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KLB Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 152831 klotho beta chr4 + 39403472 - 39408972 39408472 Transcription Factor Binding Sites   Download all TFBS in the KLB promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints THRB_nuclearreceptor_DBD_dimeric_20_1 SELEX - 39403550 39403569 9.0E-06 GTGACGTGATCTCAGCTCAC 20 SOX21_HMG_DBD_dimeric_13_2 SELEX + 39408778 39408790 8.0E-06 TAAATGAAAGTCA 13 Arx_homeodomain_DBD_dimeric_13_1 SELEX - 39412245 39412257 8.0E-06 AATATCAAATTAA 13 SRY_HMG_DBD_dimeric_13_2 SELEX - 39408778 39408790 7.0E-06 TGACTTTCATTTA 13 POU5F1P1_POU_DBD_monomeric_9_1 SELEX - 39410743 39410751 2.0E-06 TATGCAAAT 9 ZNF75A_C2H2_DBD_monomeric_12_1 SELEX + 39412197 39412208 5.0E-06 GTTTTTCCCACT 12 POU2F3_POU_DBD_monomeric_9_1 SELEX - 39410743 39410751 2.0E-06 TATGCAAAT 9 POU1F1_POU_DBD_monomeric_14_1 SELEX - 39410740 39410753 0.0E+00 GATATGCAAATGAC 14 Rarb_nuclearreceptor_DBD_dimeric_18_1 SELEX - 39412290 39412307 9.0E-06 CTGGGTCACAAGGGGGCA 18 SOX15_HMG_full_dimeric_15_3 SELEX - 39408777 39408791 5.0E-06 CTGACTTTCATTTAC 15 POU2F2_POU_DBD_monomeric_11_1 SELEX + 39405961 39405971 6.0E-06 TTATGCTAAAT 11 POU2F2_POU_DBD_monomeric_11_1 SELEX - 39410742 39410752 0.0E+00 ATATGCAAATG 11 POU3F4_POU_DBD_monomeric_9_1 SELEX - 39410743 39410751 2.0E-06 TATGCAAAT 9 Pou2f2_POU_DBD_monomeric_9_1 SELEX - 39410743 39410751 2.0E-06 TATGCAAAT 9 FOXD2_forkhead_DBD_dimeric_14_1 SELEX + 39412237 39412250 2.0E-06 AGAAAACATTAATT 14 FOXD2_forkhead_DBD_dimeric_14_1 SELEX - 39412237 39412250 1.0E-06 AATTAATGTTTTCT 14 FOXD2_forkhead_DBD_dimeric_14_1 SELEX + 39412339 39412352 1.0E-06 CGAAAACATTTATT 14 FOXD2_forkhead_DBD_dimeric_14_1 SELEX - 39412339 39412352 5.0E-06 AATAAATGTTTTCG 14 POU3F3_POU_DBD_monomeric_13_1 SELEX + 39405960 39405972 1.0E-05 TTTATGCTAAATC 13 POU3F3_POU_DBD_monomeric_13_1 SELEX - 39410741 39410753 2.0E-06 GATATGCAAATGA 13 FOXD3_forkhead_DBD_dimeric_14_1 SELEX + 39412237 39412250 6.0E-06 AGAAAACATTAATT 14 FOXD3_forkhead_DBD_dimeric_14_1 SELEX - 39412237 39412250 1.0E-06 AATTAATGTTTTCT 14 FOXD3_forkhead_DBD_dimeric_14_1 SELEX + 39412339 39412352 1.0E-06 CGAAAACATTTATT 14 FOXD3_forkhead_DBD_dimeric_14_1 SELEX - 39412339 39412352 8.0E-06 AATAAATGTTTTCG 14 RARG_nuclearreceptor_DBD_dimeric_17_2 SELEX - 39412290 39412306 4.0E-06 TGGGTCACAAGGGGGCA 17 ALX3_homeodomain_full_dimeric_13_1 SELEX - 39412245 39412257 1.0E-05 AATATCAAATTAA 13 SOX2_HMG_full_dimeric_15_1 SELEX - 39408777 39408791 6.0E-06 CTGACTTTCATTTAC 15 HNF1A_homeodomain_full_dimeric_15_1 SELEX + 39408493 39408507 2.0E-06 AGCTAATCATTGACA 15 HNF1A_homeodomain_full_dimeric_15_1 SELEX - 39408493 39408507 1.0E-06 TGTCAATGATTAGCT 15 POU2F3_POU_DBD_dimeric_12_1 SELEX - 39408373 39408384 2.0E-06 ATGAAAATGCAT 12 FOXC1_forkhead_DBD_dimeric_14_1 SELEX - 39412237 39412250 8.0E-06 AATTAATGTTTTCT 14 FOXC1_forkhead_DBD_dimeric_14_1 SELEX + 39412339 39412352 7.0E-06 CGAAAACATTTATT 14 FOXC1_forkhead_DBD_dimeric_14_1 SELEX - 39412339 39412352 7.0E-06 AATAAATGTTTTCG 14 Alx4_homeodomain_DBD_dimeric_13_1 SELEX - 39412245 39412257 8.0E-06 AATATCAAATTAA 13 SOX9_HMG_full_dimeric_16_3 SELEX - 39408604 39408619 6.0E-06 AAGAAAATCCATTCAT 16 Lhx3_MA0135.1 JASPAR + 39412242 39412254 8.0E-06 ACATTAATTTGAT 13 SOX14_HMG_DBD_dimeric_15_1 SELEX - 39408777 39408791 4.0E-06 CTGACTTTCATTTAC 15 HNF1B_homeodomain_full_dimeric_13_1 SELEX + 39408494 39408506 2.0E-06 GCTAATCATTGAC 13 HNF1B_homeodomain_full_dimeric_13_1 SELEX - 39408494 39408506 2.0E-06 GTCAATGATTAGC 13 POU3F1_POU_DBD_monomeric_12_1 SELEX + 39405961 39405972 9.0E-06 TTATGCTAAATC 12 POU3F1_POU_DBD_monomeric_12_1 SELEX - 39410741 39410752 0.0E+00 ATATGCAAATGA 12 FOXC2_forkhead_DBD_dimeric_14_1 SELEX - 39412237 39412250 9.0E-06 AATTAATGTTTTCT 14 FOXC2_forkhead_DBD_dimeric_14_1 SELEX + 39412339 39412352 7.0E-06 CGAAAACATTTATT 14 FOXC2_forkhead_DBD_dimeric_14_1 SELEX - 39412339 39412352 7.0E-06 AATAAATGTTTTCG 14 Evi1_MA0029.1 JASPAR + 39408540 39408553 7.0E-06 TTGATAAGACAGTC 14 Hltf_MA0109.1 JASPAR + 39412342 39412351 1.0E-05 AAACATTTAT 10 ZNF282_C2H2_DBD_monomeric_17_1 SELEX + 39408808 39408824 6.0E-06 CTTTCCCTAAAAACTTT 17 DUXA_homeodomain_DBD_dimeric_13_1 SELEX + 39408490 39408502 9.0E-06 TCAAGCTAATCAT 13 TFAP4_bHLH_full_dimeric_10_1 SELEX - 39408787 39408796 5.0E-06 AACAGCTGAC 10 POU5F1P1_POU_DBD_monomeric_12_1 SELEX + 39408373 39408384 7.0E-06 ATGCATTTTCAT 12 POU5F1P1_POU_DBD_monomeric_12_1 SELEX - 39408373 39408384 1.0E-06 ATGAAAATGCAT 12 Myf_MA0055.1 JASPAR - 39408554 39408565 7.0E-06 CACCAACTGCTG 12 POU2F1_POU_DBD_monomeric_12_1 SELEX + 39405960 39405971 5.0E-06 TTTATGCTAAAT 12 POU2F1_POU_DBD_monomeric_12_1 SELEX - 39410742 39410753 1.0E-06 GATATGCAAATG 12 FOXI1_forkhead_full_dimeric_17_1 SELEX - 39412331 39412347 6.0E-06 ATGTTTTCGGTCTAAAA 17 SOX18_HMG_full_dimeric_15_3 SELEX - 39408604 39408618 9.0E-06 AGAAAATCCATTCAT 15 MAFK_bZIP_full_monomeric_12_1 SELEX - 39408692 39408703 3.0E-06 ATAAGTGCTGAC 12 HNF1B_homeodomain_full_dimeric_15_1 SELEX + 39408493 39408507 1.0E-06 AGCTAATCATTGACA 15 HNF1B_homeodomain_full_dimeric_15_1 SELEX - 39408493 39408507 1.0E-06 TGTCAATGATTAGCT 15 POU3F2_POU_DBD_monomeric_12_1 SELEX + 39405961 39405972 9.0E-06 TTATGCTAAATC 12 POU3F2_POU_DBD_monomeric_12_1 SELEX - 39410741 39410752 0.0E+00 ATATGCAAATGA 12 FOXO6_forkhead_DBD_dimeric_14_1 SELEX + 39412189 39412202 5.0E-06 GTGAACTTGTTTTT 14 Sox1_HMG_DBD_dimeric_15_2 SELEX - 39408777 39408791 2.0E-06 CTGACTTTCATTTAC 15 V_RUSH1A_02_M01107 TRANSFAC + 39412342 39412351 1.0E-05 AAACATTTAT 10 V_MEIS1BHOXA9_02_M00421 TRANSFAC - 39408682 39408695 7.0E-06 TGACAGGATGACAG 14 V_PREP1_01_M01459 TRANSFAC + 39408676 39408691 9.0E-06 AAAGATCTGTCATCCT 16 V_CDX2_Q5_01_M01659 TRANSFAC - 39412344 39412354 7.0E-06 TCAATAAATGT 11 V_OBOX5_05_M03066 TRANSFAC - 39403480 39403496 3.0E-06 AGCTGGGATTATTTAAA 17 V_ATF5_01_M01295 TRANSFAC + 39412276 39412286 7.0E-06 TTTCTTCCTTC 11 V_MAFK_03_M02776 TRANSFAC - 39408690 39408704 9.0E-06 AATAAGTGCTGACAG 15 V_HMGIY_Q3_M01010 TRANSFAC + 39408607 39408621 1.0E-06 AATGGATTTTCTTCA 15 V_BCL6_01_M01183 TRANSFAC + 39408378 39408393 7.0E-06 TTTTCATCTAATTTTT 16 V_BCL6_01_M01183 TRANSFAC - 39412157 39412172 7.0E-06 ATTGCAAGATTTCTTT 16 V_MAFB_05_M02775 TRANSFAC - 39408687 39408703 5.0E-06 ATAAGTGCTGACAGGAT 17 V_HOXA3_01_M00395 TRANSFAC + 39408762 39408770 7.0E-06 CCTAATTTT 9 V_CBF_02_M01080 TRANSFAC - 39408631 39408646 7.0E-06 TAGCGTGTGGTTATTT 16 V_PROP1_01_M01294 TRANSFAC + 39412246 39412256 8.0E-06 TAATTTGATAT 11 V_FOXJ2_02_M00423 TRANSFAC - 39412238 39412251 3.0E-06 AAATTAATGTTTTC 14 V_OCT1_Q5_01_M00930 TRANSFAC + 39410741 39410751 1.0E-06 TCATTTGCATA 11 V_OCT1_01_M00135 TRANSFAC + 39405957 39405975 6.0E-06 TCTTTTATGCTAAATCCTG 19 V_OCT1_01_M00135 TRANSFAC - 39410738 39410756 1.0E-06 AAAGATATGCAAATGACCT 19 V_EVI1_02_M00079 TRANSFAC + 39408541 39408551 4.0E-06 TGATAAGACAG 11 V_POU2F3_01_M01476 TRANSFAC - 39410739 39410754 2.0E-06 AGATATGCAAATGACC 16 V_OCT_C_M00210 TRANSFAC + 39410740 39410752 0.0E+00 GTCATTTGCATAT 13 V_PITX2_Q6_M02114 TRANSFAC + 39403484 39403493 6.0E-06 AATAATCCCA 10 V_LHX3_01_M01471 TRANSFAC + 39412241 39412257 5.0E-06 AACATTAATTTGATATT 17 V_AFP1_Q6_M00616 TRANSFAC - 39408383 39408393 9.0E-06 AAAAATTAGAT 11 V_PRX2_Q2_M02115 TRANSFAC - 39412245 39412253 2.0E-06 TCAAATTAA 9 V_NFAT2_01_M01748 TRANSFAC - 39408390 39408398 3.0E-06 ATGGAAAAA 9 V_TCFAP2E_04_M02926 TRANSFAC - 39408387 39408400 2.0E-06 TTATGGAAAAAATT 14 V_CDX_Q5_M00991 TRANSFAC + 39408500 39408517 1.0E-05 CATTGACAGAGCTTTACA 18 V_BARBIE_01_M00238 TRANSFAC - 39408519 39408533 8.0E-06 AGTAAAAGCTTGTGA 15 V_HNF1_C_M00206 TRANSFAC - 39408491 39408507 2.0E-06 TGTCAATGATTAGCTTG 17 V_OBOX5_02_M01480 TRANSFAC - 39403480 39403496 3.0E-06 AGCTGGGATTATTTAAA 17 V_HELIOSA_02_M01004 TRANSFAC - 39408390 39408400 1.0E-06 TTATGGAAAAA 11 V_FOXA2_02_M02853 TRANSFAC - 39412246 39412260 7.0E-06 TAAAATATCAAATTA 15 V_MYF_01_M01302 TRANSFAC - 39408554 39408565 7.0E-06 CACCAACTGCTG 12 V_DBX2_01_M01360 TRANSFAC - 39412238 39412253 9.0E-06 TCAAATTAATGTTTTC 16 V_HNF1_Q6_M00790 TRANSFAC + 39408492 39408509 4.0E-06 AAGCTAATCATTGACAGA 18 V_POLY_C_M00212 TRANSFAC - 39412336 39412353 7.0E-06 CAATAAATGTTTTCGGTC 18 V_ARID3A_02_M02839 TRANSFAC - 39412246 39412260 0.0E+00 TAAAATATCAAATTA 15 V_OCT1_05_M00161 TRANSFAC + 39410740 39410753 0.0E+00 GTCATTTGCATATC 14 V_IRF_Q6_M00772 TRANSFAC - 39408777 39408791 4.0E-06 CTGACTTTCATTTAC 15 V_LXR_DR4_Q3_M00766 TRANSFAC + 39412290 39412305 1.0E-06 TGCCCCCTTGTGACCC 16 V_SOX_Q6_M01014 TRANSFAC + 39408536 39408548 8.0E-06 AGCTTTGATAAGA 13 V_HBP1_03_M02762 TRANSFAC + 39408601 39408616 2.0E-06 GGAATGAATGGATTTT 16 V_AP4_Q5_M00175 TRANSFAC + 39408787 39408796 8.0E-06 GTCAGCTGTT 10 V_ERALPHA_01_M01801 TRANSFAC + 39403542 39403556 8.0E-06 AGGTTGAAGTGAGCT 15 V_OCAB_Q6_M02113 TRANSFAC + 39410743 39410753 2.0E-06 ATTTGCATATC 11 V_NCX_02_M01420 TRANSFAC - 39412239 39412255 7.0E-06 TATCAAATTAATGTTTT 17 V_ARID3A_04_M02735 TRANSFAC - 39403476 39403492 8.0E-06 GGGATTATTTAAACGCA 17 V_CTCF_02_M01259 TRANSFAC - 39412289 39412308 1.0E-05 TCTGGGTCACAAGGGGGCAG 20 V_OCT1_B_M00342 TRANSFAC - 39410742 39410751 2.0E-06 TATGCAAATG 10 V_ISGF4G_04_M02875 TRANSFAC + 39412237 39412250 3.0E-06 AGAAAACATTAATT 14 V_OCT_Q6_M00795 TRANSFAC + 39410741 39410751 0.0E+00 TCATTTGCATA 11 V_FOXO1_Q5_M01216 TRANSFAC - 39412194 39412202 8.0E-06 AAAAACAAG 9 V_SOX17_04_M02904 TRANSFAC + 39408373 39408389 1.0E-05 ATGCATTTTCATCTAAT 17 V_ZFP105_04_M02931 TRANSFAC - 39412343 39412359 7.0E-06 GTAGCTCAATAAATGTT 17 V_GFI1_Q6_M01067 TRANSFAC - 39412167 39412179 4.0E-06 CCAAATCATTGCA 13 V_CIZ_01_M00734 TRANSFAC - 39408387 39408395 5.0E-06 GAAAAAATT 9 V_MTF1_06_M02882 TRANSFAC - 39412245 39412258 8.0E-06 AAATATCAAATTAA 14 V_TAL1_01_M01591 TRANSFAC - 39408403 39408415 2.0E-06 TCTCCTTCTCTCT 13 V_IPF1_05_M01255 TRANSFAC + 39412240 39412251 1.0E-06 AAACATTAATTT 12 V_OCT2_01_M01368 TRANSFAC - 39410739 39410754 2.0E-06 AGATATGCAAATGACC 16 V_HNF1_01_M00132 TRANSFAC - 39412236 39412250 5.0E-06 AATTAATGTTTTCTA 15 V_OCT1_Q6_M00195 TRANSFAC - 39410740 39410754 0.0E+00 AGATATGCAAATGAC 15 V_LUN1_01_M00480 TRANSFAC + 39403489 39403505 4.0E-06 TCCCAGCTACTTGAGAG 17 V_CBF_01_M01079 TRANSFAC - 39408631 39408646 1.0E-06 TAGCGTGTGGTTATTT 16 V_LMX1B_01_M01363 TRANSFAC - 39412241 39412257 5.0E-06 AATATCAAATTAATGTT 17 V_DOBOX5_01_M01463 TRANSFAC - 39403480 39403496 1.0E-05 AGCTGGGATTATTTAAA 17 V_PITX2_Q2_M00482 TRANSFAC + 39403484 39403494 3.0E-06 AATAATCCCAG 11 V_PLZF_02_M01075 TRANSFAC + 39405955 39405983 7.0E-06 TGTCTTTTATGCTAAATCCTGGCATCATG 29 V_T3RBETA_Q6_01_M02119 TRANSFAC + 39403548 39403564 7.0E-06 AAGTGAGCTGAGATCAC 17 V_OCT1_06_M00162 TRANSFAC + 39412244 39412257 3.0E-06 ATTAATTTGATATT 14 V_OSR1_04_M02888 TRANSFAC - 39412172 39412187 8.0E-06 TCAGGCTACCAAATCA 16 V_DMRT2_01_M01147 TRANSFAC + 39408645 39408660 2.0E-06 TATAGGAATACAATGT 16 V_MYF6_03_M02781 TRANSFAC - 39408785 39408800 8.0E-06 GAGAAACAGCTGACTT 16 V_HNF1A_Q5_M02013 TRANSFAC + 39408493 39408503 6.0E-06 AGCTAATCATT 11 V_HOXD8_01_M01432 TRANSFAC - 39412239 39412255 7.0E-06 TATCAAATTAATGTTTT 17 V_PAX4_02_M00377 TRANSFAC - 39408384 39408394 9.0E-06 AAAAAATTAGA 11 V_SOX15_04_M02903 TRANSFAC + 39408777 39408791 4.0E-06 GTAAATGAAAGTCAG 15 V_FOXO4_01_M00472 TRANSFAC - 39412192 39412202 4.0E-06 AAAAACAAGTT 11 V_BRN3C_01_M01408 TRANSFAC - 39412238 39412253 8.0E-06 TCAAATTAATGTTTTC 16 V_CMAF_01_M01070 TRANSFAC - 39408685 39408703 5.0E-06 ATAAGTGCTGACAGGATGA 19 V_IPF1_04_M01236 TRANSFAC + 39412243 39412252 6.0E-06 CATTAATTTG 10 V_OBOX5_01_M01381 TRANSFAC - 39403480 39403496 1.0E-06 AGCTGGGATTATTTAAA 17 V_OTX1_01_M01366 TRANSFAC - 39403480 39403496 9.0E-06 AGCTGGGATTATTTAAA 17 V_OBOX6_06_M03067 TRANSFAC + 39403480 39403496 1.0E-06 TTTAAATAATCCCAGCT 17

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