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SPPL2C Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 162540 signal peptide peptidase like 2C chr17 - 43917255 - 43922755 43917755 Transcription Factor Binding Sites   Download all TFBS in the SPPL2C promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints NFE2_bZIP_DBD_dimeric_11_1 SELEX + 43919680 43919690 6.0E-06 AATGAGTCACC 11 NFE2_bZIP_DBD_dimeric_11_1 SELEX - 43919680 43919690 9.0E-06 GGTGACTCATT 11 HSF2_HSF_DBD_trimeric_13_1 SELEX - 43918605 43918617 1.0E-06 TTCCAGAACTTTT 13 SOX10_HMG_full_dimeric_14_1 SELEX + 43919643 43919656 5.0E-06 TGAAAATTCAGTCT 14 POU2F1_POU_DBD_dimeric_14_1 SELEX + 43919641 43919654 1.0E-05 TATGAAAATTCAGT 14 POU2F1_POU_DBD_dimeric_14_1 SELEX - 43919641 43919654 6.0E-06 ACTGAATTTTCATA 14 Tp53_p53l_DBD_dimeric_18_1 SELEX - 43919525 43919542 3.0E-06 ACATGTTCAGGAACAAAT 18 ZNF713_C2H2_full_monomeric_17_1 SELEX - 43918776 43918792 7.0E-06 AAGACGCCAGACACAAA 17 SOX21_HMG_DBD_dimeric_13_2 SELEX + 43918903 43918915 1.0E-06 TGAATGCTATTCC 13 SOX21_HMG_DBD_dimeric_13_2 SELEX - 43918903 43918915 3.0E-06 GGAATAGCATTCA 13 SRY_HMG_DBD_dimeric_13_2 SELEX + 43918903 43918915 7.0E-06 TGAATGCTATTCC 13 SRY_HMG_DBD_dimeric_13_2 SELEX - 43918903 43918915 2.0E-06 GGAATAGCATTCA 13 FOXC1_forkhead_DBD_monomeric_11_1 SELEX + 43919724 43919734 6.0E-06 AGTGTAAATAA 11 Lhx8_homeodomain_DBD_dimeric_12_1 SELEX + 43919560 43919571 5.0E-06 TCATTGTAATTA 12 Lhx8_homeodomain_DBD_dimeric_12_1 SELEX - 43919560 43919571 4.0E-06 TAATTACAATGA 12 POU1F1_POU_DBD_monomeric_14_1 SELEX - 43918792 43918805 9.0E-06 ATTATGCTAAATGA 14 SOX8_HMG_DBD_dimeric_14_1 SELEX + 43919643 43919656 3.0E-06 TGAAAATTCAGTCT 14 SOX15_HMG_full_dimeric_15_3 SELEX - 43918902 43918916 5.0E-06 GGGAATAGCATTCAG 15 POU2F2_POU_DBD_monomeric_11_1 SELEX - 43918794 43918804 6.0E-06 TTATGCTAAAT 11 ISX_homeodomain_DBD_dimeric_13_1 SELEX + 43919577 43919589 4.0E-06 GTAATCTAACTAA 13 FOXD2_forkhead_DBD_dimeric_14_1 SELEX + 43919690 43919703 3.0E-06 CAAAAATATTGGCA 14 BARHL2_homeodomain_full_dimeric_16_1 SELEX + 43918745 43918760 2.0E-06 TAAGTGGAATTAATCG 16 Barhl1_homeodomain_DBD_dimeric_16_1 SELEX + 43918745 43918760 2.0E-06 TAAGTGGAATTAATCG 16 REL_MA0101.1 JASPAR - 43918637 43918646 3.0E-06 TGGGATTTCC 10 POU3F3_POU_DBD_monomeric_13_1 SELEX - 43918793 43918805 4.0E-06 ATTATGCTAAATG 13 FOXD3_forkhead_DBD_dimeric_14_1 SELEX + 43919690 43919703 5.0E-06 CAAAAATATTGGCA 14 SOX2_HMG_full_dimeric_15_1 SELEX - 43918902 43918916 1.0E-06 GGGAATAGCATTCAG 15 RELA_MA0107.1 JASPAR - 43918637 43918646 7.0E-06 TGGGATTTCC 10 Pou2f2_POU_DBD_dimeric_14_1 SELEX + 43919641 43919654 7.0E-06 TATGAAAATTCAGT 14 Pou2f2_POU_DBD_dimeric_14_1 SELEX - 43919641 43919654 4.0E-06 ACTGAATTTTCATA 14 SP1_MA0079.2 JASPAR + 43918671 43918680 3.0E-06 CCCCTCCCCC 10 NFIX_NFI_full_monomeric_9_2 SELEX - 43919697 43919705 8.0E-06 TTTGCCAAT 9 FOXC1_forkhead_DBD_dimeric_14_1 SELEX + 43919690 43919703 5.0E-06 CAAAAATATTGGCA 14 FOXC1_forkhead_DBD_dimeric_14_1 SELEX - 43919690 43919703 5.0E-06 TGCCAATATTTTTG 14 SOX9_HMG_full_dimeric_16_3 SELEX + 43919642 43919657 2.0E-06 ATGAAAATTCAGTCTA 16 SOX14_HMG_DBD_dimeric_15_1 SELEX - 43918902 43918916 1.0E-06 GGGAATAGCATTCAG 15 VENTX_homeodomain_DBD_dimeric_21_1 SELEX + 43918799 43918819 4.0E-06 GCATAATGTGTTTCCACTTAG 21 VENTX_homeodomain_DBD_dimeric_21_1 SELEX - 43918801 43918821 5.0E-06 TGCTAAGTGGAAACACATTAT 21 POU3F1_POU_DBD_monomeric_12_1 SELEX - 43918793 43918804 9.0E-06 TTATGCTAAATG 12 POU3F1_POU_DBD_monomeric_12_1 SELEX + 43919640 43919651 7.0E-06 TTATGAAAATTC 12 FOXC2_forkhead_DBD_dimeric_14_1 SELEX + 43919690 43919703 7.0E-06 CAAAAATATTGGCA 14 Nkx3-2_MA0122.1 JASPAR - 43918811 43918819 8.0E-06 CTAAGTGGA 9 JDP2_bZIP_full_dimeric_9_1 SELEX + 43919681 43919689 1.0E-05 ATGAGTCAC 9 Pou5f1_MA0142.1 JASPAR + 43919635 43919649 6.0E-06 GTTTCTTATGAAAAT 15 POU2F1_POU_DBD_monomeric_12_1 SELEX - 43918794 43918805 2.0E-06 ATTATGCTAAAT 12 POU2F1_POU_DBD_monomeric_12_1 SELEX - 43918814 43918825 5.0E-06 ATTATGCTAAGT 12 Tp53_p53l_DBD_dimeric_17_1 SELEX + 43919537 43919553 3.0E-06 ACATGTTTCTGACAGTT 17 LHX6_homeodomain_full_dimeric_12_1 SELEX + 43919560 43919571 7.0E-06 TCATTGTAATTA 12 Sox3_HMG_DBD_dimeric_17_3 SELEX + 43918901 43918917 1.0E-05 GCTGAATGCTATTCCCT 17 GBX2_homeodomain_DBD_dimeric_14_1 SELEX + 43919695 43919708 9.0E-06 ATATTGGCAAATTA 14 FOXB1_forkhead_full_monomeric_9_1 SELEX + 43919726 43919734 4.0E-06 TGTAAATAA 9 POU3F2_POU_DBD_monomeric_12_1 SELEX - 43918793 43918804 9.0E-06 TTATGCTAAATG 12 POU3F2_POU_DBD_monomeric_12_1 SELEX + 43919640 43919651 6.0E-06 TTATGAAAATTC 12 FOXB1_forkhead_DBD_monomeric_11_1 SELEX + 43919724 43919734 3.0E-06 AGTGTAAATAA 11 Sox1_HMG_DBD_dimeric_15_2 SELEX - 43918902 43918916 1.0E-06 GGGAATAGCATTCAG 15 V_NFKAPPAB65_01_M00052 TRANSFAC - 43918637 43918646 4.0E-06 TGGGATTTCC 10 V_MEIS1BHOXA9_02_M00421 TRANSFAC - 43918875 43918888 1.0E-05 TGACGTTTTGATAC 14 V_TGIF_01_M00418 TRANSFAC - 43919543 43919553 7.0E-06 AACTGTCAGAA 11 V_AP1_Q2_M00173 TRANSFAC - 43919680 43919690 5.0E-06 GGTGACTCATT 11 V_FOXP3_Q4_M00992 TRANSFAC + 43918771 43918787 6.0E-06 GTCCTTTTGTGTCTGGC 17 V_TCFE2A_04_M02927 TRANSFAC - 43926427 43926443 6.0E-06 CAGGCCAGATGGCCACT 17 V_DLX3_01_M01400 TRANSFAC + 43919560 43919576 8.0E-06 TCATTGTAATTACTGTC 17 V_EVI1_04_M00081 TRANSFAC + 43918598 43918612 4.0E-06 AGATAGAAAAAGTTC 15 V_POU5F1_02_M02245 TRANSFAC + 43919635 43919649 6.0E-06 GTTTCTTATGAAAAT 15 V_OCT1_Q5_01_M00930 TRANSFAC - 43919641 43919651 7.0E-06 GAATTTTCATA 11 V_OTX_Q1_M01117 TRANSFAC - 43918752 43918759 5.0E-06 GATTAATT 8 V_OCT1_01_M00135 TRANSFAC - 43918790 43918808 4.0E-06 CACATTATGCTAAATGAAG 19 V_OCT1_01_M00135 TRANSFAC - 43918810 43918828 7.0E-06 CACATTATGCTAAGTGGAA 19 V_OCT1_01_M00135 TRANSFAC - 43918830 43918848 9.0E-06 AACATTATGCTAAGCCGAA 19 V_FOXO3A_Q1_M01137 TRANSFAC + 43919726 43919737 3.0E-06 TGTAAATAACTG 12 V_AP2_Q6_01_M00915 TRANSFAC + 43926453 43926465 1.0E-05 CCCTCCGCAGGCC 13 V_SP1_03_M02281 TRANSFAC + 43918671 43918680 3.0E-06 CCCCTCCCCC 10 V_SPZ1_01_M00446 TRANSFAC - 43918643 43918657 7.0E-06 ACTGGTGGGTATGGG 15 V_HOXC6_01_M01406 TRANSFAC - 43919560 43919576 9.0E-06 GACAGTAATTACAATGA 17 V_AP1_Q6_M00174 TRANSFAC - 43919680 43919690 1.0E-06 GGTGACTCATT 11 V_TCF3_04_M02816 TRANSFAC - 43919656 43919672 6.0E-06 TATCCTTCAAAGCATTA 17 V_HOXA6_01_M01392 TRANSFAC - 43919560 43919575 8.0E-06 ACAGTAATTACAATGA 16 V_XFD3_01_M00269 TRANSFAC + 43919682 43919695 7.0E-06 TGAGTCACCAAAAA 14 V_XFD3_01_M00269 TRANSFAC + 43919724 43919737 5.0E-06 AGTGTAAATAACTG 14 V_CREL_01_M00053 TRANSFAC - 43918637 43918646 3.0E-06 TGGGATTTCC 10 V_ZBED6_01_M01598 TRANSFAC - 43919379 43919390 1.0E-06 GAGGCTCGCCTG 12 V_ZBP89_Q4_M01816 TRANSFAC + 43918672 43918681 4.0E-06 CCCTCCCCCA 10 V_AP1_Q4_M00188 TRANSFAC - 43919680 43919690 5.0E-06 GGTGACTCATT 11 V_HOXB6_01_M01460 TRANSFAC + 43919560 43919575 2.0E-06 TCATTGTAATTACTGT 16 V_MAZ_Q6_01_M02023 TRANSFAC - 43918667 43918680 3.0E-06 GGGGGAGGGGAGAA 14 V_AP2BETA_Q3_M01858 TRANSFAC - 43926455 43926470 8.0E-06 GCCAGGGCCTGCGGAG 16 V_OCT1_05_M00161 TRANSFAC + 43918832 43918845 3.0E-06 CGGCTTAGCATAAT 14 V_CDX2_Q5_M00729 TRANSFAC + 43919589 43919602 5.0E-06 AATGTTATATTACT 14 V_JUNDM2_04_M02876 TRANSFAC + 43919677 43919692 4.0E-06 ACAAATGAGTCACCAA 16 V_JUNDM2_04_M02876 TRANSFAC - 43919678 43919693 4.0E-06 TTTGGTGACTCATTTG 16 V_OCT1_04_M00138 TRANSFAC + 43919634 43919656 5.0E-06 TGTTTCTTATGAAAATTCAGTCT 23 V_RREB1_01_M00257 TRANSFAC + 43926598 43926611 8.0E-06 CCCCACATCCCCCA 14 V_STAF_02_M00264 TRANSFAC - 43926542 43926562 1.0E-06 CCTTCCCATCGGGCCTGGCAG 21 V_AP1_01_M00517 TRANSFAC + 43919679 43919691 6.0E-06 AAATGAGTCACCA 13 V_IRX3_01_M01318 TRANSFAC + 43919583 43919599 6.0E-06 TAACTAAATGTTATATT 17 V_OCT4_02_M01124 TRANSFAC + 43919636 43919650 1.0E-06 TTTCTTATGAAAATT 15 V_AP1_Q2_01_M00924 TRANSFAC - 43919677 43919688 5.0E-06 TGACTCATTTGT 12 V_OCT_Q6_M00795 TRANSFAC - 43919641 43919651 1.0E-05 GAATTTTCATA 11 V_TFIII_Q6_M00706 TRANSFAC - 43919387 43919395 6.0E-06 AGAGGGAGG 9 V_NEUROD_02_M01288 TRANSFAC - 43926337 43926348 5.0E-06 CAGCTGCTGTGT 12 V_NEUROD_02_M01288 TRANSFAC + 43926495 43926506 6.0E-06 CTGCTGCTGGCC 12 V_DLX7_01_M01486 TRANSFAC + 43919560 43919576 2.0E-06 TCATTGTAATTACTGTC 17 V_HOXB7_01_M01396 TRANSFAC + 43919562 43919577 1.0E-05 ATTGTAATTACTGTCG 16 V_LRH1_Q5_M01142 TRANSFAC - 43918848 43918859 1.0E-05 TGGACCTTGAAA 12 V_MTF1_06_M02882 TRANSFAC - 43919632 43919645 9.0E-06 TCATAAGAAACATC 14 V_CEBPA_01_M00116 TRANSFAC + 43919695 43919708 6.0E-06 ATATTGGCAAATTA 14 V_EOMES_04_M02851 TRANSFAC + 43926395 43926410 5.0E-06 GCGGAGGTGTTGGCAG 16 V_AP1FJ_Q2_M00172 TRANSFAC - 43919680 43919690 4.0E-06 GGTGACTCATT 11 V_IPF1_01_M01233 TRANSFAC - 43919565 43919574 8.0E-06 CAGTAATTAC 10 V_SMAD3_03_M02794 TRANSFAC - 43918775 43918791 7.0E-06 AGACGCCAGACACAAAA 17 V_TCF4_Q5_M00671 TRANSFAC + 43919421 43919428 1.0E-05 CCTTTGAA 8 V_ZFP281_01_M01597 TRANSFAC - 43918671 43918681 1.0E-06 TGGGGGAGGGG 11 V_OCT1_07_M00248 TRANSFAC + 43919559 43919570 9.0E-06 GTCATTGTAATT 12 V_HSF2_02_M01244 TRANSFAC + 43918605 43918617 8.0E-06 AAAAGTTCTGGAA 13 V_SIX6_01_M01345 TRANSFAC + 43918869 43918885 8.0E-06 TAGCAGGTATCAAAACG 17 V_NFE2_Q6_M02104 TRANSFAC + 43919680 43919695 6.0E-06 AATGAGTCACCAAAAA 16 V_UF1H3BETA_Q6_M01068 TRANSFAC - 43918670 43918683 2.0E-06 GCTGGGGGAGGGGA 14 V_IRXB3_01_M01377 TRANSFAC + 43919583 43919599 5.0E-06 TAACTAAATGTTATATT 17 V_IPF1_03_M01235 TRANSFAC - 43919565 43919574 7.0E-06 CAGTAATTAC 10 V_HOX13_02_M01452 TRANSFAC - 43919560 43919575 3.0E-06 ACAGTAATTACAATGA 16 V_OCT4_01_M01125 TRANSFAC + 43919635 43919649 7.0E-06 GTTTCTTATGAAAAT 15 V_HOXC8_01_M01321 TRANSFAC + 43919560 43919575 1.0E-06 TCATTGTAATTACTGT 16

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.