCCCACCCCACACC 14 V_SRF_03_M01304 TRANSFAC - 117190222 117190234 3.0E-06 CTCCAAAAATGGA 13 V_IRX5_01_M01472 TRANSFAC + 117190251 117190267 5.0E-06 TATTAATATGTTAAAAA 17 V_FOXO1_Q5_M01216 TRANSFAC + 117190311 117190319 5.0E-06 AAAAACAAC 9 V_FOXO1_Q5_M01216 TRANSFAC + 117190359 117190367 8.0E-06 CAAAACAAA 9 V_SP4_Q5_M01273 TRANSFAC - 117185623 117185633 5.0E-06 GCCCCTCCCCC 11 V_ZFP105_04_M02931 TRANSFAC - 117184047 117184063 5.0E-06 ATTGCTCAATAAATGTC 17 V_POU5F1_01_M01307 TRANSFAC + 117190266 117190275 9.0E-06 AATGCAAACT 10 V_CEBPA_01_M00116 TRANSFAC - 117184052 117184065 2.0E-06 TAATTGCTCAATAA 14 V_FOXL1_02_M02857 TRANSFAC + 117190355 117190370 7.0E-06 GATTCAAAACAAATGA 16 V_OCT1_Q6_M00195 TRANSFAC - 117190236 117190250 9.0E-06 GGCATTGCAAATTAC 15 V_FOXJ3_06_M02855 TRANSFAC + 117190354 117190370 8.0E-06 GGATTCAAAACAAATGA 17 V_BDP1_01_M01796 TRANSFAC - 117190445 117190456 2.0E-06 GGTCTTGAACTC 12 V_FPM315_01_M01587 TRANSFAC + 117185659 117185670 2.0E-06 AGGGGAGGAGGA 12 V_FPM315_01_M01587 TRANSFAC + 117185662 117185673 4.0E-06 GGAGGAGGAGGG 12 V_FOXO3_01_M00477 TRANSFAC - 117190308 117190321 3.0E-06 TTGTTGTTTTTGTT 14 V_PITX2_Q2_M00482 TRANSFAC + 117190394 117190404 3.0E-06 TGTAATCCAAG 11 V_PLZF_02_M01075 TRANSFAC + 117190202 117190230 2.0E-06 TTGTTTGGACTGTAAATTATTCCATTTTT 29 V_ZFP281_01_M01597 TRANSFAC + 117185622 117185632 1.0E-06 TGGGGGAGGGG 11 V_SRF_02_M01257 TRANSFAC - 117190217 117190234 3.0E-06 CTCCAAAAATGGAATAAT 18 V_SOX8_03_M02808 TRANSFAC - 117190312 117190328 3.0E-06 TGAAATATTGTTGTTTT 17 V_DMRT2_01_M01147 TRANSFAC + 117190214 117190229 1.0E-06 TAAATTATTCCATTTT 16 V_SOX2_01_M02246 TRANSFAC + 117190250 117190264 1.0E-05 CTATTAATATGTTAA 15 V_ZFP281_04_M02831 TRANSFAC - 117185620 117185634 3.0E-06 GGCCCCTCCCCCACC 15 V_EWSR1FLI1_01_M02252 TRANSFAC + 117185653 117185670 3.0E-06 GGGAGAAGGGGAGGAGGA 18 V_YY1_01_M00059 TRANSFAC + 117190218 117190234 9.0E-06 TTATTCCATTTTTGGAG 17 V_IRF1_01_M00062 TRANSFAC - 117186997 117187009 0.0E+00 GAAAAGCGAAAAC 13 V_PAX4_02_M00377 TRANSFAC - 117190213 117190223 3.0E-06 GAATAATTTAC 11 V_BSX_01_M01442 TRANSFAC - 117184054 117184069 7.0E-06 AGAGTAATTGCTCAAT 16 V_SOX12_03_M02796 TRANSFAC - 117190311 117190324 7.0E-06 ATATTGTTGTTTTT 14 V_UF1H3BETA_Q6_M01068 TRANSFAC + 117185620 117185633 0.0E+00 GGTGGGGGAGGGGC 14 V_RXRLXRB_01_M01198 TRANSFAC - 117183998 117184010 5.0E-06 GGCTTAAAGTTCA 13 V_CEBP_Q2_01_M00912 TRANSFAC - 117184052 117184063 4.0E-06 ATTGCTCAATAA 12 V_SP1_Q4_01_M00932 TRANSFAC + 117185622 117185634 8.0E-06 TGGGGGAGGGGCC 13 V_BARX1_01_M01340 TRANSFAC - 117184054 117184069 0.0E+00 AGAGTAATTGCTCAAT 16 V_CEBPA_Q6_M01866 TRANSFAC + 117184052 117184064 1.0E-06 TTATTGAGCAATT 13 V_NANOG_02_M01247 TRANSFAC + 117190355 117190374 4.0E-06 GATTCAAAACAAATGAAGCT 20 V_OCT4_01_M01125 TRANSFAC + 117190251 117190265 2.0E-06 TATTAATATGTTAAA 15

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